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https://www.readbyqxmd.com/read/27927806/sleep-neurophysiological-dynamics-through-the-lens-of-multitaper-spectral-analysis
#1
REVIEW
Michael J Prerau, Ritchie E Brown, Matt T Bianchi, Jeffrey M Ellenbogen, Patrick L Purdon
During sleep, cortical and subcortical structures within the brain engage in highly structured oscillatory dynamics that can be observed in the electroencephalogram (EEG). The ability to accurately describe changes in sleep state from these oscillations has thus been a major goal of sleep medicine. While numerous studies over the past 50 years have shown sleep to be a continuous, multifocal, dynamic process, long-standing clinical practice categorizes sleep EEG into discrete stages through visual inspection of 30-s epochs...
January 2017: Physiology
https://www.readbyqxmd.com/read/27923944/membrane-oxygenator-use-with-biventricular-assist-device-facilitation-of-support-and-lung-recovery
#2
Kristen Nelson-McMillan, William J Ravekes, William R Thompson, Kristen M Brown, Larry Wolff, Rajeev S Wadia, LeAnn M McNamara, Donald H Shaffner, Ivor D Berkowitz, Marshall L Jacobs, Luca A Vricella
We present the use of a low-resistance membrane oxygenator (Quadrox D, Maquet) in series with a pulsatile right ventricular assist device (Berlin Heart EXCOR, Berlin Heart) in a patient with biventricular support who required high-frequency oscillatory ventilation (HFOV), due to refractory acute respiratory distress syndrome associated with Cytomegalovirus pneumonia. The high mean airway pressure associated with the use of HFOV resulted in a significant negative impact on left ventricular assist device (LVAD) filling that led to a combined respiratory and metabolic acidosis and the need for vasopressor support...
December 6, 2016: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/27915117/from-intentions-to-actions-neural-oscillations-encode-motor-processes-through-phase-amplitude-and-phase-amplitude-coupling
#3
Etienne Combrisson, Marcela Perrone-Bertolotti, Juan Lp Soto, Golnoush Alamian, Philippe Kahane, Jean-Philippe Lachaux, Aymeric Guillot, Karim Jerbi
Goal-directed motor behavior is associated with changes in patterns of rhythmic neuronal activity across widely distributed brain areas. In particular, movement initiation and execution are mediated by patterns of synchronization and desynchronization that occur concurrently across distinct frequency bands and across multiple motor cortical areas. To date, motor-related local oscillatory modulations have been predominantly examined by quantifying increases or suppressions in spectral power. However, beyond signal power, spectral properties such as phase and phase-amplitude coupling (PAC) have also been shown to carry information with regards to the oscillatory dynamics underlying motor processes...
November 30, 2016: NeuroImage
https://www.readbyqxmd.com/read/27910862/methylphenidate-enhances-early-stage-sensory-processing-and-rodent-performance-of-a-visual-signal-detection-task
#4
Rachel L Navarra, Brian D Clark, Andrew T Gargiulo, Barry D Waterhouse
Methylphenidate (MPH) is used clinically to treat attention-deficit/hyperactivity disorder (ADHD) and off-label as a performance enhancing agent in healthy individuals. MPH enhances catecholamine transmission via blockade of norepinephrine (NE) and dopamine (DA) reuptake transporters. However, it is not clear how this action impacts neural circuits performing cognitive and sensorimotor functions driving performance enhancement. The dorsal lateral geniculate nucleus (dLGN) is the primary thalamic relay for visual information from the retina to the cortex and is densely innervated by NE-containing fibers from the locus coeruleus (LC), a pathway known to modulate state-dependent sensory processing...
December 2, 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27903720/oscillatory-dynamics-underlying-perceptual-narrowing-of-native-phoneme-mapping-from-6-to-12-months-of-age
#5
Silvia Ortiz-Mantilla, Jarmo A Hämäläinen, Teresa Realpe-Bonilla, April A Benasich
: During the first months of life, human infants process phonemic elements from all languages similarly. However, by 12 months of age, as language-specific phonemic maps are established, infants respond preferentially to their native language. This process, known as perceptual narrowing, supports neural representation and thus efficient processing of the distinctive phonemes within the sound environment. Although oscillatory mechanisms underlying processing of native and non-native phonemic contrasts were recently delineated in 6-month-old infants, the maturational trajectory of these mechanisms remained unclear...
November 30, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27900823/high-frequency-mechanostimulation-of-cell-adhesion
#6
Laith F Kadem, K Grace Suana, Michelle Holz, Wei Wang, Hannes Westerhaus, Rainer Herges, Christine Selhuber-Unkel
Cell adhesion is regulated by molecularly defined protein interactions and by mechanical forces, which can activate a dynamic restructuring of adhesion sites. Previous attempts to explore the response of cell adhesion to forces have been limited to applying mechanical stimuli that involve the cytoskeleton. In contrast, we here apply a new, oscillatory type of stimulus through push-pull azobenzenes. Push-pull azobenzenes perform a high-frequency, molecular oscillation upon irradiation with visible light that has frequently been applied in polymer surface relief grating...
November 30, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27898438/rescue-therapies-for-acute-respiratory-distress-syndrome-what-to-try-first
#7
Onnen Moerer, Tommaso Tonetti, Michael Quintel
PURPOSE OF REVIEW: Severe respiratory failure due to the acute respiratory distress syndrome (ARDS) might require rescue therapy measures beyond even extended standard care to ensure adequate oxygenation and survival. This review provides a summary and assessment of treatment options that can be beneficial when the standard approach fails. RECENT FINDINGS: 'Life-threatening' conditions or refractory hypoxemia during mechanical ventilation are more a matter of personal rating than an objective diagnosis based on defined and/or unanimously agreed thresholds that would mandate the use of rescue therapies...
November 24, 2016: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/27882025/no-inhalation-in-combination-with-high-frequency-ventilation-treatment-in-the-treatment-of-neonatal-severe-respiratory-failure
#8
Xiaohui Guo, Yanfeng Sun, Jing Miao, Min Cui, Jiangbo Wang, Shuzhen Han
OBJECTIVE: To discuss over NO inhalation (iNO) in combination with high frequency ventilation treatment in relieving clinical symptoms and respiratory state of patients with neonatal severe respiratory failure. METHODS: Ninety newborns with severe respiratory failure who received treatment in our hospital were selected for this study. They were divided into research group and control group according to visiting time. Patients in the control group were given conventional treatment in combination with high-frequency oscillatory ventilation, while patients in the research group were given iNO for treatment additionally besides the treatment the same as the control group...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27874934/effect-of-nitric-oxide-inhalation-for-the-treatment-of-neonatal-pulmonary-hypertension
#9
H-W Wu, Z-G Li, G Liu, G-Z Lu, H-Y Liang
OBJECTIVE: To investigate the effect of nitric oxide (NO) inhalation for the treatment of neonatal pulmonary hypertension. PATIENTS AND METHODS: Eighty-six patients with neonatal pulmonary hypertension who were treated for the first time Xuzhou Children's Hospital from January 2013 to January 2016 were selected and randomly divided into the observation group and control group, with 43 cases each. Patients in the control group were treated with high-frequency oscillatory ventilation, while those in the observation group were treated with high-frequency oscillatory ventilation combined with inhalational NO therapy...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27862666/filling-the-void-enriching-the-feature-space-of-successful-stopping
#10
René J Huster, Signe Schneider, Christina F Lavallee, Stefanie Enriquez-Geppert, Christoph S Herrmann
The ability to inhibit behavior is crucial for adaptation in a fast changing environment and is commonly studied with the stop signal task. Current EEG research mainly focuses on the N200 and P300 ERPs and corresponding activity in the theta and delta frequency range, thereby leaving us with a limited understanding of the mechanisms of response inhibition. Here, 15 functional networks were estimated from time-frequency transformed EEG recorded during processing of a visual stop signal task. Cortical sources underlying these functional networks were reconstructed, and a total of 45 features, each representing spectrally and temporally coherent activity, were extracted to train a classifier to differentiate between go and stop trials...
November 11, 2016: Human Brain Mapping
https://www.readbyqxmd.com/read/27858670/viscoelastic-properties-of-normal-rat-liver-measured-by-ultrasound-elastography-comparison-with-oscillatory-rheometry
#11
Haoming Lin, Yuanyuan Shen, Xin Chen, Ying Zhu, Yi Zheng, Xinyu Zhang, Yanrong Guo, Tianfu Wang, Siping Chen
BACKGROUND: Ultrasound elastography has been widely used to measure liver stiffness. However, the accuracy of liver viscoelasticity obtained by ultrasound elastography has not been well established. OBJECTIVE: To assess the accuracy of ultrasound elastography for measuring liver viscoelasticity and compare to conventional rheometry methods. In addition, to determine if combining these two methods could delineate the rheological behavior of liver over a wide range of frequencies...
November 14, 2016: Biorheology
https://www.readbyqxmd.com/read/27857217/giant-frequency-down-conversion-of-the-dancing-acoustic-bubble
#12
P A Deymier, M Keswani, N Jenkins, C Tang, K Runge
We have demonstrated experimentally the existence of a giant frequency down-conversion of the translational oscillatory motion of individual submillimeter acoustic bubbles in water in the presence of a high frequency (500 kHz) ultrasonic standing wave. The frequency of the translational oscillations (~170 Hz) is more than three orders of magnitude smaller than that of the driving acoustic wave. We elucidate the mechanism of this very slow oscillation with an analytical model leading to an equation of translational motion of a bubble taking the form of Mathieu's equation...
November 18, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27851594/1960-a-case-of-bell-palsy-associated-with-high-frequency-oscillatory-ventilation-in-a-pediatric-patient
#13
Brisa Gulari, Adebayo Adeyinka, Keneisha Bailey, Louisdon Pierre
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27842745/managing-acute-lung-injury
#14
REVIEW
Gregory A Schmidt
The foundation of mechanical ventilation for acute respiratory distress syndrome involves limiting lung overdistention by using small tidal volumes or transpulmonary pressures. Potential for additional lung recruitment with higher positive end-expiratory pressure (PEEP) should be assessed. When stress index indicates tidal recruitment-derecruitment, PEEP is increased to higher values. Alternatively, a high PEEP table is used in all patients. When these conventional approaches are insufficient to sustain acceptable gas exchange, rescue is attempted using extracorporeal therapies, airway pressure-release ventilation, inhaled vasodilators, or high-frequency oscillatory ventilation...
December 2016: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/27842540/the-impact-of-low-frequency-low-force-cyclic-stretching-of-human-bronchi-on-airway-responsiveness
#15
Morgan Le Guen, Stanislas Grassin-Delyle, Emmanuel Naline, Amparo Buenestado, Marion Brollo, Elisabeth Longchampt, Philippe Kleinmann, Philippe Devillier, Christophe Faisy
BACKGROUND: In vivo, the airways are constantly subjected to oscillatory strain (due to tidal breathing during spontaneous respiration) and (in the event of mechanical ventilation) positive pressure. This exposure is especially problematic for the cartilage-free bronchial tree. The effects of cyclic stretching (other than high-force stretching) have not been extensively characterized. Hence, the objective of the present study was to investigate the functional and transcriptional response of human bronchi to repetitive mechanical stress caused by low-frequency, low-force cyclic stretching...
November 14, 2016: Respiratory Research
https://www.readbyqxmd.com/read/27835024/shear-banding-of-soft-glassy-materials-in-large-amplitude-oscillatory-shear
#16
Rangarajan Radhakrishnan, Suzanne M Fielding
We study shear banding in soft glassy materials subject to a large amplitude oscillatory shear flow (LAOS). By numerical simulations of the widely used soft glassy rheology model, supplemented by more general physical arguments, we demonstrate strong banding over an extensive range of amplitudes and frequencies of the imposed shear rate γ[over ˙](t)=γ[over ˙]_{0}cos(ωt), even in materials that do not permit banding as their steady state response to a steadily imposed shear flow γ[over ˙]=γ[over ˙]_{0}=const...
October 28, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27834669/a-translational-cellular-model-to-study-the-impact-of-high-frequency-oscillatory-ventilation-hfov-on-human-epithelial-cell-function
#17
Anja Karolin Mowes, Beatriz E de Jongh, Timothy Cox, Yan Zhu, Thomas H Shaffer
High frequency oscillatory ventilation (HFOV) has been proposed as gentle ventilation strategy to prevent lung injury in the preterm infant. High frequency ventilation leads to dimensional and mechanical airway deformation in animal airway models, which is consistent with translational studies demonstrating the impact of oxygen and biophysical stresses on normal airway cellular function. There is an overall paucity of clinical and cellular data on the impact of HFOV on the conducting airway. We developed an innovative method to test the impact of the clinical HFO Ventilator (Sensormedic 3100A) on human epithelial cell function...
November 10, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27830650/relationships-between-cortical-myeloarchitecture-and-electrophysiological-networks
#18
Benjamin A E Hunt, Prejaas K Tewarie, Olivier E Mougin, Nicolas Geades, Derek K Jones, Krish D Singh, Peter G Morris, Penny A Gowland, Matthew J Brookes
The human brain relies upon the dynamic formation and dissolution of a hierarchy of functional networks to support ongoing cognition. However, how functional connectivities underlying such networks are supported by cortical microstructure remains poorly understood. Recent animal work has demonstrated that electrical activity promotes myelination. Inspired by this, we test a hypothesis that gray-matter myelin is related to electrophysiological connectivity. Using ultra-high field MRI and the principle of structural covariance, we derive a structural network showing how myelin density differs across cortical regions and how separate regions can exhibit similar myeloarchitecture...
November 22, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27821136/the-network-sustaining-action-myoclonus-a-meg-emg-study-in-patients-with-epm1
#19
Silvana Franceschetti, Laura Canafoglia, Fabio Rotondi, Elisa Visani, Alice Granvillano, Ferruccio Panzica
BACKGROUND: To explore the cortical network sustaining action myoclonus and to found markers of the resulting functional impairment, we evaluated the distribution of the cortico-muscular coherence (CMC) and the frequency of coherent cortical oscillations with magnetoencephalography (MEG). All patients had EPM1 (Unverricht-Lundborg) disease known to present with prominent and disabling movement-activated myoclonus. METHODS: Using autoregressive models, we evaluated CMC on MEG sensors grouped in regions of interests (ROIs) above the main cortical areas...
November 7, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27817768/-clinical-effect-of-high-frequency-oscillatory-ventilation-combined-with-pulmonary-surfactant-in-treatment-of-neonatal-severe-meconium-aspiration-syndrome-complicated-by-pulmonary-hemorrhage
#20
Jing Huang, Xin-Zhu Lin, Zhi Zheng
OBJECTIVE: To study the clinical effect and safety of high-frequency oscillatory ventilation (HFOV) combined with pulmonary surfactant (PS) in the treatment of neonatal severe meconium aspiration syndrome (MAS) complicated by neonatal pulmonary hemorrhage (NPH). METHODS: A total of 48 children with severe MAS complicated by NPH were enrolled, and a retrospective analysis was performed for the clinical effects of HFOV+PS (trial group, 25 children) and HFOV alone (control group, 23 children)...
November 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
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