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https://www.readbyqxmd.com/read/29417643/high-throughput-image-cytometry-micronucleus-assay-to-investigate-the-presence-or-absence-of-mutagenic-effects-of-cold-physical-plasma
#1
Sander Bekeschus, Anke Schmidt, Axel Kramer, Hans-Robert Metelmann, Frank Adler, Thomas von Woedtke, Felix Niessner, Klaus-Dieter Weltmann, Kristian Wende
Promising cold physical plasma sources have been developed in the field of plasma medicine. An important prerequisite to their clinical use is lack of genotoxic effects in cells. During optimization of one or even different plasma sources for a specific application, large numbers of samples need to be analyzed. There are soft and easy-to-assess markers for genotoxic stress such as phosphorylation of histone H2AX (γH2AX) but only few tests are accredited by the OECD with regard to mutagenicity detection. The micronucleus (MN) assay is among them but often requires manual counting of many thousands of cells per sample under the microscope...
February 8, 2018: Environmental and Molecular Mutagenesis
https://www.readbyqxmd.com/read/29401839/enhancement-of-high-order-harmonics-in-a-plasma-waveguide-formed-in-clustered-ar-gas
#2
Xiaotao Geng, Shiyang Zhong, Guanglong Chen, Weijun Ling, Xinkui He, Zhiyi Wei, Dong Eon Kim
Generation of high-order harmonics (HHs) is intensified by using a plasma waveguide created by a laser in a clustered gas jet. The formation of a plasma waveguide and the guiding of a laser beam are also demonstrated. Compared to the case without a waveguide, harmonics were strengthened up to nine times, and blue-shifted. Numerical simulation by solving the time-dependent Schrödinger equation in strong field approximation agreed well with experimental results. This result reveals that the strengthening is the result of improved phase matching and that the blue shift is a result of change in fundamental laser frequency due to self-phase modulation (SPM)...
February 5, 2018: Optics Express
https://www.readbyqxmd.com/read/29400781/fiber-coupled-ultrashort-pulse-laser-based-electronic-excitation-tagging-velocimetry
#3
Paul S Hsu, Naibo Jiang, Paul M Danehy, James R Gord, Sukesh Roy
Transmission of intense ultrashort laser pulses through hollow-core fibers (HCFs) is investigated for molecular-tagging velocimetry. A low-vacuumed HCF beam-delivery system is developed to transmit high-peak-power pulses. Vacuum pressure effects on transmission efficiency and nonlinear effects at the fiber output are studied for 100 ps and 100 fs laser beams. With a 0.1 bar vacuum in the fiber, transmission efficiency increases by ∼30%, while spectral broadening is reduced. A 1 m long, 1 mm core metal-dielectric-coated HCF can transmit ∼45  mJ/pulse and ∼2...
January 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29386633/a-peculiar-low-luminosity-short-gamma-ray-burst-from-a-double-neutron-star-merger-progenitor
#4
B-B Zhang, B Zhang, H Sun, W-H Lei, H Gao, Y Li, L Shao, Y Zhao, Y-D Hu, H-J Lü, X-F Wu, X-L Fan, G Wang, A J Castro-Tirado, S Zhang, B-Y Yu, Y-Y Cao, E-W Liang
Double neutron star (DNS) merger events are promising candidates of short gamma-ray burst (sGRB) progenitors as well as high-frequency gravitational wave (GW) emitters. On August 17, 2017, such a coinciding event was detected by both the LIGO-Virgo gravitational wave detector network as GW170817 and Gamma-Ray Monitor on board NASA's Fermi Space Telescope as GRB 170817A. Here, we show that the fluence and spectral peak energy of this sGRB fall into the lower portion of the distributions of known sGRBs. Its peak isotropic luminosity is abnormally low...
January 31, 2018: Nature Communications
https://www.readbyqxmd.com/read/29373164/high-frequency-jet-ventilation-during-endolaryngeal-surgery-risk-factors-for-complications
#5
Demet Altun, Emre Çamcı, Mukadder Orhan-Sungur, Nükhet Sivrikoz, Bora Başaran, Tülay Özkan-Seyhan
No abstract text is available yet for this article.
January 17, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29347174/periodic-jetting-and-monodisperse-jet-drops-from-oblique-gas-injection
#6
Oliver McRae, Antoine Gaillard, James C Bird
When air is blown in a straw or tube near an air-liquid interface, typically one of two behaviors is observed: a dimple in the liquid's surface, or a frenzy of sputtering bubbles, waves, and spray. Here we report and characterize an intermediate regime that can develop when a confined air jet enters the interface at an angle. This regime is oscillatory with a distinct characteristic frequency and can develop periodic angled jets that can break up into monodisperse aerosols. The underlying mechanisms responsible for this highly periodic regime are not well understood...
July 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347084/identifying-the-linear-phase-of-the-relativistic-kelvin-helmholtz-instability-and-measuring-its-growth-rate-via-radiation
#7
R Pausch, M Bussmann, A Huebl, U Schramm, K Steiniger, R Widera, A Debus
For the relativistic Kelvin-Helmholtz instability (KHI), which occurs at shear interfaces between two plasma streams, we report results on the polarized radiation over all observation directions and frequencies emitted by the plasma electrons from ab initio kinetic simulations. We find the polarization of the radiation to provide a clear signature for distinguishing the linear phase of the KHI from its other phases. During the linear phase, we predict the growth rate of the KHI radiation power to match the growth rate of the KHI to a high degree...
July 2017: Physical Review. E
https://www.readbyqxmd.com/read/29328542/towards-the-detection-of-explosive-taggants-microwave-and-millimetre-wave-gas-phase-spectroscopies-of-3-nitrotoluene
#8
Anthony Roucou, Isabelle Kleiner, Manuel Goubet, Sabath Bteich, Gaël Mouret, Robin Bocquet, Francis Hindle, W Leo Meerts, Arnaud Cuisset
The monitoring of gas phase mononitrotoluenes is crucial for defence, civil security and environmental interests since they are used as taggant for TNT detection and in the manufacturing of industrial compounds such as dyestuffs. In this study, we have succeeded to measure and analyse at high resolution a room temperature rotationally resolved millimeter-wave spectrum of meta-nitrotoluene(3-NT). Experimental and theoretical difficulties have been overcome, in particular, those related to the low vapour pressure of 3-NT and to the presence of a CH$_3$ internal rotation in an almost free rotation regime ($V_3$=6...
January 12, 2018: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/29326116/behavioural-responses-to-infrasonic-particle-acceleration-in-cuttlefish
#9
Maria Wilson, Jens Ådne Rekkedal Haga, Hans Erik Karlsen
Attacks by aquatic predators generate frontal water disturbances characterised by low-frequency gradients in pressure and particle motion. Low-frequency hearing is highly developed in cephalopods. Thus, we examined behavioural responses in juvenile cuttlefish to infrasonic accelerations mimicking main aspects of the hydrodynamic signals created by predators. In the experimental set-up, animals and their surrounding water moved as a unit to minimise lateral line activation and to allow examination of the contribution by the inner ear...
January 11, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29324051/anti-il-8-antibody-potentiates-the-effect-of-exogenous-surfactant-in-respiratory-failure-caused-by-meconium-aspiration
#10
Pavol Mikolka, Jana Kopincova, Petra Kosutova, Maros Kolomaznik, Andrea Calkovska, Daniela Mokra
AIM: Meconium aspiration syndrome (MAS) is life-threatening respiratory failure of newborns which can be treated by exogenous surfactant. In response to meconium, increased levels of chemokine IL-8 (CXCL8) stimulate massive neutrophil infiltration of the lungs. Local accumulation and activation of neutrophils, on-going inflammation, lung edema, and oxidative damage contribute to inactivation of endogenous and therapeutically given surfactants. Therefore, we have hypothesized that addition of monoclonal anti-IL-8 antibody into exogenous surfactant can mitigate the neutrophil-induced local injury and the secondary surfactant inactivation and may finally result in improvement of respiratory functions...
January 11, 2018: Experimental Lung Research
https://www.readbyqxmd.com/read/29240436/high-resolution-infrared-spectra-of-the-%C3%AE-1-fundamental-bands-of-mono-substituted-13c-propyne-isotopologues
#11
Kirstin D Doney, Dongfeng Zhao, Harold H Linnartz
We present a combined experimental and ab initio study on the jet-cooled high- resolution infrared spectra of the ν1 (acetylenic stretch) fundamental band for three isotopologues of propyne: 13CH312C≡12CH, 12CH313C≡12CH, and 12CH312C≡13CH. The experimental spectra are recorded in natural abundance using a continuous supersonic expansion of regular propyne diluted in argon and helium, in combination with continuous wave cavity ring-down spectroscopy (cw-CRDS). The fully rotationally resolved K' = 0 and 1 subbands of all three mono-substituted 13C isotopologues have been measured near 3330 cm-1, and their spectroscopic analysis is presented here for the first time...
December 14, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29238695/high-frequency-jet-ventilation-during-transoral-laser-microsurgery-for-tis-t2-laryngeal-cancer
#12
Francesco Mora, Francesco Missale, Fabiola Incandela, Marta Filauro, Giampiero Parrinello, Alberto Paderno, Palmiro Della Casa, Cesare Piazza, Giorgio Peretti
Background: Transoral laser microsurgery (TLM) for early to intermediate laryngeal squamous cell cancer (SCC) can be technically challenging when adequate exposure of the posterior laryngeal compartment is required due to the presence of the orotracheal tube. The goal of our study was to analyze the efficacy of high frequency jet ventilation (HFJV) in achieving appropriate laryngeal exposure and safe oncologic resection of lesions located in such a position. Methods: We reviewed the clinical records of 62 patients affected by Tis-T2 SCC of the posterior laryngeal compartment treated by TLM between 02/2012 and 12/2016...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/29221295/contralateral-thoracoscopic-lobectomy-in-postlobectomy-patients
#13
Manabu Yasuda, Ryoichi Nakanishi, Shinji Shinohara, Masataka Mori, Syuhei Ashikari, Tsunehiro Oyama, Takeshi Hanagiri
Background: It is difficult to perform thoracoscopic lobectomy in patients with a history of contralateral lobectomy, as stable oxygenation is not always maintained under conditions of one-lung ventilation during surgery. Methods: This study evaluated 14 patients who underwent thoracoscopic lobectomy after previously undergoing contralateral lobectomy at a single institution between 2008 and 2015. Results: Among 14 patients who had previously received contralateral lobectomy, 4 were unable to maintain sufficient perioperative oxygenation with usual one-lung ventilation...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29189750/multi-source-generation-mechanisms-for-low-frequency-noise-induced-by-flood-discharge-and-energy-dissipation-from-a-high-dam-with-a-ski-jump-type-spillway
#14
Jijian Lian, Xiaoqun Wang, Wenjiao Zhang, Bin Ma, Dongming Liu
As excess water is discharged from a high dam, low frequency noise (air pulsation lower than 10 Hz, LFN) is generated and propagated in the surrounding areas, causing environmental hazards such as the vibration of windows and doors and the discomfort of local residents. To study the generation mechanisms and key influencing factors of LFN induced by flood discharge and energy dissipation from a high dam with a ski-jump type spillway, detailed prototype observations and analyses of LFN are carried out. The discharge flow field is simulated and analyzed using a gas-liquid turbulent flow model...
November 30, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29173320/pulmonary-artery-pressures-in-school-age-children-born-prematurely
#15
RANDOMIZED CONTROLLED TRIAL
Sanja Zivanovic, Kuberan Pushparajah, Sandy Calvert, Neil Marlow, Reza Razavi, Janet L Peacock, Anne Greenough
OBJECTIVES: To test the hypothesis that pulmonary artery pressures were higher in school aged children born extremely premature than those born at term. We also wanted to assess whether pulmonary artery pressures differed between children born prematurely with or without bronchopulmonary dysplasia (BPD) or between those randomized in the neonatal period to different ventilation modes. STUDY DESIGN: Transthoracic echocardiography was performed on 193 children born extremely premature (106 had BPD) and 110 children born at term when they were 11-14 years of age...
December 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29161293/high-intensity-focused-ultrasound-ablation-around-the-tubing
#16
Jun Yang Siu, Chenhui Liu, Yufeng Zhou
High-intensity focused ultrasound (HIFU) has been emerging as an effective and noninvasive modality in cancer treatment with very promising clinical results. However, a small vessel in the focal region could be ruptured, which is an important concern for the safety of HIFU ablation. In this study, lesion formation in the polyacrylamide gel phantom embedded with different tubing (inner diameters of 0.76 mm and 3 mm) at varied flow speeds (17-339 cm/s) by HIFU ablation was photographically recorded. Produced lesions have decreased length (~30%) but slightly increased width (~6%) in comparison to that without the embedded tubing...
2017: PloS One
https://www.readbyqxmd.com/read/29094601/droplet-formation-by-rupture-of-vibration-induced-interfacial-fingers
#17
Sze Yi Mak, Youchuang Chao, Shakurur Rahman, Ho Cheung Shum
By imposing vibration to a core-annular flow of an aqueous two-phase system (ATPS) with ultralow interfacial tension, we observe a liquid finger protruding from the interface of an expanding jet. We find that the protruded finger breaks up only when its length-to-width ratio exceeds a threshold value. The breakup follows a constant wavelength-to-width ratio that is consistent with that of breakup under Rayleigh-Plateau instability. The mechanism is applicable to aqueous two-phase systems with a large range of viscosity ratios...
November 2, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29091044/dispersion-risk-associated-with-surgical-debridement-devices
#18
Mark Granick, Liel Rubinsky, Chaitra Parthiban, Mayilvahanan Shanmugam, Narayanan Ramasubbu
INTRODUCTION: Surgical instrumentation is now available to facilitate wound debridement. The 2 primary options involve different energy applications, but both have the potential to spray. The Versajet II (Smith & Nephew, London, UK) utilizes a high-powered water jet to disrupt tissue and remove debris by means of the Venturi effect. The SonicVac (Misonix, Farmingdale, NY) is a direct-contact, low-frequency ultrasound debriding device. It delivers a high-energy ultrasound to a wound surface via a fluid medium, causing bubble cavitation, a physical effect of rapid pressure waves causing bubbles to form and implode that releases mechanical energy...
October 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29060368/a-gaussian-process-regression-model-for-walking-speed-estimation-using-a-head-worn-imu
#19
Shaghayegh Zihajehzadeh, Edward J Park
Miniature inertial sensors mainly worn on waist, ankle and wrist have been widely used to measure walking speed of the individuals for lifestyle and/or health monitoring. Recent emergence of head-worn inertial sensors in the form of a smart eyewear (e.g. Recon Jet) or a smart ear-worn device (e.g. Sensixa e-AR) provides an opportunity to use these sensors for estimation of walking speed in real-world environment. This work studies the feasibility of using a head-worn inertial sensor for estimation of walking speed...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29038412/-effects-of-high-frequency-jet-ventilation-on-respiratory-failure-after-total-arch-replacement-due-to-acute-aortic-dissection-with-morbid-obesity-report-of-a-case
#20
Motoyuki Kumagai, Junichiro Nishizawa, Kazuhiro Takatoku, Takashi Ohba
A 55-year-old morbidly obese woman [body mass index (BMI) 51.2] developed acute type A aortic dissection, and she also presented with significant hypoxemia and hypercapnia. She underwent a successful emergency total arch replacement, but severe hypoxemia persisted and Pao2/Fio2 lowered to 71.9 mmHg. We therefore applied high frequency jet ventilation (HFJV), which soon improved the hypoxemia without hemodynamic compromise. HFJV was discontinued three days later, when her Pao2/Fio2 improved to 170.0 mmHg. Weaning from the respirator was initiated on postoperative day 13...
October 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
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