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Tobias Stalder, Susann Steudte-Schmiedgen, Nina Alexander, Tim Klucken, Annika Vater, Susann Wichmann, Clemens Kirschbaum, Robert Miller
The analysis of hair cortisol concentrations (HCC) is a relatively new strategy to measure long-term cumulative cortisol levels, which is increasingly used in psychoneuroendocrinological research. Here, we conduct a first comprehensive meta-analysis of HCC research based on aggregated data from a total of 124 (sub)samples (66 independent studies; total N=10,289). We seek to answer two central questions: (i) Which covariates and basic features of HCC need to be considered in future research? (ii) What are the main determinants of HCC in terms of chronic stress exposure and mental health? Concerning basic characteristics, our findings identify several covariates to be considered (age, sex, hair washing frequency, hair treatment, oral contraceptive use), confirm a decline of HCC from the first to the second proximal 3cm hair segment, and show positive associations between HCC and short-term salivary cortisol measures...
March 2017: Psychoneuroendocrinology
A Flöck, S K Weber, N Ferrari, C Fietz, C Graf, R Fimmers, U Gembruch, W M Merz
No abstract text is available yet for this article.
November 18, 2016: Psychoneuroendocrinology
Giacomo Ciocca, Erika Limoncin, Eleonora Carosa, Stefania Di Sante, Giovanni L Gravina, Daniele Mollaioli, Daniele Gianfrilli, Andrea Lenzi, Emmanuele A Jannini
INTRODUCTION: Testosterone is fundamental for psychological, sexological, cognitive, and reproductive aspects, and its lack or reduction largely impacts the quality of life in males and females. AIM: Therefore, the aim of this review is to describe the role of testosterone in the neurophysiology of the brain and related aspects regarding the quality of general and sexual life. METHODS: We listed and discussed the principal studies on the role of testosterone in the brain regarding sexual health, psychopathological conditions, and the elderly...
January 2016: Sexual Medicine Reviews
Gina-Isabelle Henze, Sandra Zänkert, David F Urschler, Tanja J Hiltl, Brigitte M Kudielka, Jens C Pruessner, Stefan Wüst
The Trier Social Stress Test (TSST) is the most widely used laboratory stress protocol in psychoneuroendocrinology. Despite its popularity, surprisingly few attempts have been made to explore the ecological validity of the TSST. In the present study, 31 young healthy subjects (24 females) were exposed to the TSST about 4 weeks before completing an oral exam on a separate day. Salivary cortisol levels increased significantly in response to both stimuli (TSST: F(2.21, 66.33)=5.73, p=0.004; oral exam: F(1.98, 59...
January 2017: Psychoneuroendocrinology
Lauren M Federici, Izabela Facco Caliman, Andrei I Molosh, Stephanie D Fitz, William A Truitt, Pascal Bonaventure, Janet S Carpenter, Anantha Shekhar, Philip L Johnson
No abstract text is available yet for this article.
November 2016: Psychoneuroendocrinology
Tuong-Vi Nguyen, James T McCracken, Matthew D Albaugh, Kelly N Botteron, James J Hudziak, Simon Ducharme
No abstract text is available yet for this article.
July 25, 2016: Psychoneuroendocrinology
Rebecca M Reynolds
No abstract text is available yet for this article.
August 2016: Journal of Neuroendocrinology
Sabrina Kastaun, Tibo Gerriets, Marlene Tschernatsch, Mesut Yeniguen, Martin Juenemann
Great advances have been made in our understanding of Takotsubo syndrome in the past decade, but the aetiology of the condition remains incompletely understood. The most established theory, that catecholamine-mediated myocardial stunning is provoked by emotional or physiological stress, is supported by the presence of supraphysiological levels of plasma catecholamines in patients with Takotsubo syndrome. For this reason, the hyperexcitability of the autonomic nervous system under conditions of physical and emotional stress is often assessed in these patients...
November 2016: Nature Reviews. Cardiology
K C Chung, I Springer, L Kogler, B Turetsky, J Freiherr, B Derntl
No abstract text is available yet for this article.
June 1, 2016: Psychoneuroendocrinology
I N Karatsoreos
Anecdotally, we all know that stress is 'complicated', although most stress research is undertaken using incredibly simplified models that may not allow us to fully understand the underlying interactive mechanisms present in the 'real world'. This attempt at simplification, although sometimes necessary, may explain some of the difficulties faced when integrating basic science findings with the clinical and epidemiological data on stress and stress-related disorders. In a symposium held at the 2015 International Society for Psychoneuroendocrinology meeting in Edinburgh, UK, a series of speakers explored 'The Many Pathways to Plasticity in the Stress System', specifically focusing on variables that, in many cases, are eliminated from studies of stress to provide increased experimental control...
August 2016: Journal of Neuroendocrinology
Ching-Ju Chiu, Susan C Hu, Linda A Wray, Shang-Te Wu
BACKGROUND/PURPOSE: The short- and long-term impacts of behavioral and psychological factors on the diabetes and cognitive function relationship are not fully understood. This study examined levels and rates of change in age trajectories of cognitive function in middle-aged and older adults with and without diabetes who participated in different health behaviors. METHODS: Participants aged 53 and above with and without diabetes were drawn from the 1999 Taiwan Longitudinal Study of Aging (N = 4076, mean age 69...
June 2016: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
Alain Marchand, Robert-Paul Juster, Sonia J Lupien, Pierre Durand
Salivary alpha-amylase (sAA) is a stress-sensitive biomarker the shows promise as an indirect proxy of sympathetic-adrenal-medullary axis activities that are otherwise difficult to discern non-invasively. This comprehensive study investigated diurnal sAA in association with numerous psychosocial characteristics related to mental health, work stress, and non-work stress. Participants included 395 workers (56.1% women, age: M=41.3, SD=10.81) from across 34 distinct workplaces. Diurnal sAA was sampled over two non-consecutive work days at awakening, 30 min after awakening, 14h00, 16h00, and bedtime...
April 2016: Psychoneuroendocrinology
B Greenwood-Van Meerveld, R D Moloney, A C Johnson, M Vicario
Visceral pain is a term describing pain originating from the internal organs of the body and is a common feature of many disorders, including irritable bowel syndrome (IBS). Stress is implicated in the development and exacerbation of many visceral pain disorders. Recent evidence suggests that stress and the gut microbiota can interact through complementary or opposing factors to influence visceral nociceptive behaviours. The Young Investigator Forum at the International Society of Psychoneuroendocrinology (ISPNE) annual meeting reported experimental evidence suggesting the gut microbiota can affect the stress response to affect visceral pain...
August 2016: Journal of Neuroendocrinology
Tobias Stalder, Clemens Kirschbaum, Brigitte M Kudielka, Emma K Adam, Jens C Pruessner, Stefan Wüst, Samantha Dockray, Nina Smyth, Phil Evans, Dirk H Hellhammer, Robert Miller, Mark A Wetherell, Sonia J Lupien, Angela Clow
The cortisol awakening response (CAR), the marked increase in cortisol secretion over the first 30-45 min after morning awakening, has been related to a wide range of psychosocial, physical and mental health parameters, making it a key variable for psychoneuroendocrinological research. The CAR is typically assessed from self-collection of saliva samples within the domestic setting. While this confers ecological validity, it lacks direct researcher oversight which can be problematic as the validity of CAR measurement critically relies on participants closely following a timed sampling schedule, beginning with the moment of awakening...
January 2016: Psychoneuroendocrinology
Emmanuel Stip
In its current form, the Département de psychiatrie at the Université de Montréal (UdeM) was created in 1964. The first person to have headed was Dr. Gerard Beaudoin… Between 1948 and 1964, several others psychiatrists were heading the Département without necessary bearing a particular title.The directors of the Département from 1951 to now were: Drs. Fernand Côté, Camille Laurin, Gerard Beaudoin, Yvon Gauthier, Arthur Amyot, Francis Borgeat, Hugues Cormier, Sylvain Palardy, Jean Hébert, and Emmanuel Stip...
2015: Santé Mentale Au Québec
Gustavo E Tafet, Charles B Nemeroff
The role of stress in the origin and development of depression may be conceived as the result of multiple converging factors, including the chronic effect of environmental stressors and the long-lasting effects of stressful experiences during childhood, all of which may induce persistent hyperactivity of the hypothalamic-pituitary-adrenal axis. These changes, including increased availability of corticotropin-releasing factor and cortisol, are also associated with hyperactivity of the amygdala, hypoactivity of the hippocampus, and decreased serotonergic neurotransmission, which together result in increased vulnerability to stress...
2016: Journal of Neuropsychiatry and Clinical Neurosciences
Gregory A Miller
No abstract text is available yet for this article.
November 2015: Psychoneuroendocrinology
J D Woolley, B Chuang, O Lam, W Lai, A O'Donovan, K P Rankin, D H Mathalon, S Vinogradov
No abstract text is available yet for this article.
November 22, 2014: Psychoneuroendocrinology
Maren Schmidt-Kassow, Nadine Zink, Julia Mock, Christian Thiel, Lutz Vogt, Cornelius Abel, Jochen Kaiser
Moderate physical activity improves various cognitive functions, particularly when it is applied simultaneously to the cognitive task. In two psychoneuroendocrinological within-subject experiments, we investigated whether very low-intensity motor activity, i.e. walking, during foreign-language vocabulary encoding improves subsequent recall compared to encoding during physical rest. Furthermore, we examined the kinetics of brain-derived neurotrophic factor (BDNF) in serum and salivary cortisol. Previous research has associated both substances with memory performance...
2014: Behavioral and Brain Functions: BBF
Danielle M J de Veld, J Marianne Riksen-Walraven, Carolina de Weerth
Knowledge about children's stress reactivity and its correlates is mostly based on one stress task, making it hard to assess the generalizability of the results. The development of an additional stress paradigm for children, that also limits stress exposure and test time, could greatly advance this field of research. Research in adults may provide a starting point for the development of such an additional stress paradigm, as changes in salivary cortisol and alpha-amylase (sAA) over a 1-h pre-stress period in the laboratory correlated strongly with subsequent reactivity to stress task (Balodis et al...
September 2014: Stress: the International Journal on the Biology of Stress
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