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https://www.readbyqxmd.com/read/28749578/a-descriptive-study-of-intentional-self-poisoning-from-new-zealand-national-registry-data
#1
Eeva-Katri Kumpula, Shyamala Nada-Raja, Pauline Norris, Paul Quigley
OBJECTIVE: Understanding which population groups intentionally poison themselves by overdose and which substances are used are key to developing prevention efforts for such injuries. This paper uses Ministry of Health (MOH) data to explore the demographic characteristics of those who intentionally self-poison and the substances used, identifies limitations of existing data collections and makes recommendations for the future. METHODS: MOH mortality data from 2000 to 2012, and public hospital presentation data from 2000-2014 of cases of intentional self-poisoning (ISP), and poisoning of undetermined intent (UDP), were examined...
July 27, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28749449/food-sources-of-sodium-intake-in-an-adult-mexican-population-a-sub-analysis-of-the-salmex-study
#2
Eloisa Colin-Ramirez, Ángeles Espinosa-Cuevas, Paola Vanessa Miranda-Alatriste, Verónica Ivette Tovar-Villegas, JoAnne Arcand, Ricardo Correa-Rotter
Excessive dietary sodium intake increases blood pressure and cardiovascular risk. In Western diets, the majority of dietary sodium comes from packaged and prepared foods (≈75%); however, in Mexico there is no available data on the main food sources of dietary sodium. The main objective of this study was to identify and characterize the major food sources of dietary sodium in a sample of the Mexican Salt and Mexico (SALMEX) cohort. Adult male and female participants of the SALMEX study who provided a complete and valid three-day food record during the baseline visit were included...
July 27, 2017: Nutrients
https://www.readbyqxmd.com/read/28748589/the-role-of-medical-abortion-in-the-implementation-of-the-law-on-voluntary-termination-of-pregnancy-in-uruguay
#3
Verónica Fiol, Leticia Rieppi, Rafael Aguirre, María Nozar, Mónica Gorgoroso, Francisco Coppola, Leonel Briozzo
OBJECTIVE: To evaluate the implementation of the law that liberalizes voluntary abortion in Uruguay and enables health services to offer these services to the population. METHODS: The legal and regulatory provisions are described and the national data-provided by the Ministry of Public Health's National Information System (SINADI)-on the number of voluntary terminations of pregnancy, the abortion method (medical or surgical), and whether it was performed as an outpatient or inpatient are analyzed...
August 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28748535/financial-incentives-and-physician-practice-participation-in-medicare-s-value-based-reforms
#4
Adam M Markovitz, Patricia P Ramsay, Stephen M Shortell, Andrew M Ryan
OBJECTIVES: To evaluate whether greater experience and success with performance incentives among physician practices are related to increased participation in Medicare's voluntary value-based payment reforms. DATA SOURCES/STUDY SETTING: Publicly available data from Medicare's Physician Compare (n = 1,278; January 2012 to November 2013) and nationally representative physician practice data from the National Survey of Physician Organizations 3 (NSPO3; n = 907,538; 2013)...
July 26, 2017: Health Services Research
https://www.readbyqxmd.com/read/28748223/phenoplasm-a-database-of-disruption-phenotypes-for-malaria-parasite-genes
#5
Theo Sanderson, Julian C Rayner
Two decades after the first Plasmodium transfection, attempts have been made to disrupt more than 3,151 genes in malaria parasites, across five Plasmodium species. While results from rodent malaria transfections have been curated and systematised, empowering large-scale analysis, phenotypic data from human malaria parasite transfections currently exists as individual reports scattered across a the literature. To facilitate systematic analysis of published experimental genetic data across Plasmodium species, we have built PhenoPlasm ( http://www...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/28748210/dataset-on-genetic-and-physiological-adults-responses-to-social-distress
#6
Andrea Bonassi, Tommaso Ghilardi, Anna Truzzi, Ilaria Cataldo, Atiqah Azhari, Peipei Setoh, Kazuyuki Shinohara, Gianluca Esposito
Both expectations towards interactions with conspecifics, and genetic predispositions, affect adults׳ social behaviors. However, the underlying mechanisms remain largely unknown. Here, we report data to investigate the interaction between genetic factors, (oxytocin receptor (OXTR) and serotonin transporter (5-HTTLPR) polymorphisms), and adult interactional patterns in shaping physiological responses to social distress. During the presentation of distress vocalizations (cries of human female, infants and bonobos) we assessed participants׳ (N = 42 males) heart rate (HR) and peripheral nose temperature, which index state of arousal and readiness to action...
August 2017: Data in Brief
https://www.readbyqxmd.com/read/28747380/identification-of-differentially-expressed-splice-variants-by-the-proteogenomic-pipeline-splicify
#7
Malgorzata A Komor, Thang Pham, Annemieke C Hiemstra, Sander R Piersma, Anne S Bolijn, Tim Schelfhorst, Pien M Delis-van Diemen, Marianne Tijssen, Robert P Sebra, Meredith Ashby, Gerrit A Meijer, Connie R Jimenez, Remond J A Fijneman
Proteogenomics, i.e. comprehensive integration of genomics and proteomics data, is a powerful approach identifying novel protein biomarkers. This is especially the case for proteins that differ structurally between disease and control conditions. As tumor development is associated with aberrant splicing, we focus on this rich source of cancer specific biomarkers. To this end, we developed a proteogenomic pipeline, Splicify, which is able to detect differentially expressed protein isoforms. Splicify is based on integrating RNA massive parallel sequencing data and tandem mass spectrometry proteomics data to identify protein isoforms resulting from differential splicing between two conditions...
July 26, 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28747331/assessing-the-causal-role-of-adiposity-on-disordered-eating-in-childhood-adolescence-and-adulthood-a-mendelian-randomization-analysis
#8
Zoe E Reed, Nadia Micali, Cynthia M Bulik, George Davey Smith, Kaitlin H Wade
Background: Observational studies have shown that higher body mass index (BMI) is associated with increased risk of developing disordered eating patterns. However, the causal direction of this relation remains ambiguous.Objective: We used Mendelian randomization (MR) to infer the direction of causality between BMI and disordered eating in childhood, adolescence, and adulthood.Design: MR analyses were conducted with a genetic score as an instrumental variable for BMI to assess the causal effect of BMI at age 7 y on disordered eating patterns at age 13 y with the use of data from the Avon Longitudinal Study of Parents and Children (ALSPAC) (n = 4473)...
July 26, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28746954/-trends-of-tobacco-and-alcohol-consumption-over-65-years-in-germany
#9
Ulrich John, Monika Hanke
Aim No estimation was available for tobacco and for alcohol consumption in Germany based on sales data that were provided for public use and suited for time trend analysis. Objectives To estimate trends of tobacco and alcohol consumption rates for the years 1950-2014. Methods Data on tobacco and alcohol consumption in the nation were retrieved from reports made by producers of beer, wine, or spirits to the Federal Statistics Office of Germany. Time trends over the 65 years were calculated using the program Joinpoint...
July 26, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28746743/the-incretin-concept-revised-the-origin-of-glp-1-s-insulinotropic-function-the-gut-the-islets-or-both
#10
Daisuke Yabe, Yusuke Seino, Yutaka Seino
Incretins comprise a pair of gut hormones, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), which are secreted in response to food ingestion and enhance glucose-dependent insulin secretion (GIIS) from pancreatic β-cells. Immediately after secretion, GLP-1 is degraded by dipeptidyl peptidase-4 (DPP-4) more rapidly than GIP, and circulating levels of biologically intact GLP-1 are substantially lower than those of biologically intact GIP. Therefore, there has been a debate on how the gut-derived GLP-1 exerts insulinotropic actions...
July 26, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28745394/opioids-for-chronic-non-cancer-pain-in-children-and-adolescents
#11
REVIEW
Tess E Cooper, Emma Fisher, Andrew L Gray, Elliot Krane, Navil Sethna, Miranda Al van Tilburg, Boris Zernikow, Philip J Wiffen
BACKGROUND: Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization guidelines for pharmacological treatments for children's persisting pain acknowledge that pain in children is a major public health concern of high significance in most parts of the world. While in the past, pain was largely dismissed and was frequently left untreated, views on children's pain have changed over time, and relief of pain is now seen as importantWe designed a suite of seven reviews on chronic non-cancer pain and cancer pain (looking at antidepressants, antiepileptic drugs, non-steroidal anti-inflammatory drugs, opioids, and paracetamol as priority areas) in order to review the evidence for children's pain utilising pharmacological interventions in children and adolescents...
July 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28744957/glandular-odontogenic-cyst-an-updated-analysis-of-169-cases-reported-in-the-literature
#12
REVIEW
Bruno Ramos Chrcanovic, Ricardo Santiago Gomez
OBJECTIVE: To integrate the available data published on glandular odontogenic cyst (GOC) into a comprehensive analysis of its clinical/radiologic and histopathological features. METHODS: An electronic search was undertaken in May/2017. Eligibility criteria included publications having enough clinical/radiological/histological information to confirm the diagnosis. RESULTS: 58 publications (169 GOCs) were included. The lesion was slightly more prevalent in men than in women...
July 26, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28743947/match-between-soaring-modes-of-black-kites-and-the-fine-scale-distribution-of-updrafts
#13
Carlos D Santos, Frank Hanssen, Antonio-Román Muñoz, Alejandro Onrubia, Martin Wikelski, Roel May, João P Silva
Understanding how soaring birds use updrafts at small spatial scales is important to identify ecological constraints of movement, and may help to prevent conflicts between wind-energy development and the conservation of wildlife. We combined high-frequency GPS animal tracking and fine-spatial-scale uplift modelling to establish a link between flight behaviour of soaring birds and the distribution of updrafts. We caught 21 black kites (Milvus migrans) and GPS-tracked them while flying over the Tarifa region, on the Spanish side of the Strait of Gibraltar...
July 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28743563/high-spatial-and-temporal-resolution-anthropogenic-heat-discharge-estimation-in-los-angeles-county-california
#14
Yuanfan Zheng, Qihao Weng
Anthropogenic heat flux (Qf), which originates through energy consumption from buildings, industrial plants, vehicle exhausts, and human metabolism releases, is an important component in the urban Surface Energy Balance (SEB) system, and is key to understanding of many urban environmental issues. The present study provided a hybrid Qf modeling approach, which combined the inventory and GIS approach to create a 365-day hourly Qf profile at 120 m spatial resolution in Los Angeles County, California, USA. Qf was estimated by separate calculation of heat release from buildings, traffics, and human metabolism, respectively...
July 22, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28743512/inferring-transcription-factor-activity-from-microarray-data-reveals-novel-targets-for-toxicological-investigations
#15
T M Souza, T van den Beucken, J C S Kleinjans, D G J Jennen
Transcription factors (TFs) are important modulators of the inducible portion of the transcriptome, and therefore relevant in the context of exposure to exogenous compounds. Current approaches to predict the activity of TFs in biological systems are usually restricted to a few entities at a time due to low-throughput techniques targeting a limited fraction of annotated human TFs. Therefore, high-throughput alternatives may help to identify new targets of mechanistic and predictive value in toxicological investigations...
July 22, 2017: Toxicology
https://www.readbyqxmd.com/read/28742993/performance-and-return-to-sport-after-achilles-tendon-repair-in-national-football-league-players
#16
Robert A Jack, Kyle R Sochacki, Stephanie S Gardner, Patrick C McCulloch, David M Lintner, Pedro E Cosculluela, Kevin E Varner, Joshua D Harris
BACKGROUND: Achilles tendon injuries are common in sports, including football. The purpose of this study was to determine (1) return-to-sport rate in National Football League (NFL) players following Achilles tendon repair, (2) postoperative career length and games per season, (3) pre- and postoperative performance, and (4) postoperative performance compared with control players matched by position, age, years of experience, and performance. METHODS: Publicly available records were used to identify NFL players who underwent Achilles tendon repair and matched controls were identified...
July 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28742608/epidemiology-of-injuries-in-women-s-lacrosse-implications-for-sport-level-and-sex-specific-injury-prevention-strategies
#17
Kim D Barber Foss, Ed Le Cara, Teri McCambridge, Richard Y Hinton, Adam Kushner, Gregory D Myer
OBJECTIVE: By the end of 2013, the United States had an estimated 278 000 female lacrosse players, with half of those participating at the youth level. The effects of the sport's rapid growth on injury rates have yet to be determined. The purpose of this clinical review is to synthesize the available published data on injuries that have occurred in the sport of women's lacrosse. Of particular interest was the risk of injury based on the level of play and position. DATA SOURCES: A comprehensive literature search was performed in PubMed, High Wire Press, SPORTDiscus, Google Scholar, and Ovid using the keywords "Lacrosse Injuries," "Epidemiology Lacrosse Injuries," "Lacrosse Injury," "Lacrosse," and "Injury...
July 21, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28742129/treatment-outcomes-of-pre-surgical-infant-orthopedics-in-patients-with-non-syndromic-cleft-lip-and-or-palate-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#18
Hamid Reza Hosseini, Eleftherios G Kaklamanos, Athanasios E Athanasiou
BACKGROUND: Non-syndromic clefts lip and/or palate (CL/P) defects may have manifold significant and detrimental consequences for the affected individuals and their family environment. Although the use of pre-surgical infant orthopedics (PSIO) was introduced as a means to improve management and treatment outcomes, there still remains a controversy. OBJECTIVE: To investigate the effectiveness of PSIO in patients with non-syndromic CL/P and evaluate the quality of the available evidence...
2017: PloS One
https://www.readbyqxmd.com/read/28742084/systematic-tissue-specific-functional-annotation-of-the-human-genome-highlights-immune-related-dna-elements-for-late-onset-alzheimer-s-disease
#19
Qiongshi Lu, Ryan L Powles, Sarah Abdallah, Derek Ou, Qian Wang, Yiming Hu, Yisi Lu, Wei Liu, Boyang Li, Shubhabrata Mukherjee, Paul K Crane, Hongyu Zhao
Continuing efforts from large international consortia have made genome-wide epigenomic and transcriptomic annotation data publicly available for a variety of cell and tissue types. However, synthesis of these datasets into effective summary metrics to characterize the functional non-coding genome remains a challenge. Here, we present GenoSkyline-Plus, an extension of our previous work through integration of an expanded set of epigenomic and transcriptomic annotations to produce high-resolution, single tissue annotations...
July 24, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28742036/study-of-temporal-effects-on-subjective-video-quality-of-experience
#20
Christos G Bampis, Zhi Li, Anush K Moorthy, Ioannis Katsavounidis, Anne Aaron, Alan C Bovik
HTTP adaptive streaming is being increasingly deployed by network content providers such as Netflix and YouTube. By dividing video content into data chunks encoded at different bitrates, a client is able to request the appropriate bitrate for the segment to be played next based on the estimated network conditions. However, this can introduce a number of impairments, including compression artifacts and rebuffering events which can severely impact an end-user's quality of experience (QoE). We have recently created a new video quality database which simulates a typical video streaming application, using long video sequences and interesting Netflix content...
July 20, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
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