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https://www.readbyqxmd.com/read/28726642/coordinated-transcriptional-control-of-adipocyte-triglyceride-lipase-atgl-by-transcription-factors-sp1-and-ppar%C3%AE-during-adipocyte-differentiation
#1
Debasish Roy, Kenneth T Farabaugh, Jing Wu, Alyssa Charrier, Cynthia Smas, Maria Hatzoglou, Kavitha Thirumurugan, David A Buchner
The breakdown of stored fat deposits into its components is a highly regulated process that maintains plasma levels of free fatty acids to supply energy to cells. Insulin-mediated transcription of Atgl, the enzyme that mediates the rate-limiting step in lipolysis, is a key point of this regulation. In conditions such as obesity or insulin resistance, Atgl transcription is often misregulated, which can contribute to overall disease progression. The mechanisms by which Atgl is induced during adipogenesis are not fully understood...
July 18, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28723302/why-use-group-visits-for-opioid-use-disorder-treatment-in-primary-care-a-patient-centered-qualitative-study
#2
Randi Sokol, Chiara Albanese, Deviney Chaponis, Jessica Early, George Maxted, Diana Morrill, Grace Poirier, Fran Puopolo, Zev Schuman-Olivier
BACKGROUND: Primary care providers are well positioned to respond to the opioid crisis by providing buprenorphine/naloxone (B/N) through shared medical appointments (SMA). While quantitative research has been previously conducted on SMAs with B/N, we conducted a qualitative assessment from the patients' point of view, considering whether and how group visits provide value for patients. METHODS: Twenty-five participants with opioid use disorder (OUD) who were enrolled in a weekly B/N group visit at a family medicine clinic participated in either of two one-hour-long focus groups, which were conducted as actual group visits...
July 19, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28698935/the-anterior-smas-approach-for-facelifting-and-for-buccal-fat-pad-removal
#3
Malcolm D Paul
Having performed numerous varieties of SMAS advancement including: plication, resection, flap elevation with variable anterior deep dissection, the author has developed a direct approach to the mobile anterior SMAS which allows correction of midface descent, modest elevation of the modiolus, jawline correction, and, where indicated, direct access for buccal fat pad resection. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www...
July 11, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28695974/what-determine-the-quality-of-life-of-adult-patients-after-fontan-procedure
#4
Monika Smaś-Suska, Natalia Dłużniewska, Piotr Weryński, Jacek Pająk, Wojciech Płazak, Maria Olszowska, Piotr Podolec, Lidia Tomkiewicz-Pająk
BACKGROUND: Despite the low early mortality of Fontan procedures, Fontan patients are prone to various cardiac and extra-cardiac complications in the long term. This may influence patient perception of their health and outcome. The aim of the study was to assess the relationship of multi-organ complications and physical efficiency with self-reported health-related quality of life (QOL) in adult Fontan patients. METHODS: Quality of life was assessed with the Short Form-36 questionnaire...
July 11, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28586415/a-technique-using-the-suction-assisted-endoscope-sheath-to-transfer-smas-for-lip-augmentation
#5
Nina Shank, Pamela Tan, Kamran Khoobehi
No abstract text is available yet for this article.
June 6, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28574185/potential-of-the-high-photovoltaic-performance-non-fullerene-small-molecules
#6
Wanning Li, Huifeng Yao, Hao Zhang, Sunsun Li, Jianhui Hou
Over the past decades, fullerene derivatives have become the most successful electron acceptors in the organic solar cells (OSCs) and have achieved great progress, showing power conversion efficiencies (PCEs) of over 11%. However, fullerenes have some drawbacks such as weak absorption, limited energy-level tunability, and morphological instability. In addition, fullerene-based OSCs usually suffer from large energy losses of over 0.7 eV, which limits further improvement of the PCE. Recently, non-fullerene small molecules have emerged as promising electron acceptors in OSCs...
June 2, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28571075/erratum-rhytidoplasty-smas-imbrication-vector-comparison
#7
Fernando Pedroza, Rodrigo Iñiguez-Cuadra, Líder Chávez-Franco, Luis Fernando Pedroza, Juan Guillermo Erazo Cordoba
No abstract text is available yet for this article.
June 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28570465/shared-medical-appointments-for-adolescent-breast-reduction
#8
Tara L Braun, Matthew G Kaufman, Cristina Hernandez, Laura A Monson
Adolescents with macromastia face serious physical, emotional, and social burdens because of their large breast size. Studies have shown that reduction mammoplasty results in improvement in physical symptoms and quality of life for these patients. Shared medical appointments (SMAs), defined as individual patient-physician encounters that occur in a group setting, have been successfully applied to clinics for adult patients seeking breast reduction for this condition. We decided to apply the SMA model to our clinic for preoperative evaluation of adolescent patients with macromastia...
May 31, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28549471/the-shared-health-appointments-and-reciprocal-enhanced-support-shares-study-study-protocol-for-a-randomized-trial
#9
Michele Heisler, Jennifer Burgess, Jeffrey Cass, John F Chardos, Alexander B Guirguis, Sean M Jeffery, Lorrie A Strohecker, Adam S Tremblay, Wen-Chih Wu, Donna M Zulman
BACKGROUND: Diabetes shared medical appointments (SMAs) and reciprocal peer support programs have been found in efficacy trials to help adults with diabetes improve their self-management and achieve short-term gains in clinical and patient-centered outcomes. In order to translate this evidence to system-level interventions, there is a need for large-scale, pragmatic trials that examine the effectiveness, implementation, and costs of SMAs and reciprocal peer support across diverse settings...
May 26, 2017: Trials
https://www.readbyqxmd.com/read/28548010/initial-experience-with-the-6-f-and-8-f-indigo-thrombectomy-system-for-acute-renovisceral-occlusive-events
#10
Theodosios Bisdas, Konstantinos Stavroulakis, Efthymios Beropoulis, Arne Schwindt, Arne Stachmann, Martin Austermann, Giovanni Torsello
PURPOSE: To examine the safety and effectiveness of the new large-bore Indigo thrombectomy catheters to treat patients with acute renovisceral occlusion without the need of thrombolytic agents. METHODS: Between November 2015 and 2016, 7 consecutive patients (mean age 65±5 years; 5 men) with acute renovisceral artery occlusion were treated with the new large-bore (6-F and 8-F) vacuum-assisted thrombectomy catheters. The occluded vessels were 6 renal arteries and 3 superior mesenteric arteries (SMAs); 5 of the 9 thromboses were in bridging stent-grafts associated with branched endografts...
May 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28546786/the-association-between-higher-nurse-staffing-standards-in-the-fee-schedules-and-the-geographic-distribution-of-hospital-nurses-a-cross-sectional-study-using-nationwide-administrative-data
#11
Noriko Morioka, Jun Tomio, Toshikazu Seto, Yasuki Kobayashi
BACKGROUND: In Japan, the revision of the fee schedules in 2006 introduced a new category of general care ward for more advanced care, with a higher staffing standard, a patient-to-nurse ratio of 7:1. Previous studies have suggested that these changes worsened inequalities in the geographic distribution of nurses, but there have been few quantitative studies evaluating this effect. This study aimed to investigate the association between the distribution of 7:1 beds and the geographic distribution of hospital nursing staffs...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28490801/dendritic-cells-provide-a-therapeutic-target-for-synthetic-small-molecule-analogues-of-the-parasitic-worm-product-es-62
#12
Felicity E Lumb, James Doonan, Kara S Bell, Miguel A Pineda, Marlene Corbet, Colin J Suckling, Margaret M Harnett, William Harnett
ES-62, a glycoprotein secreted by the parasitic filarial nematode Acanthocheilonema viteae, subverts host immune responses towards anti-inflammatory phenotypes by virtue of covalently attached phosphorylcholine (PC). The PC dictates that ES-62 exhibits protection in murine models of inflammatory disease and hence a library of drug-like PC-based small molecule analogues (SMAs) was synthesised. Four sulfone-containing SMAs termed 11a, 11e, 11i and 12b were found to reduce mouse bone marrow-derived dendritic cell (DC) pathogen-associated molecular pattern (PAMP)-induced pro-inflammatory cytokine production, inhibit NF-κB p65 activation, and suppress LPS-induced up-regulation of CD40 and CD86...
May 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28481073/-superior-mesenteric-artery-syndrome-a-case-report-and-review-of-the-literature
#13
A Pastén González, A Muñoz Araneda, A Peirano Bastías, S Rojas Castro, V Henríquez Alessandrini
INTRODUCTION: Superior mesenteric artery syndrome (SMAS) or Wilkie syndrome is a rare disease in the pediatric population. Although their causes are generally well known, the clinic is often subtle, so reaching a diagnosis can be difficult. There are medical and surgical treatment options, which depend on each patient. CLINICAL CASE: Our study shows an atypical case of SAMS, which debuted in a 13-year-old boy without previous diseases, and without a history of risk factors for this pathology...
October 10, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/28442711/temperature-dependent-fracture-properties-of-shape-memory-alloys-novel-findings-and-a-comprehensive-model
#14
Carmine Maletta, Emanuele Sgambitterra, Fabrizio Niccoli
Temperature dependent fracture properties of NiTi-based Shape Memory Alloys (SMAs), within the pseudoelastic regime, were analyzed. In particular, the effective Stress Intensity Factor (SIF) was estimated, at different values of the testing temperature, by a fitting of the William's expansion series, based on Digital Image Correlation (DIC) measurements. It was found that temperature plays an important role on SIF and on critical fast fracture conditions. As a consequence, Linear Elastic Fracture Mechanics (LEFM) approaches are not suitable to predict fracture properties of SMAs, as they do not consider the effects of temperature...
December 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28372067/design-framework-for-spherical-microphone-and-loudspeaker-arrays-in-a-multiple-input-multiple-output-system
#15
Hai Morgenstern, Boaz Rafaely, Markus Noisternig
Spherical microphone arrays (SMAs) and spherical loudspeaker arrays (SLAs) facilitate the study of room acoustics due to the three-dimensional analysis they provide. More recently, systems that combine both arrays, referred to as multiple-input multiple-output (MIMO) systems, have been proposed due to the added spatial diversity they facilitate. The literature provides frameworks for designing SMAs and SLAs separately, including error analysis from which the operating frequency range (OFR) of an array is defined...
March 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28333197/bilayered-structure-of-the-superficial-facial-fascia
#16
Hyun Gu Kang, Kwan-Hyun Youn, In-Beom Kim, Yong Seok Nam
Background: The superficial facial fascia comprises the superficial musculoaponeurotic system (SMAS) and the temporoparietal fascia (TPF) and is regarded as a continuous monolayer. However, some evidence indicates that the superficial facial fascia consists of 2 layers in specific areas. Objectives: The authors evaluated the superficial facial fascia for bilayered regions. Methods: Twenty fresh cadavers (40 hemifaces) were dissected to observe the superficial facial fascia...
June 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28332864/effect-of-density-gradient-centrifugation-on-reactive-oxygen-species-in-human-semen
#17
Teppei Takeshima, Yasushi Yumura, Shinnosuke Kuroda, Takashi Kawahara, Hiroji Uemura, Akira Iwasaki
Density gradient centrifugation can separate motile sperm from immotile sperm and other cells for assisted reproduction, but may also remove antioxidants from seminal plasma, resulting in oxidative stress. Therefore, we investigated reactive oxygen species (ROS) concentrations and distribution in semen before and after density gradient centrifugation. We assessed semen volume, sperm concentration, sperm motility, and ROS levels before and after density gradient centrifugation (300 x g for 20 minutes) in 143 semen samples from 118 patients...
June 2017: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/28292766/examining-sufficiency-and-equity-in-the-geographic-distribution-of-physicians-in-japan-a-longitudinal-study
#18
Koji Hara, Tetsuya Otsubo, Susumu Kunisawa, Yuichi Imanaka
OBJECTIVES: The objective of this study was to longitudinally examine the geographic distribution of physicians in Japan with adjustment for healthcare demand according to changes in population age structure. METHODS: We examined trends in the number of physicians per 100 000 population in Japan's secondary medical areas (SMAs) from 2000 to 2014. Healthcare demand was adjusted using health expenditure per capita. Trends in the Gini coefficient and the number of SMAs with a low physician supply were analysed...
March 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/28280679/asian-facial-rejuvenation-by-extended-smas-facelift-technique
#19
Joo Heon Lee
Supplemental Digital Content is available in the text.
February 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28275450/factors-associated-with-clinic-escorts-in-peer-led-hiv-prevention-interventions-for-men-who-have-sex-with-men-msm-in-sri-lanka
#20
EDITORIAL
M Suchira Suranga, D A Karawita, Smas Bandara, Rmdk Rajakaruna
BACKGROUND: Sri Lanka has recently completed an HIV prevention project for most-at-risk populations (MARP) under the Global Fund. The intervention includes delivery of a HIV prevention package (HPP) to men who have sex with men (MSM) that includes provision of: (1) knowledge about sexually transmitted infections (STI); (2) HIV knowledge; (3) MSM-tailored leaflets; (4) condom/dildo demonstration; (5) provision of condoms; and (6) clinic escorts. MSM who received services 1-5 in the HPP are defined as 'reached'...
November 28, 2016: Journal of Virus Eradication
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