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https://www.readbyqxmd.com/read/28414996/a-case-of-multiple-synchronous-quadruple-cancers-of-the-stomach-sigmoid-colon-rectum-and-pancreas
#1
Atsushi Nanashima, Tetsuro Tominaga, Takashi Nonaka, Kouki Wakata, Masaki Kunizaki, Shuichi Tobinaga, Yorihisa Sumida, Shigekazu Hidaka, Naoe Kinoshita, Terumitsu Sawai, Takeshi Nagayasu
INTRODUCTION: Multiple primary neoplasms are relatively rare, but their incidence has increased because of aging and improvements in diagnostic imaging. PRESENTATION OF CASE: A 67-year-old man presented with epigastric pain. On upper gastrointestinal endoscopy, an ulcer was seen at the gastric angle, and biopsy showed moderately differentiated adenocarcinoma (AC). Colonoscopy demonstrated a 15-mm lesion in the sigmoid colon and a submucosal lesion in the lower rectum...
April 2, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28411889/factibility-and-security-study-of-the-pics-af%C3%A2-plug-for-the-treatment-of-cryptoglandular-anal-fistula
#2
Fernando de la Portilla, María Luisa Reyes-Díaz, María Victoría Maestre, Rosa María Jiménez-Rodríguez, Ana María García-Cabrera, José M Díaz-Pavón, Jorge Manuel Vázquez-Monchul, Juan Antonio Villanueva
INTRODUCTION: The PICS-AF™ (Curaseal Inc.) device is a new plug made of collagen that has a retention system in the internal orifice. This pilot study was designed to assess both the feasibility and safety of this plug in the treatment of trans-sphincteric anal fístulas. METHODS: A total of 44 patients (34 men), with a mean age of 54.68±7.3, with trans-sphincteric anal fístulas were included in the study; 34 of them were analyzed. All patients were examined according to a strict preoperative protocol and until 6 months after surgery...
April 12, 2017: Cirugía Española
https://www.readbyqxmd.com/read/28359279/low-volume-versus-high-volume-initiated-trans-anal-irrigation-therapy-in-adults-with-chronic-constipation-study-protocol-for-a-randomised-controlled-trial
#3
Christopher Emmett, Helen Close, James Mason, Shiva Taheri, Natasha Stevens, Sandra Eldridge, Christine Norton, Charles Knowles, Yan Yiannakou
BACKGROUND: Constipation is common in adults and up to 20% of the population report this symptom. Chronic constipation (CC), usually defined as more than 6 months of symptoms, is less common but results in 0.5 million UK GP consultations per annum. The effect of symptoms on measured quality of life (QOL) is significant, and CC consumes significant health care resources. In the UK, it is estimated that 10% of district nursing time is spent on constipation. Trans-anal irrigation therapy has become a widely used treatment despite a lack of robust efficacy data to support its use...
March 31, 2017: Trials
https://www.readbyqxmd.com/read/28290968/management-of-post-traumatic-rectovesical-rectourethral-fistulas-case-series-of-complicated-injuries-in-wounded-warriors-and-review-of-the-literature
#4
Walter B Kucera, James R Jezior, James E Duncan
INTRODUCTION: Penetrating injuries to the pelvis and perineum can result in fistulas between the rectum and lower urinary tract. These injuries are often complicated, which creates challenges for successful repair. Operative strategies may include initial fecal and/or urinary diversion combined with an eventual trans-perineal, trans-anal, or posterior/transrectal approach, but the selected approach should be guided by precise anatomic localization of the injury. We aim to discuss different possible repair strategies as well as the relevant data surrounding gastrointestinal-genitourinary (GI-GU) fistula management...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28273604/mucocele-complicating-stapled-hemorrhoidopexy
#5
Asia Grapsi, Alessandro Sturiale, Bernardina Fabiani, Gabriele Naldini
INTRODUCTION: Stapled hemorrhoidopexy is a safe and effective treatment for circumferential hemorrhoidal prolapse. The overall rate of complications ranges from 12,7% to 36,4% and the surgeon should be aware about their early identification and adequate treatment. PRESENTATION OF CASE: Female patient, 57 years was treated with stapled hemorrhoidopexy. Two years after surgery she reported to our center the occurrence of perineal discomfort, anal spasm and tenesmus...
February 20, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28236144/hiv-prevalence-sexual-partners-sexual-behavior-and-hiv-acquisition-risk-among-trans-men-san-francisco-2014
#6
Willi McFarland, Erin C Wilson, Henry F Raymond
We surveyed 122 trans men using a hybrid sampling method that included randomly selected physical and online venues and peer referral to measure HIV prevalence and risk behaviors. HIV prevalence was 0% (one-sided 97.5% confidence interval 0-3.3%). Of 366 partnerships described, 44.8% were with cisgender women, 23.8% with cisgender men, 20.8% with trans men, and 10.7% with trans women. Condomless receptive anal and front hole/vaginal sex averaged one to three episodes per six months. HIV prevalence in trans men is likely closer to heterosexual cisgender men and women in San Francisco than trans women or MSM...
February 24, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28127423/comparison-of-trans-anal-endoscopic-operation-and-trans-anal-excision-of-rectal-tumors
#7
Mahdi Hussain Al Bandar, Yoon Dae Han, Syed Asim Razvi, Min Soo Cho, Hyuk Hur, Byung Soh Min, Kang Young Lee, Nam Kyu Kim
BACKGROUND: Trans-anal endoscopic operation (TEO) has developed to facilitate proper tumor location and ensure excision safely. METHODS: We reviewed 92 patients enrolled in our database between 2006 and 2014 who were diagnosed with early rectal tumors and who underwent conventional trans-anal excision (TAE) or TEO. Clinical data were collected prospectively to compare safety and feasibility between two techniques. RESULTS: Ninety-two patients underwent trans-anal local excision for lower rectal tumors...
February 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28073875/unexpected-complication-after-radical-inguinal-orchidectomy-trans-sphincteric-anoscrotal-fistula
#8
Amit Patel, Chris Gillespie, Anthony J Kiosoglous
Anoscrotal fistula is an extremely rare condition involving an epithelialised tract between the anal canal and scrotal wall. It is more commonly seen as a congenital phenomenon in the paediatric population, and has not previously been described in the literature in adults. We present the case of a man aged 52 years who developed a complex anoscrotal fistula after a radical inguinal orchidectomy for an intratesticular seminoma. A postsurgical wound-site infection developed into a chronically discharging wound refractory to antibiotic treatment prompting further investigation...
January 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/27865742/internal-rectal-prolapse-definition-assessment-and-management-in-2016
#9
L Cariou de Vergie, A Venara, E Duchalais, E Frampas, P A Lehur
Internal rectal prolapse (IRP) is a well-recognized pelvic floor disorder mainly seen during defecatory straining. The symptomatic expression of IRP is complex, encompassing fecal continence (56%) and/or evacuation disorders (85%). IRP cannot be characterized easily by clinical examination alone and the emergence of dynamic defecography (especially MRI) has allowed a better comprehension of its pathophysiology and led to the proposition of a severity score (Oxford score) that can guide management. Decision for surgical management should be multidisciplinary, discussed after a complete work-up, and only after medical treatment has failed...
November 16, 2016: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/27861237/brief-report-psychosocial-predictors-of-engagement-in-sexual-risk-behavior-among-trans-female-youth-aged-16-24-years-in-san-francisco
#10
Caitlin M Turner, Glenn-Milo Santos, Sean Arayasirikul, Erin C Wilson
BACKGROUND: Trans*female youth (TFY) carry a disproportionate burden of HIV. Few longitudinal studies have analyzed both proximal and upstream predictors of changes in HIV-related risk behaviors for TFY. The aim of the present analysis was to identify psychosocial predictors of changes in sexual risk behavior over time for TFY in the San Francisco Bay Area. METHODS: Data come from the SHINE cohort study conducted at the San Francisco Department of Public Health from 2012 to 2014 (n = 263)...
March 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27830038/advances-in-minimally-invasive-neonatal-colorectal-surgery
#11
REVIEW
Ashwath S Bandi, Catherine J Bradshaw, Stefano Giuliani
Over the last two decades, advances in laparoscopic surgery and minimally invasive techniques have transformed the operative management of neonatal colorectal surgery for conditions such as anorectal malformations (ARMs) and Hirschsprung's disease. Evolution of surgical care has mainly occurred due to the use of laparoscopy, as opposed to a laparotomy, for intra-abdominal procedures and the development of trans-anal techniques. This review describes these advances and outlines the main minimally invasive techniques currently used for management of ARMs and Hirschsprung's disease...
October 27, 2016: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27778256/comparative-study-between-trans-perineal-repair-with-or-without-limited-internal-sphincterotomy-in-the-treatment-of-type-i-anterior-rectocele-a-randomized-controlled-trial
#12
Mohamed Youssef, Sameh Hany Emile, Waleed Thabet, Hossam Ayman Elfeki, Alaa Magdy, Waleed Omar, Wael Khafagy, Mohamed Farid
BACKGROUND AND AIM: Two types of rectocele exist; type I is characterized by relatively high resting anal pressures, whereas type II has lower resting anal pressures with associated pelvic organ prolapse. We compared trans-perineal repair (TPR) of rectocele with or without limited internal sphincterotomy (LIS) in the treatment of type I anterior rectocele. PATIENTS AND INTERVENTIONS: Consecutive patients with anterior rectocele were evaluated for inclusion. Sixty-two female patients with type I anterior rectocele were randomized and equally allocated to receive TPR alone (group I) or TPR with LIS (group II)...
October 24, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27704667/quality-of-life-following-fistulotomy-short-term-follow-up
#13
H A Owen, G N Buchanan, A Schizas, A Emmanuel, R Cohen, A B Williams
INTRODUCTION: Anal fistula causes pain, discharge of pus and blood. Fistulotomy has the highest success, however, can risk continence; treatment balances cure with continence. This study assessed the impact of fistulotomy on Quality Of Life (QOL) and continence. METHODS: Patients selected for fistulotomy prospectively completed St Mark's Continence Score (full incontinence = 24) and Short Form - 36 questionnaires pre-operatively at two institutions with an interest in anal fistula, and reassessed 3 months post-operatively...
October 5, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27631775/acute-adverse-events-and-postoperative-complications-in-a-randomized-trial-of-preoperative-short-course-radiotherapy-versus-long-course-chemoradiotherapy-for-t3-adenocarcinoma-of-the-rectum-trans-tasman-radiation-oncology-group-trial-trog-01-04
#14
Nabila Ansari, Michael J Solomon, Richard J Fisher, John Mackay, Bryan Burmeister, Stephen Ackland, Alexander Heriot, David Joseph, Sue-Anne McLachlan, Bev McClure, Samuel Y Ngan
OBJECTIVE: To compare acute adverse events (AE) and postoperative complication rates in a randomized trial of short-course (SC) versus long-course (LC) preoperative radiotherapy. BACKGROUND: Evidence demonstrates that adding neoadjuvant radiotherapy to surgery offers better local control in the management of rectal cancer. With both SC and LC therapy there is a potential for acute treatment-related toxicity and increased patient morbidity. METHODS: Eligible patients had clinical-stage T3 rectal adenocarcinoma within 12 cm of the anal verge with no evidence of metastasis...
May 2017: Annals of Surgery
https://www.readbyqxmd.com/read/27531461/awareness-and-willingness-to-use-pre-exposure-prophylaxis-prep-among-men-who-have-sex-with-men-and-transgender-women-in-brazil
#15
Brenda Hoagland, Raquel B De Boni, Ronaldo I Moreira, José Valdez Madruga, Esper G Kallas, Silvia Pereira Goulart, Natalia Cerqueira, Thiago S Torres, Paula M Luz, Nilo Martinez Fernandes, Albert Y Liu, Beatriz Grinsztejn, Valdilea G Veloso
Antiretroviral pre-exposure prophylaxis (PrEP) is recommended to prevent HIV infection among high-risk men who have sex with men (MSM) though not available in Brazil where the HIV epidemic persists unabated in this group. This cross-sectional study describes PrEP awareness and willingness and associated factors among MSM and transvestite/transgender women (trans women) pre-screened for the PrEP Brasil study. Awareness was reported by 61.3 % of the participants and was associated with age, education, site, study period and prior HIV testing...
August 17, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27506355/direct-glycan-structure-determination-of-intact-n-linked-glycopeptides-by-low-energy-collision-induced-dissociation-tandem-mass-spectrometry-and-predicted-spectral-library-searching
#16
Pei-Jing Pai, Yingwei Hu, Henry Lam
Intact glycopeptide MS analysis to reveal site-specific protein glycosylation is an important frontier of proteomics. However, computational tools for analyzing MS/MS spectra of intact glycopeptides are still limited and not well-integrated into existing workflows. In this work, a new computational tool which combines the spectral library building/searching tool, SpectraST (Lam et al. Nat. Methods2008, 5, 873-875), and the glycopeptide fragmentation prediction tool, MassAnalyzer (Zhang et al. Anal. Chem.2010, 82, 10194-10202) for intact glycopeptide analysis has been developed...
August 31, 2016: Analytica Chimica Acta
https://www.readbyqxmd.com/read/27492711/double-balloon-assisted-trans-anal-ercp-in-a-patient-with-roux-en-y-choledochojejunostomy
#17
Rintaro Hashimoto, Tomoki Matsuda, Hayato Aoki, Toru Okuzono, Masato Nakahori
No abstract text is available yet for this article.
August 1, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27431468/hiv-prevalence-and-demographic-determinants-of-condomless-receptive-anal-intercourse-among-trans-feminine-individuals-in-beirut-lebanon
#18
Rachel L Kaplan, Justine McGowan, Glenn J Wagner
INTRODUCTION: Growing evidence suggests increased HIV incidence in the Middle East and North Africa among "key populations." To date, epidemiological data have not accurately included and measured HIV prevalence and risk among trans feminine individuals in the region. Through the lens of the Gender Affirmation Framework, we assessed demographic correlates of risk behaviour and the prevalence of HIV among trans feminine individuals in Lebanon. METHODS: Long-chain referral sampling was used to recruit 53 participants for completion of a behavioural survey and optional free rapid HIV tests...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/27431467/types-of-social-support-and-parental-acceptance-among-transfemale-youth-and-their-impact-on-mental-health-sexual-debut-history-of-sex-work-and-condomless-anal-intercourse
#19
Victory Le, Sean Arayasirikul, Yea-Hung Chen, Harry Jin, Erin C Wilson
INTRODUCTION: Transfemale youth (TFY) are an underserved and understudied population at risk for numerous poor physical and mental health outcomes, most notably HIV. Research suggests that parental acceptance and social support may serve as protective factors against HIV and other risks for TFY; however, it is unclear whether TFY receive primary social support from parents with or without parental acceptance of their gender identity. This study examines differences in parental acceptance, mental health and the HIV risk factors of history of sex work, age at sexual debut and engagement in condomless anal intercourse between TFY with two types of primary social support - non-parental primary social support (NPPSS) and parental primary social support (PPSS)...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/27379633/development-of-neural-activity-in-the-enteric-nervous-system-similarities-and-differences-to-other-parts-of-the-nervous-system
#20
Marlene M Hao
All the neurons and glia of the enteric nervous system (ENS) arise from neural crest-derived cells that migrate into the gastrointestinal (GI) tract during development (Yntema and Hammond 1954; Le Douarin and Teillet 1973). Most of the ENS originates from vagal neural crest cells (NCCs), which arise from the caudal hindbrain region of the neural tube, adjacent to somites 1-7. In the developing mouse, vagal NCCs migrate into the developing oesophagus and stomach at embryonic day (E)9.5, enter the small intestine at E10...
2016: Advances in Experimental Medicine and Biology
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