keyword
MENU ▼
Read by QxMD icon Read
search

watch and wait

keyword
https://www.readbyqxmd.com/read/28545508/open-label-versus-double-blind-placebo-treatment-in-irritable-bowel-syndrome-study-protocol-for-a-randomized-controlled-trial
#1
Sarah Ballou, Ted J Kaptchuk, William Hirsch, Judy Nee, Johanna Iturrino, Kathryn T Hall, John M Kelley, Vivian Cheng, Irving Kirsch, Eric Jacobson, Lisa Conboy, Anthony Lembo, Roger B Davis
BACKGROUND: Placebo medications, by definition, are composed of inactive ingredients that have no physiological effect on symptoms. Nonetheless, administration of placebo in randomized controlled trials (RCTs) and in clinical settings has been demonstrated to have significant impact on many physical and psychological complaints. Until recently, conventional wisdom has suggested that patients must believe that placebo pills actually contain (or, at least, might possibly contain) active medication in order to elicit a response to placebo...
May 25, 2017: Trials
https://www.readbyqxmd.com/read/28543927/the-waiting-period-following-cavotricuspid-isthmus-ablation-opportunity-for-watchful-observation-or-a-waste-of-time
#2
EDITORIAL
Advay G Bhatt, Suneet Mittal
No abstract text is available yet for this article.
May 24, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28537787/the-feasibility-of-short-course-radiotherapy-in-a-watch-and-wait-policy-for-rectal-cancer
#3
K Bujko, L Pietrzak, M Partycki, M Szczepkowski, L Wyrwicz, M Rupiński, A Rutkowski, A Mróz
No abstract text is available yet for this article.
May 24, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28521677/molluscum-contagiosum-an-update
#4
Alexander Kc Leung, Benjamin Barankin, Kam Lun Hon
BACKGROUND: Molluscum contagiosum is a viral cutaneous infection in childhood that occurs worldwide. Physicians should familiarize themselves with this common condition. OBJECTIVE: To review in depth the epidemiology, pathophysiology, clinical manifestations, complications and, in particular, treatment of molluscum contagiosum. METHODS: A PubMed search was completed in Clinical Queries using the key term "molluscum contagiosum". Patents were searched using the key term "molluscum contagiosum" from www...
May 17, 2017: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28506950/fertility-sparing-approach-as-the-standard-of-care-in-young-patients-with-immature-teratomas
#5
Christos Iavazzo, George Vorgias, Paraskevi Evangelia Iavazzo, Ioannis D Gkegkes
Immature teratomas are quite rare tumors arising in young women. They are usually diagnosed in early stage and grade and have a good prognosis. In these young patients, fertility-sparing management is suggested as the standard of care. Bilateral immature teratoma is a rare condition with an incidence of 10%, with a five-year survival rate of 80%. The majority of patients received fertility-sparing treatment followed by adjuvant chemotherapy in 78%. Older age, advanced stage, and high grade are negative prognostic factors...
March 15, 2017: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/28501249/new-strategies-in-rectal-cancer
#6
REVIEW
Guilherme Pagin São Julião, Angelita Habr-Gama, Bruna Borba Vailati, Sergio Eduardo Alonso Araujo, Laura Melina Fernandez, Rodrigo Oliva Perez
In recent years, our understanding of rectal cancer has improved, including how locally advanced disease responds to chemotherapy and radiation. This has led to new innovations and advances in the treatment of rectal cancer, which includes organ-preserving strategies for responsive disease, and minimally invasive approaces for the performance of total mesorectal excision/protectomyh for persistently advanced disease. This article discusses new strategies for rectal cancer therapy, including Watch and Wait, local excision, minimally invasive proctectomy, and transanal total mesorectal excision particularly in the setting of preoperative multimodality treatment...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28494599/a-combined-approach-with-passive-and-active-repositioning-of-a-traumatically-intruded-immature-permanent-incisor
#7
H J Kim, Y I Kim, K S Min
BACKGROUND: Severe damage to the tooth, periodontal ligament, and pulpal tissue often occurs with intrusive luxation, and outcomes are quite unpredictable because of the variable ways in which the injury may occur, which influences both the choice of treatment and prognosis. CASE REPORT: This case presents a novel method for the management of an intruded permanent maxillary central incisor with an immature apex. At first, watchful waiting for spontaneous re-eruption was the chosen treatment option...
March 2017: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28480341/updated-clinical-results-of-active-surveillance-of-very-low-risk-prostate-cancer-in-korean-men-8-years-of-follow-up
#8
Ji Yong Ha, Teak Jun Shin, Wonho Jung, Byung Hoon Kim, Choal Hee Park, Chun Il Kim
PURPOSE: Update and reanalysis of our experience of active surveillance (AS) for prostate cancer (PCa) in Korea. MATERIALS AND METHODS: A prospective, single-arm, cohort study was initiated in January 2008. Patients were selected according to the following criteria: Gleason sum ≤6 with single positive core with ≤30% core involvement, clinical stage≤T1c, prostate-specific antigen (PSA)≤10 ng/mL, and negative magnetic resonance imaging (MRI) results. Follow-up was by PSA measurement every 6 months, prostate biopsies at 1 year and then every 2-3 years, and MRI every year...
May 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28479860/rituximab-in-the-treatment-of-follicular-lymphoma-the-future-of-biosimilars-in-the-evolving-therapeutic-landscape
#9
REVIEW
Janakiraman Subramanian, Jamie Cavenagh, Bhardwaj Desai, Ira Jacobs
Follicular lymphoma (FL) is the second most common type of non-Hodgkin's lymphoma. FL is an incurable disease with treatment options ranging from a "watch-and-wait" approach to localized therapy with radiation or systemic therapy with rituximab in combination with chemotherapy regimens. This review summarizes the role of rituximab across the spectrum of FL treatment and the evolving therapeutic landscape with the emergence of novel agents currently in clinical development. Despite the prospect of new agents on the horizon, it is widely accepted that rituximab will remain as the cornerstone of therapy because of its established long-term efficacy...
2017: Cancer Management and Research
https://www.readbyqxmd.com/read/28479373/what-is-there-to-learn-for-watch-and-wait-in-rectal-cancer
#10
Maxime J M van der Valk, Denise E Hilling, Cornelis J H van de Velde
No abstract text is available yet for this article.
May 4, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28479372/a-watch-and-wait-approach-for-locally-advanced-rectal-cancer-after-a-clinical-complete-response-following-neoadjuvant-chemoradiation-a-systematic-review-and-meta-analysis
#11
Fahima Dossa, Tyler R Chesney, Sergio A Acuna, Nancy N Baxter
BACKGROUND: A watch-and-wait approach for patients with clinical complete response to neoadjuvant chemoradiation could avoid the morbidity of conventional surgery for rectal cancer. However, the safety of this approach is unclear. We synthesised the evidence for watch-and-wait as a treatment for rectal cancer. METHODS: We systematically searched MEDLINE, Embase, and the grey literature (up to June 28, 2016) for studies of patients with rectal adenocarcinoma managed by watch-and-wait after complete clinical response to neoadjuvant chemoradiation...
May 4, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28476941/systemic-chemotherapy-as-salvage-treatment-for-locally-advanced-rectal-cancer-patients-who-fail-to-respond-to-standard-neoadjuvant-chemoradiotherapy
#12
Francesco Sclafani, Gina Brown, David Cunningham, Sheela Rao, Paris Tekkis, Diana Tait, Federica Morano, Chiara Baratelli, Eleftheria Kalaitzaki, Shahnawaz Rasheed, David Watkins, Naureen Starling, Andrew Wotherspoon, Ian Chau
BACKGROUND: The potential of chemotherapy as salvage treatment after failure of neoadjuvant chemoradiotherapy for locally advanced rectal cancer (LARC) has never been explored. We conducted a single-center, retrospective analysis to address this question. PATIENTS AND METHODS: Patients with newly diagnosed LARC who were inoperable or candidates for extensive (i.e., beyond total mesorectal excision [TME]) surgery after long-course chemoradiotherapy and who received salvage chemotherapy were included...
May 5, 2017: Oncologist
https://www.readbyqxmd.com/read/28475680/surgical-resection-versus-watchful-waiting-in-low-grade-gliomas
#13
A S Jakola, A J Skjulsvik, K S Myrmel, K Sjåvik, G Unsgård, S H Torp, K Aaberg, T Berg, H Y Dai, K Johnsen, R Kloster, O Solheim
Background: HASH(0x33835a0) Material and methods: HASH(0x33b9998) Results: HASH(0x32e9808) Conclusion: HASH(0x32c4830)
May 5, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28471976/comparative-effectiveness-of-prostate-cancer-treatments-for-patient-centered-outcomes-a-systematic-review-and-meta-analysis-prisma-compliant
#14
Ravishankar Jayadevappa, Sumedha Chhatre, Yu-Ning Wong, Marsha N Wittink, Ratna Cook, Knashawn H Morales, Neha Vapiwala, Diane K Newman, Thomas Guzzo, Alan J Wein, Stanley B Malkowicz, David I Lee, Jerome S Schwartz, Joseph J Gallo
BACKGROUND: In the context of prostate cancer (PCa) characterized by the multiple alternative treatment strategies, comparative effectiveness analysis is essential for informed decision-making. We analyzed the comparative effectiveness of PCa treatments through systematic review and meta-analysis with a focus on outcomes that matter most to newly diagnosed localized PCa patients. METHODS: We performed a systematic review of literature published in English from 1995 to October 2016...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28470658/-free-floating-intraocular-cysts
#15
Jens Ulrich Werner, Gerhard K Lang, Christian Enders
Background Free-floating intraocular cysts may be found in the anterior chamber (FZV) and the vitreous (FZG). The first description of a cyst was 150 years ago, and they are considered to be ocular rarities. Materials and Methods The actual knowledge about FZV and FZG is shown on the basis of two exemplary patients. Results and Discussion Patient 1 had a FZV as an incidental finding which had a smooth surface, a slight pigmentation and was translucent. The ultrasound biomicroscopy revealed an echo-free interior space...
May 3, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28468768/management-of-endocrine-disease-present-and-future-perspectives-for-medical-therapy-of-non-functioning-pituitary-adenomas
#16
Yona Greenman
In contrast to the clear indication for surgical treatment in symptomatic patients with clinically nonfunctioning pituitary adenomas (NFPA), there are no randomized controlled studies comparing therapeutic strategies such as watchful waiting, irradiation, or medical therapy for the management of NFPA after surgery. Further, no medical therapy is currently approved for the treatment of NFPA. In this review, we summarize accumulating data on medications currently approved for secreting pituitary adenomas, used off-label in patients with NFPA...
May 3, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28462648/predicting-response-to-neoadjuvant-chemoradiotherapy-in-locally-advanced-rectal-cancer-with-serum-biomarkers
#17
T L Clarke, D A White, M E Osborne, A M Shaw, N J Smart, I R Daniels
Introduction The aim of this study was to identify patient factors including serum biomarkers that may predict response to neoadjuvant chemoradiotherapy (CRT) in patients with locally advanced rectal cancer staged on magnetic resonance imaging. Prediction of response may be helpful when selecting patients for a non-operative programme. Methods A retrospective review was carried out of patients undergoing neoadjuvant CRT for rectal cancer, conducted at the Royal Devon and Exeter Hospital. All patients were managed through the multidisciplinary team...
May 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28443142/effects-of-androgen-deprivation-therapy-on-hypercoagulability-in-prostate-cancer-patients-a-prospective-longitudinal-study
#18
Harmanpreet Kaur, D Robert Siemens, Angela Black, Sylvia Robb, Spencer Barr, Charles H Graham, Maha Othman
INTRODUCTION: Androgen-deprivation therapy (ADT) is the mainstay of systemic therapy for advanced prostate cancer (PCa), but has significant adverse effects, including increasing concern for cardiovascular (CV) and thromboembolic (TE) complications. This study carefully investigates any relationship between ADT use and hypercoagulability as a possible mechanism of these adverse effects. METHODS: We performed a prospective, longitudinal study in a cohort of patients with advanced PCa initiating ADT (n=18)...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28440523/-outcome-of-watch-and-wait-strategy-or-organ-preservation-for-rectal-cancer-following-neoadjuvant-chemoradiotherapy-report-of-35-cases-from-a-single-cancer-center
#19
Aiwen Wu, Lin Wang, Changzheng Du, Yifan Peng, Yunfeng Yao, Jun Zhao, Tiancheng Zhan, Yong Cai, Yongheng Li, Yingshi Sun, Jiafu Ji
OBJECTIVE: To investigate the safety and efficacy of organ preservation surgery or "watch and wait" strategy for rectal cancer patients who are evaluated as clinical complete response(cCR) or near-cCR following neoadjuvant chemoradiotherapy (nCRT). METHOD: From March 2011 to June 2016, 35 patients with mid-low rectal cancers who were diagnosed as cCR or near-cCR following nCRT underwent organ preservation surgery with local excision or surveillance following "watch and wait" strategy in the Peking University Cancer Hospital...
April 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28439490/watch-and-wait-policy-in-advanced-neuroendocrine-tumors-what-does-it-mean
#20
EDITORIAL
Nicola Fazio
Neuroendocrine neoplasms (NENs) are a group of rare and heterogeneous malignancies, which can develop in various organs. The clinical course of NENs is quite heterogeneous, with different spontaneous growth rates after diagnosis, and different degrees of sensitivity to the same therapy even when they have similar characteristics. Watch and wait (W and W), is a term coined to indicate observation being conducted to assess the evolution of the tumor without administering any anti-tumor therapy. It has been applied to NENs since in extremely rare cases they tend to remain stable for a long time...
April 10, 2017: World Journal of Clinical Oncology
keyword
keyword
99047
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"