keyword
MENU ▼
Read by QxMD icon Read
search

watch and wait

keyword
https://www.readbyqxmd.com/read/28635333/molecular-biomarkers-to-guide-precision-medicine-in-localized-prostate-cancer
#1
Minke Smits, Niven Mehra, Michiel Sedelaar, Winald Gerritsen, Jack A Schalken
Major advances through tumor profiling technologies, that include next-generation sequencing, epigenetic, proteomic and transcriptomic methods, have been made in primary prostate cancer, providing novel biomarkers that may guide precision medicine in the near future. Areas covered: The authors provided an overview of novel molecular biomarkers in tissue, blood and urine that may be used as clinical tools to assess prognosis, improve selection criteria for active surveillance programs, and detect disease relapse early in localized prostate cancer...
June 21, 2017: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/28632102/effect-of-transient-perturbations-of-short-term-memory-on-target-directed-blind-locomotion
#2
Sarah Piekarski, Yves Lajoie, Nicole Paquet
It is difficult to walk without vision to a nearby destination if there is a time delay between watching the destination and walking toward it. Indeed, path deviation occurred when delays were introduced before initiating straight ahead blindfolded walking (R. A. Tyrrell, K. K., Rudolph, B. G., Eggers, & H. W. Leibowitz, 1993 ). The questions are whether the location of a 60-s delay in the walking path and whether performing a cognitive task during the delay influence the accuracy in reaching a previously seen target while walking without vision...
March 2, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28630719/hip-arthroscopy-results-in-improved-patient-reported-outcomes-compared-to-non-operative-management-of-waitlisted-patients
#3
Luke Spencer-Gardner, Ruch Dissanayake, Amir Kalanie, Parminder Singh, John O'Donnell
Hip arthroscopy (HA) is an established treatment option to address intra-articular pathology of the hip. However, some clinicians encourage non-operative management (NOM). Non-operative management may include active measures such as physiotherapy and intra-articular steroid injections, or NOM may involve so called watchful waiting with no active intervention. These approaches, along with surgery have been detailed recently in the Warwick Agreement, a Consensus Statement regarding diagnosis and treatment of Femoroacetabular Impingement Syndrome The aim of this study is to compare the change in clinical outcome scores of waitlisted patients with intra-articular hip pathology who receive no active treatment with matched controls that have undergone HA...
January 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/28624406/global-longitudinal-strain-in-asymptomatic-chronic-aortic%C3%A2-regurgitation-the-missing-piece-for-the-watchful-waiting-puzzle
#4
EDITORIAL
João L Cavalcante
No abstract text is available yet for this article.
June 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28609648/when-no-treatment-is-the-best-treatment-active-surveillance-strategies-for-low-risk-prostate-cancers
#5
REVIEW
V Stavrinides, C C Parker, C M Moore
Although the incidence of prostate cancer is rising due to PSA screening and increased life expectancy, the metastatic potential of low-grade, organ-confined disease remains low. An increasing number of studies suggest that radical treatment in such cases confers little or no survival benefit at a significant cost to morbidity. Active surveillance is a promising management approach of such low-risk cancers: eligible patients are selected based on clinical and pathological findings at diagnosis and are regularly monitored with digital rectal examinations, PSA testing and biopsies...
May 23, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28595267/cholesterol-uptake-and-regulation-in-high-grade-and-lethal-prostate-cancers
#6
Konrad H Stopsack, Travis A Gerke, Ove Andrén, Swen-Olof Andersson, Edward L Giovannucci, Lorelei A Mucci, Jennifer R Rider
Lethal prostate cancers have higher expression of squalene monooxygenase (SQLE), the second rate-limiting enzyme of cholesterol synthesis. Preclinical studies suggested that aberrant cholesterol regulators, receptors, and transporters contribute to cholesterol accumulation uniformly. We assessed their association with features of aggressive cancers. In the prospective prostate cancer cohorts within the Health Professional Follow-up Study, the Physicians' Health Study, and the Swedish Watchful Waiting Study, tumor mRNA expression profiling was performed...
June 8, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/28593422/treatment-of-asymptomatic-aortic-valve-stenosis-watchful-waiting-or-early-intervention
#7
J Ledwoch, H Thiele
There is ongoing debate about the optimal management of severe asymptomatic aortic stenosis (AS). Thus far, current guidelines recommend a watchful waiting strategy for the majority of asymptomatic patients. However, data on the prognosis of asymptomatic AS are inconsistent. Some reports claim an increased risk of complications and even mortality in this subset of patients when treated conservatively. Several factors are considered to contribute to the impaired outcome of asymptomatic patients, such as progressive myocardial damage or sudden cardiac death, during the watchful waiting period...
June 7, 2017: Herz
https://www.readbyqxmd.com/read/28592744/treatment-advances-and-prognosis-for-patients-with-adult-t-cell-leukemia-lymphoma
#8
Hiroo Katsuya, Kenji Ishitsuka
A classification for adult T-cell leukemia-lymphoma (ATL) based on clinical features was proposed in 1991: acute, lymphoma, chronic, and smoldering types, and their median survival times (MSTs) were reported to be 6.2, 10.2, 24.3 months, and not reached, respectively. Several new therapies for ATL have since been developed, i.e. dose-intensity multi-agent chemotherapies, allogeneic hematopoietic stem cell transplantation (allo-HSCT), monoclonal antibodies, and anti-viral therapy. The monoclonal antibody to CCR4, mogamulizumab, clearly improved response rates in patients with treatment-naïve and relapsed aggressive ATL, and has the potential to provide a survival advantage...
June 8, 2017: Journal of Clinical and Experimental Hematopathology: JCEH
https://www.readbyqxmd.com/read/28590810/worth-the-wait-leisure-can-be-just-as-enjoyable-with-work-left-undone
#9
Ed O'Brien, Ellen Roney
Four studies reveal that (a) people hold a robust intuition about the order of work and leisure and that (b) this intuition is sometimes mistaken. People prefer saving leisure for last, believing they would otherwise be distracted by looming work (Study 1). In controlled experiments, however, although subjects thought their enjoyment would be spoiled when they played a game before rather than after a laborious problem-solving task, got a massage before rather than after midterms, and consumed snacks and watched videos before rather than after a stressful performance, in reality these experiences were similarly enjoyable regardless of order (Studies 2 through 4)...
June 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28589395/testosterone-therapy-on-active-surveillance-and-following-definitive-treatment-for-prostate-cancer
#10
REVIEW
Vishnukamal Golla, Alan L Kaplan
PURPOSE OF REVIEW: Previously considered an absolute contraindication, the use of testosterone therapy in men with prostate cancer has undergone an important paradigm shift. Recent data has changed the way we approach the treatment of testosterone deficiency in men with prostate cancer. In the current review, we summarize and analyze the literature surrounding effects of testosterone therapy on patients being treated in an active surveillance protocol as well as following definitive treatment for prostate cancer...
July 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28585677/sciatic-nerve-injuries-from-gluteal-intramuscular-injection-according-to-records-of-high-health-council
#11
Hakan Hadi Kadioğlu
AIM: The purpose of the study was to analyze the cases discussed in High Health Council (HHC) and to determine the solutions for the problems on gluteal intramuscular injection (IMI) applications. MATERIAL AND METHODS: In the 9 year period, the cases of IMI related sciatic nerve injury (SNI) sending to take an opinion the Turkey HHC were reviewed. Cases were analyzed in demographic information, degree of nerve damage; side of gluteal region applied on injection, injected drugs, primary disease and appropriateness of parenteral therapy indications, and management...
May 7, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28583159/exploring-the-strategies-that-midwives-in-british-columbia-use-to-promote-normal-birth
#12
Michelle M Butler
BACKGROUND: Rates of normal birth have been declining steadily over the past 20 years, despite the evidence of the benefits to mother and baby. This is most obvious in steadily increasing caesarean section rates across countries and studies of the factors involved suggest it may be more to do with the organization of maternity care and the preferences of healthcare providers than changes in maternal or demographic conditions. The proportion of women in British Columbia (BC) receiving care from a midwife continues to grow and there is a particular focus on promoting and supporting normal pregnancy and birth in the midwifery philosophy of care...
June 5, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28582434/asymptomatic-aortic-stenosis-an-assessment-of-patients-and-of-their-general-practitioners-knowledge-after-an-indexed-specialized-assessment-in-community-practice
#13
Raphaëlle-Ashley Guerbaii, Gabriel Fustier, Pierre-Vladimir Ennezat, Anne Ringle, Camille Trouillet, Pierre Graux, André Vincentelli, Christophe Tribouilloy, Sylvestre Maréchaux
BACKGROUND: Clinical and echocardiography follow-up is recommended in patients with aortic stenosis to detect symptom onset, thus a watchful waiting approach has to be safe and effective. For both AS patients and their general practitioners, evaluation of valvular heart disease (VHD) knowledge, after the indexed specialized assessment has never been measured. AIMS: To evaluate the knowledge of clinical symptoms of aortic stenosis by both patients and their general practitioner...
2017: PloS One
https://www.readbyqxmd.com/read/28576535/adherence-to-acute-otitis-media-diagnosis-and-treatment-guidelines-among-israeli-otolaryngologists
#14
Tal Marom, Mathan Bobrow, Ephraim Eviatar, Yahav Oron, Sharon Ovnat Tamir
INTRODUCTION: The recent Israeli acute otitis media (AOM) guidelines, drafted mainly by pediatricians and family physicians in 2013, addressed diagnostic and therapeutic issues, in order to reduce over-diagnosis and treatment. These guidelines are considered as the 'standard of care' for AOM management. While the adherence rate of pediatricians to previous Israeli AOM guidelines (2004) was reported to be high (>85%), the compliance of otolaryngologists has not been studied. METHODS: An anonymous 19-item questionnaire was circulated among practicing Israeli otolaryngologists (residents [n = 93], specialists [n = 283])...
April 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28572876/adult-intussusception-a-case-series-and-review
#15
Santosh Shenoy
AIM: To identify factors differentiating pathologic adult intussusception (AI) from benign causes and the need for an operative intervention. Current evidence available from the literature is discussed. METHODS: This is a case series of eleven patients over the age of 18 and a surgical consultation for "Intussusception" at a single veteran's hospital over a five-year period (2011-2016). AI was diagnosed on computed tomography (CT) scan and or flexible endoscopy (colonoscopy)...
May 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28567376/long-term-effects-of-video-capsule-endoscopy-in-the-management-of-obscure-gastrointestinal-bleeding
#16
REVIEW
Georgios Tziatzios, Paraskevas Gkolfakis, George D Dimitriadis, Konstantinos Triantafyllou
Obscure gastrointestinal bleeding (OGIB) accounts for approximately 5% of all gastrointestinal (GI) hemorrhages. It usually arises from a small bowel lesion beyond the reach of conventional endoscopy including esophagogastroduodenoscopy and colonoscopy. Video capsule endoscopy (VCE) revolutionized the evaluation of OGIB patients since it allows reliable and noninvasive visualization of the small bowel mucosal surface. Since 2001, VCE has evolved into an efficient technology integrated in clinical practice. It is the cornerstone in the algorithm of OGIB investigation given its high diagnostic yield, which compares favorably to that of double-balloon enteroscopy (DBE)...
May 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28562283/effectiveness-of-tympanostomy-tubes-for-otitis-media-a-meta-analysis
#17
REVIEW
Dale W Steele, Gaelen P Adam, Mengyang Di, Christopher H Halladay, Ethan M Balk, Thomas A Trikalinos
CONTEXT: Tympanostomy tube placement is the most common ambulatory surgery performed on children in the United States. OBJECTIVES: The goal of this study was to synthesize evidence for the effectiveness of tympanostomy tubes in children with chronic otitis media with effusion and recurrent acute otitis media. DATA SOURCES: Searches were conducted in Medline, the Cochrane Central Trials Registry and Cochrane Database of Systematic Reviews, Embase, and the Cumulative Index to Nursing and Allied Health Literature...
May 16, 2017: Pediatrics
https://www.readbyqxmd.com/read/28560534/exercise-testing-and-stress-imaging-in-aortic-valve-disease
#18
REVIEW
Luc A Pierard, Raluca Dulgheru
Aortic valve disease and especially aortic stenosis (AS) is a growing cardiac pathology. Aortic valve replacement (AVR) is still the only treatment with proven benefit on survival in symptomatic patients and in patients with a left ventricular ejection fraction (LVEF) <50%. The benefit of prophylactic AVR in asymptomatic patients is still unproven. Once symptoms develop, the prognosis worsens. Exercise testing has emerged as a tool to unmask the "pseudo-asymptomatic" patients with AS (those without self-reporting symptoms), to link "exercise induced dyspnea" more confidently and more objectively to aortic valve disease and to allow for a safe "watchful waiting strategy" in "pseudo-symptomatic" patients (those with dyspnea unrelated to aortic valve disease)...
July 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28557798/thermal-ablation-of-a-confluent-lesion-in-the-porcine-kidney-with-a-clinically-available-mr-hifu-system
#19
J M M van Breugel, M de Greef, J W Wijlemans, G Schubert, M A A J van den Bosch, C T W Moonen, M G Ries
The incidence of small renal masses (SRMs) sized  <4 cm has increased over the decades (as co-findings/or due to introduction of cross sectional imaging). Currently, partial nephrectomy (PN) or watchful waiting is advised in these patients. Ultimately, 80-90% of these SRMs require surgical treatment and PN is associated with a 15% complication rate. In this aging population, with possible comorbidities and poor health condition, both PN and watchful waiting are non-ideal treatment options. This resulted in an increased need for early, non-invasive treatment strategies such as MR-guided high intensity focused ultrasound (MR-HIFU)...
July 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28552151/supratentorial-cavernous-malformations
#20
Jason A Ellis, Daniel L Barrow
Supratentorial cavernous malformations are uncommon cerebral vascular lesions that may present many unique challenges for treating physicians. The vast majority will be discovered during workup for seizures or after symptomatic intracerebral hemorrhage. Supratentorial cavernous malformations are increasingly being discovered incidentally in patients who obtain brain imaging for unrelated reasons. Management strategies including watchful waiting, antiepileptic drug therapy, microsurgery, or an expanding array of "minimally invasive" therapies...
2017: Handbook of Clinical Neurology
keyword
keyword
99047
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"