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JOURNAL ARTICLE
Davide Christian Orazi, Bhoomija Ranjan, Yimin Cheng
UNLABELLED: Non-face (NF) emojis are increasingly used to complement or substitute words in digital marketing messages, yet the effects, mechanisms, and contingencies of this communication strategy remain underexplored. In a large-scale longitudinal study of Airbnb listings, we show that NF emojis (vs. simple text) lead to an increase in eWOM volume, an effect we replicate experimentally. This effect is qualified by important boundary conditions whose underlying mechanisms are investigated in two additional experimental studies...
January 20, 2023: Journal of the Academy of Marketing Science
#22
MULTICENTER STUDY
Miguel D Cantu, Rashmi Kanagal-Shamanna, Sa A Wang, Tapan Kadia, Carlos E Bueso-Ramos, Sanjay S Patel, Julia T Geyer, Wayne Tam, Yazan Madanat, Peng Li, Tracy I George, Meredith M Nichols, Heesun J Rogers, Yen-Chun Liu, Nidhi Aggarwal, Jason H Kurzer, Danielle L V Maracaja, Eric D Hsi, Feras Zaiem, Daniel Babu, Kathryn Foucar, Dorottya Laczko, Adam Bagg, Attilio Orazi, Daniel A Arber, Robert P Hasserjian, Olga K Weinberg
PURPOSE: Therapy-related acute myeloid leukemias (t-AML) are a heterogenous group of aggressive neoplasms that arise following exposure to cytotoxic chemotherapy and/or ionizing radiation. Many therapy-related myeloid neoplasms (t-MN) are associated with distinct chromosomal aberrations and/or TP53 alterations, but little is known about the clinicopathologic and molecular features of normal karyotype t-AML (NK-t-AML) and whether this t-MN subtype is distinctly different from NK de novo AML (NK-dn-AML)...
January 2023: JCO Precision Oncology
#23
Maria Chiara Lucchetti, Francesca Diomedi-Camassei, Cinzia Orazi, Alice Tassi
Sclerosing stromal tumor (SST) is a rare ovarian tumor arising from the sex cord-stromal cells that occurs mainly in young adults during the second and third decades of life and rarely in pediatric and adolescent populations. The objective of this study is to report three illustrative cases of SST in young girls who had undergone surgery at our clinic in or after 2009, and to perform a literature review of this rare ovarian tumor. A retrospective chart review of female patients aged <18 years with a diagnosis of SST treated in a tertiary pediatric hospital was performed...
January 5, 2023: Pediatric Reports
#24
Jürgen Thiele, Hans Michael Kvasnicka, Attilio Orazi, Umberto Gianelli, Naseema Gangat, Alessandrom M Vannucchi, Tiziano Barbui, Daniel A Arber, Ayalew Tefferi
No abstract text is available yet for this article.
March 2023: American Journal of Hematology
#25
REVIEW
Umberto Gianelli, Jürgen Thiele, Attilio Orazi, Naseema Gangat, Alessandro M Vannucchi, Ayalew Tefferi, Hans Michael Kvasnicka
The recently published International Consensus Classification (ICC) of myeloid neoplasms summarized the results of an in-depth effort by pathologists, oncologists, and geneticists aimed to update the 2017 World Health Organization classification system for hematopoietic tumors. Along these lines, several important modifications were implemented in the classification of myeloproliferative neoplasms (MPNs). For chronic myeloid leukemia, BCR::ABL1-positive, the definition of accelerated and blast phase was simplified, and in the BCR::ABL1-negative MPNs, the classification was slightly updated to improve diagnostic specificity with a more detailed and better validated morphologic approach and the recommendation of more sensitive molecular techniques to capture in particular early stage diseases...
January 2023: Virchows Archiv: An International Journal of Pathology
#26
EDITORIAL
Moving toward more molecular classifications of myelodysplastic syndrome and acute myeloid leukemia.
Daniel A Arber, Robert P Hasserjian, Attilio Orazi
No abstract text is available yet for this article.
March 2023: American Journal of Hematology
#27
REVIEW
Vasiliki Dritsa, Noemi Orazi, Yuan Yao, Stefano Paoloni, Maria Koui, Stefano Sfarra
Over the recent period, there has been an increasing interest in the use of pulsed infrared thermography (PT) for the non-destructive evaluation of Cultural Heritage (CH). Unlike other techniques that are commonly employed in the same field, PT enables the depth-resolved detection of different kinds of subsurface features, thus providing helpful information for both scholars and restorers. Due to this reason, several research activities are currently underway to further improve the PT effectiveness. In this manuscript, the specific use of PT for the analysis of three different types of CH, namely documentary materials, panel paintings-marquetery, and mosaics, will be reviewed...
November 23, 2022: Sensors
#28
REVIEW
Sonam Prakash, Daniel A Arber, Carlos Bueso-Ramos, Robert P Hasserjian, Attilio Orazi
The myelodysplastic syndrome/myeloproliferative neoplasms (MDS/MPN) category includes a heterogeneous group of diseases characterized by the co-occurrence of clinical and pathologic features of both myelodysplastic and myeloproliferative neoplasms. The recently published International Consensus Classification of myeloid neoplasms revised the entities included in the MDS/MPN category as well as criteria for their diagnosis. In addition to the presence of one or more increased peripheral blood cell counts as evidence of myeloproliferative features, concomitant cytopenia as evidence of ineffective hematopoiesis is now an explicit requirement to diagnose the diseases included in this category...
January 2023: Virchows Archiv: An International Journal of Pathology
#29
JOURNAL ARTICLE
Kaaren K Reichard, Ayalew Tefferi, Maymona Abdelmagid, Attilio Orazi, Christina Alexandres, Joanna Haack, Patricia T Greipp
Pure erythroid leukemia (PEL), also known as acute erythroid leukemia (AEL), is recognized as a distinct morphologic entity by both the 2016 and 2022 World Health Organization (WHO) classification system. By contrast, the 2022 International Consensus Classification (ICC) includes PEL under a broader category of "acute myeloid leukemia with mutated TP53". We identified 41 Mayo Clinic cases of PEL (mean age 66 years, range 27-86; 71% males) and provide a comprehensive account of bone marrow morphology, immunophenotype, cytogenetic and mutation profiles...
November 2, 2022: Blood Cancer Journal
#30
EDITORIAL
Attilio Orazi, Robert P Hasserjian, Mario Cazzola, Hartmut Döhner, Ayalew Tefferi, Daniel A Arber
No abstract text is available yet for this article.
October 31, 2022: American Journal of Hematology
#31
REVIEW
Robert P Hasserjian, Attilio Orazi, Alberto Orfao, Maria Rozman, Sa A Wang
The International Consensus Classification (ICC) of myeloid neoplasms and acute leukemia has updated the classification of myelodysplastic syndromes (MDSs) and placed MDS in a broader group of clonal cytopenias that includes clonal cytopenia of undetermined significance (CCUS) and related entities. Although subject to some interobserver variability and lack of specificity, morphologic dysplasia remains the main feature that distinguishes MDS from other clonal cytopenias and defines MDS as a hematologic malignancy...
January 2023: Virchows Archiv: An International Journal of Pathology
#32
REVIEW
Olga K Weinberg, Anna Porwit, Attilio Orazi, Robert P Hasserjian, Kathryn Foucar, Eric J Duncavage, Daniel A Arber
Acute myeloid leukemias (AMLs) are overlapping hematological neoplasms associated with rapid onset, progressive, and frequently chemo-resistant disease. At diagnosis, classification and risk stratification are critical for treatment decisions. A group with expertise in the clinical, pathologic, and genetic aspects of these disorders developed the International Consensus Classification (ICC) of acute leukemias. One of the major changes includes elimination of AML with myelodysplasia-related changes group, while creating new categories of AML with myelodysplasia-related cytogenetic abnormalities, AML with myelodysplasia-related gene mutations, and AML with mutated TP53...
January 2023: Virchows Archiv: An International Journal of Pathology
#33
REVIEW
Roos J Leguit, Sa A Wang, Tracy I George, Alexandar Tzankov, Attilio Orazi
Mastocytosis is a neoplasm characterized by a clonal proliferation of mast cells, which accumulate in one or multiple organs, associated with an extremely heterogeneous clinical presentation. The disease can be limited to the skin (cutaneous mastocytosis) that is mostly seen in childhood and usually behaves in a benign fashion. Adult patients most often present with systemic disease with or without skin lesions. This includes indolent forms such as indolent systemic mastocytosis and its subvariant bone marrow mastocytosis, and smoldering systemic mastocytosis as well as aggressive forms including aggressive systemic mastocytosis, systemic mastocytosis with an associated myeloid neoplasm (previously called systemic mastocytosis with an associated hematologic neoplasm), and mast cell leukemia...
January 2023: Virchows Archiv: An International Journal of Pathology
#34
REVIEW
Jürgen Thiele, Hans Michael Kvasnicka, Attilio Orazi, Umberto Gianelli, Naseema Gangat, Alessandro M Vannucchi, Tiziano Barbui, Daniel A Arber, Ayalew Tefferi
A group of international experts, including hematopathologists, oncologists, and geneticists were recently summoned (September 2021, Chicago, IL, USA) to update the 2016/17 World Health Organization classification system for hematopoietic tumors. After careful deliberation, the group introduced the new International Consensus Classification (ICC) for Myeloid Neoplasms and Acute Leukemias. This current in-depth review focuses on the ICC-2022 category of JAK2 mutation-prevalent myeloproliferative neoplasms (MPNs): essential thrombocythemia, polycythemia vera, primary myelofibrosis, and MPN, unclassifiable...
January 2023: American Journal of Hematology
#35
JOURNAL ARTICLE
Eric J Duncavage, Adam Bagg, Robert P Hasserjian, Courtney D DiNardo, Lucy A Godley, Ilaria Iacobucci, Siddhartha Jaiswal, Luca Malcovati, Alessandro M Vannucchi, Keyur P Patel, Daniel A Arber, Maria E Arcila, Rafael Bejar, Nancy Berliner, Michael J Borowitz, Susan Branford, Anna L Brown, Catherine A Cargo, Hartmut Döhner, Brunangelo Falini, Guillermo Garcia-Manero, Torsten Haferlach, Eva Hellström-Lindberg, Annette S Kim, Jeffery M Klco, Rami Komrokji, Mignon Lee-Cheun Loh, Sanam Loghavi, Charles G Mullighan, Seishi Ogawa, Attilio Orazi, Elli Papaemmanuil, Andreas Reiter, David M Ross, Michael Savona, Akiko Shimamura, Radek C Skoda, Francesc Solé, Richard M Stone, Ayalew Tefferi, Matthew J Walter, David Wu, Benjamin L Ebert, Mario Cazzola
Myeloid neoplasms and acute leukemias derive from the clonal expansion of hematopoietic cells driven by somatic gene mutations. Although assessment of morphology plays a crucial role in the diagnostic evaluation of patients with these malignancies, genomic characterization has become increasingly important for accurate diagnosis, risk assessment, and therapeutic decision making. Conventional cytogenetics, a comprehensive and unbiased method for assessing chromosomal abnormalities, has been the mainstay of genomic testing over the past several decades and remains relevant today...
November 24, 2022: Blood
#36
REVIEW
Alexandar Tzankov, Kaaren K Reichard, Robert P Hasserjian, Daniel A Arber, Attilio Orazi, Sa A Wang
This review addresses changes and updates in eosinophilic disorders under the International Consensus Classification (ICC). The previous category of myeloid/lymphoid neoplasm with eosinophilia (M/LN-eo) and a specific gene rearrangement is changed to M/LN-eo with tyrosine kinase gene fusions to reflect the underlying genetic lesions. Two new members, M/LN-eo with ETV6::ABL1 fusion and M/LN-eo with various FLT3 fusions, have been added to the category; and M/LN-eo with PCM1::JAK2 and its genetic variants ETV6::JAK2 and BCR::JAK2 are recognized as a formal entity from their former provisional status...
September 7, 2022: Virchows Archiv: An International Journal of Pathology
#37
JOURNAL ARTICLE
Basilio Randazzo, Matteo Zarantoniello, Giulia Secci, Filippo Faccenda, Francesca Fava, Giulia Marzorati, Alessia Belloni, Francesca Maradonna, Veronica Orazi, Roberto Cerri, Michele Povinelli, Giuliana Parisi, Elisabetta Giorgini, Ike Olivotto
Carpione ( Salmo carpio , Linnaeus 1758) is an endangered precious endemism of Lake Garda (Northern Italy), the largest Italian lake. To date, several bottlenecks about its culture remain unsolved, including the identification of a proper growth-out diet. The aim of the present study was to test four different grossly isolipidic, isoproteic, and isoenergetic diets in which the main ingredients had a different origin. Specifically, a diet currently used by local farmers for carpione culture, largely based on marine ingredients, was used as control (CTRL), while the other three diets were formulated by partially replacing marine ingredients with plant ones (VEG) or with different percentages of processed animal proteins (PAP1 and PAP2)...
July 27, 2022: Animals: An Open Access Journal From MDPI
#38
REVIEW
R J Leguit, A Orazi, N Kucine, H M Kvasnicka, U Gianelli, D A Arber, A Porwit, M Ponzoni
The first section of the bone marrow workshop of the European Association of Haematopathology 2020 Virtual Meeting was dedicated to pediatric myeloid neoplasms. The section covered the whole spectrum of myeloid neoplasms, including myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), myelodysplastic/myeloproliferative neoplasms (MDS/MPN), and acute myeloid leukemia. The workshop cases are hereby presented, preceded by an introduction on these overall rare diseases in this age group. Very rare entities such as primary myelofibrosis, pediatric MDS with fibrosis, and MDS/MPN with JMML-like features and t(4;17)(q12;q21); FIP1L1::RARA fusion, are described in more detail...
July 11, 2022: Virchows Archiv: An International Journal of Pathology
#39
JOURNAL ARTICLE
Leandro Barbagelata, Walter Masson, Diego Iglesias, Ezequiel Lillo, Juan Francisco Migone, Maria Laura Orazi, Joaquin Maritano Furcada
Background and aim: Several reports have shown the persistence of long term symptoms after the initial COVID-19 infection (post-COVID-19 syndrome). The objective of this study was to analyze the characteristics of cardiopulmonary exercise testing (CPET) performed in patients with a history of COVID-19, comparing subjects according to the presence of post-COVID-19 syndrome. Methods: A cross-sectional study was performed. Consecutive patients >18 years with history of SARS-CoV-2 infection confirmed by polymerase chain reaction test and a CPET performed between 45 and 120 days after the viral episode were included...
July 8, 2022: Medicina clínica
#40
JOURNAL ARTICLE
Daniel A Arber, Attilio Orazi, Robert P Hasserjian, Michael J Borowitz, Katherine R Calvo, Hans-Michael Kvasnicka, Sa A Wang, Adam Bagg, Tiziano Barbui, Susan Branford, Carlos E Bueso-Ramos, Jorge E Cortes, Paola Dal Cin, Courtney D DiNardo, Hervé Dombret, Eric J Duncavage, Benjamin L Ebert, Elihu H Estey, Fabio Facchetti, Kathryn Foucar, Naseema Gangat, Umberto Gianelli, Lucy A Godley, Nicola Gökbuget, Jason Gotlib, Eva Hellström-Lindberg, Gabriela S Hobbs, Ronald Hoffman, Elias J Jabbour, Jean-Jacques Kiladjian, Richard A Larson, Michelle M Le Beau, Mignon L-C Loh, Bob Löwenberg, Elizabeth Macintyre, Luca Malcovati, Charles G Mullighan, Charlotte Niemeyer, Olatoyosi M Odenike, Seishi Ogawa, Alberto Orfao, Elli Papaemmanuil, Francesco Passamonti, Kimmo Porkka, Ching-Hon Pui, Jerald P Radich, Andreas Reiter, Maria Rozman, Martina Rudelius, Michael R Savona, Charles A Schiffer, Annette Schmitt-Graeff, Akiko Shimamura, Jorge Sierra, Wendy A Stock, Richard M Stone, Martin S Tallman, Jürgen Thiele, Hwei-Fang Tien, Alexandar Tzankov, Alessandro M Vannucchi, Paresh Vyas, Andrew H Wei, Olga K Weinberg, Agnieszka Wierzbowska, Mario Cazzola, Hartmut Döhner, Ayalew Tefferi
The classification of myeloid neoplasms and acute leukemias was last updated in 2016 within a collaboration between the World Health Organization (WHO), the Society for Hematopathology, and the European Association for Haematopathology. This collaboration was primarily based on input from a clinical advisory committees (CACs) composed of pathologists, hematologists, oncologists, geneticists, and bioinformaticians from around the world. The recent advances in our understanding of the biology of hematologic malignancies, the experience with the use of the 2016 WHO classification in clinical practice, and the results of clinical trials have indicated the need for further revising and updating the classification...
September 15, 2022: Blood
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