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Chlamydia and cervical cancer

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https://www.readbyqxmd.com/read/29380356/association-between-visual-inspection-of-the-cervix-with-acetic-acid-examination-and-high-risk-human-papillomavirus-infection-chlamydia-trachomatis-neisseria-gonorrhoeae-and-trichomonas-vaginalis-in-papua-new-guinea
#1
Andrew J Vallely, Pamela J Toliman, Claire Ryan, Glennis Rai, Johanna Wapling, Josephine Gabuzzi, Antonia Kumbia, Benny Kombuk, Zure Kombati, Lisa M Vallely, Angela Kelly-Hanku, Handan Wand, Sepehr N Tabrizi, Glen D L Mola, John M Kaldor
BACKGROUND: Papua New Guinea (PNG) has among the highest estimated burdens of cervical cancer globally but currently has no national cervical screening program. Visual inspection of the cervix with acetic acid (VIA) is a low-cost screening strategy endorsed by the World Health Organization that has been adopted in many low-resource settings but not previously evaluated in PNG. AIM: To evaluate the association between VIA examination findings and high-risk HPV (hrHPV) infection; and the impact of concomitant genital Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis on the interpretation of VIA findings...
January 30, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29356877/cervical-cancer-induction-enhancement-potential-of-chlamydia-trachomatis-a-systematic-review
#2
REVIEW
Safae Karim, Tiatou Souho, Mohamed Benlemlih, Bahia Bennani
Human papillomavirus (HPV) persistent infection is the necessary but not sufficient cause of cervical cancer. Other co-factors are required to induce cell transformation that will evolve to malignant cervical cancer. These co-factors include physical elements, other sexually transmitted infections, and immune response. Chlamydia trachomatis the most common bacterial sexually transmitted infection is often asymptomatic but causes various syndromes such as cervicitis, endometritis, pelvic inflammatory disease, and infertility...
January 22, 2018: Current Microbiology
https://www.readbyqxmd.com/read/29334204/detection-of-chlamydia-trachomatis-in-pap-smear-samples-from-south-khorasan-province-of-iran
#3
Davod Javanmard, Mahmoodreza Behravan, Malaknaz Ghannadkafi, Alireza Salehabadi, Masood Ziaee, Mohammad Hasan Namaei
Background: Chlamydia trachomatis (CT), the most common bacterial sexually transmitted infection (STI), leads to pelvic inflammatory disease, infertility and chronic pelvic pain in women as well as an increased risk of vertical transmission, conjunctivitis and pneumonitis in infants. It may also be a co-factor along with human papillomavirus (HPV) in cervical cancer progression. We aimed to determine the prevalence of CT genotypes in genital specimens of women from South Khorasan, Iran and to test the association between CT and cytology statistics...
April 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29316709/screaming-body-and-silent-healthcare-providers-a-case-study-with-a-childhood-sexual-abuse-survivor
#4
REVIEW
Sigrun Sigurdardottir, Sigridur Halldorsdottir
Stressful early life experiences cause immune dysregulation across the lifespan. Despite the fact that studies have identified childhood sexual abuse (CSA) survivors as a particularly vulnerable group, only a few attempts have been made to study their lived-experience of the physical health consequences of CSA. The aim of this study was to explore a female CSA survivor's lived-experience of the physical health consequences of CSA and how she experienced the reactions of healthcare providers. Seven interviews were conducted with this 40-year-old woman, Anne, using a phenomenological research approach...
January 8, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29313867/hpv-chlamydia-trachomatis-co-infection-metagenomic-analysis-of-cervical-microbiota-in-asymptomatic-women
#5
Marisa Di Pietro, Simone Filardo, Maria Grazia Porpora, Nadia Recine, Maria Agnese Latino, Rosa Sessa
HPV and Chlamydia trachomatis are the most common causes of sexually transmitted diseases worldwide. Most infections are asymptomatic and left untreated lead to severe reproductive tract sequelae such as cervical cancer and infertility. Interestingly, C. trachomatis may also increase the susceptibility to HPV infection as well as contribute to viral persistence. Recently, a growing body of evidence has suggested that the composition of the cervico-vaginal microbiota plays a key role in the susceptibility and outcome of genital infections caused by several pathogens, including HPV and C...
January 9, 2018: New Microbiologica
https://www.readbyqxmd.com/read/29273004/impact-of-hpv-vaccination-with-gardasil%C3%A2-in-switzerland
#6
Martine Jacot-Guillarmod, Jérôme Pasquier, Gilbert Greub, Massimo Bongiovanni, Chahin Achtari, Roland Sahli
BACKGROUND: Gardasil®, a quadrivalent vaccine targeting low-risk (6, 11) and high-risk (16, 18) human papillomaviruses (HPV), has been offered to 11-14 year-old schoolgirls in Switzerland since 2008. To evaluate its success and its potential impact on cervical cancer screening, HPV genotypes were examined in 18-year-old girls five years later (sub-study 1) and in outpatients participating to cervical cancer screening before and after vaccine implementation (sub-study 2). METHODS: For sub-study 1, 3726 females aged 18 in 2013 were invited to fill a questionnaire on personal demographics and HPV risk factors and to provide a self-collected cervicovaginal sample for HPV genotyping and Chlamydia trachomatis PCR...
December 22, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29025633/association-between-male-circumcision-and-women-s-biomedical-health-outcomes-a-systematic-review
#7
Jonathan M Grund, Tyler S Bryant, Inimfon Jackson, Kelly Curran, Naomi Bock, Carlos Toledo, Joanna Taliano, Sheng Zhou, Jorge Martin Del Campo, Ling Yang, Apollo Kivumbi, Peizi Li, Sherri Pals, Stephanie M Davis
BACKGROUND: Male circumcision reduces men's risk of acquiring HIV and some sexually transmitted infections from heterosexual exposure, and is essential for HIV prevention in sub-Saharan Africa. Studies have also investigated associations between male circumcision and risk of acquisition of HIV and sexually transmitted infections in women. We aimed to review all evidence on associations between male circumcision and women's health outcomes to benefit women's health programmes. METHODS: In this systematic review we searched for peer-reviewed and grey literature publications reporting associations between male circumcision and women's health outcomes up to April 11, 2016...
November 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28923300/influence-of-co-infection-complicated-with-human-papillomavirus-on-cervical-intraepithelial-neoplasia-development-in-patients-with-atypical-squamous-cells-of-undetermined-significance
#8
Hisami Kiseki, Yutaka Tsukahara, Natsumi Tajima, Ayako Tanaka, Aya Horimoto, Naohiko Hashimura
AIM: Human papillomaviruses (HPV) infection is a primary cause of the development of cervical precancerous lesions and cervical cancer. However, the influence of other infections on intraepithelial neoplasia (CIN) development has not been fully elucidated. We evaluated the association between co-infection and CIN development in subjects with atypical squamous cells of undetermined significance (ASCUS). METHOD: Data for ASCUS subjects who had undergone testing for high risk HPV (HR-HPV) and pathological diagnosis were analyzed...
December 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28919017/molecular-characterization-of-lower-vaginal-swabs-for-human-papilloma-virus-in-association-with-chlamydia-trachomatis-infection-in-cameroonian-women
#9
Pythagore Fogue, Geraldo Djeudong, George Bouting, Elom Aglago, Gustave Simo, Smiths Lueong
Human papilloma virus (HPV) infection is an etiological factor for cervical cancer development and Chlamydia trachomatis (Ct) is considered as a cofactor. Understanding the dynamics of HPV and Ct infection could help to explain the incidence of early onset of cervical cancer (CC) observed in Cameroon. Lower vaginal swabs and sera from sexually active women were analyzed for HPV and Ct infection in association with risk factors. Questionnaires were used to document patients' lifestyle and risk factors. A total of 206 women participated in the study average 28...
September 14, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28810976/women-s-health-knowledge-and-skills-among-transitional-year-internship-trained-military-medical-officers-serving-as-independent-health-care-providers
#10
Ryan J Heitmann, Crystal B Hammons, Alison L Batig
BACKGROUND: Women comprise 14.5% of active duty service members. Delivery of women's health services is a critical component to personal, medical, and mission readiness. Our objective was to evaluate the knowledge, skills, and practices pertaining to basic elements of women's/reproductive health issues among transitional internship-trained general medical officers in the Army, Navy, and Air Force. MATERIALS AND METHODS: This is a cross-sectional survey study of transitional internship-trained graduates from 2012 to 2015 who transitioned to an operational assignment as an independent provider after internship graduation...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28694268/the-effect-of-changes-in-cervical-cancer-screening-guidelines-on-chlamydia-testing
#11
Michelle S Naimer, Jeffrey C Kwong, Deepit Bhatia, Rahim Moineddin, Michael Whelan, Michael A Campitelli, Liane Macdonald, Aisha Lofters, Ashleigh Tuite, Tali Bogler, Joanne A Permaul, Warren J McIsaac
PURPOSE: Many chlamydia infections are identified through screening, which is frequently offered to females concomitantly with cervical cancer screening. Recent cervical cancer screening guidelines recommend screening less frequently and starting later. We sought to evaluate the impact of the May 2012 Ontario, Canada, cervical cancer screening guideline change on Papanicolaou (Pap) and chlamydia trachomatis (chlamydia) testing and incidence. METHODS: We extracted population-based physician billing claims data to identify Pap and chlamydia tests and public health surveillance data to identify chlamydia cases...
July 2017: Annals of Family Medicine
https://www.readbyqxmd.com/read/28520854/declines-in-human-papillomavirus-hpv-associated-high-grade-cervical-lesions-after-introduction-of-hpv-vaccines-in-connecticut-united-states-2008-2015
#12
Linda M Niccolai, James I Meek, Monica Brackney, James L Hadler, Lynn E Sosa, Daniel M Weinberger
Background: Trends in human papillomavirus (HPV)-associated cervical lesions can provide an indication of vaccine impact. Our purpose was to measure trends in cervical lesions during 2008-2015 and to consider possible explanations including vaccination coverage, changes in screening for cervical cancer, and risk behaviors for acquiring HPV. Methods: Connecticut (CT) implemented mandatory reporting of cervical intraepithelial neoplasia grades 2/3 and adenocarcinoma in situ (cervical intraepithelial neoplasia grade 2 or higher [CIN2+]) in 2008...
September 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28453175/prevalence-of-human-papillomavirus-chlamydia-trachomatis-and-trichomonas-vaginalis-infections-in-amazonian-women-with-normal-and-abnormal-cytology
#13
E Costa-Lira, A H V L Jacinto, L M Silva, P F R Napoleão, R A A Barbosa-Filho, G J S Cruz, S Astolfi-Filho, C M Borborema-Santos
Sexually transmitted infections are an important cause of morbidity among sexually active women worldwide, and have been implicated as cofactors in the pathogenesis of cervical cancer. We investigated the prevalence of human papillomavirus (HPV), Chlamydia trachomatis (CT), and Trichomonas vaginalis (TV), and accessed the diversity of HPV in women with normal and abnormal cytology in Manaus, Brazil. We used polymerase chain reaction and HPV genotyping by direct sequencing. The chi-square test was used to calculate the absolute and relative frequencies of the categorical variables, and Fisher's test was used when P < 0...
April 28, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28368862/prevalence-of-trichomonas-vaginalis-in-women-of-reproductive-age-at-a-family-health-clinic
#14
Mateus De Paula von Glehn, Lana Cristina Evangelista Ferreira Sá, Hian Delfino Ferreira da Silva, Eleuza Rodrigues Machado
INTRODUCTION: Trichomonas vaginalis is considered the most prevalent curable sexually transmitted infection, and its occurrence exceeds that of gonococcal and chlamydia infections. This parasite has been identified as responsible for the increased risk of transmission of HIV and has also been associated with prostate and cervical cancer. Many carriers of T. vaginalis are asymptomatic and, when experiencing a health problem, they most often have nonspecific symptoms. The aim of this research was to estimate the presence of T...
March 31, 2017: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/28267862/screening-for-gynecologic-conditions-with-pelvic-examination-us-preventive-services-task-force-recommendation-statement
#15
Kirsten Bibbins-Domingo, David C Grossman, Susan J Curry, Michael J Barry, Karina W Davidson, Chyke A Doubeni, John W Epling, Francisco A R García, Alex R Kemper, Alex H Krist, Ann E Kurth, C Seth Landefeld, Carol M Mangione, William R Phillips, Maureen G Phipps, Michael Silverstein, Melissa Simon, Albert L Siu, Chien-Wen Tseng
Importance: Many conditions that can affect women's health are often evaluated through pelvic examination. Although the pelvic examination is a common part of the physical examination, it is unclear whether performing screening pelvic examinations in asymptomatic women has a significant effect on disease morbidity and mortality. Objective: To issue a new US Preventive Services Task Force (USPSTF) recommendation on screening for gynecologic conditions with pelvic examination for conditions other than cervical cancer, gonorrhea, and chlamydia, for which the USPSTF has already made specific recommendations...
March 7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28267861/periodic-screening-pelvic-examination-evidence-report-and-systematic-review-for-the-us-preventive-services-task-force
#16
REVIEW
Janelle M Guirguis-Blake, Jillian T Henderson, Leslie A Perdue
Importance: Recent changes in the periodicity of cervical cancer screening have led to questions about the role of screening pelvic examinations among asymptomatic women. Objective: To systematically review literature on health benefits, accuracy, and harms of the screening pelvic examination for gynecologic conditions for the US Preventive Services Task Force (USPSTF). Data Sources: MEDLINE, PubMed, and Cochrane Central Register of Controlled Trials for relevant English-language studies published through January 13, 2016, with surveillance through August 3, 2016...
March 7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28011911/effectiveness-of-human-papillomavirus-vaccination-on-prevalence-of-vaccine-genotypes-in-young-sexually-active-women-in-france
#17
Isabelle Heard, Laura Tondeur, Laurence Arowas, Marie Demazoin, Michaël Falguières, Isabelle Parent Du Chatelet
Background.: Effectiveness of human papillomavirus (HPV) vaccines in the context of both guidelines, which recommend vaccination at 14 years and modest vaccine coverage, is poorly documented. Methods.: Residual specimens from females aged <25 years undergoing chlamydia testing were collected, together with demographic, sexual behavior, and vaccine status data. Human pappilomavirus genotypes were determined using the PapilloCheck test system. We compared vaccine type (VT; types 6, 11, 16, 18) prevalence according to vaccination status and identified factors associated with VT prevalence...
March 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27992790/association-between-high-risk-human-papillomavirus-infection-and-co-infection-with-candida-spp-and-trichomonas-vaginalis-in-women-with-cervical-premalignant-and-malignant-lesions
#18
Ishita Ghosh, Richard Muwonge, Srabani Mittal, Dipanwita Banerjee, Pratip Kundu, Ranajit Mandal, Jaydip Biswas, Partha Basu
BACKGROUND: Human papillomavirus (HPV) is the necessary cause of cervical cancer. Cervico-vaginal infection with pathogens like Chlamydia is a likely cofactor. The interactions between HPV, Trichomonas vaginalis (TV) and Candida spp. are less understood, though inflammation induced by these pathogens has been demonstrated to facilitate oncogenesis. OBJECTIVE: Our study aimed to evaluate the association between Candida spp. and TV co-infection with HPV in cervical oncogenesis...
December 12, 2016: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/27771695/the-biological-impact-of-genomic-diversity-in-cervical-cancer-development
#19
REVIEW
Cristina Mendes de Oliveira, José Eduardo Levi
Human papillomaviruses (HPVs) are the etiologic agents of cervical cancer, the unique human neoplasia that has one single necessary cause. The diversity of HPVs is well described, with 200 HPV types existing as distinct taxonomic units and each receiving an Arabic number. On a clinical basis, they are usually grouped by their site of occurrence and disease associations. Those types inhabiting the anogenital mucosa are more intensively studied and further divided into cancer-associated HPVs, which are termed 'high risk', while those linked to benign proliferative lesions are assigned as 'low risk'...
2016: Acta Cytologica
https://www.readbyqxmd.com/read/27598277/-human-papilloma-virus-and-chlamydia-trachomatis-by-number-of-sexual-partners-and-time-of-sexual-activity-on-university-students-in-the-region-of-la-araucan%C3%A3-a-chile
#20
Angélica Melo, Nicole Lagos, Sonia Montenegro, Juan José Orellana, Ana María Vásquez, Sergio Moreno, Sandra Liempi, Pablo Guzmán, Flery Fonseca-Salamanca
BACKGROUND: Human papilloma virus (HPV) and Chlamydia trachomatis are the most prevalent sexually transmitted infections (STIs), among teenagers and young people, with risk factors: active sex life and multiple partners. Chlamydia trachomatis infection may favor HPV infection and this, the development of cervical cancer. Both infections can lead to consequences on sexual and reproductive health. OBJECTIVE: To determine frequency of HPV and C. trachomatis in asymptomatic university women less than 25 years, associating them with number of sexual partners (n°SxP) and time of sexual activity (TSxA)...
June 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
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