keyword
MENU ▼
Read by QxMD icon Read
search

New technique

keyword
https://www.readbyqxmd.com/read/27933740/fine-needle-aspiration-in-the-diagnosis-and-classification-of-hepatoblastoma-analysis-of-21-new-cases
#1
Tatjana Vlajnic, Hervé J Brisse, Isabelle Aerts, Paul Fréneaux, Cécile Cellier, Monique Fabre, Jerzy Klijanienko
BACKGROUND: Diagnosis of hepatoblastoma (HBL) is based on characteristic clinical and radiological presentation, young age and marked elevation of serum α-fetoprotein (aFP). Fine needle aspiration (FNA) technique is successfully used in the diagnosis of hepatoblastoma. To evaluate the value of FNA in the diagnosis and subtyping of HBL, we report our experience correlated to histological sections (core needle biopsy, CNB). METHODS: From 1991 to 2015, 21 cases from 20 patients were cytologically diagnosed as HBL...
December 9, 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27933602/fish-tales-the-use-of-zebrafish-xenograft-human-cancer-cell-models
#2
REVIEW
Yvette Drabsch, B Ewa Snaar-Jagalska, Peter Ten Dijke
Advances in scientific techniques have provided researchers with exceptional new opportunities to identify and monitor changes between different cancer types, during different stages of progression, between individual tumor cells and in the surrounding stroma. The wealth of information that can be obtained from new scientific techniques places additional requirements on the conventional cancer models. New models that could be used to rapidly access the (potential) functional importance of newly identified (epi)genetic and proteomic changes and test the efficacy on emerging (combinatorial) therapies are desperately required...
December 9, 2016: Histology and Histopathology
https://www.readbyqxmd.com/read/27933537/complex-genetics-of-cardiovascular-traits-in-mice-f2-mapping-of-qtls-and-their-underlying-genes
#3
Svitlana Podliesna, Connie R Bezzina, Elisabeth M Lodder
In this chapter, we will use the example of the identification of Tnni3k as a modulator of cardiac conduction to introduce you to the use of a murine F2-generation intercross as a powerful method for the identification of novel genes relevant for cardiovascular traits. Murine F2-progeny is a genetically diverse panel of mice with differences in phenotype manifestations, e.g. cardiovascular traits such as cardiomyopathy and ECG parameters. This chapter discusses the best strategies for using F2-mice for genetic mapping...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27933475/how-safe-is-minimally-invasive-pedicle-screw-placement-for-treatment-of-thoracolumbar-spine-fractures
#4
Timo Michael Heintel, Stefan Dannigkeit, Annabel Fenwick, Martin Cornelius Jordan, Hendrik Jansen, Fabian Gilbert, Rainer Meffert
STUDY DESIGN: Prospective analysis of patients who underwent minimally invasive posterior instrumentation. OBJECTIVE: The purpose of this study was to evaluate the safety of minimally invasive pedicle screw placement in patients with unstable thoracic and lumbar spine fractures using the conventional fluoroscopy technique. Although wound infection, haematoma, and new neurological deficit due to screw malplacement remain a common source of morbidity, estimates of their rates of occurrence remain relatively limited...
December 8, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27933467/osteosarcoma-overview
#5
REVIEW
Brock A Lindsey, Justin E Markel, Eugenie S Kleinerman
Osteosarcoma (OS) is the most common primary malignancy of bone and patients with metastatic disease or recurrences continue to have very poor outcomes. Unfortunately, little prognostic improvement has been generated from the last 20 years of research and a new perspective is warranted. OS is extremely heterogeneous in both its origins and manifestations. Although multiple associations have been made between the development of osteosarcoma and race, gender, age, various genomic alterations, and exposure situations among others, the etiology remains unclear and controversial...
December 8, 2016: Rheumatology and Therapy
https://www.readbyqxmd.com/read/27933351/-modern-modifications-of-uvulopalatopharyngoplasty
#6
T Verse, B A Stuck
Uvulopalatopharyngoplasty (UPPP) was first described in 1964 with regard to surgical treatment of snoring and in 1981 with regard to treatment of obstructive sleep apnea (OSA). The initial surgical techniques for OSA were very invasive, frequently leading to significant morbidity and complications. Wolfgang Pirsig et al. were the first in Germany to recognize that a radical surgical technique increased only the complications, not the efficacy of UPPP. The less invasive surgical technique developed based on these findings is still established in Germany...
December 8, 2016: HNO
https://www.readbyqxmd.com/read/27933305/robust-generation-of-transgenic-mice-by-simple-hypotonic-solution-mediated-delivery-of-transgene-in-testicular-germ-cells
#7
Abul Usmani, Nirmalya Ganguli, Subodh K Jain, Nilanjana Ganguli, Rajesh Kumar Sarkar, Mayank Choubey, Mansi Shukla, Hironmoy Sarkar, Subeer S Majumdar
Our ability to decipher gene sequences has increased enormously with the advent of modern sequencing tools, but the ability to divulge functions of new genes have not increased correspondingly. This has caused a remarkable delay in functional interpretation of several newly found genes in tissue and age specific manner, limiting the pace of biological research. This is mainly due to lack of advancements in methodological tools for transgenesis. Predominantly practiced method of transgenesis by pronuclear DNA-microinjection is time consuming, tedious, and requires highly skilled persons for embryo-manipulation...
2016: Molecular Therapy. Methods & Clinical Development
https://www.readbyqxmd.com/read/27933245/an-adaptive-switching-filter-based-on-approximated-variance-for-detection-of-impulse-noise-from-color-images
#8
K Pritamdas, Kh Manglem Singh, L Lolitkumar Singh
A new adaptive switching algorithm is presented where two adaptive filters are switched correspondingly for lower and higher noise ratio of the image. An adaptive center weighted vector median filter is used for the lower noise ratio whereas for higher noise ratio the noisy pixels are detected based on the comparison of the difference between the mean of the vector pixels in the window and the approximated variance of the vector pixels in the window. Then the window comprising the detected noisy pixel is further considered where the pixels are given exponential weights according to their similarity to the other neighboring pixels, spatially and radio metrically...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27933153/improving-pneumococcal-vaccination-rates-of-medical-inpatients-in-urban-nepal-using-quality-improvement-measures
#9
Allison Bock, Kathan Chintamaneni, Lisa Rein, Tifany Frazer, Gyan Kayastha, Theodore MacKinney
Streptococcus pneumoniae infection is associated with high morbidity and mortality in low income countries. In Nepal, there is a high lung disease burden and incidence of pneumonia due to multiple factors including indoor air pollution, dust exposure, recurrent infections, and cigarette smoking. Despite the ready availability of effective pneumococcal vaccines (PNV), vaccine coverage rates remain suboptimal globally. Quality Improvement (QI) principles could be applied to improve compliance, but it is a virtually new technology in Nepal...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27933112/osteoblast-and-stem-cell-response-to-nanoscale-topographies-a-review
#10
Nur Izzati Aminuddin, Roslina Ahmad, Sheikh Ali Akbar, Belinda Pingguan-Murphy
To understand how cells respond to the nanoscale extracellular environment in vivo, cells from various sources have been cultured on nanoscale patterns fabricated using bottom-up and top-down techniques. Human fetal osteoblasts (hFOBs) and stem cells are some of them and they are known to be overtly responsive to nanoscale topographies - allowing us to investigate the hows and whys of the response in vitro. Information gathered from these in vitro studies could be used to control the cells, i.e. make the stem cells differentiate or retain their characteristics without the use of medium supplements...
2016: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/27933101/study-of-holtermanniella-wattica-leucosporidium-creatinivorum-naganishia-adeliensis-solicoccozyma-aeria-and-solicoccozyma-terricola-for-their-lipogenic-aptitude-from-different-carbon-sources
#11
Sara Filippucci, Giorgia Tasselli, Alessandro Scardua, Simone Di Mauro, Maria Rita Cramarossa, Davide Perini, Benedetta Turchetti, Andrea Onofri, Luca Forti, Pietro Buzzini
BACKGROUND: The ability of some microorganisms to accumulate lipids is well known; however, only recently the number of studies on microbial lipid biosynthesis for obtaining oleochemical products, namely biofuels and some building blocks for chemistry, is rapidly and spectacularly increased. Since 1990s, some oleaginous yeasts were studied for their ability to accumulate lipids up to 60-70% of their dry weight. Due to the vast array of engineering techniques currently available, the recombinant DNA technology was the main approach followed so far for obtaining lipid-overproducing yeasts, mainly belonging to the Yarrowia lipolytica...
2016: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/27933028/autism-in-action-reduced-bodily-connectedness-during-social-interactions
#12
C Lieke E Peper, Sija J van der Wal, Sander Begeer
Autism is a lifelong disorder, defined by deficits in social interactions and flexibility. To date, diagnostic markers for autism primarily include limitations in social behavior and cognition. However, such tests have often shown to be inadequate for individuals with autism who are either more cognitively able or intellectually disabled. The assessment of the social limitations of autism would benefit from new tests that capture the dynamics of social initiative and reciprocity in interaction processes, and that are not dependent on intellectual or verbal skills...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27932868/analysis-of-parallel-algorithms-on-smp-node-and-cluster-of-workstations-using-parallel-programming-models-with-new-tile-based-method-for-large-biological-datasets
#13
D D Shrimankar, S R Sathe
Sequence alignment is an important tool for describing the relationships between DNA sequences. Many sequence alignment algorithms exist, differing in efficiency, in their models of the sequences, and in the relationship between sequences. The focus of this study is to obtain an optimal alignment between two sequences of biological data, particularly DNA sequences. The algorithm is discussed with particular emphasis on time, speedup, and efficiency optimizations. Parallel programming presents a number of critical challenges to application developers...
2016: Bioinformatics and Biology Insights
https://www.readbyqxmd.com/read/27932856/three-dimensional-soft-tissue-analysis-of-the-hand-a-novel-method-to-investigate-effects-of-acromegaly
#14
Inge A Hoevenaren, M A E M Wagenmakers, S H P P Roerink, R T Netea-Maier, D J O Ulrich, Thomas J J Maal
BACKGROUND: Acral overgrowth is a highly common clinical sign in patients with active acromegaly. To what extent this overgrowth persists after long-term remission of acromegaly is largely unknown. Using the new imaging technique of three-dimensional (3D) stereophotogrammetry, it is possible to accurately investigate soft tissue changes of the hand. The aim of the recent study was to compare the 3D soft tissue characteristics of the hands of patients in long-term remission of acromegaly to those of a healthy pair matched control group...
2016: European Journal of Plastic Surgery
https://www.readbyqxmd.com/read/27932531/development-of-type-2-diabetes-mellitus-phenotyping-framework-using-expert-knowledge-and-machine-learning-approach
#15
Rina Kagawa, Yoshimasa Kawazoe, Yusuke Ida, Emiko Shinohara, Katsuya Tanaka, Takeshi Imai, Kazuhiko Ohe
BACKGROUND: Phenotyping is an automated technique that can be used to distinguish patients based on electronic health records. To improve the quality of medical care and advance type 2 diabetes mellitus (T2DM) research, the demand for T2DM phenotyping has been increasing. Some existing phenotyping algorithms are not sufficiently accurate for screening or identifying clinical research subjects. OBJECTIVE: We propose a practical phenotyping framework using both expert knowledge and a machine learning approach to develop 2 phenotyping algorithms: one is for screening; the other is for identifying research subjects...
December 7, 2016: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/27932458/the-impact-of-recent-improvements-in-cryo-electron-microscopy-technology-on-the-understanding-of-bacterial-ribosome-assembly
#16
Aida Razi, Robert A Britton, Joaquin Ortega
Cryo-electron microscopy (cryo-EM) had played a central role in the study of ribosome structure and the process of translation in bacteria since the development of this technique in the mid 1980s. Until recently cryo-EM structures were limited to ∼10 Å in the best cases. However, the recent advent of direct electron detectors has greatly improved the resolution of cryo-EM structures to the point where atomic resolution is now achievable. This improved resolution will allow cryo-EM to make groundbreaking contributions in essential aspects of ribosome biology, including the assembly process...
December 8, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27932302/hippocampal-asymmetry-differences-in-the-left-and-right-hippocampus-proteome-in-the-rat-model-of-temporal-lobe-epilepsy
#17
Leila Sadeghi, Albert Anatolyevich Rizvanov, Ilnur Ildusovich Salafutdinov, Bahareh Dabirmanesh, Mohammad Sayyah, Yaghoub Fathollahi, Khosro Khajeh
: The hippocampus is a complex brain structure and undergoes severe sclerosis and gliosis in temporal lobe epilepsy (TLE) as the most common type of epilepsy. The key features of the TLE may be reported in chronic animal models of epilepsy, such as pilocarpine model. Therefore, the current study was conducted in a rat pilocarpine model of acquired epilepsy. Two-dimensional gel electrophoresis based proteomic technique was used to compare the proteome map of the left and right hippocampus in both control and epileptic rats...
December 5, 2016: Journal of Proteomics
https://www.readbyqxmd.com/read/27932150/real-time-intraoperative-fluorescent-lymphography-a-new-technique-for-lymphatic-sparing-surgery
#18
G Ietto, F Amico, G Soldini, C Chiappa, M Franchin, D Iovino, A Romanzi, G Saredi, E Cassinotti, L Boni, M Tozzi, G Carcano
BACKGROUND: Many surgical procedures can produce persistent lymphorrhea, lymphoceles, and lymphedema after lymph node and lymph vessel damage. Appropriate visualization of the lymphatic system is challenging. Indocyanine green (ICG) is a well-known nontoxic dye for lymphatic flow evaluation. ICG fluorescence-guided lymphography has emerged as a promising technique for intraoperative lymphatic mapping. OBJECTIVE: Our goal was to develop a high spatial resolution, real-time intraoperative imaging technique to avoid or recognize early deep lymphatic vessel damage...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27932033/cellular-analysis-of-trophoblast-and-placenta
#19
Frances Wong, Brian J Cox
The placenta is composed of two lineages: the trophoblast and mesoderm. While morphological assessment of the placenta has highlighted major cell types and developmental structures, the human placenta is relatively unexplained on a molecular level. Current molecular analysis of the placenta has largely been confined to assessing whole organs that include both cell lineages and their differentiated progeny. This has confounded our understanding of the processes of placental development and function for two reasons...
November 30, 2016: Placenta
https://www.readbyqxmd.com/read/27931969/human-papillomaviruses-in-colorectal-cancers-a-case-control-study-in-western-patients
#20
Lucine Vuitton, Carine Jaillet, Elise Jacquin, Franck Monnien, Marine Heberle, Maria I Mihai, Catherine Lassabe, Johnny Raffoul, Marc Puyraveau, Zaher Lakkis, Najib Lamfichekh, Alain Picard, Jean-Luc Prétet, Christiane Mougin, Séverine Valmary-Degano
BACKGROUND: Colorectal cancer (CRC) is one of the most common cancers. As in other cancer locations, the involvement of human papillomaviruses (HPV) has been suggested but remains highly debated with wide differences among reported prevalence of HPV infection in CRCs. AIM: To determine the actual prevalence of high risk HPV16 and 18 in a large case-control study. METHODS: CRC specimens were used for analysis of both tumor and distant healthy tissue...
November 14, 2016: Digestive and Liver Disease
keyword
keyword
98966
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"