K Konarska-Bajda, P Ceranowicz, J Cieszkowski, G Ginter, A Chmura, A Stempniewicz, K Galazka, B Kusmierz-Cabala, P Dumnicka, J Bonior, M Sporek, T Brzozowski, Z Warzecha
Acute pancreatitis (AP) is the most common gastrointestinal disease leading to hospitalizations and unexpected deaths. The development of AP leads to damage of the pancreatic microcirculation with a cascade of subsequent events resulting, among others, in coagulopathy. Previous research showed that anticoagulants can be important therapeutic agents. Heparin and acenocoumarol can alleviate the course of AP, as well as accelerate healing and post-inflammatory regeneration of the pancreas. The aim of this study was to determine whether warfarin, a drug with more stable effects than acenocoumarol, affects the healing and regeneration of the pancreas in the cerulein-induced AP...
August 2023: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society