Read by QxMD icon Read


S Dalbouha, M L Senent, N Komiha, R Domínguez-Gómez
Various astrophysical relevant molecules obeying the empirical formula C2H3NO are characterized using explicitly correlated coupled cluster methods (CCSD(T)-F12). Rotational and rovibrational parameters are provided for four isomers: methyl isocyanate (CH3NCO), methyl cyanate (CH3OCN), methyl fulminate (CH3ONC), and acetonitrile N-oxide (CH3CNO). A CH3CON transition state is inspected. A variational procedure is employed to explore the far infrared region because some species present non-rigidity. Second order perturbation theory is used for the determination of anharmonic frequencies, rovibrational constants, and to predict Fermi resonances...
September 28, 2016: Journal of Chemical Physics
Athanasios Athanasiadis, Clare Fitzgerald, Nicholas M Davidson, Chiara Giorio, Stanley W Botchway, Andrew D Ward, Markus Kalberer, Francis D Pope, Marina K Kuimova
Organic aerosols (OAs) play important roles in multiple atmospheric processes, including climate change, and can impact human health. The physico-chemical properties of OAs are important for all these processes and can evolve through reactions with various atmospheric components, including oxidants. The dynamic nature of these reactions makes it challenging to obtain a true representation of their composition and surface chemistry. Here we investigate the microscopic viscosity of the model OA composed of squalene, undergoing chemical aging...
October 26, 2016: Physical Chemistry Chemical Physics: PCCP
Mohammad T Mazhab-Jafari, Alexis Rohou, Carla Schmidt, Stephanie A Bueler, Samir Benlekbir, Carol V Robinson, John L Rubinstein
Vacuolar-type ATPases (V-ATPases) are ATP-powered proton pumps involved in processes such as endocytosis, lysosomal degradation, secondary transport, TOR signalling, and osteoclast and kidney function. ATP hydrolysis in the soluble catalytic V1 region drives proton translocation through the membrane-embedded VO region via rotation of a rotor subcomplex. Variability in the structure of the intact enzyme has prevented construction of an atomic model for the membrane-embedded motor of any rotary ATPase. We induced dissociation and auto-inhibition of the V1 and VO regions of the V-ATPase by starving the yeast Saccharomyces cerevisiae, allowing us to obtain a ~3...
October 24, 2016: Nature
Boqian Sun, Shunyue Wang, Haixia Li, Xiaoxia He
A micromachined gyroscope in which a high-speed spinning rotor is suspended electrostatically in a vacuum cavity usually functions as a dual-axis angular rate sensor. An inherent coupling error between the two sensing axes exists owing to the angular motion of the spinning rotor being controlled by a torque-rebalance loop. In this paper, a decoupling compensation method is proposed and investigated experimentally based on an electrostatically suspended micromachined gyroscope. In order to eliminate the negative spring effect inherent in the gyroscope dynamics, a stiffness compensation scheme was utilized in design of the decoupled rebalance loop to ensure loop stability and increase suspension stiffness...
October 20, 2016: Sensors
Michael R Dent, Ismael López-Duarte, Callum J Dickson, Phoom Chairatana, Harry L Anderson, Ian R Gould, Douglas Wylie, Aurimas Vyšniauskas, Nicholas J Brooks, Marina K Kuimova
Molecular rotors have emerged as versatile probes of microscopic viscosity in lipid bilayers, although it has proved difficult to find probes that stain both phases equally in phase-separated bilayers. Here, we investigate the use of a membrane-targeting viscosity-sensitive fluorophore based on a thiophene moiety with equal affinity for ordered and disordered lipid domains to probe ordering and viscosity within artificial lipid bilayers and live cell plasma membranes.
October 24, 2016: Chemical Communications: Chem Comm
Rui-Qin Zhang, Yan-Ling Zhao, Fei Qi, Klaus Hermann, Michel A Van Hove
Rotation-inducing torque is ubiquitous in many molecular systems. We present a straightforward theoretical method based on forces acting on atoms and obtained from atomistic quantum mechanics calculations to quickly and qualitatively determine whether a molecule or sub-unit thereof has a tendency to rotate and, if so, around which axis and in which sense: clockwise or counterclockwise. The method also indicates which atoms, if any, are predominant in causing the rotation. Our computational approach can in general efficiently provide insights into the internal rotational degrees of freedom of all molecules and help to theoretically screen or modify them in advance of experiments or to efficiently guide a detailed analysis of their rotational behavior with more extensive computations...
October 24, 2016: Physical Chemistry Chemical Physics: PCCP
Nir Uriel, Sirtaz Adatya, Jiří Malý, Eric Kruse, Daniel Rodgers, Gerald Heatley, Aleš Herman, Poornima Sood, Dominik Berliner, Johann Bauersachs, Axel Haverich, Michael Želízko, Jan D Schmitto, Ivan Netuka
BACKGROUND: The HeartMate 3 (HM3) is a Conformiteé Européenne (CE) mark-approved left ventricular assist device (LVAD) with a fully magnetically levitated rotor with features consisting of a wide range of operational speeds, wide flow paths and an artificial pulse. We performed a hemodynamic and echocardiographic evaluation of patients implanted with the HM3 LVAD to assess the speed range for optimal hemodynamic support. METHODS: Sixteen HM3 patients underwent pump speed ramp tests with right heart catheterization (including central venous pressure [CVP], pulmonary artery pressure, pulmonary capillary wedge pressure [PCWP] and blood pressure [BP]) and 3-dimensional echocardiography (3DE)...
July 17, 2016: Journal of Heart and Lung Transplantation
Masahiro Ito, Yuka Takahashi
Prior to 2008, all previously studied conventional bacterial flagellar motors appeared to utilize either H(+) or Na(+) as coupling ions. Membrane-embedded stator complexes support conversion of energy using transmembrane electrochemical ion gradients. The main H(+)-coupled stators, known as MotAB, differ from Na(+)-coupled stators, PomAB of marine bacteria, and MotPS of alkaliphilic Bacillus. However, in 2008, a MotAB-type flagellar motor of alkaliphilic Bacillus clausii KSM-K16 was revealed as an exception with the first dual-function motor...
October 22, 2016: Extremophiles: Life Under Extreme Conditions
Gabriel Lima-Oliveira, Dorothy M Adcock, Gian Luca Salvagno, Emmanuel J Favaloro, Giuseppe Lippi
OBJECTIVE: Thus study was aimed to investigate whether the mixing technique could influence the results of routine and specialized clotting tests on post-thawed specimens. METHODS: The sample population consisted of 13 healthy volunteers. Venous blood was collected by evacuated system into three 3.5mL tubes containing 0.109mmol/L buffered sodium citrate. The three blood tubes of each subject were pooled immediately after collection inside a Falcon 15mL tube, then mixed by 6 gentle end-over-end inversions, and centrifuged at 1500g for 15min...
October 18, 2016: Clinical Biochemistry
Stefan Georg Spitzer, László Károlyi, Carola Rämmler, Frank Scharfe, Thomas Weinmann, Mirko Zieschank, Anke Langbein
INTRODUCTION: A patient-tailored ablation approach focused on the elimination of both pulmonary vein triggers as well as substrate drivers may result in favourable outcomes with recurrent persistent AF patients. OBJECTIVE: We evaluated the long-term outcomes of rotor ablation combined with conventional pulmonary vein isolation (PVI) in patients with recurrent non-paroxysmal AF. METHODS: 58 consecutive patients underwent FIRM-guided rotor ablation followed by conventional PVI for the treatment of recurrent non-paroxysmal AF...
October 21, 2016: Journal of Cardiovascular Electrophysiology
Rebecca S Nader, Anthony L Murkar, Carlyle T Smith
Recent research has suggested that some of the inter-individual variation in sleep spindle activity is due to innate learning ability. Sleep spindles have also been observed to vary following learning in both young and older adults. We examined the effect of procedural task acquisition on sleep stages and on sleep spindles in an adolescent sample. Participants were 32 adolescents (17 females) between the ages of 12 and 19 years. Spindle activity was examined in three different frequency ranges: 11.00-13.50 Hz (slow), 13...
2016: Frontiers in Psychology
Dhananjai Saranadhi, Dayong Chen, Justin A Kleingartner, Siddarth Srinivasan, Robert E Cohen, Gareth H McKinley
Skin friction drag contributes a major portion of the total drag for small and large water vehicles at high Reynolds number (Re). One emerging approach to reducing drag is to use superhydrophobic surfaces to promote slip boundary conditions. However, the air layer or "plastron" trapped on submerged superhydrophobic surfaces often diminishes quickly under hydrostatic pressure and/or turbulent pressure fluctuations. We use active heating on a superhydrophobic surface to establish a stable vapor layer or "Leidenfrost" state at a relatively low superheat temperature...
October 2016: Science Advances
Jingbo Wei, Kun Liu, Gianmarco Radice
This paper presents a novel and simple method to analyze the absolute stability and the rotor speed stable region of a magnetically suspended rotor (MSR). At the beginning of the paper, a complex variable is introduced to describe the movement of the MSR and a complex coefficient transfer function is obtained accordingly. The equivalent stability relationship between this new variable and the two traditional deflection angles is also demonstrated in a simple way. The detailed characteristics of the open-loop MSR system with time delay are studied carefully based on the characteristics of its Nyquist curve...
October 13, 2016: ISA Transactions
G André Ng
Antiarrhythmic drug therapy has seen significant challenges over the past 3 decades with unexpected results from clinical trials such as CAST, SWORD and more recently PALLAS showing harm in patients whom antiarrhythmic drugs were given based on their intended antiarrhythmic actions and previously demonstrated efficacy. These results question whether the precise mechanism of action of the drugs was understood and highlight the complexity of the situation where there is the combination of multiple actions of the antiarrhythmic drugs on various molecular systems, some of which may be unknown with associated adverse outcome, and their interaction with pre-existing abnormality in disease states in patients treated...
October 12, 2016: Pharmacology & Therapeutics
M Bitter, V Milner
The periodically kicked rotor is a paradigm system for studying quantum effects on classically chaotic dynamics. The wave function of the quantum rotor localizes in angular momentum space, similarly to Anderson localization of the electronic wave function in disordered solids. Here, we observe dynamical localization in a system of true quantum rotors by subjecting nitrogen molecules to periodic sequences of femtosecond pulses. Exponential distribution of the molecular angular momentum-the hallmark of dynamical localization-is measured directly by means of coherent Raman scattering...
September 30, 2016: Physical Review Letters
Stephen O Evans, Michael B Jameson, Ray T M Cursons, Linda M Peters, Steve Bird, Gregory M Jacobson
DNA damage quantitation assays such as the comet assay have focused on the measurement of total nuclear damage per cell. The adoption of PCR-based techniques to quantify DNA damage has enabled sequence- and organelle-specific assessment of DNA lesions. Here we report on an adaptation of a qPCR technique to assess DNA damage in nuclear and mitochondrial targets relative to control. Novel aspects of this assay include application of the assay to the Rotor-Gene platform with optimized DNA polymerase/fluorophore/primer set combination in a touchdown PCR protocol...
October 8, 2016: Biology
Tomohiko G Sano, Kiyoshi Kanazawa, Hisao Hayakawa
This study numerically and analytically investigates the dynamics of a rotor under viscous or dry friction as a nonequilibrium probe of a granular gas. In order to demonstrate the role of the rotor as a probe for a nonequilibrium bath, the molecular dynamics (MD) simulation of the rotor is performed under viscous or dry friction surrounded by a steady granular gas under gravity. A one-to-one map between the velocity distribution function (VDF) of the granular gas and the angular distribution function for the rotor is theoretically derived...
September 2016: Physical Review. E
Lauren Peruffo, Janice D Boyd, Sharman Hoppes, Donald J Brightsmith
Blood biochemical values are useful as indicators of disease in veterinary practice and for health assessments of free-ranging animal populations. We analyzed blood biochemical values for free-living nestling and adult scarlet macaws ( Ara macao macao) in southeastern Peru with an Abaxis VetScan VS2 portable analyzer with Avian/Reptilian Profile Plus rotors. The resulting data were used to create provisional age-independent reference intervals for this instrument for wild scarlet macaw nestlings, calculate blood biochemical ranges for this instrument for wild adults, and examine age-related trends in nestlings...
September 2016: Journal of Avian Medicine and Surgery
Tomislav Suhina, Saeed Amirjalayer, Benedetta Mennucci, Sander Woutersen, Michiel Hilbers, Daniel Bonn, Albert Manfred Brouwer
The fluorescence intensity of molecular rotors containing the dicyanomethylenedihydrofuran (DCDHF) motif increases strongly with solvent viscosity. Single-bond and double-bond rotations have been proposed as pathways of non radiative decay for this and related molecular rotors. We show here that both are involved in the case of DCDHF rotors: fluorescence is quenched by rotation around the dicyanomethylene double bond in non polar solvents, but in a sufficiently polar environment rotation about a formally single bond leads to a dark internal charge transfer state...
October 13, 2016: Journal of Physical Chemistry Letters
Abraham Colin-Molina, Salvador Pérez-Estrada, Arian E Roa, Alvin Villagrana-Garcia, Simón Hernández-Ortega, Mario Rodríguez, Stuart E Brown, Braulio Rodríguez-Molina
Liquid-like dynamics of a covalent 1,4-phenylene rotator have been unveiled in 1 with a brominated stator showing type-II halogen bonds. This singular rotation is favored by synergistic molecular changes in stacked molecules, according to VT solid state NMR, (1)H T1 relaxometry and VT X-ray experiments of this highly crystalline compound.
October 3, 2016: Chemical Communications: Chem Comm
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"