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https://www.readbyqxmd.com/read/29090253/fiberoptic-bronchoscope-and-c-mac-video-laryngoscope-assisted-nasal-oral-tube-exchange-two-case-reports
#1
Sungmi Ji, Jaegyok Song, Seok Kon Kim, Moon-Young Kim, Sangyun Kim
In cases of multiple facial trauma and other specific cases, the anesthesiologist may be asked to convert an oral endotracheal tube to a nasal endotracheal tube or vice versa. Conventionally, the patient is simply extubated and the endotracheal tube is re-inserted along either the oral or nasal route. However, the task of airway management can become difficult due to surgical trauma or worsening of the airway condition. Fiberoptic bronchoscopy was considered a novel method of airway conversion but this method is not useful when there are secretions and bleeding in the airway, or if the anesthesiologist is inexperienced in using this device...
September 2017: J Dent Anesth Pain Med
https://www.readbyqxmd.com/read/29079376/validation-of-the-troponin-only-manchester-acute-coronary-syndromes-decision-aid-with-a-contemporary-cardiac-troponin-i-assay
#2
Patricia Va Den Berg, Gillian Burrows, Philip Lewis, Simon Carley, Richard Body
OBJECTIVES: The Manchester Acute Coronary Syndromes (MACS) decision aid can 'rules in' and 'rule out' acute coronary syndromes (ACS) by combining a patient's symptoms with the results of a single blood test taken at the time of arrival in the Emergency Department (ED). The original model (MACS) included two biomarkers: high sensitivity cardiac troponin T (hs-cTnT) and heart-type fatty acid binding protein (h-FABP). A refined model without h-FABP was found to have comparable sensitivity but greater specificity...
September 23, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29048524/krait-an-ultrafast-tool-for-genome-wide-survey-of-microsatellites-and-primer-design
#3
Lianming Du, Chi Zhang, Qin Liu, Xiuyue Zhang, Bisong Yue
Summary: Microsatellites are found to be related with various diseases and widely used in population genetics as genetic markers. However, it remains a challenge to identify microsatellite from large genome and screen microsatellites for primer design from a huge result dataset. Here, we present Krait, a robust and flexible tool for fast investigation of microsatellites in DNA sequences. Krait is designed to identify all types of perfect or imperfect microsatellites on a whole genomic sequence, and is also applicable to identification of compound microsatellites...
October 18, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29047393/the-human-behaviour-change-project-harnessing-the-power-of-artificial-intelligence-and-machine-learning-for-evidence-synthesis-and-interpretation
#4
Susan Michie, James Thomas, Marie Johnston, Pol Mac Aonghusa, John Shawe-Taylor, Michael P Kelly, Léa A Deleris, Ailbhe N Finnerty, Marta M Marques, Emma Norris, Alison O'Mara-Eves, Robert West
BACKGROUND: Behaviour change is key to addressing both the challenges facing human health and wellbeing and to promoting the uptake of research findings in health policy and practice. We need to make better use of the vast amount of accumulating evidence from behaviour change intervention (BCI) evaluations and promote the uptake of that evidence into a wide range of contexts. The scale and complexity of the task of synthesising and interpreting this evidence, and increasing evidence timeliness and accessibility, will require increased computer support...
October 18, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29045448/interferon-free-therapy-with-direct-acting-antivirals-for-hcv-hiv-1-co-infected-japanese-patients-with-inherited-bleeding-disorders
#5
Haruka Uemura, Kunihisa Tsukada, Daisuke Mizushima, Takahiro Aoki, Koji Watanabe, Ei Kinai, Katsuji Teruya, Hiroyuki Gatanaga, Yoshimi Kikuchi, Masaya Sugiyama, Masashi Mizokami, Shinichi Oka
INTRODUCTION: Almost 30 years ago, about 30% of Japanese hemophiliacs became infected with HIV-1 and hepatitis C virus (HCV) after receiving contaminated blood products. While several studies have reported the high efficacy and safety of direct acting antivirals (DAA) in HIV-1 co-infected patients, such data are limited in hemophiliacs. METHODS: We conducted a single-center, open-label study involving 27 Japanese patients (median age; 45 years) with inherited bleeding disorders who were co-infected with HCV/HIV-1...
2017: PloS One
https://www.readbyqxmd.com/read/29042494/insights-from-the-genome-sequence-of-mycobacterium-lepraemurium-massive-gene-decay-and-reductive-evolution
#6
Andrej Benjak, Tanvi P Honap, Charlotte Avanzi, Enrique Becerril-Villanueva, Iris Estrada-García, Oscar Rojas-Espinosa, Anne C Stone, Stewart T Cole
Mycobacterium lepraemurium is the causative agent of murine leprosy, a chronic, granulomatous disease similar to human leprosy. Due to the similar clinical manifestations of human and murine leprosy and the difficulty of growing both bacilli axenically, Mycobacterium leprae and M. lepraemurium were once thought to be closely related, although it was later suggested that M. lepraemurium might be related to Mycobacterium avium In this study, the complete genome of M. lepraemurium was sequenced using a combination of PacBio and Illumina sequencing...
October 17, 2017: MBio
https://www.readbyqxmd.com/read/29036546/crocoblast-running-blast-efficiently-in-the-age-of-next-generation-sequencing
#7
Ravi José Tristão Ramos, Allan Cézar de Azevedo Martins, Gabrielle da Silva Delgado, Crina-Maria Ionescu, Turán Peter Ürményi, Rosane Silva, Jaroslav Koca
Summary: CrocoBLAST is a tool for dramatically speeding up BLAST+ execution on any computer. Alignments that would take days or weeks with NCBI BLAST+ can be run overnight with CrocoBLAST. Additionally, CrocoBLAST provides features critical for NGS data analysis, including: results identical to those of BLAST+; compatibility with any BLAST+ version; real-time information regarding calculation progress and remaining run time; access to partial alignment results; queueing, pausing, and resuming BLAST+ calculations without information loss...
November 15, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29036531/spatkin-a-simulator-for-rule-based-modeling-of-biomolecular-site-dynamics-on-surfaces
#8
Marek Kochanczyk, William S Hlavacek, Tomasz Lipniacki
Summary: Rule-based modeling is a powerful approach for studying biomolecular site dynamics. Here, we present SPATKIN, a general-purpose simulator for rule-based modeling in two spatial dimensions. The simulation algorithm is a lattice-based method that tracks Brownian motion of individual molecules and the stochastic firing of rule-defined reaction events. Because rules are used as event generators, the algorithm is network-free, meaning that it does not require to generate the complete reaction network implied by rules prior to simulation...
November 15, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29030039/effect-of-acidic-and-enzymatic-pretreatment-on-the-analysis-of-mountain-tea-sideritis-spp-volatiles-via-distillation-and-ultrasound-assisted-extraction
#9
Virginia D Dimaki, Gregoris Iatrou, Fotini N Lamari
A number of beneficial medicinal properties are attributed to the extract and essential oil of the aerial parts of Sideritis species (Lamiaceae). Hydrodistillation of the aerial parts of wild Sideritis clandestina ssp. peloponnesiaca (an endemic taxon in northern Peloponnesus, Greece) gave a low essential oil yield (<0.12%); about 65 components, mainly α-pinene, β-caryophyllene, β-pinene, globulol, caryophyllene oxide, were identified via GC-MS. Internal and external standards were used for quantification...
October 6, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29024106/nutritional-evaluation-of-the-legume-macrotyloma-axillare-using-in-vitro-and-in-vivo-bioassays-in-sheep
#10
P M T Lima, G D Moreira, G Z Sakita, A S Natel, W T Mattos, F M A Gimenes, L Gerdes, C McManus, A L Abdalla, H Louvandini
This study consisted of two experiments with the following objectives: to evaluate the effects of tannins from the tropical legume macrotiloma (Macrotyloma axillare) on total gas and methane (CH4 ) production, as well as on ruminal fermentation parameters by performing an in vitro bioassay, with samples incubated with and without polyethylene glycol (PEG) in a semi-automatic system; and secondly in a 17 day in vivo experiment, to determine apparent total tract digestibility (ATTD) of dietary nutrients and ruminal fermentation parameters of 12 intact 8- to 9-month-old Santa Inês (averaging 24...
October 10, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29021506/computational-wave-dynamics-for-innovative-design-of-coastal-structures
#11
Hitoshi Gotoh, Akio Okayasu
For innovative designs of coastal structures, Numerical Wave Flumes (NWFs), which are solvers of Navier-Stokes equation for free-surface flows, are key tools. In this article, various methods and techniques for NWFs are overviewed. In the former half, key techniques of NWFs, namely the interface capturing (MAC, VOF, C-CUP) and significance of NWFs in comparison with the conventional wave models are described. In the latter part of this article, recent improvements of the particle method are shown as one of cores of NWFs...
2017: Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
https://www.readbyqxmd.com/read/29017528/first-case-of-mycobacterium-marseillense-lymphadenitis-in-a-child
#12
A Azzali, C Montagnani, M T Simonetti, G Spinelli, M de Martino, L Galli
BACKGROUND: Nontuberculous mycobacteria (NTM) are pathogens that commonly affect the paediatric population and its most frequent manifestation is a cervicofacial lymphadenopathy. With the improvement of technologies, new species have been recently identified. CASE PRESENTATION: We report the first case of NMT lymphadenitis in a child caused by Mycobacterium marseillense, a newly described species belonging to Mycobacterium avium complex. CONCLUSIONS: Improving the identification of these newly discovered mycobacteria, further information will be available about their clinical involvement and their best treatment...
October 10, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28990865/effects-of-physical-randomness-training-on-virtual-and-laboratory-golf-putting-performance-in-novices
#13
T C Pataky, P F Lamb
External randomness exists in all sports but is perhaps most obvious in golf putting where robotic putters sink only 80% of 5 m putts due to unpredictable ball-green dynamics. The purpose of this study was to test whether physical randomness training can improve putting performance in novices. A virtual random-physics golf-putting game was developed based on controlled ball-roll data. Thirty-two subjects were assigned a unique randomness gain (RG) ranging from 0.1 to 2.0-times real-world randomness. Putter face kinematics were measured in 5 m laboratory putts before and after five days of virtual training...
October 9, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28984799/reply-to-comparing-c-mac-videolaryngoscope-with-direct-laryngoscopy-for-emergency-intubation
#14
Kurt Ruetzler, Simon Sulser, Dirk Ubmann, Donat R Spahn
No abstract text is available yet for this article.
November 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28984798/comparing-c-mac-videolaryngoscope-with-direct-laryngoscopy-for-emergency-intubation
#15
Ya-Yang Liu, Fu-Shan Xue, Hui-Xian Li, Gui-Zhen Yang
No abstract text is available yet for this article.
November 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28984546/mycobacterium-grossiae-sp-nov-a-rapidly-growing-scotochromogenic-species-isolated-from-human-clinical-respiratory-and-blood-culture-specimens
#16
Alberto Enrique Paniz-Mondolfi, Alexander L Greninger, Lynn Ladutko, Barbara A Brown-Elliott, Ravikiran Vasireddy, Wesley Jakubiec, Sruthi Vasireddy, Richard J Wallace, Keith E Simmon, Bruce E Dunn, Gary Jackoway, Surabhi B Vora, Kevin K Quinn, Xuan Qin, Sheldon Campbell
A previously undescribed, rapidly growing, scotochromogenic species of the genus Mycobacterium (represented by strains PB739(T) and GK) was isolated from two clinical sources - the sputum of a 76-year-old patient with severe chronic obstructive pulmonary disease, history of tuberculosis exposure and Mycobacterium avium complex isolated years prior; and the blood of a 15-year-old male with B-cell acute lymphoblastic leukaemia status post bone marrow transplant. The isolates grew as dark orange colonies at 25-37 °C after 5 days, sharing features in common with other closely related species...
October 6, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28976458/evaluation-of-the-c-mac-miller-video-laryngoscope-sizes-0-and-1-during-tracheal-intubation-of-infants-less-than-10-kg
#17
Florian J Raimann, Colleen E Cuca, Detlev Kern, Kai Zacharowski, Udo Rolle, Dirk Meininger, Christian F Weber, Christian Byhahn, Haitham Mutlak
STUDY OBJECTIVE: Video laryngoscopy has primarily been developed to assist in difficult airways. Using video laryngoscopy in pediatric airway management is an up-and-coming topic. The aim of the presented study was to compare the intubation conditions obtained when using the C-MAC video laryngoscope with Miller blades sizes 0 and 1 for standard direct laryngoscopy and indirect laryngoscopy in children weighing less than 10 kg. DESIGN: This was a prospective study...
October 2, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28971804/a-randomised-trial-to-compare-truview-pcd-%C3%A2-c-mac-%C3%A2-and-macintosh-laryngoscopes-in-paediatric-airway-management
#18
Ranju Singh, Nishant Kumar, Aruna Jain
AIM: To evaluate and compare the Truview PCD and C-MAC laryngoscopes to the standard Macintosh laryngoscope in paediatric patients. METHODS: One hundred and fifty ASA I-II patients in the age group of 1-6 years (10-20 kg) scheduled for elective surgery were randomised into three equal groups for laryngoscopy and intubation with either Truview PCD (Group T), C-MAC (Group C) or Macintosh (Group M) laryngoscopes under general anaesthesia. Percentage of glottic opening (POGO) score, application of external laryngeal manoeuvre, time to intubation, number of attempts at intubation, failed intubations, episodes of desaturation and trauma caused were recorded and statistically analysed...
June 2017: Asian J Anesthesiol
https://www.readbyqxmd.com/read/28963547/efficient-adsorption-of-sulfamethazine-onto-modified-activated-carbon-a-plausible-adsorption-mechanism
#19
Ying Liu, Xiaohui Liu, Wenping Dong, Lingli Zhang, Qiang Kong, Weiliang Wang
Activated carbon (AC) was modified by FeCl3. Batch experiments were carried out to evaluate the characteristics of equilibrium, kinetics and thermodynamics of Sulfamethazine adsorption onto original and modified AC. The results showed that Fe(3+) treatment changed the surface area, pore volume and surface zeta potential and increased the number of surface oxygenic functional groups. The adsorption of Sulfamethazine on modified activated carbon (MAC) was significantly improved. Isotherm test results revealed that the adsorption isotherms of Sulfamethazine on MAC fit the Freundlich, Langmuir and Temkin equations well...
September 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28954531/is-off-clamp-always-beneficial-during-robotic-partial-nephrectomy-a-propensity-score-matched-comparison-of-clamp-technique-in-patients-with-two-kidneys
#20
Daniel C Rosen, David J Paulucci, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, Ketan K Badani
OBJECTIVE: The majority of patients undergoing partial nephrectomy (PN) present with a clinical T1a tumor with both kidneys present. Some groups have advocated using off-clamp (Off-C) techniques to eliminate warm ischemia whenever possible, even when elective. We evaluated whether Off-C technique during robotic PN (RPN) provides any functional benefit over main arterial clamping (MAC) in these patients. Subjects/Patients and Methods: A total of 351 patients with a R.E.N.A.L. nephrometry score (RNS) <10, T1a tumor, and two kidneys who underwent RPN from five high-volume surgeons between 2008 and 2016 were retrospectively identified from a multi-institutional database...
November 2017: Journal of Endourology
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