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https://www.readbyqxmd.com/read/29924134/association-between-serotonin-2c-receptor-gene-htr2c-polymorphisms-and-psychopathological-symptoms-in-children-and-adolescents
#1
L A Paes, O H Della Torre, T B Henriques, M P de Mello, E H R V Celeri, P Dalgalarrondo, G Guerra Júnior, A Dos Santos Júnior
Serotonin 2C receptors (5HT2C) are involved in serotonin-driven dynamic equilibrium adjustments responsible for homeostatic stability in brain structures that modulate behavior and emotions. Single nucleotide polymorphisms (SNPs) from the serotonin 2C receptor gene (HTR2C) have been associated with several neurological and mental disorders, including abnormalities in cognitive and emotional processes. The aim of this study was to evaluate the association between the rs6318 SNP of the HTR2C gene and behavioral characteristics exhibited by children and adolescents based on the Child Behavior Checklist (CBCL/6-18) inventory...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29904907/systematic-review-and-guide-to-management-of-core-and-psychiatric-symptoms-in-youth-with-autism
#2
REVIEW
S H Ameis, C Kassee, P Corbett-Dick, L Cole, S Dadhwal, M-C Lai, J Veenstra-VanderWeele, C U Correll
OBJECTIVE: Evidence-based guidance of clinical decision-making for the management of Autism Spectrum Disorder (ASD) is lacking, particularly for co-occurring psychiatric symptoms. This review evaluates treatment evidence for six common symptom targets in children/adolescents with ASD and provides a resource to facilitate application of the evidence to clinical practice. METHOD: A systematic search identified randomized controlled trials (RCTs) and high-quality systematic reviews published between 2007 and 2016, focused on: social interaction/communication impairment, stereotypic/repetitive behaviours, irritability/agitation, attention-deficit/hyperactivity disorder symptoms, mood or anxiety symptoms, and sleep difficulties...
June 14, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29886327/is-growth-hormone-deficiency-associated-with-anxiety-disorder-and-depressive-symptoms-in-children-and-adolescents-a-case-control-study
#3
İsmail Akaltun, Atilla Çayır, Tayfun Kara, Hamza Ayaydın
AIM: Children with growth hormone deficiency (GHD) are reported to experience failure in psychological maturation, and to have a lack of self-confidence in social life, and depressive symptoms. The purpose of this study was to investigate the relation between GHD and anxiety disorders and depression in children and adolescents. METHOD: 122 children and adolescents aged 7-17, 87 receiving GHD therapy and 35 before treatment, and 122 healthy volunteers were included in the study...
June 4, 2018: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/29882272/survey-of-the-european-psychiatric-association-on-the-european-status-and-perspectives-in-early-detection-and-intervention-in-at-risk-mental-state-and-first-episode-psychosis
#4
Nadja P Maric, Sanja Andric Petrovic, Andrea Raballo, Martina Rojnic-Kuzman, Joachim Klosterkötter, Anita Riecher-Rössler
AIM: Early detection/early intervention (ED/EI) programmes have been inconsistently implemented throughout Europe. We evaluated the ED/EI service distribution in European Psychiatric Association (EPA) member countries, considering indicators of socio-economic development, human and financial resources allocated in mental health (MH) as well as presence of a national branch of the Early Intervention in MH (IEPA). Contextually, we evaluated the duration of untreated psychosis (DUP) in relation to ED/EI service implementation...
June 8, 2018: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29882037/psychotropic-usage-by-patients-presenting-to-an-academic-eating-disorders-program
#5
Karuna Mizusaki, Daniel Gih, Christina LaRosa, Rebekah Richmond, Renee D Rienecke
PURPOSE: To assess psychotropic use patterns and possible associations with age, eating disorder diagnosis and psychiatric comorbidity in adolescents and young adults with a primary eating disorder. METHODS: A retrospective chart review of 86 consecutive patients with a primary eating disorder from August 2012 to December 2014 was conducted. Patients presented for a multidisciplinary evaluation at a United States-based academic program for eating disorders. RESULTS: Nearly half (45...
June 7, 2018: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29858452/psychiatric-diagnoses-and-weight-loss-among-adolescents-receiving-sleeve-gastrectomy
#6
Eleanor R Mackey, Jichuan Wang, Chloe Harrington, Evan P Nadler
BACKGROUND AND OBJECTIVES: Severe obesity is associated with higher risk of psychiatric difficulties. Bariatric surgery is the most effective treatment of severe obesity. Few guidelines exist regarding the association of psychiatric diagnoses in adolescents and outcomes after surgery because of the lack of longitudinal research. Our objective is to evaluate the rates of psychiatric diagnoses in adolescents undergoing surgery compared with those not receiving surgery and the association of preoperative psychiatric diagnoses with postsurgical weight loss outcomes...
June 1, 2018: Pediatrics
https://www.readbyqxmd.com/read/29845514/examination-of-a-board-game-approach-to-children-s-involvement-in-family-based-weight-management-vs-traditional-family-based-behavioral-counseling-in-primary-care
#7
Merve Sen, Arzu Uzuner, Mehmet Akman, Aliye Tugba Bahadir, Nazire Oncul Borekci, Emanuela Viggiano
The most effective intervention model for childhood obesity is known as family-based behavioral group treatments. There are also studies that investigate the effects of educational games for children to gain healthy eating and physical exercise habits. The aim of this study was to compare the efficacy of a family-based group treatment with an educational game (Kaledo) intervention in childhood obesity. Kaledo is a board game that was designed to improve nutritional knowledge and healthy life style habits. It is played with nutrition and activity cards that players can select from, and a total score is calculated in the end of the game according to energy intake and expenditure...
May 29, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29802465/the-effect-of-deformity-correction-on-psychiatric-condition-of-the-adolescent-with-adolescent-idiopathic-scoliosis
#8
Altuğ Duramaz, Semra Yılmaz, Nezih Ziroğlu, Burcu Bursal Duramaz, Tayfun Kara
PURPOSE: The purpose of this prospective study was to evaluate the effects of deformity correction on body image, quality of life, self-esteem, depression and anxiety in patients with adolescent idiopathic scoliosis (AIS) who underwent surgery. METHODS: Between June 2014 and July 2015, 41 consecutive patients who underwent surgery for AIS were compared with the control group of 52 healthy patients regarding the changes in the pre- and postoperative quality of life and psychiatric status of patients with deformity correction...
May 25, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29789273/insulin-resistance-is-related-to-psychiatric-disorders-among-obese-children
#9
Deniz Özalp Kızılay, Şermin Yalın Sapmaz, Semra Şen, Yekta Özkan, Betül Ersoy
OBJECTIVE: The current study aimed to investigate psychiatric consequences of obesity (OBy) and the relationship between metabolic syndrome components and psychiatric disorders in children. Our secondaryaim was to elucidate which of the anthropometric parameters or metabolic components were most strongly associated with psychiatric disorders. METHODS: The study included 88 obese(OB)and overweight (OW) children with a body mass index (BMI) greater than 85th percentile...
May 23, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29777605/ethics-and-or-aesthetics-reflections-on-cosmetic-surgery-for-adolescents
#10
Gianluca Montanari Vergallo, Enrico Marinelli, Simona Napoletano, Natale Mario Di Luca, Simona Zaami
Cosmetic surgery entails various ethical issues, even more so in cases involving adolescent patients. Cosmetic surgeons need to take into account how modern societies consider physical appearance an essential component of everyday life, as well as the vulnerability of youths and adolescents. For that reason, it is imperative to thoroughly assess the psychological and emotional states, in addition to the motivations, of minor patients. That goal can be achieved through the use of the DAS-59, (the Derriford Appearance Scale)1 , an effective and dependable tool devised to evaluate the psychological difficulties and distress experienced by people living with problems of appearance...
May 2018: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/29768038/use-and-characteristics-of-antipsychotic-methylphenidate-combination-therapy-in-children-and-adolescents-with-a-diagnosis-of-attention-deficit-hyperactivity-disorder
#11
Oliver Scholle, Tobias Banaschewski, Dirk Enders, Edeltraut Garbe, Oliver Riedel
OBJECTIVE: Children and adolescents with attention-deficit/hyperactivity disorder (ADHD) frequently have comorbidities that are potential indications for antipsychotics (APs). Some studies have suggested that the combined use of methylphenidate (MPH) and APs is increasing in this population group. Longitudinal analyses and in-depth investigations on the substance level are lacking. This study aimed to estimate the cumulative proportion of concomitant AP/MPH use in children and adolescents with ADHD over a follow-up of up to 9 years and to describe patient characteristics stratified by specific AP drug...
May 16, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29753993/reliability-of-neural-activation-and-connectivity-during-implicit-face-emotion-processing-in-youth
#12
Simone P Haller, Katharina Kircanski, Joel Stoddard, Lauren K White, Gang Chen, Banafsheh Sharif-Askary, Susan Zhang, Kenneth E Towbin, Daniel S Pine, Ellen Leibenluft, Melissa A Brotman
Face emotion imaging paradigms are widely used in both healthy and psychiatric populations. Here, in children and adolescents, we evaluate the test-retest reliability of blood oxygenation-level dependent (BOLD) activation and task-based functional connectivity on a widely used implicit face emotion processing task (i.e., gender labeling). Twenty-five healthy youth (M age = 13.97 year s; 60% female) completed two functional magnetic resonance imaging (fMRI) scan sessions approximately two months apart...
March 27, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29734102/low-doses-of-methylmercury-intoxication-solely-or-associated-to-ethanol-binge-drinking-induce-psychiatric-like-disorders-in-adolescent-female-rats
#13
Ivaldo Jesus Almeida Belém-Filho, Paula Cardoso Ribera, Aline Lima Nascimento, Antônio Rafael Quadros Gomes, Rafael Rodrigues Lima, Maria Elena Crespo-Lopez, Marta Chagas Monteiro, Enéas Andrade Fontes-Júnior, Marcelo Oliveira Lima, Cristiane Socorro Ferraz Maia
Methylmercury (MeHg) is an environmental contaminant that provokes damage to developing brain. Simultaneously, the consumption of ethanol among adolescents has increased. Evidence concerning the effects of MeHg low doses per se or associated with ethanol during adolescence are scarce. Thus, we investigate behavioral disorders resulted from exposure to MeHg low doses and co-intoxicated with ethanol in adolescent rats. Wistar rats received chronic exposure to low doses of MeHg (40 μg/kg/day for 5 weeks) and/or ethanol binge drinking (3 g/kg/day at 3 days per week for 5 weeks)...
April 30, 2018: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29730872/neuropeptide-y-levels-in-children-and-adolescents-with-attention-deficit-hyperactivity-disorder
#14
Özlem Hekim Bozkurt, Esra Güney, Zeynep Göker, Gülser Şenses Dinç, Murat Alışık, Özcan Erel, Esra Çöp, Özden Şükran Üneri
OBJECTIVE: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in adolescence, however, the etiology has not been described. Neuropeptide Y (NPY) is one potential factor that may be involved in the etiology of ADHD. The goal of this study was to evaluate NPY levels in children with ADHD and compare the findings to healthy controls. METHODS: Forty-eight ADHD patients and 40 healthy controls were included in this study. The age range of ADHD patients was 6 to 16 years...
2018: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
https://www.readbyqxmd.com/read/29728981/quality-of-life-and-satisfaction-with-inpatient-treatment-in-adolescents-with-psychiatric-disorders-a-comparison-between-patients-parents-and-caregivers-self-assessments-at-admission-and-discharge
#15
Petra Katzenschläger, Rainer Fliedl, Christian Popow, Michael Kundi
OBJECTIVES: The purpose of this study was to compare results of patients', parents', and caregivers' (nursing staff and educators) (self-)assessments of quality of life, treatment outcomes, and satisfaction with inpatient treatment in a child and adolescent psychiatric hospital. In addition, the investigation included a comparison between admission and discharge of the three investigated groups. METHODS: The study considered adolescents at the Department of Child and Adolescent Psychiatry and Psychotherapy, Hinterbruehl, along with their parents and caregivers...
May 4, 2018: Neuropsychiatrie: Klinik, Diagnostik, Therapie und Rehabilitation
https://www.readbyqxmd.com/read/29685560/high-rates-of-psychiatric-disorders-and-below-normal-mental-capacity-associated-with-spastic-peroneal-flatfoot-a-new-relationship
#16
Önder İsmet Kılıçoğlu, Ahmet Salduz, Fevzi Birişik, Fuat Bilgili, Gökhan Polat, İlyas Kaya, Funda Süleyman, Murat Coşkun
Spastic peroneal flatfoot (SPFF) is a rare hindfoot pathology usually seen in the adolescent age group that is characterized by painful spasms in the peroneal muscles. We have clinically observed that patients with SPFF also have some behavioral and emotional difficulties and problems in their academic achievements. Because of these observations, we investigated the prevalence and patterns of psychiatric disorders and intellectual disability among young subjects with SPFF. Our cohort consisted of 16 patients with SPFF...
May 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29665518/early-intervention-for-adolescents-at-risk-for-bipolar-disorder-a-pilot-randomized-trial-of-interpersonal-and-social-rhythm-therapy-ipsrt
#17
Tina R Goldstein, John Merranko, Megan Krantz, Matthew Garcia, Peter Franzen, Jessica Levenson, David Axelson, Boris Birmaher, Ellen Frank
OBJECTIVE: To conduct a pilot randomized trial of Interpersonal and Social Rhythm Therapy plus Data-Informed Referral (IPSRT + DIR) versus DIR-alone for adolescents at-risk for bipolar disorder (BP). METHOD: Eligible participants included youth (12-18) with a BP parent; youth with BP were excluded. Participants (n = 42) were randomized to receive IPSRT + DIR to treat any psychiatric disorders present at baseline, or DIR-alone. A blind evaluator assessed outcomes at baseline, 3- and 6-months...
August 1, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29659203/a-qualitative-study-to-assess-how-primary-care-versus-psychiatric-providers-evaluate-and-treat-pediatric-patients-with-irritability
#18
Anna L Scandinaro, Usman Hameed, Cheryl A Dellasega
Objective: To determine how primary care versus specialist practitioners assess and treat school-aged children with irritability. Methods: Seventeen providers from family medicine, pediatrics, and psychiatry participated in in-depth interviews from June to August 2016 about the process they use to evaluate irritability. Data on demographic traits and measures of confidence were also collected. Results: Primary care (family medicine and pediatrics) participants expressed frustration over the lack of time and specialized knowledge they had to accurately assess children with irritability, even though they were often the first clinician consulted when problems arose...
April 5, 2018: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/29656036/laparoscopic-adjustable-gastric-banding-in-adolescents-with-severe-obesity-psychological-aspects-decision-makers-of-surgery-and-2-year-outcomes-a-case-series
#19
E Riquin, F Schmitt, N Bouhours-Nouet, M Beaumesnil, M Dinomais, J Malka, M Robin, R Coutant, P Duverger
BACKGROUND: The results of medical treatment of severe obesity in the adolescent population (balanced diet and physical activity) are often unsatisfactory, and bariatric surgery is questioned. The psychological determinants for requesting bariatric surgery in these adolescents are unclear. The objective of this study was to report the psychiatric and psychological aspects as well as the determinants of the medical decision for surgery in a cohort of obese adolescents requesting bariatric surgery by laparoscopic adjustable gastric banding...
May 2018: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/29655375/association-between-traumatic-stress-load-psychopathology-and-cognition-in-the-philadelphia-neurodevelopmental-cohort
#20
Ran Barzilay, Monica E Calkins, Tyler M Moore, Daniel H Wolf, Theodore D Satterthwaite, J Cobb Scott, Jason D Jones, Tami D Benton, Ruben C Gur, Raquel E Gur
BACKGROUND: Traumatic stressors during childhood and adolescence are associated with psychopathology, mostly studied in the context of post-traumatic stress disorder (PTSD) and depression. We investigated broader associations of traumatic stress exposure with psychopathology and cognition in a youth community sample. METHODS: The Philadelphia Neurodevelopmental Cohort (N = 9498) is an investigation of clinical and neurobehavioral phenotypes in a diverse (56% Caucasian, 33% African American, 11% other) US youth community population (aged 8-21)...
April 15, 2018: Psychological Medicine
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