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https://www.readbyqxmd.com/read/28228789/long-term-outcome-of-grade-iii-and-iv-chondral-injuries-of-the-knee-treated-with-steadman-microfracture-technique
#1
Marco Pellegrino, Ermanno Trinchese, Michele Bisaccia, Giuseppe Rinonapoli, Luigi Meccariello, Gabriele Falzarano, Antonio Medici, Luigi Piscitelli, Pellegrino Ferrara, Auro Caraffa
INTRODUCTION: The aim of our study is to demonstrate the effectiveness of Steadman microfracture technique in the management of high-grade chondral defects at the level of the knee by clinical follow-ups at eleven years. MATERIALS AND METHODS: This is a study conducted on fifteen patients suffering from Outerbridge grade III and IV chondral lesions of the knee, who underwent Steadman microfracture surgery between 2003 and 2004. Selective exclusion criteria to prevent that other treatments or comorbidities could invalidate the results were used...
September 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/28224070/combined-particulated-juvenile-cartilage-allograft-transplantation-and-medial-patellofemoral-ligament-reconstruction-for-symptomatic-chondral-defects-in-the-setting-of-recurrent-patellar-instability
#2
Armin Arshi, Dean Wang, Kristofer J Jones
Successful management of patellar osteochondral lesions has proved difficult, with unreliable outcomes reported using traditional cartilage repair and restoration procedures. Unique considerations for this type of defect include the multiplanar contours of the articular surface of the patella, high compressive and shear forces with knee range of motion that may disrupt graft healing, and the potential need for concomitant surgery to address patellar malalignment and instability. We describe our preferred method for treatment of a symptomatic chondral defect in the setting of recurrent patellar instability using particulated juvenile articular cartilage allograft transplantation and medial patellofemoral ligament reconstruction with semitendinosus allograft...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28219360/interobserver-and-intraobserver-agreement-of-ligamentous-injuries-on-conventional-mri-after-simple-elbow-dislocation
#3
Marc Schnetzke, Svenja Schüler, Johannes Hoffend, Rainer Simon, Holger Keil, Felix Porschke, Stefan Studier-Fischer, Paul-Alfred Grützner, Thorsten Guehring
BACKGROUND: The primary objective of this study was to assess the interobserver and intraobserver agreement on ligamentous injuries on conventional magnetic resonance imaging (MRI) in acute simple elbow dislocation. The secondary objectives were to determine the interobserver agreement on the assessment of joint congruity, joint effusion, loose bodies and chondral lesions on conventional MRI. METHODS: Conventional MRIs (1.5 Tesla, elbow specific surface coil) of 30 patients (40...
February 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28210944/postoperative-imaging-in-arthroscopic-hip-surgery
#4
REVIEW
F Di Pietto, V Chianca, R de Ritis, E Cesarano, A Reginelli, A Barile, M Zappia, L Ginolfi
Arthroscopic surgery of the hip, compared to that of the knee or the shoulder, has only recently been developed in any significant way. Current indications for arthroscopic surgery of the hip include: diagnosis and treatment of lesions symptomatic of the acetabular labrum, femoroacetabular impingement (FAI), chondral lesions, joint infections, lesions of the teres ligament, impingement of the psoas tendon, pathology of the peritrochanteric space, external snapping hip (coxa saltans), and traumatic and atraumatic instability...
February 16, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28210226/combination-of-collagen-based-scaffold-and-bioactive-factors-induces-adipose-derived-mesenchymal-stem-cells-chondrogenic-differentiation-in-vitro
#5
Giovanna Calabrese, Stefano Forte, Rosario Gulino, Francesco Cefalì, Elisa Figallo, Lucia Salvatorelli, Eugenia T Maniscalchi, Giuseppe Angelico, Rosalba Parenti, Massimo Gulisano, Lorenzo Memeo, Raffaella Giuffrida
Recently, multipotent mesenchymal stem cells (MSCs) have attracted much attention in the field of regenerative medicine due to their ability to give rise to different cell types, including chondrocytes. Damaged articular cartilage repair is one of the most challenging issues for regenerative medicine, due to the intrinsic limited capability of cartilage to heal because of its avascular nature. While surgical approaches like chondral autografts and allografts provide symptoms and function improvement only for a short period, MSC based stimulation therapies, like microfracture surgery or autologous matrix-induced chondrogenesis demonstrate to be more effective...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28209142/accuracy-of-magnetic-resonance-studies-in-the-detection-of-chondral-and-labral-lesions-in-femoroacetabular-impingement-systematic-review-and-meta-analysis
#6
A M Saied, C Redant, M El-Batouty, M R El-Lakkany, W A El-Adl, J Anthonissen, R Verdonk, E A Audenaert
BACKGROUND: Several types of Magnetic resonance imaging (MRI) are commonly used in imaging of femoroacetabular impingement (FAI), however till now there are no clear protocols and recommendations for each type. The aim of this meta-analysis is to detect the accuracy of conventional magnetic resonance imaging (cMRI), direct magnetic resonance arthrography (dMRA) and indirect magnetic resonance arthrography (iMRA) in the diagnosis of chondral and labral lesions in femoroacetabular impingement (FAI)...
February 16, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28203047/transplantation-of-autologous-chondrocytes-ex-vivo-expanded-using-thermoreversible-gelation-polymer-in-a-rabbit-model-of-articular-cartilage-defect
#7
Sivaraman Arumugam, Balasubramanyan Bhupesh Karthik, Rajeswar Chinnuswami, Yuichi Mori, Hiroshi Yoshioka, Rajappa Senthilkumar, Rajmohan Mathaiyan, Karthick Ramalingam, Preethy Senthilkumar, Samuel J K Abraham
Graft failure due to de-differentiation of the chondrocytes during in vitro culture and after transplantation is a major hurdle in Autologous Chondrocyte Implantation (ACI). We, herein, report the transplantation of autologous chondrocytes ex vivo expanded using a Thermo-reversible Gelation Polymer (TGP) in a rabbit model. A full thickness chondral defect was created in one of the knee joints in each of the six rabbits of the study and autologous chondrocytes in vitro expanded using TGP scaffold were transplanted after 10 weeks...
June 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28193143/conscious-performance-and-arthroscopic-findings-in-athletes-with-anterior-cruciate-ligament-injuries-treated-via-conservative-therapy-during-the-competitive-season
#8
Yasushi Takata, Junsuke Nakase, Tatsuhiro Toratani, Hitoaki Numata, Takeshi Oshima, Katsuhiko Kitaoka, Hiroyuki Tsuchiya
PURPOSE: Athletes often receive conservative treatment for injured anterior cruciate ligaments (ACLs) so that they can continue to play to the end of their season. The purpose of this study was to examine the conscious performance and arthroscopic findings of athletes who received conservative therapy for ACL injuries. METHODS: Forty-two patients with ACL injuries underwent conservative treatment. After the season ended, ACL reconstruction was performed. We examined the following parameters: (1) time required for return to competition after injury, (2) conscious performance after return to competition, (3) whether the injured knee gave way during conservative therapy or after return to competition, and (4) cause of performance deterioration if applicable...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28185993/intracarpal-shortening-osteotomy-for-kienb%C3%A3-ck-s-disease-a-retrospective-study-of-28-cases
#9
Jérémie Chevrollier, Germain Pomares, Sandrine Huguet, François Dap, Gilles Dautel
INTRODUCTION: Kienböck's disease is rare in patients with a neutral or positive ulnar variance. In these situations, treatment is challenging and controversial.Various intracarpal shortening osteotomy (ICSO) procedures have been proposed. OBJECTIVE: Study the effect of the type of ICSO (isolated capitate osteotomy or combined with hamate osteotomy) on the clinical and radiological outcomes in a retrospective series. METHODS: Patients with Kienböck's disease were treated with ICSO...
February 6, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28176372/development-of-the-skull-and-pectoral-girdle-in-siberian-sturgeon-acipenser-baerii-and-russian-sturgeon-acipenser-gueldenstaedtii-acipenseriformes-acipenseridae
#10
Peter Warth, Eric J Hilton, Benjamin Naumann, Lennart Olsson, Peter Konstantinidis
The head is considered the major novelty of the vertebrates and directly linked to their evolutionary success. Its form and development as well as its function, for example in feeding, is of major interest for evolutionary biologists. In this study, we describe the skeletal development of the cranium and pectoral girdle in Siberian (Acipenser baerii) and Russian sturgeon (A. gueldenstaedtii), two species that are commonly farmed in aquaculture and increasingly important in developmental studies. This study comprises the development of the neuro-, viscero- and dermatocranium and the dermal and chondral components of the pectoral girdle, from first condensation of chondrocytes in prehatchlings to the early juvenile stage and reveals a clear pattern in formation...
February 7, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28170363/fixation-of-chondral-only-shear-fractures-of-the-knee-in-pediatric-and-adolescent-athletes
#11
Peter D Fabricant, Yi-Meng Yen, Dennis E Kramer, Mininder S Kocher, Lyle J Micheli, Benton E Heyworth
No abstract text is available yet for this article.
March 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28170184/regeneration-of-articular-cartilage-by-human-esc-derived-mesenchymal-progenitors-treated-sequentially-with-bmp-2-and-wnt5a
#12
Jason D Gibson, Michael B O'Sullivan, Farhang Alaee, David N Paglia, Ryu Yoshida, Rosa M Guzzo, Hicham Drissi
The success of cell-based therapies to restore joint cartilage requires an optimal source of reparative progenitor cells and tight control of their differentiation into a permanent cartilage phenotype. Bone morphogenetic protein 2 (BMP-2) has been extensively shown to promote mesenchymal cell differentiation into chondrocytes in vitro and in vivo. Conversely, developmental studies have demonstrated decreased chondrocyte maturation by Wingless-Type MMTV Integration Site Family, Member 5A (Wnt5a). Thus, we hypothesized that treatment of human embryonic stem cell (hESC)-derived chondroprogenitors with BMP-2 followed by Wnt5a may control the maturational progression of these cells into a hyaline-like chondrocyte phenotype...
January 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28169108/prevalence-and-clinical-significance-of-hypertrophic-labrum-in-non-dysplastic-hips
#13
Yong-Chan Ha, Young-Kyun Lee, Kyung-Hoi Koo, Ki-Bum Kwon, Sang-Heon Song
BACKGROUND: Hypertrophic labrum in dysplastic hip has been frequently reported and is known as limbus in developmental dysplasia of the hip. However, hypertrophic labrum without hip dysplasia has not been reported to date. The purpose of this study was to define hypertrophic labrum and to investigate the prevalence and clinical significance of an abnormally hypertrophic labrum in non-dysplastic hips. METHODS: Between 2007 and 2014, direct CT arthrography was performed in 464 patients (470 hips) who had chronic groin pain and positive impingement or Faber test...
February 3, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28164046/treatment-of-the-bullet-traversing-femoral-neck-lodged-in-hip-joint-initial-arthroscopic-removal-and-subsequent-cartilage-repair
#14
Mehmet Faruk Çatma, Serhan Ünlü, Önder Ersan, Alper Öztürk
INTRODUCTION: There have been several reports on arthroscopically assisted removal of the bullet imbedded in hip joint in the literature. Similarly, in this case, a bullet lodged in acetabulum was extracted with arthroscopic technique. What makes this case unique in the literature is that the bullet removed from the acetabulum traversed the femoral neck. CASE REPORT: Male patient aged 32 years with a low-velocity gunshot wound was referred to the emergency room on August 28, 2012...
September 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28162918/reliability-and-validity-of-the-arthroscopic-international-cartilage-repair-society-classification-system-correlation-with-histological-assessment-of-depth
#15
Tim Dwyer, C Ryan Martin, Rita Kendra, Corey Sermer, Jaskarndip Chahal, Darrell Ogilvie-Harris, Daniel Whelan, Lucas Murnaghan, Aaron Nauth, John Theodoropoulos
PURPOSE: To determine the interobserver reliability of the International Cartilage Repair Society (ICRS) grading system of chondral lesions in cadavers, to determine the intraobserver reliability of the ICRS grading system comparing arthroscopy and video assessment, and to compare the arthroscopic ICRS grading system with histological grading of lesion depth. METHODS: Eighteen lesions in 5 cadaveric knee specimens were arthroscopically graded by 7 fellowship-trained arthroscopic surgeons using the ICRS classification system...
February 2, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28162881/midterm-results-of-osteochondral-allograft-transplantation-to-the-humeral-head
#16
Andrew J Riff, Adam B Yanke, Jason J Shin, Anthony A Romeo, Brian J Cole
BACKGROUND: This study evaluated clinical outcomes of osteochondral allograft (OCA) transplantation for humeral head osteochondral defects. We hypothesized that patients with isolated humeral head disease would achieve favorable results and that patients with bipolar disease would experience inferior outcomes. METHODS: We identified patients who underwent humeral head OCA transplantation. Subjective questionnaire data were obtained preoperatively and at a minimum of 2 years postoperatively...
February 2, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28149742/endoscopic-calcaneoplasty-and-achilles-tendoscopy-with-the-patient-in-supine-position
#17
Tun Hing Lui
Insertional and non-insertional Achilles tendinopathy is usually treated conservatively. Surgery is indicated if conservative treatment fails to relieve the pain. Endoscopic surgery has the advantages of less morbidity, a shorter operating time, reduced postoperative pain, and a lower rate of wound and soft-tissue healing problems. Patients will have a short recovery time and quickly resume work and sports because of less soft-tissue disruption. Moreover, the pathology can be better differentiated and precisely treated...
December 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28146402/a-multicenter-study-of-early-anti-inflammatory-treatment-in-patients-with-acute-anterior-cruciate-ligament-tear
#18
Christian Lattermann, Cale A Jacobs, Mary Proffitt Bunnell, Laura J Huston, Lee G Gammon, Darren L Johnson, Emily K Reinke, Janet L Huebner, Virginia B Kraus, Kurt P Spindler
BACKGROUND: It is increasingly recognized that biochemical abnormalities of the joint precede radiographic abnormalities of posttraumatic osteoarthritis (PTOA) by as much as decades. A growing body of evidence strongly suggests that the progression from anterior cruciate ligament (ACL) injury to PTOA is multifactorial, involving the interplay between biomechanical disturbances and biochemical homeostasis of articular cartilage. PURPOSE: The purposes of this randomized study using an acute ACL injury model were to (1) evaluate the natural progression of inflammatory and chondrodegenerative biomarkers, (2) evaluate the relationship between subjective reports of pain and inflammatory and chondrodegenerative biomarkers, and (3) determine if postinjury arthrocentesis and corticosteroid injection offer the ability to alter this biochemical cascade...
February 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28131680/the-chondral-print-sign-what-does-it-really-mean
#19
Peter Domos, Devdatta S Neogi, Umile Giuseppe Longo, Philip M Ahrens
BACKGROUND: The chondral print (CP) sign is a chondral change on the humeral head underneath the long head of the biceps (LHB) tendon. Several suggested causative links have been described, but the pathologic mechanism remains unclear. METHODS: We designed this prospective cohort association study of 102 consecutive shoulder arthroscopies to investigate proposed associations of CP with LHB, rotator cuff, labral pathology, and other chondral lesions. Data collection was by a specifically designed pro forma, and statistical analysis was performed...
January 25, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28121366/the-use-of-vascularised-bone-capping-to-prevent-and-treat-amputation-stump-spiking-in-the-paediatric-population
#20
Adrian D Murphy, Sara E Atkins, Damon J Thomas, David McCombe, Chris J Coombs
BACKGROUND: Overgrowth of the stump skeleton is a major complication seen in children after an amputation. In advanced cases, perforation of the bone spike through the skin can occur. Many surgical treatments have been employed to treat and prevent this, with best results seen when non-vascularised osteo-chondral bone grafts are placed to try to mimic a trans-articular amputation. We reviewed our outcomes using vascularized bone flaps to prevent and treat spiking. PATIENTS AND METHODS: Between 2000 and 2016 we carried out six vascularised osteo-cartilaginous bone capping procedures...
January 25, 2017: Microsurgery
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