keyword
MENU ▼
Read by QxMD icon Read
search

Chondral

keyword
https://www.readbyqxmd.com/read/29780619/hip-arthroscopy-for-femoroacetabular-impingement
#1
Rima Nasser, Benjamin Domb
The purpose of this article is to give a general overview of femoroacetabular impingement (FAI) and how it could be treated arthroscopically, with some details about indications, the procedure itself and some of the complications associated with the surgery.FAI is a dynamic condition of the hip that can be a source of pain and disability and could potentially lead to arthritis.When symptomatic, and if conservative treatment fails, FAI can be addressed surgically.The goal of surgical treatment for FAI is to recreate the spherical contour of the femoral head, improve femoral offset, normalize coverage of the acetabulum, repair/reconstruct chondral damage and repair/reconstruct the labrum to restore normal mechanics and joint sealing...
April 2018: EFORT Open Reviews
https://www.readbyqxmd.com/read/29777422/patellofemoral-cartilage-repair
#2
REVIEW
Alexandre Barbieri Mestriner, Jakob Ackermann, Andreas H Gomoll
PURPOSE OF REVIEW: This review provides an overview of well-established and newly developed cartilage repair techniques for cartilage defects in the patellofemoral joint (PFJ). An algorithm will be presented for approaching cartilage defects considering the distinct anatomy of both the patellar and trochlear articular surfaces. RECENT FINDINGS: Recent studies on cartilage repair in the PFJ have demonstrated improved outcomes in an attempt to delay or obviate the need for arthroplasty, and improve symptoms in young patients...
May 18, 2018: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/29774751/evaluation-of-articular-cartilage-injury-using-computed-tomography-with-axial-traction-in-the-ankle-joint
#3
Tomoyuki Nakasa, Yasunari Ikuta, Mikiya Sawa, Masahiro Yoshikawa, Yusuke Tsuyuguchi, Yuki Ota, Munekazu Kanemitsu, Nobuo Adachi
BACKGROUND: Although chondral or osteochondral injuries are usually assessed by magnetic resonance imaging, its accuracy can be low, presumably related to the relatively thin cartilage layer and the close apposition of the cartilage of the talus and tibial plafond. We hypothesized that axial traction could provide a contrast between the articular cartilage and joint cavity, and it enabled the simultaneous evaluation of cartilage and subchondral bone. The purpose of this study was to assess the feasibility of using computed tomography (CT) imaging with axial traction for the diagnosis of articular cartilage injuries...
May 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29761933/th1-th17-th22-immune-response-and-their-association-with-joint-pain-imagenological-bone-loss-rankl-expression-and-osteoclast-activity-in-temporomandibular-joint-osteoarthritis-a-preliminary-report
#4
Gustavo Monasterio, Francisca Castillo, Leticia Rojas, Emilio A Cafferata, Carla Alvarez, Paola Carvajal, Cristián Núñez, Guillermo Flores, Walter Díaz, Rolando Vernal
It is well accepted that the presence of cytokines belonging to the Th1/Th17/Th22 axis of immuno-inflammatory response in the joint environment, such as IL-1β, IL-17, and IL-22, respectively, are associated with pathogenesis of several synovial joint degenerative disorders. During temporomandibular joint osteoarthritis (TMJ-OA), IL-1β and IL-17 have been implicated in the inflammation and resorption of sub-chondral bone; however, the role of Th22-response in the TMJ-OA pathophysiology has not been established...
May 15, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29758582/-relevance-of-mri-after-closed-reduction-of-traumatic-hip-dislocation-in-children
#5
Christoph Mauritz Strüwind, Christian von Rüden, Andreas Thannheimer, Volker Bühren, Dorien Schneidmueller
BACKGROUND: Traumatic hip dislocation in children and adolescents is a rare entity that typically results from high-energy trauma. After closed joint reduction, further treatment depends on the specific pattern of the lesion as identified using cross sectional imaging. The aim of this retrospective analysis was to evaluate relevant side effects after traumatic hip dislocation in children and adolescents in order to examine the need for focused diagnostics. PATIENTS/MATERIAL AND METHODS: This retrospective analysis covered 8 adolescents under 18 years suffering isolated traumatic hip joint dislocation between 2001 and 2017...
May 14, 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29756533/genetic-engineering-of-mesenchymal-stem-cells-for-differential-matrix-deposition-on-3dwoven-scaffold
#6
Nguyen Phuong Thao Huynh, Jonathan Matthew Brunger, Catherine Claire Gloss, Franklin T Moutos, Charles A Gersbach, Farshid Guilak
Tissue engineering approaches for the repair of osteochondral defects using biomaterial scaffolds and stem cells have remained challenging due to the inherent complexities of inducing cartilage-like matrix and bone-like matrix within the same local environment. Members of the transforming growth factor β (TGFβ) family have been extensively utilized in the engineering of skeletal tissues, but have distinct effects on chondrogenic and osteogenic differentiation of progenitor cells. The goal of this study was to develop a method to direct human bone marrow derived mesenchymal stem cells (MSCs) to deposit either mineralized matrix or a cartilaginous matrix rich in glycosaminoglycan and type II collagen within the same biochemical environment...
May 14, 2018: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29752207/a-cross-sport-comparison-of-performance-based-outcomes-of-professional-athletes-following-primary-microfracture-of-the-knee
#7
Michael S Schallmo, Sameer K Singh, Kathryn A Barth, Ryan D Freshman, Harry T Mai, Wellington K Hsu
BACKGROUND: The purpose of this study was to compare performance-based outcomes among professional athletes in four major North American sports following microfracture to treat symptomatic chondral defects of the knee. METHODS: Major League Baseball (MLB), National Basketball Association (NBA), National Football League (NFL), and National Hockey League (NHL) athletes who underwent primary unilateral microfracture of the knee were identified through a previously reported protocol based on public sources...
May 8, 2018: Knee
https://www.readbyqxmd.com/read/29750846/evaluation-of-the-diagnostic-accuracy-of-skeletal-scintigraphy-for-the-causes-of-front-foot-pain-determined-by-magnetic-resonance-imaging
#8
Laura E Quiney, Joanne L Ireland, Sue J Dyson
There is good correlation between increased radiopharmaceutical uptake anywhere in the feet of sports or leisure horses and the presence of foot pain. However, low sensitivity of scintigraphy for identifying lesions contributing to foot pain as determined by magnetic resonance imaging (MRI) has been reported. The aim of this retrospective, cross-sectional, analytical study was to assess the accuracy of scintigraphy for identifying the cause(s) of foot pain, using MRI as the reference standard. Sports and leisure horses that underwent both skeletal scintigraphy and MRI of the front feet between March 2008 and December 2014 and for which a definitive diagnosis of the cause(s) of front foot pain was reached were included (121 feet of 70 horses)...
May 11, 2018: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/29744431/analysis-of-the-in-vitro-degradation-and-the-in-vivo-tissue-response-to-bi-layered-3d-printed-scaffolds-combining-pla-and-biphasic-pla-bioglass-components-guidance-of-the-inflammatory-response-as-basis-for-osteochondral-regeneration
#9
Mike Barbeck, Tiziano Serra, Patrick Booms, Sanja Stojanovic, Stevo Najman, Elisabeth Engel, Robert Sader, Charles James Kirkpatrick, Melba Navarro, Shahram Ghanaati
The aim of the present study was the in vitro and in vivo analysis of a bi-layered 3D-printed scaffold combining a PLA layer and a biphasic PLA/bioglass G5 layer for regeneration of osteochondral defects in vivo Focus of the in vitro analysis was on the (molecular) weight loss and the morphological and mechanical variations after immersion in SBF. The in vivo study focused on analysis of the tissue reactions and differences in the implant bed vascularization using an established subcutaneous implantation model in CD-1 mice and established histological and histomorphometrical methods...
December 2017: Bioactive Materials
https://www.readbyqxmd.com/read/29739464/in-vivo-cartilage-tissue-engineering
#10
B Gurer, S Cabuk, O Karakus, N Yilmaz, C Yilmaz
BACKGROUND: Biologic treatment options for cartilage injuries require chondrocyte expansion using cell culture. Clinical application is accomplished in two surgical sessions and is expensive. If isolation of chondrocytes and stimulus for proliferation and extracellular matrix synthesis can be achieved in vivo, the treatment can be performed in one session and the cost can be reduced. METHODS: A 2.5-cm diameter full-thickness chondral defect was created in the knees of five groups of sheep...
May 8, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29736586/large-animal-models-for-osteochondral-regeneration
#11
Isabel R Dias, Carlos A Viegas, Pedro P Carvalho
Namely, in the last two decades, large animal models - small ruminants (sheep and goats), pigs, dogs and horses - have been used to study the physiopathology and to develop new therapeutic procedures to treat human clinical osteoarthritis. For that purpose, cartilage and/or osteochondral defects are generally performed in the stifle joint of selected large animal models at the condylar and trochlear femoral areas where spontaneous regeneration should be excluded. Experimental animal care and protection legislation and guideline documents of the US Food and Drug Administration, the American Society for Testing and Materials and the International Cartilage Repair Society should be followed, and also the specificities of the animal species used for these studies must be taken into account, such as the cartilage thickness of the selected defect localization, the defined cartilage critical size defect and the joint anatomy in view of the post-operative techniques to be performed to evaluate the chondral/osteochondral repair...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29731871/co-implantation-of-bone-marrow-mesenchymal-stem-cells-and-chondrocytes-increase-the-viability-of-chondrocytes-in-rat-osteo-chondral-defects
#12
Zhi Zhao, Xinshe Zhou, Jianzhong Guan, Min Wu, Jiansheng Zhou
Replacement of chondrocytes by adult stem cells was believed to improve the performance of autologous chondrocytes transplantation, since less chondrocytes were needed. Previous studies have demonstrated that the increased cartilage production in pellet co-cultures of chondrocytes and bone marrow mesenchymal stem cells (BMSCs) is due to the trophic effects of the MSC by stimulating chondrocyte proliferation and matrix production. However, the destination of MSCs or chondrocytes after implanted in osteo-chondral defects is not clear...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29731319/the-influence-of-tibial-slope-on-the-graft-in-combined-high-tibial-osteotomy-and-anterior-cruciate-ligament-reconstruction
#13
Philipp Schuster, Markus Geßlein, Michael Schlumberger, Philipp Mayer, Jörg Richter
BACKGROUND: Young patients with severe medial osteoarthritis, varus malalignment and insufficiency of the anterior cruciate ligament (ACL) are difficult to treat. The tibial slope has gained attention with regard to osteotomies and ligamentous instability. The purpose was to evaluate the outcome of combined high tibial osteotomy (HTO), ACL reconstruction and chondral resurfacing (CR, abrasion plus microfracture), and to analyse graft failure rates with regard to the tibial slope. METHODS: Fifty cases (48...
May 3, 2018: Knee
https://www.readbyqxmd.com/read/29730219/prevalence-of-high-grade-cartilage-defects-in-patients-with-borderline-dysplasia-with-femoroacetabular-impingement-a-comparative-cohort-study
#14
Ioanna K Bolia, Karen K Briggs, Renato Locks, Jorge Chahla, Hajime Utsunomiya, Marc J Philippon
PURPOSE: To compare the prevalence, size, and location of Outerbridge grade III and IV cartilage defects on the femoral head and acetabulum between patients with borderline acetabular dysplasia and patients with non-borderline dysplasia who underwent hip arthroscopy for femoroacetabular impingement (FAI). METHODS: Patients aged 18 years or older who underwent primary hip arthroscopy for correction of FAI and labral repair from November 2005 to April 2016 were included...
May 2, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29729758/editorial-commentary-cell-based-therapy-for-treatment-of-chondral-lesions-of-the-patellofemoral-joint-using-particulated-juvenile-chondrocytes
#15
EDITORIAL
Samuel K Tabet
The potential of cell-based therapies to fill articular cartilage defects is no longer a "pipe dream." Filling an articular cartilage defect with at least a "mixed hyaline cartilage" repair is no longer a question. The task at hand is somehow refining and defining the when, where, what, and how of the cartilage-growing procedures. The new ideas emerging are reflected in the recent literature, and all ideas regarding the specifics of these cartilage techniques and their outcomes should be welcomed...
May 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29728886/development-of-a-novel-large-animal-model-to-evaluate-human-dental-pulp-stem-cells-for-articular-cartilage-treatment
#16
Tiago Lazzaretti Fernandes, Kazunori Shimomura, Andre Asperti, Carla Cristina Gomes Pinheiro, Heloísa Vasconcellos Amaral Caetano, Claudia Regina G C M Oliveira, Norimasa Nakamura, Arnaldo José Hernandez, Daniela Franco Bueno
PURPOSE: Chondral lesion is a pathology with high prevalence, reaching as much as 63% of general population and 36% among athletes. The ability of human Dental Pulp Stem Cells (DPSCs) to differentiate into chondroblasts in vitro suggests that this stem cell type may be useful for tissue bioengineering. However, we have yet to identify a study of large animal models in which DPSCs were used to repair articular cartilage. Therefore, this study aimed to describe a novel treatment for cartilage lesion with DPSCs on a large animal model...
May 4, 2018: Stem Cell Reviews
https://www.readbyqxmd.com/read/29727866/gender-disparity-between-absolute-versus-relative-size-of-condylar-chondral-defects-an-mri-analysis
#17
Daniel Berman, Kelly Rogers, Kevin Bonner, Justin Griffin
Surgical repair of articular cartilage defects in the knee currently utilizes surgical algorithms based on absolute defect size. These algorithms, which have not been validated, are currently utilized not only by surgeons but also by insurance carriers for justification of reimbursement policy. However, current algorithms do not account for morphological differences between individual patients and defect size relative to condylar dimension. We hypothesized that a significant difference in relative defect size compared with condylar dimension may exist between individuals...
May 4, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29704190/tissue-engineering-in-osteoarthritis-current-status-and-prospect-of-mesenchymal-stem-cell-therapy
#18
Gun-Il Im
Osteoarthritis (OA) is the most common form of arthritis. Over the last 20 years, attempts have been made to regenerate articular cartilage to overcome the limitations of conventional treatments. As OA is generally associated with larger and diffuse involvement of articular surfaces and alteration of joint homeostasis, a tissue engineering approach for cartilage regeneration is more difficult than in simple chondral defects. Autologous and allogeneic mesenchymal stem cells (MSCs) have rapidly emerged as investigational products for cartilage regeneration...
April 27, 2018: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
https://www.readbyqxmd.com/read/29701088/outcome-of-autologous-bone-grafting-with-preservation-of-articular-cartilage-to-treat-osteochondral-lesions-of-the-talus-with-large-associated-subchondral-cysts
#19
M Sawa, T Nakasa, Y Ikuta, M Yoshikawa, Y Tsuyuguchi, M Kanemitsu, Y Ota, N Adachi
Aims The aim of this study was to evaluate antegrade autologous bone grafting with the preservation of articular cartilage in the treatment of symptomatic osteochondral lesions of the talus with subchondral cysts. Patients and Methods The study involved seven men and five women; their mean age was 35.9 years (14 to 70). All lesions included full-thickness articular cartilage extending through subchondral bone and were associated with subchondral cysts. Medial lesions were exposed through an oblique medial malleolar osteotomy, and one lateral lesion was exposed by expanding an anterolateral arthroscopic portal...
May 1, 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29699841/lateral-meniscus-allograft-transplantation-with-platelet-rich-plasma-injections-a-minimum-two-year-follow-up-study
#20
Hua Zhang, Shiyang Chen, Man Qiu, Aiguo Zhou, Wenlong Yan, Jian Zhang
BACKGROUND: The aim of this study was to report the short-term clinical and imaging outcomes of lateral meniscus allograft transplantations (LMAT) combined with intra-articular platelet-rich plasma (PRP) injection. METHODS: Thirty-three patients who had undergone LMAT combined with intra-articular PRP injection were evaluated. The Lysholm, International Knee Documentation Committee (IKDC), Western Ontario and McMaster Universities Osteoarthritis Index, Tegner activity level scale and visual analog scale for pain scores were used to evaluate the outcomes...
April 24, 2018: Knee
keyword
keyword
9894
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"