keyword
MENU ▼
Read by QxMD icon Read
search

Chondral

keyword
https://www.readbyqxmd.com/read/29164531/biphasic-bioresorbable-scaffold-trufit-%C3%A2-in-knee-osteochondral-defects-3-t-mri-evaluation-of-osteointegration-in-patients-with-a-5-year-minimum-follow-up
#1
G Bugelli, F Ascione, G Dell'Osso, V Zampa, S Giannotti
PURPOSE: The aim of this study is to follow morphological imaging characteristics and osteointegration of TruFit(®) bone graft substitute (BGS) plugs in cases of chondral and osteochondral defects of the articular surface of the knee joint, using high-quality cartilage-sensitive 3-T magnetic resonance imaging (MRI), linked to clinical outcomes. METHODS: The MRI was used to assess osteointegration and biological evolution of the TruFit(®) BGS plugs in cases with minimum 5-year follow-up: The TruFit(®) plug was used in 46 patients for a total of 47 cases with mean age of 57...
November 21, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/29163952/in-office-arthroscopy-for-the-evaluation-of-chronic-knee-pain-a-case-report
#2
Jacob A West, Nirav H Amin
This is a case report detailing the use of in-office needle arthroscopy (mi-eye 2™) in a patient with chronic knee pain and inconclusive magnetic resonance imaging findings. The patient is a 40-year-old male who presented to our clinic after an extended history of right knee pain along the medial aspect with previous failed treatments. Magnetic resonance imaging without contrast had demonstrated full-thickness chondral fissuring of the lateral patellar facet, mild abnormal signals of the proximal patellar tendon and Hoffa's fat pad, and intact anterior cruciate ligament and posterior cruciate ligament...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/29161138/autologous-matrix-induced-chondrogenesis-a-systematic-review-of-the-clinical-evidence
#3
Liang Gao, Patrick Orth, Magali Cucchiarini, Henning Madry
BACKGROUND: The addition of a type I/III collagen membrane in cartilage defects treated with microfracture has been advocated for cartilage repair, termed "autologous matrix-induced chondrogenesis" (AMIC). PURPOSE: To examine the current clinical evidence regarding AMIC for focal chondral defects. STUDY DESIGN: Systematic review. METHODS: A systematic review was performed by searching PubMed, ScienceDirect, and Cochrane Library databases...
November 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29157843/predictors-of-osteoarthritis-following-operative-treatment-of-medial-tibial-plateau-fractures
#4
Markus Parkkinen, Jan Lindahl, Tatu J Mäkinen, Seppo K Koskinen, Antti Mustonen, Rami Madanat
PURPOSE: To determine factors influencing the development of posttraumatic osteoarthritis (OA) following medial tibial plateau fractures and to evaluate concomitant injuries associated with these fractures. MATERIALS AND METHODS: A chart review of patients with operatively treated medial tibial plateau fractures admitted to our Level I trauma centre from 2002 to 2008 was performed. Of 63 patients, 41 participated in a clinical and radiographic examination. The mean age was 47 years (range 16-78) and the mean follow-up time was 7...
November 14, 2017: Injury
https://www.readbyqxmd.com/read/29156980/platelet-rich-plasma-and-hyaluronic-acid-are-not-synergistic-when-used-as-biological-adjuncts-with-autologous-osteochondral-transplantation
#5
Niall A Smyth, Keir A Ross, Amgad M Haleem, Charles P Hannon, Christopher D Murawski, Huong T Do, John G Kennedy
INTRODUCTION: Autologous osteochondral transplantation (AOT) is a treatment for osteochondral lesions with known concerns, including histological degradation of the graft and poor cartilage integration. Platelet-rich plasma (PRP) and hyaluronic acid (HA) have been described has having the potential to improve results. The aim of this study was to evaluate the effect of PRP and HA on AOT in a rabbit model. METHODS: Thirty-six rabbits underwent bilateral knee AOT treated with either the biological adjunct (PRP, n = 12; HA, n = 12; PRP + HA, n = 12) or saline (control)...
January 1, 2017: Cartilage
https://www.readbyqxmd.com/read/29146509/isolated-coronal-shear-fracture-of-the-nonossified-humeral-trochlea-in-a-7-year-old-patient
#6
Michiyo Tomaru, Denju Osada, Kazuya Tamai, Hiroshi Taneichi
Coronal shear fractures of the nonossified humeral trochlea are extremely rare in skeletally immature children. This fracture is difficult to diagnose accurately on routine radiographs. In addition, the mechanism of injury and appropriate treatment methods are unknown. We present the case of a 7-year-old boy who sustained an isolated coronal shear fracture of the nonossified humeral trochlea. Internal fixation of the fracture was performed with 2 K-wires. Two and a half years after surgery, the patient had pain-free active range of motion of the elbow from 0° to 130° with full forearm rotation and magnetic resonance imaging showed healing of the chondral fragment of the trochlea...
November 14, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29146169/arthroscopy-after-traumatic-hip-dislocation-a%C3%A2-systematic-review-of-intra-articular-findings-correlation-with-magnetic-resonance-imaging-and-computed-tomography-treatments-and-outcomes
#7
REVIEW
Jacob C Mandell, Richard A Marshall, Michael B Banffy, Bharti Khurana, Michael J Weaver
PURPOSE: To describe the literature concerning patient demographic characteristics and intra-articular injury seen at arthroscopy after traumatic hip dislocation, describe the reported computed tomography (CT) and magnetic resonance findings with arthroscopic correlation, and describe the reported arthroscopic treatments performed with complications and outcomes. METHODS: A systematic review was performed following Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines for assessment of arthroscopy after hip dislocation...
November 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29145965/increased-cytokine-levels-and-histological-changes-in-cartilage-synovial-cells-and-synovial-fluid-after-malleolar-fractures
#8
Alexandre L Godoy-Santos, Lucas Ranzoni, Walcy R Teodoro, Vera Capelozzi, Pedro Giglio, Tulio Diniz Fernandes, Stefan Rammelt
BACKGROUND: Malleolar fractures are among the most common fractures in the human skeleton with a high risk of later development of post-traumatic osteoarthritis (OA). The acute ankle injury initiates a sequence of events potentially leading to progressive articular surface damage resulting from inflammatory changes in cartilage, synovial tissue and synovial fluid. We hypothesised that in the acute phase of ankle fracture, these changes occur at the same time in the different tissues. METHODS: Specimens of chondral tissue, synovial tissue and synovial fluid were collected from 16 patients with acute articular ankle fracture (study group)...
October 2017: Injury
https://www.readbyqxmd.com/read/29138892/-partial-and-complete-joint-transplantation-with-fresh-osteochondral-allografts-the-flocsat-concept
#9
REVIEW
C Krettek, J-D Clausen, N Bruns, C Neunaber
Cartilage defects in adult patients do not heal well. Fresh osteochondral allograft (OCA) transplantation is based on mature, living, mechanically sound hyaline cartilage attached to a bone interface, which is brought into an osteochondral defect, where it becomes osseointegrated. According to current knowledge, intact hyaline cartilage tissue is immune privileged and does not, in contrast to bone, meniscus or ligaments, cause an immune reaction. The technique has the unique advantage of transplanting viable, mature and mechanically stable hyaline cartilage into the affected area...
November 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/29135288/selective-debridement-with-labral-preservation-using-narrow-indications-in-the-hip-minimum-5-year-outcomes-with-a-matched-pair-labral-repair-control-group
#10
Austin W Chen, Leslie C Yuen, Victor Ortiz-Declet, Jody Litrenta, David R Maldonado, Benjamin G Domb
BACKGROUND: Arthroscopic labral debridement in the hip can be an effective treatment for labral tears but has demonstrated inferior outcomes compared with labral repair. Thus, the role for labral debridement has become unclear. Hypothesis/Purpose: The purpose was to evaluate the outcomes of a selective debridement with labral preservation (SDLP) group with a minimum 5-year follow-up. It was hypothesized that, with narrow indications, SDLP would produce statistically improved patient-reported outcome (PRO) scores, comparable with those of a matched-pair labral repair control group...
November 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29135269/return-to-play-after-hip-arthroscopic-surgery-for-femoroacetabular-impingement-in-professional-soccer-players
#11
Renato Locks, Hajime Utsunomiya, Karen K Briggs, Shannen McNamara, Jorge Chahla, Marc J Philippon
BACKGROUND: Arthroscopic hip surgery has been shown to be effective in returning professional athletes back to play at a high level of performance in different sports. Limited information exists regarding professional soccer players and their return to play. PURPOSE: To determine the rate and time to return to sport for professional soccer players after hip arthroscopic surgery for the treatment of femoroacetabular impingement (FAI) and to identify possible risk factors associated with a delay in returning to play...
November 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29132328/posterior-shoulder-dislocation-with-associated-reverse-hill-sachs-lesion-treatment-options-and-functional-outcome-after-a-5-year-follow-up
#12
Markus Guehring, Simon Lambert, Ulrich Stoeckle, Patrick Ziegler
BACKGROUND: The current study describes several surgical techniques for the treatment of the reverse Hill - Sachs lesion after posterior shoulder dislocation; we also aimed to present long term results followed for a minimum of five years. METHODS: This study is a prospective case series of 17 patients who were treated in our clinic between 2008 and 2011. Patients with a defect size smaller than 25% of the articular surface were treated conservatively. An endoprosthesis of the glenohumeral joint was implanted in patients with a defect size bigger than 40%...
November 13, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29128537/biomaterials-for-articular-cartilage-tissue-engineering-learning-from-biology
#13
REVIEW
A R Armiento, M J Stoddart, M Alini, D Eglin
Articular cartilage is commonly described as a tissue made of up to 80% water, devoid of blood vessels, nerves and lymphatics, and populated by only one cell type: at first glance, an easy tissue for clinicians to repair and for scientists to reproduce in a laboratory. Yet, chondral and osteochondral defects currently remain an open challenge in orthopedics and tissue engineering of the musculoskeletal system, without considering osteoarthritis. Why do we fail in repairing and regenerating articular cartilage? Behind its simple and homogenous appearance articular cartilage hides a heterogeneous composition, a high level of organisation and specific biomechanical properties that taken together make articular cartilage a unique material that we are not able yet to repair or reproduce with high fidelity...
November 8, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29126408/concomitant-glenohumeral-pathologies-in-high-grade-acromioclavicular-separation-type-iii-v
#14
Jochen Markel, Tim Schwarting, Dominik Malcherczyk, Christian-Dominik Peterlein, Steffen Ruchholtz, Bilal Farouk El-Zayat
BACKGROUND: Acromioclavicular joint (ACJ) dislocations are common injuries of the shoulder associated with physical activity. The diagnosis of concomitant injuries proves complicated due to the prominent clinical symptoms of acute ACJ dislocation. Because of increasing use of minimally invasive surgery techniques concomitant pathologies are diagnosed more often than with previous procedures. METHODS: The aim of this study was to identify the incidence of concomitant intraarticular injuries in patients with high-grade acromioclavicular separation (Rockwood type III - V) as well as to reveal potential risk constellations...
November 10, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29126349/bone-marrow-aspirate-concentrate-for-cartilage-defects-of-the-knee-from-bench-to-bedside-evidence
#15
Eric J Cotter, Kevin C Wang, Adam B Yanke, Susan Chubinskaya
Objective To critically evaluate the current basic science, translational, and clinical data regarding bone marrow aspirate concentrate (BMAC) in the setting of focal cartilage defects of the knee and describe clinical indications and future research questions surrounding the clinical utility of BMAC for treatment of these lesions. Design A literature search was performed using the PubMed and Ovid MEDLINE databases for studies in English (1980-2017) using keywords, including ["bone marrow aspirate" and "cartilage"], ["mesenchymal stem cells" and "cartilage"], and ["bone marrow aspirate" and "mesenchymal stem cells" and "orthopedics"]...
November 1, 2017: Cartilage
https://www.readbyqxmd.com/read/29115031/biomimetic-multidirectional-scaffolds-for-zonal-osteochondral-tissue-engineering-via-a-lyophilization-bonding-approach-1
#16
Drew Clearfield, Andrew Nguyen, Mei Wei
The zonal organization of osteochondral tissue underlies its long term function. Despite this, tissue engineering strategies targeted for osteochondral repair commonly rely on the use of isotropic biomaterials for tissue reconstruction. There exists a need for a new class of highly biomimetic, anisotropic scaffolds that may allow for the engineering of new tissue with zonal properties. To address this need, we report the facile production of monolithic multidirectional collagen-based scaffolds that recapitulate the zonal structure and composition of osteochondral tissue...
November 7, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29114627/second-generation-needling-techniques-for-the-treatment-of-chondral-defects-in-animal-model
#17
Pietro Zedde, Sebastiano Cudoni, Lucia Manunta, Eraldo Sanna Passino, Gerolamo Masala, Antonio Brunetti, Francesco Mattia Uboldi, Andrea Fabio Manunta
Purpose  To compare the macroscopic, histological, and immunohistochemical characteristics of the repair tissue of chondral defects treated with microfracture and nanofracture in an ovine model. Methods  Full-thickness chondral lesions were created in the medial femoral condyle of both knees in four adult sheep and were treated with microfracture on one side and with nanofracture on the contralateral side. Chondral repair was assessed after 12 months by macroscopic, histological, and immunohistochemical analyses...
March 2017: Joints
https://www.readbyqxmd.com/read/29112467/meniscectomy-and-resultant-articular-cartilage-lesions-of-the-knee-among-prospective-national-football-league-players-an-imaging-and-performance-analysis
#18
Jorge Chahla, Mark E Cinque, Jonathan A Godin, George Sanchez, George F Lebus, James M Whalen, Mark D Price, Nicholas I Kennedy, Gilbert Moatshe, Robert F LaPrade, Matthew T Provencher
BACKGROUND: The effect of prior meniscectomy and the resulting reduction in meniscal tissue on a potential National Football League (NFL) player's articular cartilage status and performance remain poorly elucidated. Purpose/Hypothesis: (1) To determine the epidemiology, imaging characteristics, and associated articular cartilage pathology of the knee among players with a previous meniscectomy who were participating in the NFL Combine and (2) to evaluate the effect of these injuries on performance as compared with matched controls...
November 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29109026/a-low-friction-biphasic-and-boundary-lubricating-hydrogel-for-cartilage-replacement
#19
Piers E Milner, Maria Parkes, Jennifer L Puetzer, Robert Chapman, Molly M Stevens, Philippa Cann, Jonathan Jeffers
Partial joint repair is a surgical procedure where an artificial material is used to replace localised chondral damage. These artificial bearing surfaces must articulate against cartilage, but current materials do not replicate both the biphasic and boundary lubrication mechanisms of cartilage. A research challenge therefore exists to provide a material that mimics both boundary and biphasic lubrication mechanisms of cartilage. In this work a polymeric network of a biomimetic boundary lubricant, poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC), was incorporated into an ultra-tough double network (DN) biphasic (water phase + polymer phase) gel, to form a PMPC triple network (PMPC TN) hydrogel with boundary and biphasic lubrication capability...
November 3, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29106758/transcriptomic-analysis-of-synovial-extracellular-rna-following-knee-trauma-a-pilot-study
#20
Anthony J Griswold, Jose Perez, Karen Nuytemans, Thomas Strong, Liyong Wang, Danica D Vance, Hayley Ennis, Marvin K Smith, Thomas M Best, Jeffery M Vance, Margaret A Pericak-Vance, Lee D Kaplan
Traumatic knee injuries often result in damage to articular cartilage and other joint structures. Such trauma is a strong risk factor for the future development and progression of osteoarthritis (OA). The molecular mechanisms and signaling pathways modulating response to knee joint trauma remain unclear. Moreover, investigations of biomarkers influencing responses have been targeted rather than broad, unbiased discovery studies. Herein we characterize the complete complement of extracellular RNA (exRNA) in the synovial fluid of 14 subjects following knee injury...
November 6, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
keyword
keyword
9894
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"