keyword
https://read.qxmd.com/read/38537045/digital-analysis-of-unilateral-ptosis-repair-external-levator-advancement-vs-m%C3%A3-ller-s-muscle-conjunctival-resection
#1
JOURNAL ARTICLE
Serdar Bilici, Tomurcuk Harbigil-Sever, Suat Hayri Ugurbas
PURPOSE: Evaluation of lid contour and marginal peak point changes to compare outcomes of external levator advancement and Miiller's muscle conjunctival resection surgery in unilateral ptosis. METHODS: We reviewed the charts of unilateral ptosis patients who underwent external levator advancement or Miiller's muscle conjunctival resection. Eyelid contour analysis was conducted on preoperative and 6-month postoperative digital images. This was performed with the multiple margin reflex distances technique, measuring the vertical distance from a line intersecting the center of the pupil to the eyelid margin at 10 positions at 2 mm intervals...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38536965/nonadiabatic-conical-intersection-dynamics-in-the-local-diabatic-representation-with-strang-splitting-and-fourier-basis
#2
JOURNAL ARTICLE
Bing Gu
We develop and implement an exact conical intersection nonadiabatic wave packet dynamics method that combines the local diabatic representation, Strang splitting for the total molecular propagator, and discrete variable representation with uniform grids. By employing the local diabatic representation, this method captures all nonadiabatic effects, including nonadiabatic transitions, electronic coherences, and geometric phase. Moreover, it is free of singularities in the first and second derivative couplings and does not require the electronic wave function to be continuous with respect to the nuclear coordinates...
March 27, 2024: Journal of Chemical Theory and Computation
https://read.qxmd.com/read/38536963/affinity-tagged-smad1-and-smad5-mouse-lines-reveal-transcriptional-reprogramming-mechanisms-during-early-pregnancy
#3
JOURNAL ARTICLE
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin Matzuk
Endometrial decidualization, a prerequisite for successful pregnancies, relies on transcriptional reprogramming driven by progesterone receptor (PR) and bone morphogenetic protein (BMP)-SMAD1/SMAD5 signaling pathways. Despite their critical roles in early pregnancy, how these pathways intersect in reprogramming the endometrium into a receptive state remains unclear. To define how SMAD1 and/or SMAD5 integrate BMP signaling in the uterus during early pregnancy, we generated two novel transgenic mouse lines with affinity tags inserted into the endogenous SMAD1 and SMAD5 loci ( Smad1HA/HA and Smad5PA/PA )...
March 27, 2024: ELife
https://read.qxmd.com/read/38536114/how-does-our-brain-process-positive-and-negative-thermosensory-cues
#4
REVIEW
Jose Gabriel Grajales-Reyes, Bandy Chen, David Meseguer Garcia, Marc Schneeberger Pane
Whether it is the dramatic suffocating sensation from a heat wave in the summer or the positive reinforcement arising from a hot drink on a cold day; we can certainly agree that our thermal environment underlies our daily rhythms of sensation. Extensive research has focused on deciphering the central circuits responsible for conveying the impact of thermogenesis on mammalian behavior. Here, we revise the recent literature responsible for defining the behavioral correlates that arise from thermogenic fluctuations in mammals...
March 27, 2024: Physiology
https://read.qxmd.com/read/38536052/spirituality-and-people-with-psychosis-a-content-analysis-of-influential-primetime-television-programs
#5
JOURNAL ARTICLE
David R Hodge, Patricia R Turner
OBJECTIVE: This mixed methods study examined depictions of spirituality among people with psychosis in influential television programming. Spirituality is a central strength for many people with psychosis. Yet, despite the important role media plays in shaping perceptions, little research has examined the intersection between spirituality and psychosis in popular media. METHODS: To address this gap, we conducted a content analysis of the 50 most viewed primetime fictional television shows over a 10-year period as determined by the Nielsen rating organization...
March 27, 2024: International Journal of Psychiatry in Medicine
https://read.qxmd.com/read/38535652/-polymerization-of-bimerons-in-quasi-two-dimensional-chiral-magnets-with-easy-plane-anisotropy
#6
JOURNAL ARTICLE
Natsuki Mukai, Andrey O Leonov
We re-examine the internal structure of bimerons, which are stabilized in easy-plane chiral magnets and represent coupled states of two merons with the same topological charge |1/2| but with opposite vorticity and the polarity. We find that, in addition to the vortices and antivortices, bimerons feature circular regions which are located behind the anti-vortices and bear the rotational sense opposite to the rotational sense chosen by the Dzyaloshinskii-Moriya interaction. In an attempt to eliminate these wrong-twist regions with an excess of positive energy density, bimerons assemble into chains, and as such exhibit an attracting interaction potential...
March 11, 2024: Nanomaterials
https://read.qxmd.com/read/38535552/human-papillomavirus-hpv-infection-and-risk-behavior-in-vaccinated-and-non-vaccinated-paraguayan-young-women
#7
JOURNAL ARTICLE
María Liz Bobadilla, Verónica Villagra, Héctor Castro, Marta von Horoch, Soraya Araya, Gerardo Deluca, Vanessa Salete de Paula
Cervical cancer is a global health concern and ranks fourth among the most prevalent cancers in women worldwide. Human papillomavirus (HPV) infection is a known precursor of cervical cancer and preventive measures include prophylactic vaccines. This study focused on sexually active Paraguayan women aged 18-25 years, exploring the intersection of HPV vaccination and sexual behavior. Among 254 participants, 40.9% received the Gardasil-4 vaccine, with no significant differences in sexual behavior between the vaccinated and unvaccinated sexually active groups...
February 27, 2024: Pathogens
https://read.qxmd.com/read/38535525/drought-stress-influences-foraging-preference-of-a-solitary-bee-on-two-wildflowers
#8
JOURNAL ARTICLE
Annika Rose-Person, Louis S Santiago, Nicole E Rafferty
BACKGROUND AND AIMS: Pollinators provide critical ecosystem services, maintaining biodiversity and benefiting global food production. However, plants, pollinators, and their mutualistic interactions may be affected by drought, which has increased in severity and frequency under climate change. Using two annual, insect-pollinated wildflowers (Phacelia campanularia and Nemophila menziesii), we asked how drought impacts floral traits and foraging preferences of a solitary bee (Osmia lignaria) and explore potential implications for plant reproduction...
March 27, 2024: Annals of Botany
https://read.qxmd.com/read/38535147/revolutionizing-cow-welfare-monitoring-a-novel-top-view-perspective-with-depth-camera-based-lameness-classification
#9
JOURNAL ARTICLE
San Chain Tun, Tsubasa Onizuka, Pyke Tin, Masaru Aikawa, Ikuo Kobayashi, Thi Thi Zin
This study innovates livestock health management, utilizing a top-view depth camera for accurate cow lameness detection, classification, and precise segmentation through integration with a 3D depth camera and deep learning, distinguishing it from 2D systems. It underscores the importance of early lameness detection in cattle and focuses on extracting depth data from the cow's body, with a specific emphasis on the back region's maximum value. Precise cow detection and tracking are achieved through the Detectron2 framework and Intersection Over Union (IOU) techniques...
March 8, 2024: Journal of Imaging
https://read.qxmd.com/read/38534928/adapting-an-adolescent-and-young-adult-program-housed-in-a-quaternary-cancer-centre-to-a-regional-cancer-centre-creating-equitable-access-to-developmentally-tailored-support
#10
JOURNAL ARTICLE
Marlie Smith, Simone Kurup, Kaviya Devaraja, Shaayini Shanawaz, Lorrie Reynolds, Jill Ross, Andrea Bezjak, Abha A Gupta, Alisha Kassam
Adolescents and young adults (AYAs) with cancer, representing those between 15 and 39 years of age, face distinctive challenges balancing their life stage with the physical, emotional, and social impacts of a cancer diagnosis. These challenges include fertility concerns, disruptions to educational and occupational pursuits, issues related to body image and sexual health, and the need for age-appropriate psychosocial support within their communities. The Princess Margaret Cancer Centre (PM), a quaternary care center, established a specialized AYA program in 2014, offering holistic and developmentally tailored psychosocial support and currently, efforts are underway to expand this to other regions in the province to address the need for equitable access...
February 27, 2024: Current Oncology
https://read.qxmd.com/read/38534802/temporal-considerations-in-brain-metastases-radiation-therapy-the-intersection-of-chronobiology-and-patient-profiles
#11
JOURNAL ARTICLE
Nicolas G Nelson, Sara E Burke, Louis Cappelli, Lauren E Matlack, Alexandria P Smith, Noelle Francois, Joseph F Lombardo, Yash B Shah, Kuang-Yi Wen, Ayesha A Shafi, Nicole L Simone
The circadian system, a vital temporal regulator influencing physiological processes, has implications for cancer development and treatment response. Our study assessed circadian timing's impact on whole-brain radiotherapy outcomes in brain metastases for personalized cancer therapy insights. The aim of the study was to evaluate circadian influence on radiation treatment timing and its correlation with clinical outcomes and to identify patient populations benefiting from interventions synchronizing circadian rhythms, considering subgroup differences and potential disparities...
March 21, 2024: Clocks & Sleep
https://read.qxmd.com/read/38534565/application-of-diy-electrodermal-activity-wristband-in-detecting-stress-and-affective-responses-of-students
#12
JOURNAL ARTICLE
Kenneth Y T Lim, Minh Tuan Nguyen Thien, Minh Anh Nguyen Duc, Hugo F Posada-Quintero
This paper describes the analysis of electrodermal activity (EDA) in the context of students' scholastic activity. Taking a multidisciplinary, citizen science and maker-centric approach, low-cost, bespoken wearables, such as a mini weather station and biometric wristband, were built. To investigate both physical health as well as stress, the instruments were first validated against research grade devices. Following this, a research experiment was created and conducted in the context of students' scholastic activity...
March 20, 2024: Bioengineering
https://read.qxmd.com/read/38534491/reimagining-radiology-a-comprehensive-overview-of-reviews-at-the-intersection-of-mobile-and-domiciliary-radiology-over-the-last-five-years
#13
REVIEW
Graziano Lepri, Francesco Oddi, Rosario Alfio Gulino, Daniele Giansanti
(Background) Domiciliary radiology, which originated in pioneering studies in 1958, has transformed healthcare, particularly during the COVID-19 pandemic, through advancements such as miniaturization and digitization. This evolution, driven by the synergy of advanced technologies and robust data networks, reshapes the intersection of domiciliary radiology and mobile technology in healthcare delivery. (Objective) The objective of this study is to overview the reviews in this field with reference to the last five years to face the state of development and integration of this practice in the health domain...
February 24, 2024: Bioengineering
https://read.qxmd.com/read/38534378/deep-learning-powered-identification-of-differentiated-early-mesoderm-cells-from-pluripotent-stem-cells
#14
JOURNAL ARTICLE
Sakib Mohammad, Arpan Roy, Andreas Karatzas, Sydney L Sarver, Iraklis Anagnostopoulos, Farhan Chowdhury
Pluripotent stem cells can be differentiated into all three germ-layers including ecto-, endo-, and mesoderm in vitro. However, the early identification and rapid characterization of each germ-layer in response to chemical and physical induction of differentiation is limited. This is a long-standing issue for rapid and high-throughput screening to determine lineage specification efficiency. Here, we present deep learning (DL) methodologies for predicting and classifying early mesoderm cells differentiated from embryoid bodies (EBs) based on cellular and nuclear morphologies...
March 18, 2024: Cells
https://read.qxmd.com/read/38534142/glycine-betaine-metabolism-is-enabled-in-methylorubrum-extorquens-pa1-by-alterations-to-dimethylglycine-dehydrogenase
#15
JOURNAL ARTICLE
Zachary T Hying, Tyler J Miller, Chin Yi Loh, Jannell V Bazurto
Low nutrient availability is a key characteristic of the phyllosphere (the aerial surface of plants). Phyllospheric bacteria utilize a wide array of carbon sources generated by plant hosts. Glycine betaine (GB) is a plant-derived compound that can be metabolized by certain members of the phyllosphere microbiota. Metabolism of glycine betaine generates formaldehyde, an intermediate of methylotrophic metabolism, leading us to investigate how the ubiquitous plant colonizing bacterium Methylorubrum extorquens PA1 might metabolize GB encountered in its native environment...
March 27, 2024: Applied and Environmental Microbiology
https://read.qxmd.com/read/38533079/-scutellaria-baicalensis-georgi-stems-and-leaves-flavonoids-promote-neuroregeneration-and-ameliorate-memory-loss-in-rats-through-camp-pka-creb-signaling-pathway-based-on-network-pharmacology-and-bioinformatics-analysis
#16
JOURNAL ARTICLE
Yinhui Yao, Qianqian Liu, Shengkai Ding, Yan Chen, Tangtang Song, Yazhen Shang
The aim of this study was to investigate the possible molecular mechanism of Scutellaria baicalensis Georgi stems and leaves flavonoids (SSF) in Alzheimer's disease (AD). The active ingredients of SSF and their targets were identified via network pharmacology and bioinformatics analysis. To test the successful establishment of a rat model of AD by Aβ25-35 combined with RHTGF- β 1 and AlCl3 , the Morris water maze test was used. To intervene, three different doses of SSF were administered. The model group and the control group were included among the parallel groups...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38532966/critical-perspective-on-infodemic-and-infodemic-management-in-previous-ebola-outbreaks-in-uganda
#17
JOURNAL ARTICLE
Sunday Jimmy Obol, Okechi Nzedibe
This research investigates the complex dynamics of Uganda's recent Ebola outbreaks, emphasizing the interplay between disease spread, misinformation, and existing societal vulnerabilities. Highlighting poverty as a core element, it delves into how socioeconomic factors exacerbate health crises. The study scrutinizes the role of political economy, medical pluralism, health systems, and informal networks in spreading misinformation, further complicating response efforts. Through a comprehensive analysis, this study aims to shed light on the multifaceted challenges faced in combating epidemics in resource-limited settings...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38532965/promoting-community-health-and-climate-justice-co-benefits-insights-from-a-rural-and-remote-island-climate-planning-process
#18
JOURNAL ARTICLE
Angel M Kennedy, Kiera Tsakonas, Forrest Berman-Hatch, Sophia Conradi, Max Thaysen, Manda Aufochs Gillespie, Maya K Gislason
Climate change is an environmental crisis, a health crisis, a socio-political and an economic crisis that illuminates the ways in which our human-environment relationships are arriving at crucial tipping points. Through these relational axes, social structures, and institutional practices, patterns of inequity are produced, wherein climate change disproportionately impacts several priority populations, including rural and remote communities. To make evidence-based change, it is important that engagements with climate change are informed by data that convey the nuance of various living realities and forms of knowledge; decisions are rooted in the social, structural, and ecological determinants of health; and an intersectional lens informs the research to action cycle...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38532933/novel-biomarkers-of-inflammation-associated-immunity-in-cervical-cancer
#19
JOURNAL ARTICLE
Weihong Zhao, Qi Li, Songquan Wen, Yaqin Li, Ying Bai, Zhiyu Tian
BACKGROUND: Cervical cancer (CC) is a highly malignant gynecological cancer with a direct causal link to inflammation, primarily resulting from persistent high-risk human papillomavirus (HPV) infection. Given the challenges in early detection and mid to late-stage treatment, our research aims to identify inflammation-associated immune biomarkers in CC. METHODS: Using a bioinformatics approach combined with experimental validation, we integrated two CC datasets (GSE39001 and GSE63514) in the Gene Expression Omnibus (GEO) to eliminate batch effects...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38532341/exploring-the-effect-of-xiao-chai-hu-decoction-on-treating-psoriasis-based-on-network-pharmacology-and-experiment-validation
#20
JOURNAL ARTICLE
Ke He, Ziyang Wang, Meng Liu, Wenqian Du, Tingyi Yin, Ruimin Bai, Qiqi Duan, Yuqian Wang, Hao Lei, Yan Zheng
BACKGROUND: Psoriasis is a chronic, inflammatory and recurrent skin disease. Xiao-Chai-Hu Decoction (XCHD) has shown good effects against some inflammatory diseases and cancers. However, the pharmacological effect and mechanisms of XCHD on psoriasis are not yet clear. OBJECTIVE: To uncover the effect and mechanisms of XCHD on psoriasis by integrating network pharmacology, molecular docking, and in vivo experiments. METHODS: The active ingredients and corresponding targets of XCHD were screened through Traditional Chinese Medicine Systems Pharmacology Database and Analysis (TCMSP) and Traditional Chinese Medicine Integrated Database (TCMID)...
2024: Current Pharmaceutical Design
keyword
keyword
98918
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.