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Transcranial electric stimulation

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https://www.readbyqxmd.com/read/29141551/noninvasive-cerebellar-stimulation-as-a-complement-tool-to-pharmacotherapy
#1
Roberta Ferrucci, Tommaso Bocci, Francesca Cortese, Fabiana Ruggiero, Alberto Priori
Cerebellar ataxias represent a wide and heterogeneous group of diseases characterized by balance and coordination disturbance, dysarthria, dyssynergia and adyadococinesia, caused by a dysfunction in the cerebellum. In recent years there has been growing interest in discovering therapeutical strategy for specific forms of cerebellar ataxia. Together with pharmacological studies, there has been growing interest in non-invasive cerebellar stimulation techniques to improve ataxia and limb coordination. Both transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) are non-invasive techniques to modulate cerebro and cerebellar cortex excitability using magnetic or electric fields...
November 14, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/29137989/does-tms-on-v3-block-conscious-visual-perception
#2
Niina Salminen-Vaparanta, Mika Koivisto, Victor Vorobyev, Kati Alakurtti, Antti Revonsuo
Primary visual cortex (V1) and extrastriate V2 are necessary for the emergence of visual consciousness, but the effects of involvement of extrastriate V3 on visual consciousness is unclear. The objective of this study was to examine the causal role of V3 in visual consciousness in humans. We combined neuronavigated transcranial magnetic stimulation (TMS) with a computational model of the TMS-induced electric field to test whether or not the intact processing of visual input in V3, like in V1 and V2, is necessary for conscious visual perception...
November 11, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29135963/comprehensive-survey-on-improved-focality-and-penetration-depth-of-transcranial-magnetic-stimulation-employing-multi-coil-arrays
#3
Xile Wei, Yao Li, Meili Lu, Jiang Wang, Guosheng Yi
Multi-coil arrays applied in transcranial magnetic stimulation (TMS) are proposed to accurately stimulate brain tissues and modulate neural activities by an induced electric field (EF). Composed of numerous independently driven coils, a multi-coil array has alternative energizing strategies to evoke EFs targeting at different cerebral regions. To improve the locating resolution and the stimulating focality, we need to fully understand the variation properties of induced EFs and the quantitative control method of the spatial arrangement of activating coils, both of which unfortunately are still unclear...
November 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29128578/electrical-brain-stimulation-tes-improves-learning-more-than-performance-a-meta-analysis
#4
REVIEW
Bianca A Simonsmeier, Roland H Grabner, Julia Hein, Ugne Krenz, Michael Schneider
Researchers have recently started evaluating whether stimulating the brain noninvasively with a weak and painless electrical current (transcranial Electrical Stimulation, tES) enhances physiological and cognitive processes. Some studies found that tES has weak but positive effects on brain physiology, cognition, or assessment performance, which have attracted massive public interest. We present the first meta-analytic test of the hypothesis that tES in a learning phase is more effective than tES in an assessment phase...
November 8, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29122535/limited-output-transcranial-electrical-stimulation-lotes-2017-engineering-principles-regulatory-statutes-and-industry-standards-for-wellness-over-the-counter-or-prescription-devices-with-low-risk
#5
Marom Bikson, Bhaskar Paneri, Andoni Mourdoukoutas, Zeinab Esmaeilpour, Bashar W Badran, Robin Azzam, Devin Adair, Abhishek Datta, Xiao Hui Fang, Brett Wingeier, Daniel Chao, Miguel Alonso-Alonso, Kiwon Lee, Helena Knotkova, Adam J Woods, David Hagedorn, Doug Jeffery, James Giordano, William J Tyler
We present device standards for low-power non-invasive electrical brain stimulation devices classified as limited output transcranial electrical stimulation (tES). Emerging applications of limited output tES to modulate brain function span techniques to stimulate brain or nerve structures, including transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), and transcranial pulsed current stimulation (tPCS), have engendered discussion on how access to technology should be regulated...
October 17, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29118716/etiology-and-recovery-of-neuromuscular-fatigue-following-competitive-soccer-match-play
#6
Callum G Brownstein, Jack P Dent, Paul Parker, Kirsty M Hicks, Glyn Howatson, Stuart Goodall, Kevin Thomas
Aim: Previous research into the etiology of neuromuscular fatigue following competitive soccer match-play has primarily focused on peripheral perturbations, with limited research assessing central nervous system function in the days post-match. The aim of the present study was to examine the contribution and time-course of recovery of central and peripheral factors toward neuromuscular fatigue following competitive soccer match-play. Methods: Sixteen male semi-professional soccer players completed a 90-min soccer match...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29118698/an-acute-exposure-to-muscle-vibration-decreases-knee-extensors-force-production-and-modulates-associated-central-nervous-system-excitability
#7
Robin Souron, Thibault Besson, Chris J McNeil, Thomas Lapole, Guillaume Y Millet
Local vibration (LV) has been recently validated as an efficient training method to improve muscle strength. Understanding the acute effects may help elucidate the mechanism(s). This study aimed to investigate the effects of a single bout of prolonged LV on knee extensor force production and corticospinal responsiveness of vastus lateralis (VL) and rectus femoris (RF) muscles in healthy young and old adults. Across two visits, 23 adult subjects (20-75 years old) performed pre- and post-test measurements, separated by 30-min of either rest (control; CON) or LV...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29118196/the-involvement-of-n-methyl-d-aspartate-receptors-in-plasticity-induced-by-paired-corticospinal-motoneuronal-stimulation-in-humans
#8
Siobhan C Donges, Jessica M D'Amico, Jane E Butler, Janet L Taylor
Plasticity can be induced at human corticospinal-motoneuronal synapses by delivering repeated, paired stimuli to corticospinal axons and motoneurones in a technique called paired corticospinal-motoneuronal stimulation (PCMS). To date, the mechanisms of the induced plasticity are unknown. To determine whether PCMS-induced plasticity is dependent on N-methyl-D-aspartate receptors (NMDARs), the effect of the non-competitive NMDAR antagonist, dextromethorphan, on PCMS-induced facilitation was assessed in a two-day, double-blind, placebo-controlled experiment...
November 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29115915/neuromodulation-in-multiple-sclerosis
#9
Hesham Abboud, Eddie Hill, Junaid Siddiqui, Alessandro Serra, Benjamin Walter
Neuromodulation, or the utilization of advanced technology for targeted electrical or chemical neuronal stimulation or inhibition, has been expanding in several neurological subspecialties. In the past decades, immune-modulating therapy has been the main focus of multiple sclerosis (MS) research with little attention to neuromodulation. However, with the recent advances in disease-modifying therapies, it is time to shift the focus of MS research to neuromodulation and restoration of function as with other neurological subspecialties...
November 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29093455/using-non-invasive-transcranial-stimulation-to-improve-motor-and-cognitive-function-in-parkinson-s-disease-a-systematic-review-and-meta-analysis
#10
Alicia M Goodwill, Jarrad A G Lum, Ashlee M Hendy, Makii Muthalib, Liam Johnson, Natalia Albein-Urios, Wei-Peng Teo
Parkinson's disease (PD) is a neurodegenerative disorder affecting motor and cognitive abilities. There is no cure for PD, therefore identifying safe therapies to alleviate symptoms remains a priority. This meta-analysis quantified the effectiveness of repetitive transcranial magnetic stimulation (rTMS) and transcranial electrical stimulation (TES) to improve motor and cognitive dysfunction in PD. PubMed, EMBASE, Web of Science, Google Scholar, Scopus, Library of Congress and Cochrane library were searched...
November 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29075554/oxiracetam-or-fastigial-nucleus-stimulation-reduces-cognitive-injury-at-high-altitude
#11
ShengLi Hu, JianTao Shi, Wei Xiong, WeiNa Li, LiChao Fang, Hua Feng
BACKGROUND: Cognitive impairment is common in people travelling to high altitude. Oxiracetam and electrical stimulation of cerebellar fastigial nucleus may have beneficial impacts. This study was to investigate the effects of preconditioning with Oxiracetam or fastigial nucleus stimulation (FNS) on cognitive decline following the ascension to high altitude. METHODS: The study was conducted on 60 male military voluntary members who were divided into control group, Oxiracetam group, and fastigial nucleus stimulation group...
October 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29071355/extent-of-dorsolateral-prefrontal-cortex-plasticity-and-its-association-with-working-memory-in-patients-with-alzheimer-disease
#12
Sanjeev Kumar, Reza Zomorrodi, Zaid Ghazala, Michelle S Goodman, Daniel M Blumberger, Amay Cheam, Corinne Fischer, Zafiris J Daskalakis, Benoit H Mulsant, Bruce G Pollock, Tarek K Rajji
Importance: The extent of dorsolateral prefrontal cortex (DLPFC) plasticity in Alzheimer disease (AD) and its association with working memory are not known. Objectives: To determine whether participants with AD had impaired DLPFC plasticity compared with healthy control participants, to compare working memory between participants with AD and controls, and to determine whether DLPFC plasticity was associated with working memory. Design, Setting, and Participants: This cross-sectional study included 32 participants with AD who were 65 years or older and met diagnostic criteria for dementia due to probable AD with a score of at least 17 on the Mini-Mental State Examination and 16 age-matched control participants...
October 25, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/29068982/delayed-recovery-of-the-affected-finger-extensors-at-chronic-stage-in-a-stroke-patient-a-case-report
#13
Sung Ho Jang, Han Do Lee
RATIONALE: A 33-year-old male presented with complete weakness of the right extremities due to corona radiata infarct. PATIENT CONCERNS: The main concerns of the patient is recovery of hand function especially related to finger extension. DIAGNOSES: Right corona radiata infarct. INTERVENTIONS: He underwent physical therapy and occupational therapy at the outpatient clinic of the rehabilitation department of the same university hospital until 2 years after onset...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29067749/combined-brain-and-peripheral-nerve-stimulation-in-chronic-stroke-patients-with-moderate-to-severe-motor-impairment
#14
Isabella S Menezes, Leonardo G Cohen, Eduardo A Mello, André G Machado, Paul Hunter Peckham, Sarah M Anjos, Inara L Siqueira, Juliana Conti, Ela B Plow, Adriana B Conforto
OBJECTIVES: To evaluate effects of somatosensory stimulation in the form of repetitive peripheral nerve sensory stimulation (RPSS) in combination with transcranial direct current stimulation (tDCS), tDCS alone, RPSS alone, or sham RPSS + tDCS as add-on interventions to training of wrist extension with functional electrical stimulation (FES), in chronic stroke patients with moderate to severe upper limb impairments in a crossover design. We hypothesized that the combination of RPSS and tDCS would enhance the effects of FES on active range of movement (ROM) of the paretic wrist to a greater extent than RPSS alone, tDCS alone or sham RPSS + tDCS...
October 25, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29065603/safety-of-the-transcranial-focal-electrical-stimulation-via-tripolar-concentric-ring-electrodes-for-hippocampal-ca3-subregion-neurons-in-rats
#15
Samuel Mucio-Ramírez, Oleksandr Makeyev
Epilepsy is a neurological disorder that affects approximately one percent of the world population. Noninvasive electrical brain stimulation via tripolar concentric ring electrodes has been proposed as an alternative/complementary therapy for seizure control. Previous results suggest its efficacy attenuating acute seizures in penicillin, pilocarpine-induced status epilepticus, and pentylenetetrazole-induced rat seizure models and its safety for the rat scalp, cortical integrity, and memory formation. In this study, neuronal counting was used to assess possible tissue damage in rats (n = 36) due to the single dose or five doses (given every 24 hours) of stimulation on hippocampal CA3 subregion neurons 24 hours, one week, and one month after the last stimulation dose...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29064955/modulation-of-short-latency-afferent-inhibition-and-short-interval-intracortical-inhibition-by-test-stimulus-intensity-and-motor-evoked-potential-amplitude
#16
Shota Miyaguchi, Sho Kojima, Ryoki Sasaki, Hiroyuki Tamaki, Hideaki Onishi
The present study aimed to investigate the effects of changes in motor-evoked potential (MEP) amplitude on short-latency afferent inhibition (SAI) and short-interval intracortical inhibition (SICI). MEPs in response to transcranial magnetic stimulation (TMS) of the left primary motor cortex were measured from the right first dorsal interosseous muscle of 10 healthy participants. SAI was evaluated by measuring MEPs in response to variable-intensity test TMS pulses delivered 22 ms following electrical stimulation of the right ulnar nerve (intensity fixed at the motor threshold)...
December 13, 2017: Neuroreport
https://www.readbyqxmd.com/read/29060274/a-computational-study-on-effect-of-a-transcranial-channel-as-a-skull-brain-interface-in-the-conventional-rectangular-patch-type-transcranial-direct-current-stimulation
#17
Hyeon Seo, Hyoung-Ihl Kim, Sung Chan Jun
A conceptual model of a transcranial channel was recently proposed for conveying external currents of the skull to the brain; the effects of the transcranial channel combined with high-definition transcranial direct current stimulation (HD-tDCS) was investigated, resulting in discovery of increased stimulus intensity and focality. In this work, rather than HD-tDCS using smaller disc-type electrodes, we proposed the use of the transcranial channel with conventional tDCS using larger patch electrodes. We used multi-scale computational models that couple an anatomically realistic head model with multi-compartmental models of cortical neurons...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060150/electric-field-characteristics-of-low-field-synchronized-transcranial-magnetic-stimulation-stms
#18
Zhi-De Deng, Sarah H Lisanby
Low-field synchronized trancranial magnetic stimulation (sTMS) was hypothesized to have significant therapeutic effects in patients with major depressive disorder by entrainment of neural oscillations. The sTMS device is comprised of neodymium magnets mounted over multiple brain regions and set to rotate at the patients alpha frequency. We characterized the electric field strength and distribution of sTMS using the finite element method. We found that the maximum induced electric field strength on the surfaces of the head and cortex are approximately 0...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060149/estimates-of-peak-electric-fields-induced-by-transcranial-magnetic-stimulation-in-pregnant-women-as-patients-using-an-fem-full-body-model
#19
J Yanamadala, G M Noetscher, S N Makarov, A Pascual-Leone
Transcranial magnetic stimulation (TMS) for treatment of depression during pregnancy is an appealing alternative to fetus-threatening drugs. However, no studies to date have been performed that evaluate the safety of TMS for a pregnant mother patient and her fetus. A full-body FEM model of a pregnant woman with about 100 tissue parts has been developed specifically for the present study. This model allows accurate computations of induced electric field in every tissue given different locations of a shape-eight coil, a biphasic pulse, common TMS pulse durations, and using different values of the TMS intensity measured in SMT (Standard Motor Threshold) units...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060075/optimal-inter-stimulus-interval-for-paired-associative-stimulation-with-mechanical-stimulation
#20
Euisun Kim, Minoru Shinohara, Jun Ueda
In this paper, inter-stimulus interval (ISI) of paired associative stimulation (PAS) with mechanical stimulation was analyzed. PAS is a prominent therapeutic intervention for individuals after stroke and helps to improve limb function by strengthening excitatory synapses and inducing neural plasticity. This intervention involves repeated application of transcranial magnetic stimulation (TMS) followed by peripheral stimulation. When responses to both stimulations are overlapped in the brain at the same time, this successful PAS is expected to induce long term potentiation (LTP) which leads to a neural plasticity phenomenon...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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