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https://www.readbyqxmd.com/read/28231639/cell-cycle-rna-regulons-coordinating-early-lymphocyte-development
#1
REVIEW
Alison Galloway, Martin Turner
Lymphocytes undergo dynamic changes in gene expression as they develop from progenitor cells lacking antigen receptors, to mature cells that are prepared to mount immune responses. While transcription factors have established roles in lymphocyte development, they act in concert with post-transcriptional and post-translational regulators to determine the proteome. Furthermore, the post-transcriptional regulation of RNA regulons consisting of mRNAs whose protein products act cooperatively allows RNA binding proteins to exert their effects at multiple points in a pathway...
February 23, 2017: Wiley Interdisciplinary Reviews. RNA
https://www.readbyqxmd.com/read/28231140/food-safety-recommendations-for-determining-doneness-in-consumer-egg-dish-recipes-and-measurement-of-endpoint-temperatures-when-recipes-are-followed
#2
Sandria Godwin, Curtis Maughan, Edgar Chambers
Many consumers do not follow recommended food safety practices for cooking egg dishes, such as pies, quiches, and casseroles, potentially leading to foodborne illnesses such as Salmonellosis. The United States Department of Agriculture (USDA) recommends cooking egg mixtures until the center reaches 71 °C (160 °F). The objectives of this study were to determine what endpoint temperature information consumers receive from egg dish recipes, and if recipes would lead to safe temperatures when followed. Egg dish recipes (n = 226) from 65 websites, 50 cookbooks, and nine magazine titles (multiple issues of each) were analyzed...
June 23, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28230614/characteristics-of-providers-performing-urogynecologic-procedures-on-medicare-patients-2012-2014
#3
Daniel E Stone, Benjamin J Barenberg, Stephanie D Pickett, Dena E OʼLeary, Lieschen H Quiroz
OBJECTIVE: To analyze the characteristics of providers performing stress urinary incontinence (SUI) and pelvic organ prolapse (POP) procedures in the United States. METHODS: The Centers for Medicare Services public database, released for years 2012 through 2014, was queried for SUI-related and POP-related Healthcare Common Procedure Coding System. Providers were categorized as Female Pelvic Medicine and Reconstructive Surgery (FPMRS) providers and non-FPMRS providers, using a list of FPMRS board-certified providers compiled through the American Board of Medical Subspecialties website...
March 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28229477/-why-not-you-discourses-of-widening-access-on-uk-medical-school-websites
#4
Kirsty Alexander, Tania Fahey Palma, Sandra Nicholson, Jennifer Cleland
CONTEXT: In the UK, applications to medicine from those in lower socio-economic groups remain low despite significant investments of time, interest and resources in widening access (WA) to medicine. This suggests that medical schools' core messages about WA may be working to embed or further reinforce marginalisation, rather than to combat this. Our objective was to investigate how the value of WA is communicated by UK medical schools through their websites, and how this may create expectations regarding who is 'suitable' for medicine...
February 22, 2017: Medical Education
https://www.readbyqxmd.com/read/28229295/benchmarking-of-venous-thromboembolism-prophylaxis-practice-with-ent-uk-guidelines
#5
Ali S Al-Qahtani
The aim of this study was to benchmark our guidelines of prevention of venous thromboembolism (VTE) in ENT surgical population against ENT.UK guidelines, and also to encourage healthcare providers to utilize benchmarking as an effective method of improving performance. The study design is prospective descriptive analysis. The setting of this study is tertiary referral centre (Assir Central Hospital, Abha, Saudi Arabia). In this study, we are benchmarking our practice guidelines of the prevention of VTE in the ENT surgical population against that of ENT...
February 22, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28229275/a-pilot-randomized-trial-to-prevent-sexual-dysfunction-in-postmenopausal-breast-cancer-survivors-starting-adjuvant-aromatase-inhibitor-therapy
#6
Pragati Advani, Abenaa M Brewster, George P Baum, Leslie R Schover
PURPOSE: A randomized pilot trial evaluated the hypothesis that early intervention lessens sexual dysfunction in the first year on aromatase inhibitors. A secondary aim was comparing the efficacy of two vaginal moisturizers. METHODS: Fifty-seven postmenopausal women with early stage breast cancer starting aromatase inhibitors were randomized to three treatment groups. All received a handout on managing sexual and other side effects. The Usual Care group received no additional therapy...
February 22, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28228646/readability-credibility-and-quality-of-patient-information-for-hypogonadism-and-testosterone-replacement-therapy-on-the-internet
#7
J A McBride, C C Carson, R M Coward
The incidence of hypogonadism and use of testosterone replacement therapy (TRT) are rising, while data evaluating the complexity and quality of health-care information available to patients on the Internet for hypogonadism or TRT are lacking. This study focuses on characterizing the readability, credibility and quality of patient-centered information for hypogonadism on the Internet. A Google search was performed to identify top-ranked websites offering patient-centered information on hypogonadism and TRT. Readability was quantified by reading grade level using several validated instruments...
February 23, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28228368/a-web-based-physical-activity-intervention-for-spanish-speaking-latinas-a-costs-and-cost-effectiveness-analysis
#8
Britta Larsen, Bess Marcus, Dori Pekmezi, Sheri Hartman, Todd Gilmer
BACKGROUND: Latinas report particularly low levels of physical activity and suffer from greater rates of lifestyle-related conditions such as obesity and diabetes. Interventions are needed that can increase physical activity in this growing population in a large-scale, cost-effective manner. Web-based interventions may have potential given the increase in Internet use among Latinas and the scalability of Web-based programs. OBJECTIVE: To examine the costs and cost-effectiveness of a Web-based, Spanish-language physical activity intervention for Latinas compared to a wellness contact control...
February 22, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28228064/a-mapping-study-on-the-internet-and-suicide
#9
Karolina Krysinska, Michael Westerlund, Thomas Niederkrotenthaler, Karl Andriessen, Vladimir Carli, Gergö Hadlaczky, Benedikt Till, Danuta Wasserman
BACKGROUND: Since the mid-1990s concerns have been raised regarding the possible links between suicide and the Internet, especially among adolescents and young adults. AIMS: To identify the nature and extent of the scientific publications, especially original research studies, on suicide and the Internet, and to investigate how the field has developed over time. In particular, this mapping study looks at types of publications, topic areas, focus of original research papers, and suicide-related variables of interest in publications...
February 23, 2017: Crisis
https://www.readbyqxmd.com/read/28226024/-guidelines-for-accurate-and-transparent-health-estimates-reporting-the-gather-statement
#10
Gretchen A Stevens, Leontine Alkema, Robert E Black, J Ties Boerma, Gary S Collins, Majid Ezzati, John T Grove, Daniel R Hogan, Margaret C Hogan, Richard Horton, Joy E Lawn, Ana Marušic, Colin D Mathers, Christopher J L Murray, Igor Rudan, Joshua A Salomon, Paul J Simpson, Theo Vos, Vivian Welch
Measurements of health indicators are rarely available for every population and period of interest, and available data may not be comparable. The Guidelines for Accurate and Transparent Health Estimates Reporting (GATHER) define best reporting practices for studies that calculate health estimates for multiple populations (in time or space) using multiple information sources. Health estimates that fall within the scope of GATHER include all quantitative population-level estimates (including global, regional, national, or subnational estimates) of health indicators, including indicators of health status, incidence and prevalence of diseases, injuries, and disability and functioning; and indicators of health determinants, including health behaviours and health exposures...
January 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28225416/table-of-contents-for-online-material-in-the-march-2017-issue
#11
(no author information available yet)
Abstracts or summaries of online content are printed in every issue of Obstetrics & Gynecology in this section. The complete documents can be found on our website, www.greenjournal.org. The specific URL for the content in this section is printed at the end of the abstract or summary.
March 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28225349/temporal-trends-in-chronic-obstructive-pulmonary-disease-mortality-in-mexico-1999-2014
#12
E Hernández-Garduño, H L Ocaña-Servín
SETTING: Country of Mexico. OBJECTIVE: To determine mortality trends due to chronic obstructive pulmonary disease (COPD) in Mexico between 1999 and 2014. DESIGN: COPD mortality data for persons aged ≥40 years from 1999 to 2014 were obtained from the official website of the Mexican Ministry of Health. Age-standardised mortality rates (ASMRs) were calculated, and joinpoint regression analysis was used to identify trends over time. The annual per cent change (APC) was determined for each trend...
March 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28225316/adverse-event-reporting-in-patients-treated-with-thyroid-hormone-extract
#13
Rupendra T Shrestha, Alan Malabanan, Bryan R Haugen, Elliott G Levy, James V Hennessey
OBJECTIVE: Thyroid hormone extract is used for the treatment of thyroid disorders but limited data exist on adverse events commonly noted by the physicians associated with this use. The purpose of this survey was to report adverse events observed by expert physicians managing patients treated for thyroid disease with thyroid hormones. METHODS: Members of the American Thyroid Association, The Endocrine Society and the American Association of Clinical Endocrinologists developed a survey instrument modeled on the FDA's reported adverse events for levothyroxine that would effectively assess the clinical experience of frequent prescribers of thyroid hormone...
February 22, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28224347/emergency-medical-service-systems-in-sri-lanka-problems-of-the-past-challenges-of-the-future
#14
Kelum Wimalaratne, Jeong Il Lee, Kang Hyun Lee, Hee Young Lee, Jung Hun Lee, In Hye Kang
INTRODUCTION: The concept of emergency medical services (EMS) is new to Sri Lanka. This article describes the development, delivery, and future ideas for EMS in Sri Lanka. Sri Lanka also faces frequent natural hazards that justify the establishment of an EMS service. METHODOLOGY: Data and information regarding emergency medical care in Sri Lanka were collected and reviewed from resources including websites and research papers. RESULTS: Currently, there are no qualified emergency medical physicians in Sri Lanka...
December 2017: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28224133/dataset-on-the-learning-performance-of-ecdl-digital-skills-of-undergraduate-students-for-comparing-educational-gaming-gamification-and-social-networking
#15
Luis de-Marcos, Eva García-López, Antonio García-Cabot
This paper reports data about the learning performance of students using four different motivational tools: an educational game, a gamified plugin, a social networking website and a gamified social networking website. It also reports a control group. The data pertain to 379 students of an undergraduate course that covers basic Information and Communication Technology (ICT) skills in Spain. Data corresponds to different learning modules of the European Computer Driving License (ECDL) initiative. The data include variables of four pre-test scores, four post-test scores and a final examination...
April 2017: Data in Brief
https://www.readbyqxmd.com/read/28222975/-activities-using-websites-and-social-networks-tools-and-indicators-for-evaluation
#16
María José López, Xavier Continente, Esther Sánchez, Montse Bartroli
In the field of health, information and communication technology (ICT) can create a space that, regardless of place or time, enables information to be shared and disseminated quickly. In addition to the usual challenges of evaluating public health activities, other difficulties are present when evaluating activities using ICT, such as lack of previous standards, unknown individual exposure or lack of information on the characteristics of those exposed. The aim of this paper is to describe some tools and indicators that may help to assess the scope, use and parameters related to website positioning on search engines as well as the connected social networks...
February 18, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28222885/the-influence-of-lip-form-on-incisal-display-with-lips-in-repose-on-the-esthetic-preferences-of-dentists-and-lay-people
#17
Jee Kim, Richard Topolski, Douglas Dickinson, Van Ramos
STATEMENT OF PROBLEM: Information is lacking for viewer preferences for incisal display with lips in repose. PURPOSE: The purpose of this online survey was to establish measurement parameters to classify and define a lip form and to evaluate the influence of lip form on dentists' and laypersons' preferences for the amount of incisal display with lips in repose. MATERIAL AND METHODS: Computer-generated male and female models were created using 3 different lip forms each, straight, moderate, and high...
February 17, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28222793/corporate-social-responsibility-to-improve-access-to-medicines-the-case-of-brazil
#18
Halla Thorsteinsdóttir, Natasha Ovtcharenko, Jillian Clare Kohler
BACKGROUND: Access to medicines and the development of a strong national pharmaceutical industry are two longstanding pillars of health policy in Brazil. This is reflected in a clear emphasis by Brazil's Federal Government on improving access to medicine in national health plans and industrial policies aimed at promoting domestic pharmaceutical development. This research proposes that such policies may act as incentives for companies to pursue a strategic Corporate Social Responsibility (CSR) agenda...
February 21, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28222341/patient-emotions-and-perceptions-of-antiepileptic-drug-changes-and-titration-during-treatment-for-epilepsy
#19
Jesse Fishman, Greg Cohen, Colin Josephson, Ann Marie Collier, Srikanth Bharatham, Ying Zhang, Imane Wild
OBJECTIVE: To investigate the impact of antiepileptic drug (AED) change and dose titration on the emotional well-being of patients with epilepsy. METHODS: Members of an online epilepsy community were invited to voluntarily participate in an online survey. The cross-sectional anonymous survey consisted of 31 multiple choice questions balanced in terms of variety and positivity/negativity of emotions concerning participants' most recent AED change. To substantiate survey results, spontaneous comments from epilepsy-related online forums and social media websites that mentioned participants' experiences with AED medication changes (termed passive listening statements) were analyzed and categorized by theme...
February 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28222220/meaningful-endpoints-for-therapies-approved-for-hematologic-malignancies
#20
B Douglas Smith, Amy E DeZern, Alex W Bastian, Brian G M Durie
BACKGROUND: Overall survival (OS) is considered the gold standard for determining treatment efficacy in oncology trials, but the relation between treatment and OS can be challenging to assess because of long study durations and the impact of subsequent therapies on outcome. Using OS can be particularly difficult for new therapies in hematologic malignancies (HMs). METHODS: This retrospective analysis was conducted to characterize the primary endpoints used to support US Food and Drug Administration (FDA) approvals for new drug or novel HM indications between January 2002 and July 2015...
February 21, 2017: Cancer
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