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https://www.readbyqxmd.com/read/28816077/in-vitro-evaluation-of-the-occlusive-properties-of-the-artventive-eos-occlusion-device-for-transrenal-ureteral-occlusion
#1
Daniel Kuetting, Carsten Meyer, Hans Heinz Schild, Claus Christian Pieper
PURPOSE: Current techniques for percutaneous ureteral occlusion are either technically difficult or not satisfactory due to frequent ureteral recanalization. The purpose of this in vitro study was to evaluate the occlusive properties of an "off the shelf" solution (EOS; ArtVentive Medical Group, Inc, Carlsbad, CA/USA) for transrenal ureteral occlusion. MATERIALS AND METHODS: 8 and 11 mm ePTFE covered ArtVentive EOS devices were used in 10 porcine models. Experiments were performed in explanted porcine ureters to simulate physiologic conditions...
August 17, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28802449/living-with-an-autonomous-spatiotemporal-home-heating-system-exploration-of-the-user-experiences-ux-through-a-longitudinal-technology-intervention-based-mixed-methods-approach
#2
Martin Kruusimagi, Sarah Sharples, Darren Robinson
Rising energy demands place pressure on domestic energy consumption, but savings can be delivered through home automation and engaging users with their heating and energy behaviours. The aim of this paper is to explore user experiences (UX) of living with an automated heating system regarding experiences of control, understanding of the system, emerging thermal behaviours, and interactions with the system as this area is not sufficiently researched in the existing homes setting through extended deployment. We present a longitudinal deployment of a quasi-autonomous spatiotemporal home heating system in three homes...
November 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28649906/a-test-for-a-difference-in-the-associability-of-blocked-and-uninformative-cues-in-human-predictive-learning
#3
Metin Uengoer, Dominic M Dwyer, Stephan Koenig, John M Pearce
In human predictive learning, blocking, A+AB+, and a simple discrimination, UX+ VX-, result in a stronger response to the blocked, B, than the uninformative cue, X (where letters represent cues, and + and - represent different outcomes). In order to assess if these different treatments result in more attention being paid to blocked than uninformative cues, Stage 1 in each of three experiments generated two blocked cues, B and E, and two uninformative cues, X and Y. In Stage 2, participants received two simple discriminations: either BX+ EX- and BY+ EY-, or BX+ BY- and EX+ EY-...
June 25, 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/28535196/characterization-of-antixenosis-in-soybean-genotypes-to-bemisia-tabaci-hemiptera-aleyrodidae-biotype-b
#4
E L L Baldin, P L Cruz, R Morando, I F Silva, J P F Bentivenha, L R S Tozin, T M Rodrigues
Bemisia tabaci biotype B (Gennadius) is one of the most important soybean pest worldwide. Herein, 15 soybean genotypes were evaluated, to characterize the occurrence of antixenosis to B. tabaci biotype B. Initially, a multiple-choice test with all genotypes was carried out, evaluating the settling and oviposition preference at 3 d after infestation, and the colonization by nymphs after 48 d of infestation. Subsequently, a no-choice test, using 14 genotypes, was conducted with infested plants individually, and the number of eggs was counted after 72 h...
May 23, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28526667/patient-centered-decision-support-formative-usability-evaluation-of-integrated-clinical-decision-support-with-a-patient-decision-aid-for-minor-head-injury-in-the-emergency-department
#5
Edward R Melnick, Erik P Hess, George Guo, Maggie Breslin, Kevin Lopez, Anthony J Pavlo, Fuad Abujarad, Seth M Powsner, Lori A Post
BACKGROUND: The Canadian Computed Tomography (CT) Head Rule, a clinical decision rule designed to safely reduce imaging in minor head injury, has been rigorously validated and implemented, and yet expected decreases in CT were unsuccessful. Recent work has identified empathic care as a key component in decreasing CT overuse. Health information technology can hinder the clinician-patient relationship. Patient-centered decision tools to support the clinician-patient relationship are needed to promote evidence-based decisions...
May 19, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28490701/-adeabc-efflux-pump-and-resistance-of-acinetobacter-baumannii-against-carbapenem
#6
Qingya Dou, Mingxiang Zou, Jun Li, Haichen Wang, Yongmei Hu, Wen'en Liu
To investigate relationship between AdeABC efflux pump and resistance of Acinetobacter baumannii against carbapenem.
 Methods: Carbapenem-resistant strains were acquired from multistep selection resistance test by meropenem in vitro. The quantitation test for sensitivities of strains before and after induction was determined by the E-test, and carbonylcyanide-m-chlorophenylhydrazone (CCCP) inhibition test was used to screen efflux pump. PCR, sequencing analysis, or real-time PCR was used to analyze the changes of regulatory genes adeR and adeS of the AdeABC efflux pump system, or expressions of adeA, adeB, adeR, and adeS in the strains before and after induction, respectively...
April 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28464263/urised-3-and-ux-2000-automated-urine-sediment-analyzers-vs-manual-microscopic-method-a-comparative-performance-analysis
#7
Sathima Laiwejpithaya, Preechaya Wongkrajang, Kanit Reesukumal, Chonticha Bucha, Suriya Meepanya, Chanutchaya Pattanavin, Varanya Khejonnit, Achara Chuntarut
BACKGROUND: Fully automated urine analyzers now play an important role in routine urinalysis in most laboratories. The recently introduced UriSed 3 has a new automated digital imaging urine sediment analyzer with a phase contrast feature. The aim of this study was to compare the performance of the UriSed 3 and UX-2000 automated urine sediment analyzers with each other and with the results of the manual microscopic method. METHODS: Two hundred seventy-seven (277) samples of leftover fresh urine from our hospital's central laboratory were evaluated by two automated urine sediment analyzers-UriSed 3 and UX-2000...
May 2, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28440786/magnetic-and-transport-properties-of-a-layered-compound-ce2te5
#8
D Chen, S Zhang, H X Yang, J Q Li, G F Chen
Ce2Te5 single crystals were successfully grown using RbCl/LiCl flux method. The structure of Ce2Te5 can be viewed as a combination of CeTe2 and CeTe3. The experimental results of magnetic susceptibility [Formula: see text], isothermal magnetization M(H), electrical resistivity [Formula: see text], and heat capacity C(T) show two clear anomalies at 5.1 and 2.3 K, which correspond to a ferrimagnetic and a possible antiferromagnetic transition, respectively. Both of [Formula: see text] and C(T) confirm a third transition at 0...
July 5, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28296319/validation-of-the-calypso-surface-beacon-transponder
#9
Maxwell Belanger, Ziad Saleh, Tom Volpe, Rich Margiasso, Xiang Li, Maria Chan, Xiaofeng Zhu, Xiaoli Tang
Calypso L-shaped Surface Beacon transponder has recently become available for clinical applications. We herein conduct studies to validate the Surface Beacon transponder in terms of stability, reproducibility, orientation sensitivity, cycle rate dependence, and respiratory waveform tracking accuracy. The Surface Beacon was placed on a Quasar respiratory phantom and positioned at the isocenter with its two arms aligned with the lasers. Breathing waveforms were simulated, and the motion of the transponder was tracked...
July 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28269687/stayfit-a-wearable-application-for-gym-based-power-training
#10
Maram Maheedhar, Aman Gaurav, Vivek Jilla, Vijay N Tiwari, Rangavittal Narayanan
Comprehensive fitness training involves both cardiorespiratory and power components. Often power/muscle strength training is confused with cardiorespiratory endurance training. However, each of them target different physiological aspects of fitness. Although, wearable based fitness trackers designed towards cardiorespiratory endurance training are available in the market, a dedicated wearable based fitness application designed for power training/tracking is still not readily available to fitness enthusiasts...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28239338/differential-neural-responses-underlying-the-inhibition-of-the-startle-response-by-pre-pulses-or-gaps-in-mice
#11
Rocio Moreno-Paublete, Barbara Canlon, Christopher R Cederroth
Gap pre-pulse inhibition of the acoustic startle (GPIAS) is a behavioral paradigm used for inferring the presence of tinnitus in animal models as well as humans. In contrast to pre-pulse inhibition (PPI), the neural circuitry controlling GPIAS is poorly understood. To increase our knowledge on GPIAS, a comparative study with PPI was performed in mice combining these behavioral tests and c-Fos activity mapping in brain areas involved in the inhibition of the acoustic startle reflex (ASR). Both pre-pulses and gaps efficiently inhibited the ASR and abolished the induction of c-Fos in the pontine reticular nucleus...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28227948/stayfit-a-wearable-application-for-gym-based-power-training
#12
Maram Maheedhar, Aman Gaurav, Vivek Jilla, Vijay N Tiwari, Rangavittal Narayanan, Maram Maheedhar, Aman Gaurav, Vivek Jilla, Vijay N Tiwari, Rangavittal Narayanan, Rangavittal Narayanan, Vijay N Tiwari, Vivek Jilla, Aman Gaurav, Maram Maheedhar
Comprehensive fitness training involves both cardiorespiratory and power components. Often power/muscle strength training is confused with cardiorespiratory endurance training. However, each of them target different physiological aspects of fitness. Although, wearable based fitness trackers designed towards cardiorespiratory endurance training are available in the market, a dedicated wearable based fitness application designed for power training/tracking is still not readily available to fitness enthusiasts...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28188739/comparison-of-automated-devices-ux-2000-and-sedimax-autionmax-for-urine-samples-screening-a-multicenter-spanish-study
#13
MULTICENTER STUDY
Catalina Sánchez-Mora, Delia Acevedo, Maria Amelia Porres, Ana María Chaqués, Javier Zapardiel, Aurelia Gallego-Cabrera, Jose María López, Jose María Maesa
OBJECTIVES: In this study we aim to compare UX2000 (Sysmex Corp, Japan) and SediMAX/AutionMax (Arkray Factory Inc., Japan), totally automatized analyzers, against Fuchs-Rosenthal counting chamber, the gold standard technique for sediment analysis. DESIGN AND METHODS: Urine samples of 1454 patients from three Spanish hospitals were assessed for red and white blood cells (RBC; WBC) using three different techniques: flow cytometry, image-based method and Fuchs-Rosenthal counting chamber...
August 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28167935/antifungal-therapy-new-advances-in-the-understanding-and-treatment-of-mycosis
#14
REVIEW
Liliana Scorzoni, Ana C A de Paula E Silva, Caroline M Marcos, Patrícia A Assato, Wanessa C M A de Melo, Haroldo C de Oliveira, Caroline B Costa-Orlandi, Maria J S Mendes-Giannini, Ana M Fusco-Almeida
The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds. Additionally, identifying novel drug targets is challenging because there are many similarities between fungal and human cells. The most common antifungal targets include fungal RNA synthesis and cell wall and membrane components, though new antifungal targets are being investigated. Nonetheless, fungi have developed resistance mechanisms, such as overexpression of efflux pump proteins and biofilm formation, emphasizing the importance of understanding these mechanisms...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28134800/immune-modulation-by-androgen-deprivation-and-radiation-therapy-implications-for-prostate-cancer-immunotherapy
#15
REVIEW
Jennifer L Kalina, David S Neilson, Alexandra P Comber, Jennifer M Rauw, Abraham S Alexander, Joanna Vergidis, Julian J Lum
Prostate cancer patients often receive androgen deprivation therapy (ADT) in combination with radiation therapy (RT). Recent evidence suggests that both ADT and RT have immune modulatory properties. First, ADT can cause infiltration of lymphocytes into the prostate, although it remains unclear whether the influx of lymphocytes is beneficial, particularly with the advent of new classes of androgen blockers. Second, in rare cases, radiation can elicit immune responses that mediate regression of metastatic lesions lying outside the field of radiation, a phenomenon known as the abscopal response...
January 27, 2017: Cancers
https://www.readbyqxmd.com/read/27999567/e%C3%AF-ux-in-the-oral-metagenome-the-discovery-of-a-novel-tetracycline-and-tigecycline-abc-transporter
#16
Liam J Reynolds, Adam P Roberts, Muna F Anjum
Antibiotic resistance in human bacterial pathogens and commensals is threatening our ability to treat infections and conduct common medical procedures. As novel antibiotics are discovered and marketed it is important that we understand how resistance to them may arise and know what environments may act as reservoirs for such resistance genes. In this study a tetracycline and tigecycline resistant clone was identified by screening a human saliva metagenomic library in Escherichia coli EPI300 on agar containing 5 μg/ml tetracycline...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27897000/identifying-cancer-specific-metabolic-signatures-using-constraint-based-models
#17
A Schultz, S Mehta, C W Hu, F W Hoff, T M Horton, S M Kornblau, A A Qutub
Cancer metabolism differs remarkably from the metabolism of healthy surrounding tissues, and it is extremely heterogeneous across cancer types. While these metabolic differences provide promising avenues for cancer treatments, much work remains to be done in understanding how metabolism is rewired in malignant tissues. To that end, constraint-based models provide a powerful computational tool for the study of metabolism at the genome scale. To generate meaningful predictions, however, these generalized human models must first be tailored for specific cell or tissue sub-types...
2016: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/27895581/evaluation-of-near-infrared-dyes-as-markers-of-p-glycoprotein-activity-in-tumors
#18
Inessa Semenenko, Emma Portnoy, Mohammed Aboukaoud, Serge Guzy, Miriam Shmuel, Gal Itzhak, Sara Eyal
Aim: The multidrug resistance protein 1 (MDR1; P-glycoprotein) has been associated with efflux of chemotherapeutic agents from tumor cells and with poor patient prognosis. This study evaluated the feasibility of non-invasive, non-radioactive near infrared (NIR) imaging methodology for detection of MDR1 functional activity in tumors. Methods: Initial accumulation assays were conducted in MDR1-overexpressing MDCK cells (MDCK-MDR1) and control MDCK cells (MDCK-CT) using the NIR dyes indocyanine green (ICG), IR-783, IR-775, rhodamine 800, XenoLight DiR, and Genhance 750, at 0...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27822201/a-tolc-like-protein-of-actinobacillus-pleuropneumoniae-is-involved-in-antibiotic-resistance-and-biofilm-formation
#19
Ying Li, Sanjie Cao, Luhua Zhang, Gee W Lau, Yiping Wen, Rui Wu, Qin Zhao, Xiaobo Huang, Qigui Yan, Yong Huang, Xintian Wen
Actinobacillus pleuropneumoniae is the etiologic agent of porcine contagious pleuropneumonia, a significant disease that causes serious economic losses to the swine industry worldwide. Persistent infections caused by bacterial biofilms are recalcitrant to treat because of the particular drug resistance of biofilm-dwelling cells. TolC, a key component of multidrug efflux pumps, are responsible for multidrug resistance (MDR) in many Gram-negative bacteria. In this study, we identified two TolC-like proteins, TolC1 and TolC2, in A...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27741494/micro-ct-based-finite-element-models-of-cancellous-bone-predict-accurately-displacement-once-the-boundary-condition-is-well-replicated-a-validation-study
#20
Yuan Chen, Enrico Dall Ara, Erika Sales, Krishnagoud Manda, Robert Wallace, Pankaj Pankaj, Marco Viceconti
Non-destructive 3D micro-computed tomography (microCT) based finite element (microFE) models are used to estimate bone mechanical properties at tissue level. However, their validation remains challenging. Recent improvements in the quantification of displacements in bone tissue biopsies subjected to staged compression, using refined Digital Volume Correlation (DVC) techniques, now provide a full field displacement information accurate enough to be used for microFE validation. In this study, three specimens (two humans and one bovine) were tested with two different experimental set-ups, and the resulting data processed with the same DVC algorithm...
January 2017: Journal of the Mechanical Behavior of Biomedical Materials
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