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https://www.readbyqxmd.com/read/28318234/light-absorbing-brown-carbon-aerosol-constituents-from-combustion-of-indonesian-peat-and-biomass
#1
Sri Hapsari Budisulistiorini, Matthieu Riva, Michael Williams, Jing Chen, Masayuki Itoh, Jason Douglas Surratt, Mikinori Kuwata
Light-absorbing brown carbon (BrC) constituents of organic aerosol (OA) have been shown to significantly absorb ultra-violet (UV) and visible light, and thus, impact radiative forcing. However, molecular identification of the BrC constituents is still limited. In this study, we characterize BrC constituents at the molecular level in: i) aerosols emitted by combustion of peat, fern/leaf, and charcoal from Indonesia and ii) ambient aerosols collected in Singapore during the 2015 haze episode. Aerosols were analyzed using ultra-performance liquid chromatography interfaced to a diode array detector and electrospray ionization high-resolution quadrupole time-of-flight mass spectrometer (UPLC/DAD-(-)ESI-HR-QTOFMS) operated in the negative ion mode...
March 20, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28317499/a-multi-country-study-of-harms-to-children-because-of-others-drinking
#2
Anne-Marie Laslett, Georgia Rankin, Orratai Waleewong, Sarah Callinan, Hanh T M Hoang, Ramon Florenzano, Siri Hettige, Isidore Obot, Latsamy Siengsounthone, Akanidomo Ibanga, Ann Hope, Jonas Landberg, Hanh T M Vu, Thaksaphon Thamarangsi, Dag Rekve, Robin Room
OBJECTIVE: This study aims to ascertain and compare the prevalence and correlates of alcohol-related harms to children cross-nationally. METHOD: National and regional sample surveys of randomly selected households included 7,848 carers (4,223 women) from eight countries (Australia, Chile, Ireland, Lao People's Democratic Republic [PDR], Nigeria, Sri Lanka, Thailand, and Vietnam). Country response rates ranged from 35% to 99%. Face-to-face or telephone surveys asking about harm from others' drinking to children ages 0-17 years were conducted, including four specific harms: that because of others' drinking in the past year children had been (a) physically hurt, (b) verbally abused, (c) exposed to domestic violence, or (d) left unsupervised...
March 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28306298/accurate-x-ray-spectral-predictions-an-advanced-self-consistent-field-approach-inspired-by-many-body-perturbation-theory
#3
Yufeng Liang, John Vinson, Sri Pemmaraju, Walter S Drisdell, Eric L Shirley, David Prendergast
Constrained-occupancy delta-self-consistent-field (ΔSCF) methods and many-body perturbation theories (MBPT) are two strategies for obtaining electronic excitations from first principles. Using the two distinct approaches, we study the O 1s core excitations that have become increasingly important for characterizing transition-metal oxides and understanding strong electronic correlation. The ΔSCF approach, in its current single-particle form, systematically underestimates the pre-edge intensity for chosen oxides, despite its success in weakly correlated systems...
March 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28303971/magnetowetting-of-ferrofluidic-thin-liquid-films
#4
Srinivas Tenneti, Sri Ganesh Subramanian, Monojit Chakraborty, Gaurav Soni, Sunando DasGupta
An extended meniscus of a ferrofluid solution on a silicon surface is subjected to axisymmetric, non-uniform magnetic field resulting in significant forward movement of the thin liquid film. Image analyzing interferometry is used for accurate measurement of the film thickness profile, which in turn, is used to determine the instantaneous slope and the curvature of the moving film. The recorded video, depicting the motion of the film in the Lagrangian frame of reference, is analyzed frame by frame, eliciting accurate information about the velocity and acceleration of the film at any instant of time...
March 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28302413/characterization-of-daboia-russelii-and-naja-naja-venom-neutralizing-ability-of-an-undocumented-indigenous-medication-in-sri-lanka
#5
Madhushika M Silva, Sampath S Seneviratne, Devaka K Weerakoon, Charitha L Goonasekara
BACKGROUND: Indigenous medicinal practice in Sri Lanka talks about powerful compounds extracted from native plants for treating venomous snake bites which are hardly documented in literature but are used by the indigenous doctors for thousand years. OBJECTIVE: We screened the neutralizing ability of a herbal preparation practiced in indigenous medicine of Sri Lanka, consisting of Sansevieria cylindrica, Jatropha podagrica and Citrus aurantiifolia, for its ability to neutralize venom toxins of Naja naja (Common Cobra) and Daboia russelii (Russell's viper)...
March 13, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28302056/antibiotic-overuse-for-acute-respiratory-tract-infections-in-sri-lanka-a-qualitative-study-of-outpatients-and-their-physicians
#6
L Gayani Tillekeratne, Champica K Bodinayake, Thushani Dabrera, Ajith Nagahawatte, Wasantha Kodikara Arachchi, Anoji Sooriyaarachchi, Kearsley Stewart, Melissa Watt, Truls Østbye, Christopher W Woods
BACKGROUND: Acute respiratory tract infections (ARTIs) are a common reason for antibiotic overuse worldwide. We previously showed that over 80% of outpatients presenting to a tertiary care hospital in Sri Lanka with influenza-like illness received antibiotic prescriptions, although almost half were later confirmed to have influenza. The purpose of this qualitative study was to assess Sri Lankan patients' and physicians' attitudes towards ARTI diagnosis and treatment. METHODS: Semi-structured interviews were conducted with 50 outpatients with ARTIs and five physicians in the Outpatient Department (OPD) at a large, public tertiary care hospital in southern Sri Lanka...
March 16, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28301631/androgen-receptor-function-and-androgen-receptor-targeted-therapies-in-breast-cancer-a-review
#7
Miho Kono, Takeo Fujii, Bora Lim, Meghan Sri Karuturi, Debasish Tripathy, Naoto T Ueno
Importance: The androgen receptor (AR) pathway is emerging as a potential therapeutic target in breast cancer. To date, AR-targeted drugs have been approved only for treatment of prostate cancer; however, AR-targeted treatment for breast cancer is an area of active investigation. Through review of preclinical studies, retrospective clinical studies, and clinical trials, we examined the biology of AR and AR-related pathways, the potential for AR-targeted therapies in breast cancer, and potential biomarkers for AR-targeted treatments...
March 16, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28299461/efficacy-of-higher-dose-levamisole-in-maintaining-remission-in-steroid-dependant-nephrotic-syndrome
#8
Asiri S Abeyagunawardena, Umeshi Karunadasa, Heshan Jayaweera, Shenal Thalgahagoda, Sampath Tennakoon, Shamali Abeyagunawardena
OBJECTIVE: Levamisole (LEV) has been used successfully on an alternate-day regime of 2.5 mg/kg in steroid-dependant nephrotic syndrome (SDNS) to maintain remission. This pilot study was carried out between 2010 and 2015 at a single center in Sri Lanka to evaluate the efficacy of LEV prescribed at 2.5 mg/kg daily, which is double the alternate-day dose. METHODS: Sequential children with SDNS, relapsing more than twice in the preceding 12 months and previously treated with LEV and low-dose alternate-day prednisolone (0...
March 15, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28299367/ivf-in-sri-lanka-a-concise-history-of-regulatory-impasse
#9
Bob Simpson
This article outlines the development of IVF in Sri Lanka from the first successful births in the late 1990s and over the subsequent 15 years. It is based on anthropological fieldwork carried out at various points during this period. The piece focuses on the challenges entailed in achieving regulation of the new reproductive technologies against a backdrop of: (i) a bitter civil war; (ii) a complex mosaic of different religious traditions (specifically, Buddhism, Catholicism, Hinduism and Islam); and (iii) a shift towards neo-liberal marketization, particularly in relation to specialist and hi-tech medical interventions...
June 2016: Reprod Biomed Soc Online
https://www.readbyqxmd.com/read/28299020/authors-reply
#10
Sri Ramakrishnan, Balakrishnan Kannan, Aarathy Kannan, E Prasanna Venkatesan
No abstract text is available yet for this article.
January 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28293118/cyp2d6-polymorphisms-may-predict-occurrence-of-adverse-effects-to-tamoxifen-a-preliminary-retrospective-study
#11
Ishani Wickramage, Kamani Hemamala Tennekoon, Merenchi Arachchige Yasantha Ariyaratne, Asanka Sudeshini Hewage, Tharmini Sundralingam
INTRODUCTION AND AIMS: Tamoxifen is an adjuvant drug effective in treating hormone receptor - positive breast cancer. However, 30%-50% of patients relapse and many develop adverse effects, such as hot flashes and fatty liver. Allelic variations altering the activity of cytochrome P450-2D6 enzyme affect response to tamoxifen by modulating metabolism of tamoxifen into its pharmacologically active metabolite endoxifen. Although association between CYP2D6 polymorphisms and recurrence of breast cancer in patients on tamoxifen had been reported, little evidence exists on association between these polymorphisms and adverse effects to tamoxifen...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/28292724/deleterious-role-of-trace-elements-silica-and-lead-in-the-development-of-chronic-kidney-disease
#12
Starlaine Mascarenhas, Srikanth Mutnuri, Anasuya Ganguly
Chronic-Kidney-Disease of Unknown-etiology (CKDu) has been reported in developing-countries like Sri-Lanka, India and Central-America without sparing the Indian sub-district (namely Canacona) located in south-Goa. The disease etiology is unlinked to common causes of diabetes and hypertension and assumed to be environmentally induced due to its asymptomatic-nature and occurrence in groundwater relying communities. This study aimed to understand environmental risk-factors underlying CKDu-etiology using Indian sub-district (Canacona) as case-study...
March 1, 2017: Chemosphere
https://www.readbyqxmd.com/read/28292333/location-and-content-of-counselling-and-acceptance-of-postpartum-iud-in-sri-lanka
#13
Mahesh Karra, David Canning, Sorcha Foster, Iqbal H Shah, Hemantha Senanayake, U D P Ratnasiri, Ramya Priyanwada Pathiraja
BACKGROUND: The immediate postpartum IUD (PPIUD) is a long-acting, reversible method of contraception that can be used safely and effectively following a birth. To appropriately facilitate the immediate postpartum insertion of IUDs, women must be informed of the method's availability and must be counselled on its benefits and risks prior to entering the delivery room. We examine the relationship between the location and quality of antenatal counselling and women's acceptance of immediate postpartum IUD (PPIUD) in four hospitals in Sri Lanka...
March 14, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28292320/addition-of-propranolol-in-resistant-arterial-hypertension-treatment-apropriate-study-study-protocol-for-a-randomized-double-blind-placebo-controlled-trial
#14
G R Constantine, P Ranasinghe, P Weeratunga, C Weeraratne, P Galappatthy, S Rajapakse, U Senarath, P Katulanda
BACKGROUND: Resistant hypertension is defined as an uncontrolled blood pressure despite treatment at best-tolerated doses with at least three antihypertensive agents including a diuretic. It is an emerging public health problem. At present clinical trial data on management of resistant hypertension is limited. Management is largely based on observational studies and expert opinions. Propranolol is a nonselective beta blocker. Several studies have confirmed that propranolol has a significant hypotensive action, both when used alone and as an adjuvant therapy...
March 14, 2017: Trials
https://www.readbyqxmd.com/read/28291978/serious-bodily-harm-related-to-obsessions-from-sri-lanka
#15
Miyuru Chandradasa, Layani Champika, Darshani Hettiarachchi, Swarna Wijetunge, Jayan Mendis
No abstract text is available yet for this article.
March 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28289987/biochar-based-constructed-wetlands-to-treat-reverse-osmosis-rejected-concentrates-in-chronic-kidney-disease-endemic-areas-in-sri-lanka
#16
B C L Athapattu, T W L R Thalgaspitiya, U L S Yasaratne, Meththika Vithanage
The objectives were to investigate the potential remedial measures for reverse osmosis (RO) rejected water through constructed wetlands (CWs) with low-cost materials in the media established in chronic kidney disease of unknown etiology (CKDu) prevalent area in Sri Lanka. A pilot-scale surface and subsurface water CWs were established at the Medawachchiya community-based RO water supply unit. Locally available soil, calicut tile and biochar were used in proportions of 81, 16.5 and 2.5% (w/w), respectively, as filter materials in the subsurface...
March 13, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/28289859/diagnosis-of-swallowing-disorders-how-we-interpret-pharyngeal-manometry
#17
REVIEW
Charles Cock, Taher Omari
PURPOSE OF REVIEW: We provide an overview of the clinical application of novel pharyngeal high-resolution impedance manometry (HRIM) with pressure flow analysis (PFA) in our hands with example cases. RECENT FINDINGS: In our Centre, we base our interpretation of HRIM recordings upon a qualitative assessment of pressure-impedance waveforms during individual swallows, as well as a quantitative assessment of averaged PFA swallow function variables. We provide a description of two global swallowing efficacy measures, the swallow risk index (SRI), reflecting global swallowing dysfunction (higher SRI = greater aspiration risk) and the post-swallow impedance ratio (PSIR) detecting significant post-swallow bolus residue...
March 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28289520/use-of-thyroglobulin-as-a-tumour-marker
#18
REVIEW
Buddhike Sri Harsha Indrasena
It is worthwhile to measure serum thyroglobulin (TG) level in thyroid cancer before subjecting patients to surgery for two reasons. Firstly, if the level is high, it may give a clue to the local and metastatic tumour burden at presentation; secondly, if the level is normal, it identifies the patients who are unlikely to show rising TG levels in the presence of thyroid cancer. Those who have high serum TG before surgery will show up recurrence as rising serum TG during the postoperative period. Those who do not have high serum TG before surgery will not show up rising serum TG in the presence of recurrent disease...
February 26, 2017: World Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28289429/hematological-and-plasma-biochemical-parameters-in-a-wild-population-of-naja-naja-linnaeus-1758-in-sri-lanka
#19
Duminda S B Dissanayake, Lasanthika D Thewarage, Rathnayake M P Manel Rathnayake, Senanayake A M Kularatne, Jamburagoda G Shirani Ranasinghe, Rajapakse P V Jayantha Rajapakse
BACKGROUND: Hematological studies of any animal species comprise an important diagnostic method in veterinary medicine and an essential tool for the conservation of species. In Sri Lanka, this essential technique has been ignored in studies of many species including reptiles. The aim of the present work was to establish a reference range of hematological values and morphological characterization of wild spectacled cobras (Naja naja) in Sri Lanka in order to provide a diagnostic tool in the assessment of health condition in reptiles and to diagnose diseases in wild populations...
2017: Journal of Venomous Animals and Toxins Including Tropical Diseases
https://www.readbyqxmd.com/read/28285499/clinico-epidemiological-patterns-of-cutaneous-leishmaniasis-patients-attending-the-anuradhapura-teaching-hospital-sri-lanka
#20
Lahiru Sandaruwan Galgamuwa, Buthsiri Sumanasena, Lalani Yatawara, Susiji Wickramasinghe, Devika Iddawela
Cutaneous leishmaniasis (CL) caused by Leishmania donovani is an endemic vector-borne disease in Sri Lanka. Over 2,500 cases have been reported since 2000 and the number of CL cases has dramatically increased annually. Total 57 clinically suspected CL patients attending the dermatology clinic in Anuradhapura Teaching Hospital were recruited from January to June 2015. Slit skin smears and skin biopsies were taken from each of the subjects. Clinical and epidemiological data were obtained using interviewer administered questionnaire...
February 2017: Korean Journal of Parasitology
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