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https://www.readbyqxmd.com/read/28812835/impact-of-health-research-systems-on-under-5-mortality-rate-a-trend-analysis
#1
Bahareh Yazdizadeh, Mahboubeh Parsaeian, Reza Majdzadeh, Sima Nikooee
BACKGROUND: Between 1990 and 2015, under-5 mortality rate (U5MR) declined by 53%, from an estimated rate of 91 deaths per 1000 live births to 43, globally. The aim of this study was to determine the share of health research systems in this decrease alongside other influential factors. METHODS: We used random effect regression models including the 'random intercept' and 'random intercept and random slope' models to analyze the panel data from 1990 to 2010. We selected the countries with U5MRs falling between the first and third quartiles in 1990...
November 26, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28810665/determinants-of-full-vaccination-status-in-children-aged-12-23-months-in-gur%C3%A3-%C3%A3-and-milange-districts-mozambique-results-of-a-population-based-cross-sectional-survey
#2
Shellese A Shemwell, Meridith B Peratikos, Lázaro González-Calvo, Montse Renom-Llonch, Alexandre Boon, Samuel Martinho, Charlotte B Cherry, Ann F Green, Troy D Moon
Background: In 2011, 64% of children in Mozambique, ages 12-23 months, were fully immunized. Large provincial differences in vaccine uptake exist. Methods: We conducted a survey of 1650 females with children aged 12-23 months in the districts of Gurùé and Milange. Implementation occurred from November to December 2014. Descriptive statistics and logistic regression using R-software 3.0.2 were used to examine factors associated with full vaccination status. ArcGIS version 10...
July 1, 2017: International Health
https://www.readbyqxmd.com/read/28808938/advances-in-vaccines-to-prevent-viral-respiratory-illnesses-in-children
#3
Aleisha J Anderson, Tom L Snelling, Hannah C Moore, Christopher C Blyth
Childhood vaccination has played a critical role in the reduction of morbidity and mortality from communicable diseases, including specific respiratory pathogens. Acute lower respiratory infection (ALRI) of both bacterial and viral aetiology continues to impact global child health. Key bacterial pathogens including Streptococcus pneumoniae and Haemophilus influenza type b are specifically targeted with current vaccination programmes, while at present there are less effective strategies for the prevention of viral disease...
August 14, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28805672/challenges-in-estimating-vaccine-coverage-in-refugee-and-displaced-populations-results-from-household-surveys-in-jordan-and-lebanon
#4
Timothy Roberton, William Weiss, Shannon Doocy
Ensuring the sustained immunization of displaced persons is a key objective in humanitarian emergencies. Typically, humanitarian actors measure coverage of single vaccines following an immunization campaign; few measure routine coverage of all vaccines. We undertook household surveys of Syrian refugees in Jordan and Lebanon, outside of camps, using a mix of random and respondent-driven sampling, to measure coverage of all vaccinations included in the host country's vaccine schedule. We analyzed the results with a critical eye to data limitations and implications for similar studies...
August 12, 2017: Vaccines
https://www.readbyqxmd.com/read/28803554/wealth-based-inequality-in-child-immunization-in-india-a-decomposition-approach
#5
Avijit Debnath, Nairita Bhattacharjee
Despite years of health and medical advancement, children still suffer from infectious diseases that are vaccine preventable. India reacted in 1978 by launching the Expanded Programme on Immunization in an attempt to reduce the incidence of vaccine-preventable diseases (VPDs). Although the nation has made remarkable progress over the years, there is significant variation in immunization coverage across different socioeconomic strata. This study attempted to identify the determinants of wealth-based inequality in child immunization using a new, modified method...
August 14, 2017: Journal of Biosocial Science
https://www.readbyqxmd.com/read/28801224/celiac-disease-and-increased-risk-of-pneumococcal-infection-a-systematic-review-and-meta-analysis
#6
Malorie Simons, Lori A J Scott-Sheldon, Yesenia Risech-Neyman, Steven Moss, Jonas F Ludvigsson, Peter Hr Green
BACKGROUND: Celiac disease has been associated with hyposplenism and multiple case reports link Celiac disease and pneumococcal infections; however, increased risk of pneumococcal infection in celiac disease has not been confirmed. The purpose of this study was to conduct a systematic review to determine the risk of pneumococcal infections in celiac disease. METHODS: Relevant studies were identified using electronic bibliographic searches of PubMed, OVID Medline and EMBASE (1980 to February 2017) and reviewing abstracts from major conferences in gastroenterology...
August 8, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28800730/genotypes-of-hepatitis-a-virus-in-turkey-first-report-and-clinical-profile-of-children-infected-with-sub-genotypes-ia-and-iiia
#7
Huseyin Yilmaz, Asiye Karakullukcu, Nuri Turan, Utku Y Cizmecigil, Aysun Yilmaz, Ayse A Ozkul, Ozge Aydin, Alper Gunduz, Mahmut Mete, Fadile Y Zeyrek, Taner T Kirazoglu, Juergen A Richt, Bekir Kocazeybek
BACKGROUND: Hepatitis A virus (HAV) is a food and water-borne virus causing clinical (mainly hepatitis) and subclinical disease in humans. It is important to characterize circulating strains of HAV in order to prevent HAV infections using efficacious vaccines. The aim of this study was the detection and characterization of the circulating strains of HAV in Turkey by performing serology, RT-PCR, sequencing and phylogenetic analysis. METHODS: In this study, 355 HAV suspected cases were analysed by ELISA for the presence of antibodies to HAV...
August 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28797115/ranking-93-health-interventions-for-low-and-middle-income-countries-by-cost-effectiveness
#8
Susan Horton, Hellen Gelband, Dean Jamison, Carol Levin, Rachel Nugent, David Watkins
BACKGROUND: Cost-effectiveness rankings of health interventions are useful inputs for national healthcare planning and budgeting. Previous comprehensive rankings for low- and middle- income countries were undertaken in 2005 and 2006, accompanying the development of strategies for the Millennium Development Goals. We update the rankings using studies published since 2000, as strategies are being considered for the Sustainable Development Goals. METHODS: Expert systematic searches of the literature were undertaken for a broad range of health interventions...
2017: PloS One
https://www.readbyqxmd.com/read/28795455/perceptions-of-caregivers-and-providers-regarding-the-potential-introduction-of-the-varicella-vaccine-to-the-childhood-immunisation-schedule-in-new-zealand-a-qualitative-exploratory-study
#9
Nadia A Charania, Donna G Watson, Nikki M Turner
AIM: The varicella vaccine has been proposed to be added to the childhood immunisation schedule in New Zealand as the fourth injectable at the 15-month event. We sought to understand the perceptions of caregivers and health-care providers regarding the potential introduction of routine varicella vaccination. METHODS: A qualitative exploratory study was conducted using semi-structured interviews with caregivers and providers (N = 20) in Auckland. Key themes from the interviews were identified through thematic analysis using a combination of deductive and inductive coding...
August 9, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28792852/squaring-state-child-vaccine-policy-with-individual-rights-under-the-individuals-with-disabilities-education-act-questions-raised-in-california
#10
Ross D Silverman, Wendy F Hensel
No abstract text is available yet for this article.
January 1, 2017: Public Health Reports
https://www.readbyqxmd.com/read/28774498/vaccine-hesitancy-where-we-are-and-where-we-are-going
#11
REVIEW
Catherine C McClure, Jessica R Cataldi, Sean T O'Leary
PURPOSE: Vaccines represent one of the most important aspects of pediatric preventive care. However, parents are increasingly questioning the safety of and need for vaccines, and as a result, vaccination rates have fallen to dangerously low levels in certain communities. The effects of vaccine hesitancy are widespread. Community pediatricians who interact regularly with vaccine-hesitant parents report higher levels of burnout and lower levels of job satisfaction. Not surprisingly, vaccine hesitancy has also had direct influence on vaccination rates, which in turn are linked to increased emergency department use, morbidity, and mortality...
July 31, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28770187/t-cell-lymphopenia-detected-by-newborn-screening-in-two-siblings-with-an-xq13-1-duplication
#12
Xavier Rios, Ivan K Chinn, Jordan S Orange, Celine I Hanson, Nicholas L Rider
Newborn screening for severe combined immunodeficiency has proven successful in identifying infants with T-cell deficiencies before they become severely ill. Additionally, the newborn screen can detect subtle early phenotypes that may become severe later in life. We present the case of siblings with features suggestive of T-cell lymphopenia identified as having low T-cell receptor excision circles counts by newborn screening. Expanded immune testing showed robust lymphocyte mitogen and antigen responses with normal vaccine responses and immunoglobulin levels for both boys over time...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28763922/-analysis-on-death-from-adverse-event-following-immunization-surveillance-system-of-shandong-province-during-2011-2016
#13
Y J Zhang
Objective: To analyze the occurrence and death of Adverse Event Following Immunization (AEFI) in Shandong province. Methods: Collecting the information of AEFI cases from 2011 to 2016, which were reported through the National AEFI Management System in Shandong province up to January 15, 2017. The autopsy reports of death following immunization were issued by the qualified institutions. The inoculation data from 2011 to 2016 was obtained through Immunization Information Management System of Shandong province...
August 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28759772/maternal-hiv-infection-associated-with-reduced-transplacental-transfer-of-measles-antibodies-and-increased-susceptibility-to-disease
#14
Sabelle Jallow, Clare L Cutland, Alexis K Masbou, Peter Adrian, Shabir A Madhi
BACKGROUND: Transplacental transfer of measles antibodies from mother to fetus is important in protecting against measles during early infancy. Changes in population immunity against measles in adults, including waning of immunity among HIV-infected pregnant women, could affect passive immunity acquired in utero by newborns. OBJECTIVES: To evaluate the effect of maternal HIV infection on transplacental transfer of measles antibody in mother-newborn dyads in a setting of high maternal HIV prevalence...
July 20, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28759395/childhood-illness-and-the-gender-gap-in-adolescent-education-in-low-and-middle-income-countries
#15
Marcella Alsan, Anlu Xing, Paul Wise, Gary L Darmstadt, Eran Bendavid
BACKGROUND: Achieving gender equality in education is an important development goal. We tested the hypothesis that the gender gap in adolescent education is accentuated by illnesses among young children in the household. METHODS: Using Demographic and Health Surveys on 41 821 households in 38 low- and middle-income countries, we used linear regression to estimate the difference in the probability adolescent girls and boys were in school, and how this gap responded to illness episodes among children <5 years old...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28757895/factors-influencing-mothers-decision-to-enroll-their-hiv-negative-children-in-a-hypothetical-hiv-vaccine-trial
#16
Victoria Williamson, Bronwyne Coetzee, Ashraf Kagee, Mark Tomlinson
Despite advances in preventive treatments for HIV, children continue to become infected with HIV. Research has investigated adult and adolescents' willingness to participate in hypothetical HIV vaccine trials; however, maternal willingness to enroll their infants in such trials remains underexplored. AIM: This study explored the factors influencing mothers' decision-making about enrolling their HIV negative infants in a hypothetical HIV vaccine trial. Methods: HIV infected and uninfected mothers (n = 22) were interviewed...
January 2017: Future Virology
https://www.readbyqxmd.com/read/28757060/mmr-and-mmrv-vaccines
#17
Frank Kowalzik, Jörg Faber, Markus Knuf
Measles, mumps, rubella and varicella are viral infections which can implicate seriously long-term sequelae of infected individuals or even the unborn child. Vaccines against the individual diseases have long been available. Global measles vaccination is estimated to have prevented more than 20million deaths during 2000-2015. During the same time period, measles incidence decreased from 146 to 36 cases per million populations. Today vaccinations against measles, mumps, rubella and varicella are now carried out mainly with combination vaccines...
July 27, 2017: Vaccine
https://www.readbyqxmd.com/read/28755045/influences-on-immunization-decision-making-among-us-parents-of-young-children
#18
Yunmi Chung, Jay Schamel, Allison Fisher, Paula M Frew
Objectives This study assessed influences on vaccination decisions among parents of young children and examined common vaccination information and advice sources. Methods Using panel samples of parents of children under 7 years, web-based surveys were conducted in 2012 (n = 2603) and 2014 (n = 2518). A vaccine decision-making typology (non-hesitant acceptors, hesitant acceptors, delayers, and refusers) was established and weighted population estimates of potential factors influencing parental vaccination decision (e...
July 28, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28754504/provider-communication-and-mothers-willingness-to-vaccinate-against-hpv-and-influenza-a-randomized-health-messaging-trial
#19
Kelly Donahue, Kristin Hendrix, Lynne Sturm, Gregory Zimet
OBJECTIVE: Understand the effect of a health messaging intervention focused on provider communication about vaccination on mothers' willingness to vaccinate children against HPV and seasonal influenza. METHODS: 2,476 mothers of 9-13-year-olds in the U.S. completed a Web-based survey in August 2014. Mothers were randomized to one of two groups targeting HPV or influenza vaccine. Mothers whose child had not received the target vaccine (i.e., zero doses of HPV vaccine/no prior-year administration of influenza vaccine) were randomized to the intervention...
July 25, 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/28750068/using-actor-partner-interdependence-modeling-to-understand-hpv-vaccine-acceptance
#20
Laura E VanderDrift, Peter A Vanable, Katherine E Bonafide, Jennifer L Brown, Rebecca A Bostwick, Michael P Carey
A wealth of scientific literature has been devoted to understanding what factors influence parents and their adolescent children to obtain the HPV vaccine. This literature is relatively uniform in its methodological approach of sampling individuals (i.e., either parents or adolescents) and examining the predictors of uptake for that individual. To improve understanding of HPV vaccination uptake, we sampled low-income, African American parent-child dyads with either a female (n = 93) or a male (n = 116) adolescent who had not been vaccinated...
2017: PloS One
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