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https://www.readbyqxmd.com/read/28935971/prevalence-of-chronic-hepatitis-b-and-status-of-hbv-care-among-rural-women-who-planned-to-conceive-in-china
#1
Yuanyuan Wang, Hong Zhou, Long Zhang, Qiuyue Zhong, Qiaomei Wang, Haiping Shen, Man Zhang, Yanjie Huang, Anqi Wang, Kenrad Nelson, Yiping Zhang, Donghai Yan, Zuoqi Peng, Ya Zhang, Xiaona Xin, Hongguang Zhang, Jun Zhao, Yan Wang, Ying Yang, Yuan He, Jihong Xu, Xiaoli Liu, Yan Wang, Xu Ma
Globally, one third of prevalent chronic hepatitis B (CHB) virus infection (HBV) occurred in China. Assessing the prevalence of CHB infesction and status of HBV-related services among pre-conception women will provide insight into risks of mother to child transmission (MTCT). A cross-sectional analysis of data from the National Free Pre-pregnancy Checkups (NFPC) program in 2010-2014 was conducted. A standardized questionnaire which collected demographic information and enzyme-linked immunosorbent assays (ELISA) which tested serological HBV markers were applied...
September 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28930165/timeliness-of-childhood-primary-immunization-and-risk-factors-related-with-delays-evidence-from-the-2014-zhejiang-provincial-vaccination-coverage-survey
#2
Yu Hu, Qian Li, Yaping Chen
Background: this study aimed to assess both immunization coverage and timeliness, as well as reasons for non-vaccination, and identity the risk factors of delayed immunization, for the vaccines scheduled during the first year of life, in Zhejiang province, east China. Methods: A cluster survey among children aged 24-35 months was conducted. Demographic information and socio-economic characteristics of the selected child, the mother, and the household were collected. Immunization data were transcribed from immunization cards...
September 20, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28928750/the-role-of-maternal-hiv-envelope-specific-antibodies-and-mother-to-child-transmission-risk
#3
REVIEW
Ayooluwa O Douglas, David R Martinez, Sallie R Permar
Despite the wide availability of antiretroviral therapy (ART) prophylaxis during pregnancy, >150,000 infants become infected through mother-to-child transmission (MTCT) of HIV worldwide. It is likely that additional intervention strategies, such as a maternal HIV vaccine, will be required to eliminate pediatric HIV infections. A deeper understanding of the fine specificity and function of maternal HIV envelope (Env)-specific responses that provide partial protection against MTCT will be critical to inform the design of immunologic strategies to curb the pediatric HIV epidemic...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28925418/mhealth-application-areas-and-technology-combinations-a-comparison-of-literature-from-high-and-low-middle-income-countries
#4
Haitham Abaza, Michael Marschollek
BACKGROUND: With the continuous and enormous spread of mobile technologies, mHealth has evolved as a new subfield of eHealth. While eHealth is broadly focused on information and communication technologies, mHealth seeks to explore more into mobile devices and wireless communication. Since mobile phone penetration has exceeded other infrastructure in low and middle-income countries (LMICs), mHealth is seen as a promising component to provide pervasive and patient-centered care. OBJECTIVES: The aim of our research work for this paper is to examine the mHealth literature to identify application areas, target diseases, and mHealth service and technology types that are most appropriate for LMICs...
August 8, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28924276/frequency-and-determinants-of-malnutrition-in-children-aged-between-6-to-59-months-in-district-tharparkar-a-rural-area-of-sindh
#5
Shahid Ahsan, Naveed Mansoori, Syed Maqsood Mohiuddin, Syed Muhammad Mubeen, Rubab Saleem, Muhammad Irfanullah
OBJECTIVE: To assess the nutritional status of children living in Tharparkar. METHODS: This cross-sectional study was conducted in four villages of Tharparkar district of Sindh, Pakistan, in 2014, and comprised children aged between 6 and 59 months. Data was collected from mothers and anthropometry of children was done using standard techniques. Nutritional status was assessed by using age- and sex-specific World Health Organisation standard charts for underweight, stunting and wasting...
September 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28915813/the-relationship-between-burden-of-childhood-disease-and-foreign-aid-for-child-health
#6
J Clay Bavinger, Paul Wise, Eran Bendavid
BACKGROUND: We sought to examine the relationship between child specific health aid (CHA) and burden of disease. Based on existing evidence, we hypothesized that foreign aid for child health would not be proportional to burden of disease. METHODS: In order to examine CHA and burden of disease, we obtained estimates of these parameters from established sources. Estimates of disability adjusted life years (DALYs) in children (0-5 years) were obtained from the World Health Organization for 2000 and 2012...
September 15, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28898512/knowledge-attitudes-and-opinions-towards-measles-and-the-mmr-vaccine-across-two-nsw-cohorts
#7
Daniel Brieger, Matthew Edwards, Poonam Mudgil, John Whitehall
OBJECTIVE: Although the number of national measles cases has greatly decreased since 1980s, there has been resurgence in disease incidence in recent years. While parental knowledge and attitudes toward both disease and vaccinations are known to influence vaccine uptake, the contribution of these factors toward vaccination rates in NSW populations has not been studied. The aim of this study was to investigate the knowledge and opinions on measles and MMR vaccine in NSW Central and North Coast regions...
September 12, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28893935/tumour-virus-vaccines-hepatitis-b-virus-and-human-papillomavirus
#8
REVIEW
Margaret Stanley
Two of the most important human oncogenic viruses are hepatitis B virus (HBV) and human papillomavirus (HPV). HBV infection has been preventable by vaccination since 1982; vaccination of neonates and infants is highly effective, resulting already in decreased rates of new infections, chronic liver disease and hepato-cellular carcinoma. Nonetheless, HBV remains a global public health problem with high rates of vertical transmission from mother to child in some regions. Prophylactic HPV vaccines composed of virus-like particles (VLPs) of the L1 capsid protein have been licensed since 2006/2007...
October 19, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28893479/reaching-every-child-with-rotavirus-vaccine-report-from-the-10th-african-rotavirus-symposium-held-in-bamako-mali
#9
Samba O Sow, A Duncan Steele, Jason M Mwenda, George E Armah, Kathleen M Neuzil
The Center for Vaccine Development - Mali (CVD - Mali), the World Health Organization's regional office in Africa (WHO/AFRO), and the CVD at the University of Maryland School of Medicine hosted the 10th African Rotavirus Symposium in Bamako, Mali on 1-2 June 2016. The symposium is coordinated by WHO/AFRO, the Regional Rotavirus Reference Laboratories, and the African Rotavirus Network (ARN), with support from the Bill & Melinda Gates Foundation. The event brings together leading rotavirus researchers, scientists, and policy-makers from across Africa and the world...
September 8, 2017: Vaccine
https://www.readbyqxmd.com/read/28893475/impact-of-five-years-of-rotavirus-vaccination-in-finland-and-the-associated-cost-savings-in-secondary-healthcare
#10
Tuija Leino, Ulrike Baum, Peter Scott, Jukka Ollgren, Heini Salo
INTRODUCTION: This study aimed to estimate the impact of the national rotavirus (RV) vaccination programme, starting 2009, on the total hospital-treated acute gastroenteritis (AGE) and severe RV disease burden in Finland during the first five years of the programme. This study also evaluated the costs saved in secondary healthcare by the RV vaccination programme. METHODS: The RV related outcome definitions were based on ICD10 diagnostic codes recorded in the Care Register for Health Care...
September 8, 2017: Vaccine
https://www.readbyqxmd.com/read/28893474/assessing-care-givers-satisfaction-with-child-immunisation-services-in-zambia-evidence-from-a-national-survey
#11
Chitalu Miriam Chama-Chiliba, Felix Masiye, Chrispin Mphuka
AIM: The main aim of this study was to assess care-giver satisfaction with vaccination services in public health facilities in Zambia, and examine its determinants. METHODS: This study used data from a recent population-based household survey, conducted from May to August 2015. Respondent satisfaction with vaccination services received during the last visit was measured on a five point Likert scale ranging from 1 to 5. We used an ordered logistic regression model to analyse the significance of perceived quality of vaccination services, immunisation delivery mode and a range of individual characteristics in predicting care-giver satisfaction...
September 8, 2017: Vaccine
https://www.readbyqxmd.com/read/28892455/modeling-specific-antibody-responses-to-natural-immunization-to-predict-a-correlate-of-protection-against-infection-before-commencing-a-clinical-vaccine-trial
#12
Anthony Almudevar, Michael E Pichichero
i) Background: Clinical trials of vaccines for children to prevent acute otitis media (AOM) infections caused by the bacteria Streptococcus pneumonia (Spn) are in Phase I. The objective of this study was to use serum antibody measurements to pneumococcal purified protein candidate antigens that occurred after natural "immunization" to predict a correlate of protection response needed following an injectable vaccine against AOM in children. METHODS: 590 nasal and serum samples were collected from 129 healthy children at 6, 9, 12, 15, 18, 24 and 30-36 months of age and when the child developed AOM...
September 11, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28891541/inequity-in-access-to-childhood-immunization-in-enugu-urban-southeast-nigeria
#13
B S Uzochukwu, C C Okeke, E Envuladu, C Mbachu, C Okwuosa, O E Onwujekwe
BACKGROUND: The Nigerian National Programme on Immunization aims at increasing the immunization coverage of children under 1 year of age. However, there is still a gap between the national immunization targets and the immunization coverage rates, and data are rarely disaggregated according to socioeconomic status. As a result, there is a dearth of information about the coverage of subgroups, especially at the local level. This study determined the socioeconomic differentials in immunization coverage for children under 5 years and under 1 year in Enugu urban, Southeast Nigeria...
August 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28884450/illness-representations-of-pertussis-and-predictors-of-child-vaccination-among-mothers-in-a-strict-vaccination-exemption-state
#14
Rahul Garg, Abdulkarim Meraya, Pamela J Murray, Kimberly Kelly
Background Vaccine preventable diseases are making a comeback in the US. However, research is lacking on illness representations of vaccine preventable diseases and their application in improving childhood immunization. Objective We utilized the common sense model of self-regulation to examine illness representations of pertussis and their associations with child's receipt of any vaccine, up-to-date vaccination status, and mothers' intentions to follow the recommended vaccination schedule in the future. Methods We developed vaccine worry and vaccine hassles scales to assess mothers' worries and hassles for child vaccination, and used an open ended question to assess mother's illness representations of pertussis...
September 7, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28883971/vaccination-of-hiv-infected-pregnant-women-implications-for-protection-of-their-young-infants
#15
REVIEW
Ziyaad Dangor, Marta C Nunes, Gaurav Kwatra, Sanjay G Lala, Shabir A Madhi
BACKGROUND: The prevention of mother to child transmission of HIV has resulted in reduced burden of pediatric HIV-infection, but the prevalence of maternal HIV infection remains high in sub-Saharan African countries. HIV-exposed-uninfected infants have an increased risk of morbidity and mortality due to infectious diseases than HIV-unexposed infants, particularly during the first six months of life, which in part might be due to lower levels of pathogen-specific protective antibodies acquired transplacentally from their mothers...
2017: Tropical Diseases, Travel Medicine and Vaccines
https://www.readbyqxmd.com/read/28882091/measles-lymphadenopathy-in-a-child-with-pfapa-syndrome
#16
Jefferson Terry, Kelly Brown, Joanne Hiebert, Ghada N Al-Rawahi, J Paul Moxham, Mel Krajden, Agatha N Jassem, Lori Tucker
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is a common cause of periodic fever in children. The pathogenesis of PFAPA is unknown but likely involves immune system dysregulation and may be initiated by an environmental trigger. Tonsillectomy resolves or improves symptoms in some patients, but the reason for this is unknown; moreover, specific abnormalities in tonsillectomy specimens from PFAPA patients have not been described. Here, we report measles virus in tonsil from a child with PFAPA...
January 1, 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28872773/exploring-provider-and-parental-perceptions-to-influenza-vaccination-in-the-inpatient-setting
#17
Suchitra Rao, Victoria Fischman, Angela Moss, Sonja I Ziniel, Michelle R Torok, Heidi McNeely, Daniel Hyman, Karen M Wilson, Amanda F Dempsey
BACKGROUND: Hospitalization provides an ideal opportunity for immunization, but few studies have explored provider and parental attitudes towards pediatric inpatient vaccination against influenza. OBJECTIVES: The objectives were to determine provider and caregiver attitudes and explore potential barriers to inpatient influenza vaccination. METHODS: We developed and distributed two surveys to parents/caregivers as well as providers of general pediatric inpatients at Children's Hospital Colorado between October 2014 and March 2015 assessing attitudes towards influenza and inpatient influenza vaccination...
September 5, 2017: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/28870397/eradicating-hepatitis-b-virus-the-critical-role-of-preventing-perinatal-transmission
#18
REVIEW
Cladd E Stevens, Pearl Toy, Saleem Kamili, Patricia E Taylor, Myron J Tong, Guo-Liang Xia, Girish N Vyas
Prevention of hepatitis B virus (HBV) transmission from infected mothers to their newborns is critical to HBV control and eventual eradication. Mother-to-child perinatal transmission causes the highest chronic carrier rate (>85%) with a high rate of subsequent chronic liver disease and hepatocellular carcinoma. This risk is reduced by 90% with HBV vaccine given along with hepatitis B immune globulin (HBIG) starting at birth. New analyses of our data from US trials of HBIG and HBV vaccine in high-risk infants revealed better efficacy with yeast-recombinant vaccine than plasma-derived vaccine, especially in preventing late onset infections, with evidence that vaccine prevented transmission of maternal HBV infection with the glycine to arginine mutation in surface antigen codon 145 (sG145R)...
September 1, 2017: Biologicals: Journal of the International Association of Biological Standardization
https://www.readbyqxmd.com/read/28866291/a-single-dose-and-long-lasting-vaccine-against-pandemic-influenza-through-the-controlled-release-of-a-heterospecies-tandem-m2-sequence-embedded-within-detoxified-bacterial-outer-membrane-vesicles
#19
Hannah C Watkins, Catalina L Pagan, Hannah R Childs, Sara Posada, Annie Chau, Jose Rios, Cassandra Guarino, Matthew P DeLisa, Gary R Whittaker, David Putnam
The influenza A virus undergoes genetic drift and shift, leaving the general population susceptible to emerging pandemic strains, despite seasonal flu vaccination. Here we describe a single dose influenza vaccine derived from recombinant outer membrane vesicles (rOMVs) that display an antigen-mapped heterospecies tandem sequence of the M2 protein from the influenza A virus, released over 30days from poly(lactic-co-glycolide) (PLGA) microparticles. Four weeks post vaccination, BALB/c mice developed high anti-M2e IgG titers that were equivalent to those generated at 8weeks in a typical prime/boost vaccine regimen...
September 25, 2017: Vaccine
https://www.readbyqxmd.com/read/28866290/immunogenicity-safety-and-reactogenicity-of-the-pneumococcal-non-typeable-haemophilus-influenzae-protein-d-conjugate-vaccine-phid-cv-in-2-17-year-old-children-with-asplenia-or-splenic-dysfunction-a-phase-3-study
#20
L Szenborn, I V Osipova, H Czajka, S M Kharit, T Jackowska, N François, M A Habib, D Borys
BACKGROUND: Immunization with pneumococcal vaccines is an important prophylactic strategy for children with asplenia or splenic dysfunction, who are at high risk of bacterial infections (including S. pneumoniae). This study aimed to assess immunogenicity and safety of pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV, GSK) in this at-risk population. METHODS: This phase III, multi-centre, open-label, controlled study, in which at-risk children with asplenia or splenic dysfunction were enrolled (age strata: 2-4, 5-10 and 11-17years), was conducted in Poland and the Russian Federation...
September 25, 2017: Vaccine
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