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https://www.readbyqxmd.com/read/28526006/cardiometabolic-profile-of-obese-children-in-a-sub-saharan-african-setting-a-cross-sectional-study
#1
Eunice Chedjou-Nono, Suzanne Sap, Simeon-Pierre Choukem, Issa Ngosso Tetanye, Daniel Nebongo, Olivier Koki Ndombo
BACKGROUND: Cardiovascular and metabolic consequences of obesity in children, unlike adults, are still not well understood nor have they been subject to extensive research in Africa. We aimed to identify the cardio-metabolic complications associated with childhood obesity at the early phase of the management of obese children in a reference center in Cameroon. METHODS: In this cross-sectional study conducted from November 2013 to September 2014 and based on World Health Organization (WHO) classification of Obesity (BMI > 3SD under 5 years and BMI > 2SD from 5 and above), we included children aged 3 to 17 years who were being followed up for obesity at the pediatric endocrinology unit of the Mother and Child Center of the Chantal BIYA Foundation in Yaounde, Cameroon...
May 19, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28521627/disseminated-bacillus-calmette-gu%C3%A3-rin-osteomyelitis-in-twin-sisters-related-to-stat1-gene-deficiency
#2
Sabah Boudjemaa, Linda Dainese, Sébastien Héritier, Caroline Masserot, Samia Hachemane, Jean-Laurent Casanova, Aurore Coulomb, Jacinta Bustamante
Mendelian susceptibility to mycobacterial disease is a rare syndrome characterized by severe clinical infections usually caused by weakly virulent mycobacterial species such as Bacillus Calmette-Guérin vaccines and environmental nontuberculous mycobacteria or more virulent mycobacteria as mycobacterium tuberculosis. Since 1996, 9 genes including 7 autosomal ( STAT1, IFNGR1, IFNGR2, IL12B, IL12RB1, ISG15, and IRF8) and 2 X-linked genes ( NEMO and CYBB) have been identified. Allelic heterogeneity leaded to recognize about 18 genetic diseases with variable clinical phenotypes, but sharing a same physiological mechanism represented by a defect in human IL-12-dependant-INF-γ-mediated immunity...
June 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28510997/impact-of-m-health-application-used-by-community-health-volunteers-on-improving-utilization-of-maternal-newborn-and-child-health-care-services-in-a-rural-area-of-uttar-pradesh-india
#3
Shankar Prinja, Ruby Nimesh, Aditi Gupta, Pankaj Bahuguna, Madhu Gupta, Jarnail Singh Thakur
OBJECTIVE: To raise the quality of counselling by community health volunteers resulting in improved uptake of maternal, neonatal and child health services (MNCH), an m-health application was introduced under a project named 'Reducing Maternal and Newborn Deaths (ReMiND)' in district Kaushambi in India. We report the impact of this project on coverage of key MNCH services. METHODS: A pre and post quasi-experimental design was undertaken to assess the impact of intervention...
May 16, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28509517/impact-of-providing-free-preventive-dental-products-without-health-workers-counselling-on-infants-tooth-brushing-and-bottle-feeding-termination-practices-a-randomised-controlled-trial
#4
E Joury, M Alghadban, K Elias, R Bedi
OBJECTIVE: To investigate the impact of an integrated oral health promotion intervention, within the Syrian national immunisation programme, which provided free preventive dental health products, without health workers' counselling, on one-year-old infants' tooth-brushing and bottle-feeding termination practices. RESEARCH DESIGN: a randomised controlled parallel-group trial. SETTING: A maternal and child health centre in Sweida city, Syria...
September 2016: Community Dental Health
https://www.readbyqxmd.com/read/28507351/practice-of-breastfeeding-and-immunisation-in-a-periurban-community-in-pakistan
#5
Haider Ghazanfar, Sualeha Saleem, Sajida Naseem, Ali Ghazanfar
OBJECTIVE: To assess the practice of breastfeeding and immunisation in a peri-urban community and correlate it with maternal care during pregnancy of the index child. METHODS: This community-based, cross-sectional survey was conducted at Shifa Tameer-e-Millat University and Shifa College of Medicine, Islamabad, Pakistan, from June 2014 to January 2016, using a self-generated questionnaire. Systemic random sampling method was used to collect data. SPSS 21 was used to analyse the data and to find associations between maternal care and practices of breastfeeding...
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28500809/investigating-mumps-outbreak-in-odisha-india-an-opportunity-to-assess-the-health-system-by-utilizing-the-essential-public-health-services-framework
#6
Sourabh Paul, Preetam B Mahajan, Jyotiranjan Sahoo, Vikas Bhatia, Sonu H Subba
AbstractMumps, a highly contagious, viral disease continues to spread in India, despite the availability of an effective vaccine. On November 24, 2014, we came across a suspected case of mumps in a 6-year-old boy in a village of Bhusandapur sector in Odisha. We initiated an outbreak investigation using standard techniques outlined by the Centers for Disease Control and Prevention, Atlanta, GA. This uncovered a silent epidemic of 94 case patients (10% of the population) over a period of 16 weeks between August and December 2014, in a single village, which had gone completely unnoticed by the existing health-care system...
May 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28495264/community-engagement-and-integrated-health-and-polio-immunisation-campaigns-in-conflict-affected-areas-of-pakistan-a-cluster-randomised-controlled-trial
#7
Muhammad Atif Habib, Sajid Soofi, Simon Cousens, Saeed Anwar, Najib Ul Haque, Imran Ahmed, Noshad Ali, Rehman Tahir, Zulfiqar A Bhutta
BACKGROUND: Pakistan faces huge challenges in eradicating polio due to widespread poliovirus transmission and security challenges. Innovative interventions are urgently needed to strengthen community buy-in, to increase the coverage of oral polio vaccine (OPV) and other routine immunisations, and to enhance immunity through the introduction of inactivated polio vaccine (IPV) in combination with OPV. We aimed to evaluate the acceptability and effect on immunisation coverage of an integrated strategy for community engagement and maternal and child health immunisation campaigns in insecure and conflict-affected polio-endemic districts of Pakistan...
June 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28488502/parents-may-not-want-children-vaccinated-against-influenza
#8
(no author information available yet)
Parents who generally support vaccination may doubt the necessity of an influenza vaccination for their child, research suggests.
May 10, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28483064/missed-opportunities-for-hepatitis-a-vaccination-national-immunization-survey-child-2013
#9
Shannon M Casillas, Robert A Bednarczyk
OBJECTIVES: To quantify the number of missed opportunities for vaccination with hepatitis A vaccine in children and assess the association of missed opportunities for hepatitis A vaccination with covariates of interest. STUDY DESIGN: Weighted data from the 2013 National Immunization Survey of US children aged 19-35 months were used. Analysis was restricted to children with provider-verified vaccination history (n = 13 460). Missed opportunities for vaccination were quantified by determining the number of medical visits a child made when another vaccine was administered during eligibility for hepatitis A vaccine, but hepatitis A vaccine was not administered...
May 5, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28482004/imputing-direct-and-indirect-vaccine-effectiveness-of-childhood-pneumococcal-conjugate-vaccine-against-invasive-disease-by-surveying-temporal-changes-in-nasopharyngeal-pneumococcal-colonization
#10
Susan A Nzenze, Shabir A Madhi, Tinevimbo Shiri, Keith P Klugman, Linda de Gouveia, David P Moore, Alan S Karstaedt, Stefano Tempia, Marta C Nunes, Anne von Gottberg
The limited capabilities in most low-middle income countries to study the bebfit of pneumococcal conjugate vaccine (PCV) against invasive pneumococcal disease (IPD), calls for alternate strategies to assess this. We used a mathematical model, to predict the direct and indirect effectiveness of PCV by analyzing serotype specific colonization prevalence and IPD incidence prior to and following childhood PCV immunization in South Africa. We analyzed IPD incidence from 2005-2012 and colonization studies undertaken in HIV-uninfected and HIV-infected child-mother dyads from 2007-2009 (pre-PCV era), in 2010 (7-valent PCV era) and 2012 (13-valent PCV era)...
May 6, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28475224/prevalence-and-characteristics-of-complementary-and-alternative-medicine-use-by-australian-children
#11
Jane E Frawley, Dennis Anheyer, Sandy Davidson, Debra Jackson
AIM: This study was conducted to evaluate the use of complementary and alternative medicine (CAM) among Australian children within the previous 12 months. METHODS: Parents with children up to the age of 18 years were recruited from online parenting groups. Questions addressed demographic factors, socio-economic status, conventional health service use, including vaccination status and use of CAM. RESULTS: A total of 149 parents responded to the study of which 73...
May 5, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28474585/introduction-of-new-vaccines-in-state-immunization-schedule-delhi-s-experience
#12
Amita Raoot, Dharmendra Kumar Dewan, A P Dubey, Suresh Seth
Immunization is an established, cost-effective, preventive intervention to improve child survival. To provide protection against vaccine preventable diseases, all countries in the world have an immunization program that offers selected vaccines to the eligible beneficiaries. In India, Expanded Program of Immunization was started in 1978, and then Universal Immunization Program was launched in 1985 with six antigens. This article describes the experience with institutionalization of four state-specific vaccines by Delhi in its immunization schedule to enlarge the ambit of immunization services...
April 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28474505/house-dust-mite-specific-immunotherapy-with-two-licensed-vaccines-outcome-under-clinical-routine-conditions
#13
Vera Mahler, Christian Klein, Angelika Sager, Jürgen Zimmermann
INTRODUCTION: House dust mite (HDM) allergens are major causes for the development of allergic diseases. A disease modifying effect and clinical benefit of allergen immunotherapy (AIT) has been demonstrated in a number of clinical trials. Clinical trials, however, are carried out in selected populations under specific conditions based on inclusion and exclusion criteria and may not represent the entire patient population from medical practice. Objective of this study conducted in patients with HDM allergy was to systematically collect information about the benefit of AIT under clinical routine conditions...
June 2017: Immunity, Inflammation and Disease
https://www.readbyqxmd.com/read/28474295/individual-preferences-for-child-and-adolescent-vaccine-attributes-a-systematic-review-of-the-stated-preference-literature
#14
REVIEW
Christine Michaels-Igbokwe, Shannon MacDonald, Gillian R Currie
BACKGROUND: Discrete choice experiments are increasingly used to assess preferences for vaccines and vaccine service delivery. OBJECTIVES: To synthesize and critically assess the application of discrete choice experiments in childhood/adolescent vaccines, to describe how discrete choice experiments have been applied to understand preferences, and to evaluate the use of discrete choice experiment data to inform estimates of vaccine uptake. METHODS: We conducted a systematic review of six electronic databases...
May 4, 2017: Patient
https://www.readbyqxmd.com/read/28473508/uk-parents-attitudes-towards-meningococcal-group-b-menb-vaccination-a-qualitative-analysis
#15
Cath Jackson, Joanne Yarwood, Vanessa Saliba, Helen Bedford
OBJECTIVES: (1) To explore existing knowledge of, and attitudes, to group B meningococcal disease and serogroup B meningococcal (MenB) vaccine among parents of young children. (2) To seek views on their information needs. DESIGN: Cross-sectional qualitative study using individual and group interviews conducted in February and March 2015, prior to the introduction of MenB vaccine (Bexsero) into the UK childhood immunisation schedule. SETTING: Community centres, mother and toddler groups, parents' homes and workplaces in London and Yorkshire...
May 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28470110/growth-pattern-in-ethiopian-infants-the-impact-of-exposure-to-maternal-hiv-infection-in-relation-to-socio-economic-factors
#16
John König Walles, Taye Tolera Balcha, Niclas Winqvist, Per Björkman
BACKGROUND: Infants exposed to maternal HIV infection who remain HIV-uninfected (HIV-exposed/uninfected; HIV-EU) may be at increased risk of growth retardation, which could be due both to directly HIV-related effects and to socio-economic factors overrepresented among HIV-positive women. OBJECTIVE: To investigate growth development at 9-12 months of age in HIV-EU infants participating in prevention of mother-to-child transmission (PMTCT) care compared to HIV unexposed (HIV-U) infants in relation to socio-economic conditions...
2017: Global Health Action
https://www.readbyqxmd.com/read/28468062/-sero-epidemiological-analysis-on-hepatitis-b-among-children-aged-1-14-years-old-born-to-hbsag-positive-mother-in-china-2014
#17
F Z Wang, H Zheng, G M Zhang, N Miao, X J Sun, F Q Cui
Objective: To analyze the sero-epidemiological features of hepatitis B among children aged 1-14 years old who were born to HBsAg positive mothers. Methods: Based on the results from the hepatitis B national sero-survey in 2014, children aged 1-14 years old born to HBsAg positive mother were involved in this study. Positive rates on HBsAg, anti-HBs, anti-HBc by gender, age, nationality, birth place, residency (urban/rural), region (eastern/central/western) and related factors of HBsAg and anti-HBs for children under research, were analyzed by SPSS 18...
April 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28465839/prevalence-of-hepatitis-b-virus-infection-among-pregnant-women-attending-antenatal-clinics-in-vientiane-laos-2008-2014
#18
Marc Choisy, Sengdeuane Keomalaphet, Kinnaly Xaydalasouk, Fabrice Quet, Vatthanaphone Latthaphasavang, Yves Buisson
The Lao People's Democratic Republic (PDR) is still considered a highly endemic country for hepatitis B, mainly due to perinatal transmission of hepatitis B virus (HBV), despite efforts made since 2004 for universal immunization of newborns. The prevalence of HBV surface antigen (HBsAg) carriage in pregnant women is a relevant marker for the risk of mother-to-child HBV transmission. This study aimed to assess the changes in prevalence of HBV infection among pregnant women attending the Mahosot Prenatal Clinic (Vientiane Capital)...
2017: Hepatitis Research and Treatment
https://www.readbyqxmd.com/read/28464403/seasonal-variation-in-child-mortality-in-rural-guinea-bissau
#19
Bibi Uhre Nielsen, Stine Byberg, Peter Aaby, Amabelia Rodrigues, Christine Stabell Benn, Ane Baerent Fisker
OBJECTIVES: In many African countries, child mortality is higher in the rainy season than in the dry season. We investigated the effect of season on child mortality by time periods, sex, and age in rural Guinea-Bissau. METHODS: Bandim health project follows children under-five in a health and demographic surveillance system in rural Guinea-Bissau. We compared the mortality in the rainy season (June to November) between 1990 and 2013 with the mortality in the dry season (December to May) in Cox proportional hazards models providing rainy versus dry season mortality rate ratios (r/d-mrr)...
May 2, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28463942/diagnostic-practices-for-suspected-community-acquired-central-nervous-system-infection-in-the-post-conjugate-vaccine-era
#20
Natalie Banniettis, Saumya Joshi, Shubhi Kaushik, Stephan Kohlhoff, Margaret R Hammerschlag
OBJECTIVE: The aim of this study was to evaluate diagnostic practices for suspected community-acquired central nervous system (CNS) infection in an urban pediatric population. METHODS: This is an observational, retrospective single-center review of cerebrospinal fluid (CSF) studies in children, 1 month to 21 years old, evaluated for suspected CNS infection from 2004 to 2014. Cases of suspected nosocomial meningitis were excluded. The frequency of N-methyl-D-aspartate receptor antibody (NMDAR ab) encephalitis was analyzed from 2010 to 2014...
May 1, 2017: Pediatric Emergency Care
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