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https://www.readbyqxmd.com/read/29775037/recommendations-for-safe-vaccination-in-children-at-the-risk-of-taking-allergic-reactions-to-vaccine-components
#1
(no author information available yet)
Vaccines are one of the most important advances in medicine as a public health tool for the control of immunopreventable diseases. Occasionally, adverse reactions may occur. If a child has a reaction to a vaccine, it is likely to disrupt his immunization schedule with risks to himself and the community. This establishes the importance of correctly diagnosing a possible allergy and defining appropriate behavior. Allergic reactions to vaccines may be due to the immunogenic component, to the residual proteins in the manufacturing process and to antimicrobial agents, stabilizers, preservatives and any other element used in the manufacturing process...
April 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29773490/addressing-parents-vaccine-concerns-a-randomized-trial-of-a-social-media-intervention
#2
Matthew F Daley, Komal J Narwaney, Jo Ann Shoup, Nicole M Wagner, Jason M Glanz
INTRODUCTION: Successful strategies are needed to address parental vaccine hesitancy, a significant public health issue. The study objective was to assess whether an Internet-based platform with vaccine information and interactive social media components improved parents' vaccine-related attitudes. STUDY DESIGN: A three-arm RCT. SETTING/PARTICIPANTS: The study was conducted in a large Colorado integrated healthcare organization. Parents were enrolled during September 2013 through October 2015 and followed through November 2016; data were analyzed in 2017...
May 8, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29773279/-non-tuberculous-mycobacterial-cervical-adenitis-in-children-2-cases
#3
N Sigg, S Bailleul, J-M Turmel, G Legrand, S Kettani, L Martin
BACKGROUND: Cervical lymphadenitis is the most common manifestation of infection with nontuberculous mycobacteria (NTM) in immunocompetent children. Nevertheless, it is poorly known by dermatologists. Its incidence, which is currently increasing since the cessation of BCG vaccination in 2007, raises several issues regarding its pathophysiology, diagnosis and management. PATIENTS AND METHODS: We report two cases of NTM adenitis: one in a 2-year-old girl vaccinated with BCG and one in an unvaccinated 22-month-old boy, in whom a misleading presentation led to delayed diagnosis...
May 14, 2018: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29771633/a-path-analysis-model-suggesting-the-association-between-health-locus-of-control-and-compliance-with-childhood-vaccinations
#4
Anat Amit Aharon, Haim Nehama, Shmuel Rishpon, Orna Baron-Epel
Despite vaccines benefits, parent's vaccine hesitancy is growing. Health locus of control (HLOC) may affect decision making regarding child vaccinations. The aim of this study was to investigate the relationship between parents' HLOC and compliance with routine childhood immunization programs. A cross-sectional survey was conducted among 731 parents of children aged 3-4 years. Internal HLOC, powerful others and chance HLOC (dimensions of external HLOC), reliability of information sources, and attitudes towards vaccines were measured...
May 17, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29769807/immunization-of-the-immunocompromised-child-key-principles
#5
Dorothy L Moore
The immunization of immunocompromised children requires vaccination strategies that provide maximum protection with minimal harm. Responsibility for immunization is shared by their primary care providers and their specialists. Detailed guidelines are published in the current version of the Canadian Immunization Guide and general principles are outlined here.
May 2018: Paediatrics & Child Health
https://www.readbyqxmd.com/read/29769034/demand-side-determinants-of-timely-vaccination-of-oral-polio-vaccine-in-social-mobilization-network-areas-of-core-group-polio-project-in-uttar-pradesh-india
#6
Manojkumar Choudhary, Roma Solomon, Jitendra Awale, Rina Dey
BACKGROUND: Children who receive all doses of scheduled vaccines reduce their susceptibility to vaccine-preventable diseases. In India, full immunization coverage has increased significantly. However, only a small proportion of children are immunized on time. Globally, studies on factors affecting coverage of childhood immunization have found a significant impact by demand and supply-side determinants. This paper explores the demand-side determinants of timely immunization of the third dose of oral polio vaccine (OPV3) among children aged 6-11 months in the catchment areas of CORE Group Polio Project India...
May 16, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29765775/potential-impact-of-introducing-the-pneumococcal-conjugate-vaccine-into-national-immunisation-programmes-an-economic-epidemiological-analysis-using-data-from-india
#7
Itamar Megiddo, Eili Klein, Ramanan Laxminarayan
Pneumococcal pneumonia causes an estimated 105 000 child deaths in India annually. The planned introduction of the serotype-based pneumococcal conjugate vaccine (PCV) is expected to avert child deaths, but the high cost of PCV relative to current vaccines provided under the Universal Immunization Programme has been a concern. Cost-effectiveness studies from high-income countries are not readily comparable because of differences in the distribution of prevalent serotypes, population and health systems. We extended IndiaSim, our agent-based simulation model representative of the Indian population and health system, to model the dynamics of Streptococcus pneumoniae ...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29764679/association-between-provider-recommendation-and-influenza-vaccination-status-among-children
#8
Katherine E Kahn, Tammy A Santibanez, Yusheng Zhai, Carolyn B Bridges
BACKGROUND: Provider recommendation is associated with influenza vaccination receipt. The objectives of this study were to estimate the percentage of children 6 months-17 years for whom a provider recommendation for influenza vaccination was received, identify factors associated with receipt of provider recommendation, and evaluate the association between provider recommendation and influenza vaccination status among children. METHODS: National Immunization Survey-Flu (NIS-Flu) parentally reported data for the 2013-14, 2014-15, and 2015-16 seasons were analyzed...
May 12, 2018: Vaccine
https://www.readbyqxmd.com/read/29755930/parents-attitudes-towards-topical-fluoride-and-vaccines-for-children-are-these-distinct-or-overlapping-phenomena
#9
Richard M Carpiano, Donald L Chi
Despite attention paid to parental refusal of child vaccines, the phenomenon of topical fluoride refusal is poorly understood. We examine the extent to which parent attitudes and Internet use regarding topical fluoride treatment and vaccines may overlap and, in turn, uniquely or distinctly correlate with fluoride and vaccine refusal for the child. In 2017, we analyzed data collected from 2011 to 12 for 361 children from three Washington state dental clinics. The instrument included analogous measures of topical fluoride and vaccine safety concerns, perceived severity of preventable cavities/disease, and Internet use for fluoride/vaccine information; and measures of non-fluoridated toothpaste use, attitudes towards dental x-rays and amalgam and composite fillings...
June 2018: Preventive Medicine Reports
https://www.readbyqxmd.com/read/29755760/impact-of-measles-supplementary-immunisation-activities-on-utilisation-of-maternal-and-child-health-services-in-low-income-and-middle-income-countries
#10
Iryna Postolovska, Stéphane Helleringer, Margaret E Kruk, Stéphane Verguet
Background: Measles supplementary immunisation activities (SIAs) are an integral component of measles elimination in low-income and middle-income countries (LMICs). Despite their success in increasing vaccination coverage, there are concerns about their negative consequences on routine services. Few studies have conducted quantitative assessments of SIA impact on utilisation of health services. Methods: We analysed the impact of SIAs on utilisation of selected maternal and child health services using Demographic and Health Surveys and Multiple Indicator Cluster Surveys from 28 LMICs, where at least one SIA occurred over 2000-2014...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29752131/effectiveness-of-the-dtpa-hbv-ipv-hib-vaccine-against-invasive-haemophilus-influenzae-type-b-disease-in-the-netherlands-2003-16-a-case-control-study
#11
Susana Monge, Susan Jm Hahné, Hester E de Melker, Elisabeth Am Sanders, Arie van der Ende, Mirjam J Knol
BACKGROUND: In 2016, an increase in invasive Haemophilus influenzae serotype b (Hib) disease was reported in the Netherlands in children younger than 5 years, which coincided with the introduction of the hexavalent diphtheria, tetanus, and acellular pertussis-hepatitis B virus-inactivated polio virus/Hib vaccine (DTPa-HBV-IPV/Hib) from 2011 onwards. We aimed to estimate the effectiveness of the hexavalent vaccine to assess whether this increase could be explained by decreasing effectiveness...
May 8, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29752026/safety-of-a-heat-stable-rotavirus-vaccine-among-children-in-niger-data-from-a-phase-3-randomized-double-blind-placebo-controlled-trial
#12
Matthew E Coldiron, Ousmane Guindo, Rockyath Makarimi, Issaka Soumana, Amadou Matar Seck, Souna Garba, Emilie Macher, Sheila Isanaka, Rebecca F Grais
BACKGROUND: Rotavirus remains a major cause of diarrhea among children under 5 years of age. The efficacy of RotaSIIL, a pentavalent rotavirus vaccine, was shown in an event-driven trial in Niger. We describe the two-year safety follow-up of this trial. METHODS: Follow-up of safety outcomes began upon administration of the first dose of RotaSIIL or placebo. Adverse events were followed until 28 days after the third dose, and serious adverse events were followed until 2 years of age...
May 8, 2018: Vaccine
https://www.readbyqxmd.com/read/29751747/a-fatal-case-associated-with-respiratory-syncytial-virus-infection-in-a-young-child
#13
Lili Xu, Hengmiao Gao, Jiansheng Zeng, Jun Liu, Cong Lu, Xiaolei Guan, Suyun Qian, Zhengde Xie
BACKGROUND: Respiratory syncytial virus (RSV) is the most common viral cause of pediatric bronchiolitis and pneumonia worldwide. Risk factors for high mortality and prolonged morbidity after RSV infection include premature birth, bronchopulmonary dysplasia, congenital heart disease, and Down syndrome. However, some previously healthy, full-term children who are infected with RSV also require hospitalization and even experience severe sequelae or death. CASE PRESENTATION: In this report, we present the case of an RSV-associated death of a child who was born at full-term and developed normally up to the age of 2 years old...
May 11, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29750768/dynamics-of-severe-and-non-severe-invasive-pneumococcal-disease-in-young-children-in-israel-following-pcv7-pcv13-introduction
#14
Daniel Glikman, Ron Dagan, Galia Barkai, Diana Averbuch, Alex Guri, Noga Givon-Lavi, Shalom Ben-Shimol
BACKGROUND: The introduction of the pneumococcal conjugated vaccines (PCVs) resulted in a substantial reduction of invasive pneumococcal disease (IPD) rates. However, impact on non-severe IPD (mostly occult bacteremia) has not yet been fully elucidated.We assessed severe and non-severe IPD (SIPD and NSIPD, respectively) rate dynamics in children <5 years in Israel before and after PCV7/PCV13 implementation. METHODS: A prospective, population-based, nationwide surveillance...
May 10, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29748032/selecting-the-right-indicators-to-ensure-optimised-implementation-of-bcg-vaccination-policy
#15
Sanne Marie Thysen, Ane Bærent Fisker
No abstract text is available yet for this article.
May 7, 2018: Vaccine
https://www.readbyqxmd.com/read/29746452/progress-toward-polio-eradication-worldwide-january-2016-march-2018
#16
Farrah Khan, S Deblina Datta, Arshad Quddus, John F Vertefeuille, Cara C Burns, Jaume Jorba, Steven G F Wassilak
In 1988, when an estimated 350,000 cases of poliomyelitis occurred in 125 countries, the World Health Assembly resolved to eradicate polio globally. Transmission of wild poliovirus (WPV) continues uninterrupted in only three countries (Afghanistan, Nigeria, and Pakistan) (1), and among the three serotypes, WPV type 1 (WPV1) remains the only confirmed circulating type. This report describes global progress toward polio eradication during January 2016-March 2018, and updates previous reports (2). In 2017, 22 WPV1 cases were reported, a 41% decrease from the 37 WPV1 cases reported in 2016...
May 11, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29745749/hpv-vaccination-prevalence-parental-barriers-and-motivators-to-vaccinating-children-in-hawai-i
#17
May Rose Isnec Dela Cruz, Kathryn L Braun, Jo Ann Umilani Tsark, Cheryl Lynn Albright, John J Chen
OBJECTIVE: To determine the prevalence and barriers to human papillomavirus (HPV) vaccine uptake among 11-18 year olds in the Hawai'i's four major ethnic groups-Native Hawaiians, Filipinos, Japanese, and Caucasians. STUDY DESIGN: A telephone survey assessed parents' knowledge of HPV and the HPV vaccine, status of their child's HPV vaccine uptake, variables operationalizing the Health Belief Model, and barriers and motivators to uptake. RESULTS: Across the groups, 799 parents completed the survey...
May 10, 2018: Ethnicity & Health
https://www.readbyqxmd.com/read/29744035/human-metapneumovirus-what-we-know-now
#18
REVIEW
Nazly Shafagati, John Williams
Human metapneumovirus (HMPV) is a leading cause of acute respiratory infection, particularly in children, immunocompromised patients, and the elderly. HMPV, which is closely related to avian metapneumovirus subtype C, has circulated for at least 65 years, and nearly every child will be infected with HMPV by the age of 5. However, immunity is incomplete, and re-infections occur throughout adult life. Symptoms are similar to those of other respiratory viral infections, ranging from mild (cough, rhinorrhea, and fever) to more severe (bronchiolitis and pneumonia)...
2018: F1000Research
https://www.readbyqxmd.com/read/29743373/five-residues-in-the-apical-loop-of-the-respiratory-syncytial-virus-fusion-protein-f-2-subunit-are-critical-for-its-fusion-activity
#19
Stephanie N Hicks, Supranee Chaiwatpongsakorn, Heather M Costello, Jason S McLellan, William Ray, Mark E Peeples
The respiratory syncytial virus (RSV) fusion (F) protein is a trimeric, membrane-anchored glycoprotein capable of mediating both viral-target cell membrane fusion to initiate infection and cell-cell fusion, even in the absence of the attachment glycoprotein. The F protein is initially expressed in a precursor form, whose functional capabilities are activated by proteolysis at two sites between the F1 and F2 subunits. This cleavage results in expression of the metastable and high-energy prefusion conformation...
May 9, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29741721/update-from-the-advisory-committee-on-immunization-practices
#20
Sean T O'Leary, David W Kimberlin, Yvonne A Maldonado
The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts, meets 3 times per year to develop recommendations for vaccine use in the United States. The group has 15 voting members, each of whom is appointed to a 4-year term. ACIP members and Centers for Disease Control and Prevention (CDC) staff discuss the epidemiology of vaccine-preventable diseases and vaccine research, effectiveness, safety data, and clinical trial results. The ACIP met on October 25 and 26, 2017, to discuss herpes zoster vaccine, the child/adolescent and adult vaccination schedules, Japanese encephalitis (JE) epidemiology and vaccines, pneumococcal vaccines, anthrax vaccines and disaster preparedness, hepatitis A outbreaks, influenza surveillance and vaccination coverage, vaccine safety, and considerations for a potential third dose of measles-mumps-rubella (MMR) vaccine to combat ongoing mumps outbreaks...
May 7, 2018: Journal of the Pediatric Infectious Diseases Society
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