keyword
MENU ▼
Read by QxMD icon Read
search

mixed malaria

keyword
https://www.readbyqxmd.com/read/28521791/exploring-the-role-of-socioeconomic-factors-in-the-development-and-spread-of-anti-malarial-drug-resistance-a-qualitative-study
#1
Philip Emeka Anyanwu, John Fulton, Etta Evans, Timothy Paget
BACKGROUND: Malaria remains a global health issue with the burden unevenly distributed to the disadvantage of the developing countries of the world. Poverty contributes to the malaria burden as it has the ability to affect integral aspects of malaria control. There have been renewed efforts in the global malaria control, resulting in reductions in the global malaria burden over the last decade. However, the development of resistance to artemisinin-based combination therapy threatens the sustainability of the present success in malaria control...
May 18, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28502184/promoting-community-malaria-control-in-rural-myanmar-through-an-active-community-participation-program-using-the-participatory-learning-approach
#2
Chan Nyein Maung, Than Tun Sein, Thaung Hlaing, Kamolnetr Okanurak, Tassanee Silawan, Jaranit Kaewkungwal
INTRODUCTION: Malaria is prevalent in more than 80% of townships in Myanmar. The National Malaria Control Programme (NMCP) has been implementing community-based malaria control programs nationwide. However, these programs are mostly developed and directed by health authorities, while communities are passively involved. This study aimed to increase community participation in malaria control and promote community malaria control knowledge and practice in rural Myanmar. METHODS: A community-based study, which employed a mixed method approach, collecting data quantitatively and qualitatively, was conducted in two rural villages...
April 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28497225/development-of-a-rapid-hrm-qpcr-for-the-diagnosis-of-the-four-most-prevalent-plasmodium-lineages-in-new-zealand
#3
E R Schoener, S Hunter, L Howe
Although wildlife rehabilitation and translocations are important tools in wildlife conservation in New Zealand, disease screening of birds has not been standardized. Additionally, the results of the screening programmes are often difficult to interpret due to missing disease data in resident or translocating avian populations. Molecular methods have become the most widespread method for diagnosing avian malaria (Plasmodium spp.) infections. However, these methods can be time-consuming, expensive and are less specific in diagnosing mixed infections...
May 11, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28482891/evaluation-of-efficacy-of-interceptor-%C3%A2-g2-a-long-lasting-insecticide-net-coated-with-a-mixture-of-chlorfenapyr-and-alpha-cypermethrin-against-pyrethroid-resistant-anopheles-gambiae-s-l-in-burkina-faso
#4
Koama Bayili, Severin N'do, Moussa Namountougou, Roger Sanou, Abdoulaye Ouattara, Roch K Dabiré, Anicet G Ouédraogo, David Malone, Abdoulaye Diabaté
BACKGROUND: Malaria vectors have acquired widespread resistance throughout sub-Saharan Africa to many of the currently used insecticides. Hence, there is an urgent need to develop alternative strategies including the development of new insecticides for effective management of insecticide resistance. To maintain progress against malaria, it is necessary to identify other residual insecticides for mosquito nets. In the present WHOPES phase II analogue study, the utility of chlorfenapyr, a pyrrole class insecticide mixed with alpha-cypermethrin on a long-lasting mosquito bed net was evaluated against Anopheles gambiae s...
May 8, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28481286/infectious-diseases-and-tropical-cyclones-in-southeast-china
#5
Jietao Zheng, Weixiao Han, Baofa Jiang, Wei Ma, Ying Zhang
Southeast China is frequently hit by tropical cyclones (TCs) with significant economic and health burdens each year. However, there is a lack of understanding of what infectious diseases could be affected by tropical cyclones. This study aimed to examine the impacts of tropical cyclones on notifiable infectious diseases in southeast China. Disease data between 2005 and 2011 from four coastal provinces in southeast China, including Guangdong, Hainan, Zhejiang, and Fujian province, were collected. Numbers of cases of 14 infectious diseases were compared between risk periods and reference periods for each tropical cyclone...
May 7, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28479922/laboratory-diagnosis-of-malaria-comparison-of-manual-and-automated-diagnostic-tests
#6
Samina Naz Mukry, Madiha Saud, Gul Sufaida, Kashif Shaikh, Arshi Naz, Tahir Sultan Shamsi
Malaria is the second most prevalent disease in Pakistan resulting in ~30,000 annual deaths. In endemic countries like Pakistan precise and timely diagnosis of malaria is imperative to overcome the associated risks of fatal outcomes. Malarial parasite was screened in 128 malaria suspected patients and 150 healthy controls, by species-specific PCR, microscopy of blood smears, hemoanalyzer Sysmex XE-2100, and rapid test devices (First Response Malaria® and ICT Malaria Combo®). The microscopy detected MP in 126 samples (parasite load/µl 386-53712/µl); 71...
2017: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/28479726/anti-plasmodial-and-chloroquine-resistance-suppressive-effects-of-embelin
#7
O I Zaid, R Abd Majid, M S Hasidah, M N Sabariah, K Al-Zihiry, Sattar Rahi, R Basir
BACKGROUND: Emergence of chloroquine (CQ) resistance among different strains of Plasmodium falciparum is the worst catastrophe that has ever perplexed the dedicated efforts to eradicate malaria. This urged the scientists to search for new alternatives or sensitizers to augment its antiplasmodium effect. MATERIALS AND METHOD: In this experiment, the potential of embelin, isolated from Embelia ribes, to inhibit the growth and sensitize CQ action was screened using SYBRE-green-I based drug sensitivity and isobologram assays, respectively...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28464959/temporal-genetic-changes-in-plasmodium-vivax-apical-membrane-antigen-1-over-19%C3%A2-years-of-transmission-in-southern-mexico
#8
Alejandro Flores-Alanis, Lilia González-Cerón, Frida Santillán, Cecilia Ximenez, Marco A Sandoval, René Cerritos
BACKGROUND: Mexico advanced to the pre-elimination phase in 2009 due to a significant reduction in malaria cases, and since 2000, Plasmodium vivax is the only species transmitted. During the last two decades, malaria transmission has been mostly local and isolated to a few regions. It is important to gain further insights into the impact of control measures on the parasite population structure. Hence, the aim of the current study was to determine detailed changes in P. vivax genetic diversity and population structure based on analysing the gene that encodes the apical membrane antigen 1 (pvama1)...
May 2, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28460016/physicians-compliance-with-the-national-drug-policy-on-malaria-in-a-tertiary-teaching-hospital-india-from-2010-to-2015-a-mixed-method-study
#9
Soundappan Kathirvel, Jaya Prasad Tripathy, Zaw Myo Tun, Binod Kumar Patro, Tarundeep Singh, Ashish Bhalla, Mahesh Devnani, Ewan Wilkinson
Background: National drug policies are formulated to encourage rational use of drugs and to reduce drug resistance. This study assessed physicians' compliance with the National Drug Policy on Malaria at a tertiary care hospital in north India. Methods: This mixed method study extracted data from adult malaria inpatient records of the hospital from 2010-2015, and assessed drug supply at pharmacies. Physicians' practices and perspectives were explored by in-depth interviews...
February 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28454537/increase-in-the-prevalence-of-mutations-associated-with-sulfadoxine-pyrimethamine-resistance-in-plasmodium-falciparum-isolates-collected-from-early-to-late-pregnancy-in-nanoro-burkina-faso
#10
Esmée Ruizendaal, Marc C Tahita, Ronald B Geskus, Inge Versteeg, Susana Scott, Umberto d'Alessandro, Palpouguini Lompo, Karim Derra, Maminata Traore-Coulibaly, Menno D de Jong, Henk D F H Schallig, Halidou Tinto, Petra F Mens
BACKGROUND: Pregnant women are a high-risk group for Plasmodium falciparum infections, which may result in maternal anaemia and low birth weight newborns, among other adverse birth outcomes. Intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy (IPTp-SP) is widely implemented to prevent these negative effects of malaria. However, resistance against SP by P. falciparum may decrease efficacy of IPTp-SP. Combinations of point mutations in the dhps (codons A437, K540) and dhfr genes (codons N51, C59, S108) of P...
April 28, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28449641/cell-free-hemoglobin-mediated-oxidative-stress-is-associated-with-acute-kidney-injury-and-renal-replacement-therapy-in-severe-falciparum-malaria-an-observational-study
#11
Katherine Plewes, Hugh W F Kingston, Aniruddha Ghose, Richard J Maude, M Trent Herdman, Stije J Leopold, Haruhiko Ishioka, Md Mahtab Uddin Hasan, Md Shafiul Haider, Shamsul Alam, Kim A Piera, Prakaykaew Charunwatthana, Kamolrat Silamut, Tsin W Yeo, Md Abul Faiz, Sue J Lee, Mavuto Mukaka, Gareth D H Turner, Nicholas M Anstey, L Jackson Roberts, Nicholas J White, Nicholas P J Day, Md Amir Hossain, Arjen M Dondorp
BACKGROUND: Intravascular hemolysis is an intrinsic feature of severe malaria pathophysiology but the pathogenic role of cell-free hemoglobin-mediated oxidative stress in severe malaria associated acute kidney injury (AKI) is unknown. METHODS: As part of a prospective observational study, enrolment plasma cell-free hemoglobin (CFH), lipid peroxidation markers (F2-isoprostanes (F2-IsoPs) and isofurans (IsoFs)), red cell deformability, and serum creatinine were quantified in Bangladeshi patients with severe falciparum malaria (n = 107), uncomplicated malaria (n = 80) and sepsis (n = 28)...
April 27, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28441956/what-happened-to-anti-malarial-markets-after-the-affordable-medicines-facility-malaria-pilot-trends-in-act-availability-price-and-market-share-from-five-african-countries-under-continuation-of-the-private-sector-co-payment-mechanism
#12
Sarah Tougher, Kara Hanson, Catherine Goodman
BACKGROUND: The private sector supplies anti-malarial treatment for large proportions of patients in sub-Saharan Africa. Following the large-scale piloting of the Affordable Medicines Facility-malaria (AMFm) from 2010 to 2011, a private sector co-payment mechanism (CPM) provided continuation of private sector subsidies for quality-assured artemisinin combination therapies (QAACT). This article analyses for the first time the extent to which improvements in private sector QAACT supply and distribution observed during the AMFm were maintained or intensified during continuation of the CPM through 2015 in Kenya, Madagascar, Nigeria, Tanzania and Uganda using repeat cross-sectional outlet survey data...
April 25, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28438169/ivermectin-and-malaria-control
#13
Satoshi Ōmura, Andy Crump
As the world begins to realize the very real prospect of eliminating malaria as a public health problem globally, the scientific community is acutely aware that novel and innovative new tools will be required if that lofty goal is to be accomplished. Moreover, the need for comprehensive, integrated products and interventions is being recognized in order for the critical 'final steps' toward elimination to be taken successfully. Failure to take these crucial last steps have dogged all past global disease elimination programmes, except for smallpox...
April 24, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28438155/the-malaria-testing-and-treatment-landscape-in-the-southern-lao-people-s-democratic-republic-pdr
#14
Saysana Phanalasy
BACKGROUND: In the context of national and regional goals to eliminate malaria by 2030, the Center for Malaria Parasitology and Entomology in the Lao PDR is implementing strategies to ensure all malaria cases are detected and appropriately treated with first-line artemisinin combination therapy, artemether-lumefantrine (AL). Timely and relevant evidence to inform policies and strategies is needed to ensure the most effective and efficient use of resources, and to accelerate progress towards elimination goals...
April 25, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28437083/dual-plug-and-display-synthetic-assembly-using-orthogonal-reactive-proteins-for-twin-antigen-immunization
#15
Karl D Brune, Can M Buldun, Yuanyuan Li, Iona J Taylor, Florian Brod, Sumi Biswas, Mark Howarth
Engineering modular platforms to control biomolecular architecture can advance both the understanding and the manipulation of biological systems. Icosahedral particles uniformly displaying single antigens stimulate potent immune activation and have been successful in various licensed vaccines. However, it remains challenging to display multiple antigens on a single particle and to induce broader immunity protective across strains or even against distinct diseases. Here, we design a dually addressable synthetic nanoparticle by engineering the multimerizing coiled-coil IMX313 and two orthogonally reactive split proteins...
May 5, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/28431108/investments-in-children-s-health-and-the-kenyan-cash-transfer-for-orphans-and-vulnerable-children-evidence-from-an-unconditional-cash-transfer-scheme
#16
Carolyn Huang, Kavita Singh, Sudhanshu Handa, Carolyn Halpern, Audrey Pettifor, Harsha Thirumurthy
Child mortality is one of the most pressing global health and policy issues in the developing world. The leading drivers of death-pneumonia, diarrhea and malaria-are preventable and treatable. However, these illnesses are exacerbated by a lack of accessible nutrition, water, basic and preventive health services, and sanitary living conditions-all factors which are more likely to disproportionately impact the poor. We examine whether Kenya's largest social protection impacts children's incidence of upper respiratory illness...
April 18, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28427455/comparison-of-methods-for-detecting-asymptomatic-malaria-infections-in-the-china-myanmar-border-area
#17
Yonghong Zhao, Yan Zhao, Yanmin Lv, Fei Liu, Qinghui Wang, Peipei Li, Zhenjun Zhao, Yingjie Liu, Liwang Cui, Qi Fan, Yaming Cao
BACKGROUND: Sensitive methods for detecting asymptomatic malaria infections are essential for identifying potential transmission reservoirs and obtaining an accurate assessment of malaria epidemiology in low-endemicity areas aiming to eliminate malaria. PCR techniques to detect parasite nucleic acids (DNA or RNA) are among the most commonly used molecular methods. However, most of these methods are of low throughput and cannot be used for large-scale molecular epidemiological studies...
April 20, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28423028/four-human-plasmodium-species-quantification-using-droplet-digital-pcr
#18
Suttipat Srisutham, Naowarat Saralamba, Benoit Malleret, Laurent Rénia, Arjen M Dondorp, Mallika Imwong
Droplet digital polymerase chain reaction (ddPCR) is a partial PCR based on water-oil emulsion droplet technology. It is a highly sensitive method for detecting and delineating minor alleles from complex backgrounds and provides absolute quantification of DNA targets. The ddPCR technology has been applied for detection of many pathogens. Here the sensitive assay utilizing ddPCR for detection and quantification of Plasmodium species was investigated. The assay was developed for two levels of detection, genus specific for all Plasmodium species and for specific Plasmodium species detection...
2017: PloS One
https://www.readbyqxmd.com/read/28420446/immune-resistance-and-tolerance-strategies-in-malaria-vector-and-non-vector-mosquitoes
#19
Tibebu Habtewold, Zoe Groom, George K Christophides
BACKGROUND: The Anopheles gambiae complex consists of species that vary greatly in their capacity to transmit malaria. The mosquito immune system has been identified as a key factor that can influence whether Plasmodium infection establishes within the mosquito vector. This study was designed to investigate the immune responses of An. coluzzii, An. arabiensis and An. quadriannulatus mosquitoes. The first two mosquito species are major vectors of malaria in sub-Saharan Africa, while the third is thought to be a non-vector...
April 18, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28420422/high-resolution-melting-a-useful-field-deployable-method-to-measure-dhfr-and-dhps-drug-resistance-in-both-highly-and-lowly-endemic-plasmodium-populations
#20
Yaye Dié Ndiaye, Cyrille K Diédhiou, Amy K Bei, Baba Dieye, Aminata Mbaye, Nasserdine Papa Mze, Rachel F Daniels, Ibrahima M Ndiaye, Awa B Déme, Amy Gaye, Mouhamad Sy, Tolla Ndiaye, Aida S Badiane, Mouhamadou Ndiaye, Zul Premji, Dyann F Wirth, Souleymane Mboup, Donald Krogstad, Sarah K Volkman, Ambroise D Ahouidi, Daouda Ndiaye
BACKGROUND: Emergence and spread of drug resistance to every anti-malarial used to date, creates an urgent need for development of sensitive, specific and field-deployable molecular tools for detection and surveillance of validated drug resistance markers. Such tools would allow early detection of mutations in resistance loci. The aim of this study was to compare common population signatures and drug resistance marker frequencies between two populations with different levels of malaria endemicity and history of anti-malarial drug use: Tanzania and Sénégal...
April 19, 2017: Malaria Journal
keyword
keyword
98834
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"