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https://www.readbyqxmd.com/read/27911065/-gastric-tube-esophagoplasty-using-the-retroesternal-route-in-children
#1
L García Martínez, J A Molino Gahete, S Redecillas Ferreiro, E Bordón Cabrera, J Bueno Recio, G Guillén Burrieza, C Giné Prades, A Lara Valtueña, J Lloret Roca
INTRODUCTION: Esophageal replacement is a surgical alternative once native esophagus can't be preserved. Different organs and routes for the replacement have been described, being the retroesternal route the least used. The aim is to present our results using gastric tube esophagoplasty with a retroesternal approach. PATIENTS AND METHODS: We performed a retrospective and descriptive study of 11 patients operated from 2000 to 2015. Median age at surgery was 2.2 years (5 months-9 years) and median weight was 11...
January 25, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/27904785/overexpression-of-ywhaz-as-an-independent-prognostic-factor-in-adenocarcinoma-of-the-esophago-gastric-junction
#2
Nobuyuki Watanabe, Shuhei Komatsu, Daisuke Ichikawa, Mahito Miyamae, Takuma Ohashi, Wataru Okajima, Toshiyuki Kosuga, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Kazuma Okamoto, Hitoshi Tsuda, Eigo Otsuji
Several studies have demonstrated that YWHAZ (14-3-3ζ), included in the 14-3-3 family of proteins, is implicated in the initiation and progression of cancers. To detect a novel treatment target for adenocarcinoma of the esophagogastric junction (AEG), we tested whether YWHAZ acted as a cancer-promoting gene through its overexpression in AEG. We analyzed YWHAZ protein expression in 92 consecutive primary AEG tumors, which had been curatively resected in our institution between 2000 and 2010. Overexpression of the YWHAZ protein was frequently detected in primary AEG tumor samples (46% (42/92))...
2016: American Journal of Cancer Research
https://www.readbyqxmd.com/read/27812069/frequency-of-different-types-of-gastric-varices-in-patients-with-cirrhosis-due-to-chronic-hepatitis-c
#3
Zamir Butt, Syed Muhammad Ali Shah, Muhammad Afzal, Irfan Younis, Muhammad Waqas, Hamna Atta
OBJECTIVE: To determine the frequency of different types of gastric varices in patients with hepatitis C virus-related cirrhosis. METHODS: The observational cross-sectional study was conducted from August 2014 to August 2015 at Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan, using non-probability consecutive sampling. Patients having liver cirrhosis only due to chronic hepatitis C virus, portal vein diameter >12mm or spleen size >12cm in long axis and ascites with no previous history of variceal banding were included...
November 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27760947/-a-case-of-her2-positive-siewert-type-i-adenocarcinoma-of-the-esophagogastric-junction-treated-via-neoadjuvant-chemotherapy-followed-by-radical-resection
#4
Tetsushi Nakajima, Tsutomu Sato, Kazuki Kano, Yukio Maezawa, Kenki Segami, Hirohito Fujikawa, Kousuke Ikeda, Takanobu Yamada, Takashi Ogata, Haruhiko Cho, Takaki Yoshikawa
A 63-year-old man with dysphagia was referred to our hospital. He was found to have a type 2 tumor extending from the lower thoracic esophagus to the esophagogastric junction via upper gastrointestinal endoscopy. A biopsy revealed adenocarcinoma with overexpression of the human epidermal growth factor type 2(HER2). The tumor was type I according to Siewert's classification, as the epicenter of the tumor was 27mm to the oral side from the esophago-gastric junction. The clinical diagnosis was T3N1M1, stage IV according to the Japanese Classification of Gastric Carcinoma, and T3N2M0, stage III per the Japanese Classification of Esophageal Cancer...
October 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/27759350/pernicious-anaemia-with-gastric-carcinoids
#5
Shaik Jani Basha, N R Shetty, Harshad Devarbhavi
We report the case of a 42 year male with history of chronic anaemia who was found to have pernicious anaemia with beta thalassemia trait and had on esophago-gastric-duodenoscopy, gastric carcinoids with gastric atrophy. Pernicious anaemia and gastric carcinoids occurring simultaneously in a single individual is rare. Our case emphasises the need for esophago-gastric-duodenoscopy in cases of pernicious anaemia.
July 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27723702/-thoracolaparoscopic-extirpation-of-the-esophagus-with-simultaneous-repair-using-colonic-segment-and-esophago-colostomy-on-the-neck
#6
I E Khat'kov, R E Izrailov, S A Domrachev, P V Kononets, M A Koshkin
No abstract text is available yet for this article.
2016: Khirurgiia
https://www.readbyqxmd.com/read/27716069/should-every-region-use-the-same-gastric-cancer-scanning-and-treatment-approaches-let-s-reconsider-a-northeastern-turkey-example
#7
Albayrak Fatih, Ozturk Yasin, Dursun Hakan, Albayrak Yavuz
BACKGROUND: The rate for upper gastrointestinal (UGI) cancers, and especially the rate for gastric cancer, varies from country to country and from region to region within country. In Turkey, the incidence of gastric cancer varies widely among regions due to the diverse cultures and accompanying food habits of the population. This study aimed to determine the endoscopic frequency of esophageal and gastric cancers and the usefulness of alarm symptoms in diagnosing gastric cancer in subjects undergoing endoscopy in northeastern Turkey...
October 4, 2016: BMC Gastroenterology
https://www.readbyqxmd.com/read/27678357/seventh-tumor-node-metastasis-staging-of-gastric-cancer-five-year-follow-up
#8
REVIEW
Stefano Rausei, Laura Ruspi, Federica Galli, Vincenzo Pappalardo, Giuseppe Di Rocco, Francesco Martignoni, Francesco Frattini, Francesca Rovera, Luigi Boni, Gianlorenzo Dionigi
Seventh tumor-node-metastasis (TNM) classification for gastric cancer, published in 2010, introduced changes in all of its three parameters with the aim to increase its accuracy in prognostication. The aim of this review is to analyze the efficacy of these changes and their implication in clinical practice. We reviewed relevant Literature concerning staging systems in gastric cancer from 2010 up to March 2016. Adenocarcinoma of the esophago-gastric junction still remains a debated entity, due to its peculiar anatomical and histological situation: further improvement in its staging are required...
September 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27669530/multimodal-endoscopic-treatment-of-primary-esophago-pleural-fistula
#9
Helga Bertani, Giuseppe Grande, Vincenzo Giorgio Mirante, Isabella Franco, Santi Mangiafico, Raffaele Manta, Rita Luisa Conigliaro
No abstract text is available yet for this article.
January 2016: Endoscopy
https://www.readbyqxmd.com/read/27660053/do-jackhammer-contractions-lead-to-achalasia-a-longitudinal-study
#10
L Huang, M Pimentel, A Rezaie
BACKGROUND: Jackhammer esophagus (JE) is a rare esophageal motility disorder defined in the Chicago Classification of Esophageal Motility by presence of excessively high distal contractile integral (DCI) on high-resolution manometry (HRM), with unknown natural manometric course. We examined the development of achalasia over time in patients with JE. METHODS: Through a retrospective longitudinal design, patients with Jackhammer contractions who had more than one HRM between 2005 and 2015 were identified...
September 23, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27652174/downward-trend-in-the-prevalence-of-helicobacter-pylori-infections-and-corresponding-frequent-upper-gastrointestinal-diseases-profile-changes-in-southeastern-china-between-2003-and-2012
#11
Jian-Xia Jiang, Qing Liu, Xin-Yi Mao, Hai-Han Zhang, Guo-Xin Zhang, Shun-Fu Xu
This present study aims to determine trends in the prevalence of H. pylori infections in Southeastern China between 2003 and 2012, and investigate corresponding changes in the prevalence of upper gastrointestinal diseases. This retrospective study screened 196,442 patients with a mean age of 47.49 ± 14.47 years (age range 5-100 years) in Southeastern China, and a total of 134,812 cases of an endoscopy-referral patient population with digestive symptoms between 2003 and 2012 were enrolled. Based on esophago-gastro-duodenoscopy and pathology, patients diagnosed with chronic gastritis, peptic ulcer, gastric cancer or reflux esophagitis were included in this study...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27634013/characterization-and-mechanisms-of-the-pharyngeal-swallow-activated-by-stimulation-of-the-esophagus
#12
Ivan M Lang, Bidyut K Medda, Sudarshan R Jadcherla, Reza Shaker
Stimulation of the esophagus activates the pharyngeal swallow response (EPSR) in human infants and animals. The aims of this study were to characterize the stimulus and response of the EPSR and to determine the function and mechanisms generating the EPSR. Studies were conducted in 46 decerebrate cats in which pharyngeal, laryngeal, and esophageal motility was monitored using EMG, strain gauges, or manometry. The esophagus was stimulated by balloon distension or luminal fluid infusion. We found that esophageal distension increased the chance of occurrence of the EPSR, but the delay was variable...
November 1, 2016: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/27585290/length-of-endoscopic-workup-in-gastrointestinal-bleeding
#13
Zibing Woodward, J Lucas Williams, Amnon Sonnenberg
BACKGROUND: The number of procedures utilized in the general management of gastrointestinal bleeding (GIB) has not been investigated previously. We used the National Endoscopic Database of the Clinical Outcomes Research Initiative for an observational study to analyze the average length of workup in GIB. METHODS: The electronic database was queried for all patients aged 18 years and older who underwent an endoscopic evaluation for any bleeding indication between 2000 and 2014...
October 2016: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27523737/prolonged-measurement-improves-the-assessment-of-the%C3%A2-barrier-function-of-the-esophago-gastric-junction-by-high-resolution-manometry
#14
D Jasper, N Freitas-Queiroz, M Hollenstein, B Misselwitz, P Layer, T Navarro-Rodriguez, M Fox, J Keller
BACKGROUND: Etiology of gastro-esophageal reflux disease (GERD) is multifactorial, but incompetence of the esophago-gastric junction (EGJ) appears to be of crucial importance. Established manometric parameters for assessment of EGJ barrier function are sub-optimal, potentially because they reflect only a very brief (up to 30 seconds), not necessarily representative period. This prospective, case-control study tested the performance of novel, high-resolution manometry (HRM) parameters of EGJ function in the assessment of GERD...
August 14, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27517748/herg1-behaves-as-biomarker-of-progression-to-adenocarcinoma-in-barrett-s-esophagus-and-can-be-exploited-for-a-novel-endoscopic-surveillance
#15
Elena Lastraioli, Tiziano Lottini, Jessica Iorio, Giancarlo Freschi, Marilena Fazi, Claudia Duranti, Laura Carraresi, Luca Messerini, Antonio Taddei, Maria Novella Ringressi, Marianna Salemme, Vincenzo Villanacci, Carla Vindigni, Anna Tomezzoli, Roberta La Mendola, Maria Bencivenga, Bruno Compagnoni, Mariella Chiudinelli, Luca Saragoni, Ilaria Manzi, Giovanni De Manzoni, Paolo Bechi, Luca Boni, Annarosa Arcangeli
Barrett's esophagus (BE) is the only well-known precursor lesion of esophageal adenocarcinoma (EA). The exact estimates of the annual progression rate from BE to EA vary from 0.07% to 3.6%. The identification of BE patients at higher risk to progress to EA is hence mandatory, although difficult to accomplish. In search of novel BE biomarkers we analyzed the efficacy of hERG1 potassium channels in predicting BE progression to EA. Once tested by immunohistochemistry (IHC) on bioptic samples, hERG1 was expressed in BE, and its expression levels increased during progression from BE to esophageal dysplasia (ED) and EA...
August 9, 2016: Oncotarget
https://www.readbyqxmd.com/read/27501598/comparison-of-spraying-and-nebulized-lidocaine-in-patients-undergoing-esophago-gastro-duodenoscopy-a-randomized-trial
#16
RANDOMIZED CONTROLLED TRIAL
Papiroon Noitasaeng, Phongthara Vichitvejpaisal, Uaypom Kaosombatwattana, Jaiyen Tassanee, Siriwongsa Suwannee
OBJECTIVE: Esophago-gastro-duodenoscopy (EGD) was performed under the topical anesthesia of the pharynx. However spraying lidocaine was found to be an annoying maneuver to patients, while nebulized lidocaine appeared to efficiently suppress gags and cough reflexes in airway anesthesia. This study aimed to compare the effectiveness of spraying and nebulized lidocaine for patients undergoing EGD. MATERIAL AND METHOD: A total of 110 patients undergoing elective EGD, with a history of neither lidocaine intolerance nor irritable airways due to smoking, chronic obstructive pulmonary disease (COPD), upper respiratory infection, asthma, cardiac and pulmonary diseases and allergy to lidocaine were included...
May 2016: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/27474099/cervical-esophago-gastric-tubes-for-patients-with-malignant-ascites
#17
Diana H Liang, Min P Kim, Edward Y Chan, Puja Gaur
Patients with chronic small bowel obstruction and malignant ascites from diffuse peritoneal carcinomatosis have limited options for gastrointestinal decompression as part of end-of-life palliation. Insertion of a percutaneous gastrostomy tube is relatively contraindicated in patients with ascites. Alternatively, nasogastric tube placement often leads to significant discomfort to patients and necessitates hospitalization during their last days of life. Here, we demonstrate how placing a percutaneous cervical esophago-gastric tube can allow adequate gastrointestinal decompression for terminal patients with malignant small bowel obstruction...
July 29, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27422826/a-physiological-model-for-the-investigation-of-esophageal-motility-in-healthy-and-pathologic-conditions
#18
Emanuele Luigi Carniel, Alessandro Frigo, Mario Costantini, Tommaso Giuliani, Loredana Nicoletti, Stefano Merigliano, Arturo N Natali
Recent technological advances in esophageal manometry allowed the definition of new classification methods for the diagnosis of disorders of esophageal motility and the implementation of innovative computational tools for the autonomic, reliable and unbiased detection of different disorders. Computational models can be developed aiming to interpret the mechanical behavior and functionality of the gastrointestinal tract and to summarize the results from clinical measurements, as high-resolution manometry pressure plots, into model parameters...
July 15, 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/27412126/are-single-or-dual-luminal-covered-expandable-metallic-stents-suitable-for-esophageal-squamous-cell-carcinoma-with-esophago-airway-fistula
#19
Pei-Ming Huang, Jang-Ming Lee
BACKGROUND: To analyze the outcomes of single or dual luminal self-expandable covered metallic stents (SECMS) for palliative treatment for esophageal cancer with esophago-airway fistula (EAF). METHODS: We retrospectively assessed 50 patients who underwent SECMS placement for malignant EAF at our institution between June 2005 and December 2014 to define clinical results of stenting. Treatment provided was classified into initial single airway, single esophageal, or double stent placement...
July 13, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27390847/a-phase-ib-ii-study-evaluating-the-combination-of-weekly-docetaxel-and-cisplatin-together-with-capecitabine-and-bevacizumab-in-patients-with-advanced-esophago-gastric-cancer
#20
Baruch Brenner, Michal Sarfaty, Ofer Purim, Yulia Kundel, Limor Amit, Amir Abramovich, Udi Sadeh Gonik, Efraim Idelevich, Noa Gordon, Gal Medalia, Aaron Sulkes
INTRODUCTION: Current treatment options for advanced esophagogastric cancer (AEGC) are still unsatisfactory. The aim of this prospective phase Ib/II study was to evaluate the safety and efficacy of a novel regimen, AVDCX, consisting of weekly docetaxel and cisplatin together with capecitabine and bevacizumab, in AEGC. METHODS: Patients with AEGC received treatment with different dose levels of AVDCX (cisplatin and docetaxel 25-35 mg/m2, days 1,8, capecitabine 1,600 mg/m2 days 1-14, bevacizumab 7...
2016: PloS One
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