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https://www.readbyqxmd.com/read/28329102/single-leaflet-reconstruction-of-pulmonic-valve-with-decellurized-bovine-pericardium
#1
Jonathan M Tomasko, J Scott Rankin, S Chris Malaisrie
A patient presented with a complex mass seen extending from the lumen of the aorta to the lumen of the pulmonary artery. Papillary fibroelastoma was identified at resection, however the left pulmonary valve leaflet required resection to fully remove the mass. The leaflet was reconstructed using the bovine pericardial extracellular matrix. Valve function and flow characteristics were excellent following repair.
February 17, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28316101/n-terminal-pro-b-type-natriuretic-peptide-and-phonocardiography-in-differentiating-innocent-cardiac-murmurs-from-congenital-cardiac-anomalies-in-asymptomatic-puppies
#2
S M Marinus, H van Engelen, V Szatmári
BACKGROUND: Differentiating innocent cardiac murmurs from murmurs caused by congenital cardiac anomalies can be challenging with auscultation alone in asymptomatic puppies. HYPOTHESIS: Plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations and phonocardiograms recorded by an electronic stethoscope can differentiate innocent from pathologic cardiac murmurs. ANIMALS: A total of 186 client-owned asymptomatic dogs: 135 Cairn Terriers (age: 45-124 days), 20 adult Cairn Terriers (age: 7...
March 18, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28277319/evaluation-of-pulmonary-artery-pressure-measurements-in-severe-pulmonic-valve-insufficiency-in-the-absence-of-tricuspid-regurgitation
#3
Kiri Mackersey, Nikolaos Skubas, Adam Lichtman
No abstract text is available yet for this article.
March 8, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28256252/full-development-of-consequences-of-congenital-pulmonic-stenosis-in-eighty-four-years
#4
William C Roberts, Paul A Grayburn, Joseph M Guileyardo, Robert C Stoler
Described herein is an 84-year-old woman, the oldest reported, with severe pulmonic stenosis who underwent a highly successful pulmonic valvotomy at age 77 and highly unsuccessfully attempted percutaneous pulmonic valve implantation at age 84. During the 84 years she developed nearly all clinical and morphologic consequence of pulmonic stenosis, including heavy calcification of the pulmonic valve, heavy calcification of the tricuspid valve annulus, severe right ventricular wall thickening without ventricular cavity dilation, aneurysm of the pulmonary truck, multiple focal ventricular wall scars without narrowing of the epicardial coronary arteries, wall thickening and luminal narrowing of the intramural coronary arteries, and extremely low 12-lead QRS electrocardiographic voltage...
January 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28094152/use-of-3d-printer-technology-to-facilitate-surgical-correction-of-a-complex-vascular-anomaly-with-esophageal-entrapment-in-a-dog
#5
A Dundie, G Hayes, P Scrivani, L Campoy, D Fletcher, K Ash, E Oxford, N S Moïse
A 10 week old female intact Staffordshire terrier was presented with a total of five congenital cardio-thoracic vascular anomalies consisting of a patent ductus arteriosus (PDA) with an aneurysmic dilation, pulmonic stenosis, persistent right aortic arch, aberrant left subclavian artery and persistent left cranial vena cava. These abnormalities were identified with a combination of echocardiogram and computed tomography angiography (CTA). The abnormalities were associated with esophageal entrapment, regurgitation, and volume overload of the left heart with left atrial and ventricular enlargement...
January 13, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28046446/su-c-202-06-design-and-development-of-a-non-rigid-phantom-ventilating-air-quantitatively-evaluating-ct-based-pulmonary-ventilation-imaging
#6
S Miyakawa, H Tachibana, S Moriya, T Kurosawa, M Sato
PURPOSE: A validation study using human or sheep for CT pulmonary ventilation (CT-V) imaging are inefficient and partially unstable. In this study, we designed and developed non-rigid phantom ventilating air to quantitatively evaluate the CT-V image. METHODS: The phantom consisted of an acryl cylinder filled with polyurethane foam designed to pulmonic alveoli and a polyurethane membrane was attached to the inferior end of the phantom to simulate a lung diaphragm...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28038838/-interventional-cardiac-catheterization-in-congenital-heart-disease
#7
François Godart, Ali Houeijeh
Interventional cardiac catheterization has a major place in the management of congenital heart disease. Since the Rashkind atrioseptostomy in mid-1960s, many techniques have been developed. For some, it is necessary to close a cardiac or extracardiac shunt using occluder (double disc system, plug, coil…): closure of atrial septal defect, ventricular septal defect or patent arterial duct. For others, it is necessary to treat a valvular or vascular stenosis using a balloon catheter: dilatation of the pulmonary or the aortic valve, dilatation of aortic coarctation...
December 27, 2016: La Presse Médicale
https://www.readbyqxmd.com/read/28027277/multi-organ-involvement-confounding-the-diagnosis-of-bartonella-henselae-infective-endocarditis-in-children-with-congenital-heart-disease
#8
Christopher P Ouellette, Sarita Joshi, Karen Texter, Preeti Jaggi
Two children with congenital heart disease status-post surgical correction presented with prolonged constitutional symptoms, hepatosplenomegaly and pancytopenia. Concern for malignancy prompted bone marrow biopsies that were without evidence thereof. In case #1, echocardiography identified a multilobulated vegetation on the conduit valve. In case #2, transthoracic, transesophageal and intracardiac echocardiography were performed and were without evidence of cardiac vegetations, however pulmonic emboli raised concern for infective endocarditis...
December 23, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27978815/origin-and-diversification-of-lake-ohrid-s-endemic-acroloxid-limpets-the-role-of-geography-and-ecology
#9
Björn Stelbrink, Alena A Shirokaya, Kirstin Föller, Thomas Wilke, Christian Albrecht
BACKGROUND: Ancient Lake Ohrid, located on the Albania-Macedonia border, is the most biodiverse freshwater lake in Europe. However, the processes that gave rise to its extraordinary endemic biodiversity, particularly in the species-rich gastropods, are still poorly understood. A suitable model taxon to study speciation processes in Lake Ohrid is the pulmonate snail genus Acroloxus, which comprises two morphologically distinct and ecologically (vertically) separated endemic species. Using a multilocus phylogenetic framework of Acroloxus limpets from the Euro-Mediterranean subregion, together with molecular-clock and phylogeographic analyses of Ohrid taxa, we aimed to infer their geographic origin and the timing of colonization as well as the role of geography and ecology in intra-lacustrine diversification...
December 15, 2016: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/27941967/biompha-lamp-a-new-rapid-loop-mediated-isothermal-amplification-assay-for-detecting-schistosoma-mansoni-in-biomphalaria-glabrata-snail-host
#10
Javier Gandasegui, Pedro Fernández-Soto, Juan Hernández-Goenaga, Julio López-Abán, Belén Vicente, Antonio Muro
BACKGROUND: Schistosomiasis remains one of the most common endemic parasitic diseases affecting over 230 million people worlwide. Schistosoma mansoni is the main species causing intestinal and hepatic schistosomiasis and the fresh water pulmonate snails of the genus Biomphalaria are best known for their role as intermediate hosts of the parasite. The development of new molecular monitoring assays for large-scale screening of snails from transmission sites to detect the presence of schistosomes is an important point to consider for snail control interventions related to schistosomiasis elimination...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27913078/pulmonary-artery-dissection-following-balloon-valvuloplasty-in-a-dog-with-pulmonic-stenosis
#11
K A Grint, H B Kellihan
A 3-month-old, 9.9 kg, male pit bull cross was referred for evaluation of collapse. A left basilar systolic heart murmur graded V/VI and a grade IV/VI right basilar systolic heart murmur were ausculted. Echocardiography showed severe pulmonic stenosis characterized by annular hypoplasia, leaflet thickening, and leaflet fusion. After 1 month of atenolol therapy, a pulmonic valve balloon valvuloplasty procedure was performed, and the intra-operative right ventricular pressure was reduced by 43%. Echocardiography, performed the following day, showed apparent rupture of a pulmonary valve leaflet and a membranous structure within the pulmonary artery consistent with a dissecting membrane...
November 30, 2016: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/27904959/differential-pulmonic-nk-and-nkt-cell-responses-in-schistosoma-japonicum-infected-mice
#12
Hefei Cha, Wenjuan Qin, Quan Yang, Hongyan Xie, Jiale Qu, Mei Wang, Daixiong Chen, Fang Wang, Nuo Dong, Longhua Chen, Jun Huang
Natural killer cells (NK cells) and natural killer T cells (NKT cells) play a role in anti-infection, anti-tumor, transplantation immunity, and autoimmune regulation. However, the role of NK and NKT cells during Schistosoma japonicum (S. japonicum) infection has not been widely reported, especially regarding lung infections. The aim of this study was to research the NK and NKT cell response to S. japonicum infection in the lungs of mice. Using immunofluorescent histological analysis, NK and NKT cells were found near pulmonary granulomas...
February 2017: Parasitology Research
https://www.readbyqxmd.com/read/27891743/ingressive-speech-errors-a-service-evaluation-of-speech-sound-therapy-in-a-child-aged-4-6
#13
Laura Hrastelj, Rachael-Anne Knight
BACKGROUND: A pattern of ingressive substitutions for word-final sibilants can be identified in a small number of cases in child speech disorder, with growing evidence suggesting it is a phonological difficulty, despite the unusual surface form. Phonological difficulty implies a problem with the cognitive process of organizing speech into sound contrasts. AIMS: To evaluate phonological therapy approaches in the remediation of non-pulmonic speech errors. Thus, adding to evidence concerning the nature of ingressive substitutions and their remediation whilst highlighting their occurrence within child speech disorder population for practising and training speech and language therapists...
November 27, 2016: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/27885742/catheter-ablation-in-the-right-ventricular-outflow-tract-associated-with-occlusion-of-left-anterior-descending-coronary-artery
#14
Daniel Benhayon, Eyal Nof, William W Chik, Francis Marchlinski
Major vessel injury during right ventricular outflow tract ablation is not something widely recognized, and routine evaluation of the left anterior descending (LAD) artery location in relation to the septal right ventricle is not routinely performed. In the present article, we report a case of acute LAD occlusion after right ventricular outflow tract ablation and then illustrate the intimately close relationship of the LAD artery to the anterior septal site of the RVOT (approximately 2-3 cm under the pulmonic valve), using a combination of intracardiac echocardiography and 3-dimensional electroanatomical mapping recorded during a second case, in order to specifically point to the area at risk...
November 25, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/27859331/two-dimensional-echocardiographic-right-ventricle-measurements-adjusted-to-body-mass-index-and-surface-area-in-a-normal-population
#15
Masood Eslami, Farnoush Larti, Mehrdad Larry, Parisa Molaee, Roya Sattarzadeh Badkoobeh, Anahita Tavoosi, Saeed Safari, Amir Farhang Zand Parsa
BACKGROUND: To determine reference echocardiographic values in a normal population and assess their correlation with body mass index (BMI) and body surface area. METHODS: An expert cardiologist performed two-dimensional echocardiography with triplicate right ventricle (RV) size measurements in 80 subjects with normal heart condition. Results were correlated with anthropometric data. RESULTS: Base-to-apex length in four-chamber view (RVD3) and above-pulmonic valve in short-axis view in males, as well as mid-RV diameter in standard four-chamber view (RVD), basal RV diameter, and mid RV diameter in RV-focused four-chamber view in females, were significantly correlated with BMI...
November 14, 2016: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/27852341/larval-digenean-preferences-in-two-sympatric-snail-species-at-differing-tidal-levels-off-the-atlantic-coast-of-patagonia
#16
G Di Giorgio, C Gilardoni, E Bagnato, F Cremonte, C Ituarte
Larval stages of the trematodes Maritrema madrynense and Hemiuroidea fam. gen. et sp. differentially parasitized Siphonaria lessonii and S. lateralis, two sympatric pulmonate snail species on the rocky intertidal shore at Puerto Deseado, south-western Atlantic coast of Patagonia, Argentina. Snail specimens were collected at two sampling sites with contrasting physical-chemical characteristics. One site, in the upper intertidal, was exposed to sewage from fish-processing plants, greater hydrodynamic forcing and desiccation, a wider temperature range, longer exposure to ultraviolet radiation and higher abundance of birds...
November 17, 2016: Journal of Helminthology
https://www.readbyqxmd.com/read/27802862/isolated-pulmonary-valve-endocarditis-masquerading-as-community-acquired-pneumonia
#17
Salik Nazir, Saroj Lohani, Niranjan Tachamo, Anam Siddiqui, Nitin Patel
Isolated pulmonary valve endocarditis in intravenous drug users is a rarely reported phenomenon. We present the case of a 25-year-old male with history of intravenous drug use who presented with respiratory symptoms after failing outpatient treatment for community-acquired pneumonia. Further investigations identified multiple lung lesions with early cavitation, concerning for septic pulmonary embolism on computerized tomography scan, positive blood cultures with methicillin-susceptible staphylococcus aureus, and isolated vegetation of the pulmonic valve on transthoracic echocardiography...
2016: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/27799408/congenital-valvular-defects-associated-with-deleterious-mutations-in-the-pld1-gene
#18
Asaf Ta-Shma, Kai Zhang, Ekaterina Salimova, Alma Zernecke, Daniel Sieiro-Mosti, David Stegner, Milena Furtado, Avraham Shaag, Zeev Perles, Bernhard Nieswandt, Azaria J J T Rein, Nadia Rosenthal, Aaron M Neiman, Orly Elpeleg
BACKGROUND: The underlying molecular aetiology of congenital heart defects is largely unknown. The aim of this study was to explore the genetic basis of non-syndromic severe congenital valve malformations in two unrelated families. METHODS: Whole-exome analysis was used to identify the mutations in five patients who suffered from severe valvular malformations involving the pulmonic, tricuspid and mitral valves. The significance of the findings was assessed by studying sporulation of yeast carrying a homologous Phospholipase D (PLD1) mutation, in situ hybridisation in chick embryo and echocardiography and histological examination of hearts of PLD1 knockout mice...
April 2017: Journal of Medical Genetics
https://www.readbyqxmd.com/read/27787211/tranmission-pattern-differences-of-miracidia-and-cercariae-larval-stages-of-digenetic-trematode-parasites
#19
Michael R Zimmermann, Kyle E Luth, Gerald W Esch
Digenetic trematodes have complex life cycles involving multiple hosts and free-living larval stages. Some species have 2 lar-val stages that infect snails, with miracidia and cercariae using these molluscs as first and second intermediate hosts, respec-tively. Although both larval stages may infect the same snail species, this is accomplished using different chemical cues and may be influenced by different biotic and abiotic factors. Significant differences in the infection patterns of these parasitic stages regarding host size and density were observed in 2 separate field studies...
December 1, 2016: Acta Parasitologica
https://www.readbyqxmd.com/read/27763634/phenotypic-predictors-and-final-diagnoses-in-patients-referred-for-rasopathy-testing-by-targeted-next-generation-sequencing
#20
Elizabeth J Bhoj, Zhenming Yu, Qiaoning Guan, Rebecca Ahrens-Nicklas, Kajia Cao, Minjie Luo, Tanya Tischler, Matthew A Deardorff, Elaine Zackai, Avni B Santani
INTRODUCTION: RASopathies include disorders generally characterized by developmental delay, specific heart defects, short stature, cardiac hypertrophy, and facial dysmorphisms. Next-generation sequencing (NGS)-based panels have widespread acceptance as a diagnostic tool for RASopathies. MATERIALS AND METHODS: The first 126 patients evaluated by clinical examination and the NGS RASopathy panel at the Children's Hospital of Philadelphia were enrolled. We calculated diagnosis rate, correlated reported clinical findings with positive or negative test results, and identified final molecular diagnoses in 28/96 patients who tested negative for RASopathies...
October 20, 2016: Genetics in Medicine: Official Journal of the American College of Medical Genetics
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