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https://www.readbyqxmd.com/read/28214372/canonical-and-cellular-pathways-timing-gamete-release-in-acropora-digitifera-okinawa-japan
#1
Y Rosenberg, T Doniger, S Harii, F Sinniger, O Levy
Natural light cycles are important for synchronizing behavioral and physiological rhythms over varying time-periods in both plants and animals. An endogenous clock, regulated by positive and negative elements, interacting in feedback loops, control these rhythms. Many corals exhibit diel cycles of polyp expansion and contraction entrained by solar light patterns and monthly cycles of spawning or planulation that correspond to nocturnal lunar light cycles. However, despite considerable interest in studies of coral reproduction, there is currently not enough molecular information about the cellular pathways involved with synchronizing spawning/planulation in broadcast spawners and brooders...
February 18, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28212706/sclerostin-antibody-inhibits-skeletal-deterioration-in-mice-exposed-to-partial-weight-bearing
#2
J M Spatz, R Ellman, A M Cloutier, L Louis, M van Vliet, D Dwyer, M Stolina, H Z Ke, M L Bouxsein
Whereas much is known regarding the musculoskeletal responses to full unloading, little is known about the physiological effects and response to pharmacological agents in partial unloading (e.g. Moon and Mars) environments. To address this, we used a previously developed ground-based model of partial weight-bearing (PWB) that allows chronic exposure to reduced weight-bearing in mice to determine the effects of murine sclerostin antibody (SclAbII) on bone microstructure and strength across different levels of mechanical unloading...
February 2017: Life Sciences in Space Research
https://www.readbyqxmd.com/read/28195203/reproductive-strategies-of-the-coral-turbinaria-reniformis-in-the-northern-gulf-of-aqaba-red-sea
#3
Hanna Rapuano, Itzchak Brickner, Tom Shlesinger, Efrat Meroz-Fine, Raz Tamir, Yossi Loya
Here we describe for the first time the reproductive biology of the scleractinian coral Turbinaria reniformis studied during three years at the coral reefs of Eilat and Aqaba. We also investigated the possibility of sex change in individually tagged colonies followed over a period of 12 years. T. reniformis was found to be a stable gonochorist (no detected sex change) that reproduces by broadcast spawning 5-6 nights after the full moon of June and July. Spawning was highly synchronized between individuals in the field and in the lab...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28165425/g-channel-restoration-for-rwb-cfa-with-double-exposed-w-channel
#4
Chulhee Park, Ki Sun Song, Moon Gi Kang
In this paper, we propose a green (G)-channel restoration for a red-white-blue (RWB) color filter array (CFA) image sensor using the dual sampling technique. By using white (W) pixels instead of G pixels, the RWB CFA provides high-sensitivity imaging and an improved signal-to-noise ratio compared to the Bayer CFA. However, owing to this high sensitivity, the W pixel values become rapidly over-saturated before the red-blue (RB) pixel values reach the appropriate levels. Because the missing G color information included in the W channel cannot be restored with a saturated W, multiple captures with dual sampling are necessary to solve this early W-pixel saturation problem...
February 5, 2017: Sensors
https://www.readbyqxmd.com/read/28158155/comparison-of-cervical-sagittal-alignment-and-kinematics-after-posterior-full-endoscopic-cervical-foraminotomy-and-discectomy-according-to-preoperative-cervical-alignment
#5
Samuel Won, Chi Heon Kim, Chun Kee Chung, Yunhee Choi, Sung Bae Park, Jung Hyeon Moon, Won Heo, Sung-Mi Kim
BACKGROUND: The progression of cervical kyphosis due to injury to the facet joints and musculature is a major concern for posterior foraminotomy especially for patients with cervical lordosis of less than 10°. However, cervical hypo-lordosis (cervical lordosis < 10°) may be improved with the alleviation of pain and muscle spasms, which corresponds with the disappearance of a positive Spurling's test. When surgery is necessary, the spontaneous recovery of cervical curvature may be minimally offset using minimally invasive surgical techniques, such as posterior percutaneous endoscopic cervical foraminotomy (P-PECF)...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28141890/transcriptome-dynamics-over-a-lunar-month-in-a-broadcast-spawning-acroporid-coral
#6
Matthew J Oldach, Matthew Workentine, Mikhail V Matz, T-Y Fan, Peter D Vize
On one night per year, at a specific point in the lunar cycle, one of the most extraordinary reproductive events on the planet unfolds as hundreds of millions of broadcast spawning corals release their trillions of gametes into the waters of the tropical seas. Each species spawns on a specific night within the lunar cycle, typically from full moon to third quarter moon, and in a specific time window after sunset. This accuracy is essential to achieve efficient fertilization in the vastness of the oceans. In this report we use transcriptome sequencing at noon and midnight across an entire lunar cycle to explore how Acroporid corals interpret lunar signals...
January 31, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28120959/toward-full-simulation-of-the-electrochemical-oxygen-reduction-reaction-on-pt-using-first-principles-and-kinetic-calculations
#7
Tamio Ikeshoji, Minoru Otani
Present fuel cells must increase the activity of the oxygen reduction reaction (ORR) on platinum (or Pt alloy) electrodes. Detailed simulation analyses can direct future investigations by providing a better understanding of the ORR. We adopted a density functional theory (DFT)-based, first-principles molecular dynamics simulation for the elementary steps of the electrochemical ORR on Pt(111). The two-step process involves successive protonation of O and OH, which are adsorbed on Pt. The relevant redox potentials were estimated by changing the coverage of OH(ad) and O(ad)...
January 25, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28096517/the-nucleoside-analog-clitocine-is-a-potent-and-efficacious-readthrough-agent
#8
Westley J Friesen, Christopher R Trotta, Yuki Tomizawa, Jin Zhuo, Briana Johnson, Jairo Sierra, Bijoyita Roy, Marla Weetall, Jean Hedrick, Josephine Sheedy, James Takasugi, Young-Choon Moon, Suresh Babu, Ramil Baiazitov, John D Leszyk, Thomas W Davis, Joseph M Colacino, Stuart W Peltz, Ellen M Welch
Nonsense mutations resulting in a premature stop codon in an open reading frame occur in critical tumor suppressor genes in a large number of the most common forms of cancers and are known to cause or contribute to the progression of disease. Low molecular weight compounds that induce readthrough of nonsense mutations offer a new means of treating patients with genetic disorders or cancers resulting from nonsense mutations. We have identified the nucleoside analog clitocine as a potent and efficacious suppressor of nonsense mutations...
April 2017: RNA
https://www.readbyqxmd.com/read/28053633/addition-of-digital-breast-tomosynthesis-to-full-field-digital-mammography-in-the-diagnostic-setting-additional-value-and-cancer-detectability
#9
Mirinae Seo, Jung Min Chang, Sun Ah Kim, Won Hwa Kim, Ji He Lim, Su Hyun Lee, Min Sun Bae, Hye Ryoung Koo, Nariya Cho, Woo Kyung Moon
PURPOSE: The purpose of this study was to assess the value of adding digital breast tomosynthesis (DBT) to full-field digital mammography (FFDM) in the diagnostic workup of breast cancer and to determine which lesion variables affect cancer detectability in the combined modality. METHODS: Between March and May 2012, paired FFDM and DBT images were obtained from 203 women as part of a diagnostic workup for breast cancer. Images from FFDM alone, DBT alone, and DBT combined with FFDM were reviewed in separate sessions by six blinded readers...
December 2016: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28038812/hopelessness-among-adults-with-congenital-heart-disease-cause-for-despair-or-hope
#10
Bahareh Eslami, Adrienne H Kovacs, Philip Moons, Kyomars Abbasi, Jamie L Jackson
BACKGROUND: Adults with congenital heart disease (CHD) face unique life courses and challenges that may negatively influence their psychological functioning. The aims of this study were to (1) examine the level of hopelessness among adults with CHD in comparison with non-CHD participants and (2) identify correlates of elevated hopelessness among adults with CHD. METHODS: We enrolled 347 patients with CHD (18-64years, 52.2% female) and 353 matched (by sex/age) non-CHD persons in this cross-sectional study...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28008358/impact-of-microvascular-obstruction-on-semiautomated-techniques-for-quantifying-acute-and-chronic-myocardial-infarction-by-cardiovascular-magnetic-resonance
#11
Heerajnarain Bulluck, Stefania Rosmini, Amna Abdel-Gadir, Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Shane Weinmann, Alex Sirker, Anna S Herrey, Charlotte Manisty, James C Moon, Derek J Hausenloy
AIMS: The four most promising semiautomated techniques (5-SD, 6-SD, Otsu and the full width half maximum (FWHM)) were compared in paired acute and follow-up cardiovascular magnetic resonance (CMR), taking into account the impact of microvascular obstruction (MVO) and using automated extracellular volume fraction (ECV) maps for reference. Furthermore, their performances on the acute scan were compared against manual myocardial infarct (MI) size to predict adverse left ventricular (LV) remodelling (≥20% increase in end-diastolic volume)...
2016: Open Heart
https://www.readbyqxmd.com/read/28008162/endoscopic-approach-for-major-complications-of-bariatric-surgery
#12
Moon Kyung Joo
As lifestyle and diet patterns have become westernized in East Asia, the prevalence of obesity has rapidly increased. Bariatric surgeries, such as Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), and laparoscopic adjustable gastric banding (LAGB), are considered the first-line treatment option in patients with severe obesity. However, postoperative complications have increased and the proper management of these complications, including the use of endoscopic procedures, has become important. The most serious complications, such as leaks and fistulas, can be treated with endoscopic stent placement and injection of fibrin glue, and a novel full-thickness closure over-the-scope clip (OTSC) has been used for treatment of postoperative leaks...
January 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28002650/discovery-of-short-linear-motif-mediated-interactions-through-phage-display-of-intrinsically-disordered-regions-of-the-human-proteome
#13
Norman E Davey, Moon-Hyeong Seo, Vikash Kumar Yadav, Jouhyun Jeon, Satra Nim, Izabella Krystkowiak, Cecilia Blikstad, Debbie Dong, Natalia Markova, Philip M Kim, Ylva Ivarsson
The intrinsically disordered regions of eukaryotic proteomes are enriched in short linear motifs (SLiMs), which are of crucial relevance for cellular signaling and protein regulation; many mediate interactions by providing binding sites for peptide-binding domains. The vast majority of SLiMs remain to be discovered highlighting the need for experimental methods for their large-scale identification. We present a novel proteomic peptide phage display (ProP-PD) library that displays peptides representing the disordered regions of the human proteome, allowing direct large-scale interrogation of most potential binding SLiMs in the proteome...
December 21, 2016: FEBS Journal
https://www.readbyqxmd.com/read/27995759/hydrogel-functionalized-janus-membrane-for-skin-regeneration
#14
Young-Hyeon An, Seung Jung Yu, In Seon Kim, Su-Hwan Kim, Jeong-Mi Moon, Seunghyun L Kim, Young Hwan Choi, Joon Sig Choi, Sung Gap Im, Kyung Eun Lee, Nathaniel S Hwang
In this study, a hydrogel functionalized Janus membrane is developed and its capacity is examined as a wound dressing biomaterial. A hydrophobic fluoropolymer, poly(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl methacrylate) (PHFDMA), is uniformly coated onto macroporous polyester membrane through initiated chemical vapor deposition process on both sides. PHFDMA-coated macroporous membrane exhibits antibacterial property, allows air permeation, and inhibits water penetration. Janus membrane property is obtained by exposing one side of PHFDMA coated membrane with 1 m KOH solution, which allows PHFDMA cleavage resulting in carboxylic acid residue...
December 20, 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/27940294/long-term-performance-and-bacterial-community-dynamics-in-biocovers-for-mitigating-methane-and-malodorous-gases
#15
Eun-Hee Lee, Kyung-Eun Moon, Kyung-Suk Cho
The long-term performance of lab-scale biocovers for the simulation of engineered landfill cover soils was evaluated. Methane (CH4), trimethylamine (TMA), and dimethyl sulfide (DMS) were introduced into the biocovers as landfill gases for 134 days and the removal performance was evaluated. The biocover systems were capable of simultaneously removing methane, TMA, and DMS. Methane was mostly eliminated in the top layer of the systems, while TMA and DMS were removed in the bottom layer. Overall, the methane removal capacity and efficiency were 224...
January 20, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/27928860/physical-activity-subjective-sleep-quality-and-time-in-bed-do-not-vary-by-moon-phase-in-german-adolescents
#16
Maia P Smith, Marie Standl, Holger Schulz, Joachim Heinrich
Lunar periodicity in human biology and behaviour, particularly sleep, has been reported. However, estimated relationships vary in direction (more or less sleep with full moon) if they exist at all, and studies tend to be so small that there is potential for confounding by weekly or monthly cycles. Lunar variation in physical activity has been posited as a driver of this relationship, but is likewise not well studied. We explore the association between lunar cycle, sleep and physical activity in a population-based sample of 1411 Germans age 14-17 years (46% male)...
December 8, 2016: Journal of Sleep Research
https://www.readbyqxmd.com/read/27912006/cascading-effects-of-predation-risk-determine-how-marine-predators-become-terrestrial-prey-on-an-oceanic-island
#17
Sarah K Thomsen, David J Green
Apex predators can suppress the foraging activity of mesopredators, which may then result in cascading benefits for the prey of those mesopredators. We studied the interactions between a top predator, the Barn Owl (Tyto alba), and their primary prey, an island endemic deer mouse (Peromyscus maniculatus elusus), which in turn consumes the eggs of seabirds nesting on Santa Barbara Island in California. Scripps's Murrelets (Synthliboramphus scrippsi), a threatened nocturnal seabird, arrive annually to breed on this island, and whose first egg is particularly vulnerable to predation by mice...
December 2016: Ecology
https://www.readbyqxmd.com/read/27904731/clinical-usefulness-of-long-term-application-of-fentanyl-matrix-in-chronic-non-cancer-pain-improvement-of-pain-and-physical-and-emotional-functions
#18
Jaewon Lee, Joon Shik Yoon, Jae Hyup Lee, So-Hak Chung, Kyu-Yeol Lee, Young Yul Kim, Jong Moon Kim, Min Ho Kong, Ung Gu Kang, Ye-Soo Park
BACKGROUND: Opioids are recently recommended for those who do not gain adequate pain relief from the use of acetaminophen or nonsteroidal anti-inflammatory drugs. Medical opioids are administered in various routes, and transdermal opioid products that can make up for the weaknesses of the oral or intravenous products have been developed. This study is to evaluate the clinical usefulness of fentanyl matrix in terms of the long-term improvement in pain and physical and mental functions...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27895241/secular-pattern-of-aneurismal-rupture-with-the-lunar-cycle-and-season
#19
Jillian C Banfield, Mohamed Abdolell, Jai S Shankar
Background The lunar cycle and seasons may be associated with rates of rupture of intracranial aneurysms, but the literature is mixed. Studies of the association between the lunar cycle and rates of aneurysm rupture used the eight qualitative moon phases. The purpose of this study was to assess any association of aneurysm rupture with the lunar cycle and with the season. Materials and methods We retrospectively reviewed all cases of subarachnoid haemorrhage secondary to ruptured intracranial aneurysm treated with endovascular coiling in our institution over a 10-year period...
February 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/27889485/safety-and-effectiveness-of-anterior-fundoplication-sleeve-gastrectomy-in-patients-with-severe-reflux
#20
Rena C Moon, Andre F Teixeira, Muhammad A Jawad
BACKGROUND: Laparoscopic sleeve gastrectomy has become a popular bariatric surgery in recent years. However, it has been linked to worsening or newly developed gastroesophageal reflux disease (GERD) in the postoperative period. OBJECTIVES: The purpose of this study is to determine the safety and effectiveness of anterior fundoplication sleeve gastrectomy in patients with reflux. SETTING: Academic hospital, United States. METHODS: We prospectively collected data on 31 sleeve gastrectomy patients who concurrently underwent anterior fundoplication between July 2014 and March 2016...
October 17, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
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