keyword
MENU ▼
Read by QxMD icon Read
search

overuse of antibiotics

keyword
https://www.readbyqxmd.com/read/29022964/nocardia-arthritidis-keratitis-case-report-and-review-of-the-literature
#1
Andrew Gieger, Stephen Waller, Joseph Pasternak
INTRODUCTION: Keratitis due to Nocardia infection is not commonly encountered in clinical practice and may therefore be mistaken for fungal or viral keratitis leading to delayed treatment and increased risk of permanent visual impairment. CASE: An otherwise healthy 27 years old Caucasian Active Duty military member presented to the clinic with three days of light sensitivity and irritation of his right eye. He carried a history of PRK in both eyes six years prior and admitted to recent contact lens overuse...
January 2017: Nepalese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28992328/what-parents-think-about-the-risks-and-benefits-of-antibiotics-for-their-child-s-acute-respiratory-tract-infection
#2
Julia E Szymczak, Sarah B Klieger, Matthew Miller, Alexander G Fiks, Jeffrey S Gerber
Background: Parental pressure is often cited as a reason for why pediatricians overuse antibiotics for children with acute respiratory tract infection (ARTI). We sought to capture parent perceptions of antibiotics at the time of their child's presentation with an ARTI. Methods: We conducted semistructured interviews with parents of children who presented with ARTI symptoms to 1 of 4 diverse practices in a large hospital-affiliated network of pediatric primary care practices...
September 14, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28979121/optimization-and-integration-of-nanosilver-on-polycaprolactone-nanofibrous-mesh-for-bacterial-inhibition-and-wound-healing-in-vitro-and-in-vivo
#3
Menglong Liu, Gaoxing Luo, Ying Wang, Weifeng He, Tengfei Liu, Daijun Zhou, Xiaohong Hu, Malcolm Xing, Jun Wu
Bacterial infection is a major hurdle to wound healing, and the overuse of antibiotics have led to global issue, such as emergence of multidrug-resistant bacteria, even "super bacteria". On the contrary, nanosilver (NS) can kill bacteria without causing resistant bacterial strains. In this study, NS was simply generated in situ on the polycaprolactone (PCL) nanofibrous mesh using an environmentally benign and mussel-inspired dopamine (DA). Scanning electron microscopy showed that NS uniformly formed on the nanofibers of PCL mesh...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28978750/rapid-pathogen-specific-phenotypic-antibiotic-susceptibility-testing-using-digital-lamp-quantification-in-clinical-samples
#4
Nathan G Schoepp, Travis S Schlappi, Matthew S Curtis, Slava S Butkovich, Shelley Miller, Romney M Humphries, Rustem F Ismagilov
Rapid antimicrobial susceptibility testing (AST) is urgently needed for informing treatment decisions and preventing the spread of antimicrobial resistance resulting from the misuse and overuse of antibiotics. To date, no phenotypic AST exists that can be performed within a single patient visit (30 min) directly from clinical samples. We show that AST results can be obtained by using digital nucleic acid quantification to measure the phenotypic response of Escherichia coli present within clinical urine samples exposed to an antibiotic for 15 min...
October 4, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28973636/influence-of-point-of-care-c-reactive-protein-testing-on-antibiotic-prescription-habits-in-primary-care-in-the-netherlands
#5
Tim J Schuijt, David S Boss, Ruben E A Musson, Ayse Y Demir
Background: Bacterial resistance to antibiotics represents a serious global challenge that is associated with high morbidity and mortality. One of the most important causes of this threat is antibiotic overuse. The Dutch College of General Practitioners (DCGP) recommends the use of point-of-care (POC) testing for C-reactive protein (CRP) in two guidelines ('Acute Cough' and 'Diverticulitis') to achieve a more sensible prescription pattern of antibiotics. Objective: To evaluate the use of POC-CRP testing in light of the DCGP guidelines and the effect of CRP measurements on antibiotic prescription policy in primary care...
September 1, 2017: Family Practice
https://www.readbyqxmd.com/read/28973402/2017-update-on-medical-overuse-a-systematic-review
#6
Daniel J Morgan, Sanket S Dhruva, Eric R Coon, Scott M Wright, Deborah Korenstein
Importance: Overuse of medical care is a well-recognized problem. Objective: To identify and highlight original research articles published in 2016 that are most relevant to understanding medical overuse or strategies to reduce it. Evidence Review: A structured review of English-language articles on PubMed published in 2016 coupled with examination of tables of contents of high-impact journals to identify articles related to medical overuse in adults...
October 2, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28906047/a-systematic-review-to-explore-influences-on-parental-attitudes-towards-antibiotic-prescribing-in-children
#7
REVIEW
Helen Bosley, Catherine Henshall, Jane V Appleton, Debra Jackson
AIM: To understand the factors influencing parental attitudes towards antibiotic prescribing. BACKGROUND: Overuse of antibiotics and inappropriate prescribing has resulted in rapid development of antimicrobial resistance (AMR), and is significant global threat to patient safety. In Primary Care settings, substantial numbers of antibiotics are prescribed for young children, despite viral nature of illness for which antibiotics are ineffective. Parents, play a vital role in decision making regarding accessing healthcare services and requesting treatment for their children...
September 14, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28894729/procalcitonin-for-diagnostics-and-treatment-decisions-in-pediatric-lower-respiratory-tract-infections
#8
Philipp Baumann, Gurli Baer, Jessica Bonhoeffer, Aline Fuchs, Verena Gotta, Ulrich Heininger, Nicole Ritz, Gabor Szinnai, Jan Bonhoeffer
Mortality and morbidity remain high in pediatric lower respiratory tract infections (LRTIs) despite progress in research and implementation of global diagnostic and treatment strategies in the last decade. Still, 120 million annual episodes of pneumonia affect children younger than 5 years each year leading to 1.3 million fatalities with the major burden of disease carried by low- and middle-income countries (95%). The definition of pneumonia is still challenging. Traditional diagnostic measures (i.e., chest radiographs, C-reactive protein) are unable to distinguish viral and from bacterial etiology...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28890457/healing-animals-in-an-antibiotic-age-veterinary-drugs-and-the-professionalism-crisis-1945-1970
#9
Kendra Smith-Howard
Between 1945 and 1970, the introduction of antibiotics in agriculture forced veterinarians to articulate the boundaries of their professional identity. While veterinarians welcomed the new aid to arrest infectious diseases of livestock, they worried as farmers took animal healing into their own hands without veterinary supervision, and resented the competition from retail outlets that sold the drugs. Veterinary antibiotics also set off heated debates within the field about whether the profession should position itself as preventers or healers of disease, debates that were akin to the kinds of professional discourses among physicians and pharmacists in the same period...
2017: Technology and Culture
https://www.readbyqxmd.com/read/28889650/correlation-of-recommendations-of-treatment-guidelines-and-frequently-prescribed-antibiotics-evaluation-of-their-pharmaceutical-pack-size
#10
Shoma Mukherjee, Nilanjan Saha
There are various factors that contribute to development of antimicrobial resistance. Overuse, inappropriate prescribing and extensive agricultural use of antibiotics are some of the factors which have been identified. Antibiotics are almost always universally packaged by manufacturers in packs that are heavily driven by cost of economies and convenience rather than by any scientific basis or duration of therapy. So, in the present study, the correlation of the treatment guidelines with the choice of antibiotics and whether packing size contributes to left-over dosing units when used according to guideline recommendations were assessed...
September 10, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28887201/reactive-oxygen-therapy-a-novel-antimicrobial
#11
REVIEW
Matthew Dryden
The main solution to the global antibiotic resistance crisis is reducing the volume of antibiotic use in medicine, agriculture and the environment. However there is also a pressing need for novel antimicrobials. Despite much rhetoric, there are few entirely novel agents in development. One such therapy to reach clinical use is an agent using Reactive Oxygen Species (ROS), oxygen radicals, as an antimicrobial mechanism. ROS can be delivered to the site of infection in various formats. ROS is highly antimicrobial against Gram positive and negative bacteria, viruses and fungi...
September 5, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28857444/environmental-vibrios-represent-a-source-of-antagonistic-compounds-that-inhibit-pathogenic-vibrio-cholerae-and-vibrio-parahaemolyticus-strains
#12
David J Burks, Stephen Norris, Kathryn M Kauffman, Abigail Joy, Philip Arevalo, Rajeev K Azad, Hans Wildschutte
With the overuse of antibiotics, many pathogens including Vibrio cholerae and Vibrio parahaemolyticus have evolved multidrug resistance making treatment more difficult. While understanding the mechanisms that underlie pathogenesis is crucial, knowledge of bacterial interactions of V. cholerae and V. parahaemolyticus could provide insight to their susceptibility outside of the human host. Based on previous work showing competition among environmental strains, we predict that marine-derived bacteria should inhibit Vibrio pathogens and may be a source of unique antibiotic compounds...
October 2017: MicrobiologyOpen
https://www.readbyqxmd.com/read/28851505/clostridium-difficile-on-youtube-a-need-for-greater-focus-on-prevention
#13
Corey H Basch, Grace Clarke Hillyer, Philip Garcia, Charles E Basch
The purpose of this study was to describe the content of the most popular YouTube videos related to Clostridium difficile. Across all sources, the kinds of content most likely to be included in the videos was general information, overuse of antibiotics, and symptomatic diarrhea. Health professionals can contribute to existing social media messages related to C. difficile with comprehensive messages that include means for prevention.
August 26, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28851296/design-and-rationale-of-the-procalcitonin-antibiotic-consensus-trial-proact-a-multicenter-randomized-trial-of-procalcitonin-antibiotic-guidance-in-lower-respiratory-tract-infection
#14
David T Huang, Derek C Angus, Chung-Chou H Chang, Yohei Doi, Michael J Fine, John A Kellum, Octavia M Peck-Palmer, Francis Pike, Lisa A Weissfeld, Jonathan Yabes, Donald M Yealy
BACKGROUND: Overuse of antibiotics is a major public health problem, contributing to growing antibiotic resistance. Procalcitonin has been reported to be commonly elevated in bacterial, but not viral infection. Multiple European trials found procalcitonin-guided care reduced antibiotic use in lower respiratory tract infection, with no apparent harm. However, applicability to US practice is limited due to trial design features impractical in the US, between-country differences, and residual safety concerns...
August 29, 2017: BMC Emergency Medicine
https://www.readbyqxmd.com/read/28812924/susceptibility-testing-and-reporting-of-new-antibiotics-with-a-focus-on-tedizolid-an-international-working-group-report
#15
Mark H Wilcox, Natalia Dmitrieva, Ana Cristina Gales, Irina Petukhova, Suleiman Al-Obeid, Flavia Rossi, Joseph M Blondeau
Inappropriate use and overuse of antibiotics are among the most important factors in resistance development, and effective antibiotic stewardship measures are needed to optimize outcomes. Selection of appropriate antimicrobials relies on accurate and timely antimicrobial susceptibility testing. However, the availability of clinical breakpoints and in vitro susceptibility testing often lags behind regulatory approval by several years for new antimicrobials. A Working Group of clinical/medical microbiologists from Brazil, Canada, Mexico, Saudi Arabia, Russia and the UK recently examined issues surrounding antimicrobial susceptibility testing for novel antibiotics...
August 16, 2017: Future Microbiology
https://www.readbyqxmd.com/read/28810609/value-of-serum-mycoplasma-pneumoniae-immunoglobulin-in-the-diagnosis-of-mycoplasma-related-pneumonia-in-newborns
#16
Yan Dong, Wei Lv, Zhen Lin
Mycoplasma pneumoniae (M. pneumoniae) is an important pathogen of neonatal acquired pneumonia in newborns. Rapid and accurate diagnosis of M. pneumoniae infection is critical because timely antibiotic therapy can reduce drug overuse and prevent the development of bacterial resistance. Anti-M. pneumoniae immunoglobulin M (IgM) is an indicator of early infection that can persist for several months. Studies have shown that anti-M. pneumoniae IgA in adults is a reliable indicator of early M. pneumoniae infection...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28768551/feed-additive-probiotics-accelerate-yet-antibiotics-delay-intestinal-microbiota-maturation-in-broiler-chicken
#17
Pengfei Gao, Chen Ma, Zheng Sun, Lifeng Wang, Shi Huang, Xiaoquan Su, Jian Xu, Heping Zhang
BACKGROUND: Reducing antibiotics overuse in animal agriculture is one key in combat against the spread of antibiotic resistance. Probiotics are a potential replacement of antibiotics in animal feed; however, it is not clear whether and how probiotics and antibiotics differ in impact on physiology and microbial ecology of host animals. RESULTS: Host phenotype and fecal microbiota of broilers with either antibiotics or probiotics as feed additive were simultaneously sampled at four time points from birth to slaughter and then compared...
August 3, 2017: Microbiome
https://www.readbyqxmd.com/read/28763554/does-this-child-have-pneumonia-the-rational-clinical-examination-systematic-review
#18
REVIEW
Sonal N Shah, Richard G Bachur, David L Simel, Mark I Neuman
Importance: Pneumonia is a leading cause of morbidity and mortality in children. It is important to identify the clinical symptoms and physical examination findings associated with pneumonia to improve timely diagnosis, prevent significant morbidity, and limit antibiotic overuse. Objective: To systematically review the accuracy of symptoms and physical examination findings in identifying children with radiographic pneumonia. Data Sources and Study Selection: MEDLINE and Embase (1956 to May 2017) were searched, along with reference lists from retrieved articles, to identify diagnostic studies of pediatric pneumonia across a broad age range that had to include children younger than age 5 years (although some studies enrolled children up to age 19 years); 3644 unique articles were identified, of which 23 met inclusion criteria...
August 1, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28760143/decision-support-during-electronic-prescription-to-stem-antibiotic-overuse-for-acute-respiratory-infections-a-long-term-quasi-experimental-study
#19
Jeneen Gifford, Elisabeth Vaeth, Katherine Richards, Tariq Siddiqui, Christine Gill, Lucy Wilson, Sylvain DeLisle
BACKGROUND: Interventions to support decision-making can reduce inappropriate antibiotic use for acute respiratory infections (ARI), but they may not be sustainable. The objective of the study is to evaluate the long-term effectiveness of a clinical decision-support system (CDSS) interposed at the time of electronic (e-) prescriptions for selected antibiotics. METHODS: This is a retrospective, observational intervention study, conducted within a large, statewide Veterans Affairs health system...
July 31, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28758294/periodontitis-facts-fallacies-and-the-future
#20
REVIEW
Jørgen Slots
This volume of Periodontology 2000 represents the 25th anniversary of the Journal, and uses the occasion to assess important advancements in periodontology over the past quarter-century as well as the hurdles that remain. Periodontitis is defined by pathologic loss of the periodontal ligament and alveolar bone. The disease involves complex dynamic interactions among active herpesviruses, specific bacterial pathogens and destructive immune responses. Periodontal diagnostics is currently based on clinical rather than etiologic criteria, and provides limited therapeutic guidance...
October 2017: Periodontology 2000
keyword
keyword
98820
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"