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Endashaw Omer, Archana Kedar, Harsha S Nagarajarao, Yana Nikitina, Vetta Vedanarayanan, Charu Subramony, Christopher J Lahr, Thomas L Abell
BACKGROUND AND AIMS: Cajal cells serve as the pacemaker cells of the gastrointestinal tract and regulates peristalsis. On the baisis of that fact, it has been hypothesized that a decrease in Cajal cells can lead to gastroparesis and other motility issues. Treatment with medications has a limited efficacy and most resort to gastric electrical stimulation (GES) devices for symptomatic relief. We believe that the number of Cajal cells present is directly proportional to symptomatic relief with GES...
April 18, 2018: Journal of Clinical Gastroenterology
Lönroth, Abrahamsson
Gastric Electrical Stimulation (GES) with a fully implantable device including two electrodes to the gastric wall has proven to be an effective treatment of symptoms in patients with gastroparesis and therapy of refractory nausea and vomiting. Stimulation is given continuously with 12 imp/min at 5 mA. Multicentre studies have shown effectiveness in most patients with diabetic and idiopathic gastroperesis but results are promising also for postsurgical gastroparesis. The long-term clinical outcome seems to be similar for the two implantation techniques, laparoscopy and open surgery, but the postoperative hospital stay is shorter after laparoscopy...
December 2004: Minimally Invasive Therapy & Allied Technologies: MITAT
Salaheddin Tomi, Maria Płazińska, Edyta Zagórowicz, Bartłomiej Ziółkowski, Jacek Muszynski
OBJECTIVE: 1. To find out the prevalence of gastroperesis and of accelerated gastric emptying in long-standing and recently diagnosed diabetic patients. 2. and to determine the relationship between the percentage of gastric retention of the test meal to the gastric symptoms, degree of metabolic control, cardiovascular autonomic neuropathy, and late diabetic complication. RESEARCH DESIGN AND METHODS: We studied the gastric emptying of technetium labeled digestible solid test meal in 81 diabetic patients (51 long-standing and 30 recently diagnosed diabetic patients) and in 44 healthy controls...
September 2002: Polskie Archiwum Medycyny Wewnętrznej
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