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TGF beta AND Naringin

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https://www.readbyqxmd.com/read/24880026/naringin-a-flavanone-glycoside-promotes-angiogenesis-and-inhibits-endothelial-apoptosis-through-modulation-of-inflammatory-and-growth-factor-expression-in-diabetic-foot-ulcer-in-rats
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Amit D Kandhare, Pinaki Ghosh, Subhash L Bodhankar
Chronic, unhealed diabetic foot ulcer (DFU) is one of the most severe complications of diabetes mellitus (DM). Naringin, a flavanone glycoside antioxidant, was reported to have antidiabetic and anti-apoptotic properties. In the present study DM was induced experimentally by streptozotocin (STZ, 55 mg/kg, i.p.). In surgically introduced wounds on the dorsal surface of the hind paw of rats, the healing potential of naringin was investigated. Rats were treated with naringin (20, 40 and 80 mg/kg, p.o.), insulin (10 IU/kg, s...
August 5, 2014: Chemico-biological Interactions
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