Teresa Valbuena, Marta Reche, Guadalupe Marco, Inmaculada Toboso, Anna Ringauf, Israel J Thuissard-Vasallo, Daniel Lozano-Ojalvo, Mónica Martínez-Blanco, Elena Molina
Oral food challenge (OFC) remains the gold standard for the diagnosis of food allergies. However, this test is not without risks, given that severe allergic reactions can be triggered while it is conducted. The purpose of this study is to identify potential demographic variables, clinical characteristics of the patients and biomarkers that may be associated with severe reactions during the hazelnut oral challenge test. The sample included 22 children allergic to hazelnut who underwent a tree nut skin prick test (SPT), specific IgE (sIgE) to hazelnut, component-resolved diagnosis (CRD) with different hazelnut allergens (Cor a 1, Cor a 8, Cor a 9, Cor a 11, Cor a 14), and a single-blind placebo-controlled challenge with hazelnut...
October 15, 2021: Foods (Basel, Switzerland)