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hpv cervical smear

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https://www.readbyqxmd.com/read/28512628/dysplasia-of-granulocytes-in-a-patient-with-hpv-disease-recurrent-infections-and-b-lymphopenia-a-novel-variant-of-whim-syndrome
#1
Giusella M F Moscato, Erica Giacobbi, Lucia Anemona, Silvia Di Cesare, Gigliola Di Matteo, Massimo Andreoni, Alessandro Mauriello, Viviana Moschese
WHIM syndrome is a condition in which affected persons have chronic peripheral neutropenia, lymphopenia, abnormal susceptibility to human papilloma virus infection, and myelokathexis. Myelokathexis refers to the retention of mature neutrophils in the bone marrow (BM), which accounts for degenerative changes and hypersegmentation. Most patients present heterozygous autosomal dominant mutations of the gene encoding CXCR4. Consequently, aberrant CXCL12/CXCR4 signaling impairs the receptor downregulation causing hyperactivation (gain-of-function) that affects BM homing for myelopoiesis and lymphopoiesis and the release of neutrophils in the bloodstream...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28481782/oral-human-papillomavirus-in-women-with-high-grade-cervical-intraepithelial-neoplasia
#2
Linn Woelber, Julia Breuer, Thomas Meyer, Eik Vettorazzi, Katharina Prieske, Inga Bohlmann, Chia-Jung Busch, Ingo Teudt, Oliver Brummer, Volkmar Mueller, Barbara Schmalfeldt, Donata Grimm
OBJECTIVE: This study was designed to investigate the co-prevalence of cervical and oropharyngeal human papillomavirus (HPV) infection in patients with HPV-related high-grade disease of the uterine cervix (high-grade squamous intraepithelial lesion [HSIL]). MATERIALS AND METHODS: In a prospective cohort study, women with abnormal cervical cytology admitted to our colposcopy units received HPV testing of the uterine cervix and the oropharynx via smear. From a subset of patients, oral lavage was collected to compare detection rates of HPV DNA between lavage and swab...
May 5, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28479075/-pap-smear-before-25-years-old
#3
A Rousselin, L Dion, A Racin, V Lavoué, J Levêque, K Nyangoh Timoh
OBJECTIVES: Current French recommendations advocate cervical-vaginal screening for cervical cancer from age 25 whereas earlier screening is mostly found in current clinical practice although its consequences are not well understood. METHODS: A literature review using the MedLine database on the natural history of HPV infections, cytological screening, management of cytological and histological anomalies in adolescents and young women. RESULTS: The adolescent and young woman have some characteristics that distinguish them from adult women: a high prevalence of HPV infections (making the use of the HPV test unprofitable), accompanied by a higher clearance; frequency of minor cytological abnormalities (for which a cytological surveillance without colposcopy is sufficient) and low-grade histological lesions of low grade the usual prognosis of which is complete recovery; and rarity of CIN3 lesions and absence of invasive lesions, allowing no treatment in patients with CIN2 lesions and compliant to cytological and colposcopic surveillance...
May 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/28454338/ellagic-acid-and-annona-muricata-in-the-chemoprevention-of-hpv-related-pre-neoplastic-lesions-of-the-cervix
#4
Giulia Morosetti, Anna Angela Criscuolo, Flavia Santi, Carlo Federico Perno, Emilio Piccione, Marco Ciotti
Ellagic acid is a phenolic compound naturally present in nuts and berries. Several studies have demonstrated that this bioactive compound has antioxidant, chemopreventive and antiviral activity. Annona muricata is a type of fruit tree with a long history of traditional use. A number of properties have been attributed to different parts of the plant, including anticancer and antioxidant activities. In the current study, a complex based on ellagic acid, Annona Muricata and antioxidant factors (an ellagic acid complex) was administered to a group of human papilloma virus (HPV) infected women with and without cervical lesions, for 12 months...
March 2017: Oncology Letters
https://www.readbyqxmd.com/read/28453530/intracellular-signaling-entropy-can-be-a-biomarker-for-predicting-the-development-of-cervical-intraepithelial-neoplasia
#5
Masakazu Sato, Kei Kawana, Katsuyuki Adachi, Asaha Fujimoto, Mitsuyo Yoshida, Hiroe Nakamura, Haruka Nishida, Tomoko Inoue, Ayumi Taguchi, Juri Ogishima, Satoko Eguchi, Aki Yamashita, Kensuke Tomio, Osamu Wada-Hiraike, Katsutoshi Oda, Takeshi Nagamatsu, Yutaka Osuga, Tomoyuki Fujii
While the mortality rates for cervical cancer have been drastically reduced after the introduction of the Pap smear test, it still is one of the leading causes of death in women worldwide. Additionally, studies that appropriately evaluate the risk of developing cervical lesions are needed. Therefore, we investigated whether intracellular signaling entropy, which is measured with microarray data, could be useful for predicting the risks of developing cervical lesions. We used three datasets, GSE63514 (histology), GSE27678 (cytology) and GSE75132 (cytology, a prospective study)...
2017: PloS One
https://www.readbyqxmd.com/read/28440976/diagnostic-value-of-the-caretm-hpv-test-in-screening-for-cervical-intraepithelial-neoplasia-grade-2-or-worse
#6
Mojgan Karimi Zarchi, Effat Heydari, Afsarolsadat Tabatabaie, Mansour Moghimi, Wesam Kooti
Background: Cervical cancer is the fourth leading cause of cancer death in women worldwide. Persistent infection with a high risk human papillomavirus (HR-HPV) is the main etiological factor, so that early early detection of HR-HPV is very important. The aim of this study was to investigate the efficacy of CareTM HPV, a new method, as compared with Pap smear, PCR, and biopsy for screening purposes. Material and Method: In this cross-sectional study, 200 sexually active women aging from 25-50 years referred to the oncology clinic of Shahid Sodoughi Yazd Hospital in 2015 with a variety of cervix epithelial lesions or a need for colposcopy were enrolled...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28422558/understanding-transgender-men-s-experiences-with-and-preferences-for-cervical-cancer-screening-a-rapid-assessment-survey
#7
Julia Seay, Atticus Ranck, Roy Weiss, Christopher Salgado, Lydia Fein, Erin Kobetz
PURPOSE: Transgender men are less likely than cisgender women to receive cervical cancer screening. The purpose of the current study was to understand experiences with and preferences for cervical cancer screening among transgender men. METHODS: Ninety-one transgender men ages 21-63 completed the survey. The survey evaluated experiences with and preferences for screening, including opinions regarding human papillomavirus (HPV) self-sampling as a primary cervical cancer screening...
April 19, 2017: LGBT Health
https://www.readbyqxmd.com/read/28420907/effectiveness-of-health-education-programme-level-of-knowledge-about-prevention-of-cervical-cancer-among-saudi-female-healthcare-students
#8
Ghadeer Khaled Al-Shaikh, Sadiqa Badar Syed, Amel Ahmed Fayed, Reem Ali Al-Shaikh, Eman Mohammed Al-Mussaed, Farida Habib Khan, Hala Nasser Elmorshedy
OBJECTIVE: To evaluate the effectiveness of health education programme on the knowledge of human papilloma virus among female medical students. METHODS: This quasi-experimental study was conducted in 2014 at the Princess Nourah bint Abulrahman University, Riyadh, Saudi Arabia, and comprised female medical students. An intervention programme was implemented in the form of lectures, videos, posters, etc. on human papillomavirus. SPSS 20 was used for data analysis...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28410118/disparity-in-rates-of-hpv-infection-and-cervical-cancer-in-underserved-us-populations
#9
Asok Ranjan Karuri, Vivek Kumar Kashyap, Murali Mohan Yallapu, Nadeem Zafar, Satish K Kedia, Meena Jaggi, Subhash C Chauhan
There is a higher rate of HPV infection and cervical cancer incidence and mortality in underserved US population who reside in Appalachian mountain region compared to Northern Plains. Social and behavioral factors such as smoking and alcohol consumption are for such a high incidence. However, by and large, the reasons for these discrepancies lie in the reluctance of the underserved population to adopt preventive measures such as prophylactic Human papilloma virus (HPV) vaccines and Pap smear screening that have significantly reduced the incidence and mortality rate of cervical cancer in Caucasian women...
June 1, 2017: Frontiers in Bioscience (Scholar Edition)
https://www.readbyqxmd.com/read/28390162/concordance-of-hpv-dna-in-cervical-dysplasia-or-genital-warts-in-women-and-their-monogamous-long-term-male-partners
#10
Filip Rob, Ruth Tachezy, Tomáš Pichlík, Petr Škapa, Lukáš Rob, Eva Hamšíková, Jana Šmahelová, Jana Hercogová
Transmission of human papillomavirus (HPV) is a premise for development of cervical dysplasia and genital warts. This cross-sectional study assesses concordance of HPV types present in genital warts or cervical dysplasia in women and genital infection of their monogamous male partners in conjunction with seroprevalence of HPV-6,-11,-16 and -18 antibodies. Blood was taken from both women and men, as well a smear of the urogenital area of men. HPV DNA detection in women was done in fixed paraffin embedded tissues under histological control...
April 8, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28380476/vaginal-neoplasia-induced-by-an-unusual-papillomavirus-subtype-in-a-woman-with-inherited-chromosomally-integrated-human-herpesvirus-type-6a
#11
Maxime Pichon, Alexandre Gaymard, Karine Lebail-Carval, Emilie Frobert, Etienne Beaufils, Gautier Chene, Massimo Tommasino, Bruno Lina, Pascal Gaucherand, Agnès Gautheret-Dejean, Pascale Bonnafous, Tarik Gheit, Annie Buenerd, Gery Lamblin, Yahia Mekki
We describe here a case of high-grade vaginal squamous lesion in a 54-year-old woman with a papillomaviruses (HPV) genital infection that developed from a cervical low-grade squamous intraepithelial lesion (SIL) to a high-grade SIL (H-SIL) on cytological examination. A colposcopy exam led to the detection of suspect vaginal lesions with granulomatous infiltrations, which were classified as a Vaginal Intra-Epithelial Neoplasia grade 2 after pathologists' analyses. After a laser vaginal surgery and a loop excision of the transformation zone, the analyses of the anatomical pieces using a near-complete HPV screening panel revealed an HPV-4 infection that was not detected before in cervical smears...
2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/28344962/efficacy-of-loop-electrosurgical-excision-procedure-with-cold-coagulation-for-treating-cervical-intraepithelial-neoplasia-a-two-center-cohort-study
#12
Hee Seung Kim, Jeong Eun Kwon, Jeong Ha Kim, Anna Kim, Na Ra Lee, Miseon Kim, Maria Lee, Dong Hoon Suh, Yong Beom Kim
OBJECTIVE: To evaluate the efficacy of loop electrosurgical excision procedure (LEEP) combined with cold coagulation for treating cervical intraepithelial neoplasia (CIN). METHODS: We reviewed clinic-pathologic data of 498 patients treated with LEEP alone (n=354), and LEEP combined with cold coagulation (n=144) between January 2000 and December 2011. After LEEP, we followed up all patients by using Papanicolaou smear and human papillomavirus (HPV) test, and evaluated abnormal cervical cytology-free interval and high-risk HPV infection-free interval...
March 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28340612/the-singular-epidemiology-of-hpv-infection-among-french-guianese-women-with-normal-cytology
#13
Antoine Adenis, Valentin Dufit, Maylis Douine, Fatiha Najioullah, Vincent Molinie, Dominique Catherine, Odile Kilié, Nadia Thomas, Jean Luc Deshayes, Paul Brousse, Hatem Ben Amor, Remy Pignoux, Gabriel Carles, Claire Grenier, Vincent Lacoste, Raymond Cesaire, Mathieu Nacher
BACKGROUND: In French Guiana, cervical cancer is the second most frequent cancer in females. The objective of the present study was to describe the prevalence of HPV infections in women with normal cervical cytology living in the remote villages of French Guiana. METHODS: Before the study, the study team communicated in the remote villages on the importance of screening. All women from the target population were offered to participate. They signed informed consent during inclusion and then had a concomitant HPV-test and cervical smear...
March 24, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28279257/approaches-for-triaging-women-who-test-positive-for-human-papillomavirus-in-cervical-cancer-screening
#14
Joseph E Tota, James Bentley, Jennifer Blake, François Coutlée, Máire A Duggan, Alex Ferenczy, Eduardo L Franco, Michael Fung-Kee-Fung, Walter Gotlieb, Marie-Hélène Mayrand, Meg McLachlin, Joan Murphy, Gina Ogilvie, Sam Ratnam
Substantial evidence exists to support the introduction of molecular testing for human papillomavirus (HPV) as the primary technology in cervical cancer screening. While HPV testing is much more sensitive than cytology for detection of high-grade precancerous lesions, it is less specific. To improve efficiency, it is therefore recommended that a specific test (like cytology) be used in triaging HPV positive women to colposcopy. A number of studies have been conducted that support the use of cytology alone or in conjunction with HPV genotyping for triage...
May 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28207678/mexican-american-college-men-s-mis-understandings-about-hpv-and-cervical-cancer
#15
Tiffany A Schiffner, Lydia P Buki, Raha F Sabet
Latinas have disproportionally high rates of cervical cancer in part due to their reliance on Latino partners to make sexual health decisions, their limited knowledge about human papillomavirus (HPV), and inconsistent Pap smear screening behaviors. In this qualitative study, we examined the sexual health beliefs of Latino college men regarding HPV. Participants included 6 Mexican American college students from a large Midwestern university. We conducted 18 in-depth individual interviews about men's beliefs, attitudes, and knowledge about HPV...
April 2017: Family & Community Health
https://www.readbyqxmd.com/read/28182076/vaginal-infections-of-albanian-women-infected-with-hpv-and-their-impact-in-intraepithelial-cervical-lesions-evidenced-by-pap-test
#16
Elsa S Kone, Avenir D Balili, Piro D Paparisto, Xheladin R Ceka, Elizana D Petrela
BACKGROUND: Cervical cytology is the best single method for large screening of the population in identifying precancerous lesions of the uterine cervix. AIM: To estimate the frequency of human papillomavirus (HPV) positivity in a group of Albanian women, the prevalence of vaginal coinfections, and the relationship of coinfections with HPV, as well as their role in metaplasia or cervical intraepithelial lesions (CIN). MATERIALS AND METHODS: In this retrospective study, 2075 vaginal smears were examined...
January 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28179702/knowledge-and-practices-of-nurses-on-cervical-cancer-hpv-and-hpv-vaccine-in-cankiri-state-hospital-turkey
#17
Ilknur Gol, OzUm Erkin
OBJECTIVE: To determine knowledge and practices of nurses on cervical cancer, human papillomavirus and its vaccine. METHODS: This descriptive study was conducted at Cankiri Karatekin University, Cankiri, Turkey, from December 2015 to January 2016, and included nurses. . A survey was used to collect data about socio-demographic features and knowledge and practices on cervical cancer and screening, signs and symptoms of cervical cancer and human papillomavirus vaccine...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28144096/burden-of-cervical-cancer-and-role-of-screening-in-india
#18
Saurabh Bobdey, Jignasa Sathwara, Aanchal Jain, Ganesh Balasubramaniam
BACKGROUND: Cervical cancer is a major cause of cancer mortality in women and more than a quarter of its global burden is contributed by developing countries. In India, in spite of alarmingly high figures, there is no nationwide government-sponsored screening program. This study was conducted to assess the burden of cervical cancer in India and review the performance characteristics of available cervical cancer screening tools, so as to provide evidence-based recommendations for application of most practically suited screening test to be used in resource-poor field settings...
October 2016: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/28121939/multiple-preinvasive-and-invasive-hpv-related-lesions-of-the-anogenital-tract-in-a-female-patient-with-hiv-infection-a-case-report
#19
Nicolò Clemente, Lara Alessandrini, Emanuela Vaccher, Antonino De Paoli, Monica Buttignol, Vincenzo Canzonieri, Francesco Sopracordevole
RATIONALE: Patients with human immunodeficiency virus (HIV) infection have been shown to be at increased risk for high-risk human papillomavirus (HR-HPV) infection of the anogenital tract. Furthermore, in the last decades, the introduction of highly active antiretroviral therapy (HAART) has increased the longevity of these patients who now live long enough to develop HPV-related cancers; hence, the impact of HPV infection on HIV-positive patients is of increasing concern. PATIENT CONCERNS: We reported the case of an HIV-positive female patient on HAART with a good virological and immunological response and with a long history of HPV-related intraepithelial and invasive lesions of the anogenital tract...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28086983/mailed-hpv-self-sampling-for-cervical-cancer-screening-among-underserved-minority-women-study-protocol-for-a-randomized-controlled-trial
#20
Erin Kobetz, Julia Seay, Anthony Amofah, Larry Pierre, Jordan Baeker Bispo, Dinah Trevil, Martha Gonzalez, Martine Poitevien, Tulay Koru-Sengul, Olveen Carrasquillo
BACKGROUND: Underserved ethnic minority women experience significant disparities in cervical cancer incidence and mortality, mainly due to lack of cervical cancer screening. Barriers to Pap smear screening include lack of knowledge, lack of health insurance and access, and cultural beliefs regarding disease prevention. In our previous SUCCESS trial, we demonstrated that HPV self-sampling delivered by a community health worker (CHW) is efficacious in circumventing these barriers. This approach increased screening uptake relative to navigation to Pap smear screening...
January 13, 2017: Trials
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