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Metin Ercan, Mehmet Aziret, Kerem Karaman, Birol Bostancı, Musa Akoğlu
INTRODUCTION: Diaphragmatic hernia secondary to traumatic rupture is a rare entity which can occur after stab wound injuries or blunt abdominal traumas. We aimed to report successfully management of dual mesh repair for a large diaphragmatic defect. CASE REPORT: A 66-year-old male was admitted with a right sided diaphragmatic hernia which occurred ten years ago due to a traffic accident. He had abdominal pain with worsened breath. Chest X-ray showed an elevated right diaphragm...
October 11, 2016: International Journal of Surgery Case Reports
Fen Wei, Jie Chen, Xinye Chen, Baolong Bao
Flatfish with left-right eye asymmetry are the most significant among vertebrates. However, the genetic basis for the control of this characteristic is still unclear. We propose that the gene(s) for eye asymmetry initially control minor differences in cell number in the tissues around the eyes during development. This minor difference is then amplified, causing eye migration during metamorphosis. Therefore, comparing the neurula transcriptomes between flatfish species with different eye-reversal mutants may provide very useful information to screen for genes involved in eye asymmetry...
October 14, 2016: Gene
Jezkova Eva, Kajo Karol, Zubor Pavol, Grendar Marian, Malicherova Bibiana, Mendelova Andrea, Dokus Karol, Lasabova Zora, Plank Lukas, Danko Jan
Breast cancer is a heterogeneous disease with very different responses to therapy and different length of survival. In many cases, however, the determination of the stage and histopathological characteristics of breast cancer is insufficient to predict prognosis and response to treatment for the vast heterogeneity of the disease. To understand the molecular signature of subtypes of breast cancer, we attempted to identify the methylation status of key tumour suppressor gene Ras association (RalGDS/AF-6) domain family member 1 isoform a (RASSF1A) and a member of the paired-like homeodomain transcription factor family which functions in left-right asymmetry development (PITX2) and to correlate results with known clinicopathological features of breast cancer...
October 15, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
Kouichiro Minami, Yota Kokubo, Ichinosuke Maeda, Shingo Hibino
In chest compression for cardiopulmonary resuscitation (CPR), the lower half of the sternum is pressed according to the American Heart Association (AHA) guidelines 2010. These have been no studies which identify the exact location of the applied by individual chest compressions. We developed a rubber power-flexible capacitive sensor that could measure the actual pressure point of chest compression in real time. Here, we examined the pressure point of chest compression by ambulance crews during CPR using a mannequin...
October 14, 2016: Journal of Anesthesia
Apoorva Trivedi, Takamura Ashikaga, Daphne Hard, Jessica Archambault, Martin Lachaine, David T Cooper, Harold James Wallace
PURPOSE: Transperineal ultrasound (TPUS) allows for continuous imaging of the prostate gland, but the accuracy of TPUS has not been rigorously studied. We determined the feasibility of prostate imaging with TPUS and subsequently compared prostate localization with TPUS and computed tomography (CT). METHODS AND MATERIALS: We completed 2 sequential evaluations of TPUS. The feasibility study included 15 men with localized prostate cancer and tested if TPUS adequately imaged the prostate...
September 2, 2016: Practical Radiation Oncology
G Scerrino, M Attard, C Lo Piccolo, A Attard, G I Melfa, C Raspanti, M Zarcone, S Bonventre, S Mazzola, G Gulotta
INTRODUCTION AND OBJECTIVES: Primary hyperparathyroidism (PHPT) can be found in concomitance with thyroid disease (TD) in a high frequency of cases. In this context the diagnostic exams for localizing the enlarged parathyroid(s) gland(s) could be less reliable or nonconclusive. Moreover, the thyroid carcinoma seems to be more frequent compared to that isolated thyroid desease and, therefore, carefully investigated. The main goal of the present study is to evaluate which diagnostic tool (US, MIBI) is more reliable for localizing the site of the PTH hypersecretion and to confirm if it is always advantageous a combination of both exams...
May 2016: Il Giornale di Chirurgia
Julia A Clarke, Sankar Chatterjee, Zhiheng Li, Tobias Riede, Federico Agnolin, Franz Goller, Marcelo P Isasi, Daniel R Martinioni, Francisco J Mussel, Fernando E Novas
From complex songs to simple honks, birds produce sounds using a unique vocal organ called the syrinx. Located close to the heart at the tracheobronchial junction, vocal folds or membranes attached to modified mineralized rings vibrate to produce sound. Syringeal components were not thought to commonly enter the fossil record, and the few reported fossilized parts of the syrinx are geologically young (from the Pleistocene and Holocene (approximately 2.5 million years ago to the present)). The only known older syrinx is an Eocene specimen that was not described or illustrated...
October 12, 2016: Nature
Berna A Yildirim, Cem Onal, Yemliha Dolek
PURPOSE: To compare soft-tissue cone-beam computed tomography (CBCT-P) and fiducial marker (CBCT-FM)-based image guided radiotherapy in prostate cancer patients. MATERIALS AND METHODS: Sixteen prostate cancer patients were treated with volumetric modulated arc therapy. Manual alignment using CBCT-P and CBCT-FM was performed for each patient. Couch shifts were calculated and compared between methods in the left-right (x), superior-inferior (y), and anterior-posterior (z) directions...
October 11, 2016: Japanese Journal of Radiology
Yi Chen, Jinyan Jiang, Yuehong Wu, Jingjing Yan, Huali Chen, Xuemei Zhu
OBJECTIVE: The objective of the study is to investigate whether hospital-based transitional care can reduce the postoperative complication in patients who received enterostomy or not by pooling the published prospective clinical studies. MATERIALS AND METHODS: Prospective clinical studies related to hospital-based transitional care for reducing the postoperative complication in patients with enterostomy were searched in the electronic databases of PubMed, Medline, EMBASE, CNKI, and Wanfang...
October 2016: Journal of Cancer Research and Therapeutics
Guozhen Luo, Joseph S Neimat, Anthony Cmelak, Austin N Kirschner, Albert Attia, Manuel Morales-Paliza, George X Ding
PURPOSE: To report on radiosurgery delivery positioning accuracy in the treatment of tremor patients with frameless image guided radiosurgery using the linear accelerator (LINAC) based ExacTrac system and to describe quality assurance (QA) procedures used. METHODS AND MATERIALS: Between 2010 and 2015, 20 patients underwent radiosurgical thalamotomy targeting the ventral intermediate nucleus for the treatment of severe tremor. The median prescription dose was 140 Gy (range, 120-145 Gy) in a single fraction...
August 20, 2016: Practical Radiation Oncology
Diego Raimondo, Aly Youssef, Mohamed Mabrouk, Simona Del Forno, Valentina Martelli, Gianluigi Pilu, Nicola Rizzo, Letizia Zannoni, Roberto Paradisi, Renato Seracchioli
OBJECTIVE: Pelvic floor muscle (PFM) dysfunction seems to play an important role in the pathophysiology of pain in women with with pelvic pain syndromes, including deep infiltrating endometriosis (DIE). The aim of the study was to evaluate static and dynamic morphometry of PFM in women affected by DIE, in comparison to asymptomatic control women, using three-dimensional (3D) and four-dimensional (4D) transperineal ultrasound. METHODS: A pilot, prospective study was conducted between March 2015 and November 2015, at our tertiary center...
October 8, 2016: Ultrasound in Obstetrics & Gynecology
Yipeng An, Mengjun Zhang, Dapeng Wu, Tianxing Wang, Zhaoyong Jiao, Congxin Xia, Zhaoming Fu, Kun Wang
We investigate the electronic transport properties of four types of lateral graphene/h-BN nanoribbon heterojunctions using the non-equilibrium Green's function method in combination with the density functional theory. The results show that the heterojunction displays an interesting rectifying effect when the interface has a left-right type structure, while a pronounced negative differential resistance (NDR) effect when the interface has an up-down type structure. Moreover, when the interface of the heterojunction has a left-bank or right-bank type structure, it presents the rectifying (with a larger rectification ratio) and NDR effects...
October 12, 2016: Physical Chemistry Chemical Physics: PCCP
Zhengyi Zhao, Hui Zhang, Dan Shu, Carlo Montemagno, Baoquan Ding, Jingyuan Li, Peixuan Guo
The significance of bionanomotors in nanotechnology is analogous to mechanical motors in daily life. Here the principle and approach for designing and constructing biomimetic nanomotors with continuous single-directional motion are reported. This bionanomotor is composed of a dodecameric protein channel, a six-pRNA ring, and an ATPase hexamer. Based on recent elucidations of the one-way revolving mechanisms of the phi29 double-stranded DNA (dsDNA) motor, various RNA and protein elements are designed and tested by single-molecule imaging and biochemical assays, with which the motor with active components has been constructed...
October 6, 2016: Small
Martin G Bleichner, Bojana Mirkovic, Stefan Debener
OBJECTIVE: This study presents a direct comparison of a classical EEG cap setup with a new around-the-ear electrode array (cEEGrid) to gain a better understanding of the potential of ear-centered EEG. APPROACH: Concurrent EEG was recorded from a classical scalp EEG cap and two cEEGrids that were placed around the left and the right ear. Twenty participants performed a spatial auditory attention task in which three sound streams were presented simultaneously. The sound streams were three seconds long and differed in the direction of origin (front, left, right) and the number of beats (3, 4, 5 respectively), as well as the timbre and pitch...
October 5, 2016: Journal of Neural Engineering
Joonbum Lee, Bruce Mehler, Bryan Reimer, Kazutoshi Ebe, Joseph F Coughlin
OBJECTIVE: Research has established that long off-road glances increase crash risk, and other work has shown increased off-road glance behavior in older drivers. This study investigated the relationship between older drivers' (M = 66.3, range 61-69 years) cognitive abilities and the duration of off-road glances while engaged in secondary visual-manual activities. METHOD: Twenty-two drivers completed the Montreal Cognitive Assessment (MoCA) prior to driving an instrumented vehicle and completing a set of radio-tuning tasks...
October 3, 2016: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
Elena Azañón, Kim Mihaljevic, Matthew R Longo
To perceive the location of touch in space, we integrate information about skin-location with information about the location of that body part in space. Most research investigating this process of tactile spatial remapping has used the so-called crossed-hands deficit, in which the ability to judge the temporal order of touches on the two hands is impaired when the arms are crossed. This posture induces a conflict between skin-based and tactile external spatial representations, specifically in the left-right dimension...
September 30, 2016: Cognition
Petroula Proitsi, Min Kim, Luke Whiley, Andrew Simmons, Martina Sattlecker, Latha Velayudhan, Michelle K Lupton, Hillka Soininen, Iwona Kloszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Simon Lovestone, John F Powell, Richard J B Dobson, Cristina Legido-Quigley
INTRODUCTION: The aim of this study was to (1) replicate previous associations between six blood lipids and Alzheimer's disease (AD) (Proitsi et al 2015) and (2) identify novel associations between lipids, clinical AD diagnosis, disease progression and brain atrophy (left/right hippocampus/entorhinal cortex). METHODS: We performed untargeted lipidomic analysis on 148 AD and 152 elderly control plasma samples and used univariate and multivariate analysis methods...
September 28, 2016: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
Karin M Vander Heyden, Mariette Huizinga, Maartje E J Raijmakers, Jelle Jolles
The current study investigated development and strategy use of spatial perspective taking (i.e., the ability to represent how an object or array of objects looks from other viewpoints) in children between 8 and 12years of age. We examined this ability with a task requiring children to navigate a route through a model city of wooden blocks from a 90° and 180° rotated perspective. We tested two hypotheses. First, we hypothesized that children's perspective-taking skills increase during this age period and that this process is related to a co-occurring increase in working memory capacity...
September 27, 2016: Journal of Experimental Child Psychology
Sebastian Ocklenburg, Patrick Friedrich, Onur Güntürkün, Erhan Genç
Handedness is thought to originate in the brain, but identifying its structural correlates in the cortex has yielded surprisingly incoherent results. One idea proclaimed by several authors is that structural grey matter asymmetries might underlie handedness. While some authors have found significant associations with handedness in different brain areas (e.g. in the central sulcus and precentral sulcus), others have failed to identify such associations. One method used by many researchers to determine structural grey matter asymmetries is voxel based morphometry (VBM)...
October 28, 2016: Neuroscience Letters
Frederik Crop, David Pasquier, Amandine Baczkiewic, Julie Doré, Lena Bequet, Emeline Steux, Anne Gadroy, Jacqueline Bouillon, Clement Florence, Laurence Muszynski, Mathilde Lacour, Eric Lartigau
A surface imaging system, Catalyst (C-Rad), was compared with laser-based positioning and daily mega voltage computed tomography (MVCT) setup for breast patients with nodal involvement treated by helical TomoTherapy. Catalyst-based positioning performed better than laser-based positioning. The respective modalities resulted in a standard deviation (SD), 68% confidence interval (CI) of positioning of left-right, craniocaudal, anterior-posterior, roll: 2.4 mm, 2.7 mm, 2.4 mm, 0.9° for Catalyst positioning, and 6...
2016: Journal of Applied Clinical Medical Physics
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