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https://www.readbyqxmd.com/read/29156215/gadolinium-perturbs-expression-of-skeletogenic-genes-calcium-uptake-and-larval-development-in-phylogenetically-distant-sea-urchin-species
#1
Chiara Martino, Caterina Costa, Maria Carmela Roccheri, Demian Koop, Rosaria Scudiero, Maria Byrne
Chelates of Gadolinium (Gd), a lanthanide metal, are employed as contrast agents for magnetic resonance imaging and are released into the aquatic environment where they are an emerging contaminant. We studied the effects of environmentally relevant Gd concentrations on the development of two phylogenetically and geographically distant sea urchin species: the Mediterranean Paracentrotus lividus and the Australian Heliocidaris tuberculata. We found a general delay of embryo development at 24h post-fertilization, and a strong inhibition of skeleton growth at 48h...
November 11, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/29153332/sensorimotor-performance-and-function-in-people-with-osteoarthritis-of-the-hand-a-case-control-comparison
#2
Nicoló Edoardo Magni, Peter John McNair, David Andrew Rice
OBJECTIVES: To determine whether hand left/right judgements, tactile acuity, and body perception are impaired in people with hand OA. To examine the relationships between left right judgements, tactile acuity and hand pain. To explore the relationships between sensorimotor measures (left/right judgements and tactile acuity) and measures of hand function in people with hand OA. METHODS: Twenty patients with symptomatic hand OA and 19 healthy pain-free controls undertook a hand left/right judgment task, a control left/right judgement task, two-point discrimination (TPD) threshold testing (assessing tactile acuity), a neglect-like symptoms questionnaire (assessing body perception) and several established measures of hand function...
September 25, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29145478/electrical-impedance-tomography-amplitudes-of-cardiac-related-impedance-changes-in-the-lung-are-highly-position-dependent
#3
Michael Graf, Thomas Riedel
BACKGROUND: Electrical impedance tomography (EIT) is used on the thorax to measure impedance changes due to the presence of air and blood in the lung. This experimental study was performed to investigate the effect of posture on cardiac and respiratory related impedance changes. METHODS: EIT measurements were performed on 14 healthy subjects in left-, right lateral, prone, supine and upright positions. Simultaneously, tidal volume was recorded with an ultrasonic flowmeter...
2017: PloS One
https://www.readbyqxmd.com/read/29140250/gdf3-is-required-for-robust-nodal-signaling-during-germ-layer-formation-and-left-right-patterning
#4
Jose L Pelliccia, Granton A Jindal, Rebecca D Burdine
Vertebrate embryonic patterning depends on signaling from Nodal, a TGFβ superfamily member. There are three Nodal orthologs in zebrafish; southpaw directs left-right asymmetries, while squint and cyclops function earlier to pattern mesendoderm. TGFβ member Vg1 is implicated in mesoderm formation but the role of the zebrafish ortholog, Growth differentiation factor 3 (Gdf3), has not been fully explored. We show that zygotic expression of gdf3 is dispensable for embryonic development, while maternally deposited gdf3 is required for mesendoderm formation and dorsal-ventral patterning...
November 15, 2017: ELife
https://www.readbyqxmd.com/read/29137676/a-medium-invasiveness-multi-level-patient-s-specific-template-for-pedicle-screw-placement-in-the-scoliosis-surgery
#5
Farhad Azimifar, Kamran Hassani, Amir Hossein Saveh, Farhad Tabatabai Ghomsheh
BACKGROUND: Several methods including free-hand technique, fluoroscopic guidance, image-guided navigation, computer-assisted surgery system, robotic platform and patient's specific templates are being used for pedicle screw placement. These methods have screw misplacements and are not always easy to be applied. Furthermore, it is necessary to expose completely a large portions of the spine in order to access fit entirely around the vertebrae. METHODS: In this study, a multi-level patient's specific template with medium invasiveness was proposed for pedicle screw placement in the scoliosis surgery...
November 14, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29136516/the-order-of-information-processing-alters-economic-gain-loss-framing-effects
#6
Youngbin Kwak, Scott Huettel
Adaptive decision making requires analysis of available information during the process of choice. In many decisions that information is presented visually - which means that variations in visual properties (e.g., salience, complexity) can potentially influence the process of choice. In the current study, we demonstrate that variation in the left-right positioning of risky and safe decision options can influence the canonical gain-loss framing effect. Two experiments were conducted using an economic framing task in which participants chose between gambles and certain outcomes...
November 11, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/29134789/either-at-left-or-right-both-high-and-low-frequency-rtms-of-dorsolateral-prefrontal-cortex-decreases-cue-induced-craving-for-methamphetamine
#7
Qingming Liu, Ying Shen, Xinyu Cao, Yongqiang Li, Yijiang Chen, Wei Yang, Ti-Fei Yuan
BACKGROUND AND OBJECTIVES: The study is to investigate if left or right dorsolateral prefrontal cortex is important in modulating the craving to drug related cues. METHODS: The present investigation examined different combinations between left/right and high/low frequency rTMS on cue induced craving to methamphetamine, with active sham rTMS on P3 region on a total of 50 subjects. RESULTS: The results showed that either at left or right side, both high and low frequency rTMS are effective in decreasing the cue induced craving to methamphetamine...
November 14, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/29134168/anatomical-region-segmentation-for-objective-surgical-skill-assessment-with-operating-room-motion-data
#8
Yangming Li, Randall A Bly, R Alex Harbison, Ian M Humphreys, Mark E Whipple, Blake Hannaford, Kris S Moe
Background  Most existing objective surgical motion analysis schemes are limited to structured surgical tasks or recognition of motion patterns for certain categories of surgeries. Analyzing instrument motion data with respect to anatomical structures can break the limit, and an anatomical region segmentation algorithm is required for the analysis. Methods  An atlas was generated by manually segmenting the skull base into nine regions, including left/right anterior/posterior ethmoid sinuses, frontal sinus, left and right maxillary sinuses, nasal airway, and sphenoid sinus...
December 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29131346/evaluation-of-the-latency-and-the-beam-characteristics-of-a-respiratory-gating-system-using-an-elekta-linear-accelerator-and-a-respiratory-indicator-device-abches
#9
Masahide Saito, Naoki Sano, Koji Ueda, Yuki Shibata, Kengo Kuriyama, Takafumi Komiyama, Kan Marino, Shinichi Aoki, Hiroshi Onishi
PURPOSE: To evaluate the basic performance of a respiratory gating system using an Elekta linac and an Abches respiratory monitoring device. METHODS: The gating system was comprised of an Elekta Synergy linac equipped with a Response(TM) gating interface module and an Abches respiratory monitoring device. The latencies from a reference respiratory signal to the resulting Abches gating output signal and the resulting monitor-ion-chamber output signal were measured...
November 13, 2017: Medical Physics
https://www.readbyqxmd.com/read/29130952/efferent-axonal-projections-of-the-habenular-complex-in-the-fire-bellied-toad-bombina-orientalis
#10
Frédéric Laberge, Allison Smith
The habenular complex and its associated axonal pathways are often thought of as phylogenetically conserved features of the brain among vertebrates despite the fact that detailed studies of this brain region are limited to a few species. Here, the gross morphology and axonal projection pattern of the habenular complex of an anuran amphibian, the fire-bellied toad Bombina orientalis, was studied to allow comparison with the situation in other vertebrates. Axonal pathways were traced using biocytin applications in dissected brain preparations...
November 2, 2017: Brain, Behavior and Evolution
https://www.readbyqxmd.com/read/29129577/pelvic-bone-anatomy-vs-implanted-gold-seed-marker-registration-for-image-guided-intensity-modulated-radiotherapy-for-prostate-carcinoma-comparative-analysis-of-inter-fraction-motion-and-toxicities
#11
Madhup Rastogi, Sambit Swarup Nanda, Ajeet Kumar Gandhi, Divakar Dalela, Rohini Khurana, Surendra Prasad Mishra, Anoop Srivastava, S Farzana, Madan Lal Brahma Bhatt, Nuzhat Husain
OBJECTIVES: We compared the prostate motion variability and toxicities between patients treated with gold marker registration based IG-IMRT (IG-IMRT-M) and bony landmark registration based IG-IMRT (IG-IMRT-B). METHODS: T1c-T3b (node negative), intermediate and high risk (non-metastatic) adenocarcinoma of prostate, age ≥18years, Karnofsky Performance Status of ≥70 were included in this retrospective study. The prostate motion variability, acute and late radiation toxicities between the two treatment arms (IG-IMRT-M versus IG-IMRT-B) were compared...
November 9, 2017: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/29127879/role-of-the-right-inferior-parietal-cortex-in-auditory-selective-attention-an-rtms-study
#12
Corinne A Bareham, Stanimira D Georgieva, Marc R Kamke, David Lloyd, Tristan A Bekinschtein, Jason B Mattingley
Selective attention is the process of directing limited capacity resources to behaviourally relevant stimuli while ignoring competing stimuli that are currently irrelevant. Studies in healthy human participants and in individuals with focal brain lesions have suggested that the right parietal cortex is crucial for resolving competition for attention. Following right-hemisphere damage, for example, patients may have difficulty reporting a brief, left-sided stimulus if it occurs with a competitor on the right, even though the same left stimulus is reported normally when it occurs alone...
October 16, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29126774/fixating-at-far-distance-shortens-reaction-time-to-peripheral-visual-stimuli-at-specific-locations
#13
Masahiro Kokubu, Soichi Ando, Shingo Oda
The purpose of the present study was to examine whether the fixation distance in real three-dimensional space affects manual reaction time to peripheral visual stimuli. Light-emitting diodes were used for presenting a fixation point and four peripheral visual stimuli. The visual stimuli were located at a distance of 45cm and at 25° in the left, right, upper, and lower directions from the sagittal axis including the fixation point. Near (30cm), Middle (45cm), Far (90cm), and Very Far (300cm) fixation distance conditions were used...
November 7, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29125129/left-right-asymmetry-in-firing-rate-of-extra-retinal-photosensitive-neurons-in-the-crayfish
#14
José A Pacheco-Ortiz, Juan C Sánchez-Hernández, Leonardo Rodríguez-Sosa, Gabina Calderón-Rosete, Edgar Villagran-Vargas
The purpose of this paper is to explore the firing rate of the caudal photoreceptors (CPRs) from the sixth abdominal ganglion of the crayfish Cherax quadricarinatus. We use simultaneous extracellular recordings on left and right CPR in the isolated ganglion (n = 10). The CPRs showed an asymmetry in the spontaneous activity and light-induced response. In darkness, we observed one subgroup (70%) in which the left CPR (CPR-L) and right CPR (CPR-R) had spontaneous firing rates with a median of 18 impulses/s and 6 impulses/s, respectively...
November 10, 2017: General Physiology and Biophysics
https://www.readbyqxmd.com/read/29123475/cerebello-cortical-differences-in-effective-connectivity-of-the-dominant-and-non-dominant-hand-during-a-visuomotor-paradigm-of-grip-force-control
#15
Eric Moulton, Cécile Galléa, Claire Kemlin, Romain Valabregue, Marc A Maier, Pavel Lindberg, Charlotte Rosso
Structural and functional differences are known to exist within the cortical sensorimotor networks with respect to the dominant vs. non-dominant hand. Similarly, the cerebellum, a key structure in the sensorimotor network with its cerebello-cortical connections, has been reported to respond differently when using the dominant vs. non-dominant hand. Several groups have already investigated causal interactions during diverse motor paradigms using effective connectivity but few have studied the larger visuomotor network, including key structures such as the parietal cortex and the cerebellum, with both hands...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29122841/hh-gene-participates-in-the-left-right-asymmetry-development-of-amphioxus-by-controlling-cer-expression
#16
Guangwei Hu, Guang Li, Hui Wang, Yiquan Wang
Correct patterning of left-right asymmetry is an important process during the embryonic development of bilaterians. It is known that Hh signaling plays a role in LR asymmetry development of mouse, chicken and sea urchin embryos by regulating Nodal expression. In this study, we reported a novel regulating way of Hh gene in the LR asymmetry development of amphioxus embryos. Our results revealed that Hh(-/-) embryos abolished Cerburs (Cer) transcription and led to bilaterally symmetric expression of Nodal, Lefty and Pitx As a consequence, Hh(-/-) mutants duplicated its left-side structures and lost right-side characters displaying an abnormal bilaterally symmetric body plan...
November 9, 2017: Development
https://www.readbyqxmd.com/read/29116716/articular-eminence-inclination-in-medieval-and-contemporary-croatian-population
#17
Josip Kranjčić, Mario Šlaus, Marin Vodanović, Sanja Peršić, Denis Vojvodić
Articular eminence inclination (AEI) of the temporomandibular joint leads the mandible in its movements. Therefore, the aim of the present study was to determine AEI values in medieval (MP) and recent (RP) Croatian population. The study was carried out on two groups of specimens: first group with 30 MP human dry skulls, while the other, serving as control group consisted of 137 dry skulls. The AEI was measured on lateral digital skull images as the angle between the best fi t line drawn along the posterior wall of the articular eminence and the Frankfurt horizontal plane...
December 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29114612/simulating-intrafraction-prostate-motion-with-a-random-walk-model
#18
Tobias Pommer, Jung Hun Oh, Per Munck Af Rosenschöld, Joseph O Deasy
Purpose: Prostate motion during radiation therapy (ie, intrafraction motion) can cause unwanted loss of radiation dose to the prostate and increased dose to the surrounding organs at risk. A compact but general statistical description of this motion could be useful for simulation of radiation therapy delivery or margin calculations. We investigated whether prostate motion could be modeled with a random walk model. Methods and materials: Prostate motion recorded during 548 radiation therapy fractions in 17 patients was analyzed and used for input in a random walk prostate motion model...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29114611/2d-kv-orthogonal-imaging-with-fiducial-markers-is-more-precise-for-daily-image-guided-alignments-than-soft-tissue-cone-beam-computed-tomography-for-prostate-radiation-therapy
#19
Peter H Goff, Louis B Harrison, Eli Furhang, Evan Ng, Stephen Bhatia, Frieda Trichter, Ronald D Ennis
Purpose: The hypothesis is that 2-dimensional kV orthogonal imaging with fiducial markers (kV-FM) and soft-tissue cone beam computed tomography (ST-CBCT) are equally reproducible for daily positional alignments for image guided (IG) intensity modulated radiation therapy (IMRT) for prostate cancer. Methods and materials: Ten patients undergoing definitive treatment for prostate cancer with IG-IMRT were imaged daily with kV-FM and ST-CBCT. For each acquired kV and CBCT image, offline alignments to the digitally reconstructed radiograph or planning CT, respectively, were made twice by the same physician to assess intraobserver test-retest reproducibility...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29114109/frequency-of-acccessory-renal-arteries-diagnosed-by-computerized-tomography
#20
Sabina Prevljak, Edin Prelevic, Salih Mesic, Odey Ali Abud, Spomenka Kristic, Sandra Vegar-Zubovic
Introduction: Accessory renal arteries play a significant role in kidney and abdominal aorta surgery, and renovascular hypertension. In the published literature, the frequency varies considerably, depending on the size of the sample, the method of examination and the ethnic group. Materials and Methods: The aim of this study is to determine the general frequency of accessory renal arteries, their frequency in relation to gender, the origin and the vascularization area, and to determine the differences in left-right and bilateral distribution...
September 2017: Acta Informatica Medica: AIM
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