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https://www.readbyqxmd.com/read/29333959/a-noninvasive-body-setup-method-for-radiotherapy-by-using-a-multimodal-image-fusion-technique
#1
Jie Zhang, Ying Chen, Yunxia Chen, Chenchen Wang, Jing Cai, Kaiyue Chu, Jianhua Jin, Yun Ge, Xiaolin Huang, Yue Guan, Weifeng Li
PURPOSE: To minimize the mismatch error between patient surface and immobilization system for tumor location by a noninvasive patient setup method. MATERIALS AND METHODS: The method, based on a point set registration, proposes a shift for patient positioning by integrating information of the computed tomography scans and that of optical surface landmarks. An evaluation of the method included 3 areas: (1) a validation on a phantom by estimating 100 known mismatch errors between patient surface and immobilization system...
December 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/29332454/intrafractional-tracking-accuracy-of-a-transperineal-ultrasound-image-guidance-system-for-prostate-radiotherapy
#2
Amy S Yu, Mohammad Najafi, Dimitre H Hristov, Tiffany Phillips
PURPOSE: The aim of this study is to evaluate the tracking accuracy of a commercial ultrasound system under relevant treatment conditions and demonstrate its clinical utility for detecting significant treatment deviations arising from inadvertent intrafractional target motion. METHODS: A multimodality male pelvic phantom was used to simulate prostate image-guided radiotherapy with the system under evaluation. Target motion was simulated by placing the phantom on a motion platform...
December 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/29329997/clinical-log-data-analysis-for-assessing-the-accuracy-of-the-cyberknife-fiducial-free-lung-tumor-tracking-system
#3
Masao Nakayama, Hideki Nishimura, Hiroshi Mayahara, Masaki Nakamura, Kazuyuki Uehara, Shinji Tsudou, Aya Harada, Hiroaki Akasaka, Ryohei Sasaki
PURPOSE: The CyberKnife Xsight Lung Tracking (XLT) and 1-View tracking systems can synchronize beam targeting to a visible lung tumor with respiratory motion during irradiation without requiring internal fiducial markers. The systems use a correlation model that relates external marker positions to tumor positions as well as a prediction model that predicts the target's future position. In this study, the correlation and prediction model uncertainties related to the CyberKnife fiducial-free tumor tracking system were evaluated using clinical log data...
November 4, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29329741/sex-differences-of-hippocampal-structure-in-bipolar-disorder
#4
Jing Shi, Hua Guo, Fengmei Fan, Hongzhen Fan, Huimei An, Zhiren Wang, Shuping Tan, Fude Yang, Yunlong Tan
Although differential patterns in clinical characteristics have been consistently noted between male and female patients with bipolar disorder (BD), the effect of sex on the hippocampal structure remains unclear. To address this, the present study investigated the effects of BD and sex on the hippocampal structure, and the relationship between the hippocampal structure and cognitive performance. Morphometric and neurocognitive analyses were performed in 91 subjects (patients with BD: male/female = 33/19; normal controls: male/female = 22/17)...
December 1, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29312752/adult-echocardiographic-nomograms-overview-critical-review-and-creation-of-a-software-for-automatic-fast-and-easy-calculation-of-normal-values
#5
REVIEW
Massimiliano Cantinotti, Raffaele Giordano, Marco Paterni, Daniel Saura, Marco Scalese, Eliana Franchi, Nadia Assanta, Martin Koestenberg, Raluca Dulgheru, Tadafumi Sugimoto, Anne Bernard, Luis Caballero, Patrizio Lancellotti
There is a crescent interest on normal adult echocardiographic values and the introduction of new deformation imaging and 3D parameters pose the issue of normative data. A multitude of nomograms has been recently published, however data are often fragmentary, difficult to find, and their strengths/limitations have been never evaluated. AIMS: (I) to provide a review of current echocardiographic nomograms; (II) to generate a tool for easy and fast access to these data. A literature search was conducted accessing the National Library of Medicine using the keywords: 2D/3D echocardiography, strain, left/right ventricle, atrial, mitral/tricuspid valve, aorta, reference values/nomograms/normal values...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29311614/closed-loop-control-of-trunk-posture-improves-locomotion-through-the-regulation-of-leg-proprioceptive-feedback-after-spinal-cord-injury
#6
Eduardo Martin Moraud, Joachim von Zitzewitz, Jenifer Miehlbradt, Sophie Wurth, Emanuele Formento, Jack DiGiovanna, Marco Capogrosso, Grégoire Courtine, Silvestro Micera
After spinal cord injury (SCI), sensory feedback circuits critically contribute to leg motor execution. Compelled by the importance to engage these circuits during gait rehabilitation, assistive robotics and training protocols have primarily focused on guiding leg movements to reinforce sensory feedback. Despite the importance of trunk postural dynamics on gait and balance, trunk assistance has comparatively received little attention. Typically, trunk movements are either constrained within bodyweight support systems, or manually adjusted by therapists...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29310525/proactive-and-reactive-motor-inhibition-in-top-athletes-versus-nonathletes
#7
Damien Brevers, Etienne Dubuisson, Fabien Dejonghe, Julien Dutrieux, Mathieu Petieau, Guy Cheron, Paul Verbanck, Jennifer Foucart
We examined proactive (early restraint in preparation for stopping) and reactive (late correction to stop ongoing action) motor response inhibition in two groups of participants: professional athletes ( n = 28) and nonathletes ( n = 25). We recruited the elite athletes from Belgian national taekwondo and fencing teams. We estimated proactive and reactive inhibition with a modified version of the stop-signal task (SST) in which participants inhibited categorizing left/right arrows. The probability of the stop signal was manipulated across blocks of trials by providing probability cues from the background computer screen color (green = 0%, yellow =17%, orange = 25%, red = 33%)...
January 1, 2018: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/29306590/new-definition-criteria-of-myocardial-dysfunction-in-patients-with-liver-cirrhosis-a-speckle-tracking-and-tissue-doppler-imaging-study
#8
Roxana Cristina Rimbaş, Sorina Mihăilă Baldea, Ruxandra Drăgoi Galrinho Antunes Guerra, Simona Ionela Visoiu, Mihai Rimbaş, Corina Silvia Pop, Dragoş Vinereanu
There are no clear recommendations regarding cirrhotic cardiomyopathy (CC) evaluation in patients with pre-transplant liver cirrhosis. The roles of new methods, tissue Doppler imaging (TDI) and speckle tracking echocardiography (STE) in the diagnosis and prognosis of cirrhotic cardiomyopathy remain controversial. We investigated the utility of TDI/STE parameters in cirrhotic cardiomyopathy diagnosis and also in predicting mortality in patients with liver cirrhosis. Left/right ventricular function was studied using conventional TDI (velocities) and STE (strain/strain rate)...
January 3, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29306254/three-dimensional-evaluation-of-pelvic-posture-in-adolescents-with-and-without-a-history-of-low-back-pain
#9
Seher Özyürek, Arzu Genç, Hayriye Kul Karaali, Zeliha Candan Algun
Background/aim: This study aimed to evaluate the three-dimensional (3D) profile of pelvic posture and postural displacements of the pelvis in adolescents with and without a history of low back pain (LBP). Materials and methods: Thirty-two adolescents participated in this study. Participants were asked if they had ever suffered LBP at some point in their lives. Participants were divided into two groups: with a history of LBP (LBP group) and without a history of LBP (control group). For 3D evaluation of pelvic posture, the PosturePrint system was used...
December 19, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29290587/rapgef5-regulates-nuclear-translocation-of-%C3%AE-catenin
#10
John N Griffin, Florencia Del Viso, Anna R Duncan, Andrew Robson, Woong Hwang, Saurabh Kulkarni, Karen J Liu, Mustafa K Khokha
Canonical Wnt signaling coordinates many critical aspects of embryonic development, while dysregulated Wnt signaling contributes to common diseases, including congenital malformations and cancer. The nuclear localization of β-catenin is the defining step in pathway activation. However, despite intensive investigation, the mechanisms regulating β-catenin nuclear transport remain undefined. In a patient with congenital heart disease and heterotaxy, a disorder of left-right patterning, we previously identified the guanine nucleotide exchange factor, RAPGEF5...
December 27, 2017: Developmental Cell
https://www.readbyqxmd.com/read/29289335/cognitive-consequences-of-the-left-right-asymmetry-of-atrophy-in-semantic-dementia
#11
Anna M Woollams, Karalyn Patterson
Semantic dementia (SD) is a condition in which atrophy to the anterior temporal lobes (ATL) produces a selective deterioration of conceptual knowledge. As this atrophy is always bilateral but usually asymmetrical, differences in performance of the two SD subgroups-with left > right (L > R) versus right > left (R > L) atrophy-constitute a major source of evidence regarding the roles of the left and right sides of this region. We explored this issue using large scale case-series methodology, with a pool of 216 observations of neuropsychological data from 72 patients with SD...
December 5, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29288683/what-is-difficult-for-you-can-be-easy-for-me-effects-of-increasing-individual-task-demand-on-prefrontal-lateralization-a-tdcs-study
#12
A Vergallito, Leonor J Romero Lauro, Rolando Bonandrini, Laura Zapparoli, Laura Danelli, Manuela Berlingeri
Neuroimaging studies suggest that increment of the cognitive load associated with a specific task may induce the recruitment of a more bilateral brain network. In most studies, however, task demand has been manipulated in a static and pre-specified way, regardless of individual cognitive resources. Here we implemented a new paradigm based on a pre-experimental assessment to set up subject-specific levels of task demand and applied tDCS (transcranial direct current stimulation) to assess each hemisphere involvement in task performance...
December 27, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29288102/a-split-face-single-blinded-randomized-controlled-comparison-of-alexandrite-755-nm-picosecond-laser-vs-alexandrite-755-nm-nanosecond-laser-in-the-treatment-of-acquired-bilateral-nevus-of-ota-like-macules-abnom
#13
Wenyou Yu, Jiafang Zhu, Wenxin Yu, Dongze Lyu, Xiaoxi Lin, Zhen Zhang
BACKGROUND: Q-switched alexandrite lasers (QSAL) have been used for the treatment of acquired bilateral nevus of Ota-like macules (ABNOM). Currently, picosecond alexandrite laser (PSAL) pulses have become available for pigmentary disorders. However, no studies have compared PSAL and QSAL in the treatment of ABNOM. OBJECTIVE: To compare the efficacy and safety of a PSAL and a QSAL in the treatment of ABNOM. METHODS: Each patient (n = 30) received three treatments at six-month intervals...
December 26, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29286065/anti-inflammatory-effects-of-lefty-1-in-renal-tubulointerstitial-inflammation-via-regulation-of-the-nf-%C3%AE%C2%BAb-pathway
#14
Lijun Zhang, Changgeng Xu, Wei Hu, Pin Wu, Cong Qin, Jie Zhang
Renal tubulointerstitial inflammation has an important role in fibrosis, which is the main pathogenetic alteration associated with chronic kidney disease (CKD). The left‑right determination factor 1 (Lefty‑1) gene pleiotropically and biologically regulates transforming growth factor, mitogen‑activated protein kinase and other signaling pathways, and is considered to have a potential anti‑inflammatory function. However, its role in renal tubulointerstitial inflammation, which is often a long‑term consequence of renal fibrosis, is currently unknown...
December 18, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29279982/mapping-of-non-numerical-domains-on-space-a-systematic-review-and-meta-analysis
#15
REVIEW
Anne Macnamara, Hannah A D Keage, Tobias Loetscher
The spatial numerical association of response code (SNARC) effect is characterized by low numbers mapped to the left side of space and high numbers mapped to the right side of space. In addition to numbers, SNARC-like effects have been found in non-numerical magnitude domains such as time, size, letters, luminance, and more, whereby the smaller/earlier and larger/later magnitudes are typically mapped to the left and right of space, respectively. The purpose of this systematic and meta-analytic review was to identify and summarise all empirical papers that have investigated horizontal (left-right) SNARC-like mappings using non-numerical stimuli...
December 26, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29279894/binaural-speech-understanding-with-bilateral-cochlear-implants-in-reverberation
#16
Kostas Kokkinakis
Purpose: The purpose of this study was to investigate whether bilateral cochlear implant (CI) listeners who are fitted with clinical processors are able to benefit from binaural advantages under reverberant conditions. Another aim of this contribution was to determine whether the magnitude of each binaural advantage observed inside a highly reverberant environment differs significantly from the magnitude measured in a near-anechoic environment. Method: Ten adults with postlingual deafness who are bilateral CI users fitted with either Nucleus 5 or Nucleus 6 clinical sound processors (Cochlear Corporation) participated in this study...
December 26, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/29273316/quantitative-assessment-and-interpretation-of-vaginal-conditions
#17
Vladimir Egorov, Miles Murphy, Vincent Lucente, Heather van Raalte, Sonya Ephrain, Nina Bhatia, Noune Sarvazyan
INTRODUCTION: Few means exist to provide quantitative and reproducible assessment of vaginal conditions from biomechanical and functional standpoints. AIM: To develop a new approach for quantitative biomechanical characterization of the vagina. METHODS: Vaginal tactile imaging (VTI) allows biomechanical assessment of soft tissue and function along the entire length of the anterior, posterior, and lateral vaginal walls. This can be done at rest, with applied vaginal deformation, and with pelvic muscle contraction...
December 19, 2017: Sexual Medicine
https://www.readbyqxmd.com/read/29259275/comparing-stroop-like-and-simon-effects-on-perceptual-features
#18
Elisa Scerrati, Luisa Lugli, Roberto Nicoletti, Carlo Umiltà
Stroop-like and Simon tasks produce two sources of interference in human information processing. Despite being logically similar, it is still debated whether the conflicts ensuing from the two tasks are resolved by the same or different mechanisms. In the present study, we compare two accounts of the Stroop-like effect. According to the Perceptual Account, the Stroop-like effect is due to Stimulus-Stimulus congruence. According to the Decisional Account, the Stroop-like effect results from the same mechanisms that produce the Simon effect, that is, Stimulus-Response compatibility...
December 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29259161/revealing-chiral-cell-motility-by-3d-riesz-transform-differential-interference-contrast-microscopy-and-computational-kinematic-analysis
#19
Atsushi Tamada, Michihiro Igarashi
Left-right asymmetry is a fundamental feature of body plans, but its formation mechanisms and roles in functional lateralization remain unclear. Accumulating evidence suggests that left-right asymmetry originates in the cellular chirality. However, cell chirality has not yet been quantitatively investigated, mainly due to the absence of appropriate methods. Here we combine 3D Riesz transform-differential interference contrast (RT-DIC) microscopy and computational kinematic analysis to characterize chiral cellular morphology and motility...
December 19, 2017: Nature Communications
https://www.readbyqxmd.com/read/29251798/lateral-ventricular-volume-measurement-by-3d-mr-hydrography-in-fetal-ventriculomegaly-and-normal-lateral-ventricles
#20
Si-Xiu Zhao, Yun-Hua Xiao, Fu-Rong Lv, Zhi-Wei Zhang, Bo Sheng, Hong-Li Ma
BACKGROUND: In fetuses with prenatal ventriculomegaly (VM), ventricular volume on MRI has been shown to correlate with poor postnatal outcomes and in utero death. 3D magnetic resonance hydrography (MRH) has been widely used for MR cholangiopancreatography. PURPOSE: To investigate the reliability of 3D MRH for lateral ventricular volume measurement in fetuses with VM and normal lateral ventricles, using manual multisection planimetry (MSP) as a reference standard...
December 18, 2017: Journal of Magnetic Resonance Imaging: JMRI
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