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https://www.readbyqxmd.com/read/27922661/fin-tiera-a-tool-for-assessing-technology-induced-errors
#1
Sari Palojoki, Tuuli Pajunen, Lasse Lehtonen, Kaija Saranto
BACKGROUND: Due to the complexity of healthcare processes, the potential for Health Information Systems (HIS) to cause technology-induced errors is a growing concern. Health Information Technology (HIT) errors nearly always threaten good patient care and can lead to patient harm. Instruments to allow hospitals to proactively identify areas of Electronic Health Records (EHR) safety, to set priorities and to intervene before incidents occur are currently underdeveloped. OBJECTIVES: The aim was to design a Finnish questionnaire to measure EHR users' perceptions of common EHR-related safety concerns in a specialized hospital district context through the lens of the theory of socio-technical dimensions...
December 6, 2016: Methods of Information in Medicine
https://www.readbyqxmd.com/read/27911310/cholinergic-modification-of-neurogenesis-and-gliosis-improves-the-memory-of%C3%A2-a%C3%AE-ppswe-psen1de9-alzheimer-s-disease-model-mice-fed-a-high-fat-diet
#2
Takeshi Matsuda, Tatsuhiro Hisatsune
We previously reported that neuroinflammation contributes to the amnesia of AβPPswe/PSEN1dE9 Alzheimer's disease model mice fed a high-fat diet to induce type-2 diabetes (T2DM-AD mice), but the underlying mechanism for the memory decline remained unclear. Recent studies have suggested that cholinergic modulation is involved in neuroinflammatory cellular reactions including neurogenesis and gliosis, and in memory improvement. In this study, we administered a broad-spectrum cholinesterase inhibitor, rivastigmine (2 mg/kg/day, s...
November 28, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27904438/article-watch-december-2016
#3
Clive A Slaughter
This column highlights recently published articles that are of interest to the readership of this publication. We encourage ABRF members to forward information on articles they feel are important and useful to Clive Slaughter, MCG-UGA Medical Partnership, 1425 Prince Ave., Athens, GA 30606, USA. Tel: (706) 713-2216; Fax: (706) 713-2221; E-mail: cslaught@uga.edu, or to any member of the editorial board. Article summaries reflect the reviewer's opinions and not necessarily those of the association.
December 2016: Journal of Biomolecular Techniques: JBT
https://www.readbyqxmd.com/read/27895717/interferon-%C3%AE-promotes-gastric-lymphoid-follicle-formation-but-not-gastritis-in-helicobacter-infected-balb-c-mice
#4
Michelle Chonwerawong, Patrick Avé, Michel Huerre, Richard L Ferrero
BACKGROUND: Mouse infection studies have shown that interferon-γ (IFN-γ), a T helper 1 (Th1) cytokine, is required for the development of severe pathology induced by chronic Helicobacter infection. This finding is largely based on studies performed using mice that have polarised Th1 responses i.e. C57BL/6 animals. The current work aims to investigate the role of IFN-γ in Helicobacter-induced inflammation in BALB/c mice which have Th2-polarised immune responses. RESULTS: At 7 months post-infection with Helicobacter felis, IFN-γ deficiency in BALB/c mice had no significant effect on H...
2016: Gut Pathogens
https://www.readbyqxmd.com/read/27878070/changing-climate-mediates-sapsucker-aves-sphyrapicus-hybrid-zone-movement
#5
Shawn M Billerman, Melanie A Murphy, Matthew D Carling
Hybrid zones, where two divergent taxa meet and interbreed, offer unique opportunities to investigate how climate contributes to reproductive isolation between closely related taxa and how these taxa may respond to climatic changes. Red-naped (Sphyrapicus nuchalis) and Red-breasted (Sphyrapicus ruber) sapsuckers (Aves: Picidae) hybridize along a narrow contact zone that stretches from northern California to British Columbia. The hybrid zone between these species has been studied extensively for more than 100 years and represents an excellent system for investigations of the evolution of reproductive isolation...
November 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/27869350/skeletogenesis-of-myiopsitta-monachus-psittaciformes-and-sequence-heterochronies-in-aves
#6
Julieta Carril, Claudia P Tambussi
The ossification sequence of Myiopsitta monachus was determined. Myiopsitta has a similar sequence to other altricial birds, with delayed skeletons compared to precocial species. The hindlimbs ossify before the forelimbs, a condition that could be linked to altriciality. To determine the stability of the sequences of ossification across birds, we selected species of different groups of Aves and used event-pairing method and character mapping on a phylogeny. Our results show that the homogeneity in the development of birds was supported by 56...
November 21, 2016: Evolution & Development
https://www.readbyqxmd.com/read/27868417/-evaluation-of-tear-film-and-meibomian-gland-function-in-dry-eye-patients-using-keratograph-5m
#7
Kexuan Zhu, Wenjia Xie, Jinglu Ying, Yufeng Yao
Objective: To assess the application of Keratograph 5M in evaluating tear film and meibomian gland function in patients with dry eye. Methods: A total of 144 eyes were recruited in the study, in which 72 eyes were from patients diagnosed with dry eye and 72 eyes were from healthy subjects. All subjects finished following tests or examinations:ocular surface disease index (OSDI) to evaluate eye symptoms; Keratograph 5M examination to obtain tear meniscus height (TMH), noninvasive tear break-up time (NIBUT) including first NIBUT (NIBUT-Fir) and average NIBUT (NIBUT-Ave), and infrared meibography; and fluorescein sodium staining to obtain fluorescein tearbreak-up time (FBUT)...
May 25, 2016: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/27867762/a-global-analysis-of-bird-plumage-patterns-reveals-no-association-between-habitat-and-camouflage
#8
Marius Somveille, Kate L A Marshall, Thanh-Lan Gluckman
Evidence suggests that animal patterns (motifs) function in camouflage. Irregular mottled patterns can facilitate concealment when stationary in cluttered habitats, whereas regular patterns typically prevent capture during movement in open habitats. Bird plumage patterns have predominantly converged on just four types-mottled (irregular), scales, bars and spots (regular)-and habitat could be driving convergent evolution in avian patterning. Based on sensory ecology, we therefore predict that irregular patterns would be associated with visually noisy closed habitats and that regular patterns would be associated with open habitats...
2016: PeerJ
https://www.readbyqxmd.com/read/27864320/three-questionnaires-to-assess-the-perception-of-fixed-orthodontic-therapy-before-during-and-after-treatment-validity-and-reliability
#9
Yassir A Yassir, Grant T McIntyre, David R Bearn
BACKGROUND/OBJECTIVE: To assess the validity and reliability of a series of three questionnaires for the quantification of patient perception of fixed appliance orthodontic treatment. SUBJECTS AND METHODS: The study was carried out at the University of Dundee with content and face validity being assessed using proformas. Initially ten experts (Orthodontic Specialists) assessed content validity with 11 professionals (seven Orthodontic Specialists and four Postgraduates) and 20 patients assessing face validity...
November 17, 2016: European Journal of Orthodontics
https://www.readbyqxmd.com/read/27862578/rapid-postglacial-diversification-and-long-term-stasis-within-the-songbird-genus-junco-phylogeographic-and-phylogenomic-evidence
#10
Guillermo Friis, Pau Aleixandre, Ricardo Rodríguez-Estrella, Adolfo G Navarro-Sigüenza, Borja Milá
Natural systems composed of closely-related taxa that vary in the degree of phenotypic divergence and geographic isolation, provide an opportunity to investigate the rate of phenotypic diversification and the relative roles of selection and drift in driving lineage formation. The genus Junco (Aves: Emberizidae) of North America includes parapatric northern forms that are markedly divergent in plumage pattern and color, in contrast to geographically isolated southern populations in remote areas that show moderate phenotypic divergence...
November 14, 2016: Molecular Ecology
https://www.readbyqxmd.com/read/27862572/how-do-frequent-users-of-crisis-helplines-differ-from-other-users-regarding-their-reasons-for-calling-results-from-a-survey-with-callers-to-lifeline-australia-s-national-crisis-helpline-service
#11
Aves Middleton, Alan Woodward, Jane Gunn, Bridget Bassilios, Jane Pirkis
Crisis helplines are designed to provide short-term support to people in an immediate crisis. However, there is a group of users who call crisis helplines frequently over an extended period of time. The reasons for their ongoing use remain unclear. The aim of this study was to investigate the differences in the reasons for calling between frequent and other users of crisis helplines. This was achieved by examining the findings from a brief survey completed by callers to Lifeline Australia at the end of their call between February and July 2015...
November 15, 2016: Health & Social Care in the Community
https://www.readbyqxmd.com/read/27854043/psychometric-properties-of-the-obstacles-to-return-to-work-questionnaire-in-a-brazilian-context
#12
Daniela Milani, Neusa Maria Costa Alexandre, Juliana Alvares Duarte Bonini Campos, Sheilah Hogg-Johnson
Purpose To evaluate the psychometric properties of the Obstacles to Return-to-Work Questionnaire (ORTWQ) among Brazilian workers on sick-leave due to musculoskeletal disorders. Methods Confirmatory factor analysis was conducted to evaluate the factor structure validity of the ORTWQ. Model fit indices and salience of factor loadings were assessed. The convergent validity was estimated using the Average Variance Extracted (AVE) and Composite Reliability (CR). The correlational analysis was verified using the Spearman Correlation between the ORTWQ and other specific tools...
November 16, 2016: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/27820679/malathion-dermal-permeability-in-relation-to-dermal-load-assessment-by-physiologically-based-pharmacokinetic-modeling-of-in-vivo-human-data
#13
Kenneth T Bogen, Ankur Singhal
Estimates of dermal permeability (Kp), obtained by fitting an updated human PBPK model for malathion to previously reported data on excreted urinary metabolites after 29 volunteers were dermally exposed to measured values of [(14)C]malathion dermal load (L), were used to examine the empirical relationship between Kp and L. The PBPK model was adapted from previously reported human biokinetic and PBPK models for malathion, fit to previously reported urinary excretion data after oral [(14)C]malathion intake by volunteers, and then augmented to incorporate a standard Kp approach to modeling dermal-uptake kinetics...
November 7, 2016: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
https://www.readbyqxmd.com/read/27818654/four-inducible-promoters-for-controlled-gene-expression-in-the-oleaginous-yeast-rhodotorula-toruloides
#14
Alexander M B Johns, John Love, Stephen J Aves
Rhodotorula (Rhodosporidium) toruloides is an oleaginous yeast with great biotechnological potential, capable of accumulating lipid up to 70% of its dry biomass, and of carotenoid biosynthesis. However, few molecular genetic tools are available for manipulation of this basidiomycete yeast and its high genomic GC content can make routine cloning difficult. We have developed plasmid vectors for transformation of R. toruloides which include elements for Saccharomyces cerevisiae in-yeast assembly; this method is robust to the assembly of GC-rich DNA and of large plasmids...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27818191/corticosteroids-for-the-management-of-severe-intracranial-hypertension-in-meningoencephalitis-caused-by-cryptococcus-gattii-a-case-report-and-review
#15
R-A Maciel, L-S Ferreira, F Wirth, P-D Rosa, M Aves, E Turra, L-Z Goldani
Immune reconstitution inflammatory syndrome in meningitis caused by Cryptococcus gattii in immunocompetent patients after initiation of antifungal therapy appears to be the result of paradoxical antifungal treatment-induced clinical deterioration due to improved local immune responses to cryptococcal organisms. Recent anecdotal reports have suggested a favorable clinical response to corticosteroids in select patients with C. gattii central nervous system (CNS) infections. In this report, we describe a 65-year-old patient with meningoencephalitis caused by C...
November 3, 2016: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/27814452/water-permeability-adjusts-resorption-in-lung-epithelia-to-increased-apical-surface-liquid-volumes
#16
Hanna Schmidt, Christiane Michel, Peter Braubach, Michael Fauler, Daniel Neubauer, Kristin E Thompson, Manfred Frick, Boris Mizaikoff, Paul Dietl, Oliver H Wittekindt
The apical surface liquid layer (ASL) covers the airways and forms a first line of defense against pathogens. Maintenance of ASL volume by airway epithelia is essential for maintaining lung function. The proteolytic activation of epithelial Na(+) channels (ENaC) is believed to be the dominating mechanism to cope with increases in ASL volumes. Alternative mechanisms, in particular increases in epithelial water permeability (Posm), have so far been regarded as rather less important. However, most studies mainly addressed immediate effects upon apical volume expansion (AVE) and increases in ASL...
November 4, 2016: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/27811707/taxonomic-revision-of-saffron-billed-sparrow-arremon-flavirostris-swainson-1838-aves-passerellidae-with-comments-on-its-holotype-and-type-locality
#17
Nelson Buainain, Guilherme Renzo Rocha Brito, Daniel Honorato Firme, Daniel Monteiro Figueira, Marcos A Raposo, Claydson Pinto De Assis
The Saffron-billed Sparrow (Arremon flavirostris) complex occurs in the undergrowth of deciduous woodlands and forests from the Andes of Bolivia and northern Argentina to Paraguay and southern, mid-western and interior eastern Brazil. Currently four subspecies are recognized: A. f. flavirostris, A. f. polionotus, A. f. devillii and A. f. dorbignii. We review the taxonomy of this complex by analyzing coloration and morphometrics of a series of 234 skins, and by comparing 101 sound recordings. Our results suggest that under both the Phylogenetic and Biological Species Concept, three species should be recognized in this complex: A...
October 26, 2016: Zootaxa
https://www.readbyqxmd.com/read/27794220/dna-interaction-antimicrobial-studies-of-newly-synthesized-copper-ii-complexes-with-2-amino-6-trifluoromethoxy-benzothiazole-schiff-base-ligands
#18
Aveli Rambabu, Marri Pradeep Kumar, Somapangu Tejaswi, Narendrula Vamsikrishna, Shivaraj
Four novel Schiff base ligands, L(1) (1-((E)-(6-(trifluoromethoxy)benzo[d]thiazol-2-ylimino)methyl)naphthalen-2-ol, C19H11F3N2O2S), L(2) (3-((E)-(6-(trifluoromethoxy)benzo[d]thiazol-2-ylimino)methyl)benzene-1,2-diol, C15H9F3N2O3S), L(3) (2-((E)-(6-(trifluoromethoxy)benzo[d]thiazol-2-ylimino)methyl)-5-methoxyphenol, C16H11F3N2O3S) and L(4) (2-((E)-(6-(trifluoromethoxy)benzo[d]thiazol-2-ylimino)methyl)-4-bromophenol, C15H8BrF3N2O2S) and their binary copper(II) complexes 1 [Cu(L(1))2], 2 [Cu(L(2))2], 3 [Cu(L(3))2] and 4 [Cu(L(4))2] have been synthesized and characterized by elemental analysis, (1)H NMR, (13)C NMR, ESI mass, FT-IR, ESR, UV-Visible, magnetic susceptibility, TGA, SEM and powder XRD studies...
October 24, 2016: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/27776434/codon-usage-bias-and-phylogenetic-analysis-of-mitochondrial-nd1-gene-in-pisces-aves-and-mammals
#19
Arif Uddin, Monisha Nath Choudhury, Supriyo Chakraborty
The mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 (MT-ND1) gene is a subunit of the respiratory chain complex I and involved in the first step of the electron transport chain of oxidative phosphorylation (OXPHOS). To understand the pattern of compositional properties, codon usage and expression level of mitochondrial ND1 genes in pisces, aves, and mammals, we used bioinformatic approaches as no work was reported earlier. In this study, a perl script was used for calculating nucleotide contents and different codon usage bias parameters...
October 24, 2016: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/27757952/evolutionary-innovation-and-diversification-of-carotenoid-based-pigmentation-in-finches
#20
Russell A Ligon, Richard K Simpson, Nicholas A Mason, Geoffrey E Hill, Kevin J McGraw
The ornaments used by animals to mediate social interactions are diverse, and by reconstructing their evolutionary pathways we can gain new insights into the mechanisms underlying ornamental innovation and variability. Here, we examine variation in plumage carotenoids among the true finches (Aves: Fringillidae) using biochemical and comparative phylogenetic analyses to reconstruct the evolutionary history of carotenoid states and evaluate competing models of carotenoid evolution. Our comparative analyses reveal that the most likely ancestor of finches used dietary carotenoids as yellow plumage colorants, and that the ability to metabolically modify dietary carotenoids into more complex pigments arose secondarily once finches began to use modified carotenoids to create red plumage...
October 19, 2016: Evolution; International Journal of Organic Evolution
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