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premature ejaculation

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https://www.readbyqxmd.com/read/29889310/the-effects-of-oxcarbazepine-levetiracetam-and-lamotrigine-on-semen-quality-sexual-function-and-sex-hormones-in-male-adults-with-epilepsy
#1
Dongmei Wu, Lang Chen, Fayuan Ji, Yang Si, Hongbin Sun
OBJECTIVE: To investigate the effects of antiepileptic drugs (AEDs; oxcarbazepine [OXC], levetiracetam [LEV], and lamotrigine [LTG]) on semen quality, sexual function, and sex hormones in male adults with epilepsy. METHODS: Individual treatment with OXC, LEV, or LTG was randomly assigned to 38 newly diagnosed male adult patients with epilepsy. Semen quality and sex hormones were measured before treatment and 6 months after taking the medicine. A questionnaire was administered using the International Index of Erectile Function Scale-5 and the Premature Ejaculation Diagnostic Tool Self-Assessment Scale to evaluate sexual function, followed by an analysis of the comparison between the treated patients and healthy volunteers (healthy controls) as well as the changes and differences between the patients themselves before and after treatment...
June 11, 2018: Epilepsia
https://www.readbyqxmd.com/read/29884323/functional-insights-into-the-role-of-seminal-plasma-proteins-on-sperm-motility-of-buffalo
#2
Viviane Maria Codognoto, Paulo Henrique Yamada, Rúbia Alves Schmith, Felipe Rydygier de Ruediger, Caroline Scott, Patrícia de Faria Lainetti, Suzane Brochine, Camila de Paula Freitas-Dell'Aqua, Fabiana Ferreira de Souza, Eunice Oba
The objective of the present study was to describe the proteins from the seminal plasma of buffalo and correlate these proteins with sperm motility. Ejaculates from sixteen Murrah buffalo were used. Semen collection was performed by electroejaculation, and the ejaculate was evaluated by macroscopic (volume) and microscopic analysis (subjective motility and vigor, as well as sperm concentration). After the analysis, the samples were centrifuged (800g for 10 min and 10,000 for 30 min at 4 °C), and the supernatant (seminal plasma) was used to determine total protein concentration by the Bradford method...
June 2, 2018: Animal Reproduction Science
https://www.readbyqxmd.com/read/29872385/central-neural-correlates-during-inhibitory-control-in-lifelong-premature-ejaculation-patients
#3
Xuejuan Yang, Ming Gao, Lan Zhang, Lin Liu, Peng Liu, Jinbo Sun, Yibin Xi, Hong Yin, Wei Qin
Lifelong premature ejaculation (LPE) is a common male sexual dysfunction. Lack of active control for rapid ejaculation brought great distress to sexual harmony and even fertility. Previous neurophysiology studies revealed an ejaculation-related control mechanism in the brain. However, it remains unclear whether this inhibitory network is altered in LPE patients. The present study investigated the central inhibitory network function of LPE patients by using stop signal task (SST)-related functional magnetic resonance imaging (fMRI) and resting-state functional connectivity (FC) analysis...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29862208/a-randomized-double-blind-placebo-controlled-trial-to-assess-the-effect-of-tamarind-seed-in-premature-ejaculation
#4
Abdulla Homayuonfar, Alireza Aminsharifi, Alireza Salehi, Ali Sahraian, Shadab Dehshari, Mohsen Bahrami
Background: This randomized clinical trial was aimed to evaluate the effect of oral use of tamarind seed powder as an herbal product in patients affected by premature ejaculation (PE). Materials and Methods: In this study, 75 patients randomized in tamarind group (25 patients received daily 130 mg tamarind seed powder), paroxetine group (25 patients received daily 20 mg paroxetine), and placebo group (25 patients). Patients received the treatment regimen for 4 weeks...
2018: Advanced Biomedical Research
https://www.readbyqxmd.com/read/29850442/the-efficacy-and-safety-of-on-demand-tramadol-and-paroxetine-use-in-treatment-of-life-long-premature-ejaculation-a-randomized-double-blind-placebo-controlled-clinical-trial
#5
Ali Hamidi-Madani, Reza Motiee, Gholamreza Mokhtari, Hamidreza Nasseh, Samaneh Esmaeili, Ehsan Kazemnezhad
Background: Several medical therapies have been proposed for the treatment of premature ejaculation (PE). Paroxetine and tramadol were both reported to be effective in treatment of PE. In this study, the therapeutic effects of tramadol, paroxetine and placebo were compared in treatment of primary PE. Methods: In this randomized, double-blind, placebo-controlled clinical trial, 150 patients were divided into 3 groups. One group was treated with tramadol 50 mg ondemand, the other group took paroxetine 20 mg on-demand and the third group was treated with placebo...
January 2018: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/29803639/premature-ejaculation-among-italian-men-prevalence-and-clinical-correlates-from-an-observational-non-interventional-cross-sectional-epidemiological-study-iper
#6
Paolo Verze, Davide Arcaniolo, Alessandro Palmieri, Tommaso Cai, Roberto La Rocca, Marco Franco, Luca Venturino, Marco De Sio, Vincenzo Mirone
INTRODUCTION: There is a great variability in the prevalence of premature ejaculation (PE) worldwide and only few data are available about the Italian population. AIM: To determine the prevalence of PE in the adult male population in Italy. METHODS: Adult men 18 to 80 years old who were sexually active were randomly sampled from patient lists of general practitioners in Italy and were included in this observational, non-interventional, cross-sectional epidemiologic study from January to July 2015...
May 23, 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29751700/-research-progress-of-tibetan-medicine-zha-xun
#7
Ming-Ming Zhao, Rui Gu, Jiu-Yu Fan, Yong Zeng, Yun Cao, Wen-Qian Wang, Shi-Hong Zhong, Peng Mi
Zha-xun is widely used in Tibetan medicine and is also an international traditional medicine. This article would summarize the use status and research progress of Zha-xun by various ethnic groups all over the world, and the results show that it has various synonyms but most of them imply its most characteristic feature-outflow from the rock; Zha-xun resources are distributed in various places of the world, and its bearing spots are closely related to the geological structure; there are sharp arguments on the origins of Zha-xun, mainly including the minerals origin, biological fossils origin, biological origin, etc...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29736066/prevalence-and-correlates-of-sexual-dysfunction-in-male-patients-with-alcohol-dependence-syndrome-a-cross-sectional-study
#8
Deepak Koyilerian Prabhakaran, A Nisha, P Joseph Varghese
Background: Contrary to the popular belief concerning the aphrodisiac effects of alcohol, there exists scientific evidence which conclude on sexual dysfunction caused by chronic alcohol use. There is a dearth of studies from India. Aim: The aim is to estimate the prevalence and correlates of sexual dysfunction in alcohol-dependent patients and to explore the association between sexual dysfunction and various alcohol-related variables. Materials and Methods: The study employed a cross-sectional descriptive design and recruited 84 male patients admitted for de-addiction in a tertiary care center...
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29733030/enduring-sexual-dysfunction-after-treatment-with-antidepressants-5%C3%AE-reductase-inhibitors-and-isotretinoin-300-cases
#9
David Healy, Joanna Le Noury, Derelie Mangin
OBJECTIVE: To investigate clinical reports of post-SSRI sexual dysfunction (PSSD), post-finasteride syndrome (PFS) and enduring sexual dysfunction following isotretinoin. METHODS: Data from RxISK.org, a global adverse event reporting website, have been used to establish the clinical features, demographic details and clinical trajectories of syndromes of persistent sexual difficulties following three superficially different treatment modalities.RESULTSWe report on 300 cases of enduring sexual dysfunction from 37 countries following 14 different drugs comprised of serotonin reuptake inhibiting antidepressants, 5α-reductase inhibitors and isotretinoin...
May 1, 2018: International Journal of Risk & Safety in Medicine
https://www.readbyqxmd.com/read/29727393/sexual-function-in-young-individuals-with-multiple-sclerosis-does-disability-matter
#10
Rocco Salvatore Calabrò, Margherita Russo, Vincenzo Dattola, Rosaria De Luca, Antonino Leo, Jacopo Grisolaghi, Placido Bramanti, Fabrizio Quattrini
INTRODUCTION: Studies on the prevalence of sexual dysfunction (SD) in multiple sclerosis (MS) have shown that 40% to 80% of women and 50% to 90% of men have had sexual complaints. Sexual function is often disregarded during consultation with healthcare professionals, and SD is frequently underdiagnosed. The aim of this study was to investigate the prevalence of SD and its relationship to sociodemographic and disease-related factors, with regard to disability state, in a hospital cohort of MS patients, by using a semistructured interview...
June 2018: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/29681052/is-there-any-association-between-regular-physical-activity-and-ejaculation-time
#11
Yildiray Yildiz, Muhammet Fatih Kilinc, Omer Gokhan Doluoglu
PURPOSE: Premature ejaculation (PE) is a prevalent disorder in males leading to sequelae such as lack of self-confidence,anxiety, depression and unsatisfactory intercourse for these men and their partners. The aim of this study was to evaluate the relationship between ejaculation and physical activity. MATERIALS AND METHODS: Group 1 comprised 112 participants who took regular physical activity and Group 2 comprised 126 participants with a sedentary lifestyle. The participants were 18-45 years old, same ethnic origin, insame location and had regular sexual activity for at least 6 months...
April 19, 2018: Urology Journal
https://www.readbyqxmd.com/read/29608897/uses-of-fluoxetine-in-nociceptive-pain-management-a-literature-overview
#12
REVIEW
Ahmed Barakat, Mostafa M Hamdy, Mohamed M Elbadr
Fluoxetine is one of the top ten prescribed antidepressants. Other therapeutic applications were approved for fluoxetine including, anxiety disorders, bulimia nervosa, and premature ejaculation. However, the role of fluoxetine in nociceptive pain management is still unclear. In this review, we discuss an overview of five possible roles of fluoxetine in pain management: intrinsic antinociceptive effect, enhancement of acute opioid analgesia, attenuation of tolerance development to opioid analgesia, attenuation of dependence development and abstinence syndrome, and attenuation of opioid induced hyperalgesia...
June 15, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29600795/no-effect-of-abstinence-time-on-nerve-electrophysiological-test-in-premature-ejaculation-patients
#13
Bai-Bing Yang, Jia-Dong Xia, Zhi-Wei Hong, Zheng Zhang, You-Feng Han, Yun Chen, Yu-Tian Dai
The nerve electrophysiological tests may differentiate the treatment of primary premature ejaculation (PPE) in our previous studies. However, no study verifies if the results will be affected by abstinence time. From January to December in 2016, fifty PPE patients ejaculated within 2 min and 28 control subjects were enrolled. The nerve electrophysiological tests, including dorsal nerve somatosensory evoked potential (DNSEP), glans penis somatosensory evoked potential (GPSEP), and penile sympathetic skin response (PSSR), were recorded before and immediately after ejaculation...
March 30, 2018: Asian Journal of Andrology
https://www.readbyqxmd.com/read/29564281/a-case-report-of-over-the-counter-codeine-dependence-as-consequence-of-self-medication-for-premature-ejaculation
#14
Sethulakshmi Sreevalsam Anil, Badr Ratnakaran, Nisha Suresh
Over-the-counter (OTC) opioid abuse, including codeine, has been a growing problem around the world. Although the majority of the abusers use it for recreational purposes, many become dependent on it after having used it a medication for pain or cough. We present a case of codeine dependence where the initial prescribed use had been as a cough medication, but the subsequent abuse of it occurred the following self-medication for premature ejaculation. There is growing need for awareness among doctors and pharmacists of OTC abuse of opioids and for preventive interventions such as restricting supply, audit of pharmacies, training pharmacists, and counter staff and dispensing knowledge about proper use of opioid-containing medications to patients...
October 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29556396/longer-trinucleotide-repeats-of-androgen-receptor-are-associated-with-higher-testosterone-and-low-oxytocin-levels-in-diabetic-premature-ejaculatory-dysfunction-patients
#15
Haroon Latif Khan, Shahzad Bhatti, Sana Abbas, Yousaf Latif Khan, Rosa Maria Marquez Gonzalez, Muhammad Aslamkhan, Gerardo Rodriguez Gonzalez, Hikmet Hakan Aydin
Background: Despite its worldwide high occurrence, the obscurity regarding the description, epidemiology and management of premature ejaculation remains provocative. It is well established that male premature ejaculatory dysfunction is an increasing problem due to spontaneous ejaculation across a variety of general and clinical subjects. The main goal of this study was to determine the relationships between trinucleotide repeats of the androgen receptor (AR), sex steroids, and pituitary hormones with sexual function in men with type 2 diabetes mellitus (DM) and reported with acquired premature ejaculation (PE)...
2018: Basic and Clinical Andrology
https://www.readbyqxmd.com/read/29532805/sexual-dysfunction-and-male-infertility
#16
REVIEW
Francesco Lotti, Mario Maggi
Infertility affects up to 12% of all men, and sexual dysfunction occurs frequently in men of reproductive age, causing infertility in some instances. In infertile men, hypoactive sexual desire and lack of sexual satisfaction are the most prevalent types of sexual dysfunction, ranging from 8.9% to 68.7%. Erectile dysfunction and/or premature ejaculation, evaluated with validated tools, have a prevalence of one in six infertile men, and orgasmic dysfunction has a prevalence of one in ten infertile men. In addition, infertile men can experience a heavy psychological burden...
May 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29527702/efficacy-and-safety-of-daily-use-of-tadalafil-in-treatment-of-patients-with-premature-ejaculation-a-randomised-placebo-controlled-clinical-trial
#17
M Abu El-Hamd
The study aimed to evaluate the efficacy and safety of the once-daily use of 5 mg tadalafil in the treatment of patients with premature ejaculation (PE). In a single-blind placebo-controlled clinical study, it was carried out on 100 patients with PE. All patients were randomised equally divided into two groups (50 patients each). Group 1 was given placebo in the form of oral multivitamin tablet once a day for 6 weeks. Group 2 was given 5 mg tadalafil once a day for 6 weeks. All patients were asked to complete Arabic Index of Premature Ejaculation (AIPE) before and after the treatment...
March 12, 2018: Andrologia
https://www.readbyqxmd.com/read/29523489/male-sexual-quality-of-life-is-maintained-satisfactorily-throughout-life-in-the-amazon-rainforest
#18
Thiago Teixeira, Maira Nazima, Jorge Hallak
INTRODUCTION: The Amazon Rainforest is a cradle of biodiversity, where different ethnic groups have specific sexual habits. AIMS: To define the average sexual quality of life of Amazonian men 18 to 69 years old, evaluate the influence of aging on their sexual function, and calculate the prevalence of premature ejaculation, delayed ejaculation, and hypoactive sexual desire disorder. METHODS: A cross-sectional quantitative probability sample study was performed with a demographically representative population (N = 385), with data collected privately at participants' houses, including men who had been sexually active for a minimum of 6 months...
June 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29523476/health-related-lifestyle-factors-and-sexual-dysfunction-a-meta-analysis-of-population-based-research
#19
REVIEW
Mark S Allen, Emma E Walter
BACKGROUND: Sexual dysfunction is a common problem among men and women and is associated with negative individual functioning, relationship difficulties, and lower quality of life. AIM: To determine the magnitude of associations between 6 health-related lifestyle factors (cigarette smoking, alcohol intake, physical activity, diet, caffeine, and cannabis use) and 3 common sexual dysfunctions (erectile dysfunction, premature ejaculation, and female sexual dysfunction)...
April 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29520842/mapping-the-landscape-of-urology-a-new-media-based-cross-sectional-analysis-of-public-versus-academic-interest
#20
Hendrik Borgmann, Johannes Salem, Martin Baunacke, Katharina Boehm, Christer Groeben, Marianne Schmid, Fabian P Siegel, Johannes Huber
OBJECTIVES: To quantify public and academic interest in the urological field using a novel new media-based methodology. METHODS: We systematically measured public and academic interest in 56 urological keywords and combined in nine subspecialties. Public interest was quantified as video views on YouTube. Academic interest was quantified as article citations using Microsoft Academic Search. The public-to-academic interest ratio was calculated for a comparison of subspecialties as well as for diseases and treatments...
May 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
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