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https://www.readbyqxmd.com/read/27613452/empty-nose-syndrome-and-atrophic-rhinitis
#1
Kena Shah, Juan Guarderas, Guha Krishnaswamy
No abstract text is available yet for this article.
September 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27574563/update-on-diagnostic-value-of-breath-test-in-gastrointestinal-and-liver-diseases
#2
REVIEW
Imran Siddiqui, Sibtain Ahmed, Shahab Abid
In the field of gastroenterology, breath tests (BTs) are used intermittently as diagnostic tools that allow indirect, non-invasive and relatively less cumbersome evaluation of several disorders by simply quantifying the appearance in exhaled breath of a metabolite of a specific substrate administered. The aim of this review is to have an insight into the principles, methods of analysis and performance parameters of various hydrogen, methane and carbon BTs which are available for diagnosing gastrointestinal disorders such as Helicobacter pylori infection, small intestinal bacterial overgrowth, and carbohydrate malabsorption...
August 15, 2016: World Journal of Gastrointestinal Pathophysiology
https://www.readbyqxmd.com/read/27559978/safety-and-feasibility-of-the-rhinochill-immediate-transnasal-evaporative-cooling-device-during-out-of-hospital-cardiopulmonary-resuscitation-a-single-center-observational-study
#3
Marie-Sophie Grave, Fritz Sterz, Alexander Nürnberger, Stergios Fykatas, Mathias Gatterbauer, Albert Friedrich Stättermayer, Andreas Zajicek, Reinhard Malzer, Dieter Sebald, Raphael van Tulder
We investigated feasibility and safety of the RhinoChill (RC) transnasal cooling system initiated before achieving a protected airway during cardiopulmonary resuscitation (CPR) in a prehospital setting.In out-of-hospital cardiac arrest (OHCA), transnasal evaporative cooling was initiated during CPR, before a protected airway was established and continued until either the patient was declared dead, standard institutional systemic cooling methods were implemented or cooling supply was empty. Patients were monitored throughout the hypothermia period until either death or hospital discharge...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27557473/the-empty-nose-syndrome-6-item-questionnaire-ens6q-a-validated-6-item-questionnaire-as-a-diagnostic-aid-for-empty-nose-syndrome-patients
#4
Nathalia Velasquez, Andrew Thamboo, Al-Rahim R Habib, Zhenxiao Huang, Jayakar V Nayak
BACKGROUND: Empty nose syndrome (ENS) is considered an acquired condition that remains difficult to diagnose objectively. Defining specific symptoms that can be reliably associated with this disorder would be essential to identifying possible ENS patients. We sought to validate an ENS-specific, 6-item questionnaire as an adjunct to the standard Sino-Nasal Outcome Test 22 (SNOT-22) questionnaire to discriminate patients suspected of having ENS. METHODS: The Empty Nose Syndrome 6-item Questionnaire (ENS6Q) paired 6 common ENS symptoms (nasal suffocation, nasal burning, nasal openness, crusting, dryness, and impaired air sensation through nasal cavities) with testing on 75 patients divided in 3 patient cohorts: ENS; chronic rhinosinusitis without polyposis; and healthy controls...
August 24, 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27409044/distinguishing-computed-tomography-findings-in-patients-with-empty-nose-syndrome
#5
Andrew Thamboo, Nathalia Velasquez, Noel Ayoub, Jayakar V Nayak
BACKGROUND: Given the lack of basic diagnostic criteria for empty nose syndrome (ENS), we sought to define whether consistent radiographic characteristics could be identified to aid in the development of such criteria. METHODS: Computed tomography (CT) scans were collected from 65 patients diagnosed with ENS, patients with a history of submucosal inferior turbinate reduction (ITR) without ENS, and patients without a history of sinonasal procedures. Measurements were taken at the level of the nasolacrimal duct, including the inferior turbinate (IT) mucosal thickness, and the widest distances between septum-IT, nasal floor-IT, lateral nasal wall-IT, and septum-lateral nasal wall...
July 13, 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27377086/the-relationship-of-enuresis-nocturna-and-adenoid-hypertrophy
#6
Muhsin Balaban, Alper Aktas, Cuneyd Sevinc, Ugur Yucetas
OBJECTIVES: This study was organized to assess the relationship of enuresis nocturna (EN) and upper airway obstruction (UAO) in children. MATERIAL AND METHODS: This study was multi-centrically and prospectively designed including 79 children who presented to a urology clinic with symptoms of EN between January 2013 and February 2014. Sixty-four age-matched children with no history of urological complaints were randomly recruited from children admitted to a pediatric clinic as a control group...
2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/27368609/follow-your-nose-leaf-odour-as-an-important-foraging-cue-for-mammalian-herbivores
#7
Rebecca S Stutz, Peter B Banks, Nicholas Proschogo, Clare McArthur
Studies of odour-driven foraging by mammals focus on attractant cues emitted by flowers, fruits, and fungi. Yet, the leaves of many plant species worldwide produce odour, which could act as a cue for foraging mammalian herbivores. Leaf odour may thus improve foraging efficiency for such herbivores in many ecosystems by reducing search time, particularly but not only, for plants that are visually obscured. We tested the use of leaf odour by a free-ranging mammalian browser, the swamp wallaby (Wallabia bicolor) to find and browse palatable tree seedlings (Eucalyptus pilularis)...
November 2016: Oecologia
https://www.readbyqxmd.com/read/27213937/experimental-assessment-of-mouse-sociability-using-an-automated-image-processing-approach
#8
Frency Varghese, Jessica A Burket, Andrew D Benson, Stephen I Deutsch, Christian W Zemlin
Mouse is the preferred model organism for testing drugs designed to increase sociability. We present a method to quantify mouse sociability in which the test mouse is placed in a standardized apparatus and relevant behaviors are assessed in three different sessions (called session I, II, and III). The apparatus has three compartments (see Figure 1), the left and right compartments contain an inverted cup which can house a mouse (called "stimulus mouse"). In session I, the test mouse is placed in the cage and its mobility is characterized by the number of transitions made between compartments...
2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27191684/optimizing-stimulation-in-a-case-of-facial-pain-through-cross-talk-of-peripheral-and-central-leads-a-case-report
#9
W Porter McRoberts
OBJECTIVES: To describe inter-lead (cross-talk) stimulation between a trigeminal nerve lead and a cervical epidural lead for the treatment of facial pain in a 69-year-old patient with empty nose syndrome. MATERIALS AND METHODS: A trial implant was performed with a peripheral V2 trigeminal lead and a C1-C2 lead in cross-talk configuration. During permanent implant, the V2 lead was placed uneventfully while the central lead could only be advanced to C3-C4. RESULTS: During the trial, pain decreased by 70%...
May 18, 2016: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/27150141/pharmacological-profile-of-gpd-1116-an-inhibitor-of-phosphodiesterase-4
#10
Takashi Nose, Miwa Kondo, Masashi Shimizu, Hiroki Hamura, Yusuke Yamaguchi, Takako Sekine, Kouki Ishitani
We have previously reported that GPD-1116, an inhibitor of phosphodiesterase (PDE) 4, exhibits anti-inflammatory effects in a model of cigarette smoke-induced emphysema in senescence-accelerated P1 mice. In the present study, we further characterized the pharmacological profile of GPD-1116 in several experiments in vitro and in vivo. GPD-1116 and its metabolite GPD-1133 predominantly inhibited not only human PDE4, but also human PDE1 in vitro. Moreover, GPD-1116 was effective in several disease models in animals, including acute lung injury, chronic obstructive pulmonary disease (COPD), asthma and pulmonary hypertension; the effective doses of GPD-1116 were estimated to be 0...
2016: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/27143707/%C3%A3-tricalcium-phosphate-implants-in-the-surgical-treatment-of-empty-nose-syndrome
#11
Pierre-Louis Bastier, Sylvestre Fierens, Sylvain Champel, Alix Ribadeau-Dumas, Ludovic de Gabory
The objective of this study was to assess the efficacy and morbidity of a β-tricalcium phosphate implant in the treatment of empty nose syndrome after turbinectomy. Only patients with a history of inferior turbinectomy and a complaint of permanent paradoxical nasal obstruction were included. β-Tricalcium phosphate ceramic implants were implanted under the mucoperiosteal plane of the lateral nasal wall to replace the head of the inferior turbinate. Symptoms and quality of life were assessed by 2 questionnaires: the Nasal Obstruction Symptom Evaluation and Rhinosinusitis Quality of Life...
September 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/26692010/correlation-between-remnant-inferior-turbinate-volume-and-symptom-severity-of-empty-nose-syndrome
#12
Hye Ran Hong, Yong Ju Jang
OBJECTIVES/HYPOTHESIS: Empty nose syndrome (ENS) is an iatrogenic disorder caused by turbinate reduction procedures, which results in considerable nasal dysfunction and severely impaired quality of life. However, there is a lack of data that explains the relationship between the degree of turbinate reduction and subjective symptoms. The aim of this study was to evaluate the effects of remnant inferior turbinate volume on symptom severity. STUDY DESIGN: We retrospectively analyzed data from 34 patients who were diagnosed with ENS...
June 2016: Laryngoscope
https://www.readbyqxmd.com/read/26667794/evaluation-of-depression-and-anxiety-in-empty-nose-syndrome-after-surgical-treatment
#13
Ta-Jen Lee, Chia-Hsiang Fu, Ching-Lung Wu, Yuan-Yun Tam, Chi-Che Huang, Po-Hung Chang, Yi-Wei Chen, Meng-Hsiu Wu
OBJECTIVES/HYPOTHESIS: Empty nose syndrome (ENS) is often associated with psychological symptoms. With the absence of psychiatric instruments utilized in the current literature, the assessment of psychological disorder is limited, and the effectiveness of surgical intervention in improving such disorders in ENS are not well understood. The aim of this study was to evaluate the change in depression and anxiety before and after surgical treatment for ENS STUDY DESIGN: Prospective cohort study in a tertiary medical center...
June 2016: Laryngoscope
https://www.readbyqxmd.com/read/26535824/inferior-turbinate-augmentation-with-auricular-cartilage-for-the-treatment-of-empty-nose-syndrome
#14
Angela A Chang, Deborah Watson
Empty nose syndrome (ENS) is a potential complication of excessive resection of turbinate tissue. Patients with ENS complain of nasal obstruction despite a widely patent nasal cavity. Various implants, including autologous bone and biomaterials, have been used to reduce the width of the nasal cavity. Implantation of these grafts, however, has been limited by extrusion, infection, and resorption. We introduce a novel surgical technique that uses autologous auricular cartilage to augment the turbinate and to restore the natural airflow patterns of the nasal cavity...
October 2015: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/26439547/op-6-intragastric-pressure-measurement-during-nutrient-intake-a-novel-minimally-invasive-method-to-measure-gastric-accommodation-in-functional-dyspepsia
#15
F Carbone, J Tack, I Hofmann
BACKGROUND: Functional dyspepsia (FD) in pediatrics is defined as the presence of upper abdominal symptoms for at least 2 months in the absence of organic or metabolic disease likely to explain the symptoms. The main proposed pathophysiological mechanisms are visceral hypersensitivity,impaired gastric accommodation (GA) and delayed gastric emptying. At present, the gastric barostat is the gold standard to measure GA. However, this procedure is perceived as very invasive and it might alter the normal gastric physiology...
October 2015: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/26427129/-submucosal-partial-turbinectomy-spt-preceding-an-endoscopic-sinus-surgery-ess-procedure
#16
Tomohisa Hirai, Noriyuki Fukushima, Nobuyuki Miyahara, Ayako Miyoshi, Masahiko Ariki
Preceding a endoscopic sinus surgery (ESS), we have proposed performing a submucosal partial-turbinectomy (SPT) which removes a part of the inferior nasal concha bone attached to maxillary sinus with an antrostomy. By this method, we could not only make a large antrostomy but also obtain good maneuverability by opening the middle nasal meatus in ESS. We performed SPT preceding ESS in 140 cases (261 sides) between January 2012 and June 2014. The stenosis rates of the middle nasal meatus were 14.2% (37 sides from 261 sides) in one month, 7...
July 2015: Nihon Jibiinkoka Gakkai Kaiho
https://www.readbyqxmd.com/read/26388989/the-expansion-of-autologous-adipose-derived-stem-cells-in-vitro-for-the-functional-reconstruction-of-nasal-mucosal-tissue
#17
Xiao Xu, Liang Li, Cheng Wang, Yang Liu, Chong Chen, Junling Yan, Hong Ding, Su-Yang Tang
BACKGROUND: I t is established that adipose-derived stem cells (ADSCs) produce and secrete cytokines/growth factors that antagonize mucosal injury. However, the exact molecular basis underlying the treatment effects exerted by ADSCs is ill understood, and whether ADSCs cooperate with adipose tissue particles to improve mucosal function in patients with empty nose syndrome (ENS) has not been explored. We investigated the impact of ADSCs on nasal mucosa, the associated mechanisms, and their use in the treatment of patients with ENS...
2015: Cell & Bioscience
https://www.readbyqxmd.com/read/26332403/inferior-turbinate-reconstruction-using-porcine-small-intestine-submucosal-xenograft-demonstrates-improved-quality-of-life-outcomes-in-patients-with-empty-nose-syndrome
#18
Nathalia Velasquez, Zhenxiao Huang, Ian M Humphreys, Jayakar V Nayak
BACKGROUND: We describe the surgical technique for use of small intestine submucosal (SIS) xenograft implant for inferior turbinate reconstruction and report our early results in a pilot case series of patients suffering from symptoms consistent with empty nose syndrome (ENS). METHODS: We report an observational prospective cohort study of ENS patients undergoing inferior turbinate reconstruction using porcine SIS xenograft. Effects of the procedure on quality of life (QOL) were assessed through serial 25-item Sino-Nasal Outcome Test (SNOT-25) scores and analyzed by 1-way analysis of variance (ANOVA) between the initial visit and 1, 4, and 12 weeks after surgery...
November 2015: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/26146581/endoscopic-modified-medial-maxillectomy-for-resection-of-an-inverted-papilloma-originating-from-the-entire-circumference-of-the-maxillary-sinus
#19
Kota Wada, Takashi Ishigaki, Yutaro Ida, Yuki Yamada, Sachiko Hosono, Hideo Edamatsu
For treatment of a sinonasal inverted papilloma (IP), it is essential to have a definite diagnosis, to identify its origin by computed tomography (CT) and magnetic resonance imaging (MRI), and to select the appropriate surgical approach based on the staging system proposed by Krouse. Recently, a new surgical approach named endoscopic modified medial maxillectomy (EMMM) was proposed. This approach can preserve the inferior turbinate and nasolacrimal duct. We successfully treated sinonasal IP with EMMM in a 71-year-old female patient...
2015: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/26093262/the-effects-of-prenatal-pcbs-on-adult-social-behavior-in-rats
#20
Michael P Reilly, Connor D Weeks, Viktoria Y Topper, Lindsay M Thompson, David Crews, Andrea C Gore
Endocrine disrupting chemical (EDC) exposures during critical periods of development may influence neuronal development and the manifestation of sexually dimorphic sociability and social novelty behaviors in adulthood. In this study, we assessed the effects of gestational exposure to PCBs on the social behavior of males and females later in adulthood. A weakly estrogenic PCB mixture, Aroclor 1221 (A1221, 0.5 or 1mg/kg) was administered to pregnant Sprague-Dawley rat dams. Both a positive control (estradiol benzoate; EB, 50μg/kg) and negative control (dimethylsulfoxide; DMSO in sesame oil vehicle) were similarly administered to separate sets of dams...
July 2015: Hormones and Behavior
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