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femur fractures

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https://www.readbyqxmd.com/read/29451942/incidence-of-and-risk-factors-for-knee-collateral-ligament-injuries-with-proximal-tibia-fractures-a-study-of-32-441-patients
#1
Andre M Samuel, Pablo J Diaz-Collado, Lauren K Szolomayer, Daniel H Wiznia, Wayne W Chan, Adam M Lukasiewicz, Bryce A Basques, Daniel D Bohl, Jonathan N Grauer
Proximal tibia fractures are associated with concurrent collateral ligament injuries. Failure to recognize these injuries may lead to chronic knee instability. The purpose of this study was to identify risk factors for concurrent collateral ligament injuries with proximal tibia fractures and their association with inpatient outcomes. A total of 32,441 patients with proximal tibia fractures were identified in the 2011-2012 National Trauma Data Bank. A total of 1445 (4.5%) had collateral ligament injuries, 794 (2...
February 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29447441/design-factors-of-femur-fracture-fixation-plates-made-of-shape-memory-alloy-based-on-the-taguchi-method-by-finite-element-analysis
#2
Cheolwoong Ko, Mikyung Yang, Taemin Byun, Sang-Wook Lee
This study proposed a way to design femur fracture fixation plates made of shape memory alloy based on CT (Computed Tomography) images of Korean cadaveric femurs. To this end, 3 major design factors of femur fracture fixation plates (circumference angle, thickness, and inner diameter) were selected based on the contact pressure when a femur fracture fixation plate was applied to a cylinder model using the Taguchi Method. Then the effects of the design factors were analyzed. It was shown that the design factors were statistically significant at a level of p=0...
February 15, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29444703/whole-bone-testing-in-small-animals-systematic-characterization-of-the-mechanical-properties-of-different-rodent-bones-available-for-rat-fracture-models
#3
Peter M Prodinger, Peter Foehr, Dominik Bürklein, Oliver Bissinger, Hakan Pilge, Kilian Kreutzer, Rüdiger von Eisenhart-Rothe, Thomas Tischer
OBJECTIVES: Rat fracture models are extensively used to characterize normal and pathological bone healing. Despite, systematic research on inter- and intra-individual differences of common rat bones examined is surprisingly not available. Thus, we studied the biomechanical behaviour and radiological characteristics of the humerus, the tibia and the femur of the male Wistar rat-all of which are potentially available in the experimental situation-to identify useful or detrimental biomechanical properties of each bone and to facilitate sample size calculations...
February 14, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29443832/one-barrel-microsurgical-fibula-flap-for-reconstruction-of-large-defects-of-the-femur
#4
Jung Eun Lee, Min Bom Kim, Do Hwan Han, Sung Hee Pyo, Young Ho Lee
Various methods for reconstructing large femur bone defects after tumor resection have been introduced. In this study, we reviewed the clinical outcomes of using a 1-barrel free vascularized fibular graft (FVFG) protected by a lateral locking plate for large femoral defects not involving the knee joint.Between August 2007 and August 2013, we treated 7 patients with large femoral bone defects after tumor resection. The mean age of the patients was 19 years (range, 12-36 years), and 3 were women. All defects were free of infection before the procedure...
February 13, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29442350/occult-phosphaturic-mesenchymal-tumor-of-femur-cortex-causing-oncogenic-osteomalacia-diagnostic-challenges-and-clinical-outcomes
#5
Deep Dutta, Raghuvansh Kumar Pandey, Rakhee Gogoi, Nagender Solanki, Renu Madan, Anupam Mondal, Shruti Dogra, Pradeep Thapa
BACKGROUND: Tumor induced osteomalacia (TIO) are extremely rare paraneoplastic syndrome with less than 300 reported cases. This report highlights the pitfalls and challenges in diagnosing and localizing TIO in patients with refractory and resistant osteomalacia. PATIENT AND METHODS: 41- year gentleman with 4-year history of musculoskeletal weakness and pathologic fractures presented in wheelchair bound incapacitated state of 1-year duration. Investigations were significant for severe hypophosphatemia, severe phosphaturia, normal serum calcium, reduced 1,25-dihydroxy vitamin-D, elevated ALP, elevated intact parathyroid hormone (iPTH), and pseudo-fractures involving pelvis and bilateral femur...
February 14, 2018: Endokrynologia Polska
https://www.readbyqxmd.com/read/29440906/percutaneous-autologous-bone-marrow-transplantation-for-the-treatment-of-delayed-union-of-limb-bone-in-children
#6
Jun Wu, Hongxi Guo, Xing Liu, Ming Li, Yujiang Cao, Xiangyang Qu, Hai Zhou, Liuqi Weng
Background and purpose: Percutaneous autologous bone marrow transplantation (PABMT) is a minimally invasive therapeutic strategy for the treatment of delayed bone union in adults, which has been confirmed by many studies. However, there is no report on PABMT application in pediatric orthopedic surgery. The aim of this article was to analyze the therapeutic effect of PABMT in children with delayed union of limb bone and its influence in relation to delayed bone union therapy, transplantation period, patients' sex, fracture location, and fracture fixation...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29440477/the-man-with-two-broken-hips-neck-of-femur-fracture-with-previous-girdlestone-arthroplasty
#7
Nainesha Kulkarni, Abhishek Chitnis
No abstract text is available yet for this article.
February 12, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29438824/low-bone-toughness-in-the-tallyho-model-of-juvenile-type-2-diabetes-does-not-worsen-with-age
#8
Amy Creecy, Sasidhar Uppuganti, Mustafa Unal, R Clay Bunn, Paul Voziyan, Jeffry S Nyman
Fracture risk increases as type 2 diabetes (T2D) progresses. With the rising incidence of T2D, in particular early-onset T2D, a representative pre-clinical model is needed to study mechanisms for treating or preventing diabetic bone disease. Towards that goal, we hypothesized that fracture resistance of bone from diabetic TallyHO mice decreases as the duration of diabetes increases. Femurs and lumbar vertebrae were harvested from male, TallyHO mice and male, non-diabetic SWR/J mice at 16 weeks (n ≥ 12 per strain) and 34 weeks (n ≥ 13 per strain) of age...
February 10, 2018: Bone
https://www.readbyqxmd.com/read/29437637/altered-expression-of-microrna-during-fracture-healing-in-diabetic-rats
#9
S Takahara, S Y Lee, T Iwakura, K Oe, T Fukui, E Okumachi, T Waki, M Arakura, Y Sakai, K Nishida, R Kuroda, T Niikura
OBJECTIVES: Diabetes mellitus (DM) is known to impair fracture healing. Increasing evidence suggests that some microRNA (miRNA) is involved in the pathophysiology of diabetes and its complications. We hypothesized that the functions of miRNA and changes to their patterns of expression may be implicated in the pathogenesis of impaired fracture healing in DM. METHODS: Closed transverse fractures were created in the femurs of 116 rats, with half assigned to the DM group and half assigned to the control group...
February 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29435177/prostate-selective-%C3%AE-antagonists-increase-fracture-risk-in-prostate-cancer-patients-with-and-without-a-history-of-androgen-deprivation-therapy-a-nationwide-population-based-study
#10
Wei-Heng Kao, Chang-Fu Kuo, I-Jun Chou, Lai-Chu See, Wen-Kuan Huang, Meng-Jiun Chiou, Weiya Zhang, Michael Doherty, Chun-Chieh Wang, Jun-Te Hsu, Hsien-Hsin Chen, Ji-Hong Hong
Introductions: Prostate-selective α antagonists are recommended for relief of lower urinary tract symptoms in prostate cancer patients despite uncertainty of fracture risk as an addition to androgen deprivation therapy (ADT). The purpose of this study is to estimate fracture risk associated with these medications in prostate cancer patients who did and did not receive ADT. Methods: The Taiwan National Health Insurance database was used to identify prostate cancer patients...
January 12, 2018: Oncotarget
https://www.readbyqxmd.com/read/29433801/risk-factors-of-fixation-failure-in-basicervical-femoral-neck-fracture-which-device-is-optimal-for-fixation
#11
Young-Kyun Lee, Byung-Ho Yoon, Ji Sup Hwang, Yong-Han Cha, Ki-Choul Kim, Kyung-Hoi Koo
BACKGROUND: Basicervical femur neck fracture (FNF) is a rare type of fracture, and is associated with increased risk of fixation failure due to its inherent instability. The purpose of this study was (1) to investigate the incidence of fixation failure and (2) to determine risk factors for fixation failure in basicervical FNF after internal fixation. METHODS: To identify basicervical FNF with a minimum of 12 months follow-up, we retrospectively reviewed records of 3217 patients who underwent hip fracture surgery from May 2003 to March 2016...
February 9, 2018: Injury
https://www.readbyqxmd.com/read/29432317/the-outcomes-of-early-surgical-intervention-in-geriatric-proximal-femur-fractures-among-patients-receiving-direct-oral-anticoagulation
#12
Nathan A Franklin, Ashley Ali, Richard K Hurley, Hassan R Mir, Michael J Beltran
OBJECTIVE: Evaluate the pre-hospital use of Direct Oral Anticoagulant (DOAC) agents on the outcomes of early surgical fixation of a geriatric hip fracture. DESIGN: Case-Control. SETTING: Two academic level 1 trauma centers. INTERVENTION: Early (<48h) surgical fixation of a geriatric proximal femur fracture. PATIENTS: 19 patients receiving Pradaxa (Dabigatran), Eliquis (Apixaban), or Xarelto (Rivaroxaban) who underwent surgery between 2010 and 2015 and 74 control patients...
February 9, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29430494/elastic-stable-intramedullary-nailing-of-femoral-shaft-fracture-experience-in-48-children
#13
Rajesh Govindasamy, Ramkumar Gnanasundaram, Saravanan Kasirajan, Syed Ibrahim, Jimmy Joseph Melepuram
Background: Femoral shaft fractures are an incapacitating pediatric injury accounting for 1.6% of all pediatric bony injuries. Management of these fractures is largely directed by age, fracture pattern, associated injuries, built of the child and socioeconomic status of the family. We retrospectively evaluated the use of elastic stable intramedullary nail (ESIN) in surgical management of femoral shaft fractures in children and its complications. Methods: Fifty two children were treated with titanium elastic nails (TEN) from June 2009 to June 2014 at our institution...
January 2018: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29429892/osteosarcoma-subtypes-magnetic-resonance-and-quantitative-diffusion-weighted-imaging-criteria
#14
Rania Zeitoun, Ahmed M Shokry, Sahar Ahmed Khaleel, Shaimaa M Mogahed
INTRODUCTION: Osteosarcoma (OS) is a primary bone malignancy, characterized by spindle cells producing osteoid. The objective of this study is to describe the magnetic resonance imaging (MRI) features of different OS subtypes, record their attenuation diffusion coefficient (ADC) values and to point to the relation of their pathologic base and their corresponding ADC value. PATIENTS AND METHODS: We performed a retrospective observational lesion-based analysis for 31 pathologically proven osteosarcoma subtypes: osteoblastic (n = 9), fibroblastic (n = 8), chondroblastic (n = 6), para-osteal (n = 3), periosteal (n = 1), telangiectatic (n = 2), small cell (n = 1) and extra-skeletal (n = 1)...
February 8, 2018: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/29429857/risk-factors-for-trochanteric-and-femoral-neck-fracture
#15
A R Díaz, P Z Navas
INTRODUCTION AND OBJECTIVES: The differences between the two main types of fracture of proximal end of the femur, trochanteric and cervical fractures, are still a subject of study, and could be the key to a better understanding of its pathophysiology and prevention. The aim of this study is to determine whether epidemiological differences in the distribution of risk factors associated with hip fracture exist between these two entities. PATIENTS AND METHOD: A descriptive cross-sectional study of 428 patients over the age of 65 admitted for trochanteric or cervical fractures in 2015, in which gender, age, previous diagnosis, external causes associated with fracture and place of the event were recorded...
February 8, 2018: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/29429478/-femur-shaft-fractures-in-infants-should-be-considered-despite-no-known-trauma
#16
Ahmed Abdul-Hussein Abood, Jens Svendsson, Søren Harvig
Femur shaft fractures in infants are rare and associated with abuse or fall from heights. The fracture is often easy to recognize on X-ray, however, the determination of the indication can be difficult. It is important to pay attention to pain signals from the extremity and the objective findings, such as a swollen and tight thigh. Early recognition of the fracture is of importance to the prognosis and to detection of possible violence resulting in battered child syndrome. Exploration for injuries of the extremities is of utmost necessity in these cases, despite the absence of trauma in the anamnesis...
February 5, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29429066/outcomes-following-surgical-management-of-femoral-neck-fractures-in-elderly-dialysis-dependent-patients
#17
Varun Puvanesarajah, Raj Amin, Rabia Qureshi, Babar Shafiq, Ben Stein, Hamid Hassanzadeh, Seth Yarboro
INTRODUCTION: Proximal femur fractures are one of the most common fractures observed in dialysis-dependent patients. Given the large comorbidity burden present in this patient population, more information is needed regarding post-operative outcomes. The goal of this study was to assess morbidity and mortality following operative fixation of femoral neck fractures in the dialysis-dependent elderly. METHODS: The full set of medicare data from 2005 to 2014 was retrospectively analyzed...
February 10, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29428933/a-comparison-of-the-effects-of-grayanotoxin-containing-honey-mad-honey-normal-honey-and-propolis-on-fracture-healing
#18
Aynur Sahin, Suha Turkmen, Nizamettin Guzel, Ahmet Menteşe, Suleyman Turedi, Suleyman Caner Karahan, Esin Yulug, Selim Demir, Osman Aynaci, Orhan Deger, Abdulkadir Gunduz
OBJECTIVES: Delayed healing and non-union of fractures have a significant effect upon patient morbidity. Studies have therefore largely concentrated on accelerating fracture healing. This study was intended to compare the effect of "mad honey" and propolis on fracture healing using radiological and histopathological analysis. SUBJECTS AND METHODS: Femur fracture was surgically performed on 48 rats, followed by fixation. Animals were then divided into eight groups; two control groups (15- and 30-day) and six treatment groups (15- and 30-day normal honey, 15- and 30-day "mad honey" and 15- and 30-day propolis)...
February 11, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29428321/cement-augmentation-in-the-proximal-femur-to-prevent-stem-subsidence-in-revision-hip-arthroplasty-with-paprosky-type-ii-iiia-defects
#19
Shang-Wen Tsai, Cheng-Fong Chen, Po-Kuei Wu, Chao-Ming Chen, Wei-Ming Chen
BACKGROUND: Subsidence remains a common complication after revision hip arthroplasty which may lead to prolonged weight-bearing restrictions, leg-length discrepancies or considerable loss of function. We evaluated the effectiveness of cement augmentation in the proximal femoral metaphysis during a revision of femoral components to prevent post-operative stem subsidence. METHODS: Forty patients were enrolled. Follow-up averaged 67.7 months (range: 24-149). Twenty-seven patients had a Paprosky type II defect and 13 had a type IIIa defect...
February 7, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29424771/t-cell-receptor-activator-of-nuclear-factor-%C3%AE%C2%BAb-ligand-osteoprotegerin-imbalance-is-associated-with-hiv-induced-bone-loss-in-patients-with-higher-cd4-t-cell-counts
#20
Kehmia Titanji, Aswani Vunnava, Antonina Foster, Anandi N Sheth, Jeffrey L Lennox, Andrea Knezevic, Neeta Shenvi, Kirk A Easley, Ighovwerha Ofotokun, M Neale Weitzmann
OBJECTIVE: Higher incidence of osteopenia and osteoporosis underlie increased rates of fragility fracture in HIV infection. B cells are a major source of osteoprotegerin (OPG), an inhibitor of the key osteoclastogenic cytokine receptor activator of nuclear factor-κB ligand (RANKL). We previously showed that higher B-cell RANKL/OPG ratio contributes to HIV-induced bone loss. T-cell OPG production in humans, however, remains undefined and the contribution of T-cell OPG and RANKL to HIV-induced bone loss has not been explored...
February 8, 2018: AIDS
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