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https://www.readbyqxmd.com/read/29342997/-x-linked-inhibitor-of-apoptosis-deficiency-manifested-as-crohn-s-disease-a-case-report-and-literature-review
#1
L J Xu, Y Y Luo, J D Yu, J G Lou, Y H Fang, J Chen
Objective: To analyze the clinical characteristics of X-linked inhibitor of apoptosis (XIAP) deficient patients with clinical manifestation of Crohn's disease. Methods: Clinical manifestations, laboratory investigations, genetic testing and therapeutic interventions of one case of XIAP deficiency who was admitted to Department of Gastroenterology in Children's Hospital, Zhejiang University School of Medicine in May 2016 were summarized. PubMed and Chinese database for articles published from January 2016 to June 2017 were searched using the key words of'Crohn's disease'and'XIAP', and the relevant literature was reviewed...
January 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29323425/evaluating-mid-upper-arm-circumference-z-score-as-a-determinant-of-nutrition-status
#2
Karen Stephens, April Escobar, Erika Nicole Jennison, Lindsey Vaughn, Rhonda Sullivan, Susan Abdel-Rahman
BACKGROUND: Mid-upper arm circumference (MUAC) z-score, has recently been listed as an independent indicator for pediatric malnutrition. This investigation examined the relationship between MUAC z-score and the z-scores for conventional indicators (ie, weight-for-length and body mass index) to expand the available evidence for nutrition classification z-score threshold ranges in U.S. practice settings. METHODS: This was a single-center study of children through 18 years of age seen between October 2015 and September 2016...
January 11, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29285442/prevalence-and-etiological-profile-of-short-stature-among-school-children-in-a-south-indian-population
#3
Kumaravel Velayutham, S Sivan Arul Selvan, R V Jeyabalaji, S Balaji
Background and Objectives: Short stature (SS) is a common pediatric problem and it might be the first sign of underlying illness. Studies documenting the burden and etiological profile of SS are scarce from India and are mostly limited to data obtained from referral centers. Due to the lack of large-scale, community-based studies utilizing a standard protocol, the present study aimed to assess the prevalence and etiological profile of SS in school children of a South Indian district. Materials and Methods: In this cross-sectional study, children aged 4-16 years from 23 schools in Madurai district, Tamil Nadu, underwent anthropometric measurements and height was plotted in Khadilkar et al...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29248034/health-outcomes-for-children-in-haiti-since-the-2010-earthquake-a-systematic-review
#4
Annie Dube, Madeline Moffatt, Colleen Davison, Susan Bartels
BACKGROUND: Haiti remains the poorest country in the Americas and one of the poorest in the world. Children in Haiti face many health concerns, some of which were exacerbated by the 2010 earthquake. This systematic review summarizes published research conducted since the 2010 earthquake, focusing on health outcomes for children in Haiti, including physical, psychological, and socioeconomic well-being. METHODS: A literature search was conducted identifying articles published from January 2010 through May 2016 related to pediatric health outcomes in Haiti...
December 18, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29243190/faltering-growth-in-the-critically-ill-child-prevalence-risk-factors-and-impaired-outcome
#5
Frédéric V Valla, Julien Berthiller, Bénédicte Gaillard-Le-Roux, Carole Ford-Chessel, Tiphanie Ginhoux, Shancy Rooze, Fleur Cour-Andlauer, Rosan Meyer, Etienne Javouhey
Low body mass index (BMI) z score is commonly used to define undernutrition, but faltering growth allows for a complementary dynamic assessment of nutritional status. We studied the prevalence of undernutrition and faltering growth at admission in the pediatric intensive care (PICU) setting and their impacts on outcome. All (685) consecutive children (aged 0 to 18 years old) admitted in a single-center PICU over a 1-year period were prospectively enrolled. Nutritional status assessment was based on anthropometric measurements performed at admission and collected from medical files...
December 14, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29227466/morbidity-and-mortality-of-a-cohort-of-peruvian-hiv-infected-children-2003-2012
#6
Amira N Baker, Angela M Bayer, Rolando M Viani, Lenka Kolevic, Myung-Shin Sim, Jaime G Deville
BACKGROUND: Data on pediatric HIV in Peru is limited. The National Institute of Child Health (Instituto Nacional de Salud del Niño: INSN) cares for the most HIV-infected children under age 18 in the country. We describe the outcomes of children seen at INSN's HIV clinic over the 10 years when antiretroviral therapy (ART) and prevention of mother-to-child transmission (PMTCT) interventions became available in 2004. METHODS: We conducted a retrospective review of INSN HIV clinic patients between 2003-2012...
December 8, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29227461/population-pharmacokinetics-of-lopinavir-in-severely-malnourished-hiv-infected-children-and-the-effect-on-treatment-outcomes
#7
Moherndran Archary, Helen Mcllleron, Raziya Bobat, Phillip La Russa, Thobekile Sibaya, Lubbe Wiesner, Stefanie Hennig
BACKGROUND: In developing countries, malnutrition remains a common clinical syndrome at antiretroviral treatment (ART) initiation. Physiological changes due to malnutrition and during nutritional recovery could affect the pharmacokinetics of antiretroviral drugs. METHODS: HIV-infected children admitted with severe acute malnutrition were randomised to early or delayed initiation of lopinavir/ritonavir, abacavir and lamivudine using WHO weight-band dosage charts...
December 8, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29222881/development-and-validation-of-a-pediatric-nutritional-screening-score-pnss-for-hospitalized-children
#8
Lina Lu, Xiaomeng Mao, Jinye Sheng, Jianhu Huang, Ying Wang, Qingya Tang, Wei Cai
BACKGROUND AND OBJECTIVES: There is no evidence on the most effective nutritional screening tool for hospitalized children. The objective of this study was to develop and validate a pediatric nutritional screening tool to assess undernutrition risk upon hospital admission. METHODS AND STUDY DESIGN: The study had a two-phase prospective observational design. A novel pediatric nutritional screening score (PNSS) was developed and sensitivity, specificity, and reliability were evaluated by comparing with a complete dietetic assessment...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29177377/-epidermolysis-bullosa-in-peru-clinical-and-epidemiological-study-of-patients-treated-in-a-national-reference-pediatric-hospital-1993-2015
#9
Rosario Torres-Iberico, Patricia Palomo-Luck, Gilmer Torres-Ramos, Roxana Lipa-Chancolla
OBJECTIVES: To describe the clinical and epidemiological characteristics of patients diagnosed with epidermolysis bullosa (EB) at the Instituto Nacional de Salud (INSN) in Lima, Peru; a National Reference Center for this disease. MATERIALS AND METHODS: Observational, descriptive and transversal study. We reviewed the clinical histories and laboratory tests of patients diagnosed with EB treated in INSN from 1993 to 2015. RESULTS: 93 patients were registered...
April 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/29168361/hypophosphatemia-associated-risk-factors-in-pediatric-intensive-care-patients
#10
Emine Sibel Şan, Seher Erdoğan, Mehmet Boşnak, Murat Şan
Şan ES, Erdoğan S, Boşnak M, Şan M. Hypophosphatemia associated risk factors in pediatric intensive care patients. Turk J Pediatr 2017; 59: 35-41. The aim of this work is to determine the prevalence and risk factors of hypophosphatemia in pediatric patients admitted to intensive care unit. The study was performed prospectively in patients admitted to the Pediatric Intensive Care Unit between June 2014 and December 2014. Fifty-seven patients were included in the study. The mean age of the study population was 24 months (2-192 months); 25 patients (43...
2017: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/29166191/the-pediatric-yorkhill-malnutrition-score-is-a-reliable-malnutrition-screening-tool
#11
Nur Eni Lestari, Nani Nurhaeni, Dessie Wanda
Children often experience malnutrition while they are hospitalized. Therefore, the prevention of malnutrition and nutritional management need to be done properly using malnutrition screening tools. This study aimed to determine the sensitivity and specificity of the Pediatric Yorkhill Malnutrition Score (PYMS) and the Screening Tool for the Risk of Impaired Nutritional Status and Growth (STRONGkids) when compared to the Subjective Global Nutritional Assessment for Children (SGNA). This study involved 81 pediatric patients with ages ranging from 1 to 16 years old...
2017: Comprehensive Child and Adolescent Nursing
https://www.readbyqxmd.com/read/29165513/-a-five-year-experience-with-zoonotic-salmonella-at-a-pediatric-reference-centre
#12
Patricia Barrios, Federica Badía, Valentina Misa, M Inés Mota, Arací Martínez, Hebert Mariño, Gabriela Algorta, Javier Prego, M Catalina Pírez
BACKGROUND: Salmonella can cause asymptomatic infections, diarrhea, bacteremia and focal infections such as meningitis and osteomyelitis. AIM: To describe clinical and microbiological aspects of infections by Salmonella spp. in children in a pediatric referral hospital: Centro Hospitalario Pereira Rossell, in Montevideo, Uruguay. MATERIALS AND METHODS: Descriptive and retrospective study of 46 patients, from which Salmonella spp was isolated between January 1, 2005 and December 31, 2010...
August 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29130701/patient-generated-subjective-global-assessment-of-nutritional-status-in-pediatric-patients-with-recent-cancer-diagnosis
#13
Mayra Jezabel Vázquez de la Torre, Katja Stein, Edgar Manuel Vásquez Garibay, Miguel Roberto Kumazawa Ichikawa, Rogelio Troyo Sanromán, Alicia Guadalupe Salcedo Flores, Fernando Antonio Sánchez Zubieta
BACKGROUND: The subjective global assessment (SGA) is a simple, sensitive tool used to identify nutritional risk. It is widely used in the adult population, but there is little evidence on its effectiveness in children with cancer. OBJECTIVE: This cross-sectional study was undertaken to demonstrate significant correlation between a simplified version of the Patient-Generated SGA (PG-SGA) and anthropometric assessment to identify nutritional status in children recently diagnosed with cancer...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29119032/cytomegalovirus-associated-duodenal-ulcer-and-duodenitis-in-a-malnourished-pediatric-patient
#14
Rachel Bernard, Ghanim Aljomah, Emily Klepper, Elizabeth McDonough
Cytomegalovirus (CMV) duodenitis is a rare occurrence, especially in pediatric patients. A thirteen-month-old female presented to the Emergency Department for a febrile seizure. She was incidentally admitted for severe malnutrition with an initial workup remarkable for only a slight elevation in her ALT at 48. The patient was found to have an oral aversion requiring nasogastric tube feeds for adequate caloric intake. She continued to fail to gain weight and underwent an EGD that demonstrated a duodenal ulcer...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29101428/composition-of-urinary-calculi-in-infants-a-report-from-an-endemic-country
#15
Mirza Naqi Zafar, Salma Ayub, Hafsa Tanwri, Syed Ali Anwar Naqvi, Syed Adibul Hasan Rizvi
Pediatric urolithiasis remains endemic in low-resource countries where infants constitute 17-40% of all children with urolithiasis. This study reports socio-economic factors, medical history and chemical composition of urinary stones in 976 infants of up to 2 years of age. Between 1992 and 2016, 976 infants presented to our institute with 1038 stones. Chemical composition of stones was analyzed by Fourier transformation infrared spectroscopy (FTIR). The mean age of infants was 19.5 ± 5.74 months with a M:F ratio of 5...
November 3, 2017: Urolithiasis
https://www.readbyqxmd.com/read/29080380/nutritional-risk-factors-predict-severe-acute-graft-versus-host-disease-and-early-mortality-in-pediatric-allogeneic-hematopoietic-stem-cell-transplantation
#16
Eva H Kerby, Yimei Li, Kelly D Getz, Elizabeth C Smith, Laura T Smith, Nancy J Bunin, Alix E Seif
BACKGROUND: Malnutrition is a pro-inflammatory state, yet data on nutritional risk factors and development of acute graft-versus-host disease (aGVHD) are extremely limited. PROCEDURE: We conducted a retrospective cohort analysis of pediatric patients up to age 21 years who underwent allogeneic hematopoietic stem cell transplantation (HSCT) at the Children's Hospital of Philadelphia from January 2011 to September 2014 to determine whether malnutrition was associated with development of aGVHD and early mortality...
October 28, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29072244/oral-and-dental-health-in-children-with-chronic-liver-disease-in-the-turkey-northeast
#17
O Baygin, M Cakır, N Ucuncu
BACKGROUND: It is important to be aware of oral and dental problems in the early period in children with chronic liver disease (CLD) to prevent late complications. Therefore, we aimed to analyze the oral and dental health status in children with CLD. METHODS: The three groups of children (3-18 years old); Group 1 (disease group, n = 31) patients with CLD, Group 2 (disease control group, n = 17) patients with chronic renal failure, and Group 3 healthy children (control group, n = 35)...
September 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29062911/using-data-from-a-multi-hospital-clinical-network-to-explore-prevalence-of-pediatric-rickets-in-kenya
#18
Stella W Karuri, Maureen K Murithi, Grace Irimu, Mike English
Background: Nutritional rickets is a public health concern in developing countries despite tropical climates and a re-emerging issue in developed countries. In this study, we reviewed pediatric admission data from the Clinical Information Network (CIN) to help determine hospital and region based prevalence of rickets in three regions of Kenya (Central Kenya, Western Kenya and Nairobi County). We also examine the association of rickets with other diagnosis, such as malnutrition and pneumonia, and study the effect of rickets on regional hospital stays...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/28992388/impact-of-nutrition-interventions-on-pediatric-mortality-and-nutrition-outcomes-in-humanitarian-emergencies
#19
REVIEW
Kamna S Balhara, David M Silvestri, W Tyler Winders, Anand Selvam, Sean M Kivlehan, Torben K Becker, Adam C Levine
OBJECTIVES: Malnutrition contributes to pediatric morbidity and mortality in disasters and complex emergencies, but summary data describing specific nutritional interventions in these settings are lacking. This systematic review aims to characterize such interventions and their effects on pediatric mortality, anthropometric measures, and serum markers of nutrition. METHODS: A systematic search of OVID Medline, Cochrane Library, and relevant grey literature was conducted...
October 9, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28976806/magnetic-compression-anastomosis-magnamosis-for-functional-undiversion-of-ileostomy-in-pediatric-patients
#20
Luzia Toselli, Marcelo Martinez-Ferro, Guillermo Cervio, Dillon Kwiat, Jill Imamura-Ching, Claire E Graves, Brandon Gaston, Michael Harrison
INTRODUCTION: Magnamosis forms a compression anastomosis using self-aligning magnetic Harrison rings. The device has been approved by the Food and Drug Administration for first-in-human testing and has been applied in adults for intestinal anastomosis during urologic reconstructions. We now report the first cases of magnamosis to functionally undivert the fecal stream from a previously created loop ileostomy in pediatric patients. MATERIALS AND METHODS: Case 1: A 4-year-old male underwent a diverting loop ileostomy for malignant bowel obstruction...
December 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
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