keyword
MENU ▼
Read by QxMD icon Read
search

salvage prostate

keyword
https://www.readbyqxmd.com/read/27904940/-no-evidence-for-improved-outcome-with-salvage-radiotherapy-for-asymptomatic-biochemical-prostate-cancer-recurrence-after-prostatectomy-by-additive-androgen-suppression
#1
Helena Garcia Schüler, Matthias Guckenberger
No abstract text is available yet for this article.
November 30, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27893926/estimation-of-the-optimal-regime-in-treatment-of-prostate-cancer-recurrence-from-observational-data-using-flexible-weighting-models
#2
Jincheng Shen, Lu Wang, Jeremy M G Taylor
Prostate cancer patients are closely followed after the initial therapy and salvage treatment may be prescribed to prevent or delay cancer recurrence. The salvage treatment decision is usually made dynamically based on the patient's evolving history of disease status and other time-dependent clinical covariates. A multi-center prostate cancer observational study has provided us data on longitudinal prostate specific antigen (PSA) measurements, time-varying salvage treatment, and cancer recurrence time. These data enable us to estimate the best dynamic regime of salvage treatment, while accounting for the complicated confounding of time-varying covariates present in the data...
November 28, 2016: Biometrics
https://www.readbyqxmd.com/read/27878044/a-comparative-study-of-radical-prostatectomy-and-permanent-seed-brachytherapy-for-low-and-intermediate-risk-prostate-cancer
#3
Daniel Taussky, Véronique Ouellet, Guila Delouya, Fred Saad
INTRODUCTION: We sought to compare the outcomes between radical prostatectomy (RP) and permanent seed prostate brachytherapy (PB) in patients with low- and low-intermediate-risk prostate cancer from a single tertiary care centre. METHODS: Patients were selected from our institute's internal database based on preoperative selection criteria from the National Comprehensive Cancer Network (NCCN) guidelines (2015) for low- and intermediate-risk patients. No patient had received any neo-adjuvant androgen-deprivation therapy...
August 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27873241/predictive-factors-of-18-f-choline-pet-ct-positivity-in-patients-with-prostate-cancer-recurrence-after-radiation-therapy-is-the-impact-of-psa-nadir-underestimated
#4
Alison C Johnson, Audrey Emmanuelle Dugué, Marlon Silva, Laura Moise, Xavier Tillou, Florence Joly, Nicolas Aide
BACKGROUND: The objective of this study is to explore the impact of PSA nadirs on detection rates of prostate cancer (PCa) recurrence with (18)F-choline (CH) PET/CT after external beam radiation therapy (EBRT). METHODS: In this retrospective study, data were collected from 54 patients with suspicion of PCa biochemical recurrence after EBRT (28 patients treated initially with EBRT and 26 as salvage therapy in the absence of PSA decrease after initial treatment), who underwent (18)F-CH PET/CT between 2010 and 2015...
December 2016: EJNMMI Research
https://www.readbyqxmd.com/read/27867812/comparisons-of-oncological-and-functional-outcomes-among-radical-retropubic-prostatectomy-high-dose-rate-brachytherapy-cryoablation-and-high-intensity-focused-ultrasound-for-localized-prostate-cancer
#5
Po Hui Chiang, Yi Yang Liu
PURPOSE: To conduct a retrospective, single institutional and comparative study for radical retropubic prostatectomy (RRP), high dose rate brachytherapy (HDRBT), cryoablation and high-intensity focused ultrasound (HIFU) in localized prostate cancer with respect to oncological and functional outcomes. METHODS: We reviewed 97, 161, 114 and 120 patients of RRP, HDRBT, cryoablation and HIFU respectively for localized prostate cancer from May 2008 to December 2013. PSA biochemical recurrence, salvage treatment-free rate, metastasis-free rate, and biochemical recurrence-free survival were analyzed for oncological outcomes...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27863963/the-dose-response-of-salvage-radiotherapy-following-radical-prostatectomy-a-systematic-review-and-meta-analysis
#6
Christopher R King
PURPOSE/OBJECTIVES: To date neither the optimal radiotherapy dose nor the existence of a dose-response has been established for salvage RT (SRT). MATERIALS/METHODS: A systematic review from 1996 to 2015 and meta-analysis was performed to identify the pathologic, clinical and treatment factors associated with relapse-free survival (RFS) after SRT (uniformly defined as a PSA>0.2ng/mL or rising above post-SRT nadir). A sigmoidal dose-response curve was objectively fitted and a non-parametric statistical test used to determine significance...
November 15, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27862863/value-of-111-in-psma-radioguided-surgery-for-salvage-lymphadenectomy-in-recurrent-prostate-cancer-correlation-with-histopathology-and-clinical-follow-up
#7
Isabel Rauscher, Charlotte Düwel, Martina Wirtz, Margret Schottelius, Hans-Jürgen Wester, Kristina Schwamborn, Bernhard Haller, Markus Schwaiger, Jürgen E Gschwend, Matthias Eiber, Tobias Maurer
OBJECTIVES: To evaluate the use of (111) In-labeled PSMA-I&T based radioguided surgery ((111) In-PSMA-RGS) for salvage surgery in recurrent prostate cancer (PC) using comparison of intraoperative γ-probe measurements to histopathological results of dissected specimens. Furthermore, the success of (111) In-PSMA-RGS was determined by postoperative prostate-specific antigen (PSA) responses, PC-specific treatment-free survival as well as postoperative complication rates. PATIENTS AND METHODS: In this study, 31 consecutive patients with localized recurrent PC undergoing salvage surgery with PSMA-targeted RGS using an (111) In-labeled PSMA ligand were retrospectively included from April 2014 to July 2015...
November 10, 2016: BJU International
https://www.readbyqxmd.com/read/27842722/choline-positron-emission-tomography-computed-tomography-for-selection-of-patients-for-salvage-strategies-after-primary-local-treatment-of-prostate-cancer-and-rising-prostate-specific-antigen-ready-for-prime-time
#8
EDITORIAL
https://www.readbyqxmd.com/read/27824042/the-role-of-salvage-extended-lymph-node-dissection-in-patients-with-rising-psa-and-pet-ct-scan-detected-nodal-recurrence-of-prostate-cancer
#9
D Porres, D Pfister, A Thissen, T H Kuru, V Zugor, R Buettner, R Knuechel, F A Verburg, A Heidenreich
BACKGROUND: Non-prostatic bed recurrence of prostate cancer (PCa) is usually treated with androgen deprivation therapy (ADT). We analyzed the impact of salvage extended lymph node dissection (sLND) on cancer control in patients with rising PSA and lymph node (LN) metastases. METHODS: Between 2009 and 2016 we performed sLND in 87 patients with biochemical recurrence (BCR) and positive LNs on (18)FEC and (68)Ga-PSMA positron emission tomography/X-ray computer tomography (PET/CT) after primary treatment (PT) of PCa...
November 8, 2016: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/27815083/salvage-surgery-for-nodal-recurrence-of-prostate-cancer-might-the-robotic-approach-render-an-experimental-procedure-more-acceptable
#10
EDITORIAL
Riccardo Schiavina, Lorenzo Bianchi, Marco Borghesi, Giuseppe Martorana, Eugenio Brunocilla
No abstract text is available yet for this article.
November 1, 2016: European Urology
https://www.readbyqxmd.com/read/27810195/transrectal-implantation-and-stability-of-gold-markers-in-prostate-bed-for-salvage-radiotherapy-of-macroscopic-recurrences
#11
Shakir I Shakir, Corina Udrescu, Ciprian Enachescu, Olivier Rouviere, Simona Arion, Ionela Caraivan, Olivier Chapet
BACKGROUND AND PURPOSE: The objective of the study was to verify the stability of gold markers in the prostatic bed (PB) during salvage radiotherapy. MATERIAL AND METHODS: Seven patients, diagnosed with a macroscopic nodule visible on MRI, underwent targeted MRI-guided biopsies. Three gold markers were implanted into the PB close to the relapsing nodule for CT/MRI fusion. A dose of 60Gy was delivered using IMRT to the PB followed by a dose escalation up to 72Gy to the macroscopic nodule...
November 2016: Physica Medica: PM
https://www.readbyqxmd.com/read/27800051/assessing-guideline-impact-on-referral-patterns-of-post-prostatectomy-patients-to-radiation-oncologists
#12
Amandeep Taggar, Majed Alghamdi, Derek Tilly, Xanthoula Kostaras, Marc Kerba, Siraj Husain, Geoff Gotto, Michael Sia
INTRODUCTION: Adjuvant radiotherapy (aRT) can improve biochemical progression-free survival in patients with high-risk features (HRF) after radical prostatectomy (RP). Guidelines from Alberta and the Genitourinary Radiation Oncologists of Canada (GUROC) recommend that patients with HRF be referred to radiation oncologists (RO) based on the findings from three randomized, controlled trials (RCT). Our study examines the impact of these recommendations both pre- (2005) and post- (2012) publication of RCT and GUROC guideline establishment...
September 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27799004/comparing-high-intensity-focal-ultrasound-hemiablation-to-robotic-radical-prostatectomy-in-the-management-of-unilateral-prostate-cancer-a-matched-pair-analysis
#13
Simone Albisinni, Fouad Aoun, Simon Bellucci, Ibrahim Biaou, Ksenija Limani, Eric Hawaux, Alexandre Peltier, Roland van Velthoven
INTRODUCTION: Although still experimental, focal treatment is being increasingly implemented in the management of prostate cancer (PCa). Aim of the current study was to compare functional and oncologic outcomes of high-intensity focal ultrasound (HIFU) hemiablation of the prostate to robot-assisted laparoscopic prostatectomy (RALP) in the management of unilateral PCa. MATERIALS: Fifty-five men with unilateral, clinically localized PCa underwent HIFU hemiablation of the affected prostatic lobe between 2007 and 2015...
November 30, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27796820/whole-body-diffusion-weighted-magnetic-resonance-imaging-wb-dw-mri-vs-choline-positron-emission-tomography-computed-tomography-choline-pet-ct-for-selecting-treatments-in-recurrent-prostate-cancer
#14
A J Conde-Moreno, G Herrando-Parreño, R Muelas-Soria, J Ferrer-Rebolleda, R Broseta-Torres, M P Cozar-Santiago, F García-Piñón, C Ferrer-Albiach
OBJECTIVE: To determine the effectiveness of whole-body diffusion-weighted magnetic resonance imaging (WB-DW-MRI) in detecting metastases by comparing the results with those from choline-positron emission tomography-computed tomography (choline-PET/CT) in patients with biochemical relapse after primary treatment, and no metastases in bone scintigraphy, CT and/or pelvic MRI, or metastatic/oligometastatic prostate cancer (PCa). Patients with this disease profile who could benefit from treatment with stereotactic body radiation therapy (SBRT) were selected and their responses to these techniques were rated...
October 31, 2016: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/27791459/tumor-infiltrating-t-lymphocytes-expressing-foxp3-ccr7-or-pd-1-predict-the-outcome-of-prostate-cancer-patients-subjected-to-salvage-radiotherapy-after-biochemical-relapse
#15
Valerio Nardone, Cirino Botta, Michele Caraglia, Elodia Claudia Martino, Maria Raffaella Ambrosio, Tommaso Carfagno, Paolo Tini, Leonardo Semeraro, Gabriella Misso, Anna Grimaldi, Mariarosaria Boccellino, Gaetano Facchini, Massimiliano Berretta, Gianluca Vischi, Bruno Jim Rocca, Aurora Barone, Pierfrancesco Tassone, Pierosandro Tagliaferri, Maria Teresa Del Vecchio, Luigi Pirtoli, Pierpaolo Correale
Tumor immunologic microenvironment is strongly involved in tumor progression and the presence of tumor infiltrating lymphocytes (TIL) with different phenotypes has been demonstrated to be of prognostic relevance in different malignancies. We investigated whether TIL infiltration of tumor tissues could also predict the outcome of prostate cancer patients. To this end, we carried out a retrospective analysis correlating the outcome of locally advanced prostate cancer patients undergone salvage radiotherapy upon relapse after radical surgery with the infiltration by different TIL populations...
October 28, 2016: Cancer Biology & Therapy
https://www.readbyqxmd.com/read/27790303/salvage-radiation-therapy-11-years-after-a-radical-prostatectomy
#16
Valérie Hogues, Carole Lambert, Michael McCormack
We present a patient with a high prostate-specific antigen (PSA) value, who was successfully treated with salvage radiation therapy (RT) 11 years after a radical prostatectomy (RP).
May 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27785766/impact-of-68-ga-psma-pet-ct-on-salvage-radiotherapy-planning-in-patients-with-prostate-cancer-and-persisting-psa-values-or-biochemical-relapse-after-prostatectomy
#17
Christina Bluemel, Fraenze Linke, Ken Herrmann, Iva Simunovic, Matthias Eiber, Christian Kestler, Andreas K Buck, Andreas Schirbel, Thorsten A Bley, Hans-Juergen Wester, Daniel Vergho, Axel Becker
BACKGROUND: Salvage radiotherapy (SRT) is clinically established in prostate cancer (PC) patients with PSA persistence or biochemical relapse (BCR) after prior radical surgery. PET/CT imaging prior to SRT may be performed to localize disease recurrence. The recently introduced (68)Ga-PSMA outperforms other PET tracers for detection of recurrence and is therefore expected also to impact radiation planning. Forty-five patients with PSA persistence (16 pts) or BCR (29 pts) after prior prostatectomy, scheduled to undergo SRT of the prostate bed, underwent (68)Ga-PSMA PET/CT...
December 2016: EJNMMI Research
https://www.readbyqxmd.com/read/27761695/cryosurgery-an-alternative-treatment-option-for-organ-confined-prostate-cancer-current-beliefs-and-practice-patterns-of-urologists
#18
Michael Kongnyuy, Daniel M Halpern, Kaitlin E Kosinski, Aaron E Katz
PURPOSE: We aim to evaluate the current beliefs and practice patterns of urologists in regard to use of cryosurgery for management of PCa. METHODS: An anonymous 13-point survey was designed and sent out to members of the Society of Urologic Oncology (SUO), Endourological Society (ES) and American College of Cryosurgery (ACC). Descriptive statistics and univariate analyses were used to determine variables associated with the use of cryosurgery. RESULTS: Of the 206 responses received [81 (39...
October 19, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27761612/dynamic-contrast-enhanced-mri-for-automatic-detection-of-foci-%C3%AF-of-residual-or-recurrent-disease-after-prostatectomy
#19
N Andres Parra, Amber Orman, Kyle Padgett, Victor Casillas, Sanoj Punnen, Matthew Abramowitz, Alan Pollack, Radka Stoyanova
PURPOSE: This study aimed to develop an automated procedure for identifying suspicious foci of residual/recurrent disease in the prostate bed using dynamic contrast-enhanced-MRI (DCE-MRI) in prostate cancer patients after prostatectomy. MATERIALS AND METHODS: Data of 22 patients presenting for salvage radiotherapy (RT) with an identified gross tumor volume (GTV) in the prostate bed were analyzed retrospectively. An unsupervised pattern recognition method was used to analyze DCE-MRI curves from the prostate bed...
October 19, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27756494/hip-related-toxicity-after-prostate-radiotherapy-treatment-related-or-coincidental
#20
Michael J Zelefsky, Marisa A Kollmeier, Elan Gorshein, Xin Pei, Marina Torres, Sean McBride, Laura Happersett, Gil'ad N Cohen, Yoshiya Yamada
BACKGROUND AND PURPOSE: To evaluate the incidence and predictors of hip toxicity postradiotherapy for localized prostate cancer. METHODS AND MATERIALS: 4067 prostate cancer patients were treated with external beam radiotherapy (EBRT; n=2569; 63%) or brachytherapy with or without supplemental EBRT (n=1508; 27%). 43% (n=1738) were treated with neo-adjuvant and concurrent ADT and 57% (n=2329) with radiotherapy alone. Hip toxicity was defined as moderate or severe pain upon ambulation with or without the need for hip-revision surgery...
October 15, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
keyword
keyword
98726
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"