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Fine needle aspiration cytology

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https://www.readbyqxmd.com/read/29229364/pathology-and-management-of-masses-in-the-accessory-parotid-gland-region-24-year-experience-at-a-single-institution
#1
Hailong Ma, Shufang Jin, Zhong Du, Lizhen Wang, Zhiyuan Zhang, Yan'an Wang
PURPOSE: Masses in the accessory parotid gland (APG) region are clinically rare and their management can lead to conflicts between the need for tumor resection and facial cosmesis. The aim of this study was to analyze the pathological classifications and management of APG lesions in our hospital. MATERIALS AND METHODS: From January 1993 to March 2017, 130 patients with primary tumors in the APG region who underwent surgical treatment were enrolled. Follow-up surveys after surgery were then carried out...
November 17, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29228842/mammary-analogue-secretory-carcinoma-of-the-thyroid-mimicking-locally-advanced-papillary-thyroid-carcinoma-a-rare-case-report
#2
Haihui Liao, Ashraf Khan, Patricia M Miron, Kristine M Cornejo
Mammary analogue secretory carcinoma (MASC) harboring ETV6 gene rearrangements was first described in the salivary gland with a relatively favorable prognosis and a possible molecular therapeutic target with pan-Trk inhibitors. Recently, primary MASC of the thyroid gland has been reported. We report a case of a 4.0 cm MASC arising from the left thyroid of a 58-year-old female with extrathyroidal extension. Initially, it was diagnosed by fine needle aspiration as suspicious for papillary thyroid carcinoma (PTC) and subsequently called a poorly differentiated carcinoma on resection...
December 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29218317/agreement-between-endoscopic-ultrasound-guided-fine-needle-aspiration-and-endobiliary-brush-cytology-in-suspected-pancreaticobiliary-malignancies
#3
Matthew J Sullivan, Hope Kincaid, Shashin Shah, Hiral N Shah
Background and study aims:  For suspected pancreaticobiliary malignancies, endobiliary brush cytology during endoscopic retrograde cholangiopancreatography (ERCP) remains the diagnostic test of choice despite historically poor and variable sensitivity. This has led to increased use of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) as an initial test. Recently, our institution began using a cytology brush that was designed specifically to collect a more substantial and higher-quality sample...
December 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29218288/giant-anterior-neck-lipoma-with-bleeding-pressure-ulcer-in-an-elderly-man-a-rare-entity
#4
Gaurav Jain, Ila Tyagi, Leela Pant, Namrata Nargotra
Giant lipomas are benign soft tissue tumors found rarely in the neck and are still rarer in the anterior part of the neck. A 70-year-old male patient was presented with a huge swelling measuring 35 cm in maximum dimension, in the front of the neck, reaching up till the umbilicus. The swelling was painless, slow growing and acquired the huge size in approximately 20 years. Ultrasound and CT scan findings were suggestive of a soft tissue lesion. Fine needle aspiration cytology yielded mature adipose tissue fragments...
September 2017: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/29217885/acute-thyroid-swelling-in-renal-transplant-recipient
#5
D P Engineer, S Prakash, A Yadav, J Kumhar, A Biswas, G Kunal, A Goel
Tuberculosis (TB) of thyroid gland is rare entity even in solid organ transplant recipients who have a high risk of TB. Thyroid TB is easily diagnosed by fine needle aspiration cytology. The majority of cases require only antitubercular drugs for treatment, and surgical intervention is required only in few patients. We here describe a case of thyroid TB presenting as an acute abscess in postrenal transplant recipient with a background of acute rejection treated with steroid and antithymocyte globulin.
November 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/29215542/endoscopic-ultrasound-guided-fine-needle-aspiration-cytology-combined-with-automated-quantitative-dna-cytometry-can-improve-the-value-in-the-detection-of-pancreatic-malignancy
#6
Min Zhao, Li Yang, Xin Fu, Qiao Yang, Na Liu, Changcun Guo, Xiaoru Ke, Xin Wang, Xuegang Guo, Kaichun Wu, Daiming Fan, Hongbo Zhang, Xiaoyin Zhang
OBJECTIVES: Quantitative DNA-image cytometry (ICM) is used to diagnose malignancy via detecting changes in DNA content. We aimed to estimate the value of cytology, DNA-ICM, and their combination in diagnosing pancreatic malignancy. METHODS: One hundred twenty-one endoscopic ultrasound-guided fine-needle aspiration samples from 116 patients suspected for pancreatic malignancy were examined by cytology and DNA-ICM. Their results and the final diagnoses (malignancy or not) were collected...
December 5, 2017: Pancreas
https://www.readbyqxmd.com/read/29207802/image-findings-of-solid-pseudopapillary-neoplasms-of-the-pancreas-on-multiphasic-multidetector-ct-scan-a-single-institute-experience-from-southern-india
#7
Santosh Rai, Sonali Prabhu, Sharada Rai, Murali Nirupama, Deepa Sa Adiga, Ashvini Kumar, Shrijeet Chakraborti
Introduction: Solid Pseudopapillary Neoplasms (SPN) are uncommon pancreatic tumours and are slow growing with uncertain malignant potential, showing female preponderance. Postoperative prognosis is good and metastasis is rare. Aim: To summarise the imaging and pathological features of seven cases of SPN in three years period, from January 2013 to January 2016. Materials and Methods: In this retrospective study the imaging features of seven cases on triphasic multidetector Computed Tomogram (CT), a 16-slice scanner, were reviewed along with CT-guided Fine Needle Aspiration Cytology (FNAC) and histopathological examination...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29205961/her2-her3-positive-metastatic-salivary-duct-carcinoma-in-the-pleural-effusion-a-case-report
#8
Kazuya Murata, Akihiko Kawahara, Takeharu Ono, Yorihiko Takase, Hideyuki Abe, Yoshiki Naito, Jun Akiba
Salivary duct carcinoma (SDC) is an aggressive form of salivary gland tumor, and SDC patients tend to be older men, more commonly in advanced stage with a poorer prognosis. Although the cytological characteristics of SDC on fine-needle aspiration cytology have been well-described at the primary site, they have not been explored in metastasis. Here we reported a case of HER2/HER3-positive metastatic SDC in the lung and pleural effusion. The patient was a man in his 50s who had undergone extended total parotidectomy in 2008...
December 4, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29202321/quantitative-analysis-of-breast-cancer-diagnosis-using-a-probabilistic-modelling-approach
#9
Shuo Liu, Jinshu Zeng, Huizhou Gong, Hongqin Yang, Jia Zhai, Yi Cao, Junxiu Liu, Yuling Luo, Yuhua Li, Liam Maguire, Xuemei Ding
BACKGROUND: Breast cancer is the most prevalent cancer in women in most countries of the world. Many computer-aided diagnostic methods have been proposed, but there are few studies on quantitative discovery of probabilistic dependencies among breast cancer data features and identification of the contribution of each feature to breast cancer diagnosis. METHODS: This study aims to fill this void by utilizing a Bayesian network (BN) modelling approach. A K2 learning algorithm and statistical computation methods are used to construct BN structure and assess the obtained BN model...
November 21, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29201471/metastatic-renal-cell-cancer-to-thyroid-diagnosed-by-endoscopic-ultrasound-guided-fine-needle-aspiration-technique
#10
Yousef Abdel-Aziz, Tariq Hammad, Mohamad Nawras, Hayder Abdulwahid, Ali Nawras
Medical literature about the role of endoscopic ultrasound (EUS) in identifying thyroid lesions is limited. We present a case of secondary thyroid cancer from renal cell carcinoma (RCC) metastasis, diagnosed by thyroid EUS-fine needle aspiration (FNA) approach that was done for staging of esophageal adenocarcinoma, in a patient with 11-year history of complete right nephrectomy for RCC. An 81-year-old female patient underwent EUS for the evaluation of a newly discovered distal esophageal cancer. A hypoechoic, round, and well-demarcated mass that measured 26...
2017: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/29200699/metastatic-epithelioid-malignant-peripheral-nerve-sheath-tumor-in-a-known-case-of-neurofibromatosis-1-cytomorphological-appearance-and-critical-analysis-of-immunohistochemistry
#11
Rakesh Kumar Gupta, Ravindra Kumar Saran, Deepak Ghuliani, Lalit Garg, Abhijit Das
Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft tissue tumors commonly arising from nerve roots in the extremities with a predilection in neurofibromatosis (NF) patients. MPNSTs are known to behave aggressively, with worse prognosis in nonresectable cases, and a 5-year survival of about 52% and 15% in resectable and unresectable cases, respectively. Although cytological diagnosis in a known case of NF-1 is possible, however, in the absence of any associated syndrome in a sporadic case, it is very challenging to accurately diagnose this tumor...
July 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29193910/does-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-have-distinctive-features-on-sonography
#12
Tamar C Brandler, Joseph Yee, Fang Zhou, Margaret Cho, Joan Cangiarella, Xiao-Jun Wei, Melissa Yee-Chang, Wei Sun
BACKGROUND: The noninvasive encapsulated follicular variant of papillary carcinoma (nEFVPTC) has recently been reclassified to "noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)," removing this entity from the malignant category. This re-categorization has had major implications for clinical management. NIFTP has overlapping cytohistologic features with papillary thyroid carcinoma (PTC) and with follicular adenomas (FA), but sonographic data comparing NIFTP to PTC and FA is lacking...
November 29, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29193882/giant-cell-tumor-of-temporomandibular-joint-presenting-as-a-parotid-tumor-challenges-in-the-accurate-subclassification-of-giant-cell-tumors-in-an-unusual-location
#13
Rongqin Ren, Sandra Mueller, Adele O Kraft, Celeste N Powers
Fine needle aspiration is frequently used as the initial diagnostic procedure in the work-up of head and neck lesions, including soft tissue masses and salivary gland neoplasms. Giant cell tumors (GCTs), both osseous and extraosseous, are benign tumors that occur, albeit rarely, in the head and neck region. Extraosseous GCTs may be further classified based on their tissue of origin and specific anatomic location. Regardless of location, giant cell tumors are morphologically similar and share cytologic and histologic diagnostic criteria...
November 30, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29193839/implementing-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-may-potentially-impact-the-risk-of-malignancy-for-thyroid-nodules-categorized-as-aus-flus-and-fn-sfn
#14
Weihong Li, Andrew Sciallis, Madelyn Lew, Judy Pang, Xin Jing
BACKGROUND: Noninvasive encapsulated follicular variant of papillary thyroid carcinoma (PTC) has recently been reclassified as noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Implementation of the new terminology may alter the implied risk of malignancy (ROM) across the six categories of The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). METHODS: The study cohort consisted of thyroid fine needle aspiration (FNA) cases which were assessed between January 2011 and June 2016 and led to surgical resections...
November 30, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29193813/a-case-report-of-brown-tumor-in-a-patient-with-chronic-renal-failure-and-renal-cell-carcinoma
#15
Yong-Jun Liu, Elizabeth E Frauenhoffer, Eric Walker, Nicole C Williams
We report a case of a 72 year old male with hyperparathyroidism secondary to end stage diabetic renal disease and coexisting bilateral chromophobe renal cell carcinomas. The patient presented with back and groin pain, right pelvic hemorrhage, and multiple lytic bone lesions concerning for metastatic renal cell carcinoma. Fine needle aspiration cytology demonstrated benign appearing osteoclasts and spindled cells. A concurrent core biopsy showed foci of spindled cell proliferation populated by osteoclast-like giant cells with stromal hemorrhage without evidence of metastatic carcinoma...
November 29, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29193804/primary-cutaneous-aspergillosis-mimicking-malignancy-a-rare-presentation-in-an-immunocompetent-patient
#16
Rachana Chaturvedi, Ashvini Kolhe, Kirti Pardeshi, Leena Naik, Shashir Wanjare
Aspergillus species are ubiquitous opportunistic molds that cause both allergic and invasive syndromes. A 65-year-old female, farmer by occupation, presented with left upper limb and trunk swelling for one year, associated with pain, tightening of skin, and vesicles with watery discharge. Local examination showed a diffuse swelling extending from left arm to forearm and lateral chest wall associated with edema, induration, and raised temperature. The swelling was firm to hard with superficial skin ulcers and black eschar...
November 30, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29187888/advantage-of-pet-ct-in-target-delineation-of-mri-negative-cervical-lymph-nodes-in-intensity-modulated-radiation-therapy-planning-for-nasopharyngeal-carcinoma
#17
Guanzhu Shen, Weiwei Xiao, Fei Han, Wei Fan, Xiao-Ping Lin, Lixia Lu, Lie Zheng, Ning Yue, Bruce Haffty, Chong Zhao, Xiaowu Deng
Introduction: In intensity-modulated radiation therapy (IMRT) planning for nasopharyngeal carcinoma (NPC), cervical lymph nodes (CLNs) that appear negative on magnetic resonance imaging (MRI) scans can be difficult to target. The purpose of this study was to assess the advantage of 18F-fluorodeoxyglucose positron emission tomography with computed tomography (18F-FDG PET/CT) for distinguishing MRI-negative CLNs and the effect of 18F-FDG PET/CT on diagnosis, target delineation, and dose prescription in IMRT planning for NPC...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/29182368/fine-needle-aspiration-biopsy-of-thyroid-nodule-smaller-than-1-0-cm-accuracy-of-tirads-classification-system-in-more-than-1000-nodules
#18
Guilherme F Mendes, Marcio Rt Garcia, Priscila M Falsarella, Antonio Rahal, Francisco A Cavalcante, Daniela R Nery, Rodrigo G Garcia
OBJECTIVE: The aim of identify whether the same ultrasound features can be applied and should be considered to support the decision as to which subcentimetric nodules should be biopsied with FNAB. METHODS: Uni-institutional, IRB approved, retrospective study conducted from 2008 to 2016, that evaluated 1094 thyroid nodules smaller than 1.0cm classified according TIRADS and submitted to fine needle aspiration (FNAB). RESULTS: The value of fine needle aspiration biopsy (FNAB) of thyroid nodules smaller than 1...
November 28, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29179883/shifting-trend-of-tubercular-lymphadenitis-over-a%C3%A2-decade-a-study-from-eastern-region-of-india
#19
Senjuti Dasgupta, Sudipta Chakrabarti, Supriya Sarkar
BACKGROUND: The incidence of tuberculosis (TB) is changing in India. The commonest extra pulmonary manifestation of TB is tuberculous lymphadenitis. AIMS AND OBJECTIVES: To detect changes in occurrence of TB lymphadenitis by comparing current data with that from 10 years back. METHODS: Fine Needle Aspiration Cytology (FNAC) findings of patients presenting with lymphadenopathy between January 2014 and December 2015 were included in the study as current data...
October 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29178587/self-clotting-method-improves-cell-block-preparation
#20
Yan Shi, Jeanine Chiaffarano, Melissa Yee-Chang, Tamar C Brandler, Paul Elgert, Allen Leung, Xiao-Jun Wei, Joan Cangiarella, Aylin Simsir, Wei Sun
BACKGROUND: The success of cell block preparation is crucial for ancillary diagnostic tests in cytology. However, achieving an optimal cell block can be challenging. The current study describes a self-clotting-based technique for fine-needle aspiration (FNA) cell block preparations and evaluates its usefulness in comparison with the conventional needle wash technique. METHODS: The clinical data, FNA procedure, and cellularity of cell blocks of the self-clotting group (37 cases) and the conventional needle wash group (33 cases) were compared...
November 27, 2017: Cancer
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