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Fine needle aspiration cytology

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https://www.readbyqxmd.com/read/28218194/role-of-contrast-enhanced-endoscopic-ultrasound-in-lymph-nodes
#1
REVIEW
Michael Hocke, Andre Ignee, Christoph Dietrich
Diagnosing unclear lymph node (LN) enlargements in the mediastinum and abdomen is the most important indication of endoscopic ultrasound (EUS)-fine needle aspiration (FNA) after the diagnosis and treatment of pancreatic diseases. Investigating LNs in these areas can happen in different clinical settings. Mostly, it is the first modality in general LN diseases without any peripheral LN enlargements. On the other hand, it can be the question of LN involvement in a known or suspected primary tumor. Due to EUS-FNA cytology, those questions can be answered highly, accurately...
January 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28217985/two-unusual-variants-of-pancreatic-neuroendocrine-tumor-and-their-potential-pitfalls-on-fine-needle-aspiration-cytology
#2
Abby M Richmond, Sanjana Mehrotra
Endoscopic ultrasound-guided fine-needle aspiration is increasingly utilized for the diagnosis of pancreatic lesions. Although operator dependent, the procedure has good overall performance characteristics and is minimally invasive; however, accuracy and sensitivity are reportedly lower for pancreatic neuroendocrine tumor (PanNET) compared with the more common pancreatic ductal adenocarcinoma (pACA). The underperformance is further exacerbated by the unusual cases of PanNET presenting with variant cytomorphology...
February 20, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28217980/reproducibility-of-atypia-of-undetermined-significance-follicular-lesion-of-undetermined-significance-category-using-the-bethesda-system-for-reporting-thyroid-cytology-when-reviewing-slides-from-different-institutions-a-study-of-interobserver-variability-among
#3
Vijayalakshmi Padmanabhan, Carrie B Marshall, Guliz Akdas Barkan, Mohiedean Ghofrani, Alice Laser, Idris Tolgay Ocal, Charles David Sturgis, Rhona Souers, Daniel F I Kurtycz
BACKGROUND: The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) offers a six-tiered diagnostic scheme for thyroid Fine Needle Aspiration (FNA): Benign, Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance (AUS/FLUS), suspicious for follicular neoplasm, suspicious for malignancy, malignant, and unsatisfactory with an aim to standardize diagnostic criteria. Reported rate of AUS/FLUS category in the literature has varied from 3% to 20.5%. METHODS: The aim of this study was to assess interobserver variability among cytopathologists to assess reproducibility of the AUS/FLUS category...
February 20, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28217964/is-fine-needle-aspiration-really-not-necessary-in-patients-with-thyroid-nodules%C3%A2-%C3%A2-%C3%A2-1-cm-with-highly-suspicious-features-on-ultrasonography-and-candidates-for-active-surveillance
#4
Pedro Weslley Rosario, Alexandre Lemos Silva, Maria Regina Calsolari
BACKGROUND: The low rate of progression associated with the potential complications of thyroidectomy makes active surveillance an increasingly recommended management in low-risk papillary microcarcinomas of the thyroid (PMT). The objective of this study was to report the results of fine needle aspiration (FNA) of nodules ≤ 1 cm with highly suspicious appearance on ultrasonography (US) in patients who are potential candidates for active surveillance. METHODS: We revised thyroid nodules ≤ 1 cm with highly suspicious appearance on US in patients without known distant metastases, suspicion of extrathyroid extension, or suspicious lymph nodes on US...
February 20, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28217853/use-of-cytological-samples-of-metastatic-melanoma-for-ancillary-studies
#5
H M Ko, M A Saieg, G da Cunha Santos, S Kamel-Reid, S L Boerner, W R Geddie
OBJECTIVE: Fine needle aspiration (FNA) is widely used in the diagnosis of metastatic melanoma, both at initial presentation and in the setting of recurrent disease. The purpose of this study was to evaluate the performance of confirmatory immunohistochemistry (IHC) and molecular analysis of the BRAF mutation in cytological preparations of metastatic melanoma. METHODS: A 2-year retrospective review of pathology reports was performed on cytological samples of metastatic melanoma at the University Health Network (Toronto, Canada) and the Santa Casa Medical School (Sao Paulo, Brazil)...
February 20, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28217141/primary-orbital-mantle-cell-lymphoma-flow-cytometric-immunophenotyping-as-an-adjunct-to-fine-needle-aspiration-cytology-for-diagnosis
#6
Sangeeta Verma, Nalini Gupta, Satyawati Mohindra, Manupdesh Singh Sachdeva, Arvind Rajwanshi
No abstract text is available yet for this article.
2017: CytoJournal
https://www.readbyqxmd.com/read/28217140/evaluation-of-polymerase-chain-reaction-in-space-occupying-lesions-of-liver-reported-as-granulomatous-inflammation-tuberculosis-on-fine-needle-aspiration-cytology
#7
Kusum Sharma, Nalini Gupta, Kapil Goyal, Ajay Kumar Duseja, Aman Sharma, Arvind Rajwanshi
BACKGROUND: Tubercular involvement of the liver is uncommon, but is a serious consideration in differential diagnosis of granulomatous conditions, especially in endemic regions like India. OBJECTIVE: To assess the role of polymerase chain reaction (PCR) done on archival cytological material in diagnosing tuberculosis (TB) in cases reported as granulomatous inflammation/TB in liver lesions. MATERIALS AND METHODS: This was a retrospective study including a total of 17 cases of liver space-occupying lesions (SOLs) reported as granulomatous inflammation (n = 12) and TB (n = 5)...
2017: CytoJournal
https://www.readbyqxmd.com/read/28216872/thyroid-mass-metastasis-from-nasopharyngeal-cancer-an-unusual-presentation
#8
Shirley C Lewis, Anil K D'cruz, Amit Joshi, Rajiv Kumar, Shubhada V Kane, Sarbani Ghosh Laskar
Thyroid gland is an uncommon site of metastasis, and metastasis to the gland secondary to nasopharyngeal carcinoma is seldom seen. We were only able to identify eight reported cases in the literature. A 61-year-old man, diagnosed case of nasopharyngeal cancer-second primary ( first primary-oropharynx), was found to have a thyroid nodule on routine follow-up positron emission tomography-computed tomography (PET-CT) scan. There was no evidence of metastases at any other sites. The thyroid nodule was confirmed as metastatic carcinoma by fine needle aspiration cytology...
January 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/28211232/thyroid-fine-needle-aspiration-cytology-mimicking-thyroid-papillary-cancer-in-a-lung-cancer-patient
#9
Chih-Yu Hsu, Ching-Ling Lin, Ming-Lin Tsai, Shih-Hung Huang
No abstract text is available yet for this article.
March 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28208863/fine-needle-aspiration-cytology-of-papulonodular-lesions-of-skin-a-study-of-50-cases
#10
Sapna Patel, Asha Mahadevappa, Gubbanna Vimalambike Manjunath
INTRODUCTION: Skin is one of the frequent site of disease in human body. Fine Needle Aspiration Cytology (FNAC) is a safe diagnostic method in these cases. FNAC has some limitation, particularly related to representativity of samples, exact typing of skin adnexal tumours and classifying the nature of metastatic cutaneous nodules. Thus, FNAC alone may not give a confirmative diagnosis regarding few skin lesions. Hence, histopathological study has been the standard technique for the diagnosis of skin lesions...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28205384/cribriform-adenocarcinoma-of-the-minor-salivary-gland-arising-in-the-tonsil-with-metastasis-to-a-cervical-lymph-node-a-case-report-with-description-of-fine-needle-aspiration-cytology
#11
Alexa Pagano, Katie Dennis
Cribriform adenocarcinoma of minor salivary gland (CAMSG) is a rare tumor of the head and neck. We report a case of a 70-year-old female who presented with a 4-5-month history of a left neck mass. CT scan of the neck showed a left neck mass just inferior to the angle of the mandible and left tonsillar prominence. Fine-needle aspiration (FNA) of the neck mass showed epithelial groups with focal cribriform architecture. The cells had round to oval nuclei and fine chromatin. The background contained scattered lymphocytes...
February 16, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28201927/histologic-findings-and-cytological-alterations-in-thyroid-nodules-after-radioactive-iodine-treatment-for-graves-disease
#12
Siba El Hussein, Yumna Omarzai
Unlike the well-documented relation between radiation to the neck and development of papillary thyroid carcinoma, a causal association between radioactive iodine treatment for Graves' disease and development of thyroid malignancy is less defined. However, patients with a background of thyroid dysfunction presenting with clinically palpable thyroid nodules are followed more closely than the average population, and fine needle aspiration is recommended in such circumstances. Cytological examination of aspirates, and histologic examination of tissue provided from patients with a known history of Graves' disease, managed by radioactive iodine therapy can create a diagnostic dilemma, as the distinction between radiation effect and a malignant primary thyroid neoplasm can be very challenging...
February 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28198060/fine-needle-aspiration-cytology-from-a-postauricular-swelling
#13
P Ramteke, S Mallick, S Mathur, D Jain, V K Iyer
No abstract text is available yet for this article.
February 14, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28195253/diagnostic-role-of-detecting-hpv-in-a-fnac-of-metastatic-laterocervical-lymph-node-in-a-case-of-occult-hpv-related-head-and-neck-squamous-cell-carcinoma
#14
A Ginori, F Scaramuzzino, M A G Munezero Butorano, A Barone, A Disanto
Human papillomavirus (HPV)-related head and neck squamous cell carcinomas (HNSCC) are radiosensitive tumors and have a better prognosis than the conventional keratinizing HNSCC. Despite extensive radiographic and clinical evaluation in approximately 3% to 5% of patients who present with cervical lymph node metastases, the primary tumor remains occult. The lack of a clinically identifiable primary tumor usually leads to more aggressive therapy, which can result in higher morbidity. Herein, we report a case of a patient with an occult HPV-related HNSCC, diagnosed detecting HPV in a fine needle aspiration cytology (FNAC) of metastatic laterocervical lymph nodes...
June 2016: Pathologica
https://www.readbyqxmd.com/read/28192645/cytological-molecular-and-clinical-features-of-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-versus-invasive-forms-of-follicular-variant-of-papillary-thyroid-carcinoma
#15
Liena Zhao, Dora Dias-Santagata, Peter M Sadow, William C Faquin
BACKGROUND: The noninvasive follicular variant of papillary thyroid carcinoma (PTC) has an indolent clinical behavior in comparison with other PTCs, including the invasive follicular variant of papillary thyroid carcinoma (IFVPTC). Recently, the term noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was introduced to emphasize the low biological potential of these tumors. This study compares clinical, cytological, and molecular features of NIFTP and IFVPTC...
February 13, 2017: Cancer
https://www.readbyqxmd.com/read/28192631/thyroid-cytology-nuclear-versus-architectural-atypia-within-the-atypia-of-undetermined-significance-follicular-lesion-of-undetermined-significance-bethesda-category-have-significantly-different-rates-of-malignancy
#16
Tiffany Rui Xuan Gan, Min En Nga, Jeffrey Huey Yew Lum, Wendy Meihua Wong, Wee Boon Tan, Rajeev Parameswaran, Kee Yuan Ngiam
BACKGROUND: The Bethesda System for Reporting Thyroid Cytopathology is the most widely used classification system for the reporting of thyroid fine-needle aspiration cytology (FNAC) specimens. However, the "atypical" category ("atypia of undetermined significance" [AUS] or "follicular lesion of undetermined significance" [FLUS]) continues to cause diagnostic and therapeutic dilemmas. The objectives of this study were to describe the differential malignancy rates of FNACs diagnosed as AUS/FLUS based on nuclear or architectural atypia and to assess the significance of demographic and ultrasonographic features in predicting malignancy in this category...
February 13, 2017: Cancer
https://www.readbyqxmd.com/read/28191725/unusual-location-of-primary-hydatid-cyst-diagnosed-on-aspiration-cytology
#17
Rikki Singal, Amit Mittal, Monika Garg, Muzzafar Zaman, Manish Chaudhry, Samita Singal, Bhanu Pratap Sharma
Hydatid cyst (HC) is a parasitic infection caused by Echinococcus granulosus. It occurs frequently in liver and lungs. Hydatid cyst of neck is extremely rare occurrence, and here, we report it with this unusual location. A 25-year-old male nonhypertensive and nondiabetic presented with slowly growing painless swelling in right side of neck for 4-5 years. The swelling measured 5 × 3 cm and was of soft to firm consistency. Fine needle aspiration cytology yielded fluid aspirate and smear showed features suggestive of HC...
February 13, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28185442/the-role-of-ancillary-tests-in-the-evaluation-and-management-of-patients-with-negative-and-non-diagnostic-pancreatic-cyst-aspirates
#18
Suzanne M Selvaggi
BACKGROUND: Fine needle aspiration of pancreatic cystic lesions has its limitations as the cytology is often paucicellular to acellular. This study reports on the value of ancillary tests, amylase and carcinoembryonic, in the evaluation and management of patients with negative and non-diagnostic pancreatic cysts. METHODS: From January 1, 2010 through December 31, 2015, the Cytopathology Laboratory processed 119 pancreatic cyst aspirates of which 51(43%) were negative and 52(44%) were non-diagnostic and form the basis of this study...
February 10, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28185421/fine-needle-aspiration-findings-of-xp11-translocation-renal-cell-carcinoma-metastatic-to-a-hilar-lymph-node
#19
Reima El Naili, Marlo Nicolas, Amanda Gorena, Maria Luisa C Policarpio-Nicolas
Xp11 translocation renal cell carcinoma (RCC) is a specific type of renal cell carcinoma recently placed under the "MiT family translocation RCC" at the last 2013 ISUP Vancouver classification of renal neoplasia. This tumor contains variable proportions of clear cells and could easily mimic papillary RCC, clear cell type, and clear cell papillary RCC. Given the small number of published cytologic findings of this tumor, it could easily present as a diagnostic pitfall. We describe a case of a 23-year-old man with a history of prior nephrectomy who presented with multiple mediastinal lymphadenopathies on imaging surveillance follow-up...
February 10, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28184253/concordance-between-the-tirads-ultrasound-criteria-and-the-bethesda-cytology-criteria-on-the-nontoxic-thyroid-nodule
#20
Hernando Vargas-Uricoechea, Ivonne Meza-Cabrera, Jorge Herrera-Chaparro
BACKGROUND: Thyroid nodule is a common disorder of the thyroid. Despite their benign nature, they can be associated with multiple pathologic conditions, including thyroid cancer. METHODS: This cross-sectional study determined the concordance of Ultrasound (TIRADS criteria) and Fine Needle Aspiration Biopsy (FNA-BETHESDA system) in the assessment of the nontoxic thyroid nodule. A total of 180 subjects 18 years old or older underwent the two diagnostic tests and their results were compared using kappa index...
2017: Thyroid Research
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