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Fine needle aspiration cytology

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https://www.readbyqxmd.com/read/28100949/rosai-dorfman-disease-presenting-with-recurrent-unilateral-submandibular-lymph-adenitis-a-case-report
#1
Vipan Kumar, J S Bhandari, Sukirty Awasthi, Mohammad Rashid, Ankita Sharma
Rosai-Dorfman Disease (RDD) is a rare disease of unknown aetiology, initially described as a separate entity in 1969 by Rosai and Dorfman. We describe here a case of RDD presenting with acute, recurrent lymphadenitis and massive lymphadenopathy. The patient's good response to the antibiotics was a false pointer towards infective pathology. The repeated fine needle aspiration cytology was inconclusive or suggested nonspecific reactive hyperplasia. The excision biopsy confirmed the diagnosis of RDD and was supported by immune-histochemistry for S-100 antigen...
December 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28094897/cytology-assessment-can-predict-survival-for-patients-with-metastatic-pancreatic-neuroendocrine-neoplasms
#2
Carlie S Sigel, Huimin Guo, Keith M Sigel, Ming Zhang, Natasha Rekhtman, Oscar Lin, David S Klimstra, Achim A Jungbluth, Laura K Tang
BACKGROUND: Histological features and Ki-67 index have known usefulness in predicting prognosis and guiding therapy among patients with metastatic pancreatic neuroendocrine neoplasms. Fine-needle aspiration may offer advantages for Ki-67 assessment because the technique obtains highly cellular, well-preserved specimens with the potential for broader tumor sampling. In the current study, the authors evaluated concordance for grade and differentiation between concurrent core needle biopsy and cytology preparations...
January 17, 2017: Cancer
https://www.readbyqxmd.com/read/28094066/implementation-of-elastography-score-and-strain-ratio-in-combination-with-b-mode-ultrasound-avoids-unnecessary-biopsies-of-breast-lesions
#3
Kristina Bojanic, Natasa Katavic, Martina Smolic, Marija Peric, Kristina Kralik, Miroslav Sikora, Kristina Vidačić, Mirta Pacovski, Damir Stimac, Gordana Ivanac
The aim of this study was to evaluate whether the combination of B-mode ultrasound, elastography score (ES) and strain ratio (SR) improves diagnostic performance with respect to breast lesions. One hundred thirty lesions were prospectively evaluated by B-mode ultrasound and strain elastography, followed by fine-needle aspiration cytology/biopsy in 117 woman who were scheduled for regular breast BUS. The median ES (4.5 vs. 2.9, p < 0.001) and SR (4.9 vs. 2.3, p < 0.001) were significantly higher for malignant than for benign lesions...
January 13, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28081315/the-association-of-papillary-thyroid-cancer-with-microcalcification-in-thyroidnodules-with-indeterminate-cytology-based-on-fine-needle-aspiration-biopsy
#4
İbrahim Ali Özemir, Barış Bayraktar, Ender Anılır, Kıvılcım Orhun, Tunç Eren, Jülide Sağıroğlu, Ayşe Bahar Ceyran, Rafet Yiğitbaşı, Orhan Alimoğlu
BACKGROUND/AIM: Microcalcifications are generally accepted as highly specific for thyroid malignancy, especially for papillary thyroid carcinoma (PTC). The aim of this study was to determine the significance of microcalcification within nodules that were classified as being of “indeterminate cytology” (IC) according to fine-needle aspiration biopsy. MATERIALS AND METHODS: Patients who underwent thyroidectomy between January 2010 and 2013 were included in the study...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28078879/zenker-diverticulum-in-the-right-side-of-the-neck-resembling-a-thyroid-mass-at-ultrasound
#5
S Alessandrini, I Samperi, F De Cristofaro, E D'Armiento, D Diacinti, A Pernazza, D Bosco, V Ascoli, S Ulisse
Zenker’s diverticulum represents the most common form of pharyngo-oesophageal diverticula usually occurring on the left side of the neck. Due to its anatomical proximity to the thyroid, it can mimic a thyroid mass. Here we describe the case of an asymptomatic 49-year-old man referred to the Thyroid Clinic of the Policlinico Umberto I Hospital-“Sapienza” University of Rome for thyroid sonography due to a family history of autoimmune thyroid disease. The patient’s thyroid blood tests did not reveal any abnormalities...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28078873/fine-needle-aspiration-cytology-of-650-thyroid-nodules-operated-for-multinodular-goiter-a-cyto-histological-correlation-based-on-the-new-italian-cytological-classification-siapec-2014
#6
F Tartaglia, A Giuliani, L Tromba, S Carbotta, M Karpathiotakis, G Tortorelli, F Pelle, R Merola, C Donello, G Carbotta, L De Anna, G Conzo, S Sorrenti, S Ulisse
The new Italian cytological classification (SIAPEC 2014) of thyroid nodules, in line with those of Bethesda and BTA-RCPath, replaces the previous TIR3 class with two new classes (TIR3A and TIR3B), which correspond to different risks of malignancy and clinical actions required. The present study was conducted to evaluate the diagnostic accuracy of the new SIAPEC classification as opposed to its previous version (SIAPEC 2007). Preoperative cytology was compared with the final histology obtained from 650 consecutive patients who underwent total thyroidectomy for multinodular goiter...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28076460/the-accuracy-of-fine-needle-aspiration-cytology-for-diagnosis-of-parotid-gland-masses-a-clinicopathological-study-of-114-patients
#7
Jens Kristjan Gudmundsson, Aida Ajan, Jahan Abtahi
Objective: Fine-needle aspiration cytology is a valuable method for preoperative assessment of head and neck tumors. However, its accuracy in detection of salivary gland masses is controversial compared with other methods. The aim of this work was to evaluate the effectiveness and accuracy of fine-needle aspiration cytology (FNAC) in the diagnosis of parotid gland masses. Material and Methods: Over a 10-year period, 126 parotid gland masses were resected. Retrospective chart reviews of 114 patients were performed...
November 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28072692/role-of-biochemistry-and-cytological-analysis-of-cyst-fluid-for-the-differential-diagnosis-of-pancreatic-cysts-a-retrospective-cohort-study
#8
Ozlem Mutluay Soyer, Bulent Baran, Asli Ciftcibasi Ormeci, Davut Sahin, Suut Gokturk, Sami Evirgen, Rafet Basar, Pinar Firat, Filiz Akyuz, Kadir Demir, Fatih Besisik, Sabahattin Kaymakoglu, Cetin Karaca
BACKGROUND: Management of pancreatic cysts is based on neoplastic-nonneoplastic discrimination. Endoscopic ultrasound (EUS) enables to differentiate neoplastic-nonneoplastic lesions and also allows fine-needle aspiration (FNA). In this study, we aim to assess feasibility and clinical relevance of cytological and biochemical analysis in differential diagnosis of cystic pancreatic lesions in patients who had undergone endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) due to pancreatic cysts...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28071986/evaluation-of-a-two-year-routine-application-of-molecular-testing-of-thyroid-fine-needle-aspirations-fna-using-a-7-gene-panel-in-a-primary-referral-setting-in-germany
#9
Markus Eszlinger, Katharina Böhme, Maha Ullmann, Fabian Görke, Udo Siebolts, Anna Neumann, Christiane Franzius, Sabine Adam, Thomas Molwitz, Christian Landvogt, Bassam Amro, Anja Hach, Berit Feldmann, Dieter Graf, Antje Wefer, Rainer Niemann, Catharina Bullmann, Günther Klaushenke, Reinhard Santen, Gregor Tönshoff, Velimir Ivancevic, Andreas Kögler, Eberhard Bell, Bernd Lorenz, Gerald Kluge, Christoph Hartenstein, Ilka Ruschenburg, Ralf Paschke
BACKGROUND: Major differences with respect to the diagnostic performance of a "ruling in" approach in the pre-surgical diagnosis of indeterminate thyroid fine needle aspirations (FNAs) have been reported. Therefore, the aim of this prospective multicenter study was to investigate the specific diagnostic impact of mutation testing using a 7-gene-panel in a routine primary referral setting analyzing FNAs from endocrinology and nuclear medicine practices in Germany. METHODS: RNA and DNA was extracted from 564 routine air-dried FNA smears obtained from 64 physicians and cytologically graded by one experienced cytopathologist...
January 10, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28067962/concurrent-multiple-myeloma-and-mast-cell-neoplasia-in-a-13-year-old-castrated-male-maine-coon-cat
#10
Jonathan M Bagwell, Heather R Herd, Melanie A Breshears, Steven Hodges, Theresa E Rizzi
A 13-year-old, castrated male Maine Coon cat was presented to Oklahoma State University Boren Veterinary Medical Teaching Hospital for yearly echocardiographic examination monitoring hypertrophic cardiomyopathy (HCM) diagnosed in 2003. Physical examination revealed a heart murmur and premature beats, likely related to HCM, but was otherwise unremarkable. A biochemistry profile revealed a hyperglobulinemia (6.3 g/dL). Cytologic examination of fine-needle aspirates from liver and spleen revealed increased numbers of plasma cells and mast cells, confirmed with subsequent histologic examination...
January 9, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28065639/imaging-features-and-diagnosis-of-tuberculosis-of%C3%A2-the-breast
#11
C F Longman, T Campion, B Butler, T D Suaris, A Khanam, H Kunst, S Tiberi, S A O'Keeffe
AIM: To outline the pathophysiology, clinical presentation, imaging features, and relevant investigations of the different subtypes of breast tuberculosis (TB). MATERIALS AND METHODS: A review was undertaken of all cases (33 in total) of breast TB presenting to Barts Health NHS Trust within a 10-year period, including patient demographics, imaging features, and route of diagnosis. RESULTS: Thirty-three cases of proven granulomatous TB of the breast were identified (11 mastitis obliterans, 10 nodular caseous form, five sclerosing form, four disseminated disease, and three abnormal axillary lymph nodes)...
January 6, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28061860/preliminary-investigation-of-the-transmission-of-tuberculosis-between-farmers-and-their-cattle-in-smallholder-farms-in-northwestern-ethiopia-a-cross-sectional-study
#12
Anwar Nuru, Gezahegne Mamo, Aboma Zewude, Yitayal Mulat, Gashaw Yitayew, Aschalew Admasu, Girmay Medhin, Rembert Pieper, Gobena Ameni
BACKGROUND: The feeding habits and close physical contact between Ethiopian farmers and their cattle promote the transmission of tuberculosis (TB) between the farmers and their cattle. This study aimed to investigate the transmission of TB between farmers and their cattle in smallholder farms in northwestern Ethiopia. RESULTS: A total of 70 human TB lymphadenitis (TBLN) cases visiting the Felegehiwot Comprehensive Specialized Hospital in Bahir Dar City and 660 cattle were investigated...
January 7, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28053701/primary-thyroid-lymphoma-a-case-report-and-review-of-the-literature
#13
Rita Peixoto, João Correia Pinto, Virgínia Soares, Pedro Koch, António Taveira Gomes
INTRODUCTION: A rapidly enlarging mass of the anterior compartment of the neck with compressive symptoms may represent, among other diagnosis, a neoplasm of the thyroid gland. PRESENTATION OF CASE: We describe the case of a 59-year-old woman referred to the endocrine surgical unit because of compressive cervical symptoms for 3 months. The cervical ultrasound revealed a sub-sternal goiter with heterogeneous echo structure and the fine-needle aspirating cytology was inconclusive...
January 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28050442/pancreatic-tuberculosis-a-puzzle-for-physicians-a-rare-case-and-review-of-literature
#14
Prashanth Ashok Kumar, Gursharan Singh, John Biku Joseph, S Swaminathan, L Venkatakrishnan
Pancreatic Tuberculosis is an uncommon form of extra pulmonary tuberculosis that resembles malignancy of pancreas and serve as a diagnostic challenge for physicians. Conservative management with Anti Tuberculosis Therapy (ATT) will suffice for pancreatic tuberculosis whereas a malignancy may require major surgeries which may lead to significant morbidity. Here, we discuss the case of a female patient who presented with abdominal pain and vomiting and is a known case of chronic calcific pancreatitis. Radiological findings were that of malignancy of the pancreas...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28050379/pulmonary-hamartoma-mimicking-malignancy-a-cytopathological-diagnosis
#15
Manjari Kishore, Prajwala Gupta, Preeti, Desh Deepak
Pulmonary Hamartomas (PH) are benign tumour-like lesions of lung with an uncommon occurrence and pose a diagnostic challenge on chest radiograph. Fine Needle Aspiration Cytology (FNAC) can lead to a definitive diagnosis as well as distinguishes these from malignant lung mass. Most of the patients are asymptomatic and incidentally detected on routine chest radiographs. We report a case of pulmonary hamartoma where the patient was symptomatic and a possibility of malignant neoplasm was considered until the FNAC concluded the diagnosis...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28044305/clinicopathological-analysis-of-mediastinal-masses-a-mixed-bag-of-non-neoplastic-and-neoplastic-etiologies
#16
Preeti Sharma, Vidya Jha, Naveen Kumar, Rohit Kumar, Ashish Mandal
OBJECTIVE: The mediastinum is the central portion of the thoracic cavity, housing numerous organs and harbouring a mixed bag of non-neoplastic and neoplastic lesions. Accurate diagnosis is essential owing to the widely variable therapeutic and prognostic implications. MATERIAL AND METHOD: Cases of mediastinal masses were retrospectively reviewed from January 2011 till January 2016. Clinico-radiological records of these cases were retrieved. Fine needle aspiration cytology (FNAC) was performed wherever feasible...
2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28042980/extensive-regional-metastasis-of-high-grade-mucoepidermoid-carcinoma-of-an-unknown-primary%C3%A2-tumor
#17
Naseem Ghazali, Alyssa Flashburg, Robert A Ord
PURPOSE: Mucoepidermoid carcinoma (MEC) is the most common salivary carcinoma. It arises most frequently in the major salivary glands but can also arise in minor glands or intraosseous sites. MEC of an unknown primary occurs very rarely. The present report documents only the third case reported in medical studies. METHODS: A 66-year-old man with previous carcinoma in situ (CIS) of the left posterior oral tongue that had been excised in 2004 and again in 2010 presented with a hard lymph node, 3 × 2 cm at level II of the right neck in July 2015...
December 15, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28042957/papanicolaou-society-of-cytopathology-new-guidelines-have-a-greater-ability-of-risk-stratification-for-pancreatic-endoscopic-ultrasound-guided-fine-needle-aspiration-specimens
#18
Bo Chen, Yu Zhao, Jiangang Gu, Huanwen Wu, Zhiyong Liang, Zhilan Meng
The Papanicolaou Society of Cytopathology has recently proposed a standardized terminology and nomenclature guidelines for pancreatic cytology. However the risk of malignancy associated with the new guidelines has been scarcely studied. In this study, a series of pancreatic cytology cases obtained by endoscopic ultrasound-guided fine-needle aspiration from 294 Chinese patients were retrospectively re-categorized into six categories according the new guidelines. The risks of malignancy were 18.1% for "negative," 20...
December 22, 2016: Oncotarget
https://www.readbyqxmd.com/read/28042209/comparison-of-immunocytochemistry-and-immunohistochemistry-on-breast-carcinoma-a-boon-or-a-bane
#19
Kempula Geethamala, Venkataramappa Srinivasa Murthy, Bangalore Ramalingiah Vani, Madireddi Sudha Rao, Malugnalli Uddappa Thejaswini, Krishnarajapet Padmanabha Padmaja
INTRODUCTION: Breast carcinoma is the most common cancer among women in the urban Indian population. Conventionally, immunohistochemistry (IHC) is done to determine the hormone receptor status of the tumor. Immunocytochemistry (ICC) on fine-needle aspiration cytology (FNAC) was carried out to determine the same hormone receptor status of the tumor. OBJECTIVE: The study was undertaken to evaluate the diagnostic reliability of performing estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (Her2/neu) receptor status on FNAC by ICC and to compare the results with IHC...
January 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28041586/thyroid-nodules-%C3%AE-guide-to-assessment-treatment-and-follow-up
#20
REVIEW
Stavroula Α Paschou, Andromachi Vryonidou, Dimitrios G Goulis
Thyroid nodules constitute by far the most common disorder of the endocrine system. Epidemiological studies have indicated that approximately 5% of women and 1% of men resident in iodine-sufficient areas have palpable thyroid nodules. However, by the age of 60 years about 50% of the general population is estimated to have at least one thyroid nodule. Indeed, the reported prevalence of a "thyroid incidentaloma" is up to 70% when neck/carotid artery ultrasound, computed tomography (CT) or magnetic resonance imaging (MRI) is performed for other indications...
February 2017: Maturitas
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