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https://www.readbyqxmd.com/read/29141696/use-of-a-trigger-tool-to-detect-adverse-drug-reactions-in-an-emergency-department
#1
Silvana Maria de Almeida, Aruana Romualdo, Andressa de Abreu Ferraresi, Giovana Roberta Zelezoglo, Alexandre R Marra, Michael B Edmond
BACKGROUND: Although there are systems for reporting adverse drug reactions (ADR), these safety events remain under reported. The low-cost, low-tech trigger tool method is based on the detection of events through clues, and it seems to increase the detection of adverse events compared to traditional methodologies. This study seeks to estimate the prevalence of adverse reactions to drugs in patients seeking care in the emergency department. METHODS: Retrospective study from January to December, 2014, applying the Institute for Healthcare Improvement (IHI) trigger tool methodology for patients treated at the emergency room of a tertiary care hospital...
November 15, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29134155/foliar-microbiome-transplants-confer-disease-resistance-in-a-critically-endangered-plant
#2
Geoffrey Zahn, Anthony S Amend
There has been very little effort to incorporate foliar microbiomes into plant conservation efforts even though foliar endophytes are critically important to the fitness and function of hosts. Many critically endangered plants that have been extirpated from the wild are dependent on regular fungicidal applications in greenhouses that cannot be maintained for remote out-planted populations, which quickly perish. These fungicides negatively impact potentially beneficial fungal symbionts, which may reduce plant defenses to pathogens once fungicide treatments are stopped...
2017: PeerJ
https://www.readbyqxmd.com/read/29119824/an-innovative-health-care-delivery-model-for-children-with-medical-complexity
#3
Anne Elizabeth Glassgow, Molly A Martin, Rachel Caskey, Melishia Bansa, Michael Gerges, Mary Johnson, Monika Marko, Kenita Perry-Bell, Heather J Risser, Peter J Smith, Benjamin Van Voorhees
Children with medical complexity (CMC) account for a disproportionate share of pediatric health-care utilization and cost that is largely attributable to long hospitalizations, frequent hospital readmissions, and high use of emergency departments. In response, the Centers for Medicare and Medicaid Services Health Care Innovation Center supports the development and testing of innovative health-care payment and service delivery models. The purpose of this article is to describe the CMS-funded coordinated health care for complex kids (CHECK) program, an innovative system of health-care delivery that provides improved, comprehensive, and well-coordinated services to CMC...
September 2017: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29114623/the-use-of-a-high-tech-knee-pad-for-reduction-of-the-postoperative-effusion-after-total-knee-arthroplasty
#4
Massimo Innocenti, Michele Mancini, Marina Faccio, Christian Carulli, Paolo Buselli, Sara Messina, Giuseppe Quattrone, Piergiorgio Spaggiari
Purpose  After total knee arthroplasty (TKA), pain and swelling, especially in older and less cooperative patients, can limit the retrieval of a good range of motion and muscle tone and consequently the achievement of an optimal function outcome. A high-tech knee pad made of metal fibers emitting infrared energy was used in a group of patients undergoing TKA to assess its efficacy in the postoperative period with respect to a group with a placebo. Methods  Twelve patients used knee pads after surgery for 3 weeks and were evaluated using visual analog scale (VAS), Knee Society Rating Score, Cincinnati Knee Rating Score, and painkillers at specific timings...
March 2017: Joints
https://www.readbyqxmd.com/read/29111163/professionalism-a-core-competency-but-what-does-it-mean-a-survey-of-surgery-residents
#5
Joshua C Dilday, Elizabeth A Miller, Kyle Schmitt, Brian Davis, Kurt G Davis
OBJECTIVE: Professionalism is 1 of the 6 core competencies of the Accreditation Council of Graduate Medical Education. Despite its obvious importance, it is poorly defined in the literature and an understanding of its meaning has not been evaluated on surgical trainees. The American College of Surgeons (ACS) has previously published tenets of surgical professionalism. However, surgery residents may not share similar views on professionalism as those of the ACS. DESIGN: Surgical residents of all levels at 2 surgery residencies located in the same city were interviewed regarding their personal definitions, thoughts, and experiences regarding professionalism during their training...
October 27, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/29109094/cyp3a4-gene-is-a-novel-biomarker-for-predicting-a-poor-prognosis-in-hepatocellular-carcinoma
#6
REVIEW
Ryo Ashida, Yukiyasu Okamura, Keiichi Ohshima, Yuko Kakuda, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Takashi Sugino, Kenichi Urakami, Masatoshi Kusuhara, Ken Yamaguchi
BACKGROUND/AIM: Project HOPE (High-tech Omics-based Patient Evaluation) began in 2014 using integrated gene expression profiling (GEP) of cancer tissues as well as diathesis of each patient who underwent operation at our Institution. The aim of this study was to identify novel genes displaying altered gene expression related to the survival and early recurrence after hepatectomy for hepatocellular carcinoma (HCC) using the results of integrated GEP analysis. MATERIALS AND METHODS: The present study included 92 patients...
November 2017: Cancer Genomics & Proteomics
https://www.readbyqxmd.com/read/29106827/high-tech-low-cost-the-growing-place-of-wii-in-rehabilitation
#7
EDITORIAL
Emmanuel Coudeyre
No abstract text is available yet for this article.
November 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29102347/relation-of-changes-in-body-fat-distribution-to-oxidative-stress
#8
Heval M Kelli, Frank E Corrigan, Robert E Heinl, Devinder S Dhindsa, Muhammad Hammadah, Ayman Samman-Tahhan, Pratik Sandesara, Wesley T O'Neal, Ibhar Al Mheid, Yi-An Ko, Viola Vaccarino, Thomas R Ziegler, Laurence S Sperling, Kenneth Brigham, Dean Jones, Greg S Martin, Arshed A Quyyumi
Android fat is a surrogate measure of visceral obesity in the truncal region. Both visceral adiposity and oxidative stress (OS) are linked to cardiometabolic risk factors and clinical cardiovascular disease. However, whether body fat distribution (android vs gynoid) is associated with OS remains unknown. We hypothesized that increased android fat will be associated with greater OS. Body fat distribution and markers of OS, including plasma levels of reduced (cysteine and glutathione) and oxidized (cystine and glutathione disulfide) aminothiols, were estimated in 711 volunteers (67% female, 23% black, mean age 48 ± 11) enrolled in the Emory Georgia Tech Predictive Health study...
September 20, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29092771/development-and-validation-of-a-new-pediatric-resuscitation-and-trauma-outcome-presto-model-using-the-u-s-national-trauma-data-bank
#9
Etienne St-Louis, David Bracco, James Hanley, Tarek Razek, Robert Baird
BACKGROUND: There is a need for a pediatric trauma outcomes benchmarking model that is adapted for Low-and-Middle-Income Countries (LMICs). We used the National-Trauma-Data-Bank (NTDB) and applied constraints specific to resource-poor environments to develop and validate an LMIC-specific pediatric trauma score. METHODS: We selected a sample of pediatric trauma patients aged 0-14years in the NTDB from 2007 to 2012. Primary outcome was in-hospital death. Logistic regression was used to create the Pediatric Resuscitation and Trauma Outcome (PRESTO) score, which includes only low-tech predictor variables - those easily obtainable at point-of-care...
October 12, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29091790/evaluating-firms-r-d-performance-using-best-worst-method
#10
Negin Salimi, Jafar Rezaei
Since research and development (R&D) is the most critical determinant of the productivity, growth and competitive advantage of firms, measuring R&D performance has become the core of attention of R&D managers, and an extensive body of literature has examined and identified different R&D measurements and determinants of R&D performance. However, measuring R&D performance and assigning the same level of importance to different R&D measures, which is the common approach in existing studies, can oversimplify the R&D measuring process, which may result in misinterpretation of the performance and consequently fallacy R&D strategies...
October 19, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/29091447/probing-pharmaceutical-mixtures-during-milling-the-potency-of-low-frequency-raman-spectroscopy-in-identifying-disorder
#11
Greg Walker, Philipp Römann, Bettina Poller, Korbinian Löbmann, Holger Grohganz, Jeremy S Rooney, Gregory S Huff, Geoffrey P S Smith, Thomas Rades, Keith C Gordon, Clare J Strachan, Sara J Fraser-Miller
This study uses a multimodal analytical approach to evaluate the rates of (co)amorphization of milled drug and excipient and the effectiveness of different analytical methods in detecting these changes. Indomethacin and tryptophan were the model substances, and the analytical methods included low-frequency Raman spectroscopy (785 nm excitation and capable of measuring both low- (10 to 250 cm(-1)) and midfrequency (450 to 1800 cm(-1)) regimes, and a 830 nm system (5 to 250 cm(-1))), conventional (200-3000 cm(-1)) Raman spectroscopy, Fourier transform infrared spectroscopy (FTIR), and X-ray powder diffraction (XRPD)...
November 16, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29077397/supercharged-precise-megametallodendrimers-via-a-single-step-quantitative-assembly-process
#12
Ting-Zheng Xie, Xiaolei Wu, Kevin J Endres, Zaihong Guo, Xiaocun Lu, Jingyi Li, Erendra Manandhar, James M Ludlow, Charles N Moorefield, Mary Jane Saunders, Chrys Wesdemiotis, George R Newkome
Synthesis of giant unimolecular dendrimers is challenging due, in part, to difficulties encountered at higher generations, in both convergent and divergent protocols because of the multistep construction/purification process. Herein, we report a hybrid synthetic procedure in which the core is constructed last. This quantitative assembly generated a metallodendrimer that is supercharged (120+), large (11.3 nm diameter), and its core was previously established. The series of complexes has been unequivocally characterized by NMR, ESI-IM-MS, and TEM techniques...
November 8, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29074807/wearable-tech-for-dogs
#13
(no author information available yet)
No abstract text is available yet for this article.
October 28, 2017: Veterinary Record
https://www.readbyqxmd.com/read/29072434/tech-trends-a-look-into-the-latest-dental-and-general-technology-on-the-market
#14
Hubert Chan, Blake Ellington
No abstract text is available yet for this article.
May 2017: Journal of the California Dental Association
https://www.readbyqxmd.com/read/29068627/tech-trends-a-look-into-the-latest-dental-and-general-technology-on-the-market
#15
Hubert Chan, Blake Ellington
No abstract text is available yet for this article.
April 2017: Journal of the California Dental Association
https://www.readbyqxmd.com/read/29064640/tech-trends-a-look-into-the-latest-dental-and-general-technology-on-the-market
#16
Hubert Chan, Blaine Wasylkiw
No abstract text is available yet for this article.
March 2017: Journal of the California Dental Association
https://www.readbyqxmd.com/read/29059995/recovery-of-forearm-occluded-trajectory-in-kinect-using-a-wrist-mounted-inertial-measurement-unit
#17
Prayook Jatesiktat, Wei Tech Ang
Kinect sensor is a successful device that lets 3D human motion capture be used in a general residential setting. This work aims to fulfill some missing capabilities in Kinect, which are forearm orientation estimation and forearm tracking in occlusion. By using a wrist-mounted Inertial Measurement Unit and Kinect's built-in skeleton tracking, we have developed a fusion procedure that improves the upper limb motion tracking without adding too many obtrusive devices to the user.
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059826/an-elderly-fall-detection-using-a-wrist-worn-accelerometer-and-barometer
#18
Prayook Jatesiktat, Wei Tech Ang
As the world population is growing toward an aging society, elderly fall becomes a serious problem. Automatic fall detection and alert systems could shorten their waiting time after a fall and mitigate its physical and mental negative consequences. This work proposes a method that integrates a 3-axis accelerometer and a barometer on a wrist-worn device for the fall detection task. The method focuses on the use of noisy signals from a barometer in both pre-processing steps and feature extractions. A use of free falling events to address the lack of training data in a learning process is also explored...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059547/forensic-dna-typing-from-teeth-using-demineralized-root-tips
#19
Heitor Simões Dutra Corrêa, Fabio Luis Miranda Pedro, Luiz Evaristo Ricci Volpato, Thiago Machado Pereira, Gilberto Siebert Filho, Álvaro Henrique Borges
Teeth are widely used samples in forensic human genetic identification due to their persistence and practical sampling and processing. Their processing, however, has changed very little in the last 20 years, usually including powdering or pulverization of the tooth. The objective of this study was to present demineralized root tips as DNA sources while, at the same time, not involving powdering the samples or expensive equipment for teeth processing. One to five teeth from each of 20 unidentified human bodies recovered from midwest Brazil were analyzed...
October 12, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29059083/current-opinions-in-office-based-rhinology
#20
Aykut A Unsal, Naomi Gregory, Kenneth Rosenstein
PURPOSE OF REVIEW: The care of rhinologic patients has undergone a remarkable transformation in recent years. With the advent of endoscopic sinus surgery and high-tech image-guided computer systems, the surgical care of patients with benign sinonasal disease has successfully transitioned from the main hospital operating room to the outpatient ambulatory surgical center. Currently, there is yet another movement underway, in an attempt to care for these patients in the office setting. RECENT FINDINGS: As the medical device sector continues to innovate at rapid speed, new technologies such as the radiofrequency ablator, microdebrider, balloon sinus dilator, and steroid-eluting stent have propelled the care of rhinologic patients into the clinic setting...
October 20, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
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