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gastroesophagical reflux disease

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https://www.readbyqxmd.com/read/29029355/over-sewing-of-staple-line-in-laparoscopic-sleeve-gastrectomy-initial-experience-of-a-comparative-study
#1
Giorgio Lisi, Roberto Rossini, Irene Gentile, Giacomo Ruffo
INTRODUCTION: The main drawback of laparoscopic sleeve gastrectomy (LSG) is the severity of postoperative complications. Staple line reinforcement (SLR) is strongly advocated. Recently, over-sewing has been proposed as a cost-effective and helpful method for reinforcing the staple line. The purpose of this study was to report our initial experience with LSG comparing over-sewing over the entire staple line with the upper-third staple line. MATERIALS AND METHODS: All obese patients seen at Negrar Sacro Cuore, Don Calabria Hospital were entered into our prospective database and were retrospectively evaluated...
October 12, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29025018/the-association-between-waterpipe-smoking-and-gastroesophageal-reflux-disease
#2
Arash Etemadi, Abdullah Gandomkar, Neal D Freedman, Mohsen Moghadami, Mohammad Reza Fattahi, Hossein Poustchi, Farhad Islami, Paolo Boffetta, Sanford M Dawsey, Christian C Abnet, Reza Malekzadeh
Background: Unlike cigarettes, there is little information about the association between other tobacco products and the risk of gastroesophageal reflux disease (GERD) and esophageal adenocarcinoma. Methods: We used the baseline data from the Pars Cohort Study conducted in southern Iran. In 2012, 9264 local residents between 40 and 75 years old were enrolled, with detailed information about lifestyle, including duration and frequency of tobacco use. GERD was defined based on questions assessing heartburn and regurgitation in the past 12 months, frequency and severity...
August 19, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29022245/prevalence-of-eosinophilic-esophagitis-in-patients-with-gastroesophageal-reflux-symptoms-a-cross-sectional-study-from-a-tertiary-care-hospital-in-north-india
#3
Bhaskarjyoti Baruah, Tarun Kumar, Prasenjit Das, Bhaskar Thakur, Vishnubatla Sreenivas, Vineet Ahuja, Siddhartha Datta Gupta, Govind K Makharia
BACKGROUND: Eosinophilic esophagitis (EoE) is being recognized increasingly all over the globe; Indian data is however sparse. We screened patients with symptoms of gastroesophageal reflux disease (GERD) for presence of EoE in them. METHODS: Consecutive patients with symptoms suggestive of GERD underwent gastroduodenoscopy and esophageal biopsies, obtained from both the upper esophagus (5 cm below the upper esophageal sphincter) and lower esophagus (5 cm above gastroesophageal junction), as well as from any other endoscopically visible abnormal mucosa...
October 12, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29021928/bravo%C3%A2-capsule-aspiration-a-rare-case-report
#4
Abdul Haseeb, Noman Lateef, Muhammad Bilal, Kumar Gaurav, Jason Prudom, Ali Musani
Bravo® capsule (BC) (Medtronic, Minneapolis, MN) endoscopy is a reliable, viable, and well-tolerated diagnostic modality for resistant gastroesophageal reflux disease (GERD). Common complications of the procedure include early dislodgment, poor transmission, and premature removal due to intractable pain, while aspiration of the capsule is exceedingly rare. This paper reports a case of BC aspiration in a 52-year-old female who presented after being ventilated when her oxygen saturation dropped. The initial chest radiograph revealed that the BC was in the right main bronchus; the site was further elaborated by flexible endoscopy and the capsule was found to be in the right lower lobe bronchus distal to the bronchus intermedius...
August 9, 2017: Curēus
https://www.readbyqxmd.com/read/29019565/sleeve-gastrectomy-and-fundoplication-as-a-single-procedure-in-patients-with-obesity-and-gastroesophageal-reflux
#5
Juan Pablo Lasnibat, Italo Braghetto, Luis Gutierrez, Felipe Sanchez
BACKGROUND: Bariatric surgery in Chile has seen an exponential increase in recent years, especially in sleeve gastrectomy. Its use is currently discussed in patients suffering from gastroesophageal reflux disease. Different options have been considered for the management of these patients but up to now laparoscopic Roux-en-Y gastric bypass seems to be the best option. Sleeve gastrectomy plus concomitant fundoplication or hiatal hernia repair also has been suggested in patients having reflux or small hiatal hernia...
July 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/29018932/analysis-of-growth-nutritional-status-and-hospital-visitation-scores-associated-with-reflux-after-nissen-fundoplication-in-neurologically-impaired-children-with-gastroesophageal-reflux
#6
Chaeyoun Oh, Joong Kee Youn, Ji-Won Han, Hyun-Young Kim, Sung-Eun Jung
BACKGROUND: Neurologically impaired children (NIC) often experience swallowing difficulties and gastroesophageal reflux disease (GERD). Although these conditions could place children in a state of poor nutritional status and prevent them from thriving, there is insufficient research evaluating growth and nutritional status following fundoplication in these patients. METHOD: This is a retrospective study of patients who were neurologically impaired and underwent Nissen fundoplication between April 2001 and March 2015...
October 10, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29018828/repurposing-lesogaberan-to-promote-human-islet-cell-survival-and-%C3%AE-cell-replication
#7
Jide Tian, Hoa Dang, Angela Hu, Willem Xu, Daniel L Kaufman
The activation of β-cell's A- and B-type gamma-aminobutyric acid receptors (GABAA-Rs and GABAB-Rs) can promote their survival and replication, and the activation of α-cell GABAA-Rs promotes their conversion into β-cells. However, GABA and the most clinically applicable GABA-R ligands may be suboptimal for the long-term treatment of diabetes due to their pharmacological properties or potential side-effects on the central nervous system (CNS). Lesogaberan (AZD3355) is a peripherally restricted high-affinity GABAB-R-specific agonist, originally developed for the treatment of gastroesophageal reflux disease (GERD) that appears to be safe for human use...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29016559/the-reflux-improvement-and-monitoring-trim-program-is-associated-with-symptom-improvement-and-weight-reduction-for-patients-with-obesity-and-gastroesophageal-reflux-disease
#8
Rena Yadlapati, John E Pandolfino, Olga Alexeeva, Dyanna L Gregory, Meredith R Craven, David Liebovitz, Abbey Lichten, Erin Seger, Moira Workman, Nora St Peter, Jenna Craft, Bethany Doerfler, Rajesh N Keswani
OBJECTIVES: Current healthcare systems do not effectively promote weight reduction in patients with obesity and gastroesophageal reflux disease (GERD). The Reflux Improvement and Monitoring (TRIM) program provides personalized, multidisciplinary, health education and monitoring over 6 months. In this study we aimed to (i) measure the effectiveness of TRIM on GERD symptoms, quality of life, and weight, and (ii) examine patient health beliefs related to TRIM. METHODS: This prospective mixed methods feasibility study was performed at a single center between September 2015 and February 2017, and included adult patients with GERD and a body mass index ≥30 kg/m(2)...
October 10, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28993985/gastroesophageal-reflux-after-sleeve-gastrectomy-a-prospective-mechanistic-study
#9
Muriel Coupaye, Caroline Gorbatchef, Daniela Calabrese, Ouidad Sami, Simon Msika, Benoit Coffin, Séverine Ledoux
BACKGROUND: Evolution of gastroesophageal reflux disease (GERD) after sleeve gastrectomy (SG) is controversial. Some authors report worsening or improvement of preoperative GERD, others the occurrence of de novo GERD between 5 and 69%. AIMS: The aims of this study are to evaluate the evolution of GERD after SG by ambulatory 24-h pH monitoring (APM) and to determine pre- and postoperative clinical and manometric factors associated with its evolution. METHODS: Between 2013 and 2015, 47 patients operated in our center performed APM before and 1 year (14...
October 9, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28992677/nationwide-multicenter-study-for-overlaps-of-common-functional-gastrointestinal-disorders-in-korean-patients-with-constipation
#10
Kyung Sik Park, Sam Ryong Jee, Bong Eun Lee, Kyoung Sup Hong, Jeong Eun Shin, Soo-Young Na, Joong Goo Kwon, Suck Chei Choi, Yong Sung Kim, Hyun Seok Lee, Tae Hee Lee, Kyeong Ok Kim, Jongkyoung Choi, Hee Seok Moon, Yeon Soo Kim, Moo In Park, Soo Jung Park, Seon-Young Park, Sung Noh Hong
Background/Aims: In spite of increased concerns about the overlaps among the various functional gastrointestinal disorders (FGIDs), studies for the overlap between constipation and other common FGIDs are rare. Therefore, we investigated the patterns of overlaps between constipation and other common FGIDs. Methods: This study was designed as a prospective nationwide multi-center questionnaire study using Rome III questionnaires for functional dyspepsia (FD), irritable bowel syndrome (IBS), and functional constipation (FC), as well as various questionnaires about patients' information, degree of symptoms, and quality of life...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992675/relationship-between-salivary-pepsin-concentration-and-esophageal-mucosal-integrity-in-patients-with-gastroesophageal-reflux-disease
#11
Yu-Wen Li, Daniel Sifrim, Chenxi Xie, Minhu Chen, Ying-Lian Xiao
Background/Aims: Increased salivary pepsin could indicate an increase in gastro-esophageal reflux, however, previous studies failed to demonstrate a correlation between salivary pepsin concentrations and 24-hour esophageal acid exposure. This study aims to detect the salivary pepsin and to evaluate the relationship between salivary pepsin concentrations and intercellular spaces (IS) in different gastroesophageal reflux disease phenotypes in patients. Methods: A total of 45 patients and 11 healthy volunteers were included in this study...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28986024/cystic-fibrosis-and-gastroesophageal-reflux-disease
#12
Asim Maqbool, Ans Pauwels
Gastroesophageal reflux is common in children and adults with cystic fibrosis (CF). Pathological gastroesophageal reflux disease (GERD) is also frequent in patients of all ages with CF. This article reviews the pathophysiology, diagnostic work-up, management options, complications, and future directions in the evaluation and management of GERD - unique to and pertinent for - patients with CF in particular.
September 25, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28986002/management-of-gastroesophageal-reflux-disease-and-hiatal-hernia-post-sleeve-gastrectomy-cardiopexy-with-ligamentum-teres
#13
Salman Al-Sabah, Shehab Akrouf, Mohannad Alhaddad, Jonathon D Vaz
No abstract text is available yet for this article.
September 1, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28982917/gastric-spindle-cell-neuroendocrine-tumor-mimicking-gastrointestinal-stromal-tumor-unique-morphology-and-diagnostic-pitfall
#14
Alexandria A Lee, Nishant Poddar, Muhammad B Hammami, Jula Veerapong, Dengfeng Cao, Jin-Ping Lai
Gastric neuroendocrine tumors (GNETs) with spindle cell morphology are extremely rare. We present a case of a 49-year-old female patient with a history of systemic lupus erythematosus, Sjogren's syndrome, and gastroesophageal reflux disease. She was initially thought to have a spindle cell gastrointestinal stromal tumor per histological studies of the fundic polypectomy samples. Immunohistochemically, the tumor cells were negative for CD117, and CD34, but positive for chromogranin, synaptophysin, and CD56 with a 6% Ki-67 index, consistent with a spindle cell-type well differentiated neuroendocrine tumor, World Health Organization (WHO) Grade 2...
October 2017: Anticancer Research
https://www.readbyqxmd.com/read/28981359/dendriform-pulmonary-ossification-in-the-absence-of-usual-interstitial-pneumonia-ct-features-and-possible-association-with-recurrent-acid-aspiration
#15
James F Gruden, Daniel B Green, Alan C Legasto, Eric A Jensen, Prasad M Panse
OBJECTIVE: Dendriform pulmonary ossification (DPO) is a rare lung disease in which mature bone is present in the peripheral interstitium of the lung. It typically occurs in patients with usual interstitial pneumonia (UIP). We assessed patients with CT findings of DPO without UIP to determine possible causative factors and to assess the clinical and CT course. We hypothesized that DPO without UIP would be a unique entity. MATERIALS AND METHODS: We retrospectively reviewed CT reports for the word "ossification...
October 5, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28980899/oesophageal-disease-in-systemic-sclerosis-does-heritability-play-a-role
#16
Tracy Frech, Latifa Fakoya, Andrew J Gawron, Jathine Wong, Mary Beth Scholand, Allen Sawitzke, Kathryn Peterson
OBJECTIVES: In systemic sclerosis (SSc) the most common gastrointestinal tract (GIT) complaint is gastroesophageal reflux disease (GERD), which may contribute to oesophagitis, stricture, Barrett's oesophagus, and oesophageal adenocarcinoma. We used a genealogical resource the Utah Population Database (UPDB) to analyse SSc pedigrees for hereditability of oesophageal disease. METHODS: SSc, GERD, oesophagitis, stricture, Barrett's, and oesophageal adenocarcinoma were defined by ICD Ninth and Tenth Revision codes...
October 2, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28980592/-the-prevalence-of-the-fungal-flora-in-association-with-chronic-inflammatory-pathology-of-the-larynx
#17
V Ya Kunel'skaya, S G Romanenko, G B Shadrin, D I Krasnikova
The present article was designed to analyze the prevalence and clinical features of laryngomycosis associated with chronic inflammatory diseases of the larynx. We examined 430 patients suffering from chronic pharyngitis and found the fungal flora in 100 (23.2%) of them. Diagnostics of the fungal infection was performed by the microscopic study of the stained preparations (including the Gram method, Romanovskiy-Giemsa and fluorescent microscopy). The sowing on elective nutrient media was used. The study revealed the presence of yeast fungi (Candida) in 98 patients (98%) and mold fungi (Aspergillus) in the remaining two (2%)...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28979613/-upper-gastrointestinal-ugi-endoscopy-in-louga-senegal-patients-profile-and-difficulties-encountered
#18
Georges Antoine Bazolo Ba Ngouala, Loubna Bourgi, Joao Arm Indo Da Veiga, Arona Sakho
INTRODUCTION: This study aimed to determine the epidemiological, clinical and endoscopic profile of patients referred for upper gastrointestinal (UGI) endoscopy to the Clinique Magou in Louga and to analyze the difficulties encountered. METHODS: We conducted a retrospective and descriptive study by analysing the reports of 248 gastrointestinal endoscopies performed between 1(st) January and 31(st) December 2014. RESULTS: The average age was 39...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28978876/future-perspective-of-research-and-clinical-practice-in-gastroesophageal-reflux-disease
#19
Yoshikazu Kinoshita, Shunji Ishihara, Norihisa Ishimura
No abstract text is available yet for this article.
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/28978214/strategies-to-manage-costs-in-idiopathic-pulmonary-fibrosis
#20
Gary M Owens
Idiopathic pulmonary fibrosis (IPF) is a diagnostically challenging disease. Clinicians are faced with the need to exclude alternative diagnoses, limited treatment and management guidelines, and few treatment options. Patients with IPF have significantly increased healthcare usage compared with similar patients without the disease. Medicare estimates for this disease are as high as $3 billion, not including cost of treatment. The disease, characterized by worsening dyspnea, declining lung function, nonspecific respiratory symptoms, and a varied clinical course randomly punctuated by episodes of acute exacerbations, is also accompanied by a host of comorbid conditions that contribute significantly to increased healthcare usage and cost...
July 2017: American Journal of Managed Care
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