keyword
MENU ▼
Read by QxMD icon Read
search

Vae

keyword
https://www.readbyqxmd.com/read/29025410/association-between-traditional-cardiovascular-risk-factors-and-mortality-in-the-oldest-old-untangling-the-role-of-frailty
#1
Bert Vaes, David Depoortere, Gijs Van Pottelbergh, Catharina Matheï, Joana Neto, Jan Degryse
BACKGROUND: To date, there is no consensus regarding cardiovascular risk management in the very old. Studies have shown that the relationship between traditional cardiovascular risk factors and mortality is null or even inverted within this age group. This relationship could be modified by the presence of frailty. This study was performed to examine the effect of frailty on the association between cardiovascular risk factors and mortality in the oldest old. METHODS: The BELFRAIL study is a prospective, observational, population-based cohort study of 567 subjects aged 80 years and older...
October 12, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29016831/estimating-the-prevalence-of-diabetes-mellitus-and-thyroid-disorders-using-medication-data-in-flanders-belgium
#2
Bert Vaes, Catherine Ruelens, Samuel Saikali, Alexander Smets, Séverine Henrard, Francoise Renard, Marjan van den Akker, Gijs Van Pottelbergh, Geert Goderis, Johan Van der Heyden
Background: Various methods exist to estimate disease prevalences. The aim of this study was to determine whether dispensed, self-reported and prescribed medication data could be used to estimate the prevalence of diabetes mellitus and thyroid disorders. Second, these pharmaco-epidemiological estimates were compared with prevalences based on self-reported diagnoses and doctor-registered diagnoses. Methods: Data on medication for diabetes and thyroid disorders were obtained from three different sources in Flanders (Belgium) for 2008: a purely administrative database containing data on dispensed medication, the Belgian National Health Interview Survey for self-reported medication and diagnoses, and a patient record database for prescribed medication and doctor-registered diagnoses...
July 16, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28978239/endothelial-function-in-patients-with-chronic-obstructive-pulmonary-disease-a-systematic-review-of-studies-using-flow-mediated-dilatation
#3
Anouk W Vaes, Martijn A Spruit, Jan Theunis, Nandu Goswami, Lowie E Vanfleteren, Frits M E Franssen, Emiel F M Wouters, Patrick De Boever
BACKGROUND: Cardiovascular disease is an important cause of morbidity and mortality in chronic obstructive pulmonary disease (COPD). Endothelial function may be involved in the pathogenesis of cardiovascular disease. In contrast to the attention given to pulmonary endothelial dysfunction, little is known about peripheral vascular changes in COPD. Therefore, we reviewed the literature on peripheral endothelial function in COPD. METHODS: Databases were screened for studies using ultrasound-based flow-mediated dilation (FMD), the reference method for assessing peripheral endothelial function, in stable COPD patients...
October 5, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28832263/vasorelaxant-properties-of-vernonia-amygdalina-ethanol-extract-and-its-possible-mechanism
#4
Yung Sing Ch'ng, Yean Chun Loh, Chu Shan Tan, Mariam Ahmad, Mohd Zaini Asmawi, Wan Maznah Wan Omar, Mun Fei Yam
CONTEXT: Vernonia amygdalina Del. (VA) (Asteraceae) is commonly used to treat hypertension in Malaysia. OBJECTIVE: This study investigates the vasorelaxant mechanism of VA ethanol extract (VAE) and analyzes its tri-step FTIR spectroscopy fingerprint. MATERIALS AND METHODS: Dried VA leaves were extracted with ethanol through maceration and concentrated using rotary evaporator before freeze-dried. The vasorelaxant activity and the underlying mechanisms of VAE using the cumulative concentration (0...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28802790/vascular-air-embolism-a-silent-hazard-to-patient-safety
#5
REVIEW
Sorin J Brull, Richard C Prielipp
PURPOSE: To narratively review published information on prevention, detection, pathophysiology, and appropriate treatment of vascular air embolism (VAE). MATERIALS AND METHODS: MEDLINE, SCOPUS, Cochrane Central Register and Google Scholar databases were searched for data published through October 2016. The Manufacturer and User Facility Device Experience (MAUDE) database was queried for "air embolism" reports (years 2011-2016). RESULTS: VAE may be introduced through disruption in the integrity of the venous circulation that occurs during insertion, maintenance, or removal of intravenous or central venous catheters...
August 7, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28794685/a-posteriori-accuracy-estimation-of-ultrasonic-vector-flow-mapping-vfm
#6
Tomohiko Tanaka, Rei Asami, Ken-Ichi Kawabata, Kunio Hashiba, Takashi Okada, Tomohide Nishiyama
ABSTRACT: A novel method, called a posteriori "VFM accuracy estimation" (VAE), for resolving an intrinsic VFM problem is proposed. The problem is that VFM uncertainty can easily vary according to blood flows through an echocardiographic imaged plane (i.e., "through-plane" flows), and it is unknown. Knowing the VFM uncertainty for each patient will make it possible to refine the quality of VFM-based diagnosis. In the present study, VAE was derived on the basis of an error-propagation analysis and a statistical analysis...
2017: Journal of Visualization
https://www.readbyqxmd.com/read/28774199/physical-activity-patterns-and-clusters-in-1001-patients-with-copd
#7
Rafael Mesquita, Gabriele Spina, Fabio Pitta, David Donaire-Gonzalez, Brenda M Deering, Mehul S Patel, Katy E Mitchell, Jennifer Alison, Arnoldus Jr van Gestel, Stefanie Zogg, Philippe Gagnon, Beatriz Abascal-Bolado, Barbara Vagaggini, Judith Garcia-Aymerich, Sue C Jenkins, Elisabeth Apm Romme, Samantha Sc Kon, Paul S Albert, Benjamin Waschki, Dinesh Shrikrishna, Sally J Singh, Nicholas S Hopkinson, David Miedinger, Roberto P Benzo, François Maltais, Pierluigi Paggiaro, Zoe J McKeough, Michael I Polkey, Kylie Hill, William D-C Man, Christian F Clarenbach, Nidia A Hernandes, Daniela Savi, Sally Wootton, Karina C Furlanetto, Li W Cindy Ng, Anouk W Vaes, Christine Jenkins, Peter R Eastwood, Diana Jarreta, Anne Kirsten, Dina Brooks, David R Hillman, Thaís Sant'Anna, Kenneth Meijer, Selina Dürr, Erica Pa Rutten, Malcolm Kohler, Vanessa S Probst, Ruth Tal-Singer, Esther Garcia Gil, Albertus C den Brinker, Jörg D Leuppi, Peter Ma Calverley, Frank Wjm Smeenk, Richard W Costello, Marco Gramm, Roger Goldstein, Miriam Tj Groenen, Helgo Magnussen, Emiel Fm Wouters, Richard L ZuWallack, Oliver Amft, Henrik Watz, Martijn A Spruit
We described physical activity measures and hourly patterns in patients with chronic obstructive pulmonary disease (COPD) after stratification for generic and COPD-specific characteristics and, based on multiple physical activity measures, we identified clusters of patients. In total, 1001 patients with COPD (65% men; age, 67 years; forced expiratory volume in the first second [FEV1], 49% predicted) were studied cross-sectionally. Demographics, anthropometrics, lung function and clinical data were assessed...
August 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28720671/the-impact-of-ventilator-associated-events-in-critically-ill-subjects-with-prolonged-mechanical-ventilation
#8
Hidetsugu Kobayashi, Shigehiko Uchino, Masanori Takinami, Shoichi Uezono
BACKGROUND: The Centers for Disease Control and Prevention recently released a surveillance definition for respiratory complications in ventilated patients, ventilator-associated events (VAE), to replace ventilator-associated pneumonia (VAP). VAE consists of ventilator-associated conditions (VAC), infection-related ventilator-associated complications (IVAC), and possible VAP. A duration of mechanical ventilation of at least 4 d is required to diagnose VAE. However, the observed duration of mechanical ventilation was < 4 d in many previous studies...
July 18, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28719632/viscum-album-neutralizes-tumor-induced-immunosuppression-in-a-human-in-vitro-cell-model
#9
Carmen Steinborn, Amy Marisa Klemd, Ann-Sophie Sanchez-Campillo, Sophie Rieger, Marieke Scheffen, Barbara Sauer, Manuel Garcia-Käufer, Konrad Urech, Marie Follo, Annekathrin Ücker, Gunver Sophia Kienle, Roman Huber, Carsten Gründemann
Tumor cells have the capacity to secrete immunosuppressive substances in order to diminish dendritic cell (DC) activity and thereby escape from immune responses. The impact of mistletoe (Viscum album) extracts (VAE), which are frequently used as an additive anti-cancer therapy to stimulate the immune response, is still unknown. Using a human cellular system, the impact of two different VAE (VAEA + VAEI) on the maturation of human dendritic cells and on T cell function has been investigated using flow cytometry, automated fluorescence microscopy and cytokine bead array assays...
2017: PloS One
https://www.readbyqxmd.com/read/28703000/drugan-an-advanced-generative-adversarial-autoencoder-model-for-de-novo-generation-of-new-molecules-with-desired-molecular-properties-in-silico
#10
Artur Kadurin, Sergey Nikolenko, Kuzma Khrabrov, Alex Aliper, Alex Zhavoronkov
Deep generative adversarial networks (GANs) are the emerging technology in drug discovery and biomarker development. In our recent work, we demonstrated a proof-of-concept of implementing deep generative adversarial autoencoder (AAE) to identify new molecular fingerprints with predefined anticancer properties. Another popular generative model is the variational autoencoder (VAE), which is based on deep neural architectures. In this work, we developed an advanced AAE model for molecular feature extraction problems, and demonstrated its advantages compared to VAE in terms of (a) adjustability in generating molecular fingerprints; (b) capacity of processing very large molecular data sets; and (c) efficiency in unsupervised pretraining for regression model...
August 4, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28681902/integration-of-scheimpflug-based-corneal-tomography-and-biomechanical-assessments-for-enhancing-ectasia-detection
#11
Renato Ambrósio, Bernardo T Lopes, Fernando Faria-Correia, Marcella Q Salomão, Jens Bühren, Cynthia J Roberts, Ahmed Elsheikh, Riccardo Vinciguerra, Paolo Vinciguerra
PURPOSE: To present the Tomographic and Biomechanical Index (TBI), which combines Scheimpflugbased corneal tomography and biomechanics for enhancing ectasia detection. METHODS: Patients from different continents were retrospectively studied. The normal group included 1 eye randomly selected from 480 patients with normal corneas and the keratoconus group included 1 eye randomly selected from 204 patients with keratoconus. There were two groups: 72 ectatic eyes with no surgery from 94 patients with very asymmetric ectasia (VAE-E group) and the fellow eyes of these patients with normal topography (VAE-NT group)...
July 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28653254/prognostic-value-of-short-term-decline-of-forced-expiratory-volume-in-1%C3%A2-s-over-height-cubed-fev1-ht-3-in-a-cohort-of-adults-aged-80-and-over
#12
Eralda Hegendörfer, Bert Vaes, Catharina Matheï, Gijs Van Pottelbergh, Jean-Marie Degryse
BACKGROUND: Forced expiratory volume in 1 s over height cubed (FEV1/Ht(3)) is an FEV1 expression that uses no reference values and is independently associated with adverse outcomes in older adults. No studies have reported on the prognostic value of its decline over time in adults aged 80 and over. AIM: To investigate the prognostic value of FEV1/Ht(3) decline for adverse outcomes in a cohort of adults aged 80 and over. METHODS: 328 community-dwelling adults aged 80 and over of the BELFRAIL prospective cohort had two valid FEV1 measurements as part of their comprehensive geriatric assessment at baseline and follow-up (after 1...
June 26, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28648964/factors-associated-with-prolonged-inaction-in-the-hypoglycaemic-treatment-in-people-with-non-insulin-dependent-type-2-diabetes-and-elevated-glycated-haemoglobin-a-registry-based-cohort-study
#13
Geert Goderis, Bert Vaes, Marjan Van den Akker, Steven Elli, Chantal Mathieu, Frank Buntinx, Séverine Henrard
AIMS: To assess factors associated with Prolonged Inaction (PI) in insulin-naïve patients with Type 2 Diabetes Mellitus (T2DM). PI was defined as the absence of treatment initiation or intensification for ≥12 months despite HbA1c >7% (53mmol/mol). METHODS: A retrospective cohort study was conducted based on data from Intego, a Flemish General Practice registry. The study period ranged from January 1, 2006 to December 31, 2013. Patients with insulin therapy before the start of the study period were excluded from the analysis...
June 22, 2017: Primary Care Diabetes
https://www.readbyqxmd.com/read/28646723/vacuum-assisted-complete-excision-of-solid-intraductal-intracystic-masses-and-complex-cysts-is-follow-up-necessary
#14
Vanessa Quinn-Laurin, Jean-Charles Hogue, Sylvie Pinault, Nathalie Duchesne
INTRODUCTION: Management of complex cysts and benign intraductal/intracystic masses is controversial. The aim of this study was to determine if the complete removal of the complex cyst lesions with ultrasound-guided vacuum-assisted excision (US-VAE) is sufficient for their safe management when the histological diagnosis obtained at biopsy is benign. SUBJECTS AND METHODS: This is a single institution retrospective study performed on patients who underwent breast biopsy between April 2007 and September 2013...
June 21, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28633384/correlates-of-dyspnoea-and-its-association-with-adverse-outcomes-in-a-cohort-of-adults-aged-80-and-over
#15
Eralda Hegendörfer, Bert Vaes, Catharina Matheï, Gijs Van Pottelbergh, Jean-Marie Degryse
Background: adults aged 80 and over, a fast growing age-group, with increased co-morbidity and frailty have not been the focus of previous research on dyspnoea. We investigate the correlates of dyspnoea and its association with adverse outcomes in a cohort of adults aged 80 and over. Methods: about 565 community-dwelling adults aged 80 and over of the BELFRAIL prospective cohort had assessment of Medical Research Council dyspnoea scale (MRC), forced expiratory volume in 1 s (FEV1), N-terminal pro-brain natriuretic peptide (NT-proBNP), physical performance tests, grip strength, 15 items geriatric depression scale, activities of daily living (ADL), body mass index (BMI) and demographics data...
June 14, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28617683/estimation-of-population-based-cancer-specific-potential-years-of-life-lost-in-belgium
#16
Geert Silversmit, Evelien Vaes, Liesbet van Eycken
The potential years of life lost (PYLL) observed in a cohort of cancer patients cannot be fully assigned to the cancer as both cancer-related and non-cancer-related deaths contribute. A method is presented to decompose the observed all-cause PYLL into cancer mortality and population background mortality fractions when cause of death information is not available. Furthermore, the association of cancer-specific PYLL with cancer-specific mortality and mean age at diagnosis is explored and the impact of the follow-up window length is examined...
September 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28614140/a-comparison-of-clinical-characteristics-and-outcomes-of-ventilator-associated-pneumonias-among-burn-patients-by-diagnostic-criteria-set
#17
Duraid Younan, Russell Griffin, Thomas Swain, Eric Schinnerer, Jean-Francois Pittet, Bernard Camins
OBJECTIVES: The National Healthcare Safety Network (NHSN) replaced its old definition for ventilator associated pneumonia (VAP) with ventilator associated events (VAEs) in 2013. Little data is available comparing the two definitions in burn patients. METHODS: Data from 2011-2014 were collected on burn patients mechanically ventilated for at least two days. VAP was determined using two methods: (1) pneumonia as defined by the previous more clinical CDC (NHSN) definition captured in the burn registry; (2) pneumonia as defined by the recent CDC (NHSN) standard of Ventilator-Associated Events where patients meeting the criteria for possible VAP (PVAP) were considered having a pneumonia...
June 13, 2017: Shock
https://www.readbyqxmd.com/read/28581150/objectification-seeing-and-treating-people-as-things
#18
EDITORIAL
Steve Loughnan, Jeroen Vaes
No abstract text is available yet for this article.
June 2017: British Journal of Social Psychology
https://www.readbyqxmd.com/read/28578679/effectiveness-of-additional-trunk-exercises-on-gait-performance-study-protocol-for-a-randomized-controlled-trial
#19
Tamaya Van Criekinge, Wim Saeys, Ann Hallemans, Luc Vereeck, Willem De Hertogh, Patricia Van de Walle, Nathalie Vaes, Christophe Lafosse, Steven Truijen
BACKGROUND: Evidence is lacking concerning the effect of additional trunk rehabilitation on gait performance. Investigating gait performance by both clinical and biomechanical outcome measures might lead to new scientific insights into the importance of the trunk during gait rehabilitation in people suffering from stroke. This protocol was written according to the SPIRIT 2013 Statement. METHODS AND DESIGN: An assessor-blinded randomized controlled trial will be conducted in patients with impaired trunk control after stroke...
June 2, 2017: Trials
https://www.readbyqxmd.com/read/28561600/current-pneumonia-surveillance-methodology-similar-underestimation-in-trauma-and-surgical-patients-in-the-intensive-care-unit
#20
Brenda M Zosa, Joseph F Golob, Kristen J Conrad-Schnetz, David Schechtman, Laura A Kreiner, Jeffrey A Claridge
BACKGROUND: In 2013, the Centers for Disease Control and Prevention (CDC) developed new surveillance definitions for ventilator-associated events (VAE), leading to concerns that hospitals may be underreporting the true incidence of ventilator-associated pneumonias (VAPs). We sought to compare rates of clinically diagnosed VAP with CDC defined possible VAPs (PVAPs) in patients with a VAE in the surgical/trauma intensive care unit (STICU). HYPOTHESIS: Significant difference exists between rates of clinical VAP and PVAP in patients with at least one VAE...
July 2017: Surgical Infections
keyword
keyword
9871
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"