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https://www.readbyqxmd.com/read/28219878/features-of-a-mobile-support-app-for-patients-with-chronic-obstructive-pulmonary-disease-literature-review-and-current-applications
#1
Drishty D Sobnath, Nada Philip, Reem Kayyali, Shereen Nabhani-Gebara, Barbara Pierscionek, Anouk W Vaes, Martijn A Spruit, Evangelos Kaimakamis
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a serious long-term lung disease in which the airflow from the lungs is progressively reduced. By 2030, COPD will become the third cause of mortality and seventh cause of morbidity worldwide. With advances in technology and mobile communications, significant progress in the mobile health (mHealth) sector has been recently observed. Mobile phones with app capabilities (smartphones) are now considered as potential media for the self-management of certain types of diseases such as asthma, cancer, COPD, or cardiovascular diseases...
February 20, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28215200/health-team-for-the-elderly-a-feasibility-study-for-preventive-home-visits
#2
Berit Seiger Cronfalk, Astrid Fjell, Nina Carstens, Lars Malvin Kvinge Rosseland, Arvid Rongve, Dag-Helge Rönnevik, Åke Seiger, Knut Skaug, Karen Johanne Ugland Vae, Marianne Hauge Wennersberg, Anne-Marie Boström
: The aim was to describe the development, utilization and feasibility of a model of preventive home visits, in an urban and a rural municipality in Norway. BACKGROUND: Older people >65 years will rise significantly in coming years. Increased age is associated with risk of disability, illness and need for public health services. Preventive home visits is assumed to help older people to maintain their functional level longer, delaying disease and thus delaying the need for health care...
February 20, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/28198021/internalizing-objectification-objectified-individuals-see-themselves-as-less-warm-competent-moral-and-human
#3
Steve Loughnan, Cristina Baldissarri, Federica Spaccatini, Laura Elder
People objectify others by viewing them as less warm, competent, moral, and human (Heflick & Goldenberg, 2009, J. Exp. Soc. Psychol., 45, 598; Vaes, Paladino, & Puvia, 2011, Eur. J. Soc. Psychol., 41, 774). In two studies, we examined whether the objectified share this view of themselves, internalizing their objectification. In Study 1 (N = 114), we examined sexual objectification, and in Study 2 (N = 62), we examined workplace objectification. Consistent across both studies, we found that objectification resulted in participants seeing themselves as less warm, competent, moral (Study 2 only), and lacking in human nature and human uniqueness...
February 15, 2017: British Journal of Social Psychology
https://www.readbyqxmd.com/read/28185740/vaccine-adverse-events-in-a-safety-net-healthcare-system-and-a-managed-care-organization
#4
Komal J Narwaney, Kristin Breslin, Colleen A Ross, Jo Ann Shoup, Kris F Wain, Eric S Weintraub, Michael M McNeil, Simon J Hambidge
BACKGROUND: The Institute of Medicine, in a 2013 report, recommended that the Vaccine Safety Datalink (VSD) expand collaborations to include more diversity in the study population. Kaiser Permanente Colorado (KPCO), an established VSD site, partnered with Denver Health (DH), an integrated safety net healthcare system, to demonstrate the feasibility of integrating DH data within the VSD. Prior to incorporating the data, we examined the identification of specific vaccine associated adverse events (VAEs) in these two distinct healthcare systems...
February 6, 2017: Vaccine
https://www.readbyqxmd.com/read/28157839/establishment-of-a-method-for-evaluating-endothelial-cell-injury-by-tnf-%C3%AE-in-vitro-for-clarifying-the-pathophysiology-of-virus-associated-acute-encephalopathy
#5
Kyohei Miyazaki, Koichi Hashimoto, Masatoki Sato, Masahiro Watanabe, Naoki Tomikawa, Shuto Kanno, Yukihiko Kawasaki, Nobuo Momoi, Mitsuaki Hosoya
BACKGROUND: Virus-associated acute encephalopathy (VAE) is a severe central nervous system complication caused by common viral infections in children. The pathophysiology of VAE is thought to be endothelial injury. This study was designed to establish an in vitro VAE model for evaluating endothelial injury caused by the proinflammatory cytokine TNF-α. METHODS: Transwell-grown human umbilical vein endothelial cells (HUVECs) monolayers were incubated with serially diluted TNF-α...
February 3, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28155137/successful-use-of-14-c-paracetamol-microdosing-to-elucidate-developmental-changes-in-drug-metabolism
#6
Miriam G Mooij, Esther van Duijn, Catherijne A J Knibbe, Karel Allegaert, Albert D Windhorst, Joost van Rosmalen, N Harry Hendrikse, Dick Tibboel, Wouter H J Vaes, Saskia N de Wildt
BACKGROUND: We previously showed the practical and ethical feasibility of using [(14)C]-microdosing for pharmacokinetic studies in children. We now aimed to show that this approach can be used to elucidate developmental changes in drug metabolism, more specifically, glucuronidation and sulfation, using [(14)C]paracetamol (AAP). METHODS: Infants admitted to the intensive care unit received a single oral [(14)C]AAP microdose while receiving intravenous therapeutic AAP every 6 h...
February 2, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28130975/nursing-students-perceptions-of-using-the-clinical-education-assessment-tool-assce-and-their-overall-perceptions-of-the-clinical-learning-environment-a-cross-sectional-correlational-study
#7
Maria Engström, Anna Löfmark, Karen Johanne Ugland Vae, Gunilla Mårtensson
BACKGROUND: Clinical education is a vital part of nursing students' learning; the importance of assessment tools and feedback in stimulating student learning has been stressed, but this needs to be studied in more detail. OBJECTIVES: To examine relationships between nursing students' perceptions of using an Assessment tool in Clinical Education (AssCE) during their mid-course discussion and final assessment, the content discussed during these meetings between the student, preceptor and nurse teacher and the students' overall perception of the clinical learning environment...
January 22, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28049197/venous-air-embolism-during-hysteroscopic-myomectomy-an-analysis-of-7-cases
#8
Cédric Van Dijck, Steffen Rex, Jasper Verguts, Dirk Timmerman, Marc Van de Velde, An Teunkens
Venous air embolism (VAE) is a rare but potentially fatal complication of hysteroscopic myomectomy. The symptoms of VAE range from mild and clinically insignificant to complete cardiovascular collapse during surgery. Anesthesiologists and surgeons should be aware of the clinical characteristics and predisposing factors of this possible adverse event. This report analyzes 7 cases of VAE, which occurred at the University Hospitals Leuven, in patients undergoing hysteroscopic myomectomy from April 2009 to April 2011...
January 4, 2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/28045549/curcumin-and-viscum-album-extract-decrease-proliferation-and-cell-viability-of-soft-tissue-sarcoma-cells-an-in-vitro-analysis-of-eight-cell-lines-using-real-time-monitoring-and-colorimetric-assays
#9
K Harati, B Behr, A Daigeler, T Hirsch, F Jacobsen, M Renner, A Harati, C Wallner, M Lehnhardt, M Becerikli
BACKGROUND: The cytostatic effects of the polyphenol curcumin and Viscum album extract (VAE) were assessed in soft-tissue sarcoma (STS) cells. METHODS: Eight human STS cell lines were used: fibrosarcoma (HT1080), liposarcoma (SW872, T778, MLS-402), synovial sarcoma (SW982, SYO1, 1273), and malignant fibrous histiocytoma (U2197). Primary human fibroblasts served as control cells. Cell proliferation, viability, and cell index (CI) were analyzed by BrdU assay, MTT assay, and real-time cell analysis (RTCA)...
January 3, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28003033/short-physical-performance-battery-and-all-cause-mortality-systematic-review-and-meta-analysis
#10
Rita Pavasini, Jack Guralnik, Justin C Brown, Mauro di Bari, Matteo Cesari, Francesco Landi, Bert Vaes, Delphine Legrand, Joe Verghese, Cuiling Wang, Sari Stenholm, Luigi Ferrucci, Jennifer C Lai, Anna Arnau Bartes, Joan Espaulella, Montserrat Ferrer, Jae-Young Lim, Kristine E Ensrud, Peggy Cawthon, Anna Turusheva, Elena Frolova, Yves Rolland, Valerie Lauwers, Andrea Corsonello, Gregory D Kirk, Roberto Ferrari, Stefano Volpato, Gianluca Campo
BACKGROUND: The Short Physical Performance Battery (SPPB) is a well-established tool to assess lower extremity physical performance status. Its predictive ability for all-cause mortality has been sparsely reported, but with conflicting results in different subsets of participants. The aim of this study was to perform a meta-analysis investigating the relationship between SPPB score and all-cause mortality. METHODS: Articles were searched in MEDLINE, the Cochrane Library, Google Scholar, and BioMed Central between July and September 2015 and updated in January 2016...
December 22, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27995743/anticholinergic-exposure-in-a-cohort-of-adults-aged-80-years-and-over-associations-of-the-marante-scale-with-mortality-and-hospitalisation
#11
Maarten Wauters, Therese Klamer, Monique Elseviers, Bert Vaes, Olivia Dalleur, Jan Degryse, Carlos Durán, Thierry Christiaens, Majda Azermai, Robert Vander Stichele
Anticholinergics are frequently prescribed for older adults and can lead to adverse drug events. The novel MARANTE (Muscarinic Acetylcholinergic Receptor ANTagonist Exposure) scale measures the anticholinergic exposure by incorporating potency and dosages of each medication into its calculations. The aims were to assess prevalence and intensity of the anticholinergic exposure in a longitudinal cohort study of community-dwelling patients aged 80 years and over (n=503) and to study the impact on mortality and hospitalisation...
December 20, 2016: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/27982770/the-semisitting-position-analysis-of-the-risks-and-surgical-outcomes-in-a-contemporary-series-of-425-adult-patients-undergoing-cranial-surgery
#12
Andrea Saladino, Massimo Lamperti, Antonella Mangraviti, Federico G Legnani, Francesco U Prada, Cecilia Casali, Luigi Caputi, Paola Borrelli, Francesco DiMeco
OBJECTIVE The objective of this study was to analyze the incidence of the primary complications related to positioning or surgery and their impact on neurological outcome in a consecutive series of patients undergoing elective surgery in the semisitting position. METHODS The authors prospectively collected and retrospectively analyzed data from adult patients undergoing elective surgery in the semisitting position for a cranial disease. Patients were managed perioperatively according to a standard institutional protocol, a standardized stepwise positioning, and surgical maneuvers to decrease the risk of venous air embolism (VAE) and other complications...
December 16, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27927759/cd4-8-ratio-above-5-is-associated-with-all-cause-mortality-in-cmv-seronegative-very-old-women-results-from-the-belfrail-study
#13
Wim Adriaensen, Graham Pawelec, Bert Vaes, Klaus Hamprecht, Evelyna Derhovanessian, Gijs van Pottelbergh, Jean-Marie Degryse, Catharina Matheï
The occurrence and general applicability of the CD4:8 ratio as a surrogate predictor of mortality among the oldest old have only been tested in a few longitudinal studies. Here, the predictive value of CD4:8 ratio for mortality with respect to the role of cytomegalovirus (CMV) infection was investigated. Using polychromatic flow cytometry, the CD4:8 ratio and T-cell subsets of 235 individuals aged 81.5 years or older were analyzed, and mortality data were collected after a mean period of 3.3 years. The hazard for all-cause mortality adjusted for age, comorbidity, and CMV serostatus increased 1...
December 7, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/27917737/a-pediatric-approach-to-ventilator-associated-events-surveillance
#14
Noelle M Cocoros, Gregory P Priebe, Latania K Logan, Susan Coffin, Gitte Larsen, Philip Toltzis, Thomas J Sandora, Marvin Harper, Julia S Sammons, James E Gray, Donald Goldmann, Kelly Horan, Michael Burton, Paul A Checchia, Matthew Lakoma, Shannon Sims, Michael Klompas, Grace M Lee
OBJECTIVE Adult ventilator-associated event (VAE) definitions include ventilator-associated conditions (VAC) and subcategories for infection-related ventilator-associated complications (IVAC) and possible ventilator-associated pneumonia (PVAP). We explored these definitions for children. DESIGN Retrospective cohort SETTING Pediatric, cardiac, or neonatal intensive care units (ICUs) in 6 US hospitals PATIENTS Patients ≤18 years old ventilated for ≥1 day METHODS We identified patients with pediatric VAC based on previously proposed criteria...
December 5, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27906047/propranolol-and-survival-from-breast-cancer-a-pooled-analysis-of-european-breast-cancer-cohorts
#15
Chris R Cardwell, Anton Pottegård, Evelien Vaes, Hans Garmo, Liam J Murray, Chris Brown, Pauline A J Vissers, Michael O'Rorke, Kala Visvanathan, Deirdre Cronin-Fenton, Harlinde De Schutter, Mats Lambe, Des G Powe, Myrthe P P van Herk-Sukel, Anna Gavin, Søren Friis, Linda Sharp, Kathleen Bennett
BACKGROUND: Preclinical studies have demonstrated that propranolol inhibits several pathways involved in breast cancer progression and metastasis. We investigated whether breast cancer patients who used propranolol, or other non-selective beta-blockers, had reduced breast cancer-specific or all-cause mortality in eight European cohorts. METHODS: Incident breast cancer patients were identified from eight cancer registries and compiled through the European Cancer Pharmacoepidemiology Network...
December 1, 2016: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/27903565/improving-care-for-heart-failure-patients-in-primary-care-gps-perceptions-a-qualitative-evidence-synthesis
#16
Miek Smeets, Sara Van Roy, Bert Aertgeerts, Mieke Vermandere, Bert Vaes
OBJECTIVES: General practitioners (GPs) play a key role in heart failure (HF) management. Despite multiple guidelines, the management of patients with HF in primary care is suboptimal. Therefore, all the qualitative evidence concerning GPs' perceptions of managing HF in primary care was synthesised to identify barriers and facilitators for optimal care, and ideas for improvement. DESIGN: Qualitative evidence synthesis. METHODS: Searches of MEDLINE, EMBASE, Web of Science and CINAHL databases up to 20/12/2015 were conducted...
November 30, 2016: BMJ Open
https://www.readbyqxmd.com/read/27896454/venous-air-embolism-in-the-sitting-position-in-cranial-neurosurgery-incidence-and-severity-according-to-the-used-monitoring
#17
Franziska Günther, Paul Frank, Makoto Nakamura, Elvis Josef Hermann, Thomas Palmaers
BACKGROUND: There is an ongoing debate about the sitting position (SP) in neurosurgical patients. The SP provides a number of advantages as well as severe complications such as commonly concerning venous air embolism (VAE). The best monitoring system for the detection of VAE is still controversial. METHODS: In this retrospective analysis we compared 208 patients. Transesophageal echocardiography (TEE) or transthoracic Doppler (TTD) were used as monitoring devices to detect VAE; 101 cases were monitored with TEE and 107 with TTD...
February 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27881915/copd-care-delivery-pathways-in-five-european-union-countries-mapping-and-health-care-professionals-perceptions
#18
Reem Kayyali, Bassel Odeh, Inéz Frerichs, Nikki Davies, Eleni Perantoni, Shona D'arcy, Anouk W Vaes, John Chang, Martijn A Spruit, Brenda Deering, Nada Philip, Roshan Siva, Evangelos Kaimakamis, Ioanna Chouvarda, Barbara Pierscionek, Norbert Weiler, Emiel Fm Wouters, Andreas Raptopoulos, Shereen Nabhani-Gebara
BACKGROUND: COPD is among the leading causes of chronic morbidity and mortality in the European Union with an estimated annual economic burden of €25.1 billion. Various care pathways for COPD exist across Europe leading to different responses to similar problems. Determining these differences and the similarities may improve health and the functioning of health services. OBJECTIVE: The aim of this study was to compare COPD patients' care pathway in five European Union countries including England, Ireland, the Netherlands, Greece, and Germany and to explore health care professionals' (HCPs) perceptions about the current pathways...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27880888/evidence-of-a-different-landing-strategy-in-subjects-with-chronic-ankle-instability
#19
Christophe Eechaute, Roel De Ridder, Tom Maes, David Beckwée, Eva Swinnen, Ronald Buyl, Peter Vaes
The purpose of the study is to evaluate the discriminative validity of the multiple hop test (MHT) for chronic ankle instability (CAI). The dynamic postural control of 51 CAI subjects and 52 uninjured controls was assessed using the MHT. To evaluate dynamic postural control, the type and number of balance errors were analysed and the time to complete the MHT was measured. Between-group differences of time scores and balance errors, identified as being change-in-support strategy errors (CSS) or fixed-support strategy errors (FSS), were assessed...
November 2, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27870056/cure-of-cancer-for-seven-cancer-sites-in-the-flemish-region
#20
Geert Silversmit, David Jegou, Evelien Vaes, Elke Van Hoof, Els Goetghebeur, Liesbet Van Eycken
Cumulative relative survival curves for many cancers reach a plateau several years after diagnosis, indicating that the cancer survivor group has reached "statistical" cure. Parametric mixture cure model analysis on grouped relative survival curves provide an interesting way to determine the proportion of statistically cured cases and the mean survival time of the fatal cases in particular for population-based cancer registries. Based on the relative survival data from the Belgian Cancer Registry, parametric cure models were applied to seven cancer sites (cervix, colon, corpus uteri, skin melanoma, pancreas, stomach and oesophagus), at the Flemish Regional level for the incidence period 1999-2011...
March 1, 2017: International Journal of Cancer. Journal International du Cancer
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