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https://www.readbyqxmd.com/read/28335699/approaches-to-paraspinal-tumours-a-technical-note
#1
Arjun Dhar, Sumeet Pawar, Apurva Prasad, P S Ramani
Neurogenic tumours of the paraspinal space can occur in all age groups. It is common in adult population and relatively rare in elderly group. Usually they are benign, but in children, arising from the autonomic system, tends to be malignant in nature. Usually in adults, they arise from peripheral nerve sheath and are labelled as schwannomas. For a given tumour, determination of a correct surgical approach is mandatory to achieve a successful surgical outcome. Several factors like tumour size, histology, involvement of the bony spinal canal, etc...
March 23, 2017: Neurological Research
https://www.readbyqxmd.com/read/28334814/genome-wide-association-study-identifies-novel-susceptible-loci-and-highlights-wnt-beta-catenin-pathway-in-the-development-of-adolescent-idiopathic-scoliosis
#2
Zezhang Zhu, Leilei Xu, Nelson Leung-Sang Tang, Xiaodong Qin, Zhenhua Feng, Weixiang Sun, Weiguo Zhu, Benlong Shi, Peng Liu, Saihu Mao, Jun Qiao, Zhen Liu, Xu Sun, Fangcai Li, Jack Chun-Yiu Cheng, Yong Qiu
The genetic architecture of adolescent idiopathic scoliosis (AIS) remains poorly understood. Here we present the result of a 4-stage genome-wide association study composed of 5,953 AIS patients and 8,137 controls. Overall, we identified three novel susceptible loci including rs7593846 at 2p14 near MEIS1 (Pcombined = 1.19 × 10-13, OR = 1.21, 95% CI = 1.10-1.32), rs7633294 at 3p14.1 near MAGI1 (Pcombined = 1.85 × 10-12, OR = 1.20, 95% CI = 1.09-1.32), and rs9810566 at 3q26.2 near TNIK (Pcombined = 1...
February 28, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28332211/a-multi-channel-block-matching-denoising-algorithm-for-spectral-photon-counting-ct-images
#3
Adam P Harrison, Ziyue Xu, David A Bluemke, Amir Pourmorteza, Daniel J Mollura
PURPOSE: We present a denoising algorithm designed for a whole-body prototype photon-counting computed tomography (PCCT) scanner with up to 4 energy thresholds and associated energy-binned images. METHODS: Spectral PCCT images can exhibit low signal to noise ratios (SNRs) due to the limited photon counts in each simultaneously-acquired energy bin. To help address this, our denoising method exploits the correlation and exact alignment between energy bins, adapting the highly-effective block-matching 3D (BM3D) denoising algorithm for PCCT...
March 23, 2017: Medical Physics
https://www.readbyqxmd.com/read/28329748/extensive-multilevel-split-laminotomy-for-debulking-a-cervicothoracolumbar-nondysraphic-intramedullary-spinal-cord-lipoma-in-a-2-month-old-infant
#4
Ha Son Nguyen, Sean Lew
INTRODUCTION: Laminectomy is the traditional approach for posterior exposure of the spinal canal for tumor resection. Another technique is split laminotomy, which entails the division and retraction of the spinous processes and laminae to access the thecal sac. This technique has been employed for small-segment exposures, but not extensively explored for long-segment exposures. CASE: A 2-month-old male presented with progressive right-leg plegia. MRI of the spine revealed a large, intramedullary spinal-cord lipoma extending from C6 to L5...
March 23, 2017: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28323696/a-new-angled-chisel-for-microendoscopic-decompressive-laminotomy
#5
Shu Nakamura, Motohide Shibayama, Fujio Ito, Yasushi Miura
STUDY DESIGN: A retrospective comparative series study. OBJECTIVE: The aim of the study was to describe a new angled chisel (NAC) that facilitates the osteotomy in microendoscopic decompressive laminotomy (MEDL), and to analyze the clinical and radiologic outcomes using the tool. SUMMARY OF BACKGROUND DATA: MEDL for lumbar spinal stenosis is a minimally invasive surgery. The paraspinous unilateral approach for bilateral decompression can preserve the posterior structure better than other methods...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28323694/assessment-of-paraspinal-muscle-cross-sectional-area-after-lumbar-decompression-minimally-invasive-versus-open-approaches
#6
Lacey E Bresnahan, Justin S Smith, Alfred T Ogden, Steven Quinn, George R Cybulski, Narina Simonian, Raghu N Natarajan, Richard D Fessler, Richard G Fessler
STUDY DESIGN: A retrospective, blinded analysis of imaging studies. SUMMARY OF BACKGROUND DATA: To evaluate changes in paraspinal muscle cross-sectional area (CSA) after surgical treatment for lumbar stenosis and to compare these changes between minimally invasive and standard open approaches. The open approach to lumbar stenosis is effective, but it involves retraction and resection of muscle from the spinous process, which can result in ischemia and denervation of paraspinal musculature and may lead to muscle atrophy and pain...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28323641/metal-artifacts-in-computed-tomography-for-radiation-therapy-planning-dosimetric-effects-and-impact-of-metal-artifact-reduction
#7
Drosoula Giantsoudi, Bruno De Man, Joost Verburg, Alexei Trofimov, Yannan Jin, Ge Wang, Lars Gjesteby, Harald Paganetti
A significant and increasing number of patients receiving radiation therapy present with metal objects close to, or even within, the treatment area, resulting in artifacts in computed tomography (CT) imaging, which is the most commonly used imaging method for treatment planning in radiation therapy. In the presence of metal implants, such as dental fillings in treatment of head-and-neck tumors, spinal stabilization implants in spinal or paraspinal treatment or hip replacements in prostate cancer treatments, the extreme photon absorption by the metal object leads to prominent image artifacts...
March 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28316224/-relief-effect-of-ct-guided-125-i-seed-implantation-on-patients-with-spinal-and-paraspinal-osteolytic-metastatic-tumors
#8
H Huang, F S Li, L Wang, Z G Du, S N Xu
Objective: To evaluate the clinical value of computed tomography (CT)-guided (125)I seed implantation in the treatment of patients with spinal and/or paraspinal osteolytic metastatic tumors. Methods: The radiation dose distribution was planned for 27 patients with 35 spinal and paraspinal osteolytic metastatic tumors by a treatment planning system (TPS). CT-guided (125)I seed implantation was carried out in the patients, and the quality of treatment was evaluated based on CT-imaging follow-up. Results: All the 27 patients underwent CT-guided (125)I seed implantation successfully...
March 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28304239/immunoglobulin-g4-related-epidural-inflammatory-pseudotumor-presenting-with-pulmonary-complications-and-spinal-cord-compression-case-report
#9
Kavelin Rumalla, Kyle A Smith, Paul M Arnold
Immunoglobulin G4-related disease (IgG4-RD) is a recently defined condition characterized by inflammatory tumefactive lesions in various organ systems. IgG4-RD is a clinical and radiological diagnosis of exclusion and requires the presence of specific histopathological criteria for diagnosis. A 50-year-old man presented to an outside hospital with a 3-month history of progressively worsening back pain and symptoms of pleurisy, nasal crusting, and hematochezia. Radiological workup revealed an epidural-paraspinal mass with displacement of the spinal cord, destruction of the T5-6 vertebrae, and extension into the right lung...
March 17, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28304226/integration-of-active-pauses-and-pattern-of-muscular-activity-during-computer-work
#10
Nancy St-Onge, Afshin Samani, Pascal Madeleine
Submaximal isometric muscle contractions have been reported to increase variability of muscle activation during computer work; however, other types of active contractions may be more beneficial. Our objective was to determine which type of active pause vs. rest is more efficient in changing muscle activity pattern during a computer task. Asymptomatic regular computer users performed a standardised 20-min computer task four times, integrating a different type of pause: sub-maximal isometric contraction, dynamic contraction, postural exercise and rest...
March 17, 2017: Ergonomics
https://www.readbyqxmd.com/read/28303561/extraforaminal-lumbar-interbody-fusion-at-the-l5-s1-level-technical-considerations-and-feasibility
#11
Arthur Robert Kurzbuch, Denis Kaech, Pawel Baranowski, Alicja Baranowska, Didier Recoules-Arche
Background Extraforaminal lumbar interbody fusion (ELIF) surgery is a muscle-sparing approach that allows the treatment of various degenerative spinal diseases. It is technical challenging to perform the ELIF approach at the L5-S1 level because the sacral ala obstructs the view of the intervertebral disk space. Methods We reported earlier on the ELIF technique in which the intervertebral disk is targeted at an angle of 45 degrees relative to the midline. In this article we describe the technical process we developed to overcome the anatomic relation between the sacral ala and the intervertebral disk space L5-S1 that hinders the ELIF approach at this level...
March 16, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28299920/cervical-and-lumbar-paraspinal-calcinosis-in-systemic-sclerosis
#12
C K Tan, E Suresh
Calcinosis is a well-recognized manifestation of systemic sclerosis. Paraspinal or intraspinal calcinosis is rare, with reports of calcinosis involving the cervical, thoracic and lumbar separately, but not together. We now report a case of limited cutaneous scleroderma with extensive paraspinal calcinosis of the cervical and lumbar spine.
December 31, 2016: Reumatismo
https://www.readbyqxmd.com/read/28279204/a-study-to-compare-the-efficacy-of-polyether-ether-ketone-rod-device-with-titanium-devices-in-posterior-spinal-fusion-in-a-canine-model
#13
Nanxiang Wang, Huanxin Xie, Chunyang Xi, Han Zhang, Jinglong Yan
BACKGROUND: The benefits of posterior lumbar fusion surgery with orthotopic paraspinal muscle-pediculated bone flaps are well established. However, the problem of non-union due to mechanical support is not completely resolved. The aim of the study was to compare the efficacy of polyether ether ketone (PEEK) rod device with conventional titanium devices in the posterior lumbar fusion surgery with orthotopic paraspinal muscle-pediculated bone flaps. METHODS: This was a randomized controlled study with an experimental animal model...
March 9, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28277476/viability-and-biomechanics-of-bare-diced-cartilage-grafts-in-experimental-study
#14
Jun-Lin Liao, Jia Chen, Jia-Qin Xu, Yan Cheng, Hong-Ju Xie, Gu He, Bin He, Ke Cao, Hui-Qing Xie, Jian-Da Zhou
OBJECTIVE: To assess the viability and biomechanics of bare diced cartilage grafts. METHODS: Cartilage samples were collected from 1 ear in 15 rabbits as well as costal cartilage. Each rabbit was inserted bare diced- and single-strip costal-cartilage grafts, respectively, into paraspinal subcutaneous pockets: after euthanasia at 2 months, specimens were weighed, with diced cartilage grafts examined histomorphologically by hematoxylin-eosin staining, masson trichrome staining, and immunohistochemistry...
March 8, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28270941/a-lip-lump-an-unexpected-histological-diagnosis-of-a-lip-schwannoma
#15
Thomas Haigh, John Raad Glore, David Gouldesbrough, Winson Wong
Schwannomas are benign nerve sheath tumours arising from Schwann cells. They comprise 1% of all benign tumours. In the 2016 World Health Organisation Classification of Central Nervous System, they are classified as a tumour of the cranial and paraspinal nerves, Schwannoma 9560/0. A 23-year-old Caucasian lady presented with a seven-month history of a painless right upper lip lump. Examination revealed a small cystic 0.5 cm diameter lesion within the right upper lip. The clinical impression was that of a mucocele...
2017: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/28266959/morphometric-analysis-of-the-retroperitoneal-vessels-with-respect-to-lateral-access-surgery-in-adult-scoliosis
#16
Heeren S Makanji, Hai Le, Kirkham B Wood, Louis G Jenis, Thomas D Cha
STUDY DESIGN: Cross-sectional study reviewing 62 magnetic resonance imaging or computed tomography scans from consecutive adult patients with scoliotic spinal deformity in the thoracolumbar spine. OBJECTIVE: To investigate the variation in anatomic position of retroperitoneal vessels in relationship to curve direction, location, magnitude, and axial rotation of curves in adult scoliosis. SUMMARY OF BACKGROUND DATA: The minimally invasive lateral approach to the thoracolumbar spine avoids manipulation of abdominal and retroperitoneal structures and decreases risk of injury to paraspinal musculature...
March 6, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28266956/iatrogenic-flatback-and-flatback-syndrome-evaluation-management-and-prevention
#17
Barrett S Boody, Brett D Rosenthal, Tyler J Jenkins, Alpesh A Patel, Jason W Savage, Wellington K Hsu
Flatback syndrome can be a significant source of disability, affecting stance and gait, and resulting in significant pain. Although the historical instrumentation options for thoracolumbar fusion procedures have been commonly regarded as the etiology of iatrogenic flatback, inappropriate selection, or application of modern instrumentation can similarly produce flatback deformities. Patients initially compensate with increased lordosis at adjacent lumbar segments and reduction of thoracic kyphosis. As paraspinal musculature fatigues and discs degenerate, maintaining sagittal balance requires increasing pelvic retroversion and hip extension...
March 6, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28264250/an-intradiscal-granuloma-due-to-a-retained-wooden-foreign-body
#18
Mehmet Arif Aladag, Mehmet Akif Durak
We report a patient with a wooden foreign body granuloma in the intervertebral disc space being symptomatic 17 years after a paraspinal penetrant trauma. According to the our result of the search for wooden foreign body granulomas, this is the first case suffered from a wooden foreign body granuloma in the intervertebral disc space that reported in the literature. In this report, we emphasized the importance of rigorous examination and follow up in paraspinal wooden penetrant traumas.
March 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28259858/posterior-fossa-decompression-in-chiari-i-improves-denervation-of-the-paraspinal-muscles
#19
Shifu Sha, Yang Li, Yong Qiu, Zhen Liu, Xu Sun, Weiguo Zhu, Zhenhua Feng, Tao Wu, Jian Jiang, Zezhang Zhu
OBJECTIVE: To investigate whether posterior fossa decompression (PFD) could improve denervation of the paraspinal muscles in patients with Chiari I malformation (CMI). BACKGROUND: Paraspinal muscle denervation is one of the essential elements in the pathophysiology of CMI/syringomyelia-related scoliosis. Although PFD has been widely used for managing CMI, whether denervation of the paraspinal muscles may benefit from this neurosurgical procedure remains ambiguous...
March 4, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28259005/removal-of-fixation-construct-could-mitigate-adjacent-segment-stress-after-lumbosacral-fusion-a-finite-element-analysis
#20
Yueh-Ying Hsieh, Chia-Hsien Chen, Fon-Yih Tsuang, Lien-Chen Wu, Shang-Chih Lin, Chang-Jung Chiang
BACKGROUND DATA: Combined usage of posterior lumbar interbody fusion and transpedicular fixation has been extensively used to treat the various lumbar degenerative disc diseases. The transpedicular fixator aims to increase stability and enhance the fusion rate. However, how the fused disc and bridged vertebrae respectively affect adjacent-segment diseases progression is not yet clear. METHODS: Using a validated lumbosacral finite-element model, three variations at the L4-L5 segment were analyzed: 1) moderate disc degeneration, 2) instrumented with a stand-alone cage and pedicle screw fixators, and 3) with the cage only after fusion...
February 23, 2017: Clinical Biomechanics
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