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https://www.readbyqxmd.com/read/29901559/aneursymal-bone-cyst-an-uncommon-paraspinal-tumor-in-children
#1
Nilay Shah, Thomas Scharschmidt, Bonita Fung, Miriam Conces, Bhuvana A Setty
Paraspinal tumors with benign histology in the absence of trauma rarely arise in children. Treatment of such benign tumors, in contrast to malignancies, generally consists of surgical resection of the lesion with confirmation of histology via pathologic evaluation. We present a pediatric case of an atraumatic paraspinal mass with a histologic diagnosis of aneurysmal bone cyst, and USP6 gene rearrangement supporting the histologic diagnosis. The patient underwent gross total resection of the paraspinal lesion with no additional intervention...
June 12, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29890458/local-muscle-flaps-minimize-post-operative-wound-morbidity-in-patients-with-neoplastic-disease-of-the-spine
#2
Philipp Franck, Jaime L Bernstein, Leslie E Cohen, Roger Härtl, Ali A Baaj, Jason A Spector
OBJECTIVES: Patients with neoplastic disease involving the spine either from primary or metastatic disease present a unique challenge given these patients' frequent poor nutritional status at the time of surgery, the delivery of early post-operative chemotherapy or radiation, and placement of large amounts of hardware and avascular bone graft into a wound bed that is atrophic, previously operated or irradiated. As a result, wound morbidity has traditionally been high in this cohort of patients...
May 29, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29881155/unilateral-biportal-endoscopic-decompression-by-30%C3%A2-endoscopy-in-lumbar-spinal-stenosis-technical-note-and-preliminary-report
#3
Ju-Eun Kim, Dae-Jung Choi
Background context: Open laminectomy has been regarded as the standard surgical method up to date in degenerative spinal stenosis or herniation of intervertebral disc. The conventional method may lead to instability and provoke chronic lower back pain by scarifying facet joint, posterior ligamentous complex as well as paraspinal muscle. For this reason, the new technique using an endoscope, which could protect soft tissue and facet joint, recently got spotlight. Purpose: The aim of this study is to introduce a new spinal surgical technique using a 30-degreed endoscopy through bi- or tri- portals and to report the preliminary result of this technique...
June 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29879780/clinical-correlation-between-muscle-damage-and-oswestry-disability-index-score-after-open-lumbar-surgery-does-open-surgery-reduces-functional-ability
#4
Rushama Tandon, Vivek Kiyawat, Neeraj Kumar
STUDY DESIGN: Single-surgeon, single-center prospective study with prospective data collection. PURPOSE: To clinically evaluate muscle damage after open lumbar surgery and its relationship to functional activity and to validatethe improvement in function as indicated by improved Oswestry Disability Index (ODI) score despite muscle damage. OVERVIEW OF LITERATURE: Few studies have analyzed the functional loss and recovery pattern of muscles after open lumbar surgery...
June 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29866071/disseminated-exophiala-dermatitidis-causing-septic-arthritis-and-osteomyelitis
#5
Raynell Lang, Jessica Minion, Stuart Skinner, Alexander Wong
BACKGROUND: Exophiala dermatitidis is a melanized fungus isolated from many environmental sources. Infections caused by Exophiala species are typically seen in immunocompromised hosts and manifest most commonly as cutaneous or subcutaneous disease. Systemic infections are exceedingly rare and associated with significant morbidity and mortality CASE PRESENTATION: A 28-year-old female originally from India presented with fevers, chills, weight loss and increasing back pain. She had a recent diffuse maculopapular rash that resulted in skin biopsy and a tentative diagnosis of sarcoidosis, leading to administration of azathioprine and prednisone...
June 4, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29844925/decompression-for-botulinum-toxin-exacerbated-cervical-myeloradiculopathy-in-the-setting-of-congenital-stenosis-and-arnold-chiari-i-malformation
#6
Abhinav Mohan, Eric Chang
Introduction: We present a case describing the management of a woman with severe, functionally limiting cervical myeloradiculopathy in the setting of congenital cervical canal stenosis and Arnold-Chiari I malformation. Case presentation: The subject is a 57-year-old woman with prior anterior cervical discectomy and fusion who presented with left-sided neck pain associated with radiculopathy, migraine, gait incoordination, and cervical dystonia. Cervical stenosis and Chiari malformation were confirmed using MRI...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29794943/erector-spinae-plane-block-versus-retrolaminar-block-a-magnetic-resonance-imaging-and-anatomical-study
#7
Sanjib Das Adhikary, Stephanie Bernard, Hector Lopez, Ki Jinn Chin
BACKGROUND AND OBJECTIVES: The erector spinae plane (ESP) and retrolaminar blocks are ultrasound-guided techniques for thoracoabdominal wall analgesia involving injection into the musculofascial plane between the paraspinal back muscles and underlying thoracic vertebrae. The ESP block targets the tips of the transverse processes, whereas the retrolaminar block targets the laminae. We investigated if there were differences in injectate spread between the 2 techniques that would have implications for their clinical effect...
May 23, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29788907/mycobacterium-avium-complex-vertebral-osteomyelitis-in-the-absence-of-hiv-infection-a-case-report-and-review
#8
Megan E Gray, Peter W Liu, Brian Wispelwey
BACKGROUND: Mycobacterium Avium Complex (MAC) is an established microbiologic cause of pulmonary disease, lymphadenitis, and disseminated disease in cases of advanced immune suppression. However, MAC manifesting as vertebral osteomyelitis is less common, and is particularly rare in the absence of Acquired Immunodeficiency Syndrome (AIDS). Prompt diagnosis of MAC vertebral osteomyelitis is challenging, but necessary to prevent serious morbidity or mortality. CASE PRESENTATION: We report a case of MAC osteomyelitis of the lumbar spine in a 70-year-old woman on extended duration corticosteroid therapy for systemic lupus erythematosus who presented with progressive back pain...
May 22, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29787880/comparison-of-surgical-invasiveness-between-microdiscectomy-and-three-different-endoscopic-discectomy-techniques-for-lumbar-disc-herniation
#9
Kyung-Chul Choi, Hyeong-Ki Shim, Jin-Sup Hwang, Seung Ho Shin, Dong Chan Lee, Hwan Hui Jung, Hyeon Ah Park, Choon-Keun Park
OBJECTIVE: Muscle injury is inevitable during surgical exposure of the spine. This study was conducted to investigate paraspinal muscle injury after the following four surgical techniques: microdiscectomy (MD), percutaneous endoscopic lumbar discectomy (PELD), percutaneous endoscopic interlaminar discectomy (PEID), and unilateral biportal endoscopic discectomy (UBED). METHODS: Eighty patients who underwent the four surgical techniques were prospectively observed...
May 19, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29787423/autoimmune-granulomatous-inflammation-of-lacrimal-glands-and-axonal-neuritis-following-treatment-with-ipilimumab-and-radiation-therapy
#10
Ecaterina Ileana Dumbrava, Veronica Smith, Rasha Alfattal, Adel K El-Naggar, Marta Penas-Prado, Apostolia M Tsimberidou
Immune checkpoint inhibitors such as anti-CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), anti PD-1 (programmed cell death protein 1) and PD-L1 (programmed cell death protein-ligand 1) monoclonal antibodies are emerging as standard oncology treatments in various tumor types. The indications will expand as immunotherapies are being investigated in various tumors with promising results. Currently, there is inadequate identification of predictive biomarkers of response or toxicity. Unique response patterns include pseudoprogression and delayed response...
May 21, 2018: Journal of Immunotherapy
https://www.readbyqxmd.com/read/29775800/insertion-and-presence-of-fine-wire-intramuscular-electrodes-to-the-lumbar-paraspinal-muscles-do-not-affect-muscle-performance-and-activation-during-high-exertion-spinal-extension-activities
#11
Szu-Ping Lee, Jo Armour Smith, Matthew Kimber, Kelsey Houk
BACKGROUND: Low back pain (LBP) is commonly associated with paraspinal muscle dysfunctions. A method to study deep lumbar paraspinal (i.e. multifidus) muscle function and neuromuscular activation pattern is intramuscular electromyography (EMG). Previous studies have shown that the procedure does not significantly impact muscle function during activities involving low-level muscle contractions. However, it is currently unknown how muscular function and activation are affected during high-exertion contractions...
May 15, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29774199/malignant-metastasis-misdiagnosed-as-osteoporotic-compression-fracture-a-case-report
#12
Seul Gi Kim, Chang Il Ju, Hui Sun Wang, Seok Won Kim
In cases of vertebral collapse after a trivial injury in elderly patients with severe osteoporosis, it can be a diagnostic challenge to determine whether the cause is a benign compression fracture or malignant metastasis. A 78-year-old male patient was referred to the emergency department for the evaluation of weakness of the left lower limb. He had undergone percutaneous vertebroplasty four months earlier after being diagnosed with L3 osteoporotic compression fracture. He was treated with foraminotomy at the L3-4 level after being diagnosed with foraminal stenosis two months earlier at a spine clinic...
April 2018: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29772498/test-retest-reliability-of-laser-displacement-mechanomyography-in-paraspinal-muscles-while-in-lumbar-extension-or-flexion
#13
Christian Than, Laura Seidl, Danijel Tosovic, J Mark Brown
This study investigated test-retest reliability of mechanomyography (MMG) on lumbar paraspinal muscles. Healthy male and female subjects (mean ± standard deviation, 25 ± 9.4 years, BMI 21.8 ± 2.99, n = 34) were recruited. Two test sessions (one week apart) consisted of MMG (laser displacement sensor (LDS)) muscle evaluations over the 10 lumbar facet joints, and 2 bilateral sacral sites, in anatomical extension and flexion. Two-way repeated measures ANOVA with Tukey's post hoc showed no significant differences between testing sessions for the same position (p > 0...
May 12, 2018: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29772368/volumetric-muscle-measurements-indicate-significant-muscle-degeneration-in-single-level-disc-herniation-patients
#14
Kaan Yaltırık, Burhan Oral Güdü, Yüksel Işık, Çiğdem Altunok, Ufuk Tipi, Başar Atalay
INTRODUCTION: There is a strong relationship between lower back pain and paraspinal muscle atrophy. In this study, we aimed to investigate the prevalence of lumbar paravertebral muscle atrophy in patients with and without single level disc herniation. MATERIALS AND METHODS: The 110 retrospectively analyzed patients in this study were divided into two groups. Group A included 55 patients with radiologically confirmed single level disc herniation with back pain and radiculopathy...
May 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29766758/anti-inflammatory-peptide-attenuates-edema-and-promotes-bmp-2-induced-bone-formation-in-spine-fusion
#15
Juliane D Glaeser, Khosrowdad Salehi, Linda Kanim, Dmitriy Sheyn, Zachary NaPier, Phillip Behrens, Leslie Garcia, Jason M Cuéllar, Hyun W Bae
Recombinant human bone morphogenic protein-2 (BMP-2) loaded absorbable collagen sponges (ACS) have been successfully used to enhance bone formation and to induce spinal fusion in humans. However, side effects, such as soft-tissue edema and inflammation, have been reported. NEMO binding domain peptide (NBD) inhibits activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), a central regulator of immune response. In this study, we investigated NBD's potential to reduce BMP-2-induced soft-tissue inflammation without affecting BMP-2-mediated spinal fusion in rat...
May 16, 2018: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29759081/comparative-study-of-the-paraspinal-muscles-after-ovf-between-the-insufficient-union-and-sufficient-union-using-mri
#16
Marina Katsu, Tetsuro Ohba, Shigeto Ebata, Hirotaka Haro
BACKGROUND: Identification of poor prognostic factors for OVF is important but has not yet been clearly established. Despite paraspinal muscles could play an important role in the etiology of OVF, what influence time-dependent changes in paraspinal muscles have after OVF, and the impact on conservative treatments for patients who have an OVF remain largely unknown. The purposes of this study were to (1) evaluate time-dependent changes of the paraspinal musculature using MRI after injury in patients with osteoporotic vertebral fractures (OVFs), and (2) compare paraspinal muscles between conservatively treated patients with OVF who have successful union and those failed to conservative treatment...
May 14, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29757449/composite-hemangioendothelioma-settled-in-the-paraspinal-region-a-rare-case-report
#17
Sevki Gok, Mehmet Zafer Berkman, Eyup Baykara
Composite Hemangioendothelioma (CHE) is a very rare, low-grade malignant vascular tumor. It is most commonly seen as one or more nodules on both sides of the fingers and toes. This tumor is rarely settled in the paraspinal muscles. The age of onset is usually between the ages of 21 and 72 (1), with average age of 39.5-41 years. The treatment is gross total removal of the lesion. The definitive diagnosis is made histopathologically. Our case was a 54-year-old male patient. He had a complaint of low back pain...
April 24, 2018: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29734942/methodological-considerations-in-region-of-interest-definitions-for-paraspinal-muscles-in-axial-mris-of-the-lumbar-spine
#18
David B Berry, Jennifer Padwal, Seth Johnson, Callan L Parra, Samuel R Ward, Bahar Shahidi
BACKGROUND: Magnetic Resonance Imaging (MRI) is commonly used to assess the health of the lumbar spine and supporting structures. Studies have suggested that fatty infiltration of the posterior lumbar muscles is important in predicting responses to treatment for low back pain. However, methodological differences exist in defining the region of interest (ROI) of a muscle, which limits the ability to compare data between studies. The purpose of this study was to determine reliability and systematic differences within and between two commonly utilized methodologies for ROI definitions of lumbar paraspinal muscle...
May 7, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29734190/severe-pain-due-to-paraspinal-abscess-formation-in-two-patients-with-squamous-cell-carcinoma-of-the-head-and-neck-after-multimodal-treatment-including-cetuximab
#19
Christina Gerlach, Ina Pretzell, Elisabeth Lieberknecht, Stefan Mattyasovszky, Martin Weber
No abstract text is available yet for this article.
May 3, 2018: Oncology Research and Treatment
https://www.readbyqxmd.com/read/29721349/abscess-due-to-textiloma-gossypiboma-retained-surgical-cottonoid
#20
Ali Akhaddar, Hassan Baallal, Abderrahim Elktaibi
Background: Surgical site infections following spinal surgery, including spinal abscesses, are rare but serious as they are major causes of morbidity, and even mortality. They are, however, rarely attributed to infected, retained surgical cottonoids or sponges (textiloma or gossypiboma) inadvertently left in an operative field. Case Description: A 53-year-old female with a history of two prior spinal operations at the L4-S1 levels (11 and 2 years previously) presented over a few weeks with the acute onset of a cauda equina syndrome (e...
2018: Surgical Neurology International
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