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accelerated partial breast irradiation

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https://www.readbyqxmd.com/read/27898749/-dosimetric-comparison-of-different-techniques-for-external-beam-accelerated-partial-breast-irradiation
#1
Gábor Stelczer, Tibor Major, Norbert Mészáros, Csaba Polgár, Csilla Pesznyák
The aim of this article is to evaluate and compare four different radiotherapy techniques of accelerated partial breast irradiation (APBI) considering planning quality, dosimetric and practical aspects. The investigated techniques are three dimensional conformal radiotherapy (3D-CRT), "step and shoot" (SS) and "sliding window" (SW) intensity-modulated radiotherapy, intensity-modulated arc therapy (RA). CT scans of 10 patients previously treated with APBI were selected for the study. Surgical clips were placed on the borders of the tumour bed during breast conserving surgery...
November 29, 2016: Magyar Onkologia
https://www.readbyqxmd.com/read/27872946/implementation-of-image-guided-intensity-modulated-accelerated-partial-breast-irradiation-three-year-results-of-a%C3%A2-phase%C3%A2-ii-clinical-study
#2
Norbert Mészáros, Tibor Major, Gábor Stelczer, Zoltán Zaka, Emőke Mózsa, Dávid Pukancsik, Zoltán Takácsi-Nagy, János Fodor, Csaba Polgár
PURPOSE: To report 3‑year results of accelerated partial breast irradiation (APBI) using image-guided intensity-modulated radiotherapy (IG-IMRT) following breast conserving surgery (BCS) for low-risk early invasive breast cancer. PATIENTS AND METHODS: Between July 2011 and March 2014, 60 patients with low-risk early invasive breast cancer underwent BCS and were enrolled in this phase II prospective study. The total dose was 36.9 Gy (9 fractions of 4.1 Gy, two fractions/day)...
November 21, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27869081/long-term-update-of-nrg-oncology-rtog-0319-a-phase-1-and-2%C3%A2-trial-to-evaluate-3-dimensional-conformal-radiation-therapy-confined-to-the-region-of%C3%A2-the%C3%A2-lumpectomy-cavity-for-stage-i-and-ii-breast%C3%A2-carcinoma
#3
Rachel Rabinovitch, Jennifer Moughan, Frank Vicini, Helen Pass, John Wong, Susan Chafe, Ivy Petersen, Douglas W Arthur, Julia White
PURPOSE: NRG Oncology RTOG 0319 was the first cooperative group trial in the United States to evaluate 3-dimensional conformal radiation therapy (3D-CRT) accelerated partial breast irradiation (APBI). This report updates secondary endpoints of toxicity and efficacy. METHODS AND MATERIALS: Patients with stage I or II invasive breast cancer (tumor size ≤3 cm, ≤3 positive lymph nodes, negative margins) were eligible for 3D-CRT APBI: 38.5 Gy in 10 twice-daily fractions...
December 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27866865/accelerated-partial-breast-irradiation-executive-summary-for-the-update-of-an-astro-evidence-based-consensus-statement
#4
Candace Correa, Eleanor E Harris, Maria Cristina Leonardi, Benjamin D Smith, Alphonse G Taghian, Alastair M Thompson, Julia White, Jay R Harris
PURPOSE: To update the accelerated partial breast irradiation Consensus Statement published in 2009 and provide guidance on use of intraoperative radiation therapy (IORT) for partial breast irradiation in early-stage breast cancer, based on published evidence complemented by expert opinion. METHODS AND MATERIALS: A systematic PubMed search using the same terms as the original Consensus Statement yielded 419 articles; 44 articles were selected. The authors synthesized the published evidence and, through a series of conference calls and e-mails, reached consensus regarding the recommendations...
September 17, 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/27837457/external-radiotherapy-for-breast-cancer-in-the-elderly
#5
REVIEW
Francesca Maria Giugliano, Sara Falivene, Emanuela Esposito, Rossella Di Franco, Matteo Muto, Massimiliano D'Aiuto, Paolo Muto
BACKGROUND: Breast cancer is the most common malignancy amongst elderly women and the main cause of mortality. A specific management for elderly woman is not clear because clinical trials are usually not customized for this subset of patients. AIMS: The aim of this paper is to provide an overview of the available information on the main issues in the field of breast cancer radiotherapy in the elderly population. MATERIALS AND METHODS: Authors discuss on different radiation treatments for breast cancer in the elderly, based on the data of the literature with a focus on new strategy: hypo-fractionation, accelerated partial breast irradiation, and the utility of a dose boost...
November 11, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27816540/frequency-of-whole-breast-radiation-therapy-after-intraoperative-radiation-therapy-due-to-criteria-identified-by-lumpectomy
#6
Eric A Mellon, Amber Orman, Luis E Joya, Michael E Montejo, Christine Laronga, Susan J Hoover, M Catherine Lee, Nazanin Khakpour, Pamela F Kubal, Roberto Diaz
PURPOSE: For selected early breast cancers, intraoperative radiation therapy (IORT) at the time of lumpectomy can be an efficient alternative to fractionated whole breast radiation therapy (WBRT). However, some patients are later recommended WBRT after IORT due to surgical pathologic findings. To understand risk factor identification rates triggering WBRT recommendation, we analyzed adverse prognostic features based on multiple international criteria for suitability for accelerated partial breast irradiation...
November 2, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27803959/accelerated-partial-breast-irradiation-with-external-beam-radiotherapy-first-results-of-the-german-phase%C3%A2-2-trial
#7
Oliver J Ott, Vratislav Strnad, Wilhelm Stillkrieg, Wolfgang Uter, Matthias W Beckmann, Rainer Fietkau
BACKGROUND AND PURPOSE: To evaluate the feasibility and efficacy of external beam three-dimensional (3D) conformal accelerated partial breast irradiation (APBI) for selected patients with early breast cancer. PATIENTS AND METHODS: Between 2011 and 2016, 72 patients were recruited for this prospective phase 2 trial. Patients were eligible for APBI if they had histologically confirmed breast cancer or pure ductal carcinoma in situ (DCIS), a tumor diameter ≤3 cm, clear resection margins ≥2 mm, no axillary lymph node involvement, no distant metastases, tumor bed clips, and were aged ≥50 years...
November 1, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27788951/magnetic-resonance-image-guided-radiation-therapy-for-external-beam-accelerated-partial-breast-irradiation-evaluation-of-delivered-dose-and-intrafractional-cavity-motion
#8
Sahaja Acharya, Benjamin W Fischer-Valuck, Thomas R Mazur, Austen Curcuru, Karl Sona, Rojano Kashani, Olga Green, Laura Ochoa, Sasa Mutic, Imran Zoberi, H Harold Li, Maria A Thomas
PURPOSE: To use magnetic resonance image guided radiation therapy (MR-IGRT) for accelerated partial-breast irradiation (APBI) to (1) determine intrafractional motion of the breast surgical cavity; and (2) assess delivered dose versus planned dose. METHODS AND MATERIALS: Thirty women with breast cancer (stages 0-I) who underwent breast-conserving surgery were enrolled in a prospective registry evaluating APBI using a 0.35-T MR-IGRT system. Clinical target volume was defined as the surgical cavity plus a 1-cm margin (excluding chest wall, pectoral muscles, and 5 mm from skin)...
November 15, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27777879/accelerated-partial-breast-irradiation-past-present-and-future
#9
REVIEW
Anne W Tann, Sandra S Hatch, Melissa M Joyner, Lee R Wiederhold, Todd A Swanson
Accelerated partial breast irradiation (APBI) focuses higher doses of radiation during a shorter interval to the lumpectomy cavity, in the setting of breast conserving therapy for early stage breast cancer. The utilization of APBI has increased in the past decade because of the shorter treatment schedule and a growing body of outcome data showing positive cosmetic outcomes and high local control rates in selected patients undergoing breast conserving therapy. Technological advances in various APBI modalities, including intracavitary and interstitial brachytherapy, intraoperative radiation therapy, and external beam radiation therapy, have made APBI more accessible in the community...
October 10, 2016: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27743957/locoregional-recurrence-by-molecular-subtype-after-multicatheter-interstitial-accelerated-partial-breast-irradiation-results-from-the-pooled-registry-of-multicatheter-interstitial-sites-research-group
#10
Bethany M Anderson, Mitchell Kamrava, Pin-Chieh Wang, Peter Chen, D Jeffrey Demanes, John K Hayes, Robert R Kuske
PURPOSE: To determine in breast tumor recurrence (IBTR) and regional nodal recurrence (RNR) rates for women treated with multicatheter interstitial accelerated partial breast irradiation. METHODS AND MATERIALS: Data from five institutions were collected for patients treated from 1992 to 2013. We report outcomes of 582 breast cancers with ≥1 year of followup. Molecular subtype approximation was performed using estrogen receptor, progesterone receptor, Her2, and grade...
October 12, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27709273/impact-of-a-novel-bioabsorbable-implant-on-radiation-treatment-planning-for-breast-cancer
#11
Michael J Cross, Gail S Lebovic, Joseph Ross, Scott Jones, Arnold Smith, Steven Harms
BACKGROUND: Techniques for accurately delineating the tumor bed after breast-conserving surgery (BCS) can be challenging. As a result, the accuracy, and efficiency of radiation treatment (RT) planning can be negatively impacted. Surgically placed clips or the post-surgical seroma are commonly used to determine target volume; however, these methods can lead to a high degree of uncertainty and variability. A novel 3-dimensional bioabsorbable marker was used during BCS and assessed for its impact on RT planning...
October 5, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27675994/time-compressed-2-day-brachytherapy-accelerated-partial-breast-irradiation-versus-hypofractionated-whole-breast-external-beam-radiation-for-early-stage-breast-cancer-a-comparative-analysis-of-clinical-effectiveness-late-toxicities-and-cosmesis
#12
P Y Chen, M Wallace, H Ye, M S Jawad, J T Dilworth, B Wilkinson, I S Grills, G S Gustafson
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675373/dosimetric-feasibility-of-preoperative-partial-breast-irradiation-in-prone-position-using-a-magnetic-resonance-linear-accelerator
#13
P W Prior, A D Currey, T R Kelly, J A Bovi, C Bergom, A Li
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675232/dosimetric-comparison-of-robotic-imrt-and-partial-arc-vmat-in-accelerated-partial-breast-irradiation-apbi-for-early-breast-cancer
#14
S Y Kim, J H Kim, J Y Woo, J G Baek, K S Park, M J Kim, J H Cho
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675211/comparative-analysis-of-strut-based-high-dose-rate-brachytherapy-versus-intensity-modulated-proton-therapy-for-delivery-of-accelerated-partial-breast-irradiation
#15
P Y Chen, Y Wang, J Zhou, X Ding
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675130/the-influence-of-tumor-location-on-cosmesis-and-toxicity-after-interstitial-brachytherapy-accelerated-partial-breast-irradiation
#16
L A Smith, R R Kuske, M Elmore
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674935/discrepancies-in-accelerated-partial-breast-irradiation-apbi-treatment-outcomes-in-younger-women-when-using-claims-versus-a-database-promis-with-actual-recurrence-rates
#17
R R Kuske, J Demanes, B M Anderson, P Y Chen, J K Hayes, C A Quiet, J Wang, D Veruttipong, M Kamrava
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674775/first-ever-magnetic-resonance-image-guided-radiation-therapy-for-accelerated-partial-breast-irradiation-early-results-of-a-single-institution-s-prospective-experience
#18
I Zoberi, M A Thomas, A Curcuru, O L Green, L L Ochoa, R Kashani
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674724/analysis-of-air-cavity-volume-change-in-balloon-based-high-dose-rate-accelerated-partial-breast-irradiation
#19
R Ma, D Zheng, S Wang, X Zhu, N R Bennion, C A Enke, S Zhou, A O Wahl
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674723/five-year-outcomes-of-accelerated-partial-breast-irradiation-apbi-from-a-large-community-based-practice
#20
N A Madden, J Buckner, I Abdalla
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
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