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https://www.readbyqxmd.com/read/29453817/endocrine-and-psychological-aspects-of-sexual-dysfunction-in-klinefelter-patients
#1
A Ferlin, R Selice, S Angelini, M Di Grazia, N Caretta, F Cavalieri, A Di Mambro, C Foresta
Klinefelter syndrome is a frequent cause of hypogonadism, but despite hundreds of publications on different aspects of Klinefelter syndrome, only a few studies dealt with sexual dysfunction. In particular, testosterone is critical for various aspects of sexual response, but its role on sexuality in Klinefelter syndrome patients is debatable and no studies have evaluated the efficacy of testosterone treatment on sexual dysfunction in these subjects. Furthermore, the impact of psychological and relational aspects on sexual function of Klinefelter syndrome subjects is poorly defined...
February 17, 2018: Andrology
https://www.readbyqxmd.com/read/29453658/high-intensity-focused-ultrasound-hifu-therapy-for-benign-thyroid-nodules-without-anesthesia-or-sedation
#2
Pierpaolo Trimboli, Fabiano Bini, Franco Marinozzi, Jung Hwan Baek, Luca Giovanella
BACKGROUND: Thermal ablation of thyroid nodules has gained momentum due to the possibility to avoid surgery. High-intensity focused ultrasound (HIFU) allows thermal treatment by energy ultrasound beam inside the targeted zone. Aim of our study was to evaluate the effects of HIFU treatment using Beamotion mode without anesthesia. METHODS: Since 2016, patients with normal thyroid function, benign thyroid nodules with diameter no larger than 4 cm, and presenting local discomfort and/or compressive symptoms were treated by HIFU...
February 16, 2018: Endocrine
https://www.readbyqxmd.com/read/29453349/ultrasound-and-shock-wave-stimulation-to-promote-axonal-regeneration-following-nerve-surgery-a-systematic-review-and-meta-analysis-of-preclinical-studies
#3
Simeon C Daeschler, Leila Harhaus, Philipp Schoenle, Arne Boecker, Ulrich Kneser, Konstantin D Bergmeister
Limited regeneration after nerve injury often leads to delayed or incomplete reinnervation and consequently insufficient muscle function. Following nerve surgery, application of low-intensity ultrasound or extracorporeal shock waves may promote nerve regeneration and improve functional outcomes. Because currently clinical data is unavailable, we performed a meta-analysis following the PRISMA-guidelines to investigate the therapeutic effect of ultrasound and shock wave therapies on motor nerve regeneration. Ten ultrasound-studies (N = 445 rats) and three shock-wave studies (N = 110 rats) were identified from multiple databases...
February 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29453071/degradation-of-dye-procion-red-mx-5b-by-electrolytic-and-electro-irradiated-technologies-using-diamond-electrodes
#4
Salvador Cotillas, Davide Clematis, Pablo Cañizares, Maria Paola Carpanese, Manuel A Rodrigo, Marco Panizza
This work focuses on the treatment of synthetic wastewater polluted with dye Procion Red MX-5B by different Electrochemical Advanced Oxidation Processes (EAOP) based on diamond anodes. The influence of the current density and the supporting electrolyte has been studied on dye removal and total mineralization of the organic matter. Results show that electrolysis with diamond electrodes is a suitable technology for an efficient degradation of dye. Nonetheless, the process efficiency increases when using chloride as supporting electrolyte because of the electrochemical generation of hypochlorite in wastewater which significantly contribute to dye removal...
February 3, 2018: Chemosphere
https://www.readbyqxmd.com/read/29452833/endothelial-vascular-cell-adhesion-molecule-1-is-a-marker-for-high-risk-carotid-plaques-and-target-for-ultrasound-molecular-imaging
#5
Craig C Weinkauf, Kirsten Concha-Moore, Jonathan R Lindner, Edmund R Marinelli, Kyle P Hadinger, Sandipan Bhattacharjee, Scott S Berman, Kay Goshima, Luis R Leon, Terry O Matsunaga, Evan Unger
BACKGROUND: Molecular imaging of carotid plaque vulnerability to atheroembolic events is likely to lead to improvements in selection of patients for carotid endarterectomy (CEA). The aims of this study were to assess the relative value of endothelial inflammatory markers for this application and to develop molecular ultrasound contrast agents for their imaging. METHODS: Human CEA specimens were obtained prospectively from asymptomatic (30) and symptomatic (30) patients...
February 13, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29452581/prospective-observational-study-on-assessing-the-hemodynamic-relevance-of-patent-ductus-arteriosus-with-frequency-domain-near-infrared-spectroscopy
#6
Christoph E Schwarz, Antonio Preusche, Martin Wolf, Christian F Poets, Axel R Franz
BACKGROUND: What constitutes a hemodynamically relevant patent ductus arteriosus (hrPDA) in preterm infants is unclear. Different clinical and echocardiographic parameters are used, but a gold standard definition is lacking. Our objective was to evaluate associations between regional cerebral tissue oxygen saturation (rcStO 2 ), fraction of tissue oxygen extraction (rcFtO 2 E) measured by frequency domain near-infrared spectroscopy (fd-NIRS) and their correlation to echocardiographic, Doppler-ultrasound, and clinical parameters in preterm infants with and without a hrPDA...
February 16, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29452209/prolactin-improves-hepatic-steatosis-via-cd36-pathway
#7
Pengzi Zhang, Zhijuan Ge, Hongdong Wang, Wenhuan Feng, Xitai Sun, Xuehui Chu, Can Jiang, Yan Wang, Dalong Zhu, Yan Bi
BACKGROUND & AIMS: Prolactin (PRL) is a multifunctional polypeptide with effects on metabolism; however, little is known about its effect on hepatic steatosis and lipid metabolism. METHODS: The serum PRL levels of 456 non-alcoholic fatty liver disease (NAFLD) patients and 403 non-NAFLD controls diagnosed by ultrasound, and 85 subjects with liver histology obtained during metabolic surgery (44 female and 30 male NAFLD patients and 11 age-matched non-NAFLD female subjects) were evaluated...
February 13, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29451774/organic-semiconducting-photoacoustic-nanodroplets-for-laser-activatable-ultrasound-imaging-and-combinational-cancer-therapy
#8
Wei Tang, Zhen Yang, Sheng Wang, Zhantong Wang, Jibin Song, Guocan Yu, Wenpei Fan, Yunlu Dai, Jingjing Wang, Lingling Shan, Gang Niu, Quli Fan, Xiaoyuan Chen
Combination of photoacoustic (PA) and ultrasound (US) imaging offers high spatial resolution images with deep tissue penetration, which shows great potentials in applications in medical imaging. Development of PA/US dual-contrast agents with high contrast and excellent biocompatible is of great interest. Herein, an organic semiconducting photoacoustic nanodroplet, PS-PDI-PAnD, is developed by stabilizing low-boiling-point perfluorocarbon (PFC) droplet with a photoabsorber and photoacoustic agent of perylene diimide (PDI) molecules and co-encapsulating the droplet with photosensitizers of ZnF16Pc molecules...
February 16, 2018: ACS Nano
https://www.readbyqxmd.com/read/29450905/a-tramp-derived-orthotopic-prostate-syngeneic-tops-cancer-model-for-investigating-anti-tumor-treatments
#9
Justin Lardizabal, Jun Ding, Zahid Delwar, Paul S Rennie, William Jia
BACKGROUND: Patients with advanced prostate cancer have limited curative options, therefore new treatments are needed. Mouse models play a pivotal role in the discovery and development of new treatments. In the present study, a TRAMP-derived Orthotopic Prostate Syngeneic (TOPS) mouse model was developed and found to provide a consistent means of monitoring tumor and metastatic responses to novel treatments. METHODS: The mouse TOPS model was generated using luciferase transduced TRAMP-C2 prostate cancer cells that were orthotopically injected into Bl6 mice by ultrasound guidance...
February 16, 2018: Prostate
https://www.readbyqxmd.com/read/29450853/endometriosis-clinical-features-mr-imaging-findings-and-pathologic-correlation
#10
REVIEW
Pietro Valerio Foti, Renato Farina, Stefano Palmucci, Ilenia Anna Agata Vizzini, Norma Libertini, Maria Coronella, Saveria Spadola, Rosario Caltabiano, Marco Iraci, Antonio Basile, Pietro Milone, Antonio Cianci, Giovanni Carlo Ettorre
OBJECTIVE: We illustrate the magnetic resonance imaging (MRI) features of endometriosis. BACKGROUND: Endometriosis is a chronic gynaecological condition affecting women of reproductive age and may cause pelvic pain and infertility. It is characterized by the growth of functional ectopic endometrial glands and stroma outside the uterus and includes three different manifestations: ovarian endometriomas, peritoneal implants, deep pelvic endometriosis. The primary locations are in the pelvis; extrapelvic endometriosis may rarely occur...
February 15, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29449656/ultrasound-beam-steering-of-oxygen-nanobubbles-for-enhanced-bladder-cancer-therapy
#11
Pushpak Bhandari, Gloriia Novikova, Craig J Goergen, Joseph Irudayaraj
New intravesical treatment approaches for bladder cancer are needed as currently approved treatments show several side effects and high tumor recurrence rate. Our study used MB49 murine urothelial carcinoma model to evaluate oxygen encapsulated cellulosic nanobubbles as a novel agent for imaging and ultrasound guided drug delivery. In this study, we show that oxygen nanobubbles (ONB) can be propelled (up to 40 mm/s) and precisely guided in vivo to the tumor by an ultrasound beam. Nanobubble velocity can be controlled by altering the power of the ultrasound Doppler beam, while nanobubble direction can be adjusted to different desired angles by altering the angle of the beam...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29449196/clinical-predictors-of-successful-vaginal-myomectomy-for-prolapsed-pedunculated-uterine-leiomyoma
#12
Serdar Aydın, Hale Göksever Çelik, Mustafa Maraşlı, Rabia Zehra Bakar
OBJECTIVE: Uterine leiomyomas are the most common pelvic tumor in women. The calculated prevalence of prolapsed pedunculated leiomyoma was 2.5% in patients who underwent surgery. Although vaginal removal is safe and effective, hysterectomy demand is questionable. We aimed to analyze the association between patient characteristics, clinical features of prolapsed pedunculated submucosal leiomyoma and the probability of successful vaginal myomectomy. MATERIALS AND METHODS: This study was conducted in 35 women who presented with prolapsed pedunculated uterine leiomyoma...
February 1, 2018: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/29447964/botulinum-toxin-type-a-relieves-sternocleidomastoid-muscle-fibrosis-in-congenital-muscular-torticollis
#13
Banghong Jiang, Wenxuan Zu, Jing Xu, Zhuyou Xiong, Yichao Zhang, Song Gao, Shuxing Ge, Li Zhang
Congenital muscular torticollis (CMT) is a neck deformity that involves shortening of sternocleidomastoid muscle (SCM) characterized by muscle atrophy and interstitial fibrosis. To investigate wheatear Botulinum toxin type A (BTA) has anti-fibrotic effects in CMT, we established acquired muscular torticollis that mimetics CMT in rabbit by intra-SCM injection of anhydrous alcohol. The treatment groups received BTA (2.5 units or 5 units) injection into the fibrotic SCM. The shortening and thickening of SCM were recorded by B-mode ultrasound...
February 12, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29447724/no-127-the-evaluation-of-stress-incontinence-prior-to-primary-surgery
#14
Scott A Farrell
OBJECTIVE: To provide clinical guidelines for the evaluation of women with stress urinary incontinence prior to primary anti-incontinence surgery. OPTIONS: The modalities of evaluation range from basic pelvic examination through to the use of adjuncts including ultrasound and urodynamic testing. OUTCOMES: These guidelines provide a comprehensive approach to the preoperative evaluation of urinary incontinence to ensure that excessive evaluation is avoided without sacrificing diagnostic accuracy...
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29447247/differences-between-fellow-eyes-of-acute-and-chronic-primary-angle-closure-glaucoma-an-ultrasound-biomicroscopy-quantitative-study
#15
Mengwei Li, Yuhong Chen, Xiaoxiao Chen, Wenqing Zhu, Xueli Chen, Xiaolei Wang, Yuan Fang, Xiangmei Kong, Yi Dai, Junyi Chen, Xinghuai Sun
PURPOSE: To compare various biometric parameters between fellow eyes of acute primary angle closure (glaucoma) [APAC(G)] and fellow eyes of chronic primary angle closure (glaucoma) [CPAC(G)]. METHODS: Ultrasound biomicroscopy examinations were performed on 47 patients with unilateral APAC(G) and 41 patients with asymmetric CPAC(G) before laser peripheral iridotomy and pilocarpine treatment. Anterior chamber depth and width (ACD and ACW), lens vault (LV), iris curvature (IC), iris root distance (IRD), trabecular-ciliary process distance (TCPD), iris-ciliary process distance (ICPD), trabecular-ciliary angle (TCA), and other biometric parameters were compared between fellow eyes of APAC(G) and fellow eyes of CAPC(G)...
2018: PloS One
https://www.readbyqxmd.com/read/29447020/effect-of-pretreatment-with-gonadotropin-releasing-hormone-analog-gnrh-%C3%AE-on-high-intensity-focused-ultrasound-ablation-for-diffuse-adenomyosis-a-preliminary-study
#16
Xiao-Ying Zhang, Ying-Shu Guo, Jiu-Mei Chen, Jin-Juan Wang, Hong Ye, Chun-Yi Zang, Hua Duan
OBJECTIVES: To evaluate the efficacy and safety of GnRH-α pretreatment with HIFU ablation for diffuse adenomyosis. METHODS: From January 2014 to December 2016, 61 patients were divided into two groups. Twenty-three patients with larger uteri received pretreatment with GnRH-αand were then subjected to HIFU, and 38 patients underwent HIFU alone. The technical parameters included treatment time, sonication time, average sonication power, treatment intensity, total energy, non-perfusion volume (NPV) and NPV ratio...
February 15, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29446827/effect-of-ultrasound-dielectric-pretreatment-on-the-oxidation-resistance-of-vacuum-fried-apple-chips
#17
Xu Shen, Min Zhang, Bhesh Bhandari, Zhimei Guo
BACKGROUND: In order to investigate ultrasound dielectric pretreatment effect on oxidation resistance of vacuum fried apple chips, apple slices were pretreated at ultrasonic power for 150, 250 and 400 W and time for 10, 20 and, 30 min, followed by vacuum frying (VF) . The quality and oxidation resistance of fried apple were evaluated by testing the dielectric properties and comparing moisture content, oil uptake, color, acid value (AV) and peroxide value (PV) of apple chips. RESULTS: Ultrasonic treatment can significantly change dielectric properties of apple slices...
February 15, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29446324/hepatocellular-carcinoma-surveillance-with-ultrasound-cost-effectiveness-high-risk-populations-uptake
#18
Maxime Ronot, Romain Pommier, Marco Dioguardi Burgio, Yvonne Purcell, Pierre Nahon, Valérie Vilgrain
Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer and the second cause of cancer-related deaths worldwide. In most cases, it is diagnosed in patients with identified risk factors, mainly cirrhosis from all causes. These patients are candidates for a surveillance program that, depending on guidelines, involves regular liver ultrasound alone or combined with serum markers. These programs have been shown to improve the oncological outcome by detecting earlier stage tumors and providing patients with potentially curative treatment and improved survival...
February 15, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29444709/mucinous-cystic-neoplasm-of-the-liver-with-extrahepatic-growth-presenting-with-ascending-cholangitis-diagnosed-by-endoscopic-ultrasound-features-a-case-report
#19
Tanawat Pattarapuntakul, Bancha Ovartlarnporn, Jaksin Sottisuporn
BACKGROUND: Mucinous cystic neoplasm of the liver with extrahepatic growth is a rare benign epithelial neoplasm of the biliary system that presents with a mass effect or is incidentally found on imaging. The tumor affects mostly the common hepatic duct, which is difficult to diagnose preoperatively by radiology, endoscopy, or cystic fluid analysis. Endoscopic ultrasound is a noninvasive tool for the evaluation of features of a cystic lesion and the extent of disease. Optimal treatment is complete tumor resection...
February 15, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29443386/technical-note-error-metrics-for-estimating-the-accuracy-of-needle-instrument-placement-during-transperineal-mr-us-guided-prostate-interventions
#20
Ester Bonmati, Yipeng Hu, Barbara Villarini, Rachael Rodell, Paul Martin, Lianghao Han, Ian Donaldson, Hashim U Ahmed, Caroline M Moore, Mark Emberton, Dean C Barratt
PURPOSE: Image-guided systems that fuse magnetic resonance imaging (MRI) with three-dimensional (3D) ultrasound (US) images for performing targeted prostate needle biopsy and minimally-invasive treatments for prostate cancer are of increasing clinical interest. To date, a wide range of different accuracy estimation procedures and error metrics have been reported, which makes comparing the performance of different systems difficult. METHODS: A set of 9 measures are presented to assess the accuracy of MRI-US image registration, needle positioning, needle guidance, and overall system error, with the aim of providing a methodology for estimating the accuracy of instrument placement using a MR/US-guided transperineal approach...
February 14, 2018: Medical Physics
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