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https://www.readbyqxmd.com/read/29327397/translating-international-hiv-treatment-guidelines-into-local-priorities-in-indonesia
#1
Noor Tromp, Rozar Prawiranegara, Adiatma Siregar, Rudi Wisaksana, Lucas Pinxten, Juul Pinxten, Arry Lesmana Putra, Deni Sunjaya Lesmana, Maarten Jansen, Jan Hontelez, Scott Maurits, Febrina Maharani, Leon Bijlmakers, Rob Baltussen
OBJECTIVE: International guidelines recommend countries to expand Antiretroviral therapy (ART) to all HIV-infected individuals and establish local-level priorities in relation to other treatment, prevention and mitigation interventions through fair processes. However, no practical guidance is provided for such priority setting processes. Evidence-informed deliberative processes (EDPs) fill this gap and combine stakeholder deliberation to incorporate relevant social values with rational decision-making informed by evidence on these values...
January 12, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29325081/dissatisfaction-with-current-integration-reforms-of-health-insurance-schemes-in-china-are-they-a-success-and-what-matters
#2
Linghan Shan, Miaomiao Zhao, Ning Ning, Yanhua Hao, Ye Li, Libo Liang, Zheng Kang, Hong Sun, Ding Ding, Baohua Liu, Chao Liang, Miao Yu, Qunhong Wu, Mo Hao, Hua Fan
Integration reforms have been piloted as key policies to address the fragmented health insurance system in China. They are also regarded as a better choice for realizing a Universal Basic Medical Insurance System (UBMIS). This study has attempted to explore the determinants that may affect respondents' dissatisfaction with the reforms. The aim is to provide evidence for more effective policy adjustment during the next round of nationwide integration reforms in China. A cross-sectional questionnaire survey was conducted in Ningbo, Chongqing and Heilongjiang from 2014 to 2015...
January 6, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29300680/utilization-pattern-of-haemophilus-influenza-type-b-vaccine-in-eight-provinces-of-china
#3
Yan Li, Chenyan Yue, Yamin Wang, Xu Zhu, Kathryn Martin, Robert W Scherpbier, Jiechen Liu, Zhiguo Wang, Yujie Ma, Huijian Cheng, Zhenguo Zhang, Qing Wang, Hui Li, Shen Xie, Qiyou Xiao, Huaqing Wang, Zhijie An
Objective In China, Hib vaccine is a private-sector vaccine that is an option for parents to select to give to their children; it must be paid for out-of-pocket because it is not included in the government's Expanded Program on Immunization (EPI). We evaluated utilization patterns of Hib vaccine to provide evidence in support of development of a national Hib vaccination strategy. Methods We obtained lists of children from immunization information systems (IIS) of counties or districts in 8 provinces of China that had IISs that recorded Hib vaccine administration continuously for the study period...
January 4, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29281865/cancer-screening-awareness-and-practice-in-a-middle-income-country-a-systematic-review-from-ira
#4
Azam Majidi, Somayye Majidi, Somayye Salimzadeh, Maryam Khazaee- Pool, Alireza Sadjadi, Hamideh Salimzadeh, Alireza Delavari
Objective: Ageing population and noticeable changes in lifestyle in developing countries like Iran caused an increase in cancer incidence. This requires organized cancer prevention and screening programs in population level, but most importantly community should be aware of these programs and willing to use them. This study explored existing evidence on public awareness and practice, as well as, adherence to cancer screening in Iranian population. Methods: Major English databases including Web of Science, PubMed, Scopus, and domestic Persian databases i...
December 28, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29276400/challenges-and-unmet-needs-in-basal-insulin-therapy-lessons-from-the-asian-experience
#5
REVIEW
Wing Bun Chan, Jung Fu Chen, Su-Yen Goh, Thi Thanh Huyen Vu, Iris Thiele Isip-Tan, Sony Wibisono Mudjanarko, Shailendra Bajpai, Maria Aileen Mabunay, Pongamorn Bunnag
Basal insulin therapy can improve glycemic control in people with type 2 diabetes. However, timely initiation, optimal titration, and proper adherence to prescribed basal insulin regimens are necessary to achieve optimal glycemic control. Even so, glycemic control may remain suboptimal in a significant proportion of patients. Unique circumstances in Asia (eg, limited resources, management of diabetes primarily in nonspecialist settings, and patient populations that are predominantly less educated) coupled with the limitations of current basal insulin options (eg, risk of hypoglycemia and dosing time inflexibility) amplify the challenge of optimal basal insulin therapy in Asia...
2017: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/29273655/politics-policies-and-processes-a-multidisciplinary-and-multimethods-research-programme-on-policies-on-the-social-determinants-of-health-inequity-in-australia
#6
Fran Baum, Sharon Friel
INTRODUCTION: The development and implementation of multisectoral policy to improve health and reduce health inequities has been slow and uneven. Evidence is largely focused on the facts of health inequities rather than understanding the political and policy processes. This 5-year funded programme of research investigates how these processes could function more effectively to improve equitable population health. METHODS AND ANALYSIS: The programme of work is organised in four work packages using four themes (macroeconomics and infrastructure, land use and urban environments, health systems and racism) related to the structural drivers shaping the distribution of power, money and resources and daily living conditions...
December 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/29258542/radiotherapy-of-mri-detected-involved-internal-mammary-lymph-nodes-in-breast-cancer
#7
Sean Sachdev, Chelain R Goodman, Erin Neuschler, Kapila Kalakota, Daniel Cutright, Eric D Donnelly, John P Hayes, Adam E Prescott, Gianna Mirabelli, Jonathan B Strauss
BACKGROUND: The internal mammary (IM) lymph node chain, along with the axillary nodal basin, is a first-echelon breast lymphatic draining site. A growing body of evidence supports irradiation of this region in node-positive breast cancer. This study evaluated the effectiveness of radiotherapy in treating magnetic resonance imaging (MRI)-detected abnormal IM lymph nodes in newly-diagnosed non-metastatic breast cancer. METHODS: A structured query was performed on an electronic institutional database to identify women with radiographic evidence of abnormal IM node(s) on breast MRI from 2005 to 2013...
December 19, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/29250816/bartlett-type-corrections-and-bootstrap-adjustments-of-likelihood-based-inference-methods-for-network-meta-analysis
#8
Hisashi Noma, Kengo Nagashima, Kazushi Maruo, Masahiko Gosho, Toshi A Furukawa
In network meta-analyses that synthesize direct and indirect comparison evidence concerning multiple treatments, multivariate random effects models have been routinely used for addressing between-studies heterogeneities. Although their standard inference methods depend on large sample approximations (eg, restricted maximum likelihood estimation) for the number of trials synthesized, the numbers of trials are often moderate or small. In these situations, standard estimators cannot be expected to behave in accordance with asymptotic theory; in particular, confidence intervals cannot be assumed to exhibit their nominal coverage probabilities (also, the type I error probabilities of the corresponding tests cannot be retained)...
December 18, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/29237503/integration-of-eye-health-into-primary-care-services-in-tanzania-a-qualitative-investigation-of-experiences-in-two-districts
#9
Emma Jolley, Milka Mafwiri, Joanna Hunter, Elena Schmidt
BACKGROUND: Visual impairment is a public health problem in sub-Saharan Africa, affecting nearly 5% of the population. Efforts to combat avoidable causes have been hampered by weak health systems and little evidence exists to suggest what interventions may be effective to improve the situation. Despite this, there are calls to promote some specific interventions, one of which being the closer integration of eye health services into health systems, often focusing on training primary health workers to deliver basic eye health services...
December 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29232277/scaling-up-hiv-self-testing-in-sub-saharan-africa-a-review-of-technology-policy-and-evidence
#10
Pitchaya P Indravudh, Augustine T Choko, Elizabeth L Corbett
PURPOSE OF REVIEW: HIV self-testing (HIVST) can provide complementary coverage to existing HIV testing services and improve knowledge of status among HIV-infected individuals. This review summarizes the current technology, policy and evidence landscape in sub-Saharan Africa and priorities within a rapidly evolving field. RECENT FINDINGS: HIVST is moving towards scaled implementation, with the release of WHO guidelines, WHO prequalification of the first HIVST product, price reductions of HIVST products and a growing product pipeline...
December 9, 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/29227842/ideation-social-construction-and-drug-policy-a-scoping-review
#11
Vanessa Gstrein
Within drug policy scholarship there is a growing body of literature applying ideational and social constructionist approaches to address the complexity of drug policy making and the apparent failure of the evidence-based policy paradigm to free the process from controversy and contestation. Ideational approaches are concerned with the roles played by ideas and beliefs in policy making, while social construction explores the way policy problems are constructed, and agendas are set and delineated by dominant frames and narratives...
December 8, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29223847/funding-breakthrough-therapies-a-systematic-review-and-recommendation
#12
REVIEW
E Hanna, M Toumi, C Dussart, B Borissov, O Dabbous, K Badora, P Auquier
BACKGROUND: Advanced therapy medicinal products (ATMPs) are innovative therapies likely associated with high prices. Payers need guidance to create a balance between ensuring patient access to breakthrough therapies and maintaining the financial sustainability of the healthcare system. OBJECTIVE: The aims of this study were to identify, define, classify and compare the approaches to funding high-cost medicines proposed in the literature, to analyze their appropriateness for ATMP funding and to suggest an optimal funding model for ATMPs...
December 2, 2017: Health Policy
https://www.readbyqxmd.com/read/29223134/rapid-soil-formation-after-glacial-retreat-shaped-by-spatial-patterns-of-organic-matter-accrual-in-microaggregates
#13
Steffen A Schweizer, Carmen Hoeschen, Steffen Schlüter, Ingrid Kögel-Knabner, Carsten W Mueller
Global change contributes to the retreat of glaciers at unprecedented rates. The deglaciation facilitates biogeochemical processes on glacial deposits with initiating soil formation as an important driver of evolving ecosystems. The underlying mechanisms of soil formation and the association of soil organic matter (SOM) with mineral particles remain unclear, although further insights are critical to understand carbon sequestration in soils. We investigated the microspatial arrangement of SOM coatings at intact soil microaggregate structures during various stages of ecosystem development from 15 to >700 years after deglaciation in the proglacial environment of the Damma glacier (Switzerland)...
December 9, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29220188/instability-mechanisms-of-water-in-oil-nanoemulsions-with-phospholipids-temporal-and-morphological-structures
#14
Jan-Hendrik Sommerling, Maria Betania Carreira de Matos, Ellen Hildebrandt, Alberto Dessy, Robbert J Kok, Hermann Nirschl, Gero Leneweit
Many food preparations, pharmaceuticals, and cosmetics use water in oil (W/O) emulsions stabilized by phospholipids. Moreover, recent technological developments try to produce liposomes or lipid coated capsules from W/O emulsions, but are faced with colloidal instabilities. To explore these instability mechanisms, emulsification by sonication was applied in three cycles and the sample stability was studied for 3 hours after each cycle. Clearly identifiable temporal structures of instability provide evidence about the emulsion morphology: an initial regime of about 10 minutes is shown to be governed by coalescence after which Ostwald ripening dominates...
December 8, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29212501/equity-implications-for-sanitation-from-recent-health-and-nutrition-evidence
#15
EDITORIAL
A A Cronin, M E Gnilo, M Odagiri, S Wijesekera
Recent evidence points to the possible underestimation of the health and nutrition impact of sanitation. Community sanitation coverage may first need to reach thresholds in the order of 60% or higher, to optimize health and nutrition gains. Increasing coverage of sanitation to levels below 60% of community coverage may not result in substantial gains. For example, moving Indonesia from 60% to 100% improved sanitation coverage could significantly reduce diarrhoea in children under 5 years old (by an estimated 24% reduction in odds ratio for child diarrhoea morbidity) with gains split equally by reaching underserved communities and the unserved within communities...
December 6, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29210333/training-reproductive-health-professionals-in-a-post-conflict-environment-exploring-medical-nursing-and-midwifery-education-in-mogadishu-somalia
#16
Abdiasis Yalahow, Mariam Hassan, Angel M Foster
Following two decades of civil war, Somalia recently entered the post-conflict rebuilding phase that has resulted in the rapid proliferation of higher education institutions. Given the high maternal mortality ratio, the federal government has identified the reproductive health education of health service professionals as a priority. Yet little is known about the coverage of contraception, abortion, pregnancy, childbirth, and sexual and gender-based violence (SGBV) in medicine, nursing, or midwifery. In 2016, we conducted a multi-methods study to understand the reproductive health education and training landscape and identify avenues by which development of the next generation of health service professionals could be improved...
December 6, 2017: Reproductive Health Matters
https://www.readbyqxmd.com/read/29202093/health-status-and-health-systems-financing-in-the-mena-region-roadmap-to-universal-health-coverage
#17
Eyob Zere Asbu, Maysoun Dimachkie Masri, Amer Kaissi
Background: Since the declaration of the Millennium Development Goals (MDGs) in 1990, many countries of the Middle East and North Africa (MENA) region made some improvements in maternal and child health and in tackling communicable diseases. The transition to the global agenda of Sustainable Development Goals brings new opportunities for countries to move forward toward achieving progress for better health, well-being, and universal health coverage. This study provides a profile of health status and health financing approaches in the MENA region and their implications on universal health coverage...
2017: Global Health Research and Policy
https://www.readbyqxmd.com/read/29194440/attacking-the-mosquito-on-multiple-fronts-insights-from-the-vector-control-optimization-model-vcom-for-malaria-elimination
#18
Samson S Kiware, Nakul Chitnis, Allison Tatarsky, Sean Wu, Héctor Manuel Sánchez Castellanos, Roly Gosling, David Smith, John M Marshall
BACKGROUND: Despite great achievements by insecticide-treated nets (ITNs) and indoor residual spraying (IRS) in reducing malaria transmission, it is unlikely these tools will be sufficient to eliminate malaria transmission on their own in many settings today. Fortunately, field experiments indicate that there are many promising vector control interventions that can be used to complement ITNs and/or IRS by targeting a wide range of biological and environmental mosquito resources. The majority of these experiments were performed to test a single vector control intervention in isolation; however, there is growing evidence and consensus that effective vector control with the goal of malaria elimination will require a combination of interventions...
2017: PloS One
https://www.readbyqxmd.com/read/29190374/scaling-up-newborn-care-in-afghanistan-opportunities-and-challenges-for-the-health-sector
#19
Malalai Naziri, Ariel Higgins-Steele, Zelaikha Anwari, Khaksar Yousufi, Karla Fossand, Sher Shah Amin, David B Hipgrave, Sherin Varkey
Newborn health in Afghanistan is receiving increased attention, but reduction in newborn deaths there has not kept pace with declines in maternal and child mortality. Using the continuum of care and health systems building block frameworks, this article identifies, organizes and provides a synthesis of the available evidence on and gaps in coverage of care and health systems, programmes, policies and practices related to newborn health in Afghanistan. Newborn mortality in Afghanistan is related to the nation's weak health system, itself associated with decades of conflict, low and uneven coverage of essential interventions, demand-side and cultural specificities, and compromised quality...
November 27, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29181549/treating-open-lower-limb-fractures-successfully-thoughts-and-current-practice-on-therapy-and-centralization-in-the-netherlands
#20
K Oflazoglu, J M Hoogendoorn, P van der Zwaal, E T Walbeehm, W A van Enst, H R Holtslag, D Hofstee, P Plantinga, M Elzinga, H Rakhorst
INTRODUCTION: The British Orthopedic Association (BOA) and British Association of Plastic, Reconstructive and Aesthetic Surgeons (BAPRAS) updated the evidence-based guidelines for the treatment and care of open lower limb fractures (BOAST 4). Following this, a Dutch version has been developed. The main points are multidisciplinary care, planning, and treatment of these injuries. Early osteosynthesis (within 7-14 days) combined with soft-tissue coverage results in more efficient care and less complications...
November 27, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
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