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https://www.readbyqxmd.com/read/28816556/maternal-mortality-in-the-last-triennium-of-the-millennium-development-goal-era-at-the-obafemi-awolowo-university-teaching-hospitals-complex-ile-ife-nigeria
#1
Ibraheem Olayemi Awowole, Olusegun Olalekan Badejoko, Oluwafemi Kuti, Omotade Adebimpe Ijarotimi, Oluwaseun Oludotun Sowemimo, Ifeoluwa Emmanuel Ogunduyile
The maternal mortality ratio (MMR) of Nigeria remains high. This retrospective study aims to suggest evidence-based strategies towards achieving the sustainable development goal target 3.1 at the Obafemi Awolowo University Teaching Hospital (OAUTHC), Nigeria by providing contemporary data on MMR between October 2012 and September 2015. There were 86 maternal deaths and 5243 live births over the triennium, with annual MMRs of 1744, 1622 and 1512/100,000 live births, respectively. Fifty-six (65.2%) were postpartum deaths, while 44 (51...
August 17, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28812807/health-technology-assessment-global-advocacy-and-local-realities-comment-on-priority-setting-for-universal-health-coverage-we-need-evidence-informed-deliberative-processes-not-just-more-evidence-on-cost-effectiveness
#2
Kalipso Chalkidou, Ryan Li, Anthony J Culyer, Amanda Glassman, Karen J Hofman, Yot Teerawattananon
Cost-effectiveness analysis (CEA) can help countries attain and sustain universal health coverage (UHC), as long as it is context-specific and considered within deliberative processes at the country level. Institutionalising robust deliberative processes requires significant time and resources, however, and countries often begin by demanding evidence (including local CEA evidence as well as evidence about local values), whilst striving to strengthen the governance structures and technical capacities with which to generate, consider and act on such evidence...
August 29, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28807608/benefits-of-flu-vaccination-for-persons-with-diabetes-mellitus-a-review
#3
REVIEW
M Goeijenbier, T T van Sloten, L Slobbe, C Mathieu, P van Genderen, Walter E P Beyer, Albert D M E Osterhaus
Diabetes mellitus imposes a significant and increasing burden on society, with major consequences for human health, welfare and the economy worldwide. Persons with diabetes mellitus are at increased risk of developing severe complications after influenza virus infection and guidelines advise vaccination. The present evidence for influenza vaccine effectiveness in persons with diabetes mellitus is mainly based on observational studies with clinical endpoints like hospitalization and death, indicating a beneficial reduction of morbidity and mortality...
August 11, 2017: Vaccine
https://www.readbyqxmd.com/read/28789627/using-lot-quality-assurance-sampling-to-assess-access-to-water-sanitation-and-hygiene-services-in-a-refugee-camp-setting-in-south-sudan-a-feasibility-study
#4
Elizabeth Harding, Colin Beckworth, Jean-Francois Fesselet, Annick Lenglet, Richard Lako, Joseph J Valadez
BACKGROUND: Humanitarian agencies working in refugee camp settings require rapid assessment methods to measure the needs of the populations they serve. Due to the high level of dependency of refugees, agencies need to carry out these assessments. Lot Quality Assurance Sampling (LQAS) is a method commonly used in development settings to assess populations living in a project catchment area to identify their greatest needs. LQAS could be well suited to serve the needs of refugee populations, but it has rarely been used in humanitarian settings...
August 8, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28782240/electrophoretic-deposition-of-mgo-nanoparticles-imparts-antibacterial-properties-to-poly-l-lactic-acid-for-orthopedic-applications
#5
Daniel J Hickey, Divya Muthusamy, Thomas J Webster
Bacterial infection of implanted biomaterials is a serious problem that increases health care costs and negatively affects a considerable fraction of orthopedic procedures. In this field, magnesium oxide nanoparticles (MgO NPs) have emerged as a promising material to combat bacterial infection while maintaining or improving bone cell functions. Here, MgO NPs were electrophoretically deposited onto poly-L-lactic acid (PLLA) sheets to achieve a coating of highly exposed MgO NPs that directly influenced cell-substrate interactions at short time scales...
August 7, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28780541/associations-between-highly-active-antiretroviral-therapy-and-the-presence-of-hpv-premalignant-and-malignant-cervical-lesions-in-sub-saharan-africa-a-systematic-review-current-evidence-and-directions-for-future-research
#6
Sonia Menon, Rodolfo Rossi, Natasha Zdraveska, Mbabazi Kariisa, Sushama D Acharya, Davy Vanden Broeck, Steven Callens
OBJECTIVES: In sub-Saharan Africa, substantial international funding along with evidence-based clinical practice have resulted in an unparalleled scale-up of access to antiretroviral treatment at a higher CD4 count. The role and timing of highly active antiretroviral therapy (HAART) in mediating cervical disease remains unclear. The aim of this article is to systematically review all evidence pertaining to Africa and identify research gaps regarding the epidemiological association between HAART use and the presence of premalignant/malignant cervical lesions...
August 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28775196/systematic-review-and-meta-analysis-of-infant-and-young-child-feeding-practices-enat-p-in-ethiopia-protocol
#7
Tesfa Dejenie Habtewold, Md Atiqul Islam, Nigussie Tadesse Sharew, Shimels Hussien Mohammed, Mulugeta Molla Birhanu, Balewgizie Sileshi Tegegne
INTRODUCTION: Infant and young child feeding (IYCF) is the cornerstone of infant and child survival, healthy growth and development, healthy future generations and national development. In spite of the importance of optimal nutrition in low- and middle-income countries, there has been no review conducted in Ethiopia. Thus, the aim of this systematic review and meta-analysis is to estimate the national coverage and identify the associated factors of IYCF practices in Ethiopia. METHODS: PubMed, Scopus, EMBASE, CINHAL, EBSCO, Web of Science and WHO Global Health Library databases will be searched for all available publications from 1 January 2000 to 30 September 2017...
August 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28773891/flow-chamber-system-for-the-statistical-evaluation-of-bacterial-colonization-on-materials
#8
Friederike Menzel, Bianca Conradi, Karsten Rodenacker, Anna A Gorbushina, Karin Schwibbert
Biofilm formation on materials leads to high costs in industrial processes, as well as in medical applications. This fact has stimulated interest in the development of new materials with improved surfaces to reduce bacterial colonization. Standardized tests relying on statistical evidence are indispensable to evaluate the quality and safety of these new materials. We describe here a flow chamber system for biofilm cultivation under controlled conditions with a total capacity for testing up to 32 samples in parallel...
September 10, 2016: Materials
https://www.readbyqxmd.com/read/28770599/effect-of-frequency-of-clinic-visits-and-medication-pick-up-on-antiretroviral-treatment-outcomes-a-systematic-literature-review-and-meta-analysis
#9
Tsitsi Mutasa-Apollo, Nathan Ford, Matthew Wiens, Maria Eugenia Socias, Eyerusalem Negussie, Ping Wu, Evan Popoff, Jay Park, Edward J Mills, Steve Kanters
INTRODUCTION: Expanding and sustaining antiretroviral therapy (ART) coverage may require simplified HIV service delivery strategies that concomitantly reduce the burden of care on the health system and patients while ensuring optimal outcomes. We conducted a systematic review to assess the impact of reduced frequency of clinic visits and drug dispensing on patient outcomes. METHODS: As part of the development process of the World Health Organization antiretroviral (ARV) guidelines, we systematically searched medical literature databases for publications up to 30 August 2016...
July 21, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28757447/the-phylogeny-of-extant-starfish-asteroidea-echinodermata-including-xyloplax-based-on-comparative-transcriptomics
#10
Gregorio V Linchangco, David W Foltz, Rob Reid, John Williams, Conor Nodzak, Alexander M Kerr, Allison K Miller, Rebecca Hunter, Nerida G Wilson, William J Nielsen, Christopher L Mah, Greg W Rouse, Gregory A Wray, Daniel A Janies
Multi-locus phylogenetic studies of echinoderms based on Sanger and RNA-seq technologies and the fossil record have provided evidence for the Asterozoa-Echinozoa hypothesis. This hypothesis posits a sister relationship between asterozoan classes (Asteroidea and Ophiuroidea) and a similar relationship between echinozoan classes (Echinoidea and Holothuroidea). Despite this consensus around Asterozoa-Echinozoa, phylogenetic relationships within the class Asteroidea (sea stars or starfish) have been controversial for over a century...
July 27, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28755543/assessing-income-redistributive-effect-of-health-financing-in-zambia
#11
Arnold Mulenga, John Ele-Ojo Ataguba
Ensuring an equitable health financing system is a major concern particularly in many developing countries. Internationally, there is a strong debate to move away from excessive reliance on direct out-of-pocket (OOP) spending towards a system that incorporates a greater element of risk pooling and thus affords greater protection for the poor. This is a major focus of the move towards universal health coverage (UHC). Currently, Zambia with high levels of poverty and income inequality is implementing health sector reforms for UHC through a social health insurance scheme...
July 21, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28755227/development-of-sex-specific-pcr-based-markers-in-date-palm
#12
Mohamed A M Atia, Mahmoud M Sakr, Morad M Mokhtar, Sami S Adawy
Molecular markers are used efficiently in the development and identification of gender-specific PCR-based markers in date palm. There is mounting evidence that different marker systems vary in their mechanisms of detecting polymorphism and genome coverage. Therefore, they could complement each other to generate accurate sex-specific markers in date palm. This chapter describes the uses of PCR-based molecular markers to develop and identify the gender in different date palm genotypes; these are amplified fragment length polymorphism (AFLP), start codon targeted polymorphism (SCoT), conserved DNA-derived polymorphism (CDDP), intron-targeted amplified polymorphism (ITAP), and random amplified polymorphic DNA (RAPD)...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28754651/a-smartphone-app-for-adolescents-with-sleep-disturbance-development-of-the-sleep-ninja
#13
Aliza Werner-Seidler, Bridianne O'Dea, Fiona Shand, Lara Johnston, Anna Frayne, Andrea S Fogarty, Helen Christensen
BACKGROUND: Sleep disturbances are common in young people and have consequences for academic, social, emotional, and behavioral development. The most effective treatment is cognitive behavioral therapy for insomnia (CBT-I), with evidence suggesting that it is efficacious even when delivered digitally. OBJECTIVE: There are no commercially available digitally delivered CBT-I programs for use by young people. The aim of this project was to develop a smartphone app that delivers CBT-I to young people to improve sleep...
July 28, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28743592/piloting-water-quality-testing-coupled-with-a-national-socioeconomic-survey-in-yogyakarta-province-indonesia-towards-tracking-of-sustainable-development-goal-6
#14
Aidan A Cronin, Mitsunori Odagiri, Bheta Arsyad, Mariet Tetty Nuryetty, Gantjang Amannullah, Hari Santoso, Kristin Darundiyah, Nur 'Aisyah Nasution
There remains a pressing need for systematic water quality monitoring strategies to assess drinking water safety and to track progress towards the Sustainable Development Goals (SDG). This study incorporated water quality testing into an existing national socioeconomic survey in Yogyakarta province, Indonesia; the first such study in Indonesia in terms of SDG tracking. Multivariate regression analysis assessed the association between faecal and nitrate contamination and drinking water sources household drinking water adjusted for wealth, education level, type of water sources and type of sanitation facilities...
July 15, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28737994/impact-of-a-patient-support-program-on-patient-adherence-to-adalimumab-and-direct-medical-costs-in-crohn-s-disease-ulcerative-colitis-rheumatoid-arthritis-psoriasis-psoriatic-arthritis-and-ankylosing-spondylitis
#15
David T Rubin, Manish Mittal, Matthew Davis, Scott Johnson, Jingdong Chao, Martha Skup
BACKGROUND: AbbVie provides a free-to-patient patient support program (PSP) to assist adalimumab-treated patients with medication costs, nurse support, injection training, pen disposal, and medication reminders. The impact of these services on patient adherence to adalimumab and direct medical costs associated with autoimmune disease has not been assessed. OBJECTIVE: To quantify the relationship between participation in a PSP and outcomes (adalimumab adherence, persistence, and direct medical costs) in patients initiating adalimumab treatment...
August 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28736716/mucositis-and-oral-infections-secondary-to-gram-negative-rods-in-patients-with-prolonged-neutropenia
#16
Mindy M Sampson, Sowmya Nanjappa, John N Greene
Patients with prolonged neutropenia are at risk for a variety of complications and infections including the development of mucositis and oral ulcers. The changes in oral flora during chemotherapy and its effects on the development of infections of the oral cavity have been studied with inconsistent results. However, there is evidence that supports the colonization of gram negative rods in patients undergoing chemotherapy. In this report, we present two leukemic patients who developed oral ulcers secondary to multi-drug resistant Pseudomonas aeruginosa...
2017: IDCases
https://www.readbyqxmd.com/read/28734789/weathered-mc252-crude-oil-induced-anemia-and-abnormal-erythroid-morphology-in-double-crested-cormorants-phalacrocorax-auritus-with-light-microscopic-and-ultrastructural-description-of-heinz-bodies
#17
Kendal E Harr, Fred L Cunningham, Chris A Pritsos, Karen L Pritsos, Thivanka Muthumalage, Brian S Dorr, Katherine E Horak, Katie C Hanson-Dorr, Karen M Dean, Dave Cacela, Andrew K McFadden, Jane E Link, Katherine A Healy, Pete Tuttle, Steven J Bursian
Injury assessment of birds following the Deepwater Horizon (DWH) oil spill in 2010 was part of the Natural Resource Damage Assessment. One reported effect was hemolytic anemia with the presence of Heinz bodies (HB) in birds, however, the role of route and magnitude of exposure to oil is unknown. The purpose of the present study was to determine if double-crested cormorants (Phalacocorax auritis; DCCO) exposed orally and dermally to artificially weathered crude oil would develop hemolytic anemia including HB and reticulocytosis...
July 19, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28726280/an-efficient-study-design-to-test-parent-of-origin-effects-in-family-trios
#18
Xiaobo Yu, Gao Chen, Rui Feng
Increasing evidence has shown that genes may cause prenatal, neonatal, and pediatric diseases depending on their parental origins. Statistical models that incorporate parent-of-origin effects (POEs) can improve the power of detecting disease-associated genes and help explain the missing heritability of diseases. In many studies, children have been sequenced for genome-wide association testing. But it may become unaffordable to sequence their parents and evaluate POEs. Motivated by the reality, we proposed a budget-friendly study design of sequencing children and only genotyping their parents through single nucleotide polymorphism array...
July 20, 2017: Genetic Epidemiology
https://www.readbyqxmd.com/read/28707435/evidence-based-policy-choices-for-efficient-and-equitable-cervical-cancer-screening-programs-in-low-resource-settings
#19
Nicole G Campos, Vivien Tsu, Jose Jeronimo, Mercy Mvundura, Jane J Kim
Women in developing countries disproportionately bear the burden of cervical cancer. The availability of prophylactic vaccines against human papillomavirus (HPV) types 16 and 18, which cause approximately 70% of cervical cancers, provides reason for optimism as roll-out begins with support from Gavi, the Vaccine Alliance. However, for the hundreds of millions of women beyond the target age for HPV vaccination, cervical cancer screening to detect and treat precancerous lesions remains the only form of prevention...
August 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28695544/performance-based-risk-sharing-arrangements-an-updated-international-review
#20
REVIEW
Josh J Carlson, Shuxian Chen, Louis P Garrison
Enthusiasm for performance-based risk-sharing arrangements (PBRSAs) continues but at variable pace across countries. Our objective was to identify and characterize publicly available cases and related trends for these arrangements. We performed a review of PBRSAs from 1993 to 2016 using the University of Washington PBRSA Database. Arrangements were categorized according to a previously published taxonomy. Macro-level trends were identified related to the timing of adoption, countries involved, types of arrangements, and disease areas...
July 10, 2017: PharmacoEconomics
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