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https://www.readbyqxmd.com/read/27903026/-severe-hypercapnic-respiratory-failure-in-acute-exacerbation-of-copd-significance-of-ventilation-and-extracorporal-co2-removal
#1
Michael Westhoff, Martin Bachmann, Stephan Braune, Christian Karagiannidis, Stefan Kluge, Philipp M Lepper, Thomas Müller, Bernd Schönhofer
In acute exacerbations of COPD with acute hypercapnic respiratory failure and a pH 7.25 - 7.35, the initiation of non-invasive ventilation is the gold standard. However, absolute and relative contraindications have to be taken into account. The implementation of non-invasive ventilation in case of a severe respiratory acidosis necessitates a skilled therapeutic team and a close monitoring in order to avoid or perceive a NIV failure in time. In this case, the intubation and invasive mechanical ventilation is recommended...
November 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27836209/-extracorporeal-co2-removal-as-life-support-system-for-a-severe-organizing-pneumonia
#2
G Rival, O Millet, G Capellier
INTRODUCTION: Acute lung injuries are usually found in intensive care unit. The diffuse alveolar damage (DAD) is the associated histological pattern and the most severe end-stage of the disease. Organizing pneumonia (OP), for which corticosteroids are the reference therapy, can mimic DAD. While postponing the response to treatment, to limit mechanical ventilation side effects, extracorporeal membrane oxygene can be proposed. We present a case of a severe OP for which extracorporeal CO2 removal (ECCO2R) is used as a bridge to recovery under corticosteroid therapy...
November 8, 2016: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/27562206/role-of-technology-for-the-management-of-aki-in-critically-ill-patients-from-adoptive-technology-to-precision-continuous-renal-replacement-therapy
#3
J Cerdá, I Baldwin, P M Honore, G Villa, John A Kellum, Claudio Ronco
This paper reports on the continuous renal replacement therapy (CRRT) technology group recommendations and research proposals developed during the 17th Acute Dialysis Quality Initiative Meeting in Asiago, Italy. The group was tasked to address questions related to the impact of technology on acute kidney injury management. We discuss technological aspects of the decision to initiate CRRT and the components of the treatment prescription and delivery, the integration of information technology (IT) on overall patient management, the incorporation of CRRT into other 'non-renal' extracorporeal technologies such as ECMO and ECCO2R and the use of sorbents in sepsis and propose new areas for future research...
2016: Blood Purification
https://www.readbyqxmd.com/read/27537725/successful-management-of-acute-respiratory-failure-in-an-idiopathic-pulmonary-fibrosis-patient-using-an-extracorporeal-carbon-dioxide-removal-system
#4
Andrea Vianello, Giovanna Arcaro, Luciana Paladini, Silvia Iovino
Patients with Idiopathic Pulmonary Fibrosis (IPF) requiring Invasive Mechanical Ventilation (IMV) following unsuccessful treatment with Non-Invasive Ventilation (NIV) have a high mortality rate. IMV is, moreover, an independent predictor of poor outcome during the post-transplantation period in patients on waiting lists for Lung Transplantation (LT). Here we describe the successful management of an IPF patient with acute respiratory failure (ARF) using a pump-assisted veno-venous system for extracorporeal CO2 removal (ECCO2R) (ProLUNG® system) as an alternative to endotracheal intubation (ETI) following NIV failure...
2016: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/27465095/single-site-cannulation-veno-venous-extracorporeal-co2-removal-as-bridge-to-lung-volume-reduction-surgery-in-end-stage-lung-emphysema
#5
Bassam Redwan, Stephan Ziegeler, Michael Semik, Joachim Fichter, Nicolas Dickgreber, Volker Vieth, Erik Christian Ernst, Stefan Fischer
Lung volume reduction surgery (LVRS) is an important treatment option for end-stage lung emphysema in carefully selected patients. Here, we first describe the application of low-flow v-v extracorporeal CO2 removal (LFVV-ECCO2R) as bridge to LVRS in patients with end-stage lung emphysema experiencing severe hypercapnia due to acute failure of the breathing pump.Between March and October 2015, n = 4 patients received single-site LFVV-ECCO2R as bridge to LVRS.Indication for ECLS was severe hypercapnia with respiratory acidosis and acute breathing pump failure...
July 26, 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/27456703/the-feasibility-and-safety-of-extracorporeal-carbon-dioxide-removal-to-avoid-intubation-in-patients-with-copd-unresponsive-to-noninvasive-ventilation-for-acute-hypercapnic-respiratory-failure-eclair%C3%A2-study-multicentre-case-control-study
#6
Stephan Braune, Annekatrin Sieweke, Franz Brettner, Thomas Staudinger, Michael Joannidis, Serge Verbrugge, Daniel Frings, Axel Nierhaus, Karl Wegscheider, Stefan Kluge
INTRODUCTION: The aim of the study was to evaluate the feasibility and safety of avoiding invasive mechanical ventilation (IMV) by using extracorporeal CO2 removal (ECCO2R) in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and acute hypercapnic respiratory failure refractory to noninvasive ventilation (NIV). METHODS: Case-control study. Patients with acute hypercapnic respiratory failure refractory to NIV being treated with a pump-driven veno-venous ECCO2R system (iLA-Activve(®); Novalung, Heilbronn, Germany) were prospectively observed in five European intensive care units (ICU)...
September 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27424471/extracorporeal-life-support-as-bridge-to-lung-retransplantation-a-multicenter-pooled-data-analysis
#7
Stéphane Collaud, Christian Benden, Christoph Ganter, Sven Hillinger, Isabelle Opitz, Didier Schneiter, Reto Schuepbach, Ilhan Inci, Walter Weder
BACKGROUND: Extracorporeal life support (ECLS) as a bridge to lung retransplantation has been reported only anecdotally. Thus, we analyzed combined data from our center with pooled data from published studies to identify selection criteria for this advanced therapy. METHODS: Four patients at our center were bridged on ECLS to lung retransplantation. Patient data were retrospectively retrieved from electronic records. The MEDLINE database was searched using the PubMed engine and yielded 13 relevant studies that included a minimum of 3 patients bridged to lung retransplantation, and four studies described detailed data on 17 patients...
July 14, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27290253/ecco2r-a-french-national-survey
#8
B Deniau, J D Ricard, J Messika, D Dreyfuss, S Gaudry
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27290071/in-patients-under-extracorporeal-co2-removal-therapy-ecco2r-for-ards-can-we-do-prone-position-efficiency-stability-and-safety-of-the-maneuver
#9
P Ngasseu, J P Ponthus, V Amilien, M Tchir, J F Georger
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27290064/feasibility-of-the-implementation-of-a-technic-of-extra-corporeal-co2-removal-ecco2r-in-an-intensive-care-unit-which-doesn-t-use-ecmo-and-its-real-utilization
#10
V Amilien, J P Ponthus, P Ngasseu, E Barsam, P Lehericey, M Tchir, E Bezian, J F Georger
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27267600/adverse-effects-of-extracorporeal-carbon-dioxide-removal-ecco2r-for-acute-respiratory-failure-a-systematic-review-protocol
#11
Zulian Liu, Rui V Duarte, Sue Bayliss, George Bramley, Carole Cummins
BACKGROUND: The extracorporeal membrane carbon dioxide removal (ECCO2R) system is primarily designed for the purpose of removing CO2 from the body for patients with potentially reversible severe acute hypercapnic respiratory failure or being considered for lung transplantation. Systematic reviews have focused on the effectiveness of ECCO2R. To the author's best knowledge, this is the first systematic review to focus on the adverse effects of this procedure. METHODS: We will conduct a systematic review of procedure-related adverse effects of ECCO2R systems...
2016: Systematic Reviews
https://www.readbyqxmd.com/read/27266291/removal-of-extracorporeal-carbon-dioxide-in-chronic-obstructive-pulmonary-disease-patients
#12
Fulsen Bozkuş, Bora Bilal, Hafize Öksüz
The use of invasive mechanical ventilation (IMV) procedures in chronic obstructive pulmonary disease (COPD) patients suffering from episodes of acute exacerbation are associated with high rates of mortality. In this case study, we describe the use of a new device for extracorporeal carbon dioxide removal (ECCO2R) that can provide partial respiratory support for patients where noninvasive ventilation (NIV) proved insufficient. The case described in this manuscript represents the first clinical feasibility study for the Hemolung device, and was also the first use and application of the device at our department...
December 0: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/27195746/a-retrospective-observational-case-series-of-low-flow-venovenous-extracorporeal-carbon-dioxide-removal-use-in-patients-with-respiratory-failure
#13
Caroline E Moss, Eleanor J Galtrey, Luigi Camporota, Chris Meadows, Stuart Gillon, Nicholas Ioannou, Nicholas A Barrett
We aimed to describe the use of venovenous extracorporeal carbon dioxide removal (ECCO2R) in patients with hypercapnic respiratory failure. We performed a retrospective case note review of patients admitted to our tertiary regional intensive care unit and commenced on ECCO2R from August 2013 to February 2015. Fourteen patients received ECCO2R. Demographic data, physiologic data (including pH and partial pressure of carbon dioxide in arterial blood [PaCO2]) when starting ECCO2R (t = 0), at 4 hourly intervals for the first 24 hours, then at 24 hour intervals until cessation of ECCO2R, and overall outcome were recorded...
July 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/27195133/vascular-access-for-extracorporeal-life-support-tips-and-tricks
#14
REVIEW
Jeremie Reeb, Anne Olland, Stephane Renaud, Anne Lejay, Nicola Santelmo, Gilbert Massard, Pierre-Emmanuel Falcoz
In thoracic surgery, extracorporeal life support (ECLS) techniques are performed to (I) provide a short to mid term extracorporeal mechanical support; (II) realize the gas exchanges; and (III)-depending the configuration of the circuit-substitute the failed heart function. The objective of this review is to describe the rational of the different ECLS techniques used in thoracic surgery and lung transplantation (LTx) with a specific attention to the vascular access. Venovenous extracorporeal membrane oxygenation (VV ECMO) is the most common ECLS technique used in thoracic surgery and represents the best strategy to support the lung function...
April 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27193131/extracorporeal-carbon-dioxide-removal-ecco2r-in-respiratory-deficiency-and-current-investigations-on-its-improvement-a-review
#15
Hany Hazfiza Manap, Ahmad Khairi Abdul Wahab
The implementation of extracorporeal carbon dioxide removal (ECCO2R) as one of the extracorporeal life support system is getting more attention today. Thus, the objectives of this paper are to study the clinical practice of commercial ECCO2R system, current trend of its development and also the perspective on future improvement that can be done to the existing ECCO2R system. The strength of this article lies in its review scope, which focuses on the commercial ECCO2R therapy in the market based on membrane lung and current investigation to improve the efficiency of the ECCO2R system, in terms of surface modification by carbonic anhydrase (CA) immobilization technique and respiratory electrodialysis (R-ED)...
May 18, 2016: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/27085737/novel-extracorporeal-therapies-for-combined-renal-pulmonary-dysfunction
#16
REVIEW
Stefano Romagnoli, Zaccaria Ricci, Claudio Ronco
In modern intensive care medicine, lungs and kidneys frequently are involved in the context of multiorgan failure. When organ dysfunction occurs, the primary clinical management of critically ill patients is based on support/replacement of organ function until recovery. Mechanical ventilation is the first-line intervention in case of respiratory failure, but in most severe cases may, itself, cause ventilator-induced lung injury. The same inflammatory mechanism also may harm the kidney through mediator spillover from the injured lungs into the bloodstream...
January 2016: Seminars in Nephrology
https://www.readbyqxmd.com/read/26966691/current-applications-for-the-use-of-extracorporeal-carbon-dioxide-removal-in-critically-ill-patients
#17
REVIEW
Luigi Camporota, Nicholas Barrett
Mechanical ventilation in patients with respiratory failure has been associated with secondary lung injury, termed ventilator-induced lung injury. Extracorporeal venovenous carbon dioxide removal (ECCO2R) appears to be a feasible means to facilitate more protective mechanical ventilation or potentially avoid mechanical ventilation in select patient groups. With this expanding role of ECCO2R, we aim to describe the technology and the main indications of ECCO2R.
2016: BioMed Research International
https://www.readbyqxmd.com/read/26861596/feasibility-and-safety-of-low-flow-extracorporeal-carbon-dioxide-removal-to-facilitate-ultra-protective-ventilation-in-patients-with-moderate-acute-respiratory-distress-sindrome
#18
Vito Fanelli, Marco V Ranieri, Jordi Mancebo, Onnen Moerer, Michael Quintel, Scott Morley, Indalecio Moran, Francisco Parrilla, Andrea Costamagna, Marco Gaudiosi, Alain Combes
BACKGROUND: Mechanical ventilation with a tidal volume (VT) of 6 mL/kg/predicted body weight (PBW), to maintain plateau pressure (Pplat) lower than 30 cmH2O, does not completely avoid the risk of ventilator induced lung injury (VILI). The aim of this study was to evaluate safety and feasibility of a ventilation strategy consisting of very low VT combined with extracorporeal carbon dioxide removal (ECCO2R). METHODS: In fifteen patients with moderate ARDS, VT was reduced from baseline to 4 mL/kg PBW while PEEP was increased to target a plateau pressure--(Pplat) between 23 and 25 cmH2O...
February 10, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/26831671/use-of-extracorporeal-carbon-dioxide-removal-ecco2r-in-239-intensive-care-units-results-from-a-french-national-survey
#19
LETTER
B Deniau, J D Ricard, J Messika, D Dreyfuss, Stephane Gaudry
No abstract text is available yet for this article.
April 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/26780677/carbon-dioxide-dialysis-in-a-swine-model-utilizing-systemic-and-regional-anticoagulation
#20
A S Sharma, P W Weerwind, O Bekers, E M Wouters, J G Maessen
BACKGROUND: Extracorporeal carbon dioxide removal (ECCO2R) has been gaining interest to potentially facilitate gas transfer and equilibrate mild to moderate hypercapnic acidosis, when standard therapy with non-invasive ventilation is deemed refractory. However, concern regarding the effectiveness of low-flow CO2 removal remains. Additionally, the prospect to steadily reduce hypercapnia via low-flow ECCO2R technique is limited, especially with regional anticoagulation which potentially reduces the risk of bleeding...
December 2016: Intensive Care Medicine Experimental
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