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https://www.readbyqxmd.com/read/28314743/adjunctive-clindamycin-for-cellulitis-a-clinical-trial-comparing-flucloxacillin-with-or-without-clindamycin-for-the-treatment-of-limb-cellulitis
#1
Richard Brindle, O Martin Williams, Paul Davies, Tim Harris, Heather Jarman, Alastair D Hay, Peter Featherstone
OBJECTIVE: To compare flucloxacillin with clindamycin to flucloxacillin alone for the treatment of limb cellulitis. DESIGN: Parallel, double-blinded, randomised controlled trial. SETTING: Emergency department attendances and general practice referrals within 20 hospitals in England. INTERVENTIONS: Flucloxacillin, at a minimum of 500 mg 4 times per day for 5 days, with clindamycin 300 mg 4 times per day for 2 days given orally versus flucloxacillin given alone...
March 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28303354/odontogenic-orbital-abscess-a-case-report-and-review-of-literature
#2
Pasquale Procacci, Alessandro Zangani, Alberto Rossetto, Alessandro Rizzini, Giovanni Zanette, Massimo Albanese
Odontogenic orbital abscess is a rare but well-documented complication of sinusitis and infections spreading from dental apical lesion. We report a case of orbital abscess with periorbital cellulitis, in a 35-year-old man with positive recent dental history of a periapical dental infection arising from the second upper left premolar spread into maxillary sinus. The patient has shown facial edema, ocular pain, ophthalmoplegia, proptosis, and initial visual symptoms. A surgical intervention to drain the abscess and a revision of the dental lesion and maxillary sinus were required...
March 16, 2017: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28301697/managing-opioid-withdrawal-for-hospital-patients-in-custody
#3
Connie R Shi, Manjinder S Kandola, Matthew Tobey, Elizabeth Singer
Dr. Brown, a hospitalist, admits Mark, a patient transferred from a local jail for management of cellulitis. The patient, who was taken into custody two days prior to hospital admission, has a history of intravenous heroin use. Mark explains that he had been prescribed buprenorphine-naloxone maintenance therapy for opioid use disorder for several years prior to being arrested and had not used other opioids during that time. As a policy, the jail where Mark is detained does not prescribe opioid agonists, and his maintenance therapy was stopped upon his arrival there...
March 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28296993/clinical-characteristics-and-outcomes-of-patients-with-cellulitis-requiring-intensive-care
#4
Duncan R Cranendonk, Lonneke A van Vught, Maryse A Wiewel, Olaf L Cremer, Janneke Horn, Marc J Bonten, Marcus J Schultz, Tom van der Poll, W Joost Wiersinga
Importance: Cellulitis is a commonly occurring skin and soft tissue infection and one of the most frequently seen dermatological diseases in the intensive care unit (ICU). However, clinical characteristics of patients with cellulitis requiring intensive care treatment are poorly defined. Necrotizing fasciitis is often confused for cellulitis at initial presentation and is considered to be more severe and thus has previously been described in more detail. Objective: To describe the clinical presentation and outcomes of patients with ICU-necessitating cellulitis and to compare them with patients with necrotizing fasciitis...
March 15, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28296037/laboratory-risk-indicator-for-necrotizing-fasciitis-score-for-early-diagnosis-of-necrotizing-fasciitis-in-darwin
#5
Vignesh Narasimhan, Geraldine Ooi, Stephanie Weidlich, Phillip Carson
BACKGROUND: Soft tissue infections are a major health burden in the Top End of the Northern Territory of Australia. Necrotizing fasciitis (NF) is associated with mortality rates from 8 to 40%. Early recognition and aggressive surgical debridement are the cornerstones of successful treatment. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score, developed by Wong et al., uses six routine biochemical variables to aid early diagnosis. We aim to assess the diagnostic efficacy of the LRINEC score in our population...
March 15, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28292273/ocular-bacterial-infections-at-quiha-ophthalmic-hospital-northern-ethiopia-an-evaluation-according-to-the-risk-factors-and-the-antimicrobial-susceptibility-of-bacterial-isolates
#6
Mebrahtu Teweldemedhin, Muthupandian Saravanan, Araya Gebreyesus, Dawit Gebreegziabiher
BACKGROUND: External and intraocular infections can lead to visual impairments, which is a major public health problem. Bacteria are the most frequent pathogens affecting ocular structures; the increasing rate of antimicrobial drug resistance is a worldwide concern. The aim of this study was to determine the occurrence of bacteria in ocular infections, their antimicrobial susceptibility patterns, and risk factors in bacterial ocular infection. METHODS: A hospital based cross-sectional study was conducted from September 2015 to December 2015 at Quiha Ophthalmic Hospital, Tigray, northern Ethiopia...
March 14, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28290979/orbital-cellulitis-in-a-psoriatic-patient-treated-with-adalimumab
#7
Vienna G Katana, Robert J Carpenter, John P Trafeli, Julia M Kwan
INTRODUCTION: Psoriatic patients on tumor necrosis factor alpha inhibitors (TNFi) may be at increased risk for upper respiratory tract infections, including chronic rhino-sinusitis (CRS). Rarely, CRS can progress to orbital cellulitis (OC), an emergent ophthalmic complication wherein respiratory flora from paranasal sinus disease intrude the retro-orbital space. MATERIALS AND METHODS: Single case report. RESULTS: We report the first case, to our knowledge, of an invasive sinusitis that rapidly evolved into OC in a patient receiving adalimumab treatment for plaque psoriasis and psoriatic arthritis...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290630/common-superficial-bursitis
#8
Morteza Khodaee
Superficial bursitis most often occurs in the olecranon and prepatellar bursae. Less common locations are the superficial infrapatellar and subcutaneous (superficial) calcaneal bursae. Chronic microtrauma (e.g., kneeling on the prepatellar bursa) is the most common cause of superficial bursitis. Other causes include acute trauma/hemorrhage, inflammatory disorders such as gout or rheumatoid arthritis, and infection (septic bursitis). Diagnosis is usually based on clinical presentation, with a particular focus on signs of septic bursitis...
February 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/28288090/clinical-study-of-an-online-tool-for-standardizing-hospital-care
#9
Mary J Burgess, Mark J Enzler, Deanne T Kashiwagi, Andi J Selby, M Rizwan Sohail, Paul R Daniels, Brian D Lahr, Farrell Lloyd, Larry D Baddour
We assessed if use of an online clinical decision support tool improved standardization and quality of care in hospitalized patients with lower extremity cellulitis (LEC). This was a 14-month preintervention and postintervention study of 85 LEC admissions. There was significantly higher usage of the online LEC care process model (CPM) in the postintervention phase (p < .001). There was a trend toward higher rates of appropriate antibiotic regimen in the postintervention group both initially and at discharge (p = ...
November 2016: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://www.readbyqxmd.com/read/28285868/more-than-meets-the-eye-klebsiella-pneumoniae-invasive-liver-abscess-syndrome-presenting-with-endophthalmitis
#10
Jan Van Keer, Karel Van Keer, Joachim Van Calster, Inge Derdelinckx
BACKGROUND: Endophthalmitis is a feared complication of pyogenic liver abscesses caused by hypervirulent Klebsiella pneumoniae strains. First described in East Asia in the 1980s, this invasive syndrome is only recently emerging in Europe and America. CASE REPORT: We describe an 84-year-old man who presented to the emergency department with fever, orbital cellulitis, and bilateral visual loss. Although the patient had no overt abdominal symptoms, computed tomography scan revealed a pyogenic liver abscess...
March 9, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28280672/obesity-related-risk-factors-in-implant-based-breast-reconstruction-using-alloderm
#11
James C Yuen, Cathryn A Coleman, Stephen W Erickson
With a population in which 70% of the patients were overweight or obese, we reviewed retrospectively 135 breasts of 70 consecutive patients who underwent implant-based immediate breast reconstruction using freeze-dried AlloDerm as the acellular dermal matrix. Several obesity-related parameters were evaluated to determine their possible correlation to early postoperative complications. We found that breast width and surface area of AlloDerm usage correlated with the development of infection and mastectomy skin flap necrosis...
February 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28278252/complement-inhibition-by-sarcoptes-scabiei-protects-streptococcus-pyogenes-an-in-vitro-study-to-unravel-the-molecular-mechanisms-behind-the-poorly-understood-predilection-of-s-pyogenes-to-infect-mite-induced-skin-lesions
#12
Pearl M Swe, Lindsay D Christian, Hieng C Lu, Kadaba S Sriprakash, Katja Fischer
BACKGROUND: On a global scale scabies is one of the most common dermatological conditions, imposing a considerable economic burden on individuals, communities and health systems. There is substantial epidemiological evidence that in tropical regions scabies is often causing pyoderma and subsequently serious illness due to invasion by opportunistic bacteria. The health burden due to complicated scabies causing cellulitis, bacteraemia and sepsis, heart and kidney diseases in resource-poor communities is extreme...
March 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28275981/clinical-profile-and-outcomes-of-management-of-orbital-cellulitis-in-upper-egypt
#13
Ahmed Mohamed Kamal Elshafei, Mohamed Farouk Sayed, Raafat Mohyeldeen Abdelrahman Abdallah
BACKGROUND: The purpose of this paper is to study the etiology, clinical findings, and outcomes of management of cases of orbital cellulitis treated in Minia University Hospital in Upper Egypt over the period of 6 years from July 2009 to July 2015. One-hundred two patients diagnosed to have orbital cellulitis were admitted to the hospital and treated on inpatient basis from July 2009 to July 2015. All patients were subjected to full ophthalmological examination, systemic evaluation, and ear, nose, and throat (ENT) consultation...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28274772/a-double-blind-randomised-controlled-trial-of-ibuprofen-compared-with-placebo-for-uncomplicated-cellulitis-of-the-upper-or-lower-limb
#14
Joshua S Davis, Carol Mackrow, Paula Binks, Wendy Fletcher, Pascale Dettwiller, Catherine Marshall, Jane Day, William Pratt, Steven Yc Tong
OBJECTIVES: Cellulitis is a common skin infection resulting in inflammation that may take weeks to resolve despite appropriate antibiotics. It is unclear whether the adjunctive use of non-steroidal anti-inflammatory drugs hastens the resolution of inflammation in patients with cellulitis. METHODS: We conducted a double-blind, randomised controlled trial comparing ibuprofen 400mg three times daily for five days with identical placebo in adults with uncomplicated cellulitis of the upper or lower limb who were treated with intravenous cefazolin via an outpatient parenteral antibiotic treatment service at one of two Australian hospitals...
March 5, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28272855/a-fifteen-year-experience-of-total-thyroidectomy-for-the-management-of-simple-multinodular-goitres-in-a-low-medium-income-country
#15
A O Afolabi, O O Ayandipo, O O Afuwape, O A Ogundoyin
INTRODUCTION: Total thyroidectomy as a treatment for simple multinodular goitre is not well recognised in most centres in low middle income countries. METHOD: This paper is a retrospective review of outcomes of total thyroidectomy for simple multinodular goitres in the last fifteen years in a tertiary hospital in Nigeria. RESULTS: A total of 652 thyroidectomies were done from January 2001 to December 2015. Simple multinodular goitres were indication for a total thyroidectomy in 447 patients (68...
November 2016: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28272717/our-supramicrosurgical-experience-of-lymphaticovenular-anastomosis-in-lymphoedema-patients-to-prevent-cellulitis
#16
P Gennaro, G Gabriele, C Salini, G Chisci, F Cascino, J-F Xu, C Ungari
OBJECTIVE: Aim of this paper is to present our reduction of the frequency of cellulitis before and after supramicrosurgical lymphaticovenular anastomosis (s-LVA) in lymphoedema patients, and discuss the possibility to perform this technique outside Japan. PATIENTS AND METHODS: 37 patients affected by lymphoedema were enrolled. All patients received preoperative indocyanine green lymphography. Under local anaesthesia s-LVA was performed on all patients. All patients were followed for 1 year...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28267078/pantoea-species-bacteremia-in-a-child-with-sickle-cell-disease-looking-for-a-culprit
#17
Marisa I Oliveira, Sara Batalha, Catarina Gouveia, Raquel Maia, Paula Kjöllerstrom
Pantoea agglomerans has been classically associated with cellulitis or synovitis secondary to penetrating trauma by vegetation. It is an infrequent cause of systemic infections. We describe the case of a 5-year-old girl with sickle cell disease with P. agglomerans bacteremia and review its potential causes.
March 6, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28259281/diagnosis-and-arthroscopic-management-of-dorsal-wrist-capsular-impingement
#18
Andrew P Matson, Travis J Dekker, Alexander J Lampley, Marc J Richard, Fraser J Leversedge, David S Ruch
PURPOSE: Dorsal wrist capsular impingement (DWCI) is characterized by pain attributable to impingement of dorsal capsular tissue during wrist extension. The diagnostic criteria and management algorithm for this condition have not been well established. The aims of our study were (1) to retrospectively review the clinical presentation and arthroscopic findings of patients treated surgically for DWCI and (2) to evaluate the outcomes of arthroscopic debridement for this condition. METHODS: A total of 19 patients were treated with arthroscopic debridement for isolated DWCI from 2006 to 2015 by two surgeons (M...
March 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28256903/mr-imaging-in-patients-with-male-to-female-sex-reassignment-surgery-postoperative-anatomy-and-complications
#19
Michele Bertolotto, Giovanni Liguori, Stefano Bucci, Mariano Iannelli, Francesca Vedovo, Nicola Pavan, Carlo Trombetta, Lorenzo Egildo Derchi
OBJECTIVES: To investigate the role of MRI in evaluation of both the new female anatomy and complications in male-to-female sex reassignment surgery (MtF-SRS). METHODS: 71 consecutive patients with MtF-SRS had 74 MRI (age range, 21-63 years; mean [± SD] age, 36 ± 10 years; median age, 37 years). In 47 patients MRI was performed to rule-out early postoperative complications after gender conversion (n=40), vaginoplasty (n=6), or remodelling of the labia majora (n=1)...
March 3, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28254446/necrotic-intraocular-retinoblastoma-associated-with-orbital-cellulitis
#20
Hilal Nalci, Kaan Gündüz, Esra Erden
Orbital cellulitis associated with retinoblastoma is uncommon and is characterised by non-infectious inflammation of the periorbital structures. The underlying mechanism is thought to be necrosis of the intraocular tumor leading to intraocular and periorbital inflammation. We report two retinoblastoma patients who presented with an orbital cellulitis-like picture. and discuss clinical characteristics, histopathologic features, and treatment.
February 27, 2017: Survey of Ophthalmology
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