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https://www.readbyqxmd.com/read/29336134/treatment-of-tinnitus-a-scoping-review
#1
Sujoy Kumar Makar, Geetha Mukundan, Geeta Gore
BACKGROUND: Tinnitus is a perception of an auditory sensation without the presence of an external sound. It has devastating impact on the quality of life and psychosocial aspect of the sufferer. Mechanisms of tinnitus not clear; however, its management include counselling, hearing aids, tinnitus masking, relaxation therapy, cognitive behaviour therapy and tinnitus retraining therapy. OBJECTIVE: To conduct a scoping review to explore the role of counselling, hearing aids, tinnitus masking, relaxation therapy, cognitive-behavioural therapy and tinnitus retraining therapy in India...
December 1, 2017: International Tinnitus Journal
https://www.readbyqxmd.com/read/29329316/electroencephalography-power-and-coherence-changes-with-age-and-motor-skill-development-across-the-first-half-year-of-life
#2
Ran Xiao, Joanne Shida-Tokeshi, Douglas L Vanderbilt, Beth A Smith
Existing research in infants has correlated electroencephalography (EEG) measures of power and coherence to cognitive development and to locomotor experience, but only in infants older than 5 months of age. Our goal was to explore the relationship between EEG measures of power and coherence and motor skill development in younger infants who are developing reaching skill. Twenty-one infants with typical development between 38 and 203 days of age participated. Longitudinal EEG recording sessions were recorded in monthly increments, with 3-5 sessions acquired for 19 participants and 1 session for 2 participants, resulting in 71 sessions in total...
2018: PloS One
https://www.readbyqxmd.com/read/29305533/perceptual-surprise-improves-action-stopping-by-non-selectively-suppressing-motor-activity-via-a-neural-mechanism-for-motor-inhibition
#3
Isabella Dutra, Darcy A Waller, Jan R Wessel
Motor inhibition is a cognitive control ability that allows humans to rapidly stop actions even after initiation. Understanding and improving motor inhibition could benefit adaptive behavior in both health and disease. We recently found that presenting surprising, task-unrelated sounds when stopping is necessary improves the likelihood of successful stopping. In the current study, we investigated the neural underpinnings of this effect. Specifically, we tested whether surprise-related stopping improvements are due to a genuine increase in motor inhibition...
January 5, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29304418/cortical-sources-of-resting-state-electroencephalographic-rhythms-probe-brain-function-in-na%C3%A3-ve-hiv-individuals
#4
Claudio Babiloni, Giuseppe Noce, Alfredo Pennica, Paolo Onorati, Paolo Capotosto, Claudio Del Percio, Paolo Roma, Valentina Correr, Elisa Piccinni, Ginevra Toma, Andrea Soricelli, Francesco Di Campli, Laura Gianserra, Lorenzo Ciullini, Antonio Aceti, Elisabetta Teti, Loredana Sarmati, Gloria Crocetti, Raffaele Ferri, Valentina Catania, Maria Teresa Pascarelli, Massimo Andreoni, Stefano Ferracuti
OBJECTIVE: Here we evaluated the hypothesis that resting state electroencephalographic (EEG) cortical sources correlated with cognitive functions and discriminated asymptomatic treatment-naïve HIV subjects (no AIDS). METHODS: EEG, clinical, and neuropsychological data were collected in 103 treatment-naïve HIV subjects (88 males; mean age 39.8 years ± 1.1 standard error of the mean, SE). An age-matched group of 70 cognitively normal and HIV-negative (Healthy; 56 males; 39...
December 20, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29299973/how-anaesthesiologists-understand-difficult-airway-guidelines-an-interview-study
#5
Kati Knudsen, Ulrika Pöder, Ulrica Nilsson, Marieann Högman, Anders Larsson, Jan Larsson
BACKGROUND: In the practice of anaesthesia, clinical guidelines that aim to improve the safety of airway procedures have been developed. The aim of this study was to explore how anaesthesiologists understand or conceive of difficult airway management algorithms. METHODS: A qualitative phenomenographic design was chosen to explore anaesthesiologists' views on airway algorithms. Anaesthesiologists working in three hospitals were included. Individual face-to-face interviews were conducted...
January 4, 2018: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/29299776/motivation-enhances-control-of-positive-and-negative-emotional-distractions
#6
Amy T Walsh, David Carmel, David Harper, Gina M Grimshaw
Using cognitive control to ignore distractions is essential for successfully achieving our goals. In emotionally-neutral contexts, motivation can reduce interference from irrelevant stimuli by enhancing cognitive control. However, attention is commonly biased towards emotional stimuli, making them potent distractors. Can motivation aid control of emotional distractions, and does it do so similarly for positive and negative stimuli? Here, we examined how task motivation influences control of distraction from positive, negative, and neutral scenes...
January 3, 2018: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/29290048/screening-and-detection-of-delirium-in-older-ed-patients-performance-of-the-modified-confusion-assessment-method-for-the-emergency-department-mcam-ed-a-two-step-tool
#7
Wolfgang Hasemann, Florian F Grossmann, Rahel Stadler, Roland Bingisser, Dieter Breil, Martina Hafner, Reto W Kressig, Christian H Nickel
Delirium is frequent in older Emergency Department (ED) patients, but detection rates for delirium in the ED are low. To aid in identifying delirium, we developed and implemented a two-step systematic delirium screening and assessment tool in our ED: the modified Confusion Assessment Method for the Emergency Department (mCAM-ED). Components of the mCAM-ED include: (1) screening for inattention, the main feature of delirium, which was performed with the Months Backwards Test (MBT); (2) delirium assessment based on a structured interview with questions from the Mental Status Questionnaire by Kahn et al...
December 30, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/29285052/suppression-of-alzheimer-s-disease-related-phenotypes-by-the-heat-shock-protein-70-inducer-geranylgeranylacetone-in-app-ps1-transgenic-mice-via-the-erk-p38-mapk-signaling-pathway
#8
Yuan Sun, Jiang-Rong Zhang, Shuyan Chen
HSP70 overexpression has a remedying effect in neurodegenerative diseases. In Alzheimer's disease (AD), the suppressive effects of HSP70 overexpression on AD-related phenotypes and the underlying mechanisms are unknown. In the current study, the effect of geranylgeranylacetone (GGA), a non-toxic inducer of heat shock protein (HSP)-70 expression, on cognitive function and other pathological phenotypes were evaluated in APP/PS1 mice. It was observed that all doses of orally administered GGA (200, 400, and 800 mg/kg/day) improved cognitive deficit (P<0...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29283237/memory-cognition-and-the-endogenous-evoked-potentials-of-the-brain-the-estimation-of-the-disturbance-of-cognitive-functions-and-capacity-of-working-memory-without-the-psychological-testing
#9
V V Gnezditskiy, O S Korepina, A V Chatskaya, O I Klochkova
Cognition, cognitive and memory impairments is widely discussed in the literature, especially in the psycho physiological and the neurologic. In essence, this literature is dedicated to the psycho physiological tests, different scales. However, instrument neurophysiologic methods not so widely are used for these purposes. This review is dedicated to the instrument methods of neurophysiology, in particular to the endogenous evoked potentials method Р 300 (by characteristic latency 300 ms), in the estimation of cognitive functions and memory, to their special features dependent on age and to special features to their changes with the pathology...
January 2017: Uspekhi Fiziologicheskikh Nauk
https://www.readbyqxmd.com/read/29280296/lock-and-chop-a-novel-method-for-the-generation-of-a-pick1-pdz-domain-and-piperidine-based-inhibitor-co-crystal-structure
#10
Douglas J Marcotte, Jean-Christophe Hus, Charles C Banos, Craig Wildes, Robert Arduini, Chris Bergeron, Catherine A Hession, Darren P Baker, Edward Lin, Kevin M Guckian, Anthone W Dunah, Laura F Silvian
The membrane protein interacting with kinase C1 (PICK1) plays a trafficking role in the internalization of neuron receptors such as the amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptor. Reduction of surface AMPA type receptors on neurons reduces synaptic communication leading to cognitive impairment in progressive neurodegenerative diseases such as Alzheimer disease. The internalization of AMPA receptors is mediated by the PDZ domain of PICK1 which binds to the GluA2 subunit of AMPA receptors and targets the receptor for internalization through endocytosis, reducing synaptic communication...
December 27, 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/29279726/hearing-aids-indications-technology-adaptation-and-quality-control
#11
REVIEW
Ulrich Hoppe, Gerhard Hesse
Hearing loss can be caused by a number of different pathological conditions. Some of them can be successfully treated, mainly by surgery, depending on the individual's disease process. However, the treatment of chronic sensorineural hearing loss with damaged cochlear structures usually needs hearing rehabilitation by means of technical amplification. During the last two decades tremendous improvements in hearing aid technology led to a higher quality of the hearing rehabilitation process. For example, due to sophisticated signal processing acoustic feedback could be reduced and hence open fitting options are available even for more subjects with higher degrees of hearing loss...
2017: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
https://www.readbyqxmd.com/read/29258525/advancing-perinatal-patient-safety-through-application-of-safety-science-principles-using-health-it
#12
Jennifer Webb, Asta Sorensen, Samantha Sommerness, Beth Lasater, Kamila Mistry, Leila Kahwati
BACKGROUND: The use of health information technology (IT) has been shown to promote patient safety in Labor and Delivery (L&D) units. The use of health IT to apply safety science principles (e.g., standardization) to L&D unit processes may further advance perinatal safety. METHODS: Semi-structured interviews were conducted with L&D units participating in the Agency for Healthcare Research and Quality's (AHRQ's) Safety Program for Perinatal Care (SPPC) to assess units' experience with program implementation...
December 19, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/29251380/the-relationship-between-dsm-5-ptsd-symptom-clusters-and-alcohol-misuse-among-military-veterans
#13
Jessica L Walton, Amanda M Raines, Lisa-Ann J Cuccurullo, Desirae N Vidaurri, Margo C Villarosa-Hurlocker, C L Franklin
BACKGROUND AND OBJECTIVES: Prior research has revealed a strong relationship between Posttraumatic Stress Disorder (PTSD) and alcohol misuse. However, previous attempts to understand nuanced associations between PTSD symptom clusters and alcohol misuse within military veteran samples have produced mixed results. In an attempt to better understand the associations between PTSD and alcohol misuse, the current study examined the unique relationships between the newly classified Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) PTSD symptom clusters and alcohol misuse in an outpatient sample of military veterans seeking treatment for PTSD and Substance Use Disorders...
December 18, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/29247111/what-interventions-are-used-to-improve-exercise-adherence-in-older-people-and-what-behavioural-techniques-are-they-based-on-a-systematic-review
#14
Jonathan Room, Erin Hannink, Helen Dawes, Karen Barker
OBJECTIVES: To conduct a systematic review of interventions used to improve exercise adherence in older people, to assess the effectiveness of these interventions and to evaluate the behavioural change techniques underpinning them using the Behaviour Change Technique Taxonomy (BCTT). DESIGN: Systematic review. METHODS: A search was conducted on AMED, BNI, CINAHL, EMBASE, MEDLINE and PsychINFO databases. Randomised controlled trials that used an intervention to aid exercise adherence and an exercise adherence outcome for older people were included...
December 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/29246336/hearing-loss-after-cardiac-surgery-in-infancy-an-unintended-consequence-of-life-saving-care
#15
Madison A Grasty, Richard F Ittenbach, Carol Knightly, Cynthia B Solot, Marsha Gerdes, Judy C Bernbaum, Gil Wernovsky, Thomas L Spray, Susan C Nicolson, Robert R Clancy, Daniel J Licht, Elaine Zackai, J William Gaynor, Nancy B Burnham
OBJECTIVES: To investigate the prevalence of hearing loss after cardiac surgery in infancy, patient and operative factors associated with hearing loss, and the relationship of hearing loss to neurodevelopmental outcomes. STUDY DESIGN: Audiologic and neurodevelopmental evaluations were conducted on 348 children who underwent repair of congenital heart disease at the Children's Hospital of Philadelphia as part of a prospective study evaluating neurodevelopmental outcomes at 4 years of age...
January 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29242975/reinterpretation-in-visual-imagery-is-possible-without-visual-cues-a-validation-of-previous-research
#16
Kevin L Kamermans, Wim Pouw, Fred W Mast, Fred Paas
Is visual reinterpretation of bistable figures (e.g., duck/rabbit figure) in visual imagery possible? Current consensus suggests that it is in principle possible because of converging evidence of quasi-pictorial functioning of visual imagery. Yet, studies that have directly tested and found evidence for reinterpretation in visual imagery, allow for the possibility that reinterpretation was already achieved during memorization of the figure(s). One study resolved this issue, providing evidence for reinterpretation in visual imagery (Mast and Kosslyn, Cognition 86:57-70, 2002)...
December 14, 2017: Psychological Research
https://www.readbyqxmd.com/read/29231140/up-regulation-of-dmn-connectivity-in-mild-cognitive-impairment-via-network-based-cognitive-training
#17
Matteo De Marco, Francesca Meneghello, Cristina Pilosio, Jessica Rigon, Annalena Venneri
BACKGROUND: Previous work designed a network-based protocol of cognitive training. This programme exploits a mechanism of induced task-oriented co-activation of multiple regions that are part of the default mode network (DMN), to induce functional rewiring and increased functional connectivity within this network. OBJECTIVE: In this study, the programme was administered to patients with a diagnosis of mild cognitive impairment to test its effects in a clinical sample...
December 11, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/29227306/big-data-analytical-approaches-to-the-nacc-dataset-aiding-preclinical-trial-enrichment
#18
Ming Lin, Pinghua Gong, Tao Yang, Jieping Ye, Roger L Albin, Hiroko H Dodge
BACKGROUND: Clinical trials increasingly aim to retard disease progression during presymptomatic phases of Mild Cognitive Impairment (MCI) and thus recruiting study participants at high risk for developing MCI is critical for cost-effective prevention trials. However, accurately identifying those who are destined to develop MCI is difficult. Collecting biomarkers is often expensive. METHODS: We used only noninvasive clinical variables collected in the National Alzheimer's Coordinating Center (NACC) Uniform Data Sets version 2...
December 7, 2017: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/29224583/nutrients-for-neurocognition-in-health-and-disease-measures-methodologies-and-mechanisms
#19
Andrew Scholey
Effective pharmaceutical treatments for age-related cognitive decline have proved elusive. There is, however, compelling evidence that nutritional status and supplementation could play crucial roles in modifying the expression of cognitive change through the lifespan. Subjective memory impairment and mild cognitive impairment can be harbingers of dementia but this is by no means inevitable. Neurocognitive change is influenced by a variety of processes, many of which are involved in other aspects of systemic health, including cardiovascular function...
December 11, 2017: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/29223185/aiding-medical-professionals-in-fitness-to-drive-screenings-for-elderly-drivers-development-of-an-office-based-screening-tool
#20
Judith H J Urlings, Ariane Cuenen, Tom Brijs, Mark Lutin, Ellen M M Jongen
BACKGROUND: Elderly drivers are an increasing group in society. Previous research has found that functional and cognitive abilities are more important for driving abilities than biological age. In an attempt to conserve independent mobility for elderly drivers, many researchers have focused on elderly drivers diagnosed with cognitive decline (mild cognitive impairment or mild Dementia). This study is the first to focus on elderly drivers with cognitive complaints or suspected of diminished fitness to drive by an (in)formal caregiver as an at-risk group...
December 10, 2017: International Psychogeriatrics
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