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https://www.readbyqxmd.com/read/28548462/neurocognitive-mechanisms-of-real-world-autobiographical-memory-retrieval-insights-from-studies-using-wearable-camera-technology
#1
REVIEW
Tiffany E Chow, Jesse Rissman
In recent years, investigation into the cognitive and neural mechanisms of autobiographical memory has been aided by the use of experimental paradigms incorporating wearable camera technology. By effortlessly capturing first-person images of one's life events, these cameras provide a rich set of naturalistic stimuli that can later be used to trigger the recall of specific episodes. Here, we chronicle the development and progression of such studies in behavioral and neuroimaging examinations of both clinical and nonclinical adult populations...
May 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28546307/the-right-lateral-cerebellum-represents-linguistic-predictability
#2
Elise Lesage, Peter C Hansen, R Chris Miall
Mounting evidence indicates that posterolateral portions of the cerebellum (right Crus I/II) contribute to language processing, but the nature of this role remains unclear. Based on a well-supported theory of cerebellar motor function, which ascribes to the cerebellum a role in short-term prediction through internal modeling, we hypothesize that right cerebellar Crus I/II supports prediction of upcoming sentence content.We tested this hypothesis using event-related fMRI in human subjects by manipulating the predictability of written sentences...
May 25, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28544426/the-catechol-o-methyltransferase-comt-val158met-genotype-modulates-working-memory-related-dorsolateral-prefrontal-response-and-performance-in-bipolar-disorder
#3
K W Miskowiak, H L Kjaerstad, M M Støttrup, A M Svendsen, K M Demant, L K Hoeffding, T M Werge, K E Burdick, K Domschke, A F Carvalho, E Vieta, M Vinberg, L V Kessing, H R Siebner, J Macoveanu
OBJECTIVES: Cognitive dysfunction affects a substantial proportion of patients with bipolar disorder (BD), and genetic-imaging paradigms may aid in the elucidation of mechanisms implicated in this symptomatic domain. The Val allele of the functional Val158Met polymorphism of the catechol-O-methyltransferase (COMT) gene is associated with reduced prefrontal cortex dopamine and exaggerated working memory-related prefrontal activity. This functional magnetic resonance imaging (fMRI) study investigated for the first time whether the COMT Val158Met genotype modulates prefrontal activity during spatial working memory in BD...
May 23, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28541903/alzheimer-s-disease-classification-based-on-individual-hierarchical-networks-constructed-with-3d-texture-features
#4
Jin Liu, Jianxin Wang, Bin Hu, Fang-Xiang Wu, Yi Pan
Brain network plays an important role in representing abnormalities in Alzheimers disease (AD) and mild cognitive impairment (MCI), which includes MCIc (MCI converted to AD) and MCInc (MCI not converted to AD). In our previous study, we proposed an AD classification approach based on individual hierarchical networks constructed with 3D texture features of brain images. However, we only used edge features of the networks without node features of the networks. In this study, we propose a framework of the combination of multiple kernels to combine edge features and node features for AD classification...
May 23, 2017: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/28541583/consumer-decision-making-abilities-and-long-term-care-insurance-purchase
#5
Brian E McGarry, Helena Tempkin-Greener, David C Grabowski, Benjamin P Chapman, Yue Li
Objectives: To determine the impact of consumer decision-making abilities on making a long-term care insurance (LTCi) purchasing decision that is consistent with normative economic predictions regarding policy ownership. Method: Using data from the Health and Retirement Study, multivariate analyses are implemented to estimate the effect of decision-making ability factors on owning LTCi. Stratified multivariate analyses are used to examine the effect of decision-making abilities on the likelihood of adhering to economic predictions of LTCi ownership...
May 25, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28541549/cognitive-development-in-children-up-to-age-11-years-born-after-art-a-longitudinal-cohort-study
#6
Anna Barbuscia, Melinda C Mills
STUDY QUESTION: How does the cognitive development of children conceived after ART (IVF and ICSI) - measured as cognitive skills at age 3, 5, 7 and 11 years - differ over time from those born after natural conception (NC)? SUMMARY ANSWER: Improved measures of cognitive development up to age 5 years were recorded in children conceived with ART compared to NC, which attenuates by 11 years, with ART children still scoring slightly better than NC children. WHAT IS KNOWN ALREADY: Results on the cognitive outcomes of children conceived after ART have been highly contradictory...
May 24, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28535277/sensory-impairments-and-cognitive-function-in-middle-aged-adults
#7
Carla R Schubert, Karen J Cruickshanks, Mary E Fischer, Yanjun Chen, Barbara E K Klein, Ronald Klein, A Alex Pinto
Background: Hearing, visual, and olfactory impairments have been associated with cognitive impairment in older adults but less is known about associations with cognitive function in middle-aged adults. Methods: Sensory and cognitive functions were measured on participants in the baseline examination (2005-2008) of the Beaver Dam Offspring Study. Cognitive function was measured with the Trail Making tests A (TMTA) and B (TMTB) and the Grooved Peg Board test. Pure-tone audiometry, Pelli-Robson letter charts, and the San Diego Odor Identification test were used to measure hearing, contrast sensitivity, and olfaction, respectively...
May 23, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28527854/barriers-to-initiation-of-extended-release-naltrexone-among-hiv-infected-adults-with-alcohol-use-disorders
#8
Hélène Chokron Garneau, Alexandra Venegas, Richard Rawson, Lara A Ray, Suzette Glasner
Alcohol consumption is a major risk factor for the acquisition of HIV/AIDS and is associated with greater disease burden and mortality among those who become HIV-infected. Of the extant pharmacological treatments for alcohol use disorders, naltrexone is recognized as one of the most efficacious, producing robust reductions in alcohol craving and use. Given that treatment with oral naltrexone has been limited by problems with adherence, which are particularly prevalent among individuals with multiple chronic, co-occurring conditions, long-acting formulations may be a promising approach for HIV-infected substance users...
May 11, 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28523960/the-health-literacy-dyad-the-contribution-of-future-gps-in-england
#9
Oana R Groene, Jane Wills, Nicola Crichton, Gill Rowlands, Rima R Rudd
BACKGROUND: Health literacy studies have primarily focused on the cognitive and social skills of individuals needed to gain access to, understand, and use health information. This area of study is undergoing a paradigm shift with increased attention being paid to the skills of practitioners and an examination of their contribution to the link between literacy and health outcomes. The aim of this study was to describe the health literacy related competencies of General Practice (GP) trainees who will soon be responsible for the clinical encounter...
May 19, 2017: Education for Primary Care
https://www.readbyqxmd.com/read/28522893/hearcare-hearing-and-communication-assistance-for-resident-engagement
#10
REVIEW
Catherine V Palmer, Reem Mulla, Elizabeth Dervin, Kathleen Costigan Coyan
Impaired hearing is related to poor health outcomes, including compromised cognitive function, in aging individuals. Hearing loss is the third most common chronic health condition after arthritis and heart disease in older adults and the fourth most detrimental condition related to quality of life in older adults. Only 18% of aging adults who have impactful hearing loss actually use custom-fit amplification. Therefore, the majority of aging individuals entering senior living facilities will have untreated hearing loss...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28522892/enhancing-communication-in-adults-with-dementia-and-age-related-hearing-loss
#11
REVIEW
Sara K Mamo, Esther Oh, Frank R Lin
For many adults with dementia, age-related hearing loss is undiagnosed and/or untreated. Untreated hearing loss can exacerbate common dementia-related behavioral symptoms, such as depression, apathy, agitation. Despite the potential benefits to the individual and the family, pursuing and adopting hearing aids for persons with dementia presents with many challenges. As such, this group of vulnerable older adults is well suited for alternative approaches that adopt an interventional audiology framework. This article reviews alternative hearing care models that we have tested when working with older adults with cognitive impairments...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28512046/risk-factors-for-preoperative-seizures-and-loss-of-seizure-control-in-patients-undergoing-surgery-for-metastatic-brain-tumors
#12
Adela Wu, Jon D Weingart, Gary L Gallia, Michael Lim, Henry Brem, Chetan Bettegowda, Kaisorn L Chaichana
OBJECTIVE: Metastatic brain tumors are the most common brain tumors in adults. Patients with metastatic brain tumors have poor prognoses with median survival of 6-12 months. Seizures are a major presenting symptom and cause of morbidity and mortality. Risk factors for the onset of preoperative seizures and postoperative seizure control are examined. METHODS: Adult patients who underwent resection of one or more brain metastases at a single institution between 1998 and 2011 were retrospectively reviewed...
May 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28511634/human-factors-considerations-in-designing-for-infection-prevention-and-control-in-neonatal-care-findings-from-a-pre-design-inquiry
#13
Chantal Trudel, Sue Cobb, Kathryn Momtahan, Janet Brintnell, Ann Mitchell
Qualitative data collection methods drawn from the early stages of human-centred design frameworks combined with thematic analysis were used to develop an understanding of infection prevention practice within an existing neonatal intensive care unit. Findings were used to generate a framework of understanding which in turn helped inform a baseline approach for future research and design development. The study revealed that a lack of clarity between infection transmission zones and a lack of design attributes needed to uphold infection prevention measures may be undermining healthcare workers' understanding and application of good practice...
May 17, 2017: Ergonomics
https://www.readbyqxmd.com/read/28509579/findings-of-cognitive-impairment-at-high-altitude-relationships-to-acetazolamide-use-and-acute-mountain-sickness
#14
Lara Phillips, Buddha Basnyat, Yuchiao Chang, Erik R Swenson, N Stuart Harris
Phillips, Lara, Buddha Basnyat, Yuchiao Chang, Erik R. Swenson, and N. Stuart Harris. Findings of cognitive impairment at high altitude: relationships to acetazolamide use and acute mountain sickness. High Alt Med Biol. 00:000-000, 2017.-Objective: Acute mountain sickness (AMS) is defined by patient-reported symptoms using the Lake Louise Score (LLS), which provides limited insight into any possible underlying central nervous system (CNS) dysfunction. Some evidence suggests AMS might coexist with altered neural functioning...
May 16, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28507895/diverging-volumetric-trajectories-following-pediatric-traumatic-brain-injury
#15
Emily L Dennis, Joshua Faskowitz, Faisal Rashid, Talin Babikian, Richard Mink, Christopher Babbitt, Jeffrey Johnson, Christopher C Giza, Neda Jahanshad, Paul M Thompson, Robert F Asarnow
Traumatic brain injury (TBI) is a significant public health concern, and can be especially disruptive in children, derailing on-going neuronal maturation in periods critical for cognitive development. There is considerable heterogeneity in post-injury outcomes, only partially explained by injury severity. Understanding the time course of recovery, and what factors may delay or promote recovery, will aid clinicians in decision-making and provide avenues for future mechanism-based therapeutics. We examined regional changes in brain volume in a pediatric/adolescent moderate-severe TBI (msTBI) cohort, assessed at two time points...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28505989/pediatric-robotic-rehabilitation-current-knowledge-and-future-trends-in-treating-children-with-sensorimotor-impairments
#16
Konstantinos P Michmizos, Hermano Igo Krebs
BACKGROUND: Robot-aided sensorimotor therapy imposes highly repetitive tasks that can translate to substantial improvement when patients remain cognitively engaged into the clinical procedure, a goal that most children find hard to pursue. Knowing that the child's brain is much more plastic than an adult's, it is reasonable to expect that the clinical gains observed in the adult population during the last two decades would be followed up by even greater gains in children. Nonetheless, and despite the multitude of adult studies, in children we are just getting started: There is scarcity of pediatric robotic rehabilitation devices that are currently available and the number of clinical studies that employ them is also very limited...
May 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28505355/uncovering-the-neuroanatomical-correlates-of-cognitive-affective-and-conative-theory-of-mind-in-pediatric-traumatic-brain-injury-a-neural-systems-perspective
#17
Nicholas P Ryan, Cathy Catroppa, Richard Beare, Timothy J Silk, Stephen J Hearps, Miriam H Beauchamp, Keith Owen Yeates, Vicki A Anderson
Deficits in Theory of Mind (ToM) are common after neurological insult acquired in the first and second decade of life, however the contribution of large-scale neural networks to ToM deficits in children with brain injury is unclear. Using pediatric traumatic brain injury (TBI) as a model, this study investigated the sub-acute effect of brain injury on gray-matter volume of three large-scale, domain-general brain networks (the Default Mode Network, DMN; the Central Executive Network, CEN; and the Salience Network, SN), as well as two domain-specific neural networks implicated in social-affective processes (the Cerebro-Cerebellar Mentalizing Network, CCMN, and the Mirror Neuron/Empathy Network, MNEN)...
May 15, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28499294/h%C3%A3-rger%C3%A3-te-indikationen-technologie-anpassung-und-qualit%C3%A3-tskontrolle
#18
Ulrich Hoppe, Gerhard Hesse
Hearing loss can be caused by a number of different pathological conditions. Some of them can be successfully treated, mainly by surgery, depending on the individual's disease process. However, the treatment of chronic sensorineural hearing loss with damaged cochlear structures usually needs hearing rehabilitation by means of technical amplification. During the last 2 decades tremendous improvements in hearing aid technology led to a higher quality in the hearing rehabilitation process. For example, due to sophisticated signal processing the acoustic feedback path could be reduced and hence open fitting options are available for even more subjects...
April 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28495369/group-level-spatio-temporal-pattern-recovery-in-meg-decoding-using-multi-task-joint-feature-learning
#19
Seyed Mostafa Kia, Fabian Pedregosa, Anna Blumenthal, Andrea Passerini
BACKGROUND: The use of machine learning models to discriminate between patterns of neural activity has become in recent years a standard analysis approach in neuroimaging studies. Whenever these models are linear, the estimated parameters can be visualized in the form of brain maps which can aid in understanding how brain activity in space and time underlies a cognitive function. However, the recovered brain maps often suffer from lack of interpretability, especially in group analysis of multi-subject data...
May 8, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28493728/internal-and-community-recourses-contribution-to-level-of-posttraumatic-symptoms-the-case-of-tourists-after-the-earthquake-in-nepal-2015
#20
Haya Itzhaky, Shlomit Weiss-Dagan, Orit Taubman-Ben-Ari
OBJECTIVE: The current study focused on tourists who were caught in the middle of Nepal's, 2015 earthquake, and survived. We examined the contribution of internal (coping flexibility and emotional regulation) and community resources (sense of belonging to the community) to tourist's level of post traumatic stress disorder symptoms. METHOD: A cross-sectional sample survey was conducted to collect data from 145 tourists between 2 week to 3 months after the earthquake...
May 11, 2017: Psychological Trauma: Theory, Research, Practice and Policy
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