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caffeine and performance

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https://www.readbyqxmd.com/read/28918319/determination-of-chlorogenic-acids-and-caffeine-in-homemade-brewed-coffee-prepared-under-various-conditions
#1
Jong-Sup Jeon, Han-Taek Kim, Il-Hyung Jeong, Se-Ra Hong, Moon-Seog Oh, Kwang-Hee Park, Jae-Han Shim, A M Abd El-Aty
Coffee, a complex mixture of more than 800 volatile compounds, is one of the most valuable commodity in the world, whereas caffeine and chlorogenic acids (CGAs) are the most common compounds. CGAs are mainly composed of caffeoylquinic acids (CQAs), dicaffeoylquinic acids (diCQAs), and feruloylquinic acids (FQAs). The major CGAs in coffee are neochlorogenic acid (3-CQA), cryptochlorogenic acid (4-CQA), and chlorogenic acid (5-CQA). Many studies have shown that it is possible to separate the isomers of FQAs by high-performance liquid chromatography (HPLC)...
August 31, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28918222/vision-assessments-and-interventions-for-infants-0-2-years-at-high-risk-for-cerebral-palsy-a-systematic-review
#2
REVIEW
Olena D Chorna, Andrea Guzzetta, Nathalie L Maitre
We performed a systematic review and evaluated the level of evidence of vision interventions and assessments for infants at high risk for or with a diagnosis of cerebral palsy from 0 to 2 years of age. Articles were evaluated based on the level of methodologic quality, evidence, and clinical utilization. Thirty publications of vision assessments and five of vision interventions met criteria for inclusion. Assessments included standard care neuroimaging, electrophysiology, and neuro-ophthalmologic examination techniques that are utilized clinically with any preverbal or nonverbal pediatric patient...
July 20, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28917947/effect-of-meal-glycemic-load-and-caffeine-consumption-on-prolonged-monotonous-driving-performance
#3
Christopher Bragg, Ben Desbrow, Susan Hall, Christopher Irwin
OBJECTIVE: Monotonous driving involves low levels of stimulation and high levels of repetition and is essentially an exercise in sustained attention and vigilance. The aim of this study was to determine the effects of consuming a high or low glycemic load meal on prolonged monotonous driving performance. The effect of consuming caffeine with a high glycemic load meal was also examined. METHOD: Ten healthy, non-diabetic participants (7 males, age 51±7yrs, mean±SD) completed a repeated measures investigation involving 3 experimental trials...
September 13, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28915479/effect-of-design-and-operational-conditions-on-the-performance-of-subsurface-flow-treatment-wetlands-emerging-organic-contaminants-as-indicators
#4
Stefanie Kahl, Jaime Nivala, Manfred van Afferden, Roland A Müller, Thorsten Reemtsma
Six pilot-scale subsurface flow treatment wetlands loaded with primary treated municipal wastewater were monitored over one year for classical wastewater parameters and a set of emerging organic compounds (EOCs) serving as process indicators for biodegradation: caffeine, ibuprofen, naproxen, benzotriazole, diclofenac, acesulfame, and carbamazepine. The wetland technologies investigated included conventional horizontal flow, unsaturated vertical flow (single and two-stage), horizontal flow with aeration, vertical flow with aeration, and reciprocating...
September 5, 2017: Water Research
https://www.readbyqxmd.com/read/28911669/simultaneous-determination-of-ascorbic-acid-and-caffeine-in-commercial-soft-drinks-using-reversed-phase-ultraperformance-liquid-chromatography
#5
Fatma Turak, Remziye Güzel, Erdal Dinç
A new reversed-phase ultraperformance liquid chromatography method with a photodiode array detector was developed for the quantification of ascorbic acid (AA) and caffeine (CAF) in 11 different commercial drinks consisting of one energy drink and 10 ice tea drinks. Separation of the analyzed AA and CAF with an internal standard, caffeic acid, was performed on a Waters BEH C18 column (100 mm × 2.1 mm, 1.7 μm i.d.), using a mobile phase consisting of acetonitrile and 0.2M H3PO4 (11:89, v/v) with a flow rate of 0...
April 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911607/certification-of-caffeine-reference-material-purity-by-ultraviolet-visible-spectrophotometry-and-high-performance-liquid-chromatography-with-diode-array-detection-as-two-independent-analytical-methods
#6
REVIEW
A B Shehata, M S Rizk, E A Rend
Caffeine reference material certified for purity is produced worldwide, but no research work on the details of the certification process has been published in the literature. In this paper, we report the scientific details of the preparation and certification of pure caffeine reference materials. Caffeine was prepared by extraction from roasted and ground coffee by dichloromethane after heating in deionized water mixed with magnesium oxide. The extract was purified, dried, and bottled in dark glass vials. Stratified random selection was applied to select a number of vials for homogeneity and stability studies, which revealed that the prepared reference material is homogeneous and sufficiently stable...
October 2016: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28910196/effect-of-alpinia-galanga-on-mental-alertness-and-sustained-attention-with-or-without-caffeine-a-randomized-placebo-controlled-study
#7
Shalini Srivastava, Mark Mennemeier, Surekha Pimple
OBJECTIVE: Although Alpinia galanga has been reported to improve cognitive performance in animals, it has not been thoroughly studied for its potential psychostimulant effect in humans. A randomized, double-dummy, double-blind, placebo-controlled cross-over study was conducted to determine the effect of A galanga on mental alertness and sustained attention in comparison with caffeine and placebo in participants with a habitual caffeine intake. METHODS: Fifty-nine participants (18-40 years and body mass index of ≥18...
September 14, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28895043/effects-of-long-term-caffeine-consumption-on-the-adenosine-a1-receptor-in-the-rat-brain-an-in-vivo-pet-study-with-18-f-cpfpx
#8
Danje Nabbi-Schroeter, David Elmenhorst, Angela Oskamp, Stefanie Laskowski, Andreas Bauer, Tina Kroll
PURPOSE: Caffeine, a nonselective antagonist of adenosine receptors, is the most popular psychostimulant worldwide. Recently, a protective role of moderate chronic caffeine consumption against neurodegenerative diseases such as Alzheimer's and Parkinson's disease has been discussed. Thus, aim of the present study was an in vivo investigation of effects of long-term caffeine consumption on the adenosine A1 receptor (A1AR) in the rat brain. PROCEDURES: Sixteen adult, male rats underwent five positron emission tomography (PET) scans with the highly selective A1AR radioligand [(18)F]CPFPX in order to determine A1AR availability...
September 11, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28893553/caffeine-has-no-effect-on-eyeblink-conditioning-in-mice
#9
Anders Rasmussen, Anna C H G Ijpelaar, Chris I De Zeeuw, Henk-Jan Boele
Caffeine is one of the most widely used drugs in the world. In the brain, caffeine acts as an antagonist for the adenosine A1 and A2B receptors. Since A1 receptors are highly concentrated in the cortex of the cerebellum, we hypothesized that caffeine could potentially affect learning tasks that require the cerebellar cortex, such as eyeblink conditioning. To test this hypothesis, we examined the effect of low (5mg/kg) and high (50mg/kg) doses of caffeine, injected intraperitoneally before training, on eyeblink conditioning in mice...
September 8, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28892550/adolescent-sleepiness-causes-and-consequences
#10
Shana L Hansen, Dale Capener, Christopher Daly
Insufficient sleep duration and poor sleep quality are common among adolescents. The multidimensional causes of insufficient sleep duration and poor sleep quality include biological, health-related, environmental, and lifestyle factors. The most common direct consequence of insufficient and/or poor sleep quality is excessive daytime sleepiness, which may contribute to poor academic performance, behavioral health problems, substance use, and drowsy driving. Evaluation of sleepiness includes a detailed sleep history and sleep diary, with polysomnography only required for the assessment of specific sleep disorders...
September 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28891561/online-monitoring-of-hepatic-rat-metabolism-by-coupling-a-liver-biochip-and-a-mass-spectrometer
#11
Franck Merlier, Rachid Jellali, Eric Leclerc
A microfluidic liver biochip was coupled with a mass spectrometer to detect in real time the drug metabolism of hepatocytes. The hepatocytes were cultivated in the biochip for 35 h. The biochip was placed in a small-scale incubator in which the temperature and CO2 concentration were controlled. The biochip was connected serially to a mass spectrometer, a peristaltic pump and a culture medium reservoir. The injection in the mass spectrometer was performed every 10 min for 11 h. The metabolism of midazolam, phenacetin, omeprazole, dextromethorphan, repaglinide, rosuvastatin, tolbutamide and caffeine was investigated...
September 11, 2017: Analyst
https://www.readbyqxmd.com/read/28891369/caffeinated-and-decaffeinated-coffee-consumption-and-melanoma-risk-a-dose-response-meta-analysis-of-prospective-cohort-studies
#12
Agnieszka Micek, Justyna Godos, Alessandra Lafranconi, Marina Marranzano, Andrzej Pajak
To determine the association between total, caffeinated and decaffeinated coffee consumption and melanoma risk a dose-response meta-analysis on prospective cohort studies were performed. Eligible studies were identified searching PubMed and EMBASE databases from the earliest available online indexing year to March 2017. The dose-response relationship was assessed by random-effects meta-analysis and the shape of the exposure-outcome curve was modelled linearly and using restricted cubic splines. A total of seven studies eligible for meta-analysis were identified that comprised 1,418,779 participants and 9211 melanoma cases...
September 11, 2017: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/28885372/light-therapy-for-multiple-sclerosis-associated-fatigue-study-protocol-for-a-randomized-controlled-trial
#13
Farrah J Mateen, Natalie C Manalo, Sara J Grundy, Melissa A Houghton, Gladia C Hotan, Hans Erickson, Aleksandar Videnovic
BACKGROUND: Fatigue is the most commonly reported symptom among multiple sclerosis (MS) patients, more than a quarter of whom consider fatigue to be their most disabling symptom. However, there are few effective treatment options for fatigue. We aim to investigate whether supplemental exposure to bright white light will reduce MS-associated fatigue. METHODS: Eligible participants will have clinically confirmed multiple sclerosis based on the revised McDonald criteria (2010) and a score ≥36 on the Fatigue Severity Scale (FSS)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28882811/effect-of-caffeine-on-attention-and-alertness-measured-in-a-home-setting-using-web-based-cognition-tests
#14
Wilrike J Pasman, Ruud Boessen, Yoni Donner, Nard Clabbers, André Boorsma
BACKGROUND: There is an increasing interest among nutritional researchers to perform lifestyle and nutritional intervention studies in a home setting instead of testing subjects in a clinical unit. The term used in other disciplines is 'ecological validity' stressing a realistic situation. This becomes more and more feasible because devices and self-tests that enable such studies are more commonly available. Here, we present such a study in which we reproduced the effect of caffeine on attention and alertness in an at-home setting...
September 7, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28879800/acute-caffeine-ingestion-affects-surround-suppression-of-perceived-contrast
#15
Bao N Nguyen, Sui-Ann Hew, John Ly, Hee-Young Shin, Jessica C Wong, Emily Yeung, Allison M McKendrick
Caffeine is a widely used psychostimulant that is associated with increased acetylcholine levels in mammalian brain and acetycholinesterase antagonism. Acetylcholine, a neuromodulator, plays an important role in the processing of visual information. One key example in human vision, thought to at least partly involve cholinergic neuromodulation, is perceptual surround suppression of contrast, whereby the perceived contrast of a pattern is altered by the presence of a neighbouring pattern. Perceptual surround suppression is weaker with pharmacological administration of donepezil (a centrally-acting acetylcholine enzyme inhibitor) in healthy human observers...
August 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28873694/predicting-consumer-liking-and-preference-based-on-emotional-responses-and-sensory-perception-a-study-with-basic-taste-solutions
#16
Shilpa S Samant, Matthew J Chapko, Han-Seok Seo
Traditional methods of sensory testing focus on capturing information about multisensory perceptions, but do not necessarily measure emotions elicited by these food and beverages. The objective of this study was to develop an optimum model of predicting overall liking (rating) and preference (choice) based on taste intensity and evoked emotions. One hundred and two participants (51 females) were asked to taste water, sucrose, citric acid, salt, and caffeine solutions. Their emotional responses toward each sample were measured by a combination of a self-reported emotion questionnaire (EsSense25), facial expressions, and autonomic nervous system (ANS) responses...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28872376/caffeine-and-physiological-responses-to-submaximal-exercise-a-meta-analysis
#17
Mark Glaister, Conor Gissane
The aim of this study was to carry out a systematic review and meta-analysis of the effects of caffeine supplementation on physiological responses to submaximal exercise. 26 studies met the inclusion criteria of adopting double-blind, randomised, crossover designs that included a sustained (5 - 30 minutes) fixed-intensity bout of submaximal exercise (constrained to 60 - 85% V̇O2max) using a standard caffeine dose of 3 - 6 mg∙kg(-1) administered 30 - 90 minutes prior to exercise. Meta-analyses were completed using a random-effects model, and data are presented as raw mean difference (D) with associated 95% confidence limits (CL95)...
September 5, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28868290/coffee-with-high-but-not-low-caffeine-content-augments-fluid-and-electrolyte-excretion-at-rest
#18
Adam D Seal, Costas N Bardis, Anna Gavrieli, Petros Grigorakis, J D Adams, Giannis Arnaoutis, Mary Yannakoulia, Stavros A Kavouras
BACKGROUND: Low levels of caffeine ingestion do not induce dehydration at rest, while it is not clear if larger doses do have an acute diuretic effect. The aim of the present investigation was to examine the acute effect of low and high levels of caffeine, via coffee, on fluid balance in habitual coffee drinkers (at least one per day) at rest. METHODS: Ten healthy adults (eight males and two females; age: 27 ± 5 years, weight: 89.5 ± 14.8 kg, height: 1...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/28858362/the-acute-effect-of-coffee-on-endothelial-function-and-glucose-metabolism-following-a-glucose-load-in-healthy-human-volunteers
#19
Evan A J Boon, Kevin D Croft, Sujata Shinde, Jonathan M Hodgson, Natalie C Ward
A diet rich in plant polyphenols has been suggested to reduce the incidence of cardiovascular disease and type 2 diabetes mellitus, in part, via improvements in endothelial function. Coffee is a rich source of phenolic compounds including the phenolic acid, chlorogenic acid (CGA). The aim of the study was to investigate the effect of coffee as a whole beverage on endothelial function, blood pressure and blood glucose concentration. Twelve healthy men and women were recruited to a randomised, placebo-controlled, cross-over study, with three treatments tested: (i) 18 g of ground caffeinated coffee containing 300 mg CGA in 200 mL of hot water, (ii) 18 g of decaffeinated coffee containing 287 mg CGA in 200 mL of hot water, and (iii) 200 mL of hot water (control)...
August 31, 2017: Food & Function
https://www.readbyqxmd.com/read/28853006/are-the-current-guidelines-on-caffeine-use-in-sport-optimal-for-everyone-inter-individual-variation-in-caffeine-ergogenicity-and-a-move-towards-personalised-sports-nutrition
#20
Craig Pickering, John Kiely
Caffeine use is widespread in sport, with a strong evidence base demonstrating its ergogenic effect. Based on existing research, current guidelines recommend ingestion of 3-9 mg/kg approximately 60 min prior to exercise. However, the magnitude of performance enhancement following caffeine ingestion differs substantially between individuals, with the spectrum of responses ranging between highly ergogenic to ergolytic. These extensive inter-individual response distinctions are mediated by variation in individual genotype, environmental factors, and the legacy of prior experiences partially mediated via epigenetic mechanisms...
August 29, 2017: Sports Medicine
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