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caffeine and performance

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https://www.readbyqxmd.com/read/28741186/effects-of-caffeine-supplementation-on-performance-in-ball-games
#1
REVIEW
Jingyi Shannon Chia, Laura Ann Barrett, Jia Yi Chow, Stephen Francis Burns
Although a large body of evidence exists documenting the ergogenic properties of caffeine, most studies have focused on endurance performance. However, findings from endurance sports cannot be generalized to performance in ball games where, apart from having a high level of endurance, successful athletic performances require a combination of physiological, technical and cognitive capabilities. The purpose of this review was to critically evaluate studies that have examined the effect of a single dose of caffeine in isolation on one or more of the following performance measures: total distance, sprint performance, agility, vertical jump performance and accuracy in ball games...
July 24, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28723815/effect-of-energy-drink-consumption-on-power-and-velocity-of-selected-sport-performance-activities
#2
Bert H Jacobson, Garrett M Hester, Ty B Palmer, Kathryn Williams, Zachary K Pope, John H Sellers, Eric C Conchola, Conrad Woolsey, Carlos Estrada
Energy drinks comprise a multibillion dollar market focused on younger, active and competitive individuals. Marketing includes claims of improved alertness and performance. The purpose of this study was to assess power (W) and velocity (m·s) of a simulated, isolated forehand stroke (FHS) and a counter movement vertical jump (CVJ) before and after ingestion of a commercially available energy shot (ES) or a placebo (PL). Healthy college-aged male and female (N=36) volunteers were randomly placed in the ES or PL...
July 17, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28723408/in-line-raman-spectroscopic-monitoring-and-feedback-control-of-a-continuous-twin-screw-pharmaceutical-powder-blending-and-tableting-process
#3
Brigitta Nagy, Attila Farkas, Martin Gyürkés, Szofia Komaromy-Hiller, Balázs Démuth, Bence Szabó, Dávid Nusser, Enikő Borbás, György Marosi, Zsombor Kristóf Nagy
The integration of Process Analytical Technology (PAT) initiative into the continuous production of pharmaceuticals is indispensable for reliable production. The present paper reports the implementation of in-line Raman spectroscopy in a continuous blending and tableting process of a three-component model pharmaceutical system, containing caffeine as model active pharmaceutical ingredient (API), glucose as model excipient and magnesium stearate as lubricant. The real-time analysis of API content, blend homogeneity, and tablet content uniformity was performed using a Partial Least Squares (PLS) quantitative method...
July 16, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28718641/in-silico-skin-model-a-multiscale-simulation-study-of-drug-transport
#4
Kishore Gajula, Rakesh Gupta, D B Sridhar, Beena Rai
Accurate in-silico models are required to predict the release of drug molecules through skin in order to supplement the in-vivo experiments for faster development/testing of drugs. The upper most layer of the skin, stratum corneum (SC), offers main resistance for permeation of actives. Most of the SC's molecular level models comprise of cholesterol, and phospholipids only, which is far from the reality. In this study we have implemented a multiscale modelling framework to obtain the release profile of three drugs namely Caffeine, Fentanyl and Naphthol through skin SC...
July 18, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28705089/electrochemical-degradation-of-psychoactive-drug-caffeine-in-aqueous-solution-using-graphite-electrode
#5
Selvendiran Periyasamy, Muthukumar Muthuchamy
In this study, the electrochemical degradation of caffeine (1, 3, 7-trimethylxanthine) in aqueous solution by a graphite electrode was investigated. Electrochemical degradation was tested by cyclic voltametry technique performed in the potential range of -1.0 to +1.0 V versus Ag/AgCl, which confirmed the electro-activity of the selected caffeine. The effects of the treatment process variables, such as initial pH, current density, electrolyte concentration and electrolysis time on the degradation of caffeine were explored...
July 14, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28694153/caffeinated-energy-drink-intake-modulates-motor-circuits-at-rest-before-and-after-a-movement
#6
Carmen Concerto, Carmenrita Infortuna, Eileen Chusid, Diego Coira, Jacqueline Babayev, Rowan Metwaly, Hesam Naenifard, Eugenio Aguglia, Fortunato Battaglia
Energy drinks are thought to improve certain aspects of athletic and cognitive performances. Moreover, less is understood about physiological mechanisms that might underlie these effects. The aim of this study was to examine the influence of sugar-free energy drink (SFED) ingestion on corticomotor excitability and plasticity. Fourteen college students consumed a commercially available SFED or a "dummy" drink. By using Transcranial magnetic Stimulation (TMS) we investigated resting motor threshold (RMT), motor evoked potential (MEP) amplitude and cortical silent period (CSP)...
July 8, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28690955/energy-drinks-and-the-risk-of-cardiovascular-disease-a-review-of-current-literature
#7
REVIEW
Muhammad A Mangi, Hiba Rehman, Muhammad Rafique, Michael Illovsky
Energy drinks (EDs) are commonly used as a dietary supplement by young adolescents and adults. They are often used as a source of energy in order to enhance physical and mental performance. EDs contain a variety of substances, but caffeine is the main component. Safety has been the biggest concern associated with consuming EDs. Case reports, observational studies, and meta-analyses have been done in order to determine the effects of EDs on cardiovascular changes. The detrimental effects of EDs are cardiac arrhythmias, myocardial infarction, prolonged QT interval, aortic dissection, and death...
June 7, 2017: Curēus
https://www.readbyqxmd.com/read/28677810/caffeine-induces-sustained-apoptosis-of-human-gastric-cancer-cells-by-activating-the-caspase%C3%A2-9-caspase%C3%A2-3-signalling-pathway
#8
Hanyang Liu, Yan Zhou, Liming Tang
Caffeine is one of the most widely consumed substances found in beverages, and has demonstrated anticancer effects in several types of cancer. The present study aimed to examine the anticancer effects of caffeine on gastric cancer (GC) cells (MGC‑803 and SGC‑7901) in vitro, and to determine whether the apoptosis‑related caspase‑9/-3 pathway is associated with these effects. The sustained antiproliferative effects of caffeine on gastric cancer were also investigated. GC cell viability and proliferation were evaluated using cell counting and colony forming assays, following treatment with various concentrations of caffeine...
September 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28664363/a-novel-strain-of-aureobasidium-sp-teo12-for-theophylline-production-from-caffeine
#9
Morahem Ashengroph
A total of 40 fungal cultures were isolated for their ability to grow on caffeine as a sole source carbon and nitrogen, and further screened for theophylline-producing activities under the growing cell system. Based on thin-layer chromatography and high-performance liquid chromatography analyses, the potent strain Aureobasidium sp. TeO12 was chosen for its capability to generate theophylline via biotransformation of caffeine. It was identified based on phenotypic characteristics and its ITS1-5.8S-ITS2 rDNA sequencing data (GenBank accession number no...
July 2017: 3 Biotech
https://www.readbyqxmd.com/read/28659771/cognitive-impairment-in-patients-with-chronic-neuropathic-or-radicular-pain-an-interaction-of-pain-and-age
#10
Orla Moriarty, Nancy Ruane, David O'Gorman, Chris H Maharaj, Caroline Mitchell, Kiran M Sarma, David P Finn, Brian E McGuire
A growing body of empirical research has confirmed an association between chronic pain and cognitive dysfunction. The aim of the present study was to determine whether cognitive function is affected in patients with a diagnosis of chronic neuropathic or radicular pain relative to healthy control participants matched by age, gender, and years of education. We also examined the interaction of pain with age in terms of cognitive performance. Some limitations of previous clinical research investigating the effects of chronic pain on cognitive function include differences in the pain and cognitive scale materials used, and the heterogeneity of patient participants, both in terms of their demographics and pathological conditions...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28653770/studies-on-n-acetyltransferase-nat2-genotype-relationships-in-emiratis-confirmation-of-the-existence-of-phenotype-variation-among-slow-acetylators
#11
Mohammad M Al-Ahmad, Naheed Amir, Subramanian Dhanasekaran, Anne John, Yousef M Abdulrazzaq, Bassam R Ali, Salim Bastaki
BACKGROUND AND PURPOSE: Individuals with slow N-acetylation phenotype often experience toxicity from drugs such as isoniazid, sulfonamides, procainamide, and hydralazine, whereas rapid acetylators may not respond to these medications. The highly polymorphic N-acetyltransferase 2 enzyme encoded by the NAT2 gene is one of the N-acetylators in humans with a clear impact on the metabolism of a significant number of important drugs. However, there are limited studies on N-acetylation phenotypes and NAT2 genotypes among Emiratis, and thus this study was carried out to fill this gap...
June 27, 2017: Annals of Human Genetics
https://www.readbyqxmd.com/read/28646871/coffee-and-caffeine-intake-and-male-infertility-a-systematic-review
#12
REVIEW
Elena Ricci, Paola Viganò, Sonia Cipriani, Edgardo Somigliana, Francesca Chiaffarino, Alessandro Bulfoni, Fabio Parazzini
BACKGROUND: Semen quality, a predictor of male fertility, has been suggested declining worldwide. Among other life style factors, male coffee/caffeine consumption was hypothesized to influence semen parameters, but also sperm DNA integrity. To summarize available evidence, we performed a systematic review of observational studies on the relation between coffee/caffeine intake and parameters of male fertility including sperm ploidy, sperm DNA integrity, semen quality and time to pregnancy...
June 24, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28638561/importance-and-methodologies-of-endodontic-microleakage-studies-a-systematic-review
#13
REVIEW
Farnaz Jafari, Sanaz Jafari
INTRODUCTION: It is very important to obtain a tight seal in obturated root canal, making it necessary to conduct clinical or laboratory studies on the sealability of endodontic materials. Different methodologies have been historically used to assess microleakage of different endodontic materials. The aim of the present study was to comprehensively review different material testing methods used in microleakage studies, their interpretation and importance in endodontic literature. MATERIAL AND METHODS: A systematic search was conducted in Medline, Cochrane, and Web of Science databases...
June 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28638217/diet-in-irritable-bowel-syndrome-what-to-recommend-not-what-to-forbid-to-patients
#14
REVIEW
Anamaria Cozma-Petruţ, Felicia Loghin, Doina Miere, Dan Lucian Dumitraşcu
A substantial proportion of patients with irritable bowel syndrome (IBS) associate their symptoms with the ingestion of specific foods. Therefore, in recent years, scientific research has increasingly focused on the role of diet in IBS and dietary management is now considered an important tool in IBS treatment. This article reviews the main dietary approaches in IBS emphasizing evidence from experimental and observational studies and summarizing the main diet and lifestyle recommendations provided by dietary guidelines and scientific literature...
June 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28617952/systolic-ca-2-i-regulates-diastolic-levels-in-rat-ventricular-myocytes
#15
Rajiv Sankaranarayanan, Kornél Kistamás, David J Greensmith, Luigi A Venetucci, David A Eisner
KEY POINTS: For the heart to function as a pump, intracellular calcium concentration ([Ca(2+) ]i ) must increase during systole to activate contraction and then fall, during diastole, to allow the myofilaments to relax and the heart to refill with blood. The present study investigates the control of diastolic [Ca(2+) ]i in rat ventricular myocytes. We show that diastolic [Ca(2+) ]i is increased by manoeuvres that decrease sarcoplasmic reticulum function. This is accompanied by a decrease of systolic [Ca(2+) ]i such that the time-averaged [Ca(2+) ]i remains constant...
June 15, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28609150/caffeine-use-in-military-personnel-with-ptsd-prevalence-and-impact-on-sleep
#16
Carmen P McLean, Laurie Zandberg, John D Roache, Hayley Fitzgerald, Kristi E Pruiksma, Daniel J Taylor, Katherine A Dondanville, Brett T Litz, Jim Mintz, Stacey Young-McCaughan, Jeffrey S Yarvis, Alan L Peterson, Edna B Foa
BACKGROUND: Caffeine use is highly prevalent among active duty military personnel and can be beneficial to performance in the short term. However, regular caffeine use has been found to contribute to sleep disturbances, which are elevated among the significant number of military personnel with posttraumatic stress disorder (PTSD). The current study is the first to examine caffeine use and its relationship with sleep disturbances in military personnel seeking treatment for PTSD. PARTICIPANTS: Active duty military personnel (N = 366) who had returned from deployments to Afghanistan or Iraq and were seeking treatment for PTSD...
June 13, 2017: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/28598402/cognitive-performance-enhancement-induced-by-caffeine-carbohydrate-and-guarana-mouth-rinsing-during-submaximal-exercise
#17
Laura Pomportes, Jeanick Brisswalter, Laurence Casini, Arnaud Hays, Karen Davranche
The aim of this study was to investigate the influence of serial mouth rinsing (MR) with nutritional supplements on cognitive performance (i.e., cognitive control and time perception) during a 40-min submaximal exercise. Twenty-four participants completed 4 counterbalanced experimental sessions, during which they performed MR with either placebo (PL), carbohydrate (CHO: 1.6 g/25 mL), guarana complex (GUAc: 0.4 g/25 mL) or caffeine (CAF: 67 mg/25 mL) before and twice during exercise. The present study provided some important new insights regarding the specific changes in cognitive performance induced by nutritional supplements...
June 9, 2017: Nutrients
https://www.readbyqxmd.com/read/28582733/predicting-the-fate-of-micropollutants-during-wastewater-treatment-calibration-and-sensitivity-analysis
#18
Zeina Baalbaki, Elena Torfs, Viviane Yargeau, Peter A Vanrolleghem
The presence of micropollutants in the environment and their toxic impacts on the aquatic environment have raised concern about their inefficient removal in wastewater treatment plants. In this study, the fate of micropollutants of four different classes was simulated in a conventional activated sludge plant using a bioreactor micropollutant fate model coupled to a settler model. The latter was based on the Bürger-Diehl model extended for the first time to include micropollutant fate processes. Calibration of model parameters was completed by matching modelling results with full-scale measurements (i...
June 2, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28569556/guaran%C3%A3-a-highly-caffeinated-food-presents-in-vitro-antitumor-activity-in-colorectal-and-breast-cancer-cell-lines-by-inhibiting-akt-mtor-s6k-and-mapks-pathways
#19
Francine C Cadoná, Jose L Rosa, Taiane Schneider, Monica Cubillos-Rojas, Susana Sánchez-Tena, Verônica F Azzolin, Charles E Assmann, Alencar K Machado, Euler E Ribeiro, Ivana Beatrice M da Cruz
The mammalian target of rapamycin (mTOR) and mitogen-activated protein kinases (MAPKs) pathways are frequently upregulated in cancer. Some authors have reported that some antioxidant molecules could be potential inhibitors of these pathways. Therefore, we investigated the in vitro antitumor effect of guaraná by inhibiting the AKT/mTOR/S6K and MAPKs pathways. Colorectal and breast cancer cell lineages, HT-29 and MCF-7 cells, respectively, were exposed to different guaraná concentrations (0.1, 1, 10, and 100 µg/mL) as well as its main bioactive molecule, caffeine, in proportional concentrations to those found in the extract...
July 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28547666/effects-of-caffeine-intake-prior-to-stress-cardiac-magnetic-resonance-perfusion-imaging-on-regadenoson-versus-adenosine-induced-hyperemia-as-measured-by-t1-mapping
#20
R van Dijk, D Kuijpers, T A M Kaandorp, P R M van Dijkman, R Vliegenthart, P van der Harst, M Oudkerk
The antagonistic effects of caffeine on adenosine receptors are a possible cause of false-negative stress perfusion imaging. The purpose of this study was to determine the effects of coffee intake <4 h prior to stress perfusion cardiac magnetic resonance imaging (CMR) in regadenoson- versus adenosine-induced hyperemia as measured with T1-mapping. 98 consecutive patients with suspected coronary artery disease referred for either adenosine or regadenoson perfusion CMR were included in this analysis. Twenty-four patients reported coffee consumption <4 h before CMR (15 patients with adenosine, and 9 patients with regadenoson); 74 patients reported no coffee intake (50 patients with adenosine, and 24 patients with regadenoson)...
May 25, 2017: International Journal of Cardiovascular Imaging
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