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https://www.readbyqxmd.com/read/28107957/methodology-for-monitoring-gold-nanoparticles-and-dissolved-gold-species-in-culture-medium-and-cells-used-for-nanotoxicity-tests-by-liquid-chromatography-hyphenated-to-inductively-coupled-plasma-mass-spectrometry
#1
Sara López-Sanz, Nuria Rodríguez Fariñas, Rosario Serrano Vargas, Rosa Del Carmen Rodríguez Martín-Doimeadios, Ángel Ríos
An analytical methodology based on coupling reversed-phase liquid chromatography (HPLC) to an inductively coupled plasma mass spectrometry (ICP-MS) has been developed for the characterization and identification of gold nanoparticles (AuNPs) and gold dissolved species (Au(3+)) in culture medium (Dulbecco's Modified Eagle Medium, DMEM) and HeLa cells (a human cervical adenocarcinoma cell line) used in nanotoxicity tests. The influence of the culture medium was also studied and the method applied for nanotoxicity tests...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28105861/a-novel-benzimidazole-and-other-constituents-with-antiproliferative-and-antioxidant-properties-from-thymelaea-microphylla-coss-et-dur
#2
Labib Noman, Feyza Oke-Altuntas, Amar Zellagui, Ayse Sahin Yaglioglu, Ibrahim Demirtas, Susana M Cardoso, Salah Akkal, Noureddine Gherraf, Salah Rhouati
A new compound (microphybenzimidazole, 7) along with the six known compounds matairesinol (1), prestegane B (2), umbelliferone (3), daphnoretin (4), microphynolide A (5) and microphynolide B (6) were isolated from Thymelaea microphylla. The structures of the pure compounds were elucidated by spectroscopic and mass-spectrometric analyses, including 1D-, 2D-NMR, and HPLC-TOF/MS. Compounds 2 and 4, as well as three fractions (F6, F6-C5, and F6-W42) obtained from a 50% (v:v) CH2Cl2:MeOH extract exhibited a selective activity against rat brain glioma cells (C6)...
January 20, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28104743/active-brown-fat-during-18fdg-pet-ct-imaging-defines-a-patient-group-with-characteristic-traits-and-an-increased-probability-of-brown-fat-redetection
#3
Carlos Gerngroß, Johanna Schretter, Martin Klingenspor, Markus Schwaiger, Tobias Fromme
Brown adipose tissue (BAT) provides a means of non-shivering thermogenesis. In humans, active BAT can be visualized by (18)F-fluoro-desoxyglucose (FDG) uptake as detected by positron emission tomography (PET) combined with computer tomography (CT). The retrospective analysis of clinical scans is a valuable source to identify anthropometric parameters that influence BAT mass and activity and thus the potential efficacy of envisioned drugs targeting this tissue to treat metabolic disease. We analyzed 2854 FDG-PET/CT scans from 1644 patients and identified 98 scans from 81 patients with active BAT...
January 19, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28099504/direction-specific-impairments-in-cervical-range-of-motion-in-women-with-chronic-neck-pain-influence-of-head-posture-and-gravitationally-induced-torque
#4
Thomas Rudolfsson, Martin Björklund, Åsa Svedmark, Divya Srinivasan, Mats Djupsjöbacka
BACKGROUND: Cervical range of motion (ROM) is commonly assessed in clinical practice and research. In a previous study we decomposed active cervical sagittal ROM into contributions from lower and upper levels of the cervical spine and found level- and direction-specific impairments in women with chronic non-specific neck pain. The present study aimed to validate these results and investigate if the specific impairments can be explained by the neutral posture (defining zero flexion/extension) or a movement strategy to avoid large gravitationally induced torques on the cervical spine...
2017: PloS One
https://www.readbyqxmd.com/read/28099288/assessing-the-agreement-between-radiologic-and-clinical-measurements-of-lumbar-and-cervical-epidural-depths-in-patients-undergoing-prone-interlaminar-epidural-steroid-injection
#5
James Harvey Jones, Naileshni Singh, Anna Nidecker, Chin-Shang Li, Scott Fishman
BACKGROUND: Fluoroscopy-guided epidural steroid injection (ESI) commonly is performed to treat radicular pain yet can lead to adverse events if the needle is not advanced with precision. Accurate preoperative assessment of the distance from the skin to the epidural space holds the potential for reducing the risks of adverse effects from ESI. It was hypothesized that the distance from the skin to the epidural space as measured on preoperative magnetic resonance imaging (MRI) would agree with the distance traveled by a Tuohy needle to reach the epidural space during midline, interlaminar ESI...
January 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28097935/finite-element-simulations-of-the-head-brain-responses-to-the-top-impacts-of-a-construction-helmet-effects-of-the-neck-and-body-mass
#6
John Z Wu, Christopher S Pan, Bryan M Wimer, Charles L Rosen
Traumatic brain injuries are among the most common severely disabling injuries in the United States. Construction helmets are considered essential personal protective equipment for reducing traumatic brain injury risks at work sites. In this study, we proposed a practical finite element modeling approach that would be suitable for engineers to optimize construction helmet design. The finite element model includes all essential anatomical structures of a human head (i.e. skin, scalp, skull, cerebrospinal fluid, brain, medulla, spinal cord, cervical vertebrae, and discs) and all major engineering components of a construction helmet (i...
January 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28095343/patient-tailored-management-of-an-asymptomatic-massive-substernal-goiter-presenting-as-brachiocephalic-vein-occlusion-report-of-a-case-and-review-of-sternotomy-indications
#7
Georgios Sahsamanis, Eleftherios Chouliaras, Konstantinos Katis, Stavros Samaras, Stavros Daliakopoulos, Georgios Dimitrakopoulos
INTRODUCTION: Substernal goiters are characterized by the protrusion of at least 50% of the thyroid mass below the level of the thoracic inlet. Still their definition is controversial. CASE PRESENTATION: The case refers to a 44year old male who presented to our department due to swelling and a feeling of 'heaviness' of his left upper extremity for the past 6 months. CT scan revealed a massive substernal goiter extending to the great vessels. Intraoperatively, a median sternotomy was performed due to the size of the gland and the close adhesion of the isthmus and lower left thyroid lobe to the brachiocephalic vein...
January 4, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28080204/identification-of-hur-target-circular-rnas-uncovers-suppression-of-pabpn1-translation-by-circpabpn1
#8
Kotb Abdelmohsen, Amaresh C Panda, Rachel Munk, Ioannis Grammatikakis, Dawood B Dudekula, Supriyo De, Jiyoung Kim, Ji Heon Noh, Kyoung Mi Kim, Jennifer L Martindale, Myriam Gorospe
HuR influences gene expression programs and hence cellular phenotypes by binding to hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular RNAs (circRNAs) and impacts on their function is unknown. Here, we have identified en masse circRNAs binding HuR in human cervical carcinoma HeLa cells. One of the most prominent HuR target circRNAs was hsa_circ_0031288, renamed CircPABPN1 as it arises from the PABPN1 pre-mRNA. Further analyses revealed that HuR did not influence CircPABPN1 abundance; interestingly, however, high levels of CircPABPN1 suppressed HuR binding to PABPN1 mRNA...
January 12, 2017: RNA Biology
https://www.readbyqxmd.com/read/28078796/hyperparathyroidism-caused-by-distant-pulmonary-lesions-and-parathyromatosis-after-ethanol-injection-parathyroidectomy-for-secondary-hyperparathyroidism
#9
Michio Nakamura, Kiho Tanaka, Takeshi Fujii
Secondary hyperparathyroidism (SHPT) treatment includes parathyroidectomy and percutaneous ethanol injection therapy (PEIT), which are invasive procedures. The condition in which benign hyperfunctioning parathyroid tissue is distributed throughout the neck and mediastinum is termed parathyromatosis. Here, we present the case of a 51-year-old woman who began hemodialysis in 1986 due to chronic kidney disease of unknown etiology and developed SHPT in 1999. She underwent 6 rounds of PEIT followed by total a parathyroidectomy with partial forearm autotransplantation...
January 11, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28062438/primary-non-hodgkin-s-lymphoma-of-the-tongue-a-diagnostic-dilemma-of-unusual-case-presentation
#10
Natheer Hashim Al-Rawi
Primary non-Hodgkin's lymphoma of the tongue is extremely uncommon, which makes its diagnosis quite challenging. A panel of 11 markers is used based on morphological differential diagnosis to elucidate the lymphoma subtype. A case of 43-year-old Egyptian man suffering from nodular mass on the right side of the tongue of 4 months duration is presented. No cervical lymphadenopathy was detected. No abdominal organomegaly was noted. The histological evaluation of incisional biopsy revealed a sheet of pleomorphic lymphoid cells with abnormal mitotic figures...
January 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28057913/humoral-hypercalcemia-in-uterine-cancers-a-case-report-and-literature-review
#11
Vijeyaluxmy Motilal Nehru, Gwenalyn Garcia, Juan Ding, Fanyi Kong, Qun Dai
BACKGROUND Paraneoplastic hypercalcemia is a well-described complication associated with a variety of malignancies. However, its incidence in gynecological malignancies is low. CASE REPORT A 53-year-old woman presented with progressive abdominal distention and irregular vaginal bleeding of several weeks' duration. A contrast CT abdomen and pelvis was significant for a mass in the lower uterine/cervical region, multiple peritoneal and omental masses, enlarged pelvic and paraaortic lymph nodes, and large-volume ascites...
January 6, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28054384/computational-anatomy-of-the-dens-axis-evaluated-by-quantitative-computed-tomography-implications-for-anterior-screw-fixation
#12
Dominic Gehweiler, Dirk Wähnert, Norbert Meier, Maarten Spruit, Michael Johannes Raschke, Robert Geoff Richards, Hansrudi Noser, Lukas Kamer
The surgical fracture fixation of the odontoid process (dens) of the second cervical vertebra (C2/axis) is a challenging procedure, particularly in elderly patients affected by bone loss, and includes screw positioning close to vital structures. The aim of this study was to provide an extended anatomical knowledge of C2, the bone mass distribution and bone loss, and to understand the implications for anterior screw fixation. 120 standard clinical quantitative computed tomography (QCT) scans of the intact cervical spine from 60 female and 60 male European patients, aged 18-90 years, were used to compute a three-dimensional statistical model and an averaged bone mass model of C2...
January 5, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28053701/primary-thyroid-lymphoma-a-case-report-and-review-of-the-literature
#13
Rita Peixoto, João Correia Pinto, Virgínia Soares, Pedro Koch, António Taveira Gomes
INTRODUCTION: A rapidly enlarging mass of the anterior compartment of the neck with compressive symptoms may represent, among other diagnosis, a neoplasm of the thyroid gland. PRESENTATION OF CASE: We describe the case of a 59-year-old woman referred to the endocrine surgical unit because of compressive cervical symptoms for 3 months. The cervical ultrasound revealed a sub-sternal goiter with heterogeneous echo structure and the fine-needle aspirating cytology was inconclusive...
January 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28052724/unusual-presentations-of-enlarged-parathyroid-cysts-two-case-reports
#14
Aurore Pire, Antoine Buemi, Alessandra Camboni, Tom Darius, Luc De Pauw, Michel Mourad
INTRODUCTION: Parathyroid cysts are infrequently encountered and have a variable presentation pattern depending on their size, location and secreting character. PATIENTS AND METHODS: We report two cases of parathyroid cysts characterized by their uncommon clinical presentation. RESULTS: In the first case the patient presented with a large cervical cystic mass without hypercalcemia, while in the second case, the patient experienced a hypercalcemic crisis associated with acute renal failure...
January 5, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28052083/pregnancy-outcomes-after-treatment-for-cervical-cancer-precursor-lesions-an-observational-study
#15
Sheila Weinmann, Allison Naleway, Geeta Swamy, Girishanthy Krishnarajah, Bhakti Arondekar, Jovelle Fernandez, Evan Myers
OBJECTIVE: To examine whether surgical procedures involving the uterine cervix were associated with pregnancy outcomes, including preterm birth, low birth weight, cesarean delivery and pregnancy loss. DESIGN: Population-based observational study nested in retrospective matched cohort. SETTING: Kaiser Permanente Northwest integrated health plan in Oregon/Washington, U.S.A. POPULATION: Female health plan members age 14-53 years with documented pregnancies from 1998-2009...
2017: PloS One
https://www.readbyqxmd.com/read/28045425/case-images-cervical-adenocarcinoma-presenting-with-a-terrible-combination-a-giant-cardiac-mass-cardiac-tamponade-and-pulmonary-embolism
#16
Muhammed Keskin, Mert İlker Hayıroğlu, Taha Keskin, Emir Renda, Ahmet Ahmet
No abstract text is available yet for this article.
December 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28042563/unusual-presentation-of-a-cervical-mass-revealed-as-external-jugular-venous-aneurysm
#17
Su Wan Kim, Jee Won Chang, Seogjae Lee
Venous aneurysms of the jugular vein are one of the rare causes of neck swelling, and primary venous aneurysms of the external jugular vein are extremely rare. A 46-year-old woman presented with a painless and suddenly growing mass in the left neck. A computed tomography angiography revealed a fusiform venous aneurysm of the external jugular vein containing intraluminal thrombus. We performed resection of the aneurysm and ligation of the external jugular vein. Removal of the aneurysm of the neck vein was necessary because venous aneurysms with thrombosis may lead to serious thrombotic complications such as pulmonary embolism...
December 2016: Vascular Specialist International
https://www.readbyqxmd.com/read/28040230/-cervical-thoracic-duct-cyst-an-uncommon-entity
#18
Manuel Carreira-Delgado, Elvira Fernández-Rodríguez, Marta Martínez-Míguez, María Jesús Álvarez-Martín, José Manuel Nuño Vázquez-Garza
BACKGROUND: Cervical thoracic duct cysts are a rare anomaly. OBJECTIVE: To report a case of cervical thoracic duct cyst, and perform a literature review. CLINICAL CASE: A 78-year-old female, with a one-year history of a left-sided asymptomatic supraclavicular cystic mass. Computerized tomography revealed a cystic mass 42mm in diameter. We performed a fine needle aspiration puncture, obtaining a thick, milky, whitish liquid. The patient underwent surgery; finding a left-sided supraclavicular cystic mass, with some lymph vessels heading towards the jugulo subclavian venous junction...
December 28, 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28035309/adenoid-cystic-carcinoma-of-the-sublingual-gland-a-case-report
#19
Ji-Young Song
Adenoid cystic carcinoma (ACC) of the sublingual gland is an extremely rare neoplasm. The clinicopathological characteristics of ACC are slow-growing swelling with or without ulceration, perineural spread, local recurrence, and distant metastasis. This report describes a 58-year-old male who had a slowly growing swelling without ulceration on the right side of the mouth floor that had been present for 1 month. In a radiological examination, the mass showed multilocular cystic features and no bony or tongue muscle invasion...
December 2016: Imaging Science in Dentistry
https://www.readbyqxmd.com/read/28034968/is-there-a-relationship-between-body-mass-index-and-fluoroscopy-time-during-cervical-interlaminar-epidural-steroid-injections
#20
Zachary L McCormick, Ryan Mattie, Ali Ebrahimi, David T Lee, Austin Marcolina, Joel Press, D J Kennedy, Matthew Smuck, David R Walega, Daniel Cushman
: BACKGROUND : The challenge of obtaining medical imaging in individuals with higher body mass index (BMI) is described, but there is minimal data regarding the relationship between BMI and fluoroscopy time during cervical interlaminar epidural steroid injection (CIESI). OBJECTIVE : To determine the relationship between BMI and fluoroscopy time during CIESI. METHODS : Retrospective cohort study of patients who underwent fluoroscopically guided CIESI between January 2014 and February 2015 at an academic pain medicine center...
December 29, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
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